NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|767993478|ref|XP_011522592|]
View 

putative sodium-coupled neutral amino acid transporter 10 isoform X4 [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
SLC5-6-like_sbd super family cl00456
Solute carrier families 5 and 6-like; solute binding domain; This superfamily includes the ...
 2-299 3.96e-36

Solute carrier families 5 and 6-like; solute binding domain; This superfamily includes the solute-binding domain of SLC5 proteins (also called the sodium/glucose cotransporters or solute sodium symporters), SLC6 proteins (also called the sodium- and chloride-dependent neurotransmitter transporters or Na+/Cl--dependent transporters), and nucleobase-cation-symport-1 (NCS1) transporters. SLC5s co-transport Na+ with sugars, amino acids, inorganic ions or vitamins. SLC6s include Na+/Cl--dependent plasma membrane transporters for the monoamine neurotransmitters serotonin, dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. Members of this superfamily are important in human physiology and disease. They contain a functional core of 10 transmembrane helices (TMs): an inverted structural repeat, TMs1-5 and TMs6-10; TMs numbered to conform to the SLC6 Aquifex aeolicus LeuT.


The actual alignment was detected with superfamily member pfam01490:

Pssm-ID: 444915  Cd Length: 410  Bit Score: 142.06  E-value: 3.96e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478     2 LVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGfqvGGTFRMFLLFAVSLCIVLPLSLQRNMMA-SIQS-FSAMALLFY 79
Cdd:pfam01490   86 LILFAILLNLFGVCISYLIFAGDNLPAIFDSFFD---TCPISLVYFIIIFGLIFIPLSFIPNLSAlSILSlLAAVSSLYY 162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478    80 TVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSV-KTMSSIFASSLNVVTTF 158
Cdd:pfam01490  163 IVILVLSVAEGIVLTAQGVGHLGSKTNIKLAGTFLAIGIIVFAFEGHAVLLPIQNEMKNPSKfKAMTKILLTAIIIATVL 242

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478   159 YVMVGFFGYVSFTEATAGNVLMHFP-SNLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLLceqQQKDGTFAAGGYMPP- 236
Cdd:pfam01490  243 YILIGLVGYLAFGDNVKGNILLNLPkSAWLIDIANLLLVLHVILSFPLQLFPIRQIVENLL---FRKEAPFGASGKNNPk 319

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767993478   237 --LRFKALTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKIHKNALSSQVVLW 299
Cdd:pfam01490  320 skLLRVVIRSGLVVITYLIAISVPFFGDLLSLVGATSCAPLSFILPPLFHLKLKKTKKKSQEKLW 384
PRK07764 super family cl35613
DNA polymerase III subunits gamma and tau; Validated
 449-886 5.37e-08

DNA polymerase III subunits gamma and tau; Validated


The actual alignment was detected with superfamily member PRK07764:

Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 56.92  E-value: 5.37e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  449 APGVQGQMAPPLPDSER-EKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQA 527
Cdd:PRK07764  364 LPSASDDERGLLARLERlERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPS 443

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  528 VLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAedsdhggkpPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLE- 606
Cdd:PRK07764  444 PAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPT---------AAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRe 514

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  607 --AEIKKIVAEAGR---AEMLDHAVLLQVIKEQQV-------QQKRLLDQQ--EKLLAVIeeqHKEIHQQRQEDeedkpr 672
Cdd:PRK07764  515 rwPEILAAVPKRSRktwAILLPEATVLGVRGDTLVlgfstggLARRFASPGnaEVLVTAL---AEELGGDWQVE------ 585

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  673 qVEVHQEPGAAVPRGQEAPEGKARETVENLPPLPLDPVLRAPGGRPAPSQ--DLNQRSLEHSEGPVGRDPAGPPDGGPDT 750
Cdd:PRK07764  586 -AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAapAEASAAPAPGVAAPEHHPKHVAVPDASD 664

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  751 EPRAAQAKLRDGQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQDVTGGSQDRKkpgkevAATGT 830
Cdd:PRK07764  665 GGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSP------AADDP 738

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767993478  831 SILKEANWLVAGPGAETGDPrmkpkqvsrdlglAADLPGGAEGAAAQPQAVLRQPE 886
Cdd:PRK07764  739 VPLPPEPDDPPDPAGAPAQP-------------PPPPAPAPAAAPAAAPPPSPPSE 781
 
Name Accession Description Interval E-value
Aa_trans pfam01490
Transmembrane amino acid transporter protein; This transmembrane region is found in many amino ...
 2-299 3.96e-36

Transmembrane amino acid transporter protein; This transmembrane region is found in many amino acid transporters including UNC-47 and MTR. UNC-47 encodes a vesicular amino butyric acid (GABA) transporter, (VGAT). UNC-47 is predicted to have 10 transmembrane domains. MTR is a N system amino acid transporter system protein involved in methyltryptophan resistance. Other members of this family include proline transporters and amino acid permeases.


Pssm-ID: 279788  Cd Length: 410  Bit Score: 142.06  E-value: 3.96e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478     2 LVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGfqvGGTFRMFLLFAVSLCIVLPLSLQRNMMA-SIQS-FSAMALLFY 79
Cdd:pfam01490   86 LILFAILLNLFGVCISYLIFAGDNLPAIFDSFFD---TCPISLVYFIIIFGLIFIPLSFIPNLSAlSILSlLAAVSSLYY 162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478    80 TVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSV-KTMSSIFASSLNVVTTF 158
Cdd:pfam01490  163 IVILVLSVAEGIVLTAQGVGHLGSKTNIKLAGTFLAIGIIVFAFEGHAVLLPIQNEMKNPSKfKAMTKILLTAIIIATVL 242

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478   159 YVMVGFFGYVSFTEATAGNVLMHFP-SNLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLLceqQQKDGTFAAGGYMPP- 236
Cdd:pfam01490  243 YILIGLVGYLAFGDNVKGNILLNLPkSAWLIDIANLLLVLHVILSFPLQLFPIRQIVENLL---FRKEAPFGASGKNNPk 319

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767993478   237 --LRFKALTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKIHKNALSSQVVLW 299
Cdd:pfam01490  320 skLLRVVIRSGLVVITYLIAISVPFFGDLLSLVGATSCAPLSFILPPLFHLKLKKTKKKSQEKLW 384
PTZ00206 PTZ00206
amino acid transporter; Provisional
 15-284 1.16e-17

amino acid transporter; Provisional


Pssm-ID: 240313  Cd Length: 467  Bit Score: 87.23  E-value: 1.16e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478   15 CIAFYVVIGDL------GSNffARLFGFQVGGTfrMFLLFAVSLCIVLPLSLQRNMmASIQSFSAMALLFYTVFMFVIVL 88
Cdd:PTZ00206  151 CVAYVISVGDIlsatlkGTN--APDFLKQKSGN--RLLTSLMWLCFMLPLVIPRHI-DSLRYVSTIAVSFMVYLVIVIVV 225

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478   89 SSLKHGLfsGQWLRRVSY--------VRWEGVFRCIP---IFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVVTT 157
Cdd:PTZ00206  226 HSCMNGL--PENIKNVSVgkddnaeiILFNSGNRAIEglgVFIFAYVFQITAYEVYMDMTNRSVGKFVLASTIAMGMCFT 303

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  158 FYVMVGFFGYVSFTEATAGNVLMHF-PSNLVTEMLR-VGFMMSVAVGFPMMILPCRQALSTLLCEQQQKDGTFAAGgymp 235
Cdd:PTZ00206  304 MYVLTAFFGYMDFGRNVTGSVLLMYdPVNEPAIMVGfVGVLVKLFVSYALLGMACRNALYDVIGWDARKVAFWKHC---- 379

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 767993478  236 plrFKALTLSVVFgtMVGGILIPNVETILGLTGATMGSLICFICPALIY 284
Cdd:PTZ00206  380 ---IAVVTLSVVM--LLCGLFIPKINTVLGFAGSISGGLLGFILPALLF 423
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 449-886 5.37e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 56.92  E-value: 5.37e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  449 APGVQGQMAPPLPDSER-EKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQA 527
Cdd:PRK07764  364 LPSASDDERGLLARLERlERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPS 443

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  528 VLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAedsdhggkpPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLE- 606
Cdd:PRK07764  444 PAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPT---------AAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRe 514

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  607 --AEIKKIVAEAGR---AEMLDHAVLLQVIKEQQV-------QQKRLLDQQ--EKLLAVIeeqHKEIHQQRQEDeedkpr 672
Cdd:PRK07764  515 rwPEILAAVPKRSRktwAILLPEATVLGVRGDTLVlgfstggLARRFASPGnaEVLVTAL---AEELGGDWQVE------ 585

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  673 qVEVHQEPGAAVPRGQEAPEGKARETVENLPPLPLDPVLRAPGGRPAPSQ--DLNQRSLEHSEGPVGRDPAGPPDGGPDT 750
Cdd:PRK07764  586 -AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAapAEASAAPAPGVAAPEHHPKHVAVPDASD 664

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  751 EPRAAQAKLRDGQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQDVTGGSQDRKkpgkevAATGT 830
Cdd:PRK07764  665 GGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSP------AADDP 738

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767993478  831 SILKEANWLVAGPGAETGDPrmkpkqvsrdlglAADLPGGAEGAAAQPQAVLRQPE 886
Cdd:PRK07764  739 VPLPPEPDDPPDPAGAPAQP-------------PPPPAPAPAAAPAAAPPPSPPSE 781
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
588-676 4.28e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 40.63  E-value: 4.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  588 REQRDVERAggnQAASQLEAEIKKIVAEAgraemldhAVLLQ-VIKEQQVQQKRLLDQQEKllaVIEEQHKEIHQQRQED 666
Cdd:COG2268   241 EAEAELAKK---KAEERREAETARAEAEA--------AYEIAeANAEREVQRQLEIAERER---EIELQEKEAEREEAEL 306

                          90
                  ....*....|
gi 767993478  667 EEDKPRQVEV 676
Cdd:COG2268   307 EADVRKPAEA 316
 
Name Accession Description Interval E-value
Aa_trans pfam01490
Transmembrane amino acid transporter protein; This transmembrane region is found in many amino ...
 2-299 3.96e-36

Transmembrane amino acid transporter protein; This transmembrane region is found in many amino acid transporters including UNC-47 and MTR. UNC-47 encodes a vesicular amino butyric acid (GABA) transporter, (VGAT). UNC-47 is predicted to have 10 transmembrane domains. MTR is a N system amino acid transporter system protein involved in methyltryptophan resistance. Other members of this family include proline transporters and amino acid permeases.


Pssm-ID: 279788  Cd Length: 410  Bit Score: 142.06  E-value: 3.96e-36
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478     2 LVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGfqvGGTFRMFLLFAVSLCIVLPLSLQRNMMA-SIQS-FSAMALLFY 79
Cdd:pfam01490   86 LILFAILLNLFGVCISYLIFAGDNLPAIFDSFFD---TCPISLVYFIIIFGLIFIPLSFIPNLSAlSILSlLAAVSSLYY 162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478    80 TVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSV-KTMSSIFASSLNVVTTF 158
Cdd:pfam01490  163 IVILVLSVAEGIVLTAQGVGHLGSKTNIKLAGTFLAIGIIVFAFEGHAVLLPIQNEMKNPSKfKAMTKILLTAIIIATVL 242

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478   159 YVMVGFFGYVSFTEATAGNVLMHFP-SNLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLLceqQQKDGTFAAGGYMPP- 236
Cdd:pfam01490  243 YILIGLVGYLAFGDNVKGNILLNLPkSAWLIDIANLLLVLHVILSFPLQLFPIRQIVENLL---FRKEAPFGASGKNNPk 319

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767993478   237 --LRFKALTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKIHKNALSSQVVLW 299
Cdd:pfam01490  320 skLLRVVIRSGLVVITYLIAISVPFFGDLLSLVGATSCAPLSFILPPLFHLKLKKTKKKSQEKLW 384
PTZ00206 PTZ00206
amino acid transporter; Provisional
 15-284 1.16e-17

amino acid transporter; Provisional


Pssm-ID: 240313  Cd Length: 467  Bit Score: 87.23  E-value: 1.16e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478   15 CIAFYVVIGDL------GSNffARLFGFQVGGTfrMFLLFAVSLCIVLPLSLQRNMmASIQSFSAMALLFYTVFMFVIVL 88
Cdd:PTZ00206  151 CVAYVISVGDIlsatlkGTN--APDFLKQKSGN--RLLTSLMWLCFMLPLVIPRHI-DSLRYVSTIAVSFMVYLVIVIVV 225

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478   89 SSLKHGLfsGQWLRRVSY--------VRWEGVFRCIP---IFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVVTT 157
Cdd:PTZ00206  226 HSCMNGL--PENIKNVSVgkddnaeiILFNSGNRAIEglgVFIFAYVFQITAYEVYMDMTNRSVGKFVLASTIAMGMCFT 303

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  158 FYVMVGFFGYVSFTEATAGNVLMHF-PSNLVTEMLR-VGFMMSVAVGFPMMILPCRQALSTLLCEQQQKDGTFAAGgymp 235
Cdd:PTZ00206  304 MYVLTAFFGYMDFGRNVTGSVLLMYdPVNEPAIMVGfVGVLVKLFVSYALLGMACRNALYDVIGWDARKVAFWKHC---- 379

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 767993478  236 plrFKALTLSVVFgtMVGGILIPNVETILGLTGATMGSLICFICPALIY 284
Cdd:PTZ00206  380 ---IAVVTLSVVM--LLCGLFIPKINTVLGFAGSISGGLLGFILPALLF 423
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 449-886 5.37e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 56.92  E-value: 5.37e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  449 APGVQGQMAPPLPDSER-EKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQA 527
Cdd:PRK07764  364 LPSASDDERGLLARLERlERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPS 443

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  528 VLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAedsdhggkpPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLE- 606
Cdd:PRK07764  444 PAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPT---------AAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRe 514

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  607 --AEIKKIVAEAGR---AEMLDHAVLLQVIKEQQV-------QQKRLLDQQ--EKLLAVIeeqHKEIHQQRQEDeedkpr 672
Cdd:PRK07764  515 rwPEILAAVPKRSRktwAILLPEATVLGVRGDTLVlgfstggLARRFASPGnaEVLVTAL---AEELGGDWQVE------ 585

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  673 qVEVHQEPGAAVPRGQEAPEGKARETVENLPPLPLDPVLRAPGGRPAPSQ--DLNQRSLEHSEGPVGRDPAGPPDGGPDT 750
Cdd:PRK07764  586 -AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAapAEASAAPAPGVAAPEHHPKHVAVPDASD 664

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  751 EPRAAQAKLRDGQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQDVTGGSQDRKkpgkevAATGT 830
Cdd:PRK07764  665 GGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSP------AADDP 738

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767993478  831 SILKEANWLVAGPGAETGDPrmkpkqvsrdlglAADLPGGAEGAAAQPQAVLRQPE 886
Cdd:PRK07764  739 VPLPPEPDDPPDPAGAPAQP-------------PPPPAPAPAAAPAAAPPPSPPSE 781
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 351-692 1.79e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 45.84  E-value: 1.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  351 PVVAVAEDGREKPKLPKEREELEQAqiKGPVDvPGREDGKEAPEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKVVVDEGQ 430
Cdd:PTZ00449  573 PTLSKKPEFPKDPKHPKDPEEPKKP--KRPRS-AQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPE 649

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  431 DREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVP----------- 499
Cdd:PTZ00449  650 GPKIIKSPKPPKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPrplppklprde 729

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  500 EADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPPPgNAAGDTGQPAEDSDhggKPPLPAEKPAP 579
Cdd:PTZ00449  730 EFPFEPIGDPDAEQPDDIEFFTPPEEERTFFHETPADTPLPDILAEEFKEE-DIHAETGEPDEAMK---RPDSPSEHEDK 805

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  580 GPGLPPE-PREQRDVERAGgnQAASQLEAEIKKIVAEAG-------RAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAV 651
Cdd:PTZ00449  806 PPGDHPSlPKKRHRLDGLA--LSTTDLESDAGRIAKDASgkivklkRSKSFDDLTTVEEAEEMGAEARKIVVDDDGTEAD 883

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 767993478  652 IEEQHKEIHQQRQEDEEDKPRQvEVHQEPGAAVPRGQEAPE 692
Cdd:PTZ00449  884 DEDTHPPEEKHKSEVRRRRPPK-KPSKPKKPSKPKKPKKPD 923
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 435-603 2.02e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 45.36  E-value: 2.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  435 PEENKPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPA-VQPAKED 513
Cdd:PRK07764  606 SGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAApAAPPPAP 685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  514 LGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDV 593
Cdd:PRK07764  686 APAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPA 765

                         170
                  ....*....|
gi 767993478  594 ERAGGNQAAS 603
Cdd:PRK07764  766 PAAAPAAAPP 775
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
682-892 2.46e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 45.23  E-value: 2.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  682 AAVPRGQEAPEGKARETVENLPPLPLDPVLRAPGGRPAPsQDLNQRSLEHSEGPVGRdPAGPPDGGPDTEPRAAQAKLrd 761
Cdd:PRK07003  374 ARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAP-KAAAAAAATRAEAPPAA-PAPPATADRGDDAADGDAPV-- 449

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  762 gQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQDvtggsqdrkkpgkEVAATGTSILKEANWLVA 841
Cdd:PRK07003  450 -PAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAA-------------APSAATPAAVPDARAPAA 515

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 767993478  842 GPGAETGDPRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPELRVISD 892
Cdd:PRK07003  516 ASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSD 566
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 350-800 5.41e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 44.31  E-value: 5.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  350 DPVVAVAEDGREKPKLPKEREELEQAQIKGPVDVPGREDGKEAPEEAQLDRPGQGIAVPVGE---AHRHEPPVPHDKVVV 426
Cdd:PRK10263  370 EPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQpyyAPAPEQPVAGNAWQA 449

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  427 DEGQDREVPEENKPPSRHAGGKAPGVQGQMAPPlPDSEREKQEPEQGEVGKRPGQAQA--LEEAGDLPEDPQKVPEADGQ 504
Cdd:PRK10263  450 EEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQ-PVEQQPVVEPEPVVEETKPARPPLyyFEEVEEKRAREREQLAAWYQ 528

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  505 PAVQPAKEDLgPGDRGLHPRPQAVLSEQQNGLAVGG-GEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPlPAEKPAPGPGL 583
Cdd:PRK10263  529 PIPEPVKEPE-PIKSSLKAPSVAAVPPVEAAAAVSPlASGVKKATLATGAAATVAAPVFSLANSGGPR-PQVKEGIGPQL 606

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  584 PPEPREQRDVER---AGGNQAASQLEAEIKKIVAEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIH 660
Cdd:PRK10263  607 PRPKRIRVPTRRelaSYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPV 686

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  661 QQRQED---EEDKPRQVEVHQE-------PGAAVPRGQEAPE-GKARETVENLPPLPLDPVLRAPGGRPApSQDLNQRSL 729
Cdd:PRK10263  687 NAEDADaaaEAELARQFAQTQQqrysgeqPAGANPFSLDDFEfSPMKALLDDGPHEPLFTPIVEPVQQPQ-QPVAPQQQY 765

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  730 EHSEGPVG--------RDPAGPP-DGGPDTEPRAAQAKLRDGQKDAAPRAAGTVKELPKGPE---QVPVPDPAREaggPE 797
Cdd:PRK10263  766 QQPQQPVApqpqyqqpQQPVAPQpQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQpqyQQPQQPVAPQ---PQ 842


                  ...
gi 767993478  798 ERL 800
Cdd:PRK10263  843 DTL 845
PHA03247 PHA03247
large tegument protein UL36; Provisional
 366-856 6.74e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.16  E-value: 6.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  366 PKEREELEQAQIKGPvDVPGREDGKEAPEEAQLDRPGQGIAVPVgeahrhePPVPHdkvvvdegqdrevPEENKPPSRHA 445
Cdd:PHA03247 2575 PRPSEPAVTSRARRP-DAPPQSARPRAPVDDRGDPRGPAPPSPL-------PPDTH-------------APDPPPPSPSP 2633

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  446 GGKAPGVQGQMAPPLPdsEREKQEPEQGEVgKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQP--AKEDLGPGDRGLHP 523
Cdd:PHA03247 2634 AANEPDPHPPPTVPPP--ERPRDDPAPGRV-SRPRRARRLGRAAQASSPPQRPRRRAARPTVGSltSLADPPPPPPTPEP 2710

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  524 RPQAVLSEQQNGLAVGGGEKAKGGPP----PGNAAGDTGQPAEDSdHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGN 599
Cdd:PHA03247 2711 APHALVSATPLPPGPAAARQASPALPaapaPPAVPAGPATPGGPA-RPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVA 2789

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  600 QAASQLEAEIKKIVAEAGRAEMLDHAVLLqvikeqqvqqkrlldqqekllavieeqhkeihqqrqedeedkprqvevhqe 679
Cdd:PHA03247 2790 SLSESRESLPSPWDPADPPAAVLAPAAAL--------------------------------------------------- 2818

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  680 PGAAVPRGQEAPEGKARETVENLPPLPLDPVLrAPGGRPAPSQDLNQRSlehsegpvgrdPAGPPDGGPDTEPRAAQAKL 759
Cdd:PHA03247 2819 PPAASPAGPLPPPTSAQPTAPPPPPGPPPPSL-PLGGSVAPGGDVRRRP-----------PSRSPAAKPAAPARPPVRRL 2886

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  760 rdgQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQDVTGGSQDRKKPGKEVAATG-TSILKEANW 838
Cdd:PHA03247 2887 ---ARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGePSGAVPQPW 2963

                         490
                  ....*....|....*...
gi 767993478  839 LVAGPGAETGDPRMKPKQ 856
Cdd:PHA03247 2964 LGALVPGRVAVPRFRVPQ 2981
PHA03169 PHA03169
hypothetical protein; Provisional
 366-588 1.59e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 42.27  E-value: 1.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  366 PKEREELEQAQIKGPVDVPGREDGKEAPEEaqldRPGQGIAVPVGE--AHRHEPPVPHDKVVVDEGQDREVPEENKP--P 441
Cdd:PHA03169   56 PQVRAVAEQGHRQTESDTETAEESRHGEKE----ERGQGGPSGSGSesVGSPTPSPSGSAEELASGLSPENTSGSSPesP 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  442 SRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQaqalEEAGDLPEDPQKVPEADGQPAVQ-PAKEDLGP-GDR 519
Cdd:PHA03169  132 ASHSPPPSPPSHPGPHEPAPPESHNPSPNQQPSSFLQPSH----EDSPEEPEPPTSEPEPDSPGPPQsETPTSSPPpQSP 207

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767993478  520 GLHPRPQavlseqqnglavgGGEKAKGGPPPgnaagDTGQPAEDSDHggkpplPAEKPAPGPGlPPEPR 588
Cdd:PHA03169  208 PDEPGEP-------------QSPTPQQAPSP-----NTQQAVEHEDE------PTEPEREGPP-FPGHR 251
PHA03321 PHA03321
tegument protein VP11/12; Provisional
 386-587 1.76e-03

tegument protein VP11/12; Provisional


Pssm-ID: 223041 [Multi-domain]  Cd Length: 694  Bit Score: 42.25  E-value: 1.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  386 REDgkEAPEEAQLDRPGQGIAVPVgEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPGVQGQM---APPLPD 462
Cdd:PHA03321  437 RRD--NDPPPPPRARPGSTPACAR-RARAQRARDAGPEYVDPLGALRRLPAGAAPPPEPAAAPSPATYYTRmggGPPRLP 513

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  463 SeREKQEPEQgevgkRPGQAQALEEAGDLPEDPQKVPEADGQPAvqpakEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGE 542
Cdd:PHA03321  514 P-RNRATETL-----RPDWGPPAAAPPEQMEDPYLEPDDDRFDR-----RDGAAAAATSHPREAPAPDDDPIYEGVSDSE 582

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767993478  543 ---------------------KAKGGPPPGNAAGDTGQPAEDSDHG------GKPPLPAEKPAPGPGLPPEP 587
Cdd:PHA03321  583 epvyeeiptprvyqnplprpmEGAGEPPDLDAPTSPWVEEENPIYGwgdsplFSPPPAARFPPPDPALSPEP 654
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 314-592 2.35e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.08  E-value: 2.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  314 SVSEEVPEDLAEEAPG---GRLGEAEGLMKVEAARLSAQDPVVAVAEDGREKPKLPKEREELEQAQIKGPVDVPGREDGK 390
Cdd:PHA03307   26 ATPGDAADDLLSGSQGqlvSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGS 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  391 EAPEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPGVQ-GQMAPPLPDSEREKQE 469
Cdd:PHA03307  106 PTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASsRQAALPLSSPEETARA 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  470 PEQGEVGKRPGQAQALEEAGDLPEDPqkvPEADGQPAVQPAkeDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPP 549
Cdd:PHA03307  186 PSSPPAEPPPSTPPAAASPRPPRRSS---PISASASSPAPA--PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRP 260

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 767993478  550 PGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRD 592
Cdd:PHA03307  261 APITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSP 303
PHA03169 PHA03169
hypothetical protein; Provisional
 420-594 3.14e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 41.11  E-value: 3.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  420 PHDKVVVDEGQDR-EVPEENKPPSRHAGGKAPGVQGqmapPLPDSEREKQEPEQGEVGKRPGQAQALE--------EAGD 490
Cdd:PHA03169   56 PQVRAVAEQGHRQtESDTETAEESRHGEKEERGQGG----PSGSGSESVGSPTPSPSGSAEELASGLSpentsgssPESP 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  491 LPEDPQKVPEADGQPAVQPAKEDLGP-----GDRGLHPRPQAVLSEqqnglavggGEKAKGGPPPGNAAGDTGQPAEDSD 565
Cdd:PHA03169  132 ASHSPPPSPPSHPGPHEPAPPESHNPspnqqPSSFLQPSHEDSPEE---------PEPPTSEPEPDSPGPPQSETPTSSP 202

                         170       180       190
                  ....*....|....*....|....*....|
gi 767993478  566 HGGKPP-LPAEKPAPGPGLPPEPREQRDVE 594
Cdd:PHA03169  203 PPQSPPdEPGEPQSPTPQQAPSPNTQQAVE 232
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
588-676 4.28e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 40.63  E-value: 4.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  588 REQRDVERAggnQAASQLEAEIKKIVAEAgraemldhAVLLQ-VIKEQQVQQKRLLDQQEKllaVIEEQHKEIHQQRQED 666
Cdd:COG2268   241 EAEAELAKK---KAEERREAETARAEAEA--------AYEIAeANAEREVQRQLEIAERER---EIELQEKEAEREEAEL 306

                          90
                  ....*....|
gi 767993478  667 EEDKPRQVEV 676
Cdd:COG2268   307 EADVRKPAEA 316
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
439-602 6.59e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.60  E-value: 6.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  439 KPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGD 518
Cdd:PRK07003  386 RAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDE 465

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  519 RGLHPRPQAVLSEQQNGLAVGGGEKAKgGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLP----PEPREQRDVE 594
Cdd:PRK07003  466 RDAQPPADSGSASAPASDAPPDAAFEP-APRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPearpPTPAAAAPAA 544


                  ....*...
gi 767993478  595 RAGGNQAA 602
Cdd:PRK07003  545 RAGGAAAA 552
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
 317-642 6.86e-03

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 40.43  E-value: 6.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  317 EEVPEDLAEEAPGGRLGEAEGLMKVEAARLSAQD---------PVVAVAEDGREKPKL-PKEREELEQAQIKGPVDVPGR 386
Cdd:COG5180   160 PILAKDPDGDSASTLPPPAEKLDKVLTEPRDALKdspekldrpKVEVKDEAQEEPPDLtGGADHPRPEAASSPKVDPPST 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  387 EDGKEAPeeaqLDRPGQGIAVPVGEAHRHEPPVPHDKvvvDEGQDREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSERE 466
Cdd:COG5180   240 SEARSRP----ATVDAQPEMRPPADAKERRRAAIGDT---PAAEPPGLPVLEAGSEPQSDAPEAETARPIDVKGVASAPP 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  467 KQEPEQGEVGKRPGQAQALEEAGdlpEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKG 546
Cdd:COG5180   313 ATRPVRPPGGARDPGTPRPGQPT---ERPAGVPEAASDAGQPPSAYPPAEEAVPGKPLEQGAPRPGSSGGDGAPFQPPNG 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  547 GPPPGN---AAGDTGQPAED-----SDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEAEIKKIVAEAGR 618
Cdd:COG5180   390 APQPGLgrrGAPGPPMGAGDlvqaaLDGGGRETASLGGAAGGAGQGPKADFVPGDAESVSGPAGLADQAGAAASTAMADF 469

                         330       340
                  ....*....|....*....|....
gi 767993478  619 AEMLDHAVLLQVIKEQQVQQKRLL 642
Cdd:COG5180   470 VAPVTDATPVDVADVLGVRPDAIL 493
dnaA PRK14086
chromosomal replication initiator protein DnaA;
457-600 7.60e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 40.19  E-value: 7.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  457 APPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPEDPqkvPEADGQPAVQPAKEDLGPGDR-GLHPRPQAVLSEQQNG 535
Cdd:PRK14086   95 PAPPPPHARRTSEPELPRPGRRPYEGYGGPRADDRPPGL---PRQDQLPTARPAYPAYQQRPEpGAWPRAADDYGWQQQR 171

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767993478  536 LavgggekakgGPPPGNaagDTGQPAEDSdhggkPPLPAEKPAPGPGLPPEPREQRDVERAGGNQ 600
Cdd:PRK14086  172 L----------GFPPRA---PYASPASYA-----PEQERDREPYDAGRPEYDQRRRDYDHPRPDW 218
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 405-594 8.52e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.97  E-value: 8.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  405 IAVPVGEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPG----VQGQMAPPLPDSEREKQEPEQGEVGKRP- 479
Cdd:PRK07764  588 VGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAapaeASAAPAPGVAAPEHHPKHVAVPDASDGGd 667

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  480 GQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEK---AKGGPPPGNAAGD 556
Cdd:PRK07764  668 GWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPspaADDPVPLPPEPDD 747

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 767993478  557 TGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDVE 594
Cdd:PRK07764  748 PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEM 785
PHA03247 PHA03247
large tegument protein UL36; Provisional
 351-581 8.60e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.31  E-value: 8.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  351 PVVAVAEDGREKPKLPKEREELEQaqikgPVDVPGREDGKEAPEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKV---VVD 427
Cdd:PHA03247 2784 TRPAVASLSESRESLPSPWDPADP-----PAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLggsVAP 2858

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  428 EGQDREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEvgKRPGQAQAleeagdlPEDPQKVPEADGQPAV 507
Cdd:PHA03247 2859 GGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQP--ERPPQPQA-------PPPPQPQPQPPPPPQP 2929

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767993478  508 QPAKEDlgpgdrglHPRPQAVLSEQQNglAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGP 581
Cdd:PHA03247 2930 QPPPPP--------PPRPQPPLAPTTD--PAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASST 2993
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 667-804 9.04e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.97  E-value: 9.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767993478  667 EEDKPRQVEVHQEPGAAVPRGQEAPEGKAREtvenlpplpldpvlrAPGGRPAPSQDLNQRSLEHSEGPVGRDPAGPPDG 746
Cdd:PRK07764  679 AAPPPAPAPAAPAAPAGAAPAQPAPAPAATP---------------PAGQADDPAAQPPQAAQGASAPSPAADDPVPLPP 743

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767993478  747 GPDTEPRAAQAKLRDGQKDAAPRAAGTVKELP---KGPEQVPVPDPAREAGGPEERLAEEF 804
Cdd:PRK07764  744 EPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPpspPSEEEEMAEDDAPSMDDEDRRDAEEV 804
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH