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coiled-coil domain-containing protein 175 isoform X4 [Homo sapiens]
Protein Classification
List of domain hits
Name
Accession
Description
Interval
E-value
SMC_N super family
cl47134 RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
112-391
3.25e-08
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
TIGR02169 :Pssm-ID: 481474 [Multi-domain]
Cd Length: 1164
Bit Score: 57.00
E-value: 3.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 112 SI KRE L E ECVRDAR - RLNLFEINT I KMRITRT E N E I E L L KKK I TD L T K YN E ALGEKQ EEL AR K - HARFVLSLNQTM EK KA 189
Cdd:TIGR02169 218 KE KRE Y E GYELLKE k EALERQKEA I ERQLASL E E E L E K L TEE I SE L E K RL E EIEQLL EEL NK K i KDLGEEEQLRVK EK IG 297
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 190 TTTVY I NETYTK I NL K ----------- REDI A LQK K CIQ E A EEL m E K E RA E YLI R KQE LT AQIN E FENTR E VK R M E TYQK 258
Cdd:TIGR02169 298 ELEAE I ASLERS I AE K ereledaeerl AKLE A EID K LLA E I EEL - E R E IE E ERK R RDK LT EEYA E LKEEL E DL R A E LEEV 376
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 259 K KE LDKLQTKMSKIK E TVTVSAAVLSDHNL E IA RL H E SIRYWEQ E VSE L KKDL A IL EAK LC - FFTDNKE K LDD I SND E K n 337
Cdd:TIGR02169 377 D KE FAETRDELKDYR E KLEKLKREINELKR E LD RL Q E ELQRLSE E LAD L NAAI A GI EAK IN e LEEEKED K ALE I KKQ E W - 455
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 767981427 338 efln K IK QL VET L HAARM E YK DL R E KMKTLARQYKIVLS E EEK A FL Q KQKIHDE 391
Cdd:TIGR02169 456 ---- K LE QL AAD L SKYEQ E LY DL K E EYDRVEKELSKLQR E LAE A EA Q ARASEER 505
Smc super family
cl34174 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
220-598
5.08e-07
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
COG1196 :Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 53.02
E-value: 5.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 220 EEL M E K E RAEY L IRKQ EL T A QIN E F E NTR E vkrmety QKKK EL DK L QTKMSKIKETVTVSAAV L SDHN LE IARLHESIRY 299
Cdd:COG1196 220 EEL K E L E AELL L LKLR EL E A ELE E L E AEL E ------- ELEA EL EE L EAELAELEAELEELRLE L EELE LE LEEAQAEEYE 292
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 300 WEQ E VSE L KK D L A I LE AKLCFFTDNK E K L DD isnd E KN E FLNKIKQ L V E T L HAARM E YKDLR E KMKTLARQYKIVLSEEE 379
Cdd:COG1196 293 LLA E LAR L EQ D I A R LE ERRRELEERL E E L EE ---- E LA E LEEELEE L E E E L EELEE E LEEAE E ELEEAEAELAEAEEALL 368
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 380 K A flq KQKIHDENQKQLTFISQKEYF L SQKRVDIKNM EE GLITLQE L QQATKTVYQQQIKILS A NL E R E SQR cvitqwkm 459
Cdd:COG1196 369 E A --- EAELAEAEEELEELAEELLEA L RAAAELAAQL EE LEEAEEA L LERLERLEEELEELEE A LA E L E EEE -------- 437
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 460 aclrkkharwt AKIKAEIQAIT E KIQNA E VRRIE LL NETSFRQQ E ISGFV A QIEK L TT EL K E EEKAFVNKEKMLMKELSK 539
Cdd:COG1196 438 ----------- EEEEEALEEAA E EEAEL E EEEEA LL ELLAELLE E AALLE A ALAE L LE EL A E AAARLLLLLEAEADYEGF 506
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 767981427 540 Y E EIFVKETQINKEKEEEL V EY L PQLQV A EQEYK E KRRKLEELSNIIT DDE RRDMG I RR 598
Cdd:COG1196 507 L E GVKAALLLAGLRGLAGA V AV L IGVEA A YEAAL E AALAAALQNIVVE DDE VAAAA I EY 565
Name
Accession
Description
Interval
E-value
SMC_prok_A
TIGR02169 chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
112-391
3.25e-08
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain]
Cd Length: 1164
Bit Score: 57.00
E-value: 3.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 112 SI KRE L E ECVRDAR - RLNLFEINT I KMRITRT E N E I E L L KKK I TD L T K YN E ALGEKQ EEL AR K - HARFVLSLNQTM EK KA 189
Cdd:TIGR02169 218 KE KRE Y E GYELLKE k EALERQKEA I ERQLASL E E E L E K L TEE I SE L E K RL E EIEQLL EEL NK K i KDLGEEEQLRVK EK IG 297
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 190 TTTVY I NETYTK I NL K ----------- REDI A LQK K CIQ E A EEL m E K E RA E YLI R KQE LT AQIN E FENTR E VK R M E TYQK 258
Cdd:TIGR02169 298 ELEAE I ASLERS I AE K ereledaeerl AKLE A EID K LLA E I EEL - E R E IE E ERK R RDK LT EEYA E LKEEL E DL R A E LEEV 376
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 259 K KE LDKLQTKMSKIK E TVTVSAAVLSDHNL E IA RL H E SIRYWEQ E VSE L KKDL A IL EAK LC - FFTDNKE K LDD I SND E K n 337
Cdd:TIGR02169 377 D KE FAETRDELKDYR E KLEKLKREINELKR E LD RL Q E ELQRLSE E LAD L NAAI A GI EAK IN e LEEEKED K ALE I KKQ E W - 455
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 767981427 338 efln K IK QL VET L HAARM E YK DL R E KMKTLARQYKIVLS E EEK A FL Q KQKIHDE 391
Cdd:TIGR02169 456 ---- K LE QL AAD L SKYEQ E LY DL K E EYDRVEKELSKLQR E LAE A EA Q ARASEER 505
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
220-598
5.08e-07
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 53.02
E-value: 5.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 220 EEL M E K E RAEY L IRKQ EL T A QIN E F E NTR E vkrmety QKKK EL DK L QTKMSKIKETVTVSAAV L SDHN LE IARLHESIRY 299
Cdd:COG1196 220 EEL K E L E AELL L LKLR EL E A ELE E L E AEL E ------- ELEA EL EE L EAELAELEAELEELRLE L EELE LE LEEAQAEEYE 292
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 300 WEQ E VSE L KK D L A I LE AKLCFFTDNK E K L DD isnd E KN E FLNKIKQ L V E T L HAARM E YKDLR E KMKTLARQYKIVLSEEE 379
Cdd:COG1196 293 LLA E LAR L EQ D I A R LE ERRRELEERL E E L EE ---- E LA E LEEELEE L E E E L EELEE E LEEAE E ELEEAEAELAEAEEALL 368
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 380 K A flq KQKIHDENQKQLTFISQKEYF L SQKRVDIKNM EE GLITLQE L QQATKTVYQQQIKILS A NL E R E SQR cvitqwkm 459
Cdd:COG1196 369 E A --- EAELAEAEEELEELAEELLEA L RAAAELAAQL EE LEEAEEA L LERLERLEEELEELEE A LA E L E EEE -------- 437
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 460 aclrkkharwt AKIKAEIQAIT E KIQNA E VRRIE LL NETSFRQQ E ISGFV A QIEK L TT EL K E EEKAFVNKEKMLMKELSK 539
Cdd:COG1196 438 ----------- EEEEEALEEAA E EEAEL E EEEEA LL ELLAELLE E AALLE A ALAE L LE EL A E AAARLLLLLEAEADYEGF 506
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 767981427 540 Y E EIFVKETQINKEKEEEL V EY L PQLQV A EQEYK E KRRKLEELSNIIT DDE RRDMG I RR 598
Cdd:COG1196 507 L E GVKAALLLAGLRGLAGA V AV L IGVEA A YEAAL E AALAAALQNIVVE DDE VAAAA I EY 565
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
236-585
2.93e-06
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 50.83
E-value: 2.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 236 EL TAQ I N E F E NTREVKRMETYQKK KEL DK L QTKMSKIKETVTVSAAVL S DHNLEI ARL HESIRYW E QEVSE L K K D L AI LE 315
Cdd:TIGR02168 681 EL EEK I E E L E EKIAELEKALAELR KEL EE L EEELEQLRKELEELSRQI S ALRKDL ARL EAEVEQL E ERIAQ L S K E L TE LE 760
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 316 A KLCFFTDNK E KL ddis ND E KN E FLNK I KQ L VETLHAARM E Y K D LRE KMKT L ARQ ykiv L SEEEKAFLQKQKIHDENQKQ 395
Cdd:TIGR02168 761 A EIEELEERL E EA ---- EE E LA E AEAE I EE L EAQIEQLKE E L K A LRE ALDE L RAE ---- L TLLNEEAANLRERLESLERR 832
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 396 LTFISQKEYF L SQKRVDIKNME E G L ITLQ E LQQATKTVYQQQIKI L SA nleresqrcvitqwkmac L R KKHARWT A KIKA 475
Cdd:TIGR02168 833 IAATERRLED L EEQIEELSEDI E S L AAEI E ELEELIEELESELEA L LN ------------------ E R ASLEEAL A LLRS 894
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 476 E IQAIT E KIQNA E VR R I EL LN E TSFRQQEISGFVAQI E K L TTELKEEEKAFVNKEKMLMK E L skyeeifvketqinkek E 555
Cdd:TIGR02168 895 E LEELS E ELREL E SK R S EL RR E LEELREKLAQLELRL E G L EVRIDNLQERLSEEYSLTLE E A ----------------- E 957
330 340 350
....*....|....*....|....*....|
gi 767981427 556 EELVEYLPQLQV A EQEY K EKRR K LE EL SNI 585
Cdd:TIGR02168 958 ALENKIEDDEEE A RRRL K RLEN K IK EL GPV 987
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
201-507
3.18e-05
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 47.24
E-value: 3.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 201 K INLKREDIALQKKCIQ E A E ELM E KER AE ylir KQ EL T A QIN E FENTR E VKRM E TYQKKK E LDK L QTKMSKIKETVTVSA 280
Cdd:COG1196 233 K LRELEAELEELEAELE E L E AEL E ELE AE ---- LA EL E A ELE E LRLEL E ELEL E LEEAQA E EYE L LAELARLEQDIARLE 308
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 281 AVLSDHNLEIAR L H E SIRYW E Q E VS EL KKD L AI LE AK L cfftdnkeklddis NDEKN E FLNKIKQ L V E TLH A ARMEYKD L 360
Cdd:COG1196 309 ERRRELEERLEE L E E ELAEL E E E LE EL EEE L EE LE EE L -------------- EEAEE E LEEAEAE L A E AEE A LLEAEAE L 374
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 361 R E KMKT L ARQYKIV L SEEEK A FLQKQKIHDENQKQLTFISQK E YFLSQKRVDIKNME E GLITLQ E LQQ A TKTVYQQQIKI 440
Cdd:COG1196 375 A E AEEE L EELAEEL L EALRA A AELAAQLEELEEAEEALLERL E RLEEELEELEEALA E LEEEEE E EEE A LEEAAEEEAEL 454
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767981427 441 LSANLERESQ rcvitqwkmacl RKKHARWT A KIK A EIQAIT E KIQN A EV R RIE LL NETSFRQQEIS G 507
Cdd:COG1196 455 EEEEEALLEL ------------ LAELLEEA A LLE A ALAELL E ELAE A AA R LLL LL EAEADYEGFLE G 509
PTZ00121
PTZ00121 MAEBL; Provisional
75-592
6.12e-05
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 46.67
E-value: 6.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 75 A VA V K K L EE M RKA T i D LLEI E SMELNKLYYLL E TLPNSIKRELE E C V RD A RRLNLFEINTI K MRIT R TEN EI ELLKKKIT 154
Cdd:PTZ00121 1184 A EE V R K A EE L RKA E - D ARKA E AARKAEEERKA E EARKAEDAKKA E A V KK A EEAKKDAEEAK K AEEE R NNE EI RKFEEARM 1262
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 155 DLTKYNE A LGEKQ E ELARKHARFVLSLNQTM E - KKA TTTVYIN E TYT K INLKREDIALQ KK ciqe AEE lm E K ER A EYLIR 233
Cdd:PTZ00121 1263 AHFARRQ A AIKAE E ARKADELKKAEEKKKAD E a KKA EEKKKAD E AKK K AEEAKKADEAK KK ---- AEE -- A K KK A DAAKK 1336
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 234 K Q E LTAQIN E FENTRE --- VKRM E TYQK K K E LDKLQTKMS K I K etvtvs A AVLSDHNL E IARLH E S iryw EQEVS E L KK D 310
Cdd:PTZ00121 1337 K A E EAKKAA E AAKAEA eaa ADEA E AAEE K A E AAEKKKEEA K K K ------ A DAAKKKAE E KKKAD E A ---- KKKAE E D KK K 1406
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 311 LAI L EAK lcff TDN K E K L D DIS nd E K N E FLN K IKQLVETLHA A R m EYKDLRE K MKTLARQYKIVLSE EE KAFLQKQ K IHD 390
Cdd:PTZ00121 1407 ADE L KKA ---- AAA K K K A D EAK -- K K A E EKK K ADEAKKKAEE A K - KADEAKK K AEEAKKAEEAKKKA EE AKKADEA K KKA 1479
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 391 E NQ K QLTFISQ K EYFLSQ K RVDI K NME E GLITLQ E LQQ A TKTVYQQQI K ILSANLERESQRCVITQW K MAC L R K KH arwt 470
Cdd:PTZ00121 1480 E EA K KADEAKK K AEEAKK K ADEA K KAA E AKKKAD E AKK A EEAKKADEA K KAEEAKKADEAKKAEEKK K ADE L K K AE ---- 1555
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 471 akika E IQAIT EK IQNA E VRRI E LLNETSF R QQ E I sgf VAQI E K lt TELK E EE K AFVNKE KM LMK E LS K Y EE IFV K ETQI 550
Cdd:PTZ00121 1556 ----- E LKKAE EK KKAE E AKKA E EDKNMAL R KA E E --- AKKA E E -- ARIE E VM K LYEEEK KM KAE E AK K A EE AKI K AEEL 1625
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 767981427 551 N K EK EE - EL VE Y L PQLQVA E QEYK E KRR K L EE LSN I ITDD E RR 592
Cdd:PTZ00121 1626 K K AE EE k KK VE Q L KKKEAE E KKKA E ELK K A EE ENK I KAAE E AK 1668
CCDC158
pfam15921 Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
131-559
3.37e-03
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain]
Cd Length: 1112
Bit Score: 40.87
E-value: 3.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 131 E INTIK M RIT R T E NEIELL K kkitdltky N E AL G EKQEEL A RKHAR fvlsl N QTM EK KATT T VYINE T YTKINLKR E DIA 210
Cdd:pfam15921 420 E LDDRN M EVQ R L E ALLKAM K --------- S E CQ G QMERQM A AIQGK ----- N ESL EK VSSL T AQLES T KEMLRKVV E ELT 485
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 211 LQ K KCIQEA E E -------- L M EKERA ------------- EYLIRK QEL TAQI NE FENT R E V K ------ RMETYQ K K K ELD 263
Cdd:pfam15921 486 AK K MTLESS E R tvsdltas L Q EKERA ieatnaeitklrs RVDLKL QEL QHLK NE GDHL R N V Q teceal KLQMAE K D K VIE 565
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 264 K L QTKMSKIKET V TVSAAVLSDHNL E I A R L HES I RYWEQ E VS E L K ----- KD LA I -- LEA KLCFFTDN K E KL DD i SND E K 336
Cdd:pfam15921 566 I L RQQIENMTQL V GQHGRTAGAMQV E K A Q L EKE I NDRRL E LQ E F K ilkdk KD AK I re LEA RVSDLELE K V KL VN - AGS E R 644
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 337 NEFLNK IKQ ---- L VETLHAA R M E YKD L R E KMKT L A R QYK i VL SEE EKAFLQ K Q K IHDEN qkqltfi S Q K E yf L S Q K R VD 412
Cdd:pfam15921 645 LRAVKD IKQ erdq L LNEVKTS R N E LNS L S E DYEV L K R NFR - NK SEE METTTN K L K MQLKS ------- A Q S E -- L E Q T R NT 714
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 413 I K N ME -- E G litlqelq Q A T K TVYQQ Q IK I LSANLERES qrcvitqwkmaclrkkharwtak IKAE IQ AIT E KIQ NA EVR 490
Cdd:pfam15921 715 L K S ME gs D G -------- H A M K VAMGM Q KQ I TAKRGQIDA ----------------------- LQSK IQ FLE E AMT NA NKE 763
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767981427 491 RIE L LN E TSFRQ QE I S GFVAQIE K LTT E --- L KEE E KAFVN K EKMLMKE L S K YEEI F VKETQ I NKEK E E E L V 559
Cdd:pfam15921 764 KHF L KE E KNKLS QE L S TVATEKN K MAG E lev L RSQ E RRLKE K VANMEVA L D K ASLQ F AECQD I IQRQ E Q E S V 835
CCDC158
pfam15921 Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
292-597
3.67e-03
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain]
Cd Length: 1112
Bit Score: 40.49
E-value: 3.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 292 RL H ES IRYW E QEVSE L KKDLAI L EA KL CFFTDNKEKLD DI --- SNDEKNEFL N KIKQL V ET L H AA RMEYK D LR E KMK T LA 368
Cdd:pfam15921 93 RL N ES NELH E KQKFY L RQSVID L QT KL QEMQMERDAMA DI rrr ESQSQEDLR N QLQNT V HE L E AA KCLKE D ML E DSN T QI 172
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 369 R Q Y - K IV LS E E ------------- E K A FLQ K QKI HD e NQKQLT F I S QK --- EYF L SQKRVD I KNMEEGLITLQELQQ A T K 431
Cdd:pfam15921 173 E Q L r K MM LS H E gvlqeirsilvdf E E A SGK K IYE HD - SMSTMH F R S LG sai SKI L RELDTE I SYLKGRIFPVEDQLE A L K 251
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 432 TVY Q QQ I KI L san L ERESQ R cv I T Q wkmac L RKK H arwtaki KA EI QAI TEK IQN A ----------- E VRRIELL N ET S F 500
Cdd:pfam15921 252 SES Q NK I EL L --- L QQHQD R -- I E Q ----- L ISE H ------- EV EI TGL TEK ASS A rsqansiqsql E IIQEQAR N QN S M 314
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 501 RQQEI S GFVAQIEK L TT EL K E EEKAFVN K EKM L M K E L ---- S KYE E IFVKET Q INK E K --- EEE L VEY L PQ L QVA E Q E Y - 572
Cdd:pfam15921 315 YMRQL S DLESTVSQ L RS EL R E AKRMYED K IEE L E K Q L vlan S ELT E ARTERD Q FSQ E S gnl DDQ L QKL L AD L HKR E K E L s 394
330 340 350
....*....|....*....|....*....|
gi 767981427 573 -- KE KRRK L -- EELS N I IT D D E - RR DMGI R 597
Cdd:pfam15921 395 le KE QNKR L wd RDTG N S IT I D H l RR ELDD R 424
PRK02224
PRK02224 DNA double-strand break repair Rad50 ATPase;
205-593
4.17e-03
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain]
Cd Length: 880
Bit Score: 40.41
E-value: 4.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 205 K RE DIALQKKC I QEAE E LM --- E K ER A E YLIRKQE L TAQIN E F E NT R EVKRM E TYQKKKE ------- LDK L QTKMSKIKE 274
Cdd:PRK02224 249 R RE ELETLEAE I EDLR E TI aet E R ER E E LAEEVRD L RERLE E L E EE R DDLLA E AGLDDAD aeavear REE L EDRDEELRD 328
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 275 TVTVSAAVLSD HN L E IAR L H E SIRYW E QEVS EL KKDL A I LE AK L cff TDNK E KLD D isndekne FLNK I KQ L V E TLHAA R 354
Cdd:PRK02224 329 RLEECRVAAQA HN E E AES L R E DADDL E ERAE EL REEA A E LE SE L --- EEAR E AVE D -------- RREE I EE L E E EIEEL R 397
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 355 MEYK D LREKMKTLARQYKIVLS E eekaflqkqki H DE NQKQLT fisqkeyfls QKRVDIKNME E GLITLQE L QQ A T K --- 431
Cdd:PRK02224 398 ERFG D APVDLGNAEDFLEELRE E ----------- R DE LREREA ---------- ELEATLRTAR E RVEEAEA L LE A G K cpe 456
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 432 -------------- TVYQQQIKI L S A N LE R - E SQR cvitqwkm ACLRKKHA R WTAKIK AE -- I QAIT E KIQNA E VRRI E L 494
Cdd:PRK02224 457 cgqpvegsphveti EEDRERVEE L E A E LE D l E EEV -------- EEVEERLE R AEDLVE AE dr I ERLE E RREDL E ELIA E R 528
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 495 LNETSFRQQEISGFVAQIEK L TT E LK E EEK A FVNK E KMLMKELSKYE E IFV K ETQINKEK E -- E ELVEY L PQLQV AE Q E Y 572
Cdd:PRK02224 529 RETIEEKRERAEELRERAAE L EA E AE E KRE A AAEA E EEAEEAREEVA E LNS K LAELKERI E sl E RIRTL L AAIAD AE D E I 608
410 420
....*....|....*....|.
gi 767981427 573 KEK R R K L E E L SNI it D DERR D 593
Cdd:PRK02224 609 ERL R E K R E A L AEL -- N DERR E 627
Name
Accession
Description
Interval
E-value
SMC_prok_A
TIGR02169 chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
112-391
3.25e-08
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain]
Cd Length: 1164
Bit Score: 57.00
E-value: 3.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 112 SI KRE L E ECVRDAR - RLNLFEINT I KMRITRT E N E I E L L KKK I TD L T K YN E ALGEKQ EEL AR K - HARFVLSLNQTM EK KA 189
Cdd:TIGR02169 218 KE KRE Y E GYELLKE k EALERQKEA I ERQLASL E E E L E K L TEE I SE L E K RL E EIEQLL EEL NK K i KDLGEEEQLRVK EK IG 297
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 190 TTTVY I NETYTK I NL K ----------- REDI A LQK K CIQ E A EEL m E K E RA E YLI R KQE LT AQIN E FENTR E VK R M E TYQK 258
Cdd:TIGR02169 298 ELEAE I ASLERS I AE K ereledaeerl AKLE A EID K LLA E I EEL - E R E IE E ERK R RDK LT EEYA E LKEEL E DL R A E LEEV 376
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 259 K KE LDKLQTKMSKIK E TVTVSAAVLSDHNL E IA RL H E SIRYWEQ E VSE L KKDL A IL EAK LC - FFTDNKE K LDD I SND E K n 337
Cdd:TIGR02169 377 D KE FAETRDELKDYR E KLEKLKREINELKR E LD RL Q E ELQRLSE E LAD L NAAI A GI EAK IN e LEEEKED K ALE I KKQ E W - 455
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 767981427 338 efln K IK QL VET L HAARM E YK DL R E KMKTLARQYKIVLS E EEK A FL Q KQKIHDE 391
Cdd:TIGR02169 456 ---- K LE QL AAD L SKYEQ E LY DL K E EYDRVEKELSKLQR E LAE A EA Q ARASEER 505
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
131-447
7.91e-08
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 55.83
E-value: 7.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 131 EI NTIKMR I TRT E NE I EL L K K KITD L T K YN E A L G E KQ E E L ARKHARFVLSLNQTMEKK A TTTVYIN --- E TYTKINLKRE 207
Cdd:TIGR02168 678 EI EELEEK I EEL E EK I AE L E K ALAE L R K EL E E L E E EL E Q L RKELEELSRQISALRKDL A RLEAEVE qle E RIAQLSKELT 757
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 208 DIALQKKCIQ E AE E LM E K E R AE YLIRKQ EL T AQI NEFEN trevkrm E TYQKKKE LD K L QTKMSKIK E TVTVSAAV L SDHN 287
Cdd:TIGR02168 758 ELEAEIEELE E RL E EA E E E L AE AEAEIE EL E AQI EQLKE ------- E LKALREA LD E L RAELTLLN E EAANLRER L ESLE 830
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 288 LE IA RLHESIRYW E QEVS EL KK D LAI L E A KLCFFTDNK E K L ddis ND E KNEF LN KIKQ L V E T L HAA R M E YKD L R E KMKT L 367
Cdd:TIGR02168 831 RR IA ATERRLEDL E EQIE EL SE D IES L A A EIEELEELI E E L ---- ES E LEAL LN ERAS L E E A L ALL R S E LEE L S E ELRE L 906
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 368 ARQ yki VLSEEEKAFLQKQ K IHDENQKQLTFISQKEYFLSQKRVDIKNME E GLIT L QELQQATKTVYQQQI K I L SANLER 447
Cdd:TIGR02168 907 ESK --- RSELRRELEELRE K LAQLELRLEGLEVRIDNLQERLSEEYSLTL E EAEA L ENKIEDDEEEARRRL K R L ENKIKE 983
SMC_prok_A
TIGR02169 chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
114-418
3.93e-07
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain]
Cd Length: 1164
Bit Score: 53.53
E-value: 3.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 114 KR E LE E CV R DAR RL NLFEI -- NTIKMRIT R T EN EIEL L KKKIT D LTKYNEALGEKQ E E L ARKHARFVLS L NQTM E K katt 191
Cdd:TIGR02169 670 RS E PA E LQ R LRE RL EGLKR el SSLQSELR R I EN RLDE L SQELS D ASRKIGEIEKEI E Q L EQEEEKLKER L EELE E D ---- 745
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 192 tvyinetytkinlkredial QKKCI QE A E EL m EK E RA E YLI R KQ EL TAQINEF E nt REVKRM E TYQKKKELDKL Q TKM SK 271
Cdd:TIGR02169 746 -------------------- LSSLE QE I E NV - KS E LK E LEA R IE EL EEDLHKL E -- EALNDL E ARLSHSRIPEI Q AEL SK 802
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 272 IK E T V TVSA A V L SDHNLEIA RL HESIR Y W E Q E VS EL KKDLAI L EAKL cff TDNKEKLDDI s N DE K N E FLNKIKQ L VET L H 351
Cdd:TIGR02169 803 LE E E V SRIE A R L REIEQKLN RL TLEKE Y L E K E IQ EL QEQRID L KEQI --- KSIEKEIENL - N GK K E E LEEELEE L EAA L R 878
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767981427 352 AARMEYK DL REKMKT L AR Q YKIVLSEE E KAFL Q KQ K IHDENQKQLTFISQK E YF LS QKRVDIKNM EE 418
Cdd:TIGR02169 879 DLESRLG DL KKERDE L EA Q LRELERKI E ELEA Q IE K KRKRLSELKAKLEAL E EE LS EIEDPKGED EE 945
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
220-598
5.08e-07
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 53.02
E-value: 5.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 220 EEL M E K E RAEY L IRKQ EL T A QIN E F E NTR E vkrmety QKKK EL DK L QTKMSKIKETVTVSAAV L SDHN LE IARLHESIRY 299
Cdd:COG1196 220 EEL K E L E AELL L LKLR EL E A ELE E L E AEL E ------- ELEA EL EE L EAELAELEAELEELRLE L EELE LE LEEAQAEEYE 292
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 300 WEQ E VSE L KK D L A I LE AKLCFFTDNK E K L DD isnd E KN E FLNKIKQ L V E T L HAARM E YKDLR E KMKTLARQYKIVLSEEE 379
Cdd:COG1196 293 LLA E LAR L EQ D I A R LE ERRRELEERL E E L EE ---- E LA E LEEELEE L E E E L EELEE E LEEAE E ELEEAEAELAEAEEALL 368
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 380 K A flq KQKIHDENQKQLTFISQKEYF L SQKRVDIKNM EE GLITLQE L QQATKTVYQQQIKILS A NL E R E SQR cvitqwkm 459
Cdd:COG1196 369 E A --- EAELAEAEEELEELAEELLEA L RAAAELAAQL EE LEEAEEA L LERLERLEEELEELEE A LA E L E EEE -------- 437
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 460 aclrkkharwt AKIKAEIQAIT E KIQNA E VRRIE LL NETSFRQQ E ISGFV A QIEK L TT EL K E EEKAFVNKEKMLMKELSK 539
Cdd:COG1196 438 ----------- EEEEEALEEAA E EEAEL E EEEEA LL ELLAELLE E AALLE A ALAE L LE EL A E AAARLLLLLEAEADYEGF 506
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 767981427 540 Y E EIFVKETQINKEKEEEL V EY L PQLQV A EQEYK E KRRKLEELSNIIT DDE RRDMG I RR 598
Cdd:COG1196 507 L E GVKAALLLAGLRGLAGA V AV L IGVEA A YEAAL E AALAAALQNIVVE DDE VAAAA I EY 565
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
236-585
2.93e-06
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 50.83
E-value: 2.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 236 EL TAQ I N E F E NTREVKRMETYQKK KEL DK L QTKMSKIKETVTVSAAVL S DHNLEI ARL HESIRYW E QEVSE L K K D L AI LE 315
Cdd:TIGR02168 681 EL EEK I E E L E EKIAELEKALAELR KEL EE L EEELEQLRKELEELSRQI S ALRKDL ARL EAEVEQL E ERIAQ L S K E L TE LE 760
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 316 A KLCFFTDNK E KL ddis ND E KN E FLNK I KQ L VETLHAARM E Y K D LRE KMKT L ARQ ykiv L SEEEKAFLQKQKIHDENQKQ 395
Cdd:TIGR02168 761 A EIEELEERL E EA ---- EE E LA E AEAE I EE L EAQIEQLKE E L K A LRE ALDE L RAE ---- L TLLNEEAANLRERLESLERR 832
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 396 LTFISQKEYF L SQKRVDIKNME E G L ITLQ E LQQATKTVYQQQIKI L SA nleresqrcvitqwkmac L R KKHARWT A KIKA 475
Cdd:TIGR02168 833 IAATERRLED L EEQIEELSEDI E S L AAEI E ELEELIEELESELEA L LN ------------------ E R ASLEEAL A LLRS 894
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 476 E IQAIT E KIQNA E VR R I EL LN E TSFRQQEISGFVAQI E K L TTELKEEEKAFVNKEKMLMK E L skyeeifvketqinkek E 555
Cdd:TIGR02168 895 E LEELS E ELREL E SK R S EL RR E LEELREKLAQLELRL E G L EVRIDNLQERLSEEYSLTLE E A ----------------- E 957
330 340 350
....*....|....*....|....*....|
gi 767981427 556 EELVEYLPQLQV A EQEY K EKRR K LE EL SNI 585
Cdd:TIGR02168 958 ALENKIEDDEEE A RRRL K RLEN K IK EL GPV 987
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
82-380
1.71e-05
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 48.13
E-value: 1.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 82 E E M R KATID LL EIESM EL NKL yyl LE T L PNSI K REL EE CVRDARR L NLF E I ntikm RITRTEN E IEL L KKK I TD L T K YNE 161
Cdd:TIGR02168 220 A E L R ELELA LL VLRLE EL REE --- LE E L QEEL K EAE EE LEELTAE L QEL E E ----- KLEELRL E VSE L EEE I EE L Q K ELY 291
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 162 AL GEKQEE L ARKHARFVLS L NQTMEKKATTTVYIN E TYT K INLKR E DI A LQKKCIQ E AE E LM E KER AE Y lirk Q EL T A QI 241
Cdd:TIGR02168 292 AL ANEISR L EQQKQILRER L ANLERQLEELEAQLE E LES K LDELA E EL A ELEEKLE E LK E EL E SLE AE L ---- E EL E A EL 367
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 242 N E F E NTR E VKRMETYQKKKELDK L QTKMSKIKETVTVSA A V L SDHNLEIA RL HES I RYWEQE ------------ VS EL KK 309
Cdd:TIGR02168 368 E E L E SRL E ELEEQLETLRSKVAQ L ELQIASLNNEIERLE A R L ERLEDRRE RL QQE I EELLKK leeaelkelqae LE EL EE 447
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767981427 310 D L AI L EAK L CFFTDNK E K L DD i SND E KNEF L NKIKQLVET L H A ARMEYKD L R E KMKTLARQY K IV L SEEEK 380
Cdd:TIGR02168 448 E L EE L QEE L ERLEEAL E E L RE - ELE E AEQA L DAAERELAQ L Q A RLDSLER L Q E NLEGFSEGV K AL L KNQSG 517
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
217-456
2.41e-05
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 47.74
E-value: 2.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 217 QE AEELM E K E RA E YLIRK QEL TAQIN E FENTREVKRM E TYQKK KEL DK L QTKM S KIKETVTVSAAV L SDHNLEIAR L HES 296
Cdd:TIGR02168 245 QE ELKEA E E E LE E LTAEL QEL EEKLE E LRLEVSELEE E IEELQ KEL YA L ANEI S RLEQQKQILRER L ANLERQLEE L EAQ 324
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 297 IRYW E QEVS EL KKD LA I LE A KL CFFTDNK E K L D --- DISND E KN E FLNKIKQ L V E T L HAA R MEYKD L REKMKT L ARQYKI 373
Cdd:TIGR02168 325 LEEL E SKLD EL AEE LA E LE E KL EELKEEL E S L E ael EELEA E LE E LESRLEE L E E Q L ETL R SKVAQ L ELQIAS L NNEIER 404
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 374 VLSEE E KAFLQKQKIHD E NQKQ L TFISQK E YFLS Q KRVDIKNM E -------- E G L ITLQ E LQQATKTVYQ Q QIKILSAN L 445
Cdd:TIGR02168 405 LEARL E RLEDRRERLQQ E IEEL L KKLEEA E LKEL Q AELEELEE E leelqeel E R L EEAL E ELREELEEAE Q ALDAAERE L 484
250
....*....|.
gi 767981427 446 ERESQ R CVITQ 456
Cdd:TIGR02168 485 AQLQA R LDSLE 495
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
201-507
3.18e-05
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 47.24
E-value: 3.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 201 K INLKREDIALQKKCIQ E A E ELM E KER AE ylir KQ EL T A QIN E FENTR E VKRM E TYQKKK E LDK L QTKMSKIKETVTVSA 280
Cdd:COG1196 233 K LRELEAELEELEAELE E L E AEL E ELE AE ---- LA EL E A ELE E LRLEL E ELEL E LEEAQA E EYE L LAELARLEQDIARLE 308
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 281 AVLSDHNLEIAR L H E SIRYW E Q E VS EL KKD L AI LE AK L cfftdnkeklddis NDEKN E FLNKIKQ L V E TLH A ARMEYKD L 360
Cdd:COG1196 309 ERRRELEERLEE L E E ELAEL E E E LE EL EEE L EE LE EE L -------------- EEAEE E LEEAEAE L A E AEE A LLEAEAE L 374
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 361 R E KMKT L ARQYKIV L SEEEK A FLQKQKIHDENQKQLTFISQK E YFLSQKRVDIKNME E GLITLQ E LQQ A TKTVYQQQIKI 440
Cdd:COG1196 375 A E AEEE L EELAEEL L EALRA A AELAAQLEELEEAEEALLERL E RLEEELEELEEALA E LEEEEE E EEE A LEEAAEEEAEL 454
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767981427 441 LSANLERESQ rcvitqwkmacl RKKHARWT A KIK A EIQAIT E KIQN A EV R RIE LL NETSFRQQEIS G 507
Cdd:COG1196 455 EEEEEALLEL ------------ LAELLEEA A LLE A ALAELL E ELAE A AA R LLL LL EAEADYEGFLE G 509
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
301-584
3.22e-05
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 47.36
E-value: 3.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 301 EQ E VS EL KKDLAI LE A K L cfftdnkekld DISNDEKN E FLNKIKQ L V E T L HAA R M E YKD L REKMKT L ARQYKIVLS E E E K 380
Cdd:TIGR02168 676 RR E IE EL EEKIEE LE E K I ----------- AELEKALA E LRKELEE L E E E L EQL R K E LEE L SRQISA L RKDLARLEA E V E Q 744
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 381 AFLQKQKIHD E NQKQLTF I SQK E YF L SQKRVDIKNM E EGLIT L QELQQAT K TVYQQQIKI L SA n L ER E SQRCVITQWKMA 460
Cdd:TIGR02168 745 LEERIAQLSK E LTELEAE I EEL E ER L EEAEEELAEA E AEIEE L EAQIEQL K EELKALREA L DE - L RA E LTLLNEEAANLR 823
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 461 CLRKKHA R WT A KIKAEIQAIT E K I QNAEVRRIE L lnetsfr QQ EI SGFVAQ IE K L TT EL KEEEKAFVNK E KM L MKEL S KY 540
Cdd:TIGR02168 824 ERLESLE R RI A ATERRLEDLE E Q I EELSEDIES L ------- AA EI EELEEL IE E L ES EL EALLNERASL E EA L ALLR S EL 896
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 767981427 541 E eifvketqink E KE EEL V E YLPQLQVAEQ E YK E K R R KL EE L SN 584
Cdd:TIGR02168 897 E ----------- E LS EEL R E LESKRSELRR E LE E L R E KL AQ L EL 929
SMC_prok_A
TIGR02169 chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
228-583
5.69e-05
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain]
Cd Length: 1164
Bit Score: 46.60
E-value: 5.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 228 AEYLIRK Q E L TAQINEFENTREVKRM E TYQKKKE LD K L QTKM S kiketvt VSAAVLSDHNL EI AR L HESIRYWEQEVS EL 307
Cdd:TIGR02169 670 RSEPAEL Q R L RERLEGLKRELSSLQS E LRRIENR LD E L SQEL S ------- DASRKIGEIEK EI EQ L EQEEEKLKERLE EL 742
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 308 KK DL AI LE AKL cff TDN K EK L DDISND ekneflnk I KQ L V E T LH AARMEYK DL REKM ktla RQYK I VLSEE E KAF L QKQ k 387
Cdd:TIGR02169 743 EE DL SS LE QEI --- ENV K SE L KELEAR -------- I EE L E E D LH KLEEALN DL EARL ---- SHSR I PEIQA E LSK L EEE - 806
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 388 i HDENQKQ L TF I S QK EYF L SQKRVDIKNMEEG L ITLQELQQATKTVYQQQ I KI L SANL E RESQRCVITQWKMAC L RKKHA 467
Cdd:TIGR02169 807 - VSRIEAR L RE I E QK LNR L TLEKEYLEKEIQE L QEQRIDLKEQIKSIEKE I EN L NGKK E ELEEELEELEAALRD L ESRLG 885
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 468 rwta KI K A E IQAITEKIQNA E VRRI EL LNETSFRQQEI S GFV A QI E K L TT EL K E E E K afvnk E K MLMK E LSKY E EIFVKE 547
Cdd:TIGR02169 886 ---- DL K K E RDELEAQLREL E RKIE EL EAQIEKKRKRL S ELK A KL E A L EE EL S E I E D ----- P K GEDE E IPEE E LSLEDV 956
330 340 350
....*....|....*....|....*....|....*.
gi 767981427 548 TQINKEK EEE LVEYL P QLQV A E QEY K E KRRK L E EL S 583
Cdd:TIGR02169 957 QAELQRV EEE IRALE P VNML A I QEY E E VLKR L D EL K 992
PTZ00121
PTZ00121 MAEBL; Provisional
75-592
6.12e-05
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 46.67
E-value: 6.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 75 A VA V K K L EE M RKA T i D LLEI E SMELNKLYYLL E TLPNSIKRELE E C V RD A RRLNLFEINTI K MRIT R TEN EI ELLKKKIT 154
Cdd:PTZ00121 1184 A EE V R K A EE L RKA E - D ARKA E AARKAEEERKA E EARKAEDAKKA E A V KK A EEAKKDAEEAK K AEEE R NNE EI RKFEEARM 1262
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 155 DLTKYNE A LGEKQ E ELARKHARFVLSLNQTM E - KKA TTTVYIN E TYT K INLKREDIALQ KK ciqe AEE lm E K ER A EYLIR 233
Cdd:PTZ00121 1263 AHFARRQ A AIKAE E ARKADELKKAEEKKKAD E a KKA EEKKKAD E AKK K AEEAKKADEAK KK ---- AEE -- A K KK A DAAKK 1336
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 234 K Q E LTAQIN E FENTRE --- VKRM E TYQK K K E LDKLQTKMS K I K etvtvs A AVLSDHNL E IARLH E S iryw EQEVS E L KK D 310
Cdd:PTZ00121 1337 K A E EAKKAA E AAKAEA eaa ADEA E AAEE K A E AAEKKKEEA K K K ------ A DAAKKKAE E KKKAD E A ---- KKKAE E D KK K 1406
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 311 LAI L EAK lcff TDN K E K L D DIS nd E K N E FLN K IKQLVETLHA A R m EYKDLRE K MKTLARQYKIVLSE EE KAFLQKQ K IHD 390
Cdd:PTZ00121 1407 ADE L KKA ---- AAA K K K A D EAK -- K K A E EKK K ADEAKKKAEE A K - KADEAKK K AEEAKKAEEAKKKA EE AKKADEA K KKA 1479
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 391 E NQ K QLTFISQ K EYFLSQ K RVDI K NME E GLITLQ E LQQ A TKTVYQQQI K ILSANLERESQRCVITQW K MAC L R K KH arwt 470
Cdd:PTZ00121 1480 E EA K KADEAKK K AEEAKK K ADEA K KAA E AKKKAD E AKK A EEAKKADEA K KAEEAKKADEAKKAEEKK K ADE L K K AE ---- 1555
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 471 akika E IQAIT EK IQNA E VRRI E LLNETSF R QQ E I sgf VAQI E K lt TELK E EE K AFVNKE KM LMK E LS K Y EE IFV K ETQI 550
Cdd:PTZ00121 1556 ----- E LKKAE EK KKAE E AKKA E EDKNMAL R KA E E --- AKKA E E -- ARIE E VM K LYEEEK KM KAE E AK K A EE AKI K AEEL 1625
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 767981427 551 N K EK EE - EL VE Y L PQLQVA E QEYK E KRR K L EE LSN I ITDD E RR 592
Cdd:PTZ00121 1626 K K AE EE k KK VE Q L KKKEAE E KKKA E ELK K A EE ENK I KAAE E AK 1668
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
64-592
1.94e-04
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 44.54
E-value: 1.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 64 NE E AKIFLKDI A VAVKK LEE M R KA t IDL LE I E SM E LNKLY Y L L E tlpnsik R EL EECVR D AR RL NL f EINTIKM R ITRT E 143
Cdd:COG1196 252 EA E LEELEAEL A ELEAE LEE L R LE - LEE LE L E LE E AQAEE Y E L L ------- A EL ARLEQ D IA RL EE - RRRELEE R LEEL E 322
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 144 N E IEL L KKKITD L TKYN E A L G E KQ EE LARKHARFVLS L NQTM E K - KATTTVYINETYTKIN L KR E DIALQKKCIQE A EE L 222
Cdd:COG1196 323 E E LAE L EEELEE L EEEL E E L E E EL EE AEEELEEAEAE L AEAE E A l LEAEAELAEAEEELEE L AE E LLEALRAAAEL A AQ L 402
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 223 M E K E R AE -- Y L I R KQE L TAQIN E F E NTREVKRM E TYQKKKE L DKLQTKMSKIK E TVTVSAAV L SDHNL E I A R L HESIRYW 300
Cdd:COG1196 403 E E L E E AE ea L L E R LER L EEELE E L E EALAELEE E EEEEEEA L EEAAEEEAELE E EEEALLEL L AELLE E A A L L EAALAEL 482
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 301 EQ E VS E LKKD L AI L EAKL cff T D NKEK L DDISNDEKNEF L NKIKQL V ET L HAARME Y KDLR E KMKTL A R Q Y k IV LSEE E K 380
Cdd:COG1196 483 LE E LA E AAAR L LL L LEAE --- A D YEGF L EGVKAALLLAG L RGLAGA V AV L IGVEAA Y EAAL E AALAA A L Q N - IV VEDD E V 558
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 381 A FLQKQKIHDENQKQL TF I --- SQKEYFLSQKRVDIKNMEEGLITLQELQQATKTV Y QQQIKI L SANLE resqrc V ITQW 457
Cdd:COG1196 559 A AAAIEYLKAAKAGRA TF L pld KIRARAALAAALARGAIGAAVDLVASDLREADAR Y YVLGDT L LGRTL ------ V AARL 632
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 458 KM A CL R KKHARWTAKIK - A E IQAITEKIQNAEVR R I ELL NETSFRQQ E ISGFVAQIEKLTT E ------- LK EEE KAFVNK 529
Cdd:COG1196 633 EA A LR R AVTLAGRLREV t L E GEGGSAGGSLTGGS R R ELL AALLEAEA E LEELAERLAEEEL E leealla EE EEE RELAEA 712
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767981427 530 E KMLMK E LSKY E EIFVKETQINK E KE EEL V E YLPQ L QVAEQ E YKEKRRK LEEL SNIITDD ER R 592
Cdd:COG1196 713 E EERLE E ELEE E ALEEQLEAERE E LL EEL L E EEEL L EEEAL E ELPEPPD LEEL ERELERL ER E 775
PRK03918
PRK03918 DNA double-strand break repair ATPase Rad50;
79-606
6.76e-04
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain]
Cd Length: 880
Bit Score: 42.74
E-value: 6.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 79 KKLEEM RK ATIDLL E I E SM e LNK L YYLL E T L PNSI K R -- EL E E CVRDARR L NL F ------ E INT I KM R IT R T E N EI ELLK 150
Cdd:PRK03918 249 SLEGSK RK LEEKIR E L E ER - IEE L KKEI E E L EEKV K E lk EL K E KAEEYIK L SE F yeeyld E LRE I EK R LS R L E E EI NGIE 327
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 151 KK I TD L TKYN E A L G E --- K QE EL ARKHARF vlslnqtm E KKA tttvyin E T Y TKINL K R E DI - A L Q K KCIQEAE E LM EKE 226
Cdd:PRK03918 328 ER I KE L EEKE E R L E E lkk K LK EL EKRLEEL -------- E ERH ------- E L Y EEAKA K K E EL e R L K K RLTGLTP E KL EKE 392
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 227 RA E YLIR K Q E LTAQ I NEFEN trev KRM E TYQKK KEL D K LQTKMS K I K ETVT V SAAV L SDHN --------- L E IA R LHESI 297
Cdd:PRK03918 393 LE E LEKA K E E IEEE I SKITA ---- RIG E LKKEI KEL K K AIEELK K A K GKCP V CGRE L TEEH rkelleeyt A E LK R IEKEL 468
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 298 RYW E QEVSE L K K D L AI LE AK L CF --- FTDN KE KLDDISND E kn E F L N K IK ql V E T L HAARM EY KD L R EK MKT L ARQY K IV 374
Cdd:PRK03918 469 KEI E EKERK L R K E L RE LE KV L KK ese LIKL KE LAEQLKEL E -- E K L K K YN -- L E E L EKKAE EY EK L K EK LIK L KGEI K SL 544
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 375 LS E - E EKAF L Q K QKIHD E NQKQLTFISQK E YFLSQKRVDIKNM EE GLIT L Q EL QQA tktv Y QQQIKILS A nleresqrcv 453
Cdd:PRK03918 545 KK E l E KLEE L K K KLAEL E KKLDELEEELA E LLKELEELGFESV EE LEER L K EL EPF ---- Y NEYLELKD A ---------- 610
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 454 itqwkmaclrkkharwtaki KA E IQAITEKIQNA E vrriell N E TSFRQQ E ISGFVAQI E K L TT EL K E E EK AFVNK E -- K 531
Cdd:PRK03918 611 -------------------- EK E LEREEKELKKL E ------- E E LDKAFE E LAETEKRL E E L RK EL E E L EK KYSEE E ye E 663
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767981427 532 MLMKE L SKYE E IFVKETQI -- NKEKE EE LVEY L PQ L QVAEQ E YKEKRRK LE E L SNIITDD E RRDMGIRRPGPKVT ER 606
Cdd:PRK03918 664 LREEY L ELSR E LAGLRAEL ee LEKRR EE IKKT L EK L KEELE E REKAKKE LE K L EKALERV E ELREKVKKYKALLK ER 740
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
66-571
6.76e-04
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 43.00
E-value: 6.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 66 EA KIF L KDIAVAVKK LEE MR k A TIDL LE I E SM EL NKLYYL LE TLPNSIKR ELEE CVRDARRLNL f E INTIKMRIT R T E NE 145
Cdd:COG1196 226 EA ELL L LKLRELEAE LEE LE - A ELEE LE A E LE EL EAELAE LE AELEELRL ELEE LELELEEAQA - E EYELLAELA R L E QD 303
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 146 I EL L KKKITD L TKYN E A L G E KQE EL ARKHARFVLS L NQTM E KKATTT -------- VYINETYTKINLKR E DIALQKKCIQ 217
Cdd:COG1196 304 I AR L EERRRE L EERL E E L E E ELA EL EEELEELEEE L EELE E ELEEAE eeleeaea ELAEAEEALLEAEA E LAEAEEELEE 383
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 218 E AEEL M E KE RA EYLIRK Q ELTAQIN E FENTREVK R M E TYQK --------- KK E LDKLQTKMSKIK E TVTVSAAVLSDHNL 288
Cdd:COG1196 384 L AEEL L E AL RA AAELAA Q LEELEEA E EALLERLE R L E EELE eleealael EE E EEEEEEALEEAA E EEAELEEEEEALLE 463
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 289 EI A R L H E SIRYW E QEVS EL KKD LA ILE A K L CFFTDNKEKLDDISNDE K NEF L NKIKQLVETLH A ARM ---- E Y KDLR E KM 364
Cdd:COG1196 464 LL A E L L E EAALL E AALA EL LEE LA EAA A R L LLLLEAEADYEGFLEGV K AAL L LAGLRGLAGAV A VLI gvea A Y EAAL E AA 543
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 365 KTL A R Q Y k IV LSEE E K A FLQKQKIHDENQKQL TF I --- SQKEYFLSQKRVDIKNMEEGLITLQELQQATKTV Y QQQIKI L 441
Cdd:COG1196 544 LAA A L Q N - IV VEDD E V A AAAIEYLKAAKAGRA TF L pld KIRARAALAAALARGAIGAAVDLVASDLREADAR Y YVLGDT L 622
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 442 SANLE resqrc V ITQWKM A CL R KKHARWTAKIK - A E IQAITEKIQNAEVR R I ELL NETSFRQQ E ISGFVAQIEKLTT EL K 520
Cdd:COG1196 623 LGRTL ------ V AARLEA A LR R AVTLAGRLREV t L E GEGGSAGGSLTGGS R R ELL AALLEAEA E LEELAERLAEEEL EL E 696
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|.
gi 767981427 521 E EEK A FVNK E KM L MKELSKYE E IFVK E TQINKEK E E E LV E Y L PQ L QVA E QE 571
Cdd:COG1196 697 E ALL A EEEE E RE L AEAEEERL E EELE E EALEEQL E A E RE E L L EE L LEE E EL 747
PRK03918
PRK03918 DNA double-strand break repair ATPase Rad50;
79-592
1.08e-03
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain]
Cd Length: 880
Bit Score: 42.36
E-value: 1.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 79 KK L E E MRKATID L L E IES m EL N KL YYLLET L p NSI K R E L EE CVRDARR L NL f EINTIKMR I TRT E NE IE L LKK K I TD L TK 158
Cdd:PRK03918 204 EV L R E INEISSE L P E LRE - EL E KL EKEVKE L - EEL K E E I EE LEKELES L EG - SKRKLEEK I REL E ER IE E LKK E I EE L EE 280
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 159 YNEA L g EKQE E L A RKHARFVLSLNQTMEKKATTTVYINETYTK IN LKR E D I ALQKKCIQEA EEL m E K ERA E YLI R KQ EL T 238
Cdd:PRK03918 281 KVKE L - KELK E K A EEYIKLSEFYEEYLDELREIEKRLSRLEEE IN GIE E R I KELEEKEERL EEL - K K KLK E LEK R LE EL E 358
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 239 AQINEF E NTREV K - RM E TYQ K KK ------ E L D K LQTKMS K I KE TVT vsaavlsdhn L EI ARLHES I RYWEQ E VS ELKK DL 311
Cdd:PRK03918 359 ERHELY E EAKAK K e EL E RLK K RL tgltpe K L E K ELEELE K A KE EIE ---------- E EI SKITAR I GELKK E IK ELKK AI 428
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 312 AI L E - AK LCFFTDNK E kldd ISNDEKN E F L NKIKQLVETLHAARM E YKDLRE K MKTLA R QYKI VL SE E EKAFLQ K Q -- KI 388
Cdd:PRK03918 429 EE L K k AK GKCPVCGR E ---- LTEEHRK E L L EEYTAELKRIEKELK E IEEKER K LRKEL R ELEK VL KK E SELIKL K E la EQ 504
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 389 HD E NQKQ L TFISQK E yf L SQ K RVDIKNME E G LI T L Q elqqatktvyq QQ IK I L SAN LE RE sqrcvitqwkmaclrkkhar 468
Cdd:PRK03918 505 LK E LEEK L KKYNLE E -- L EK K AEEYEKLK E K LI K L K ----------- GE IK S L KKE LE KL -------------------- 551
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 469 wt AKI K AEIQAITE K IQNA E VRRI ELL N E TSFR qqeis GF v AQI E K L TTE LKE E E KAF vn K E KMLM K ELS K YE E IFV KE T 548
Cdd:PRK03918 552 -- EEL K KKLAELEK K LDEL E EELA ELL K E LEEL ----- GF - ESV E E L EER LKE L E PFY -- N E YLEL K DAE K EL E REE KE L 621
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 767981427 549 qin K EK EEEL VEYLPQ L QVA E QEYK E K R RK LEEL SNIITDD E RR 592
Cdd:PRK03918 622 --- K KL EEEL DKAFEE L AET E KRLE E L R KE LEEL EKKYSEE E YE 662
PTZ00121
PTZ00121 MAEBL; Provisional
53-605
1.79e-03
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 41.67
E-value: 1.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 53 E QSLQSDYFKCN EEA KIFLKDIAV A VK K L EE M RKA T idll E IESM E LN K ly YLL E TLPNSI K RELE E CVRD A RRLN lf EI 132
Cdd:PTZ00121 1246 E EERNNEEIRKF EEA RMAHFARRQ A AI K A EE A RKA D ---- E LKKA E EK K -- KAD E AKKAEE K KKAD E AKKK A EEAK -- KA 1317
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 133 NTI K MRITRTENEIELL KKK ITDLT K YN EA LGEKQ E EL A RKHARFVLSLNQTME KK ATTTVYINETYT K INL K REDIALQ 212
Cdd:PTZ00121 1318 DEA K KKAEEAKKKADAA KKK AEEAK K AA EA AKAEA E AA A DEAEAAEEKAEAAEK KK EEAKKKADAAKK K AEE K KKADEAK 1397
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 213 KK CIQE --- A E EL M ---- E K ER A EYLIR K Q E LTAQIN E FENTR E VKRMETYQ KKK ELDKLQTKMS K I K ETVTVS A AVLSD 285
Cdd:PTZ00121 1398 KK AEED kkk A D EL K kaaa A K KK A DEAKK K A E EKKKAD E AKKKA E EAKKADEA KKK AEEAKKAEEA K K K AEEAKK A DEAKK 1477
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 286 HNL E IARLH E S iryw EQEVS E L KK DLAILEAK lcff TDN K E K L D DISND E KNEFLNKI K QLV E TLH A ARMEYKDLRE K MK 365
Cdd:PTZ00121 1478 KAE E AKKAD E A ---- KKKAE E A KK KADEAKKA ---- AEA K K K A D EAKKA E EAKKADEA K KAE E AKK A DEAKKAEEKK K AD 1549
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 366 T L ARQYKIVLS EE E K AFLQKQ K IHDENQKQ L tfisqkeyfls Q K RVDI K NM EE GL I T - LQE L QQAT K TVYQQQI K ilsan 444
Cdd:PTZ00121 1550 E L KKAEELKKA EE K K KAEEAK K AEEDKNMA L ----------- R K AEEA K KA EE AR I E e VMK L YEEE K KMKAEEA K ----- 1613
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 445 l ER E SQRCVITQW K M A CLR KK HARWTA K IK AE IQAIT E KIQN AE VRRIELLN E TSFRQQ E ISGFVAQIE K LTTEL K EEEK 524
Cdd:PTZ00121 1614 - KA E EAKIKAEEL K K A EEE KK KVEQLK K KE AE EKKKA E ELKK AE EENKIKAA E EAKKAE E DKKKAEEAK K AEEDE K KAAE 1692
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 525 A FVNK -- E KMLMK EL S K Y E EIFV K ETQIN K EK EEE LVEYLPQLQVAEQ E Y K E K RRKLE ------- ELSNIITDD E RRDMG 595
Cdd:PTZ00121 1693 A LKKE ae E AKKAE EL K K K E AEEK K KAEEL K KA EEE NKIKAEEAKKEAE E D K K K AEEAK kdeeekk KIAHLKKEE E KKAEE 1772
570
....*....|
gi 767981427 596 IR RPGPK V T E 605
Cdd:PTZ00121 1773 IR KEKEA V I E 1782
EnvC
COG4942 Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
111-328
2.00e-03
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain]
Cd Length: 377
Bit Score: 40.90
E-value: 2.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 111 NSI K R E LEECVRDARR L NL f E I NTIKM RI TRT E N E IEL L KKKITD L T K YNEA L GEKQ E ELARKH A RFVLS L NQTM ekkat 190
Cdd:COG4942 44 AAL K K E EKALLKQLAA L ER - R I AALAR RI RAL E Q E LAA L EAELAE L E K EIAE L RAEL E AQKEEL A ELLRA L YRLG ----- 117
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 191 ttvyi NETYTKIN L KR ED IALQKKCI Q EAEE L ME -- K E R AE Y L IRKQ - EL T A QIN E F E NT R EVKRMETYQKKK E LDK L QT 267
Cdd:COG4942 118 ----- RQPPLALL L SP ED FLDAVRRL Q YLKY L AP ar R E Q AE E L RADL a EL A A LRA E L E AE R AELEALLAELEE E RAA L EA 192
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767981427 268 KMSKIKETVTVSAAV L SDHNL E I A R L HESIRYW E QEVSE L KKDL A ILEAKLCF -- F TDN K E KL 328
Cdd:COG4942 193 LKAERQKLLARLEKE L AELAA E L A E L QQEAEEL E ALIAR L EAEA A AAAERTPA ag F AAL K G KL 255
EnvC
COG4942 Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
233-451
2.26e-03
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain]
Cd Length: 377
Bit Score: 40.90
E-value: 2.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 233 RKQE L TAQ I N E F E NTREVKRM E TYQKK K E L DK L QTKMSKIKETVTVSAAV L SDHNL E I A R L HES I RYWEQ E VSEL K KD LA 312
Cdd:COG4942 28 ELEQ L QQE I A E L E KELAALKK E EKALL K Q L AA L ERRIAALARRIRALEQE L AALEA E L A E L EKE I AELRA E LEAQ K EE LA 107
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 313 I L EAK L CFFTDNKEKLDDI S NDEKNEFLNKIKQ L VETLH A A R MEYKD LR EKMKT LA RQYKIVLS E EEKAFLQKQKIHD E N 392
Cdd:COG4942 108 E L LRA L YRLGRQPPLALLL S PEDFLDAVRRLQY L KYLAP A R R EQAEE LR ADLAE LA ALRAELEA E RAELEALLAELEE E R 187
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 767981427 393 QKQLTFISQKEYF L SQKRVDIKNMEE gli T L Q ELQQ ATKT v YQQQ I KI L S A NLERESQ R 451
Cdd:COG4942 188 AALEALKAERQKL L ARLEKELAELAA --- E L A ELQQ EAEE - LEAL I AR L E A EAAAAAE R 242
Mplasa_alph_rch
TIGR04523 helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
78-448
2.70e-03
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain]
Cd Length: 745
Bit Score: 40.77
E-value: 2.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 78 VKK L EEMRKATI D LL E IESM E L N KLYYLLETLPNSIKRELE E CVRDARR L N -- LF E INTIKMR I TRT E NEIEL LK KK I T D 155
Cdd:TIGR04523 220 ISE L KKQNNQLK D NI E KKQQ E I N EKTTEISNTQTQLNQLKD E QNKIKKQ L S ek QK E LEQNNKK I KEL E KQLNQ LK SE I S D 299
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 156 L TK ynealg E K QEELARKHARF vls L NQTME K KATTTVY I NETYTK I NLKR E D I ALQ KK CIQEA E --------------- 220
Cdd:TIGR04523 300 L NN ------ Q K EQDWNKELKSE --- L KNQEK K LEEIQNQ I SQNNKI I SQLN E Q I SQL KK ELTNS E sensekqreleekqn 370
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 221 -- E LME KE RAE Y LIRKQE L TA QIN EF E NTREVKRMETY QK KKELD KLQ TKMSKIKE tvtvsaavlsdhnl EI A RL H E S I R 298
Cdd:TIGR04523 371 ei E KLK KE NQS Y KQEIKN L ES QIN DL E SKIQNQEKLNQ QK DEQIK KLQ QEKELLEK -------------- EI E RL K E T I I 436
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 299 YWEQ E VSE L KKDLAIL E AKL cfft D N KEKLDDISNDEKNEFLNK I KQLVET L HAARM E Y K DLREKM K T L ARQ y K IV L S E E 378
Cdd:TIGR04523 437 KNNS E IKD L TNQDSVK E LII ---- K N LDNTRESLETQLKVLSRS I NKIKQN L EQKQK E L K SKEKEL K K L NEE - K KE L E E K 511
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767981427 379 E K AFLQ K QKIHD E NQKQ L TF - ISQ KE YFL S QKRVDIKNMEEG L ------ ITLQ E LQQATKTVY Q Q Q IKILSANL E RE 448
Cdd:TIGR04523 512 V K DLTK K ISSLK E KIEK L ES e KKE KE SKI S DLEDELNKDDFE L kkenle KEID E KNKEIEELK Q T Q KSLKKKQE E KQ 588
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
368-593
2.96e-03
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 40.69
E-value: 2.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 368 A RQ Y K i V L S EE E K AFLQKQKIHDENQKQLTFISQKE yflsq KRVDIKNME E G L ITLQELQQ A TKTVYQQQIKI L SAN LE R 447
Cdd:COG1196 212 A ER Y R - E L K EE L K ELEAELLLLKLRELEAELEELEA ----- ELEELEAEL E E L EAELAELE A ELEELRLELEE L ELE LE E 285
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 448 ESQR cvitqwkmac LRKKH A R w T A KIKAE I QAIT E KIQNA E V R RI EL lnetsfr QQ E ISGFVAQI E K L TT EL K E E E KAFV 527
Cdd:COG1196 286 AQAE ---------- EYELL A E - L A RLEQD I ARLE E RRREL E E R LE EL ------- EE E LAELEEEL E E L EE EL E E L E EELE 347
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767981427 528 NK E K --- MLMK EL SKY EE IFVKETQINK E K EEEL V E YLPQ L QV A EQEYK E KRRK LEEL SNIITDDER R D 593
Cdd:COG1196 348 EA E E ele EAEA EL AEA EE ALLEAEAELA E A EEEL E E LAEE L LE A LRAAA E LAAQ LEEL EEAEEALLE R L 416
CCDC158
pfam15921 Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
131-559
3.37e-03
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain]
Cd Length: 1112
Bit Score: 40.87
E-value: 3.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 131 E INTIK M RIT R T E NEIELL K kkitdltky N E AL G EKQEEL A RKHAR fvlsl N QTM EK KATT T VYINE T YTKINLKR E DIA 210
Cdd:pfam15921 420 E LDDRN M EVQ R L E ALLKAM K --------- S E CQ G QMERQM A AIQGK ----- N ESL EK VSSL T AQLES T KEMLRKVV E ELT 485
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 211 LQ K KCIQEA E E -------- L M EKERA ------------- EYLIRK QEL TAQI NE FENT R E V K ------ RMETYQ K K K ELD 263
Cdd:pfam15921 486 AK K MTLESS E R tvsdltas L Q EKERA ieatnaeitklrs RVDLKL QEL QHLK NE GDHL R N V Q teceal KLQMAE K D K VIE 565
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 264 K L QTKMSKIKET V TVSAAVLSDHNL E I A R L HES I RYWEQ E VS E L K ----- KD LA I -- LEA KLCFFTDN K E KL DD i SND E K 336
Cdd:pfam15921 566 I L RQQIENMTQL V GQHGRTAGAMQV E K A Q L EKE I NDRRL E LQ E F K ilkdk KD AK I re LEA RVSDLELE K V KL VN - AGS E R 644
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 337 NEFLNK IKQ ---- L VETLHAA R M E YKD L R E KMKT L A R QYK i VL SEE EKAFLQ K Q K IHDEN qkqltfi S Q K E yf L S Q K R VD 412
Cdd:pfam15921 645 LRAVKD IKQ erdq L LNEVKTS R N E LNS L S E DYEV L K R NFR - NK SEE METTTN K L K MQLKS ------- A Q S E -- L E Q T R NT 714
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 413 I K N ME -- E G litlqelq Q A T K TVYQQ Q IK I LSANLERES qrcvitqwkmaclrkkharwtak IKAE IQ AIT E KIQ NA EVR 490
Cdd:pfam15921 715 L K S ME gs D G -------- H A M K VAMGM Q KQ I TAKRGQIDA ----------------------- LQSK IQ FLE E AMT NA NKE 763
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767981427 491 RIE L LN E TSFRQ QE I S GFVAQIE K LTT E --- L KEE E KAFVN K EKMLMKE L S K YEEI F VKETQ I NKEK E E E L V 559
Cdd:pfam15921 764 KHF L KE E KNKLS QE L S TVATEKN K MAG E lev L RSQ E RRLKE K VANMEVA L D K ASLQ F AECQD I IQRQ E Q E S V 835
SMC_prok_A
TIGR02169 chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
72-593
3.55e-03
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain]
Cd Length: 1164
Bit Score: 40.82
E-value: 3.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 72 K DIAVAVKK LEE MR K ATI DL L E I E SMELNKLYYL LE TLPN S IK R ELE E CV R DARRLNL f EINTIKMR I TRTEN EIE L L KK 151
Cdd:TIGR02169 265 K RLEEIEQL LEE LN K KIK DL G E E E QLRVKEKIGE LE AEIA S LE R SIA E KE R ELEDAEE - RLAKLEAE I DKLLA EIE E L ER 343
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 152 K I TDLT K YNEA L G E KQE EL ARKHARFVLS L NQTMEKK A T T TVYINETYT K IN - LKRE DIA L QKKCIQEA EEL MEKERAEY 230
Cdd:TIGR02169 344 E I EEER K RRDK L T E EYA EL KEELEDLRAE L EEVDKEF A E T RDELKDYRE K LE k LKRE INE L KRELDRLQ EEL QRLSEELA 423
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 231 LIRKQ -- ELT A Q INE F E NTR E V K RM E TYQKKKE L DK L QTKM SK IKE tvtvsaavlsdhnl E IAR L H E SIRYW E Q E V S E L K 308
Cdd:TIGR02169 424 DLNAA ia GIE A K INE L E EEK E D K AL E IKKQEWK L EQ L AADL SK YEQ -------------- E LYD L K E EYDRV E K E L S K L Q 489
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 309 KD LA IL EA KLCFFTDNKEKLDDIS n DEKNEFLNKIKQL V ET L HAARME Y KDLR E KMKT l A R QYKI V LSEEEK A FLQKQKI 388
Cdd:TIGR02169 490 RE LA EA EA QARASEERVRGGRAVE - EVLKASIQGVHGT V AQ L GSVGER Y ATAI E VAAG - N R LNNV V VEDDAV A KEAIELL 567
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 389 HDENQKQL TF ISQKEYFLSQKRVD I KNMEEGLITL ------- QELQQ A T K T V YQQQIKILSA nler E SQ R CVITQWK M AC 461
Cdd:TIGR02169 568 KRRKAGRA TF LPLNKMRDERRDLS I LSEDGVIGFA vdlvefd PKYEP A F K Y V FGDTLVVEDI ---- E AA R RLMGKYR M VT 643
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 462 L ----------------- RKKHARWTAKIK AE I Q AIT E KIQ naevrri E L LN E T S FR Q Q E ISGFVAQIEK L TT EL KEEEK 524
Cdd:TIGR02169 644 L egelfeksgamtggsra PRGGILFSRSEP AE L Q RLR E RLE ------- G L KR E L S SL Q S E LRRIENRLDE L SQ EL SDASR 716
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767981427 525 AFVNK EK --- M L MK E LS K Y - E EIFVK E TQI n KEK E E E LVEYLPQ L QVA E QEYK E KRRK L EE L SNIIT D D E R R D 593
Cdd:TIGR02169 717 KIGEI EK eie Q L EQ E EE K L k E RLEEL E EDL - SSL E Q E IENVKSE L KEL E ARIE E LEED L HK L EEALN D L E A R L 788
CCDC158
pfam15921 Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
292-597
3.67e-03
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain]
Cd Length: 1112
Bit Score: 40.49
E-value: 3.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 292 RL H ES IRYW E QEVSE L KKDLAI L EA KL CFFTDNKEKLD DI --- SNDEKNEFL N KIKQL V ET L H AA RMEYK D LR E KMK T LA 368
Cdd:pfam15921 93 RL N ES NELH E KQKFY L RQSVID L QT KL QEMQMERDAMA DI rrr ESQSQEDLR N QLQNT V HE L E AA KCLKE D ML E DSN T QI 172
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 369 R Q Y - K IV LS E E ------------- E K A FLQ K QKI HD e NQKQLT F I S QK --- EYF L SQKRVD I KNMEEGLITLQELQQ A T K 431
Cdd:pfam15921 173 E Q L r K MM LS H E gvlqeirsilvdf E E A SGK K IYE HD - SMSTMH F R S LG sai SKI L RELDTE I SYLKGRIFPVEDQLE A L K 251
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 432 TVY Q QQ I KI L san L ERESQ R cv I T Q wkmac L RKK H arwtaki KA EI QAI TEK IQN A ----------- E VRRIELL N ET S F 500
Cdd:pfam15921 252 SES Q NK I EL L --- L QQHQD R -- I E Q ----- L ISE H ------- EV EI TGL TEK ASS A rsqansiqsql E IIQEQAR N QN S M 314
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 501 RQQEI S GFVAQIEK L TT EL K E EEKAFVN K EKM L M K E L ---- S KYE E IFVKET Q INK E K --- EEE L VEY L PQ L QVA E Q E Y - 572
Cdd:pfam15921 315 YMRQL S DLESTVSQ L RS EL R E AKRMYED K IEE L E K Q L vlan S ELT E ARTERD Q FSQ E S gnl DDQ L QKL L AD L HKR E K E L s 394
330 340 350
....*....|....*....|....*....|
gi 767981427 573 -- KE KRRK L -- EELS N I IT D D E - RR DMGI R 597
Cdd:pfam15921 395 le KE QNKR L wd RDTG N S IT I D H l RR ELDD R 424
PRK02224
PRK02224 DNA double-strand break repair Rad50 ATPase;
205-593
4.17e-03
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain]
Cd Length: 880
Bit Score: 40.41
E-value: 4.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 205 K RE DIALQKKC I QEAE E LM --- E K ER A E YLIRKQE L TAQIN E F E NT R EVKRM E TYQKKKE ------- LDK L QTKMSKIKE 274
Cdd:PRK02224 249 R RE ELETLEAE I EDLR E TI aet E R ER E E LAEEVRD L RERLE E L E EE R DDLLA E AGLDDAD aeavear REE L EDRDEELRD 328
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 275 TVTVSAAVLSD HN L E IAR L H E SIRYW E QEVS EL KKDL A I LE AK L cff TDNK E KLD D isndekne FLNK I KQ L V E TLHAA R 354
Cdd:PRK02224 329 RLEECRVAAQA HN E E AES L R E DADDL E ERAE EL REEA A E LE SE L --- EEAR E AVE D -------- RREE I EE L E E EIEEL R 397
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 355 MEYK D LREKMKTLARQYKIVLS E eekaflqkqki H DE NQKQLT fisqkeyfls QKRVDIKNME E GLITLQE L QQ A T K --- 431
Cdd:PRK02224 398 ERFG D APVDLGNAEDFLEELRE E ----------- R DE LREREA ---------- ELEATLRTAR E RVEEAEA L LE A G K cpe 456
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 432 -------------- TVYQQQIKI L S A N LE R - E SQR cvitqwkm ACLRKKHA R WTAKIK AE -- I QAIT E KIQNA E VRRI E L 494
Cdd:PRK02224 457 cgqpvegsphveti EEDRERVEE L E A E LE D l E EEV -------- EEVEERLE R AEDLVE AE dr I ERLE E RREDL E ELIA E R 528
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 495 LNETSFRQQEISGFVAQIEK L TT E LK E EEK A FVNK E KMLMKELSKYE E IFV K ETQINKEK E -- E ELVEY L PQLQV AE Q E Y 572
Cdd:PRK02224 529 RETIEEKRERAEELRERAAE L EA E AE E KRE A AAEA E EEAEEAREEVA E LNS K LAELKERI E sl E RIRTL L AAIAD AE D E I 608
410 420
....*....|....*....|.
gi 767981427 573 KEK R R K L E E L SNI it D DERR D 593
Cdd:PRK02224 609 ERL R E K R E A L AEL -- N DERR E 627
COG5022
COG5022 Myosin heavy chain [General function prediction only];
109-367
6.32e-03
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain]
Cd Length: 1463
Bit Score: 39.68
E-value: 6.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 109 L PNS IKRE LEECVRDARRLN L f EINTIKMRIT R TEN eiel L KK KITD L T K YNEA L GEK Q E - ELA RK harfvlsln Q TM E K 187
Cdd:COG5022 822 L QKT IKRE KKLRETEEVEFS L - KAEVLIQKFG R SLK ---- A KK RFSL L K K ETIY L QSA Q R v ELA ER --------- Q LQ E L 887
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 188 K ATTT v Y I NETYTK i NL KR E DIALQK K CIQEAEELMEK E RAEY LI RKQELTAQINEF E NTREVK rmet Y Q K KK EL D KL QT 267
Cdd:COG5022 888 K IDVK - S I SSLKLV - NL EL E SEIIEL K KSLSSDLIENL E FKTE LI ARLKKLLNNIDL E EGPSIE ---- Y V K LP EL N KL HE 961
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 268 KM SK I KET VTVSAAV L SDHNLEIARLH --- ESIRYWEQ E VS EL K K DLAI L EAKLCFFTDNKEKLDDISNDE K ----- NEF 339
Cdd:COG5022 962 VE SK L KET SEEYEDL L KKSTILVREGN kan SELKNFKK E LA EL S K QYGA L QESTKQLKELPVEVAELQSAS K iisse STE 1041
250 260
....*....|....*....|....*...
gi 767981427 340 L NKI K Q L VETLHAARM E YKD L REKM K T L 367
Cdd:COG5022 1042 L SIL K P L QKLKGLLLL E NNQ L QARY K A L 1069
EnvC
COG4942 Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
257-483
8.93e-03
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain]
Cd Length: 377
Bit Score: 38.98
E-value: 8.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 257 QKKK EL DK LQ TKMSKIKETVTVSAAVLSDHNLEI A R L HES I RYWEQEVSE L KKD LA I LEA K L cfftdnkeklddisndek 336
Cdd:COG4942 24 EAEA EL EQ LQ QEIAELEKELAALKKEEKALLKQL A A L ERR I AALARRIRA L EQE LA A LEA E L ------------------ 85
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 337 N E FLNK I KQ L VET L H A ARM E YKD L REKMKT L A RQ -- YKIV LS E E EKAFLQK ----- QKIHDENQK Q LTFISQKEYF L SQK 409
Cdd:COG4942 86 A E LEKE I AE L RAE L E A QKE E LAE L LRALYR L G RQ pp LALL LS P E DFLDAVR rlqyl KYLAPARRE Q AEELRADLAE L AAL 165
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767981427 410 R VDIKNMEEG L IT L QELQQATKTVYQQQIKILSAN L E R ESQRCVITQWKM A C L RKKHARWT A K I KAEIQAITEK 483
Cdd:COG4942 166 R AELEAERAE L EA L LAELEEERAALEALKAERQKL L A R LEKELAELAAEL A E L QQEAEELE A L I ARLEAEAAAA 239
COG4913
COG4913 Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
335-585
9.82e-03
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain]
Cd Length: 1089
Bit Score: 39.13
E-value: 9.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 335 E KNEFLNKIKQ LVE --- T L HA A RMEYK D L RE KMKT L AR qykiv LS E EEKAFLQKQKIHD E NQKQLT ---- FIS Q KEYF L S 407
Cdd:COG4913 219 E EPDTFEAADA LVE hfd D L ER A HEALE D A RE QIEL L EP ----- IR E LAERYAAARERLA E LEYLRA alrl WFA Q RRLE L L 293
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 408 QKRVDIKN meeglitl Q EL QQA tktvy QQQIKI L S A N L ERESQR cvitqwkmac L RKKH A RWTAKIKAEIQAITEK I QNA 487
Cdd:COG4913 294 EAELEELR -------- A EL ARL ----- EAELER L E A R L DALREE ---------- L DELE A QIRGNGGDRLEQLERE I ERL 350
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981427 488 E VRRI E llnetsf R QQEISGFV A QIEK L TTE L KEEEKA F VNKEKMLMKE L SKY EE IF vketqin KEK EE E L V E YLPQ L QV 567
Cdd:COG4913 351 E RELE E ------- R ERRRARLE A LLAA L GLP L PASAEE F AALRAEAAAL L EAL EE EL ------- EAL EE A L A E AEAA L RD 416
250 260
....*....|....*....|..
gi 767981427 568 AEQ E YK E KRRKLEE L ---- SNI 585
Cdd:COG4913 417 LRR E LR E LEAEIAS L errk SNI 438
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
