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Conserved domains on  [gi|767908640|ref|XP_011507585|]
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coagulation factor XIII B chain isoform X1 [Homo sapiens]

Protein Classification

CCP domain-containing protein( domain architecture ID 13332024)

CCP domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 230-451 6.06e-25

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 104.73  E-value: 6.06e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 230 TYEEGDVVQFFCHENYYLS--GSDLIQCYNFGWypeSPVCEGRRNRCPPPPLPINSKIQTHSTTYrhGEIVHIECELNFE 307
Cdd:PHA02927  43 NYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGW---TLFNQCIKRRCPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQ 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 308 IHGSAEIRCEDGK-----WT-EPPKCiegqEKVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNRG 381
Cdd:PHA02927 118 LIGESKSYCELGStgsmvWNpEAPIC----ESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGG 193

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767908640 382 KWTLPPECveNNENCKHpPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCEQGKWSSP--PVCL 451
Cdd:PHA02927 194 EWSDPPTC--QIVKCPH-PTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKCV 262
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 91-328 6.64e-14

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 72.38  E-value: 6.64e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640  91 CTKPD------LSNGYISDVKLLYKIQENMRYGCASGYKTTGgKDEEVVQCLSDGWSSQPTCRKEHetCLAP-ELYNGNY 163
Cdd:PHA02927  21 CTIPSrpinmkFKNSVETDANANYNIGDTIEYLCLPGYRKQK-MGPIYAKCTGTGWTLFNQCIKRR--CPSPrDIDNGQL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 164 STTQKTFKvkDKVQYECATGYYTAGGKKT--EEVECLTYGWS-LTPKCTKLKCSSLRLIENGYFHPVKQTYEEGDVVQFF 240
Cdd:PHA02927  98 DIGGVDFG--SSITYSCNSGYQLIGESKSycELGSTGSMVWNpEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYS 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 241 CHENYYLSGSDLIQCYNFGWyPESPVCEgrRNRCPPPPLPINSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCEDGK 320
Cdd:PHA02927 176 CNSGYSLIGNSGVLCSGGEW-SDPPTCQ--IVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGN 252

                        250
                 ....*....|
gi 767908640 321 WTEP--PKCI 328
Cdd:PHA02927 253 TWQPelPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 524-578 4.06e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 50.15  E-value: 4.06e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767908640 524 CTSPPLIKHGVIISSTvDTYENGSSVEYRCFDHHFLEGSREAYCL-DGMWT-TPPLC 578
Cdd:cd00033    1 CPPPPVPENGTVTGSK-GSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTC 56
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 28-126 3.73e-05

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 45.80  E-value: 3.73e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640  28 PHVENGRiaqyYYTFKSFYFPMSIdkkLSFFCLAGYTT--ESGrqeeqTTCTTEGWSPEPRC-FKKCTKPDLSNGYISD- 103
Cdd:PHA02927 152 PSISNGR----HNGYEDFYTDGSV---VTYSCNSGYSLigNSG-----VLCSGGEWSDPPTCqIVKCPHPTISNGYLSSg 219

                         90       100
                 ....*....|....*....|...
gi 767908640 104 VKLLYKIQENMRYGCASGYKTTG 126
Cdd:PHA02927 220 FKRSYSYNDNVDFKCKYGYKLSG 242
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 230-451 6.06e-25

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 104.73  E-value: 6.06e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 230 TYEEGDVVQFFCHENYYLS--GSDLIQCYNFGWypeSPVCEGRRNRCPPPPLPINSKIQTHSTTYrhGEIVHIECELNFE 307
Cdd:PHA02927  43 NYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGW---TLFNQCIKRRCPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQ 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 308 IHGSAEIRCEDGK-----WT-EPPKCiegqEKVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNRG 381
Cdd:PHA02927 118 LIGESKSYCELGStgsmvWNpEAPIC----ESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGG 193

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767908640 382 KWTLPPECveNNENCKHpPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCEQGKWSSP--PVCL 451
Cdd:PHA02927 194 EWSDPPTC--QIVKCPH-PTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 91-328 6.64e-14

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 72.38  E-value: 6.64e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640  91 CTKPD------LSNGYISDVKLLYKIQENMRYGCASGYKTTGgKDEEVVQCLSDGWSSQPTCRKEHetCLAP-ELYNGNY 163
Cdd:PHA02927  21 CTIPSrpinmkFKNSVETDANANYNIGDTIEYLCLPGYRKQK-MGPIYAKCTGTGWTLFNQCIKRR--CPSPrDIDNGQL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 164 STTQKTFKvkDKVQYECATGYYTAGGKKT--EEVECLTYGWS-LTPKCTKLKCSSLRLIENGYFHPVKQTYEEGDVVQFF 240
Cdd:PHA02927  98 DIGGVDFG--SSITYSCNSGYQLIGESKSycELGSTGSMVWNpEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYS 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 241 CHENYYLSGSDLIQCYNFGWyPESPVCEgrRNRCPPPPLPINSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCEDGK 320
Cdd:PHA02927 176 CNSGYSLIGNSGVLCSGGEW-SDPPTCQ--IVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGN 252

                        250
                 ....*....|
gi 767908640 321 WTEP--PKCI 328
Cdd:PHA02927 253 TWQPelPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 274-328 5.39e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 58.24  E-value: 5.39e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767908640 274 CPPPPLPINSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRC-EDGKWT-EPPKCI 328
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 213-267 9.04e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.54  E-value: 9.04e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 767908640   213 CSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPVC 267
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGtWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
213-267 1.93e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.66  E-value: 1.93e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767908640  213 CSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPVC 267
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGtWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 524-578 4.06e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 50.15  E-value: 4.06e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767908640 524 CTSPPLIKHGVIISSTvDTYENGSSVEYRCFDHHFLEGSREAYCL-DGMWT-TPPLC 578
Cdd:cd00033    1 CPPPPVPENGTVTGSK-GSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 524-578 3.79e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 47.52  E-value: 3.79e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 767908640   524 CTSPPLIKHGVIISSTvDTYENGSSVEYRCFDHHFLEGSREAYCL-DGMWT-TPPLC 578
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
524-578 1.43e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.87  E-value: 1.43e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767908640  524 CTSPPLIKHGVIiSSTVDTYENGSSVEYRCFDHHFLEGSREAYCL-DGMWT-TPPLC 578
Cdd:pfam00084   1 CPPPPDIPNGKV-SATKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 28-126 3.73e-05

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 45.80  E-value: 3.73e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640  28 PHVENGRiaqyYYTFKSFYFPMSIdkkLSFFCLAGYTT--ESGrqeeqTTCTTEGWSPEPRC-FKKCTKPDLSNGYISD- 103
Cdd:PHA02927 152 PSISNGR----HNGYEDFYTDGSV---VTYSCNSGYSLigNSG-----VLCSGGEWSDPPTCqIVKCPHPTISNGYLSSg 219

                         90       100
                 ....*....|....*....|...
gi 767908640 104 VKLLYKIQENMRYGCASGYKTTG 126
Cdd:PHA02927 220 FKRSYSYNDNVDFKCKYGYKLSG 242
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 94-147 2.74e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 39.37  E-value: 2.74e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 767908640  94 PDLSNGYISDVKLLYKIQENMRYGCASGYKTTGgkdEEVVQCLSDG-WS-SQPTCR 147
Cdd:cd00033    5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVG---SSTITCTENGgWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 94-146 4.79e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 38.66  E-value: 4.79e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 767908640    94 PDLSNGYISDVKLLYKIQENMRYGCASGYKTTGGkdeEVVQCLSDG-WS-SQPTC 146
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGS---STITCLENGtWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
153-208 5.61e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 38.25  E-value: 5.61e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767908640  153 CLAPE-LYNGNYSTTQKTFKVKDKVQYECATGYYTAGGkktEEVECLTYG-WS-LTPKC 208
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRLVGS---PTITCQEDGtWSpPFPEC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 230-451 6.06e-25

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 104.73  E-value: 6.06e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 230 TYEEGDVVQFFCHENYYLS--GSDLIQCYNFGWypeSPVCEGRRNRCPPPPLPINSKIQTHSTTYrhGEIVHIECELNFE 307
Cdd:PHA02927  43 NYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGW---TLFNQCIKRRCPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQ 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 308 IHGSAEIRCEDGK-----WT-EPPKCiegqEKVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNRG 381
Cdd:PHA02927 118 LIGESKSYCELGStgsmvWNpEAPIC----ESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGG 193

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767908640 382 KWTLPPECveNNENCKHpPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCEQGKWSSP--PVCL 451
Cdd:PHA02927 194 EWSDPPTC--QIVKCPH-PTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 274-517 8.33e-20

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 89.71  E-value: 8.33e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 274 CPPPPLPINSKIQTH-----STTYRHGEIVHIECELNFEIH--GSAEIRCEDGKWTEPPKCIegqeKVACEEPPFIENGA 346
Cdd:PHA02927  21 CTIPSRPINMKFKNSvetdaNANYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGWTLFNQCI----KRRCPSPRDIDNGQ 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 347 ANLHSKIYynGDKVTYACKSGYLLHGSNEITCNRGK-----WTlPPECVENNENCKHPPVVMNGAvADGILASYATGSSV 421
Cdd:PHA02927  97 LDIGGVDF--GSSITYSCNSGYQLIGESKSYCELGStgsmvWN-PEAPICESVKCQSPPSISNGR-HNGYEDFYTDGSVV 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 422 EYRCNEYYLLRGSKISRCEQGKWSSPPVCLepcTVNVDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSpltplSEL 501
Cdd:PHA02927 173 TYSCNSGYSLIGNSGVLCSGGEWSDPPTCQ---IVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLS-----GSS 244

                        250
                 ....*....|....*....
gi 767908640 502 SVQCNRGEV---KYPLCTR 517
Cdd:PHA02927 245 SSTCSPGNTwqpELPKCVR 263
PHA02831 PHA02831
EEV host range protein; Provisional
 229-395 6.31e-15

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 75.41  E-value: 6.31e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 229 QTYEEGDVVQFFCHENYylsGSDLIQCYNFGWYPESpVCEGRRNrCPPPPLPINSKIQTHSTTYRHGEIVHIECELN--- 305
Cdd:PHA02831  38 KVYEENENLEYKCNNNF---DKVFVTCNNGSWSTKN-MCIGKRN-CKDPVTILNGYIKNKKDQYSFGDSVTYACKVNkle 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 306 -FEIHGSAEIRCEDGKWT-EPPKCiegqEKVACEEPPfIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNRGKW 383
Cdd:PHA02831 113 kYSIVGNETVKCINKQWVpKYPVC----KLIRCKYPA-LQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSI 187

                        170
                 ....*....|....
gi 767908640 384 TLP--PECVENNEN 395
Cdd:PHA02831 188 WYPgiPKCVKDKVH 201
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 150-394 8.20e-15

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 75.89  E-value: 8.20e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 150 HETCLAPELYNGNYSTTQKTFKVKDKVQYECATGYYTAGGKKTeeveCLTYGWSLTPKCTKLkCSSLRLIENGYFHPVKQ 229
Cdd:PHA02954  18 YSTCTVPTMNNAKLTSTETSFNDKQKVTFTCDSGYYSLDPNAV----CETDKWKYENPCKKM-CTVSDYVSELYDKPLYE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 230 TYE------EGDVVQFFCHE-NYYLSGSDLIQCYNfgwypespvcegrrNRCPPPPLPINSkIQTHSTTYRHGEIVHIEC 302
Cdd:PHA02954  93 VNStitlicKDETKYFRCEEkNGNTSWNDTVTCPN--------------AECQPLQLEHGS-CQPVKEKYSFGEHITINC 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 303 ELNFEIHGSAEIRCEDGKWTEPPKCiegQEKVaceEPPFIENGAanLHSKIYYNGDKVTYACKSGYLLHGSNEITCNRGK 382
Cdd:PHA02954 158 DVGYEVIGASYISCTANSWNVIPSC---QQKC---DIPSLSNGL--ISGSTFSIGGVIHLSCKSGFTLTGSPSSTCIDGK 229

                        250
                 ....*....|...
gi 767908640 383 WT-LPPECVENNE 394
Cdd:PHA02954 230 WNpVLPICVRSNE 242
PHA02831 PHA02831
EEV host range protein; Provisional
 159-329 6.05e-14

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 72.33  E-value: 6.05e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 159 YNGNYSTTQKTFKVKDKVQYECATGYYTAGgkkteeVECLTYGWSLTPKCT-KLKCSSLRLIENGYFHPVKQTYEEGDVV 237
Cdd:PHA02831  29 YSNVDSYENKVYEENENLEYKCNNNFDKVF------VTCNNGSWSTKNMCIgKRNCKDPVTILNGYIKNKKDQYSFGDSV 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 238 QFFCH----ENYYLSGSDLIQCYNFGWYPESPVCegRRNRCPPPPLPiNSKIQTHSTTYRHGEIVHIECELNFEIHGSAE 313
Cdd:PHA02831 103 TYACKvnklEKYSIVGNETVKCINKQWVPKYPVC--KLIRCKYPALQ-NGFLNVFEKKFYYGDIVNFKCKKGFILLGSSV 179

                        170
                 ....*....|....*...
gi 767908640 314 IRCEDGKWTEP--PKCIE 329
Cdd:PHA02831 180 STCDINSIWYPgiPKCVK 197
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 91-328 6.64e-14

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 72.38  E-value: 6.64e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640  91 CTKPD------LSNGYISDVKLLYKIQENMRYGCASGYKTTGgKDEEVVQCLSDGWSSQPTCRKEHetCLAP-ELYNGNY 163
Cdd:PHA02927  21 CTIPSrpinmkFKNSVETDANANYNIGDTIEYLCLPGYRKQK-MGPIYAKCTGTGWTLFNQCIKRR--CPSPrDIDNGQL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 164 STTQKTFKvkDKVQYECATGYYTAGGKKT--EEVECLTYGWS-LTPKCTKLKCSSLRLIENGYFHPVKQTYEEGDVVQFF 240
Cdd:PHA02927  98 DIGGVDFG--SSITYSCNSGYQLIGESKSycELGSTGSMVWNpEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYS 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 241 CHENYYLSGSDLIQCYNFGWyPESPVCEgrRNRCPPPPLPINSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCEDGK 320
Cdd:PHA02927 176 CNSGYSLIGNSGVLCSGGEW-SDPPTCQ--IVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGN 252

                        250
                 ....*....|
gi 767908640 321 WTEP--PKCI 328
Cdd:PHA02927 253 TWQPelPKCV 262
PHA02639 PHA02639
EEV host range protein; Provisional
 211-392 2.25e-13

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 71.23  E-value: 2.25e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 211 LKCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCY----NFGWYPESPVCEGRrnRCPPPPLPINSKIQ 286
Cdd:PHA02639  20 IYCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIkdknNAIWSNKAPFCMLK--ECNDPPSIINGKIY 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 287 THSTTYRHGEIVHIECE----LNFEIHGSAEIRC-EDGKWT-EPPKCiegqEKVACEEPPfIENGAAN--LHSKIYYNGD 358
Cdd:PHA02639  98 NKREMYKVGDEIYYVCNehkgVQYSLVGNEKITCiQDKSWKpDPPIC----KMINCRFPA-LQNGYINgiPSNKKFYYKT 172

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 767908640 359 KVTYACKSGYLLHGSNEITCNRGKWTLP--PECVEN 392
Cdd:PHA02639 173 RVGFSCKSGFDLVGEKYSTCNINATWFPsiPTCVRN 208
PHA02831 PHA02831
EEV host range protein; Provisional
 108-267 4.01e-13

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 70.02  E-value: 4.01e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 108 YKIQENMRYGCASGYkttggkDEEVVQCLSDGWSSQPTCRKEhETCLAP-ELYNGNYSTTQKTFKVKDKVQYECATG--- 183
Cdd:PHA02831  40 YEENENLEYKCNNNF------DKVFVTCNNGSWSTKNMCIGK-RNCKDPvTILNGYIKNKKDQYSFGDSVTYACKVNkle 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 184 YYTAGGKKTeeVECLTYGW-SLTPKCTKLKCSSLRLiENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQC-YNFGWY 261
Cdd:PHA02831 113 KYSIVGNET--VKCINKQWvPKYPVCKLIRCKYPAL-QNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCdINSIWY 189


                 ....*.
gi 767908640 262 PESPVC 267
Cdd:PHA02831 190 PGIPKC 195
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 88-333 4.08e-13

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 70.89  E-value: 4.08e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640  88 FKKCTKPDLSNGYISDVKLLYKIQENMRYGCASGYKTTggkDEEVVqCLSDGWSSQPTCRKEHETC-LAPELYNgnystt 166
Cdd:PHA02954  18 YSTCTVPTMNNAKLTSTETSFNDKQKVTFTCDSGYYSL---DPNAV-CETDKWKYENPCKKMCTVSdYVSELYD------ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 167 QKTFKVKDKVQYEC--ATGYYtaggkKTEEVECLTyGWSLTPKCTKLKCSSLRLiENGYFHPVKQTYEEGDVVQFFCHEN 244
Cdd:PHA02954  88 KPLYEVNSTITLICkdETKYF-----RCEEKNGNT-SWNDTVTCPNAECQPLQL-EHGSCQPVKEKYSFGEHITINCDVG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 245 YYLSGSDLIQCYNFGWYPeSPVCEgrrNRCPPPPLpinSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCEDGKWTEP 324
Cdd:PHA02954 161 YEVIGASYISCTANSWNV-IPSCQ---QKCDIPSL---SNGLISGSTFSIGGVIHLSCKSGFTLTGSPSSTCIDGKWNPV 233

                        250
                 ....*....|
gi 767908640 325 -PKCIEGQEK 333
Cdd:PHA02954 234 lPICVRSNEE 243
PHA02831 PHA02831
EEV host range protein; Provisional
 352-513 1.75e-11

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 65.01  E-value: 1.75e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 352 KIYYNGDKVTYACKSGYllhGSNEITCNRGKWTLPPECVeNNENCKHPPVVMNGAVADGiLASYATGSSVEYRCN----E 427
Cdd:PHA02831  38 KVYEENENLEYKCNNNF---DKVFVTCNNGSWSTKNMCI-GKRNCKDPVTILNGYIKNK-KDQYSFGDSVTYACKvnklE 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 428 YYLLRGSKISRCEQGKW-SSPPVCLepcTVNVDYMNRNNIEMKwKYEGKVLHGDLIDFVCKQGYDLSpltplSELSVQCN 506
Cdd:PHA02831 113 KYSIVGNETVKCINKQWvPKYPVCK---LIRCKYPALQNGFLN-VFEKKFYYGDIVNFKCKKGFILL-----GSSVSTCD 183


                 ....*..
gi 767908640 507 RGEVKYP 513
Cdd:PHA02831 184 INSIWYP 190
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 274-328 5.39e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 58.24  E-value: 5.39e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767908640 274 CPPPPLPINSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRC-EDGKWT-EPPKCI 328
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 213-267 9.04e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.54  E-value: 9.04e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 767908640   213 CSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPVC 267
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGtWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 213-268 1.52e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 57.09  E-value: 1.52e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767908640 213 CSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCY-NFGWYPESPVCE 268
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 336-390 1.60e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 57.09  E-value: 1.60e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767908640 336 CEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNR-GKWT-LPPECV 390
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEnGGWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 336-389 2.50e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.38  E-value: 2.50e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 767908640   336 CEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITC-NRGKWTLP-PEC 389
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSPPpPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 274-327 9.27e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 54.84  E-value: 9.27e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 767908640   274 CPPPPLPINSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRC-EDGKWT-EPPKC 327
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSpPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 25-267 1.44e-09

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 60.10  E-value: 1.44e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640  25 CGFPHVENGRIAQYYYTFKSfyfpmsiDKKLSFFCLAGYTTesgrQEEQTTCTTEGWSPEPRCFKKCTKPDlsngYISDV 104
Cdd:PHA02954  21 CTVPTMNNAKLTSTETSFND-------KQKVTFTCDSGYYS----LDPNAVCETDKWKYENPCKKMCTVSD----YVSEL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 105 --KLLYKIQENMRYGCASGYKTTGGKDEEVvqclSDGWSSQPTCrkEHETCLAPELYNGNYSTTQKTFKVKDKVQYECAT 182
Cdd:PHA02954  86 ydKPLYEVNSTITLICKDETKYFRCEEKNG----NTSWNDTVTC--PNAECQPLQLEHGSCQPVKEKYSFGEHITINCDV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 183 GYYTAGGKKteeVECLTYGWSLTPKCTKlKCsSLRLIENGYFHpvKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFGWYP 262
Cdd:PHA02954 160 GYEVIGASY---ISCTANSWNVIPSCQQ-KC-DIPSLSNGLIS--GSTFSIGGVIHLSCKSGFTLTGSPSSTCIDGKWNP 232


                 ....*
gi 767908640 263 ESPVC 267
Cdd:PHA02954 233 VLPIC 237
Sushi pfam00084
Sushi repeat (SCR repeat);
213-267 1.93e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.66  E-value: 1.93e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767908640  213 CSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPVC 267
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGtWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 396-450 2.07e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.62  E-value: 2.07e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767908640 396 CKHPPVVMNGAVaDGILASYATGSSVEYRCNEYYLLRGSKISRC-EQGKWS-SPPVC 450
Cdd:cd00033    1 CPPPPVPENGTV-TGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSpPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 91-267 9.49e-09

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 57.37  E-value: 9.49e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640  91 CTKPD-LSNGYISDVKLLYKIQENMRYGCASGYKTTGGKDEEVVQCLSDG-WSSQPTCRKEHETCLAPELYNGNYSTTQK 168
Cdd:PHA02639  22 CDKPDdISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAiWSNKAPFCMLKECNDPPSIINGKIYNKRE 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 169 TFKVKDKVQYEC----ATGYYTAGgkkTEEVECLT-YGWSLTPKCTKLKCSSLRLIENGYFH--PVKQTYEEGDVVQFFC 241
Cdd:PHA02639 102 MYKVGDEIYYVCnehkGVQYSLVG---NEKITCIQdKSWKPDPPICKMINCRFPALQNGYINgiPSNKKFYYKTRVGFSC 178

                        170       180
                 ....*....|....*....|....*..
gi 767908640 242 HENYYLSGSDLIQC-YNFGWYPESPVC 267
Cdd:PHA02639 179 KSGFDLVGEKYSTCnINATWFPSIPTC 205
PHA02817 PHA02817
EEV Host range protein; Provisional
 272-393 2.33e-08

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 55.33  E-value: 2.33e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 272 NRCPPPPLPINSKIQTHSTTYRHGEIVHIECELN-----FEIHGSAEIRCE-DGKWT-EPPKCiegqEKVACEEPPfIEN 344
Cdd:PHA02817  22 NKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEkDGKWNkEFPVC----KIIRCRFPA-LQN 96

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 767908640 345 GAAN--LHSKIYYNGDKVTYACKSGYLLHGSNEITCNRGKWTLP--PECVENN 393
Cdd:PHA02817  97 GFVNgiPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPkvPICSRDN 149
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 524-578 4.06e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 50.15  E-value: 4.06e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767908640 524 CTSPPLIKHGVIISSTvDTYENGSSVEYRCFDHHFLEGSREAYCL-DGMWT-TPPLC 578
Cdd:cd00033    1 CPPPPVPENGTVTGSK-GSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 328-513 6.45e-08

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 54.67  E-value: 6.45e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 328 IEGQEKVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITC----NRGKWT-LPPECVEnnENCKHPPVV 402
Cdd:PHA02639  14 VHGVKSIYCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCikdkNNAIWSnKAPFCML--KECNDPPSI 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 403 MNGAVADGiLASYATGSSVEYRCNEY----YLLRGSKISRCEQGK-WS-SPPVC-LEPC---TVNVDYMNRNNIEMKWKY 472
Cdd:PHA02639  92 INGKIYNK-REMYKVGDEIYYVCNEHkgvqYSLVGNEKITCIQDKsWKpDPPICkMINCrfpALQNGYINGIPSNKKFYY 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 767908640 473 EGKVlhgdliDFVCKQGYDLspltpLSELSVQCNRGEVKYP 513
Cdd:PHA02639 171 KTRV------GFSCKSGFDL-----VGEKYSTCNINATWFP 200
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 354-578 1.23e-07

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 53.50  E-value: 1.23e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 354 YYNGDKVTYACKSGYLLH--GSNEITCNRGKWTLPPECVEnnENCKHPPVVMNGAVADGilaSYATGSSVEYRCNEYYLL 431
Cdd:PHA02927  44 YNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGWTLFNQCIK--RRCPSPRDIDNGQLDIG---GVDFGSSITYSCNSGYQL 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 432 RGSKISRCEQGKWSSppvclepctvnvdymnrnnieMKWkyegkvlhgdlidfvckqgydlSPLTPLSElSVQCNrgevk 511
Cdd:PHA02927 119 IGESKSYCELGSTGS---------------------MVW----------------------NPEAPICE-SVKCQ----- 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767908640 512 yplctrkeskgmctSPPLIKHGVIiSSTVDTYENGSSVEYRCFDHHFLEGSREAYCLDGMWTTPPLC 578
Cdd:PHA02927 150 --------------SPPSISNGRH-NGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTC 201
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 396-450 1.57e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 48.29  E-value: 1.57e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 767908640   396 CKHPPVVMNGAVADGIlASYATGSSVEYRCNEYYLLRGSKISRC-EQGKWS-SPPVC 450
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSpPPPTC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 208-275 2.97e-07

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 51.87  E-value: 2.97e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767908640 208 CTKLKCSSLRLIENGYFHPVKQTYEEGDVVQFFCHEN-----YYLSGSDLIQCYNFG-WYPESPVCEGRRNRCP 275
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGkWNKEFPVCKIIRCRFP 92
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 524-578 3.79e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 47.52  E-value: 3.79e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 767908640   524 CTSPPLIKHGVIISSTvDTYENGSSVEYRCFDHHFLEGSREAYCL-DGMWT-TPPLC 578
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
274-327 1.60e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.57  E-value: 1.60e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767908640  274 CPPPPLPINSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRC-EDGKWT-EPPKC 327
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCqEDGTWSpPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
336-389 2.49e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.18  E-value: 2.49e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 767908640  336 CEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITC-NRGKWTLP-PEC 389
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCqEDGTWSPPfPEC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 336-467 2.66e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 49.17  E-value: 2.66e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640 336 CEEPPFIENGAANLHSKIYYNGDKVTYACKSG-----YLLHGSNEITCNR-GKWTL-PPECveNNENCKHPpVVMNGAVa 408
Cdd:PHA02817  24 CCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKdGKWNKeFPVC--KIIRCRFP-ALQNGFV- 99

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767908640 409 DGILAS--YATGSSVEYRCNEYYLLRGSKISRCEQGKWSSP--PVCLE-PCTVNVDYMNRNNIE 467
Cdd:PHA02817 100 NGIPDSkkFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPkvPICSRdNITYNKIYINKVNID 163
PHA02817 PHA02817
EEV Host range protein; Provisional
 89-190 8.10e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 47.63  E-value: 8.10e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640  89 KKCTKPDLSNGYISDVKLLYKIQENMRYGCASG-----YKTTGgkdEEVVQCLSDG-WSSQPTcRKEHETCLAPELYNG- 161
Cdd:PHA02817  23 KCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVG---EKNIICEKDGkWNKEFP-VCKIIRCRFPALQNGf 98

                         90       100       110
                 ....*....|....*....|....*....|
gi 767908640 162 -NYSTTQKTFKVKDKVQYECATGYYTAGGK 190
Cdd:PHA02817  99 vNGIPDSKKFYYESEVSFSCKPGFVLIGTK 128
Sushi pfam00084
Sushi repeat (SCR repeat);
524-578 1.43e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.87  E-value: 1.43e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767908640  524 CTSPPLIKHGVIiSSTVDTYENGSSVEYRCFDHHFLEGSREAYCL-DGMWT-TPPLC 578
Cdd:pfam00084   1 CPPPPDIPNGKV-SATKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 75-188 2.27e-05

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 46.52  E-value: 2.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640  75 TCTTEGWSPEPRCFKK--CTKP-DLSNGYISDVKLLYKIQENMRYGCA----SGYKTTGgkdEEVVQCLSDGW-SSQPTC 146
Cdd:PHA02831  60 TCNNGSWSTKNMCIGKrnCKDPvTILNGYIKNKKDQYSFGDSVTYACKvnklEKYSIVG---NETVKCINKQWvPKYPVC 136

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 767908640 147 RKEHetCLAPELYNGNYSTTQKTFKVKDKVQYECATGYYTAG 188
Cdd:PHA02831 137 KLIR--CKYPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLG 176
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 28-126 3.73e-05

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 45.80  E-value: 3.73e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640  28 PHVENGRiaqyYYTFKSFYFPMSIdkkLSFFCLAGYTT--ESGrqeeqTTCTTEGWSPEPRC-FKKCTKPDLSNGYISD- 103
Cdd:PHA02927 152 PSISNGR----HNGYEDFYTDGSV---VTYSCNSGYSLigNSG-----VLCSGGEWSDPPTCqIVKCPHPTISNGYLSSg 219

                         90       100
                 ....*....|....*....|...
gi 767908640 104 VKLLYKIQENMRYGCASGYKTTG 126
Cdd:PHA02927 220 FKRSYSYNDNVDFKCKYGYKLSG 242
Sushi pfam00084
Sushi repeat (SCR repeat);
396-450 3.86e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 41.72  E-value: 3.86e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 767908640  396 CKHPPVVMNGAVAdGILASYATGSSVEYRCNEYYLLRGSKISRCEQ-GKWSSP-PVC 450
Cdd:pfam00084   1 CPPPPDIPNGKVS-ATKNEYNYGASVSYECDPGYRLVGSPTITCQEdGTWSPPfPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 94-147 2.74e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 39.37  E-value: 2.74e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 767908640  94 PDLSNGYISDVKLLYKIQENMRYGCASGYKTTGgkdEEVVQCLSDG-WS-SQPTCR 147
Cdd:cd00033    5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVG---SSTITCTENGgWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 94-146 4.79e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 38.66  E-value: 4.79e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 767908640    94 PDLSNGYISDVKLLYKIQENMRYGCASGYKTTGGkdeEVVQCLSDG-WS-SQPTC 146
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGS---STITCLENGtWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
153-208 5.61e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 38.25  E-value: 5.61e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767908640  153 CLAPE-LYNGNYSTTQKTFKVKDKVQYECATGYYTAGGkktEEVECLTYG-WS-LTPKC 208
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRLVGS---PTITCQEDGtWSpPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 156-208 6.19e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 38.21  E-value: 6.19e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 767908640 156 PELYNGNYSTTQKTFKVKDKVQYECATGYYTAGgkkTEEVECLTYG-WS-LTPKC 208
Cdd:cd00033    5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVG---SSTITCTENGgWSpPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 75-179 6.95e-04

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 42.38  E-value: 6.95e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767908640  75 TCTTEGWSPEPRCFKKCTKPDLSNGYISDVKllYKIQENMRYGCASGYKTTGGKDEevvQCLSDGWSS-QPTCRKEHETC 153
Cdd:PHA02954 170 SCTANSWNVIPSCQQKCDIPSLSNGLISGST--FSIGGVIHLSCKSGFTLTGSPSS---TCIDGKWNPvLPICVRSNEEF 244

                         90       100
                 ....*....|....*....|....*.
gi 767908640 154 LAPElyNGNYSTTQKTFKVKDKVQYE 179
Cdd:PHA02954 245 DPVD--DGPDDETDLSKLSKDVVQYE 268
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 156-208 8.00e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 37.89  E-value: 8.00e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 767908640   156 PELYNGNYSTTQKTFKVKDKVQYECATGYYTAGGkktEEVECLTYG-WS-LTPKC 208
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGS---STITCLENGtWSpPPPTC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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