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Conserved domains on  [gi|767926294|ref|XP_011510950|]
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target of Nesh-SH3 isoform X25 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 732-1229 4.03e-16

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 84.99  E-value: 4.03e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  732 SAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVP-ATILEPV-------------LRTEASG-------TTAAPKVPQR--- 787
Cdd:PHA03247 2490 FAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPdEPVGEPVhprmltwirgleeLASDDAGdpppplpPAAPPAAPDRsvp 2569

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  788 THRPHPKPKTTLSPEELQTELVP---ATIFEPVSPIKEAPGTTfvPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPK 864
Cdd:PHA03247 2570 PPRPAPRPSEPAVTSRARRPDAPpqsARPRAPVDDRGDPRGPA--PPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVP 2647

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  865 TtpsPQAPETKPVPATVLEPVTLRPEASTTLASKTSQRTRRPRLRTKTTP-----RPEAPESKPVPtaelkpvtlRTETW 939
Cdd:PHA03247 2648 P---PERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSltslaDPPPPPPTPEP---------APHAL 2715

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  940 VT-TQAPKTSQRTRRPRPKTKTTPSPevpqtklvPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTR 1018
Cdd:PHA03247 2716 VSaTPLPPGPAAARQASPALPAAPAP--------PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPA 2787

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1019 RPRPRPKTTS--SPEVPQNKSVSVTGFEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESqPVSDVLESVTLSTES 1096
Cdd:PHA03247 2788 VASLSESRESlpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP-LGGSVAPGGDVRRRP 2866

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1097 PKETIAPAKTDYVYPTAKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPK 1176
Cdd:PHA03247 2867 PSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767926294 1177 TSPRPRIPQTQPVPK------VPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVS 1229
Cdd:PHA03247 2947 TDPAGAGEPSGAVPQpwlgalVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVS 3005
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 432-934 1.30e-12

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 73.43  E-value: 1.30e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  432 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE--RTTSAGTITPKISKSPEPTWTT 509
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGdpRGPAPPSPLPPDTHAPDPPPPS 2630

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  510 PAPGKTQfiSLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVP 589
Cdd:PHA03247 2631 PSPAANE--PDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTP 2708

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  590 KSKPalePATIQPEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPP--KQLLPKPQTTAEPD--MPPTKSVSEPVPFETE 665
Cdd:PHA03247 2709 EPAP---HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPggPARPARPPTTAGPPapAPPAAPAAGPPRRLTR 2785

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  666 APSMTIVPTTDIEP-----------VTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDfGPITPGtssAP 734
Cdd:PHA03247 2786 PAVASLSESRESLPspwdpadppaaVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG-GSVAPG---GD 2861

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  735 TTTTKRTRRPHPKPKTTPHPEV-----PQTKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEE------ 803
Cdd:PHA03247 2862 VRRRPPSRSPAAKPAAPARPPVrrlarPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPpprpqp 2941

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  804 -LQTELVPATIFEPvSPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAP-----ETKPV 877
Cdd:PHA03247 2942 pLAPTTDPAGAGEP-SGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSlalheETDPP 3020

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767926294  878 PATVLEpvTLRPEASTTLASKTSQRTRRPRLRTKTTPRPEAPESKPVPTAELKPVTL 934
Cdd:PHA03247 3021 PVSLKQ--TLWPPDDTEDSDADSLFDSDSERSDLEALDPLPPEPHDPFAHEPDPATP 3075
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1511-1602 1.16e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 56.74  E-value: 1.16e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1511 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 1588
Cdd:cd00063     2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                          90
                  ....*....|....
gi 767926294 1589 LGEGPVSNTVAFST 1602
Cdd:cd00063    80 GGESPPSESVTVTT 93
PRK10263 super family cl35903
DNA translocase FtsK; Provisional
 1112-1364 1.04e-05

DNA translocase FtsK; Provisional


The actual alignment was detected with superfamily member PRK10263:

Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 50.85  E-value: 1.04e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1112 TAKAPLW--PEEPKTEVVESITYVSEPPETTLETSPLPSqsitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPV 1189
Cdd:PRK10263  327 TTATQSWaaPVEPVTQTPPVASVDVPPAQPTVAWQPVPG-----PQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPV 401

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1190 PkvPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPVLQPVTfrfEPPKTTIAPLETRGiPFIPMISPSPsq 1269
Cdd:PRK10263  402 Q--PQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA---EEQQSTFAPQSTYQ-TEQTYQQPAA-- 473

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1270 eelQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD---------KPHIRPVLNRTTTRPTRPKPS-- 1338
Cdd:PRK10263  474 ---QEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRARereqlaawyQPIPEPVKEPEPIKSSLKAPSva 550

                         250       260       270
                  ....*....|....*....|....*....|..
gi 767926294 1339 ------GMPSGNGVGTGVKQAPRPSGADRNVS 1364
Cdd:PRK10263  551 avppveAAAAVSPLASGVKKATLATGAAATVA 582
FN3 super family cl27307
Fibronectin type 3 domain [General function prediction only];
1328-1607 5.30e-04

Fibronectin type 3 domain [General function prediction only];


The actual alignment was detected with superfamily member COG3401:

Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 44.61  E-value: 5.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1328 TTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGI 1407
Cdd:COG3401    48 TKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGTATT 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1408 ISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNS--- 1484
Cdd:COG3401   128 ATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTyyy 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1485 -PCSITDSVKRFPKEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEvISRENGSfSGKNKSIQMT 1563
Cdd:COG3401   208 rVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTESDATGYR-VYRSNSG-DGPFTKVATV 282

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 767926294 1564 NQTFSTVENLKPNTSYEFQVKPKNPLG-EGPVSNTVAFSTESADP 1607
Cdd:COG3401   283 TTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
FN3 super family cl21522
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 123-202 6.13e-04

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


The actual alignment was detected with superfamily member pfam00041:

Pssm-ID: 473895 [Multi-domain]  Cd Length: 85  Bit Score: 40.48  E-value: 6.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   123 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPND-RFYTIRYREKDKEKKWIFQICPATET--IVENLKPNTVYEF 199
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71


                   ...
gi 767926294   200 GVK 202
Cdd:pfam00041   72 RVQ 74
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 732-1229 4.03e-16

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 84.99  E-value: 4.03e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  732 SAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVP-ATILEPV-------------LRTEASG-------TTAAPKVPQR--- 787
Cdd:PHA03247 2490 FAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPdEPVGEPVhprmltwirgleeLASDDAGdpppplpPAAPPAAPDRsvp 2569

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  788 THRPHPKPKTTLSPEELQTELVP---ATIFEPVSPIKEAPGTTfvPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPK 864
Cdd:PHA03247 2570 PPRPAPRPSEPAVTSRARRPDAPpqsARPRAPVDDRGDPRGPA--PPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVP 2647

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  865 TtpsPQAPETKPVPATVLEPVTLRPEASTTLASKTSQRTRRPRLRTKTTP-----RPEAPESKPVPtaelkpvtlRTETW 939
Cdd:PHA03247 2648 P---PERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSltslaDPPPPPPTPEP---------APHAL 2715

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  940 VT-TQAPKTSQRTRRPRPKTKTTPSPevpqtklvPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTR 1018
Cdd:PHA03247 2716 VSaTPLPPGPAAARQASPALPAAPAP--------PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPA 2787

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1019 RPRPRPKTTS--SPEVPQNKSVSVTGFEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESqPVSDVLESVTLSTES 1096
Cdd:PHA03247 2788 VASLSESRESlpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP-LGGSVAPGGDVRRRP 2866

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1097 PKETIAPAKTDYVYPTAKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPK 1176
Cdd:PHA03247 2867 PSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767926294 1177 TSPRPRIPQTQPVPK------VPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVS 1229
Cdd:PHA03247 2947 TDPAGAGEPSGAVPQpwlgalVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVS 3005
PHA03247 PHA03247
large tegument protein UL36; Provisional
 432-934 1.30e-12

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 73.43  E-value: 1.30e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  432 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE--RTTSAGTITPKISKSPEPTWTT 509
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGdpRGPAPPSPLPPDTHAPDPPPPS 2630

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  510 PAPGKTQfiSLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVP 589
Cdd:PHA03247 2631 PSPAANE--PDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTP 2708

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  590 KSKPalePATIQPEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPP--KQLLPKPQTTAEPD--MPPTKSVSEPVPFETE 665
Cdd:PHA03247 2709 EPAP---HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPggPARPARPPTTAGPPapAPPAAPAAGPPRRLTR 2785

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  666 APSMTIVPTTDIEP-----------VTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDfGPITPGtssAP 734
Cdd:PHA03247 2786 PAVASLSESRESLPspwdpadppaaVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG-GSVAPG---GD 2861

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  735 TTTTKRTRRPHPKPKTTPHPEV-----PQTKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEE------ 803
Cdd:PHA03247 2862 VRRRPPSRSPAAKPAAPARPPVrrlarPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPpprpqp 2941

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  804 -LQTELVPATIFEPvSPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAP-----ETKPV 877
Cdd:PHA03247 2942 pLAPTTDPAGAGEP-SGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSlalheETDPP 3020

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767926294  878 PATVLEpvTLRPEASTTLASKTSQRTRRPRLRTKTTPRPEAPESKPVPTAELKPVTL 934
Cdd:PHA03247 3021 PVSLKQ--TLWPPDDTEDSDADSLFDSDSERSDLEALDPLPPEPHDPFAHEPDPATP 3075
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1511-1602 1.16e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 56.74  E-value: 1.16e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1511 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 1588
Cdd:cd00063     2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                          90
                  ....*....|....
gi 767926294 1589 LGEGPVSNTVAFST 1602
Cdd:cd00063    80 GGESPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 1512-1592 1.59e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 50.31  E-value: 1.59e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   1512 PPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV-ISRENGSFSGKNKSIQMTNQTFS-TVENLKPNTSYEFQVKPKNPL 1589
Cdd:smart00060    3 PPSNLRVTDVT--STSVTLSWEPPPDDGITGYIVgYRVEYREEGSEWKEVNVTPSSTSyTLTGLKPGTEYEFRVRAVNGA 80


                    ...
gi 767926294   1590 GEG 1592
Cdd:smart00060   81 GEG 83
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 1112-1364 1.04e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 50.85  E-value: 1.04e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1112 TAKAPLW--PEEPKTEVVESITYVSEPPETTLETSPLPSqsitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPV 1189
Cdd:PRK10263  327 TTATQSWaaPVEPVTQTPPVASVDVPPAQPTVAWQPVPG-----PQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPV 401

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1190 PkvPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPVLQPVTfrfEPPKTTIAPLETRGiPFIPMISPSPsq 1269
Cdd:PRK10263  402 Q--PQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA---EEQQSTFAPQSTYQ-TEQTYQQPAA-- 473

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1270 eelQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD---------KPHIRPVLNRTTTRPTRPKPS-- 1338
Cdd:PRK10263  474 ---QEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRARereqlaawyQPIPEPVKEPEPIKSSLKAPSva 550

                         250       260       270
                  ....*....|....*....|....*....|..
gi 767926294 1339 ------GMPSGNGVGTGVKQAPRPSGADRNVS 1364
Cdd:PRK10263  551 avppveAAAAVSPLASGVKKATLATGAAATVA 582
fn3 pfam00041
Fibronectin type III domain;
1512-1595 4.59e-05

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 43.56  E-value: 4.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  1512 PPTNLTVVTVEgcPSFVILDWEKP--LNDTVTEYEVISRENGSFSGKNkSIQMTNQTFS-TVENLKPNTSYEFQVKPKNP 1588
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPpdGNGPITGYEVEYRPKNSGEPWN-EITVPGTTTSvTLTGLKPGTEYEVRVQAVNG 78


                   ....*..
gi 767926294  1589 LGEGPVS 1595
Cdd:pfam00041   79 GGEGPPS 85
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1328-1607 5.30e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 44.61  E-value: 5.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1328 TTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGI 1407
Cdd:COG3401    48 TKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGTATT 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1408 ISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNS--- 1484
Cdd:COG3401   128 ATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTyyy 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1485 -PCSITDSVKRFPKEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEvISRENGSfSGKNKSIQMT 1563
Cdd:COG3401   208 rVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTESDATGYR-VYRSNSG-DGPFTKVATV 282

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 767926294 1564 NQTFSTVENLKPNTSYEFQVKPKNPLG-EGPVSNTVAFSTESADP 1607
Cdd:COG3401   283 TTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
fn3 pfam00041
Fibronectin type III domain;
123-202 6.13e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 40.48  E-value: 6.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   123 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPND-RFYTIRYREKDKEKKWIFQICPATET--IVENLKPNTVYEF 199
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71


                   ...
gi 767926294   200 GVK 202
Cdd:pfam00041   72 RVQ 74
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 124-202 6.30e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 40.29  E-value: 6.30e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294    124 PLQLVVGTLTPSSVFLSWgflinphhdwtLPSHCPNDRFYTIRYREKDKEKKWIFQICPA----TETIVENLKPNTVYEF 199
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSW-----------EPPPDDGITGYIVGYRVEYREEGSEWKEVNVtpssTSYTLTGLKPGTEYEF 72


                    ...
gi 767926294    200 GVK 202
Cdd:smart00060   73 RVR 75
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1506-1650 6.78e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 44.61  E-value: 6.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1506 TSPPQnPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV--ISRENGSFSGKNKSIqmtNQTFSTVENLKPNTSYEFQV 1583
Cdd:COG3401   324 LTPPA-APSGLTATAVG--SSSITLSWTASSDADVTGYNVyrSTSGGGTYTKIAETV---TTTSYTDTGLTPGTTYYYKV 397

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767926294 1584 KPKNPLG-EGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVG 1650
Cdd:COG3401   398 TAVDAAGnESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTG 465
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 889-1215 2.07e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 42.64  E-value: 2.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   889 PEASTTLASKTSQRT-RRPRLRTKTTPRPEAPESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPSPEVP 967
Cdd:pfam17823   66 APAPVTLTKGTSAAHlNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSEAFSAP 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   968 QTKlVPSTdlePGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPKTTS----SPEVPQNKSVSVTGF 1043
Cdd:pfam17823  146 RAA-ACRA---NASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSApatlTPARGISTAATATGH 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  1044 EPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESQPVSDVLESVTLSTESP-KETIAPAKTDYVYPTAKAPLWPEEP 1122
Cdd:pfam17823  222 PAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPhARRLSPAKHMPSDTMARNPAAPMGA 301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  1123 KTEVVESITYVSEPPETTlETSPLPSQSITLPSPDEPQ-----------TEPAPKQTPRAPPKP--KTSPRPRI----PQ 1185
Cdd:pfam17823  302 QAQGPIIQVSTDQPVHNT-AGEPTPSPSNTTLEPNTPKsvastnlavvtTTKAQAKEPSASPVPvlHTSMIPEVeatsPT 380

                          330       340       350
                   ....*....|....*....|....*....|
gi 767926294  1186 TQPVPKVPQRVTAKPKTSPSPEVSYTTPAP 1215
Cdd:pfam17823  381 TQPSPLLPTQGAAGPGILLAPEQVATEATA 410
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 123-202 3.01e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.63  E-value: 3.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  123 KPLQLVVGTLTPSSVFLSWgfliNPHHDWTLPSHcpndrFYTIRYREKDKE--KKWIFQICPATETIVENLKPNTVYEFG 200
Cdd:cd00063     3 PPTNLRVTDVTSTSVTLSW----TPPEDDGGPIT-----GYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFR 73


                  ..
gi 767926294  201 VK 202
Cdd:cd00063    74 VR 75
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 408-793 8.27e-03

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 40.91  E-value: 8.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   408 QPQTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE 487
Cdd:pfam03154  170 QPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   488 RTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAprKT 567
Cdd:pfam03154  250 QPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRI--HT 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   568 KRPGRRPRPRPRPKTTPSPEVPKSKPALEPATIQPEPLVPTTASKpsERPKTTHRPDAPQIQPGSKPPKQLlpKPQTTAE 647
Cdd:pfam03154  328 PPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSH--KHPPHLSGPSPFQMNSNLPPPPAL--KPLSSLS 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   648 PDMPPTksvSEPVPFETEAPSMTIVPTTDIEPVTVRTEATVTTLA----PKTSQRTRTRRPRPKHKTTPRPETLQTKldf 723
Cdd:pfam03154  404 THHPPS---AHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAAshppTSGLHQVPSQSPFPQHPFVPGGPPPITP--- 477

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   724 gPITPGTSSAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVPATILEPVLrtEASGTTAAPKVPQRTHRPHP 793
Cdd:pfam03154  478 -PSGPPTSTSSAMPGIQPPSSASVSSSGPVPAAVSCPLPPVQIKEEAL--DEAEEPESPPPPPRSPSPEP 544
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 732-1229 4.03e-16

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 84.99  E-value: 4.03e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  732 SAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVP-ATILEPV-------------LRTEASG-------TTAAPKVPQR--- 787
Cdd:PHA03247 2490 FAAGAAPDPGGGGPPDPDAPPAPSRLAPAILPdEPVGEPVhprmltwirgleeLASDDAGdpppplpPAAPPAAPDRsvp 2569

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  788 THRPHPKPKTTLSPEELQTELVP---ATIFEPVSPIKEAPGTTfvPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPK 864
Cdd:PHA03247 2570 PPRPAPRPSEPAVTSRARRPDAPpqsARPRAPVDDRGDPRGPA--PPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVP 2647

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  865 TtpsPQAPETKPVPATVLEPVTLRPEASTTLASKTSQRTRRPRLRTKTTP-----RPEAPESKPVPtaelkpvtlRTETW 939
Cdd:PHA03247 2648 P---PERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSltslaDPPPPPPTPEP---------APHAL 2715

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  940 VT-TQAPKTSQRTRRPRPKTKTTPSPevpqtklvPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTR 1018
Cdd:PHA03247 2716 VSaTPLPPGPAAARQASPALPAAPAP--------PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPA 2787

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1019 RPRPRPKTTS--SPEVPQNKSVSVTGFEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESqPVSDVLESVTLSTES 1096
Cdd:PHA03247 2788 VASLSESRESlpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP-LGGSVAPGGDVRRRP 2866

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1097 PKETIAPAKTDYVYPTAKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPK 1176
Cdd:PHA03247 2867 PSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767926294 1177 TSPRPRIPQTQPVPK------VPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVS 1229
Cdd:PHA03247 2947 TDPAGAGEPSGAVPQpwlgalVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVS 3005
PHA03247 PHA03247
large tegument protein UL36; Provisional
 589-979 2.96e-14

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 78.83  E-value: 2.96e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  589 PKSKPALEPATiqPEPLVPTT--ASKPSERPKTT--HRPDAPQIQ--------PGSKPPKQLLPKPQTTAEPDMPPTKSV 656
Cdd:PHA03247 2553 PPLPPAAPPAA--PDRSVPPPrpAPRPSEPAVTSraRRPDAPPQSarprapvdDRGDPRGPAPPSPLPPDTHAPDPPPPS 2630

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  657 SEPVPFETEAPSMTIVPttdiEPVTVRTEATVTTLA-PKTSQRTRTRRPRPKHKTTPRPETLQTkldfgPITPGTSSA-- 733
Cdd:PHA03247 2631 PSPAANEPDPHPPPTVP----PPERPRDDPAPGRVSrPRRARRLGRAAQASSPPQRPRRRAARP-----TVGSLTSLAdp 2701

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  734 PTTTTKRTRRPHPKPKTTPHPEVPQT--KLVPATILEPVLRTEASGTT--------AAPKVPQRTHRPHPK--PKTTLSP 801
Cdd:PHA03247 2702 PPPPPTPEPAPHALVSATPLPPGPAAarQASPALPAAPAPPAVPAGPAtpggparpARPPTTAGPPAPAPPaaPAAGPPR 2781

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  802 EELQTELVPATIFEPVSPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAPETKPVPATv 881
Cdd:PHA03247 2782 RLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGG- 2860

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  882 lePVTLRPEASTTlASKTSQRTRRPRLRTKTTPRPEAPESKPVPTAELKPVTlrtetwvTTQAPKTSQRTRRPRPKTKTT 961
Cdd:PHA03247 2861 --DVRRRPPSRSP-AAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPP-------QPQAPPPPQPQPQPPPPPQPQ 2930

                         410       420
                  ....*....|....*....|.
gi 767926294  962 PSPEV---PQTKLVPSTDLEP 979
Cdd:PHA03247 2931 PPPPPpprPQPPLAPTTDPAG 2951
PHA03247 PHA03247
large tegument protein UL36; Provisional
 432-934 1.30e-12

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 73.43  E-value: 1.30e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  432 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE--RTTSAGTITPKISKSPEPTWTT 509
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGdpRGPAPPSPLPPDTHAPDPPPPS 2630

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  510 PAPGKTQfiSLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVP 589
Cdd:PHA03247 2631 PSPAANE--PDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTP 2708

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  590 KSKPalePATIQPEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPP--KQLLPKPQTTAEPD--MPPTKSVSEPVPFETE 665
Cdd:PHA03247 2709 EPAP---HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPggPARPARPPTTAGPPapAPPAAPAAGPPRRLTR 2785

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  666 APSMTIVPTTDIEP-----------VTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDfGPITPGtssAP 734
Cdd:PHA03247 2786 PAVASLSESRESLPspwdpadppaaVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG-GSVAPG---GD 2861

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  735 TTTTKRTRRPHPKPKTTPHPEV-----PQTKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEE------ 803
Cdd:PHA03247 2862 VRRRPPSRSPAAKPAAPARPPVrrlarPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPpprpqp 2941

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  804 -LQTELVPATIFEPvSPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATKTSKRTRPPRPRPKTTPSPQAP-----ETKPV 877
Cdd:PHA03247 2942 pLAPTTDPAGAGEP-SGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSlalheETDPP 3020

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767926294  878 PATVLEpvTLRPEASTTLASKTSQRTRRPRLRTKTTPRPEAPESKPVPTAELKPVTL 934
Cdd:PHA03247 3021 PVSLKQ--TLWPPDDTEDSDADSLFDSDSERSDLEALDPLPPEPHDPFAHEPDPATP 3075
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 1511-1602 1.16e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 56.74  E-value: 1.16e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1511 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 1588
Cdd:cd00063     2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                          90
                  ....*....|....
gi 767926294 1589 LGEGPVSNTVAFST 1602
Cdd:cd00063    80 GGESPPSESVTVTT 93
PHA03247 PHA03247
large tegument protein UL36; Provisional
 422-754 9.15e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 60.72  E-value: 9.15e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  422 PPKTSRTLE-QPRATLAPSETPFVPQKL-EIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPki 499
Cdd:PHA03247 2701 PPPPPPTPEpAPHALVSATPLPPGPAAArQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAG-- 2778

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  500 skspePTWTTPAPGKTQFISLKPKIPLSPEvthtkPAPEPQTLLPSQSTigpETPGTKPSTTLAPRKTKRPGRRPRPRPR 579
Cdd:PHA03247 2779 -----PPRRLTRPAVASLSESRESLPSPWD-----PADPPAAVLAPAAA---LPPAASPAGPLPPPTSAQPTAPPPPPGP 2845

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  580 PKTTPSPE--VPKSKPALEPATIQPEPLVPTTASKPSER-------PKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEPDM 650
Cdd:PHA03247 2846 PPPSLPLGgsVAPGGDVRRRPPSRSPAAKPAAPARPPVRrlarpavSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPP 2925

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  651 PPTKSVSEPVPFETEAPsmtIVPTTDIEPVtvrteatvttlapktsqrtrtrrprpkhkttPRPETLQTKLDFGPITPGT 730
Cdd:PHA03247 2926 PPQPQPPPPPPPRPQPP---LAPTTDPAGA-------------------------------GEPSGAVPQPWLGALVPGR 2971

                         330       340
                  ....*....|....*....|....
gi 767926294  731 SSAPTTTTKRTRRPHPKPKTTPHP 754
Cdd:PHA03247 2972 VAVPRFRVPQPAPSREAPASSTPP 2995
PHA03247 PHA03247
large tegument protein UL36; Provisional
 422-797 1.46e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 60.34  E-value: 1.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  422 PPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPK--- 498
Cdd:PHA03247 2608 PRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRrra 2687

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  499 ---------ISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPePQTLLPSQSTIGPETPGT-----KPSTTLAP 564
Cdd:PHA03247 2688 arptvgsltSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPAL-PAAPAPPAVPAGPATPGGparpaRPPTTAGP 2766

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  565 rkTKRPGRRPRPRPRPKTTPSPEVPKSKPALEPATIQPEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPPKQLLPKPQT 644
Cdd:PHA03247 2767 --PAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG 2844

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  645 TAEPDMPPTKSVSEPVPFETEAPSMTIVPTtdiepVTVRTEATVTTLA-PKTSQRTRTRRPRPKHKTTPR-PETLQTKLD 722
Cdd:PHA03247 2845 PPPPSLPLGGSVAPGGDVRRRPPSRSPAAK-----PAAPARPPVRRLArPAVSRSTESFALPPDQPERPPqPQAPPPPQP 2919

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767926294  723 FGPITPGTSSAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVPAtilePVLRTEASGTTAAPK--VPQ-RTHRPHPKPKT 797
Cdd:PHA03247 2920 QPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQ----PWLGALVPGRVAVPRfrVPQpAPSREAPASST 2993
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 1512-1592 1.59e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 50.31  E-value: 1.59e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   1512 PPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV-ISRENGSFSGKNKSIQMTNQTFS-TVENLKPNTSYEFQVKPKNPL 1589
Cdd:smart00060    3 PPSNLRVTDVT--STSVTLSWEPPPDDGITGYIVgYRVEYREEGSEWKEVNVTPSSTSyTLTGLKPGTEYEFRVRAVNGA 80


                    ...
gi 767926294   1590 GEG 1592
Cdd:smart00060   81 GEG 83
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 655-1254 2.99e-06

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 52.39  E-value: 2.99e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  655 SVSEPVPFETEAPSMTIVPTTDIEPVTvrTEATVTTLAPKTSQRTRtrrprpKHKTTPRPETLQTKLDFGPitpgTSSAP 734
Cdd:PRK10263  315 PITEPVAVAAAATTATQSWAAPVEPVT--QTPPVASVDVPPAQPTV------AWQPVPGPQTGEPVIAPAP----EGYPQ 382

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  735 TTTTKRTRRPHPKPKTTPHPEVPQTKLVPATILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVPATIF 814
Cdd:PRK10263  383 QSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTY 462

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  815 EPVSPIKE--APGTTFVPVTDLEPVTFRTEIPATTlATKTSKRTRPPRPRPKTTPSPQ----APETKPVPATVLEPVTLR 888
Cdd:PRK10263  463 QTEQTYQQpaAQEPLYQQPQPVEQQPVVEPEPVVE-ETKPARPPLYYFEEVEEKRAREreqlAAWYQPIPEPVKEPEPIK 541

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  889 PEASTTLASKTSqrtrrprlrtkttPRPEAPESKPVpTAELKPVTLRTETWVTTQAPKTSQRTR-RPRPKTKTTPSPEVP 967
Cdd:PRK10263  542 SSLKAPSVAAVP-------------PVEAAAAVSPL-ASGVKKATLATGAAATVAAPVFSLANSgGPRPQVKEGIGPQLP 607

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  968 QtklvpstdlepgtlrteaPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPKTTS----------SPEVPQNKS 1037
Cdd:PRK10263  608 R------------------PKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQynddeidamqQDELARQFA 669

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1038 VSVTGFEPVVHSTDAPGTT--------------FALTELQTLILKPVTSP---SLEMTESQPVSDVLEsvtlstESPKEt 1100
Cdd:PRK10263  670 QTQQQRYGEQYQHDVPVNAedadaaaeaelarqFAQTQQQRYSGEQPAGAnpfSLDDFEFSPMKALLD------DGPHE- 742

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1101 iaPAKTDYVYPTAKaPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQsitlPSPDEPQTEPAPKQTPRAPPKPkTSPR 1180
Cdd:PRK10263  743 --PLFTPIVEPVQQ-PQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQ----PQYQQPQQPVAPQPQYQQPQQP-VAPQ 814

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767926294 1181 PRIPQTQPvPKVPQRVTAKPKTSPSpevsyttPAPKDVLLpHKPYPEVSQSEPVLQPVT-----FRFEPPKTTIAPLET 1254
Cdd:PRK10263  815 PQYQQPQQ-PVAPQPQYQQPQQPVA-------PQPQDTLL-HPLLMRNGDSRPLHKPTTplpslDLLTPPPSEVEPVDT 884
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 1112-1364 1.04e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 50.85  E-value: 1.04e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1112 TAKAPLW--PEEPKTEVVESITYVSEPPETTLETSPLPSqsitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPV 1189
Cdd:PRK10263  327 TTATQSWaaPVEPVTQTPPVASVDVPPAQPTVAWQPVPG-----PQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPV 401

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1190 PkvPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPVLQPVTfrfEPPKTTIAPLETRGiPFIPMISPSPsq 1269
Cdd:PRK10263  402 Q--PQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA---EEQQSTFAPQSTYQ-TEQTYQQPAA-- 473

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1270 eelQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSD---------KPHIRPVLNRTTTRPTRPKPS-- 1338
Cdd:PRK10263  474 ---QEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRARereqlaawyQPIPEPVKEPEPIKSSLKAPSva 550

                         250       260       270
                  ....*....|....*....|....*....|..
gi 767926294 1339 ------GMPSGNGVGTGVKQAPRPSGADRNVS 1364
Cdd:PRK10263  551 avppveAAAAVSPLASGVKKATLATGAAATVA 582
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 1069-1338 1.83e-05

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 49.69  E-value: 1.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1069 PVTSPSLEMTESQPVSDVLESvtlstESPKETIAPAKTDYVYPTAKaplwPEEPKTEVVESITYVSEPPEttletspLPS 1148
Cdd:PTZ00449  520 PPKAPGDKEGEEGEHEDSKES-----DEPKEGGKPGETKEGEVGKK----PGPAKEHKPSKIPTLSKKPE-------FPK 583

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1149 QSitlPSPDEPQtEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTA--KPKTSPSPEVSYTTPAPKDVLLPHKPYP 1226
Cdd:PTZ00449  584 DP---KHPKDPE-EPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESpkSPKRPPPPQRPSSPERPEGPKIIKSPKP 659

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1227 EVSQSEPvlqpvtfrFEPPKTTiapletrgiPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPhr 1306
Cdd:PTZ00449  660 PKSPKPP--------FDPKFKE---------KFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRP-- 720

                         250       260       270
                  ....*....|....*....|....*....|..
gi 767926294 1307 fYTTVRPRTSDKPHIRPvlnrttTRPTRPKPS 1338
Cdd:PTZ00449  721 -LPPKLPRDEEFPFEPI------GDPDAEQPD 745
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1115-1476 2.01e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.94  E-value: 2.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1115 APLWPEEPKTEVVESityvsEPPETTLETSPLPSQSitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVP---K 1191
Cdd:PHA03247 2591 APPQSARPRAPVDDR-----GDPRGPAPPSPLPPDT---HAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPgrvS 2662

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1192 VPQRVTAK--PKTSPSPEVSYTTPAPKDVLLP---------------HKPYPEVSQSEPVLQPVTFRFEPPKTTIAPLeT 1254
Cdd:PHA03247 2663 RPRRARRLgrAAQASSPPQRPRRRAARPTVGSltsladpppppptpePAPHALVSATPLPPGPAAARQASPALPAAPA-P 2741

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1255 RGIPFIPMISPSPSQEELQTTLEETDQST--QEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPVLNRTTTRP 1332
Cdd:PHA03247 2742 PAVPAGPATPGGPARPARPPTTAGPPAPAppAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1333 TRPKPSGMPSGNGVGTGVKQAPRPSGADRNV--SVDSTHPTKKPGTRRPplppRPTHPRRKPLPPNNVTGKPGSAGIISS 1410
Cdd:PHA03247 2822 ASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLggSVAPGGDVRRRPPSRS----PAAKPAAPARPPVRRLARPAVSRSTES 2897

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767926294 1411 GPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVR 1476
Cdd:PHA03247 2898 FALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPW 2963
fn3 pfam00041
Fibronectin type III domain;
1512-1595 4.59e-05

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 43.56  E-value: 4.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  1512 PPTNLTVVTVEgcPSFVILDWEKP--LNDTVTEYEVISRENGSFSGKNkSIQMTNQTFS-TVENLKPNTSYEFQVKPKNP 1588
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPpdGNGPITGYEVEYRPKNSGEPWN-EITVPGTTTSvTLTGLKPGTEYEVRVQAVNG 78


                   ....*..
gi 767926294  1589 LGEGPVS 1595
Cdd:pfam00041   79 GGEGPPS 85
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 946-1342 6.09e-05

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 48.15  E-value: 6.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  946 KTSQRTRRPRPKTKTTPSPEVPQTKLVPSTDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPK 1025
Cdd:PTZ00449  528 EGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRSAQRPT 607

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1026 TTSSPEVPQNKSVSVTGFEPvvHSTDAPgttfaltelqtlilKPVTSPSLEMTESQPVSDVLESVTLSTESPKETIAPAK 1105
Cdd:PTZ00449  608 RPKSPKLPELLDIPKSPKRP--ESPKSP--------------KRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKF 671

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1106 TDYVYPT-AKAPLWPEEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPKTSP----- 1179
Cdd:PTZ00449  672 KEKFYDDyLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGDPDAEQPDDiefft 751

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1180 -----RPRIPQTQPVPKVPQRVTAKPKTspsPEVSYTTPAPKDVL----LPHKPYPEVSQSEPVLQPVTFRFEPPKTTIA 1250
Cdd:PTZ00449  752 ppeeeRTFFHETPADTPLPDILAEEFKE---EDIHAETGEPDEAMkrpdSPSEHEDKPPGDHPSLPKKRHRLDGLALSTT 828

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1251 PLETRgiPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELA-----------KTTQAPHRFYTTVRPRTSDKP 1319
Cdd:PTZ00449  829 DLESD--AGRIAKDASGKIVKLKRSKSFDDLTTVEEAEEMGAEARKIVvdddgteaddeDTHPPEEKHKSEVRRRRPPKK 906

                         410       420
                  ....*....|....*....|...
gi 767926294 1320 HIRPVLNRTTTRPTRPKPSGMPS 1342
Cdd:PTZ00449  907 PSKPKKPSKPKKPKKPDSAFIPS 929
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 1138-1232 8.37e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 47.50  E-value: 8.37e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1138 ETTLETSPLPSQ-SITLPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPK 1216
Cdd:PRK14950  357 EALLVPVPAPQPaKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAPKLTRAAI 436

                          90
                  ....*....|....*.
gi 767926294 1217 DVLLPHKPYPEVSQSE 1232
Cdd:PRK14950  437 PVDEKPKYTPPAPPKE 452
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1092-1426 4.78e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.16  E-value: 4.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1092 LSTESPKETIAPAKTDYVYPTAKAPLWPE-EPKTEVV--ESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQT 1168
Cdd:PHA03307   44 VSDSAELAAVTVVAGAAACDRFEPPTGPPpGPGTEAPanESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPP 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1169 PRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPVLQPVTFRFEPPKTT 1248
Cdd:PHA03307  124 ASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAAS 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1249 IAPLETRGIPFIPMISPSPS---QEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVR------PRTSDKP 1319
Cdd:PHA03307  204 PRPPRRSSPISASASSPAPApgrSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWeasgwnGPSSRPG 283

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1320 HIRPvlnRTTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVT 1399
Cdd:PHA03307  284 PASS---SSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPA 360

                         330       340
                  ....*....|....*....|....*..
gi 767926294 1400 GKPGSAGIISSGPITTPPLRSTPRPTG 1426
Cdd:PHA03307  361 DPSSPRKRPRPSRAPSSPAASAGRPTR 387
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1328-1607 5.30e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 44.61  E-value: 5.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1328 TTTRPTRPKPSGMPSGNGVGTGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGI 1407
Cdd:COG3401    48 TKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGTATT 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1408 ISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYIQKPDNS--- 1484
Cdd:COG3401   128 ATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTyyy 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1485 -PCSITDSVKRFPKEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEvISRENGSfSGKNKSIQMT 1563
Cdd:COG3401   208 rVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTESDATGYR-VYRSNSG-DGPFTKVATV 282

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 767926294 1564 NQTFSTVENLKPNTSYEFQVKPKNPLG-EGPVSNTVAFSTESADP 1607
Cdd:COG3401   283 TTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 1039-1292 5.97e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 45.08  E-value: 5.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1039 SVTgfEPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESQPVSDVLESVTLSTESPkeTIAPAKTDYV-YPTAKAPL 1117
Cdd:PRK10263  315 PIT--EPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEP--VIAPAPEGYPqQSQYAQPA 390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1118 WP-----EEPKTEVVESITYVSEPPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPK-----PKTSPRPRIPQTQ 1187
Cdd:PRK10263  391 VQyneplQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQqstfaPQSTYQTEQTYQQ 470

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1188 PVPK-----VPQRVTAKPKTSPSPEVSYTTPAPKDVL----LPHKPYPEVSQSEPVLQPVTFRFEPPKTTIAPLETRGIP 1258
Cdd:PRK10263  471 PAAQeplyqQPQPVEQQPVVEPEPVVEETKPARPPLYyfeeVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVA 550

                         250       260       270
                  ....*....|....*....|....*....|....
gi 767926294 1259 FIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP 1292
Cdd:PRK10263  551 AVPPVEAAAAVSPLASGVKKATLATGAAATVAAP 584
fn3 pfam00041
Fibronectin type III domain;
123-202 6.13e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 40.48  E-value: 6.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   123 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPND-RFYTIRYREKDKEKKWIFQICPATET--IVENLKPNTVYEF 199
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71


                   ...
gi 767926294   200 GVK 202
Cdd:pfam00041   72 RVQ 74
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 124-202 6.30e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 40.29  E-value: 6.30e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294    124 PLQLVVGTLTPSSVFLSWgflinphhdwtLPSHCPNDRFYTIRYREKDKEKKWIFQICPA----TETIVENLKPNTVYEF 199
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSW-----------EPPPDDGITGYIVGYRVEYREEGSEWKEVNVtpssTSYTLTGLKPGTEYEF 72


                    ...
gi 767926294    200 GVK 202
Cdd:smart00060   73 RVR 75
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
1506-1650 6.78e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 44.61  E-value: 6.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1506 TSPPQnPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV--ISRENGSFSGKNKSIqmtNQTFSTVENLKPNTSYEFQV 1583
Cdd:COG3401   324 LTPPA-APSGLTATAVG--SSSITLSWTASSDADVTGYNVyrSTSGGGTYTKIAETV---TTTSYTDTGLTPGTTYYYKV 397

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767926294 1584 KPKNPLG-EGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVG 1650
Cdd:COG3401   398 TAVDAAGnESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTG 465
PRK11633 PRK11633
cell division protein DedD; Provisional
 1113-1216 7.96e-04

cell division protein DedD; Provisional


Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 43.07  E-value: 7.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1113 AKAPLWP---EEPKTEVVESITYV--SEPPETTLE-----TSPLPSQSITLPSPDEPQTEPAPKqtPRAPPKPKtsPRPR 1182
Cdd:PRK11633   39 AAIPLVPkpgDRDEPDMMPAATQAlpTQPPEGAAEavragDAAAPSLDPATVAPPNTPVEPEPA--PVEPPKPK--PVEK 114

                          90       100       110
                  ....*....|....*....|....*....|....
gi 767926294 1183 iPQTQPVPKVPQRVTAKPKTSPSPEVSyTTPAPK 1216
Cdd:PRK11633  115 -PKPKPKPQQKVEAPPAPKPEPKPVVE-EKAAPT 146
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 593-661 1.31e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 43.64  E-value: 1.31e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767926294  593 PALEPATIQPEPLVPTtASKPSERPKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEPDMPPTKSVSEPVP 661
Cdd:PRK14950  362 PVPAPQPAKPTAAAPS-PVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAP 429
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 611-982 1.50e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 43.52  E-value: 1.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  611 SKPSERPKTTHRPDAPQIQPGSKPPKqllpkPQTTAEPDMPPTKSVSEPVPFETEAPSMTIVPTTDIEPVTvrTEATVTT 690
Cdd:PTZ00449  537 SKESDEPKEGGKPGETKEGEVGKKPG-----PAKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRS--AQRPTRP 609

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  691 LAPKTSQRTRTRRPRPKHKTTPRPETlqtkldfgPITPGTSSAPTTTTKRTRRPHPKPKTTPHPEV-PQTK-LVPATILE 768
Cdd:PTZ00449  610 KSPKLPELLDIPKSPKRPESPKSPKR--------PPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFdPKFKeKFYDDYLD 681

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  769 PVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVP------ATIFEPV-SPIKEAPGTTFVPVTDLEPVTFRT 841
Cdd:PTZ00449  682 AAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPklprdeEFPFEPIgDPDAEQPDDIEFFTPPEEERTFFH 761

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  842 EIPATTLATKTSKRTRPPRPRPKTTPSPQAPETKPvpatvLEPVTLRPEASTTLASKTSQRTRRPRLRTKTTPRpEAPES 921
Cdd:PTZ00449  762 ETPADTPLPDILAEEFKEEDIHAETGEPDEAMKRP-----DSPSEHEDKPPGDHPSLPKKRHRLDGLALSTTDL-ESDAG 835

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  922 KPVPTAELKPVTLR-----------------------------------TETWVTTQAPKTSQRTRRPRPKTKTTPSPEV 966
Cdd:PTZ00449  836 RIAKDASGKIVKLKrsksfddlttveeaeemgaearkivvdddgteaddEDTHPPEEKHKSEVRRRRPPKKPSKPKKPSK 915

                         410
                  ....*....|....*.
gi 767926294  967 PQTKLVPSTDLEPGTL 982
Cdd:PTZ00449  916 PKKPKKPDSAFIPSII 931
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 889-1215 2.07e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 42.64  E-value: 2.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   889 PEASTTLASKTSQRT-RRPRLRTKTTPRPEAPESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPSPEVP 967
Cdd:pfam17823   66 APAPVTLTKGTSAAHlNSTEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSEAFSAP 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   968 QTKlVPSTdlePGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAPKTQRTRRPRPRPKTTS----SPEVPQNKSVSVTGF 1043
Cdd:pfam17823  146 RAA-ACRA---NASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSApatlTPARGISTAATATGH 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  1044 EPVVHSTDAPGTTFALTELQTLILKPVTSPSLEMTESQPVSDVLESVTLSTESP-KETIAPAKTDYVYPTAKAPLWPEEP 1122
Cdd:pfam17823  222 PAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPhARRLSPAKHMPSDTMARNPAAPMGA 301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  1123 KTEVVESITYVSEPPETTlETSPLPSQSITLPSPDEPQ-----------TEPAPKQTPRAPPKP--KTSPRPRI----PQ 1185
Cdd:pfam17823  302 QAQGPIIQVSTDQPVHNT-AGEPTPSPSNTTLEPNTPKsvastnlavvtTTKAQAKEPSASPVPvlHTSMIPEVeatsPT 380

                          330       340       350
                   ....*....|....*....|....*....|
gi 767926294  1186 TQPVPKVPQRVTAKPKTSPSPEVSYTTPAP 1215
Cdd:pfam17823  381 TQPSPLLPTQGAAGPGILLAPEQVATEATA 410
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 875-1192 2.24e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 42.75  E-value: 2.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  875 KPVPATVLEP-----VTLRPEASTTLAS----KTSQRTRRPRLRTKTT--PRPEAPESKPVPTAELKPvtlrtETWVTTQ 943
Cdd:PTZ00449  560 KPGPAKEHKPskiptLSKKPEFPKDPKHpkdpEEPKKPKRPRSAQRPTrpKSPKLPELLDIPKSPKRP-----ESPKSPK 634

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  944 APKTSQRTRRPR----PKT-KTTPSPEVPQTKLVPS------TDLEPGTLRTEAPKTMVVTTVLEPDTFRTKFPETTLAP 1012
Cdd:PTZ00449  635 RPPPPQRPSSPErpegPKIiKSPKPPKSPKPPFDPKfkekfyDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTP 714

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1013 KTQRTRRPRPRPKTTSSPEVPQNksvsvtgfEPVVHSTDaPGTTFALTELQTLILKpvtspslEMTESQPVSDVL----- 1087
Cdd:PTZ00449  715 FTTPRPLPPKLPRDEEFPFEPIG--------DPDAEQPD-DIEFFTPPEEERTFFH-------ETPADTPLPDILaeefk 778

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1088 -ESVTLSTESPKETIAPAKTDYVYPTAKAPLWPEEPK-----------------------------------TEVVESIT 1131
Cdd:PTZ00449  779 eEDIHAETGEPDEAMKRPDSPSEHEDKPPGDHPSLPKkrhrldglalsttdlesdagriakdasgkivklkrSKSFDDLT 858

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767926294 1132 YVSEPPETTLETSPLPSQSITLPSPDEpQTEPA------------PKQTPRAPPKPKTSPRPRIPQTQPVPKV 1192
Cdd:PTZ00449  859 TVEEAEEMGAEARKIVVDDDGTEADDE-DTHPPeekhksevrrrrPPKKPSKPKKPSKPKKPKKPDSAFIPSI 930
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
844-1012 2.24e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.94  E-value: 2.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  844 PATTLATKTSKRTRPPRPRPKTTPSPQAPETKPVPATVLEPVTLRPEA-----STTLASKTSQRTRRPRLRTKTTPRPEA 918
Cdd:PRK12323  374 PATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAaparrSPAPEALAAARQASARGPGGAPAPAPA 453

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  919 PESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPS-PEVPQTKLVPS-TDLEPGTLRTEAPKTMVVTTVL 996
Cdd:PRK12323  454 PAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPwEELPPEFASPApAQPDAAPAGWVAESIPDPATAD 533

                         170
                  ....*....|....*.
gi 767926294  997 EPDTFRTKFPETTLAP 1012
Cdd:PRK12323  534 PDDAFETLAPAPAAAP 549
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 123-202 3.01e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.63  E-value: 3.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  123 KPLQLVVGTLTPSSVFLSWgfliNPHHDWTLPSHcpndrFYTIRYREKDKE--KKWIFQICPATETIVENLKPNTVYEFG 200
Cdd:cd00063     3 PPTNLRVTDVTSTSVTLSW----TPPEDDGGPIT-----GYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFR 73


                  ..
gi 767926294  201 VK 202
Cdd:cd00063    74 VR 75
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
1136-1213 3.02e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 42.46  E-value: 3.02e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767926294 1136 PPETTLETSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTP 1213
Cdd:PRK14971  391 QPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPVNPPSTAPQAVRPAQFKEEKKIPVSKVSSLGP 468
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
1057-1267 3.20e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.17  E-value: 3.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1057 FALTELQTLILKPVTSPSlemtESQPVSDVLESVTLSTE--SPKETIAPAKTDYVYPTAKAPLwPEEPKTEVVESITYVS 1134
Cdd:PRK12323  353 FTMTLLRMLAFRPGQSGG----GAGPATAAAAPVAQPAPaaAAPAAAAPAPAAPPAAPAAAPA-AAAAARAVAAAPARRS 427

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1135 EPPEttletsplPSQSITLPSPDEPQTEPAPkqTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPA 1214
Cdd:PRK12323  428 PAPE--------ALAAARQASARGPGGAPAP--APAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPP 497

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767926294 1215 PKDVLLPHKPYPEVSQSEPVLQPV---------------TFRFEPPKTTIAPLETRGIPFIPMISPSP 1267
Cdd:PRK12323  498 PWEELPPEFASPAPAQPDAAPAGWvaesipdpatadpddAFETLAPAPAAAPAPRAAAATEPVVAPRP 565
rne PRK10811
ribonuclease E; Reviewed
 1143-1317 5.26e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 41.56  E-value: 5.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1143 TSPLPSQSITLPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQrVTAKPKTSPSPEVSYTTPAPKDVLLPH 1222
Cdd:PRK10811  848 VRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPV-VVAEPQPEEVVVVETTHPEVIAAPVTE 926

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1223 KPYPEVSQSEPVLQPVTFRFEP---------PKTTIAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPR 1293
Cdd:PRK10811  927 QPQVITESDVAVAQEVAEHAEPvvepqdetaDIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQV 1006

                         170       180       190
                  ....*....|....*....|....*....|.
gi 767926294 1294 TTELAKT-------TQAPHRFYTTVRPRTSD 1317
Cdd:PRK10811 1007 PEATVEHnhatapmTRAPAPEYVPEAPRHSD 1037
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
 1157-1237 5.38e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 41.47  E-value: 5.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1157 DEPQTEPAPKQTPRAPPKPKTSPRP-RIPQTQPVPKVPQRVTAKPKTSPSPEVSYT----TPAPKDVLLPHKPYPEVSQS 1231
Cdd:PRK14954  374 VRNDGGVAPSPAGSPDVKKKAPEPDlPQPDRHPGPAKPEAPGARPAELPSPASAPTpeqqPPVARSAPLPPSPQASAPRN 453


                  ....*.
gi 767926294 1232 EPVLQP 1237
Cdd:PRK14954  454 VASGKP 459
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 519-963 5.75e-03

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 41.68  E-value: 5.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   519 SLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRKTKRPGRRPRPRPRPKTTPSPEVPKSKPALEP- 597
Cdd:pfam03154  143 STSPSIPSPQDNESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTq 222

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   598 ATIQPEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEPDMPPTksvsePVPFETEAPSMtivpttdi 677
Cdd:pfam03154  223 STAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSLHGQMPPM-----PHSLQTGPSHM-------- 289

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   678 ePVTVRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETlqtkldfgpiTPGTSSAPTTTTKRTRRPHPKPKTTPHPEVP 757
Cdd:pfam03154  290 -QHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHT----------PPSQSQLQSQQPPREQPLPPAPLSMPHIKPP 358

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   758 QtklvpatilepvlrteasgTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVPATIFEPVSPIK-EAPGTTFVPVTDLEP 836
Cdd:pfam03154  359 P-------------------TTPIPQLPNPQSHKHPPHLSGPSPFQMNSNLPPPPALKPLSSLStHHPPSAHPPPLQLMP 419

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   837 VTFRTEIPATT--LATKTSKRTRPPRPRPKTTPSPQAPETKPVPATVLEPVTlRPEASTTLASKTSQRTRRPRLRTKTTP 914
Cdd:pfam03154  420 QSQQLPPPPAQppVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGG-PPPITPPSGPPTSTSSAMPGIQPPSSA 498

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 767926294   915 RPEAPESKP-VPTAELKPVTLRTETWVTTQAPKT---SQRTRRPRPKTKTTPS 963
Cdd:pfam03154  499 SVSSSGPVPaAVSCPLPPVQIKEEALDEAEEPESpppPPRSPSPEPTVVNTPS 551
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
522-748 7.30e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.01  E-value: 7.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  522 PKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAPRktkrpgrrprprprpKTTPSPEVPKSKPALEPATIQ 601
Cdd:PRK12323  374 PATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAAR---------------AVAAAPARRSPAPEALAAARQ 438

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  602 PEPLVPTTASKPSERPKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEPDMPPTKSVSEPVPFETEAPSMTIVPTTDIEPVT 681
Cdd:PRK12323  439 ASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAP 518

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767926294  682 VRTEAtvttlapktsqrtrtrrprpkhKTTPRPETLQTKLDFGPITPGTSSAPTTTTKRTRRPHPKP 748
Cdd:PRK12323  519 AGWVA----------------------ESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAP 563
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 536-975 7.42e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.06  E-value: 7.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   536 APEPQTLLPSQSTIGPETPGTK---PSTTLAPRKTKRPGRRPRPRPRPKTTpSPEVPKSKPALEPATIQPEPLVPTTASK 612
Cdd:pfam05109  424 APESTTTSPTLNTTGFAAPNTTtglPSSTHVPTNLTAPASTGPTVSTADVT-SPTPAGTTSGASPVTPSPSPRDNGTESK 502

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   613 PSERPKTTHRPDAPQIQPGSKPPKQLLPKPQTTAEP--DMPPTKSVSEPVPFETEAPSMTIVPTTDiepvtvrteATVTT 690
Cdd:pfam05109  503 APDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTlgKTSPTSAVTTPTPNATSPTPAVTTPTPN---------ATIPT 573

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   691 LApKTSqrtrtrrprpkhkttprpetlqtkldfgPITPGTSSAPTTTTKRTRRPHPKPKTTPHPevpqtklVPATILEPV 770
Cdd:pfam05109  574 LG-KTS----------------------------PTSAVTTPTPNATSPTVGETSPQANTTNHT-------LGGTSSTPV 617

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   771 LRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEELQTELVPATIFEPVSpikEAPGTTFVPVTDLEPVTFRTEIPATTLAT 850
Cdd:pfam05109  618 VTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTS---HMPLLTSAHPTGGENITQVTPASTSTHHV 694

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   851 KTSkRTRPPRPRPKTTPSPQAPETKPVPATVLEPVTLRPEASTTLASKTSQRTRRPRLRTK------------TTPRPEA 918
Cdd:pfam05109  695 STS-SPAPRPGTTSQASGPGNSSTSTKPGEVNVTKGTPPKNATSPQAPSGQKTAVPTVTSTggkansttggkhTTGHGAR 773

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 767926294   919 PESKPVPTAELKPVTLRTETWVTTQAPKTSQRTRRPRPKTKTTPSPEVPQTKLVPST 975
Cdd:pfam05109  774 TSTEPTTDYGGDSTTPRTRYNATTYLPPSTSSKLRPRWTFTSPPVTTAQATVPVPPT 830
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 408-793 8.27e-03

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 40.91  E-value: 8.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   408 QPQTATSDRILDSIPPKTSRTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE 487
Cdd:pfam03154  170 QPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   488 RTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPEPQTLLPSQSTIGPETPGTKPSTTLAprKT 567
Cdd:pfam03154  250 QPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRI--HT 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   568 KRPGRRPRPRPRPKTTPSPEVPKSKPALEPATIQPEPLVPTTASKpsERPKTTHRPDAPQIQPGSKPPKQLlpKPQTTAE 647
Cdd:pfam03154  328 PPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSH--KHPPHLSGPSPFQMNSNLPPPPAL--KPLSSLS 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   648 PDMPPTksvSEPVPFETEAPSMTIVPTTDIEPVTVRTEATVTTLA----PKTSQRTRTRRPRPKHKTTPRPETLQTKldf 723
Cdd:pfam03154  404 THHPPS---AHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAAshppTSGLHQVPSQSPFPQHPFVPGGPPPITP--- 477

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294   724 gPITPGTSSAPTTTTKRTRRPHPKPKTTPHPEVPQTKLVPATILEPVLrtEASGTTAAPKVPQRTHRPHP 793
Cdd:pfam03154  478 -PSGPPTSTSSAMPGIQPPSSASVSSSGPVPAAVSCPLPPVQIKEEAL--DEAEEPESPPPPPRSPSPEP 544
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 646-1218 9.17e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 40.84  E-value: 9.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  646 AEPDMPptksvSEPVPFETEAPSMtivPTTDIEPVT-VRTEATVTTLAPKTSQRTRTRRPRPKHKTTPRPETLQTKLDFG 724
Cdd:PRK10263  337 VEPVTQ-----TPPVASVDVPPAQ---PTVAWQPVPgPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYY 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  725 PITPGTSSAPTTTTKRTRRPHPKPKTTPHPEVPqtklvpatILEPVLRTEASGTTAAPKVPQRTHRPHPKPKTTLSPEEL 804
Cdd:PRK10263  409 APAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQP--------VAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQ 480

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  805 QTELVPATIFEPVsPIKEAPGTTFVPVTDLEPVTFRTEIPATTLATktskrTRPPRPRPKTTPSPQAPETKPVPATVLEP 884
Cdd:PRK10263  481 PQPVEQQPVVEPE-PVVEETKPARPPLYYFEEVEEKRAREREQLAA-----WYQPIPEPVKEPEPIKSSLKAPSVAAVPP 554

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  885 VTLRPeASTTLASKTSQRTrrprLRTKTTPRPEAPESKPVPTAELKPvtlRTETWVTTQAPKtSQRTRRPRPKTKTTPSP 964
Cdd:PRK10263  555 VEAAA-AVSPLASGVKKAT----LATGAAATVAAPVFSLANSGGPRP---QVKEGIGPQLPR-PKRIRVPTRRELASYGI 625

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294  965 EVPQTKLVPSTDLEPGTLRTEAPKTMVVTTV--LEPDTFRTKFPETTLAP--KTQRTRRPRPRPKTTSSPEVPQNKSVSV 1040
Cdd:PRK10263  626 KLPSQRAAEEKAREAQRNQYDSGDQYNDDEIdaMQQDELARQFAQTQQQRygEQYQHDVPVNAEDADAAAEAELARQFAQ 705

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1041 TGFEPVVHSTDAPGTTFALTELQtlilkpvTSPSLEMTESQPVSDVLESVTLSTESPKETIAPAktdyvyPTAKAPLWPE 1120
Cdd:PRK10263  706 TQQQRYSGEQPAGANPFSLDDFE-------FSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQ------QQYQQPQQPV 772

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767926294 1121 EPKTEVVESITYVSEPPETTLETSPLPSQsitlPSPDEPQTEPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKP 1200
Cdd:PRK10263  773 APQPQYQQPQQPVAPQPQYQQPQQPVAPQ----PQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTLLHP 848

                         570       580       590
                  ....*....|....*....|....*....|.
gi 767926294 1201 -------------KTSPSPEVSYTTPAPKDV 1218
Cdd:PRK10263  849 llmrngdsrplhkPTTPLPSLDLLTPPPSEV 879
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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