|
Name |
Accession |
Description |
Interval |
E-value |
| Fibrinogen_C |
pfam00147 |
Fibrinogen beta and gamma chains, C-terminal globular domain; |
1525-1734 |
3.49e-116 |
|
Fibrinogen beta and gamma chains, C-terminal globular domain;
:
Pssm-ID: 395095 [Multi-domain] Cd Length: 221 Bit Score: 366.08 E-value: 3.49e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1525 FPKDCSQAMLNGDTTSGLYTIYLNGDKaEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGD-RREEFWLGL 1603
Cdd:pfam00147 1 FGRDCSDVYNKGAKTSGLYTIRPDGAT-KPFEVYCDMETDGGGWTVFQRRLDGSTNFKRNWKDYKAGFGNlSPGEFWLGN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1604 DNLNKITAQGQYELRVDLRDH-GETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGD-------SMAYHNGRSFSTFDKDTD 1675
Cdd:pfam00147 80 DKIHLLTKQGPYVLRIDLEDWnGETVFALYDSFKVTNENDKYRLHVENYIGDAGDaldtagrSMTYHNGMQFSTWDRDND 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767957307 1676 SAITNCALSYKGAFWYRNCHRVNLMGRY--GDNNHSQ-GVNWFHWKGHEHSIQFAEMKLRPS 1734
Cdd:pfam00147 160 SPDGNCALSYGGGWWYNNCHAANLNGVYyyGGTYSKQnGIIWATWKGRWYSMKKAEMKIRPL 221
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
847-1241 |
5.60e-24 |
|
Fibronectin type 3 domain [General function prediction only];
:
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 108.94 E-value: 5.60e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 847 TTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKE----TFTTGLDAPRNLRRVSQTDNSITLEWR-NGKAAID 921
Cdd:COG3401 183 TSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEvsvtTPTTPPSAPTGLTATADTPGSVTLSWDpVTESDAT 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 922 SYRIKYAPISGGDHAEVdvpksqqATTKTTL---TGLRPGTEYGIGVSAVKEDKE----SNPATINAATEL-DTPKDLQV 993
Cdd:COG3401 263 GYRVYRSNSGDGPFTKV-------ATVTTTSytdTGLTNGTTYYYRVTAVDAAGNesapSNVVSVTTDLTPpAAPSGLTA 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 994 SETAETSLTLLW-KTPLAKFDRYRLNYS-LPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTA--EKGRHKSKPARVKA 1069
Cdd:COG3401 336 TAVGSSSITLSWtASSDADVTGYNVYRStSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAvdAAGNESAPSEEVSA 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1070 STEQAPELENLTVTEVGWDGLR-LNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVI 1148
Cdd:COG3401 416 TTASAASGESLTASVDAVPLTDvAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGS 495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1149 QGYRTPVLSAEASTGETPNLGEVVVAEV-GWDALKLNWTAPEGAYEYFfiQVQEADTV-EAAQNLTVPGGLRSTDLPGLK 1226
Cdd:COG3401 496 LVGGSGASSVTNSVSVIGASAAAAVGGApDGTPNVTGASPVTVGASTG--DVLITDLVsLTTSASSSVSGAGLGSGNLYL 573
|
410
....*....|....*
gi 767957307 1227 AATHYTITIRGVTQD 1241
Cdd:COG3401 574 ITTLGGSLLTTTSTN 588
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1137-1504 |
2.24e-17 |
|
Fibronectin type 3 domain [General function prediction only];
:
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 88.14 E-value: 2.24e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1137 ATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTApegayeyfFIQVQEADTVEAAQNLTVPGG 1216
Cdd:COG3401 28 KAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSG--------VAAVAVAAAPPTATGLTTLTG 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1217 LRSTDLPGLKAATHYTITirGVTQDFSTTPLSVEVLTAMG---SPKEVIFSDITENSATVSWRAPTAQVESFRITYVPIT 1293
Cdd:COG3401 100 SGSVGGATNTGLTSSDEV--PSPAVGTATTATAVAGGAATagtYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSAT 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1294 GGTPS-MVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSG----SFTTALDGPSGLVTANITDSEALARWQPAI 1368
Cdd:COG3401 178 AAVATtSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEvsvtTPTTPPSAPTGLTATADTPGSVTLSWDPVT 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1369 AT-VDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAE----KGPQKSSTITAkfTTDL---DSPRDLTA 1440
Cdd:COG3401 258 ESdATGYRVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVdaagNESAPSNVVSV--TTDLtppAAPSGLTA 335
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767957307 1441 TEVQSETALLTWRPPRAS-VTGYLlVY--ESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALN 1504
Cdd:COG3401 336 TAVGSSSITLSWTASSDAdVTGYN-VYrsTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVD 401
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
804-884 |
1.20e-12 |
|
Fibronectin type III domain;
:
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 65.13 E-value: 1.20e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 804 DAPSQIEVKDVTDTTALITWFKPL---AEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDM 880
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....
gi 767957307 881 SSNP 884
Cdd:pfam00041 81 EGPP 84
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
713-793 |
6.47e-12 |
|
Fibronectin type III domain;
:
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.82 E-value: 6.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 713 PAPEGLKFKSIKETSVEVEWDP---LDIAFETWEIIFRNMNKEDEgEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNN 789
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPppdGNGPITGYEVEYRPKNSGEP-WNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79
|
....
gi 767957307 790 TRGP 793
Cdd:pfam00041 80 GEGP 83
|
|
| FN3 super family |
cl27307 |
Fibronectin type 3 domain [General function prediction only]; |
624-779 |
4.85e-10 |
|
Fibronectin type 3 domain [General function prediction only];
The actual alignment was detected with superfamily member COG3401:
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 64.25 E-value: 4.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 624 SPPKDLVVTEVTEETVNLAWD--NEMRVTEYLVVYTPTHEGGLEmqfRVPGDQTSTII-QELEPGVEYFIRVFAI----L 696
Cdd:COG3401 234 SAPTGLTATADTPGSVTLSWDpvTESDATGYRVYRSNSGDGPFT---KVATVTTTSYTdTGLTNGTTYYYRVTAVdaagN 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 697 ENKKSIPVSARVATYLP-APEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDE-GEITKSLRrpETSYRQTGLA 774
Cdd:COG3401 311 ESAPSNVVSVTTDLTPPaAPSGLTATAVGSSSITLSWTASSDADVTGYNVYRSTSGGGTyTKIAETVT--TTSYTDTGLT 388
|
....*
gi 767957307 775 PGQEY 779
Cdd:COG3401 389 PGTTY 393
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
408-435 |
4.80e-06 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 44.60 E-value: 4.80e-06
10 20
....*....|....*....|....*...
gi 767957307 408 CPNGCSGHGRCVNGQCVCDEGYTGEDCS 435
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
501-528 |
2.11e-05 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 42.67 E-value: 2.11e-05
10 20
....*....|....*....|....*...
gi 767957307 501 CPRDCSNRGLCVDGQCVCEDGFTGPDCA 528
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
190-217 |
3.15e-05 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 42.29 E-value: 3.15e-05
10 20
....*....|....*....|....*...
gi 767957307 190 CPGNCHLRGRCIDGQCICDDGFTGEDCS 217
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
594-621 |
5.38e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 38.82 E-value: 5.38e-04
10 20
....*....|....*....|....*...
gi 767957307 594 CPSDCNNLGQCVSGRCICNEGYSGEDCS 621
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
439-466 |
1.38e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 37.66 E-value: 1.38e-03
10 20
....*....|....*....|....*...
gi 767957307 439 CPNDCHSRGRCVEGKCVCEQGFKGYDCS 466
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
377-403 |
1.42e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 37.66 E-value: 1.42e-03
10 20
....*....|....*....|....*..
gi 767957307 377 CPADCHNRGRCVDGRCECDDGFTGADC 403
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
470-496 |
2.21e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 37.28 E-value: 2.21e-03
10 20
....*....|....*....|....*..
gi 767957307 470 CPNDCHQHGRCVNGMCVCDDGYTGEDC 496
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
346-373 |
2.24e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 37.28 E-value: 2.24e-03
10 20
....*....|....*....|....*...
gi 767957307 346 CPHACHTQGRCEEGQCVCDEGFAGVDCS 373
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
563-589 |
3.88e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 36.51 E-value: 3.88e-03
10 20
....*....|....*....|....*..
gi 767957307 563 CPSDCHGQGRCVDGQCICHEGFTGLDC 589
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
535-558 |
8.34e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
:
Pssm-ID: 400365 Cd Length: 26 Bit Score: 35.40 E-value: 8.34e-03
10 20
....*....|....*....|....*.
gi 767957307 535 DCHGQGRCVN--GQCVCHEGFMGKDC 558
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Fibrinogen_C |
pfam00147 |
Fibrinogen beta and gamma chains, C-terminal globular domain; |
1525-1734 |
3.49e-116 |
|
Fibrinogen beta and gamma chains, C-terminal globular domain;
Pssm-ID: 395095 [Multi-domain] Cd Length: 221 Bit Score: 366.08 E-value: 3.49e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1525 FPKDCSQAMLNGDTTSGLYTIYLNGDKaEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGD-RREEFWLGL 1603
Cdd:pfam00147 1 FGRDCSDVYNKGAKTSGLYTIRPDGAT-KPFEVYCDMETDGGGWTVFQRRLDGSTNFKRNWKDYKAGFGNlSPGEFWLGN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1604 DNLNKITAQGQYELRVDLRDH-GETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGD-------SMAYHNGRSFSTFDKDTD 1675
Cdd:pfam00147 80 DKIHLLTKQGPYVLRIDLEDWnGETVFALYDSFKVTNENDKYRLHVENYIGDAGDaldtagrSMTYHNGMQFSTWDRDND 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767957307 1676 SAITNCALSYKGAFWYRNCHRVNLMGRY--GDNNHSQ-GVNWFHWKGHEHSIQFAEMKLRPS 1734
Cdd:pfam00147 160 SPDGNCALSYGGGWWYNNCHAANLNGVYyyGGTYSKQnGIIWATWKGRWYSMKKAEMKIRPL 221
|
|
| FReD |
cd00087 |
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ... |
1524-1733 |
4.96e-107 |
|
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.
Pssm-ID: 238040 [Multi-domain] Cd Length: 215 Bit Score: 339.99 E-value: 4.96e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1524 PFPKDCSQAMLNGDTTSGLYTIYLNGDKaEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGDRREEFWLGL 1603
Cdd:cd00087 1 PLPRDCSEVLQRGGRTSGVYTIQPPGSN-EPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1604 DNLNKITAQGQYELRVDLRD-HGETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCA 1682
Cdd:cd00087 80 EKIHLLTSQGPYELRIDLEDwEGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 767957307 1683 LSYKGAFWYRNCHRVNLMGRYG----DNNHSQGVNWFHWKGHEHSIQFAEMKLRP 1733
Cdd:cd00087 160 ESYSGGWWYNSCHASNLNGRYYsgghRNEYDNGINWATWKGSTYSLKFTEMKIRP 214
|
|
| FBG |
smart00186 |
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and ... |
1525-1733 |
4.10e-106 |
|
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and gamma chains, and a variety of fibrinogen-related proteins, including tenascin and Drosophila scabrous.
Pssm-ID: 214548 [Multi-domain] Cd Length: 212 Bit Score: 337.33 E-value: 4.10e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1525 FPKDCSQAMLNGDTTSGLYTIYLNGDKaEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGDRREEFWLGLD 1604
Cdd:smart00186 1 LPRDCSDVLQNGGKTSGLYTIYPDGSS-RPLKVYCDMETDGGGWTVIQRRMDGSVDFYRDWKDYKEGFGNLAGEFWLGNE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1605 NLNKITAQGQYELRVDLRD-HGETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGD-SMAYHNGRSFSTFDKDTDSAITNCA 1682
Cdd:smart00186 80 NIHLLTSQGKYELRIDLEDwEGNTAYALYDSFKVADEADGYRLHIGGYSGTAGDaSLTYHNGMQFSTYDRDNDKYSGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 767957307 1683 LSYKGAFWYRNCHRVNLMGRYG-DNNHSQGVNWFHWKGHEHSIQFAEMKLRP 1733
Cdd:smart00186 160 EEYGGGWWYNNCHAANLNGRYYpNNNYDNGINWATWKGSWYSLKFTEMKIRP 211
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
847-1241 |
5.60e-24 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 108.94 E-value: 5.60e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 847 TTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKE----TFTTGLDAPRNLRRVSQTDNSITLEWR-NGKAAID 921
Cdd:COG3401 183 TSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEvsvtTPTTPPSAPTGLTATADTPGSVTLSWDpVTESDAT 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 922 SYRIKYAPISGGDHAEVdvpksqqATTKTTL---TGLRPGTEYGIGVSAVKEDKE----SNPATINAATEL-DTPKDLQV 993
Cdd:COG3401 263 GYRVYRSNSGDGPFTKV-------ATVTTTSytdTGLTNGTTYYYRVTAVDAAGNesapSNVVSVTTDLTPpAAPSGLTA 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 994 SETAETSLTLLW-KTPLAKFDRYRLNYS-LPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTA--EKGRHKSKPARVKA 1069
Cdd:COG3401 336 TAVGSSSITLSWtASSDADVTGYNVYRStSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAvdAAGNESAPSEEVSA 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1070 STEQAPELENLTVTEVGWDGLR-LNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVI 1148
Cdd:COG3401 416 TTASAASGESLTASVDAVPLTDvAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGS 495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1149 QGYRTPVLSAEASTGETPNLGEVVVAEV-GWDALKLNWTAPEGAYEYFfiQVQEADTV-EAAQNLTVPGGLRSTDLPGLK 1226
Cdd:COG3401 496 LVGGSGASSVTNSVSVIGASAAAAVGGApDGTPNVTGASPVTVGASTG--DVLITDLVsLTTSASSSVSGAGLGSGNLYL 573
|
410
....*....|....*
gi 767957307 1227 AATHYTITIRGVTQD 1241
Cdd:COG3401 574 ITTLGGSLLTTTSTN 588
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1137-1504 |
2.24e-17 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 88.14 E-value: 2.24e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1137 ATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTApegayeyfFIQVQEADTVEAAQNLTVPGG 1216
Cdd:COG3401 28 KAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSG--------VAAVAVAAAPPTATGLTTLTG 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1217 LRSTDLPGLKAATHYTITirGVTQDFSTTPLSVEVLTAMG---SPKEVIFSDITENSATVSWRAPTAQVESFRITYVPIT 1293
Cdd:COG3401 100 SGSVGGATNTGLTSSDEV--PSPAVGTATTATAVAGGAATagtYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSAT 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1294 GGTPS-MVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSG----SFTTALDGPSGLVTANITDSEALARWQPAI 1368
Cdd:COG3401 178 AAVATtSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEvsvtTPTTPPSAPTGLTATADTPGSVTLSWDPVT 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1369 AT-VDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAE----KGPQKSSTITAkfTTDL---DSPRDLTA 1440
Cdd:COG3401 258 ESdATGYRVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVdaagNESAPSNVVSV--TTDLtppAAPSGLTA 335
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767957307 1441 TEVQSETALLTWRPPRAS-VTGYLlVY--ESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALN 1504
Cdd:COG3401 336 TAVGSSSITLSWTASSDAdVTGYN-VYrsTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVD 401
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1433-1505 |
2.60e-15 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 72.45 E-value: 2.60e-15
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767957307 1433 DSPRDLTATEVQSETALLTWRPPR---ASVTGYLLVYESVDGT--VKEVIVGPDTTSYSLADLSPSTHYTAKIQALNG 1505
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
894-976 |
2.28e-14 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 70.14 E-value: 2.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 894 DAPRNLRRVSQTDNSITLEW---RNGKAAIDSYRIKYAPISGGDHA-EVDVPKSqqaTTKTTLTGLRPGTEYGIGVSAVK 969
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWtppPDGNGPITGYEVEYRPKNSGEPWnEITVPGT---TTSVTLTGLKPGTEYEVRVQAVN 77
|
....*..
gi 767957307 970 EDKESNP 976
Cdd:pfam00041 78 GGGEGPP 84
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1433-1505 |
1.67e-13 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 67.64 E-value: 1.67e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767957307 1433 DSPRDLTATEVQSETALLTWRPPRAS-----VTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNG 1505
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNG 79
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
894-978 |
2.92e-13 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 67.14 E-value: 2.92e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 894 DAPRNLRRVSQTDNSITLEW---RNGKAAIDSYRIKYAPISGGDHAEVDVPKSQqaTTKTTLTGLRPGTEYGIGVSAVKE 970
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWtppEDDGGPITGYVVEYREKGSGDWKEVEVTPGS--ETSYTLTGLKPGTEYEFRVRAVNG 79
|
....*...
gi 767957307 971 DKESNPAT 978
Cdd:cd00063 80 GGESPPSE 87
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1256-1342 |
4.94e-13 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 66.37 E-value: 4.94e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1256 GSPKEVIFSDITENSATVSWRAPT---AQVESFRITYVPITGGTPSMVTV-DGTKTQTRLVKLIPGVEYLVSIIAMKGFE 1331
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVtPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 767957307 1332 ESEPV-SGSFTT 1342
Cdd:cd00063 82 ESPPSeSVTVTT 93
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
804-884 |
1.20e-12 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 65.13 E-value: 1.20e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 804 DAPSQIEVKDVTDTTALITWFKPL---AEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDM 880
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....
gi 767957307 881 SSNP 884
Cdd:pfam00041 81 EGPP 84
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
713-793 |
6.47e-12 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.82 E-value: 6.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 713 PAPEGLKFKSIKETSVEVEWDP---LDIAFETWEIIFRNMNKEDEgEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNN 789
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPppdGNGPITGYEVEYRPKNSGEP-WNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79
|
....
gi 767957307 790 TRGP 793
Cdd:pfam00041 80 GEGP 83
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
667-988 |
6.99e-12 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 70.42 E-value: 6.99e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 667 QFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIP---VSARVATYLP-APEGLKFKSIKETSVEVEWDPLDIAFETW 742
Cdd:COG3401 184 SLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPsneVSVTTPTTPPsAPTGLTATADTPGSVTLSWDPVTESDATG 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 743 EIIFRNMNKEDEGE-ITKSlrrPETSYRQTGLAPGQEYE--ISLHIVKNNTRGP-GLKRVTT--TRLDAPSQIEVKDVTD 816
Cdd:COG3401 264 YRVYRSNSGDGPFTkVATV---TTTSYTDTGLTNGTTYYyrVTAVDAAGNESAPsNVVSVTTdlTPPAAPSGLTATAVGS 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 817 TTALITWFKPLaeiDGIELTYGI---KDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGD-MSSNPAKETFTTG 892
Cdd:COG3401 341 SSITLSWTASS---DADVTGYNVyrsTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVDAAgNESAPSEEVSATT 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 893 LDAPR-----------NLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEY 961
Cdd:COG3401 418 ASAASgesltasvdavPLTDVAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGSLV 497
|
330 340
....*....|....*....|....*..
gi 767957307 962 GIGVSAVKEDKESNPATINAATELDTP 988
Cdd:COG3401 498 GGSGASSVTNSVSVIGASAAAAVGGAP 524
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
986-1062 |
1.65e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 61.86 E-value: 1.65e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 986 DTPKDLQVSETAETSLTLLWKTP-----LAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRH 1060
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPpddgiTGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 767957307 1061 KS 1062
Cdd:smart00060 82 EG 83
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
624-779 |
4.85e-10 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 64.25 E-value: 4.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 624 SPPKDLVVTEVTEETVNLAWD--NEMRVTEYLVVYTPTHEGGLEmqfRVPGDQTSTII-QELEPGVEYFIRVFAI----L 696
Cdd:COG3401 234 SAPTGLTATADTPGSVTLSWDpvTESDATGYRVYRSNSGDGPFT---KVATVTTTSYTdTGLTNGTTYYYRVTAVdaagN 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 697 ENKKSIPVSARVATYLP-APEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDE-GEITKSLRrpETSYRQTGLA 774
Cdd:COG3401 311 ESAPSNVVSVTTDLTPPaAPSGLTATAVGSSSITLSWTASSDADVTGYNVYRSTSGGGTyTKIAETVT--TTSYTDTGLT 388
|
....*
gi 767957307 775 PGQEY 779
Cdd:COG3401 389 PGTTY 393
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
804-882 |
1.93e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 56.08 E-value: 1.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 804 DAPSQIEVKDVTDTTALITWFKPLAE-IDGIELTYGIKDVPGDR--TTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDM 880
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPDDgITGYIVGYRVEYREEGSewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 767957307 881 SS 882
Cdd:smart00060 82 EG 83
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
624-695 |
1.70e-08 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 53.19 E-value: 1.70e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767957307 624 SPPKDLVVTEVTEETVNLAW----DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAI 695
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWtpppDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAV 76
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
624-710 |
1.88e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 53.27 E-value: 1.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 624 SPPKDLVVTEVTEETVNLAW----DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENK 699
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWtppeDDGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|.
gi 767957307 700 KSIPVSARVAT 710
Cdd:cd00063 82 ESPPSESVTVT 92
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
713-801 |
1.12e-07 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 51.34 E-value: 1.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 713 PAPEGLKFKSIKETSVEVEWDPLD---IAFETWEIIFRNMNKEDEGEITKSlRRPETSYRQTGLAPGQEYEISLHIVKNN 789
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVT-PGSETSYTLTGLKPGTEYEFRVRAVNGG 80
|
90
....*....|..
gi 767957307 790 TRGPGLKRVTTT 801
Cdd:cd00063 81 GESPPSESVTVT 92
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
713-794 |
2.34e-07 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 49.92 E-value: 2.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 713 PAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRP--ETSYRQTGLAPGQEYEISLHIVknNT 790
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPDDGITGYIVGYRVEYREEGSEWKEVNVTpsSTSYTLTGLKPGTEYEFRVRAV--NG 79
|
....
gi 767957307 791 RGPG 794
Cdd:smart00060 80 AGEG 83
|
|
| GGGWT_bact |
NF040941 |
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, ... |
1535-1568 |
4.79e-07 |
|
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, describes a conserved domain found in eukaryotic proteins such as fibrinogen beta and gamma chains, fincolin, and angiopoietin. This model describes a small homology domain, about 46 amino acids long, found in the PF00147 homology region of those proteins but also as a much shorter homology domain in bacterial proteins that may lack homology to those proteins, or to each other, outside this region. The signature motif, at the C-terminus of this domain, is YCDxTTDGGGWxLV.
Pssm-ID: 468872 [Multi-domain] Cd Length: 46 Bit Score: 47.94 E-value: 4.79e-07
10 20 30
....*....|....*....|....*....|....*
gi 767957307 1535 NGDTTSGLYTIYLNGD-KAEALEVFCDMTSDGGGW 1568
Cdd:NF040941 9 GPSAPSGVYWIDPDGMgGLAPFQVYCDMTTDGGGW 43
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
408-435 |
4.80e-06 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 44.60 E-value: 4.80e-06
10 20
....*....|....*....|....*...
gi 767957307 408 CPNGCSGHGRCVNGQCVCDEGYTGEDCS 435
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
501-528 |
2.11e-05 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 42.67 E-value: 2.11e-05
10 20
....*....|....*....|....*...
gi 767957307 501 CPRDCSNRGLCVDGQCVCEDGFTGPDCA 528
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
190-217 |
3.15e-05 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 42.29 E-value: 3.15e-05
10 20
....*....|....*....|....*...
gi 767957307 190 CPGNCHLRGRCIDGQCICDDGFTGEDCS 217
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
624-695 |
1.19e-04 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 42.22 E-value: 1.19e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767957307 624 SPPKDLVVTEVTEETVNLAWD------NEMRVTEYLVVYTPthEGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAI 695
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEpppddgITGYIVGYRVEYRE--EGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
594-621 |
5.38e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 38.82 E-value: 5.38e-04
10 20
....*....|....*....|....*...
gi 767957307 594 CPSDCNNLGQCVSGRCICNEGYSGEDCS 621
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
439-466 |
1.38e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.66 E-value: 1.38e-03
10 20
....*....|....*....|....*...
gi 767957307 439 CPNDCHSRGRCVEGKCVCEQGFKGYDCS 466
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
377-403 |
1.42e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.66 E-value: 1.42e-03
10 20
....*....|....*....|....*..
gi 767957307 377 CPADCHNRGRCVDGRCECDDGFTGADC 403
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
470-496 |
2.21e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.28 E-value: 2.21e-03
10 20
....*....|....*....|....*..
gi 767957307 470 CPNDCHQHGRCVNGMCVCDDGYTGEDC 496
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
346-373 |
2.24e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.28 E-value: 2.24e-03
10 20
....*....|....*....|....*...
gi 767957307 346 CPHACHTQGRCEEGQCVCDEGFAGVDCS 373
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
563-589 |
3.88e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 36.51 E-value: 3.88e-03
10 20
....*....|....*....|....*..
gi 767957307 563 CPSDCHGQGRCVDGQCICHEGFTGLDC 589
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
535-558 |
8.34e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 35.40 E-value: 8.34e-03
10 20
....*....|....*....|....*.
gi 767957307 535 DCHGQGRCVN--GQCVCHEGFMGKDC 558
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Fibrinogen_C |
pfam00147 |
Fibrinogen beta and gamma chains, C-terminal globular domain; |
1525-1734 |
3.49e-116 |
|
Fibrinogen beta and gamma chains, C-terminal globular domain;
Pssm-ID: 395095 [Multi-domain] Cd Length: 221 Bit Score: 366.08 E-value: 3.49e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1525 FPKDCSQAMLNGDTTSGLYTIYLNGDKaEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGD-RREEFWLGL 1603
Cdd:pfam00147 1 FGRDCSDVYNKGAKTSGLYTIRPDGAT-KPFEVYCDMETDGGGWTVFQRRLDGSTNFKRNWKDYKAGFGNlSPGEFWLGN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1604 DNLNKITAQGQYELRVDLRDH-GETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGD-------SMAYHNGRSFSTFDKDTD 1675
Cdd:pfam00147 80 DKIHLLTKQGPYVLRIDLEDWnGETVFALYDSFKVTNENDKYRLHVENYIGDAGDaldtagrSMTYHNGMQFSTWDRDND 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767957307 1676 SAITNCALSYKGAFWYRNCHRVNLMGRY--GDNNHSQ-GVNWFHWKGHEHSIQFAEMKLRPS 1734
Cdd:pfam00147 160 SPDGNCALSYGGGWWYNNCHAANLNGVYyyGGTYSKQnGIIWATWKGRWYSMKKAEMKIRPL 221
|
|
| FReD |
cd00087 |
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ... |
1524-1733 |
4.96e-107 |
|
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.
Pssm-ID: 238040 [Multi-domain] Cd Length: 215 Bit Score: 339.99 E-value: 4.96e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1524 PFPKDCSQAMLNGDTTSGLYTIYLNGDKaEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGDRREEFWLGL 1603
Cdd:cd00087 1 PLPRDCSEVLQRGGRTSGVYTIQPPGSN-EPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1604 DNLNKITAQGQYELRVDLRD-HGETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCA 1682
Cdd:cd00087 80 EKIHLLTSQGPYELRIDLEDwEGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 767957307 1683 LSYKGAFWYRNCHRVNLMGRYG----DNNHSQGVNWFHWKGHEHSIQFAEMKLRP 1733
Cdd:cd00087 160 ESYSGGWWYNSCHASNLNGRYYsgghRNEYDNGINWATWKGSTYSLKFTEMKIRP 214
|
|
| FBG |
smart00186 |
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and ... |
1525-1733 |
4.10e-106 |
|
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and gamma chains, and a variety of fibrinogen-related proteins, including tenascin and Drosophila scabrous.
Pssm-ID: 214548 [Multi-domain] Cd Length: 212 Bit Score: 337.33 E-value: 4.10e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1525 FPKDCSQAMLNGDTTSGLYTIYLNGDKaEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGDRREEFWLGLD 1604
Cdd:smart00186 1 LPRDCSDVLQNGGKTSGLYTIYPDGSS-RPLKVYCDMETDGGGWTVIQRRMDGSVDFYRDWKDYKEGFGNLAGEFWLGNE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1605 NLNKITAQGQYELRVDLRD-HGETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGD-SMAYHNGRSFSTFDKDTDSAITNCA 1682
Cdd:smart00186 80 NIHLLTSQGKYELRIDLEDwEGNTAYALYDSFKVADEADGYRLHIGGYSGTAGDaSLTYHNGMQFSTYDRDNDKYSGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 767957307 1683 LSYKGAFWYRNCHRVNLMGRYG-DNNHSQGVNWFHWKGHEHSIQFAEMKLRP 1733
Cdd:smart00186 160 EEYGGGWWYNNCHAANLNGRYYpNNNYDNGINWATWKGSWYSLKFTEMKIRP 211
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
847-1241 |
5.60e-24 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 108.94 E-value: 5.60e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 847 TTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKE----TFTTGLDAPRNLRRVSQTDNSITLEWR-NGKAAID 921
Cdd:COG3401 183 TSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEvsvtTPTTPPSAPTGLTATADTPGSVTLSWDpVTESDAT 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 922 SYRIKYAPISGGDHAEVdvpksqqATTKTTL---TGLRPGTEYGIGVSAVKEDKE----SNPATINAATEL-DTPKDLQV 993
Cdd:COG3401 263 GYRVYRSNSGDGPFTKV-------ATVTTTSytdTGLTNGTTYYYRVTAVDAAGNesapSNVVSVTTDLTPpAAPSGLTA 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 994 SETAETSLTLLW-KTPLAKFDRYRLNYS-LPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTA--EKGRHKSKPARVKA 1069
Cdd:COG3401 336 TAVGSSSITLSWtASSDADVTGYNVYRStSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAvdAAGNESAPSEEVSA 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1070 STEQAPELENLTVTEVGWDGLR-LNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVI 1148
Cdd:COG3401 416 TTASAASGESLTASVDAVPLTDvAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGS 495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1149 QGYRTPVLSAEASTGETPNLGEVVVAEV-GWDALKLNWTAPEGAYEYFfiQVQEADTV-EAAQNLTVPGGLRSTDLPGLK 1226
Cdd:COG3401 496 LVGGSGASSVTNSVSVIGASAAAAVGGApDGTPNVTGASPVTVGASTG--DVLITDLVsLTTSASSSVSGAGLGSGNLYL 573
|
410
....*....|....*
gi 767957307 1227 AATHYTITIRGVTQD 1241
Cdd:COG3401 574 ITTLGGSLLTTTSTN 588
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1137-1504 |
2.24e-17 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 88.14 E-value: 2.24e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1137 ATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTApegayeyfFIQVQEADTVEAAQNLTVPGG 1216
Cdd:COG3401 28 KAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSG--------VAAVAVAAAPPTATGLTTLTG 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1217 LRSTDLPGLKAATHYTITirGVTQDFSTTPLSVEVLTAMG---SPKEVIFSDITENSATVSWRAPTAQVESFRITYVPIT 1293
Cdd:COG3401 100 SGSVGGATNTGLTSSDEV--PSPAVGTATTATAVAGGAATagtYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSAT 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1294 GGTPS-MVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSG----SFTTALDGPSGLVTANITDSEALARWQPAI 1368
Cdd:COG3401 178 AAVATtSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEvsvtTPTTPPSAPTGLTATADTPGSVTLSWDPVT 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1369 AT-VDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAE----KGPQKSSTITAkfTTDL---DSPRDLTA 1440
Cdd:COG3401 258 ESdATGYRVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVdaagNESAPSNVVSV--TTDLtppAAPSGLTA 335
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767957307 1441 TEVQSETALLTWRPPRAS-VTGYLlVY--ESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALN 1504
Cdd:COG3401 336 TAVGSSSITLSWTASSDAdVTGYN-VYrsTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVD 401
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1433-1505 |
2.60e-15 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 72.45 E-value: 2.60e-15
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767957307 1433 DSPRDLTATEVQSETALLTWRPPR---ASVTGYLLVYESVDGT--VKEVIVGPDTTSYSLADLSPSTHYTAKIQALNG 1505
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
894-976 |
2.28e-14 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 70.14 E-value: 2.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 894 DAPRNLRRVSQTDNSITLEW---RNGKAAIDSYRIKYAPISGGDHA-EVDVPKSqqaTTKTTLTGLRPGTEYGIGVSAVK 969
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWtppPDGNGPITGYEVEYRPKNSGEPWnEITVPGT---TTSVTLTGLKPGTEYEVRVQAVN 77
|
....*..
gi 767957307 970 EDKESNP 976
Cdd:pfam00041 78 GGGEGPP 84
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1433-1505 |
1.67e-13 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 67.64 E-value: 1.67e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767957307 1433 DSPRDLTATEVQSETALLTWRPPRAS-----VTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNG 1505
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNG 79
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1075-1154 |
2.07e-13 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 67.05 E-value: 2.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1075 PELENLTVTEVGWDGLRLNWTAADQ---AYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGY 1151
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPDgngPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
...
gi 767957307 1152 RTP 1154
Cdd:pfam00041 81 EGP 83
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1256-1335 |
2.24e-13 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 67.05 E-value: 2.24e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1256 GSPKEVIFSDITENSATVSWRAPT---AQVESFRITYVPITGGTPS-MVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFE 1331
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWnEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....
gi 767957307 1332 ESEP 1335
Cdd:pfam00041 81 EGPP 84
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
986-1064 |
2.42e-13 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 67.05 E-value: 2.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 986 DTPKDLQVSETAETSLTLLWKTPL---AKFDRYRLNYSLPTGQ--WVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRH 1060
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....
gi 767957307 1061 KSKP 1064
Cdd:pfam00041 81 EGPP 84
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
894-978 |
2.92e-13 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 67.14 E-value: 2.92e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 894 DAPRNLRRVSQTDNSITLEW---RNGKAAIDSYRIKYAPISGGDHAEVDVPKSQqaTTKTTLTGLRPGTEYGIGVSAVKE 970
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWtppEDDGGPITGYVVEYREKGSGDWKEVEVTPGS--ETSYTLTGLKPGTEYEFRVRAVNG 79
|
....*...
gi 767957307 971 DKESNPAT 978
Cdd:cd00063 80 GGESPPSE 87
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1256-1342 |
4.94e-13 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 66.37 E-value: 4.94e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1256 GSPKEVIFSDITENSATVSWRAPT---AQVESFRITYVPITGGTPSMVTV-DGTKTQTRLVKLIPGVEYLVSIIAMKGFE 1331
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVtPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 767957307 1332 ESEPV-SGSFTT 1342
Cdd:cd00063 82 ESPPSeSVTVTT 93
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
804-884 |
1.20e-12 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 65.13 E-value: 1.20e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 804 DAPSQIEVKDVTDTTALITWFKPL---AEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDM 880
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....
gi 767957307 881 SSNP 884
Cdd:pfam00041 81 EGPP 84
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1433-1518 |
1.68e-12 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 64.83 E-value: 1.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1433 DSPRDLTATEVQSETALLTWRPPR---ASVTGYLLVYESVD-GTVKEVIVGP-DTTSYSLADLSPSTHYTAKIQALNGPL 1507
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGsGDWKEVEVTPgSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 767957307 1508 RSNMIQTI-FTT 1518
Cdd:cd00063 82 ESPPSESVtVTT 93
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
986-1065 |
1.73e-12 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 64.83 E-value: 1.73e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 986 DTPKDLQVSETAETSLTLLWKTPL---AKFDRYRLNYS-LPTGQWVGVQLPR-NTTSYVLRGLEPGQEYNVLLTAEKGRH 1060
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYReKGSGDWKEVEVTPgSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
....*
gi 767957307 1061 KSKPA 1065
Cdd:cd00063 82 ESPPS 86
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
713-793 |
6.47e-12 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.82 E-value: 6.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 713 PAPEGLKFKSIKETSVEVEWDP---LDIAFETWEIIFRNMNKEDEgEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNN 789
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPppdGNGPITGYEVEYRPKNSGEP-WNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79
|
....
gi 767957307 790 TRGP 793
Cdd:pfam00041 80 GEGP 83
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
667-988 |
6.99e-12 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 70.42 E-value: 6.99e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 667 QFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIP---VSARVATYLP-APEGLKFKSIKETSVEVEWDPLDIAFETW 742
Cdd:COG3401 184 SLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPsneVSVTTPTTPPsAPTGLTATADTPGSVTLSWDPVTESDATG 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 743 EIIFRNMNKEDEGE-ITKSlrrPETSYRQTGLAPGQEYE--ISLHIVKNNTRGP-GLKRVTT--TRLDAPSQIEVKDVTD 816
Cdd:COG3401 264 YRVYRSNSGDGPFTkVATV---TTTSYTDTGLTNGTTYYyrVTAVDAAGNESAPsNVVSVTTdlTPPAAPSGLTATAVGS 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 817 TTALITWFKPLaeiDGIELTYGI---KDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGD-MSSNPAKETFTTG 892
Cdd:COG3401 341 SSITLSWTASS---DADVTGYNVyrsTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVDAAgNESAPSEEVSATT 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 893 LDAPR-----------NLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEY 961
Cdd:COG3401 418 ASAASgesltasvdavPLTDVAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGSLV 497
|
330 340
....*....|....*....|....*..
gi 767957307 962 GIGVSAVKEDKESNPATINAATELDTP 988
Cdd:COG3401 498 GGSGASSVTNSVSVIGASAAAAVGGAP 524
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1169-1241 |
1.20e-11 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.05 E-value: 1.20e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767957307 1169 GEVVVAEVGWDALKLNWTAPE---GAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQD 1241
Cdd:pfam00041 4 SNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
804-891 |
1.32e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 62.51 E-value: 1.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 804 DAPSQIEVKDVTDTTALITWFKPL---AEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDM 880
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 767957307 881 SSNPAK-ETFTT 891
Cdd:cd00063 82 ESPPSEsVTVTT 93
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
986-1062 |
1.65e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 61.86 E-value: 1.65e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 986 DTPKDLQVSETAETSLTLLWKTP-----LAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRH 1060
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPpddgiTGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 767957307 1061 KS 1062
Cdd:smart00060 82 EG 83
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1210-1505 |
2.49e-11 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 68.49 E-value: 2.49e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1210 NLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTAMGSPKEVIFSDITENSATVSW---RAPTAQVESFR 1286
Cdd:COG3401 4 SYLTSLDAGIAASAAANTAVNALSKAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTggrAGTTSGVAAVA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1287 ITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQP 1366
Cdd:COG3401 84 VAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1367 AIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFA---EKGPQKSSTITA-KFTTDLDSPRDLTATE 1442
Cdd:COG3401 164 AGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAAtdtGGESAPSNEVSVtTPTTPPSAPTGLTATA 243
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767957307 1443 VQSETALLTWRP-PRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNG 1505
Cdd:COG3401 244 DTPGSVTLSWDPvTESDATGYRVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDA 307
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1347-1417 |
2.06e-10 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 58.58 E-value: 2.06e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767957307 1347 PSGLVTANITDSEALARWQPA---IATVDSYVISY--TGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKG 1417
Cdd:pfam00041 3 PSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYrpKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
624-779 |
4.85e-10 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 64.25 E-value: 4.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 624 SPPKDLVVTEVTEETVNLAWD--NEMRVTEYLVVYTPTHEGGLEmqfRVPGDQTSTII-QELEPGVEYFIRVFAI----L 696
Cdd:COG3401 234 SAPTGLTATADTPGSVTLSWDpvTESDATGYRVYRSNSGDGPFT---KVATVTTTSYTdTGLTNGTTYYYRVTAVdaagN 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 697 ENKKSIPVSARVATYLP-APEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDE-GEITKSLRrpETSYRQTGLA 774
Cdd:COG3401 311 ESAPSNVVSVTTDLTPPaAPSGLTATAVGSSSITLSWTASSDADVTGYNVYRSTSGGGTyTKIAETVT--TTSYTDTGLT 388
|
....*
gi 767957307 775 PGQEY 779
Cdd:COG3401 389 PGTTY 393
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
894-974 |
5.82e-10 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 57.24 E-value: 5.82e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 894 DAPRNLRRVSQTDNSITLEWR-----NGKAAIDSYRIKYAPiSGGDHAEVDVPKSqqaTTKTTLTGLRPGTEYGIGVSAV 968
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEpppddGITGYIVGYRVEYRE-EGSEWKEVNVTPS---STSYTLTGLKPGTEYEFRVRAV 77
|
....*.
gi 767957307 969 KEDKES 974
Cdd:smart00060 78 NGAGEG 83
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
804-882 |
1.93e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 56.08 E-value: 1.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 804 DAPSQIEVKDVTDTTALITWFKPLAE-IDGIELTYGIKDVPGDR--TTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDM 880
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPDDgITGYIVGYRVEYREEGSewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 767957307 881 SS 882
Cdd:smart00060 82 EG 83
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1256-1333 |
3.95e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 54.93 E-value: 3.95e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1256 GSPKEVIFSDITENSATVSWRAPT-AQVESFRITYVPITGGTPS---MVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFE 1331
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPdDGITGYIVGYRVEYREEGSewkEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 767957307 1332 ES 1333
Cdd:smart00060 82 EG 83
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
624-695 |
1.70e-08 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 53.19 E-value: 1.70e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767957307 624 SPPKDLVVTEVTEETVNLAW----DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAI 695
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWtpppDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAV 76
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
624-710 |
1.88e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 53.27 E-value: 1.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 624 SPPKDLVVTEVTEETVNLAW----DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENK 699
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWtppeDDGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|.
gi 767957307 700 KSIPVSARVAT 710
Cdd:cd00063 82 ESPPSESVTVT 92
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1345-1421 |
4.08e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 52.23 E-value: 4.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1345 DGPSGLVTANITDSEALARWQ-PAIATVDSYVISYTGEKVPEITR----TVSGNTVEYALTDLEPATEYTLRIFAEKGPQ 1419
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEpPPDDGITGYIVGYRVEYREEGSEwkevNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 767957307 1420 KS 1421
Cdd:smart00060 82 EG 83
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1345-1430 |
7.58e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 51.73 E-value: 7.58e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1345 DGPSGLVTANITDSEALARWQPA---IATVDSYVISY--TGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQ 1419
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPeddGGPITGYVVEYreKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 767957307 1420 KS-STITAKFTT 1430
Cdd:cd00063 82 ESpPSESVTVTT 93
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
713-801 |
1.12e-07 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 51.34 E-value: 1.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 713 PAPEGLKFKSIKETSVEVEWDPLD---IAFETWEIIFRNMNKEDEGEITKSlRRPETSYRQTGLAPGQEYEISLHIVKNN 789
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVT-PGSETSYTLTGLKPGTEYEFRVRAVNGG 80
|
90
....*....|..
gi 767957307 790 TRGPGLKRVTTT 801
Cdd:cd00063 81 GESPPSESVTVT 92
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
713-794 |
2.34e-07 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 49.92 E-value: 2.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 713 PAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRP--ETSYRQTGLAPGQEYEISLHIVknNT 790
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPDDGITGYIVGYRVEYREEGSEWKEVNVTpsSTSYTLTGLKPGTEYEFRVRAV--NG 79
|
....
gi 767957307 791 RGPG 794
Cdd:smart00060 80 AGEG 83
|
|
| GGGWT_bact |
NF040941 |
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, ... |
1535-1568 |
4.79e-07 |
|
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, describes a conserved domain found in eukaryotic proteins such as fibrinogen beta and gamma chains, fincolin, and angiopoietin. This model describes a small homology domain, about 46 amino acids long, found in the PF00147 homology region of those proteins but also as a much shorter homology domain in bacterial proteins that may lack homology to those proteins, or to each other, outside this region. The signature motif, at the C-terminus of this domain, is YCDxTTDGGGWxLV.
Pssm-ID: 468872 [Multi-domain] Cd Length: 46 Bit Score: 47.94 E-value: 4.79e-07
10 20 30
....*....|....*....|....*....|....*
gi 767957307 1535 NGDTTSGLYTIYLNGD-KAEALEVFCDMTSDGGGW 1568
Cdd:NF040941 9 GPSAPSGVYWIDPDGMgGLAPFQVYCDMTTDGGGW 43
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1078-1162 |
3.31e-06 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 47.11 E-value: 3.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1078 ENLTVTEVGWDGLRLNWTAADQAY---EHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYR-T 1153
Cdd:cd00063 5 TNLRVTDVTSTSVTLSWTPPEDDGgpiTGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGEsP 84
|
....*....
gi 767957307 1154 PVLSAEAST 1162
Cdd:cd00063 85 PSESVTVTT 93
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
408-435 |
4.80e-06 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 44.60 E-value: 4.80e-06
10 20
....*....|....*....|....*...
gi 767957307 408 CPNGCSGHGRCVNGQCVCDEGYTGEDCS 435
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1171-1253 |
1.81e-05 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 44.79 E-value: 1.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1171 VVVAEVGWDALKLNWTAPE---GAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPL 1247
Cdd:cd00063 7 LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPS 86
|
....*.
gi 767957307 1248 SVEVLT 1253
Cdd:cd00063 87 ESVTVT 92
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
501-528 |
2.11e-05 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 42.67 E-value: 2.11e-05
10 20
....*....|....*....|....*...
gi 767957307 501 CPRDCSNRGLCVDGQCVCEDGFTGPDCA 528
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
190-217 |
3.15e-05 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 42.29 E-value: 3.15e-05
10 20
....*....|....*....|....*...
gi 767957307 190 CPGNCHLRGRCIDGQCICDDGFTGEDCS 217
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1171-1240 |
4.44e-05 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 43.37 E-value: 4.44e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767957307 1171 VVVAEVGWDALKLNWTAPEGAYEYFFI---QVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQ 1240
Cdd:smart00060 7 LRVTDVTSTSVTLSWEPPPDDGITGYIvgyRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNG 79
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1078-1147 |
4.52e-05 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 43.37 E-value: 4.52e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767957307 1078 ENLTVTEVGWDGLRLNWTA-ADQAYEHFIIQVQEANKVEAAR--NLTVPGSLRAVDIPGLKAATPYTVSIYGV 1147
Cdd:smart00060 5 SNLRVTDVTSTSVTLSWEPpPDDGITGYIVGYRVEYREEGSEwkEVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
624-695 |
1.19e-04 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 42.22 E-value: 1.19e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767957307 624 SPPKDLVVTEVTEETVNLAWD------NEMRVTEYLVVYTPthEGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAI 695
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEpppddgITGYIVGYRVEYRE--EGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77
|
|
| COG4733 |
COG4733 |
Phage-related protein, tail protein J [Mobilome: prophages, transposons]; |
868-1239 |
2.51e-04 |
|
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
Pssm-ID: 443767 [Multi-domain] Cd Length: 978 Bit Score: 46.09 E-value: 2.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 868 EYEVSL--ISRRGDMSSNPAKETFTTGLD-----APRNLRrVSQTDNSITLEWRNGK-AAIDSYRIKYAPisGGDHAEVD 939
Cdd:COG4733 598 DYEVRVraINALGVSSAWAASSETTVTGKtapppAPTGLT-ATGGLGGITLSWSFPVdADTLRTEIRYST--TGDWASAT 674
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 940 VPKSQQATTKTTLTGLRPGTEYGIGVSAVkeDKESN--PATINAATELDTPKDLQVSETAETsltllwKTPLAKfdryRL 1017
Cdd:COG4733 675 VAQALYPGNTYTLAGLKAGQTYYYRARAV--DRSGNvsAWWVSGQASADAAGILDAITGQIL------ETELGQ----EL 742
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1018 NYSLPTGQWVGVQLPRNTTsyvlrglepgqeynvlLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGLRLNWTAA 1097
Cdd:COG4733 743 DAIIQNATVAEVVAATVTD----------------VTAQIDTAVLFAGVATAAAIGAEARVAATVAESATAAAATGTAAD 806
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1098 DQAYEH-FIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEV 1176
Cdd:COG4733 807 AAGDASgGVTAGTSGTTGAGDTAASTTRVAAAVVLAGVVVYGDAIIESGNTGDIVATGDIASAAAGAVATTVSGTTAADV 886
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767957307 1177 GWDALKLNWTAPEGAYEY--FFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVT 1239
Cdd:COG4733 887 SAVADSTAASLTAIVIAAttIIDAIGDGTTREPAGDIGASGGAQGFAVTIVGSFDGAGAVATVDA 951
|
|
| COG3979 |
COG3979 |
Chitodextrinase [Carbohydrate transport and metabolism]; |
1347-1717 |
2.60e-04 |
|
Chitodextrinase [Carbohydrate transport and metabolism];
Pssm-ID: 443178 [Multi-domain] Cd Length: 369 Bit Score: 45.53 E-value: 2.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1347 PSGLVTANITDSEALARWQPAIAT--VDSYVISYTGEKVpeitRTVSGNTvEYALTDLEPATEYTLrifaekgpqkssTI 1424
Cdd:COG3979 6 PTGLTASNVTSSSVSLSWDASTDNvgVTGYDVYRGGDQV----ATVTGLT-AWTVTGLTPGTEYTF------------TV 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1425 TAKFTTDLDSPR--DLTATEVQSETALLTWRPPRASVTGYllvyeSVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQA 1502
Cdd:COG3979 69 GACDAAGNVSAAsgTSTAMFGGSSTTLGSAEGVADTSGNL-----AASGAFFGVTTPPTPSSTLVVDGTTTVNAAATANG 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1503 LNGplRSNMIQTIFTTIGLLYPFPKDcsQAMLNGDTTSGLYTIYLNGDKAEALEVFC------DMTSDGGGWIVFLRRKN 1576
Cdd:COG3979 144 GTG--GSGGTTTIITTGVEGGGGSKT--AQSLNAITAAGTAALNGGVVGGADEVLTCsavkddGSGGAGAGNTYWALNTL 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1577 G------RENFYQNWKAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYKLKVEG 1650
Cdd:COG3979 220 GvsdtpsGTTATGGTVGITSAYGAGVSGNAAVNVNAGFVVGNVGGAAGNTGTTSGTATSDAATNDVGDAAVTGLNDGAAN 299
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767957307 1651 YSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGDNNHSQGVNWFHW 1717
Cdd:COG3979 300 GPTGGYGATGTTVAGAAGVGGTKSGTGALGLSGAGGAGAAVSGTATGDDDAGADDSTAGVSGAGSTT 366
|
|
| fn3_2 |
pfam16893 |
Fibronectin type III domain; This fibronectin type III domain is found in fungal chitin ... |
713-783 |
3.85e-04 |
|
Fibronectin type III domain; This fibronectin type III domain is found in fungal chitin biosynthesis protein CHS5 where, together with the neighbouring BRCT domain (pfam00533), it binds to the Arf1 GTPase.
Pssm-ID: 435634 Cd Length: 89 Bit Score: 41.03 E-value: 3.85e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767957307 713 PAPEGLKFKSIKETSVEVEWDPLDIAFETWE--IIFRNMNKedEGEITKSLRRpeTSYRQTGLAPGQEYEISL 783
Cdd:pfam16893 3 PKAPVLKVRNVTQTSVVLEWDPLELGTAKLKslDLYRNGQR--LGVIPNPLTN--TSTKLSGLSVDTEYTFQL 71
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
594-621 |
5.38e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 38.82 E-value: 5.38e-04
10 20
....*....|....*....|....*...
gi 767957307 594 CPSDCNNLGQCVSGRCICNEGYSGEDCS 621
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| COG3979 |
COG3979 |
Chitodextrinase [Carbohydrate transport and metabolism]; |
895-1242 |
1.23e-03 |
|
Chitodextrinase [Carbohydrate transport and metabolism];
Pssm-ID: 443178 [Multi-domain] Cd Length: 369 Bit Score: 43.22 E-value: 1.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 895 APRNLRRVSQTDNSITLEWRngkAAIDSYRIKYAPI-SGGDhaEVDVPKSQqatTKTTLTGLRPGTEYGIGVSAVkeDKE 973
Cdd:COG3979 5 APTGLTASNVTSSSVSLSWD---ASTDNVGVTGYDVyRGGD--QVATVTGL---TAWTVTGLTPGTEYTFTVGAC--DAA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 974 SN----PATINAATELDTPKDLQVSETAETSLTllWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEY 1049
Cdd:COG3979 75 GNvsaaSGTSTAMFGGSSTTLGSAEGVADTSGN--LAASGAFFGVTTPPTPSSTLVVDGTTTVNAAATANGGTGGSGGTT 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1050 NVLLTAEKGRHKSKPARVKASTEQAPelenlTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAV 1129
Cdd:COG3979 153 TIITTGVEGGGGSKTAQSLNAITAAG-----TAALNGGVVGGADEVLTCSAVKDDGSGGAGAGNTYWALNTLGVSDTPSG 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1130 DIPGLKAATPYTVSIYGVIQGYRTPV--LSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEA 1207
Cdd:COG3979 228 TTATGGTVGITSAYGAGVSGNAAVNVnaGFVVGNVGGAAGNTGTTSGTATSDAATNDVGDAAVTGLNDGAANGPTGGYGA 307
|
330 340 350
....*....|....*....|....*....|....*
gi 767957307 1208 AQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDF 1242
Cdd:COG3979 308 TGTTVAGAAGVGGTKSGTGALGLSGAGGAGAAVSG 342
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
439-466 |
1.38e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.66 E-value: 1.38e-03
10 20
....*....|....*....|....*...
gi 767957307 439 CPNDCHSRGRCVEGKCVCEQGFKGYDCS 466
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
377-403 |
1.42e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.66 E-value: 1.42e-03
10 20
....*....|....*....|....*..
gi 767957307 377 CPADCHNRGRCVDGRCECDDGFTGADC 403
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
380-403 |
1.57e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 37.33 E-value: 1.57e-03
10 20
....*....|....*....|....*.
gi 767957307 380 DCHNRGRCVD--GRCECDDGFTGADC 403
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
412-434 |
2.11e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 36.94 E-value: 2.11e-03
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
470-496 |
2.21e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.28 E-value: 2.21e-03
10 20
....*....|....*....|....*..
gi 767957307 470 CPNDCHQHGRCVNGMCVCDDGYTGEDC 496
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
346-373 |
2.24e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.28 E-value: 2.24e-03
10 20
....*....|....*....|....*...
gi 767957307 346 CPHACHTQGRCEEGQCVCDEGFAGVDCS 373
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
473-496 |
3.06e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 36.56 E-value: 3.06e-03
10 20
....*....|....*....|....*.
gi 767957307 473 DCHQHGRCVN--GMCVCDDGYTGEDC 496
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
563-589 |
3.88e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 36.51 E-value: 3.88e-03
10 20
....*....|....*....|....*..
gi 767957307 563 CPSDCHGQGRCVDGQCICHEGFTGLDC 589
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| COG4733 |
COG4733 |
Phage-related protein, tail protein J [Mobilome: prophages, transposons]; |
1170-1412 |
3.95e-03 |
|
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
Pssm-ID: 443767 [Multi-domain] Cd Length: 978 Bit Score: 42.24 E-value: 3.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1170 EVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADT---------VEAAQNLTVPGGLRSTDlPGLKAAT-HYTITIRGVT 1239
Cdd:COG4733 452 ARTVQSVAGRTLTVSTAYSETPEAGAVWAFGPDELetqlfrvvsIEENEDGTYTITAVQHA-PEKYAAIdAGAFDDVPPQ 530
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1240 QDFSTTPLSVEVltamgspkEVIFSDITENSATVSWRAPTAQVeSFRITYVPitgGTPSMVTVDGTKTQTRLVKLIPGVE 1319
Cdd:COG4733 531 WPPVNVTTSESL--------SVVAQGTAVTTLTVSWDAPAGAV-AYEVEWRR---DDGNWVSVPRTSGTSFEVPGIYAGD 598
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767957307 1320 YLVSIIAMKGFEESEPVSGSFTTALDG-------PSGLvTANITDSEALARW-QPAIATVDSYVISYTGEKVPEIT--RT 1389
Cdd:COG4733 599 YEVRVRAINALGVSSAWAASSETTVTGktapppaPTGL-TATGGLGGITLSWsFPVDADTLRTEIRYSTTGDWASAtvAQ 677
|
250 260
....*....|....*....|...
gi 767957307 1390 VSGNTVEYALTDLEPATEYTLRI 1412
Cdd:COG4733 678 ALYPGNTYTLAGLKAGQTYYYRA 700
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
504-527 |
8.10e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 35.40 E-value: 8.10e-03
10 20
....*....|....*....|....*.
gi 767957307 504 DCSNRGLCVD--GQCVCEDGFTGPDC 527
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
535-558 |
8.34e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 35.40 E-value: 8.34e-03
10 20
....*....|....*....|....*.
gi 767957307 535 DCHGQGRCVN--GQCVCHEGFMGKDC 558
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| |
