|
Name |
Accession |
Description |
Interval |
E-value |
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
419-536 |
3.95e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
:
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.97 E-value: 3.95e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 419 DVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVVGTGSEVVAMTLETKPQRKN---QRTVLCHMaglQPGGHM 495
Cdd:smart00754 1 ETFSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPETAAHIHEGEIGTNgpvVRIPLPNP---TSREGP 77
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 755553121 496 AVGMCSGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVTA 536
Cdd:smart00754 78 FAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVAK 118
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
549-661 |
4.53e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
:
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.58 E-value: 4.53e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 549 LPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQgtvTAHL-LGPPGMPGPQR--LLKGF--YGSEAQ 623
Cdd:smart00754 3 FSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPET---AAHIhEGEIGTNGPVVriPLPNPtsREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 755553121 624 GVVKDLEPVLLRHLAQGTASLLITTKSSPRGELRGQVH 661
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
170-292 |
9.89e-13 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
:
Pssm-ID: 214804 Cd Length: 118 Bit Score: 65.83 E-value: 9.89e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 170 TDFVALLTG------PRSQAVARARVSLL-RSSLRFSVSYQRLDRPsrvrftdpTGNILFEHPATPTQDGLRRELRLRIA 242
Cdd:smart00754 1 ETFSALLTGsqevppVNTGAVGGAWFTLDdDGSLHYQVTLSGLSGP--------ETAAHIHEGEIGTNGPVVRIPLPNPT 72
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 755553121 243 ECDlfkviWLVCGVWRAVPRLSVRLLRAEQLRVALVTSTHPSGEVWGPLI 292
Cdd:smart00754 73 SRE-----GPFAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
300-413 |
1.79e-12 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
:
Pssm-ID: 214804 Cd Length: 118 Bit Score: 65.06 E-value: 1.79e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 300 ETFSAILTLE---DPLQRGVGGIALLTLsDTEDSLHFLLLFRGLLGGLAQAPLKL-QILHQGQLLRELQANTSAQEPGFA 375
Cdd:smart00754 1 ETFSALLTGSqevPPVNTGAVGGAWFTL-DDDGSLHYQVTLSGLSGPETAAHIHEgEIGTNGPVVRIPLPNPTSREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 755553121 376 EVLPSLTDQEMDWLELGELQMVLEKAGGPELRISGYIT 413
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
798-864 |
6.95e-07 |
|
von Willebrand factor (vWF) type C domain;
:
Pssm-ID: 214564 Cd Length: 59 Bit Score: 47.13 E-value: 6.95e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755553121 798 CYFDGDrsWRAAGTRWHPVVppfglikCAVCTCKGATgEVHCEKVQCPR-LACAQPVRANPTD-CCKQC 864
Cdd:smart00214 1 CVHNGR--VYNDGETWKPDP-------CQICTCLDGT-TVLCDPVECPPpPDCPNPERVKPPGeCCPRC 59
|
|
| VWC super family |
cl17735 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
51-125 |
2.80e-06 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
The actual alignment was detected with superfamily member pfam00093:
Pssm-ID: 450195 Cd Length: 57 Bit Score: 45.49 E-value: 2.80e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755553121 51 CSFGGKVYALDETWHPDLgepfgvmrCVLCACEapqwarrgrgPGRVSCKNIKpqCPTLACRQPR--QLPGHCCQTC 125
Cdd:pfam00093 1 CVQNGVVYENGETWKPDL--------CTICTCD----------DGKVLCDKII--CPPLDCPNPRleIPPGECCPVC 57
|
|
| VWC super family |
cl17735 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
886-946 |
3.32e-04 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
The actual alignment was detected with superfamily member pfam00093:
Pssm-ID: 450195 Cd Length: 57 Bit Score: 39.33 E-value: 3.32e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755553121 886 CRFAGQWFPENQSWHPSvppfgemSCITCRCGAGVPHCERDDCsPPLSCGSGKES----RCCSHC 946
Cdd:pfam00093 1 CVQNGVVYENGETWKPD-------LCTICTCDDGKVLCDKIIC-PPLDCPNPRLEippgECCPVC 57
|
|
| VWC super family |
cl17735 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
720-777 |
2.90e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
The actual alignment was detected with superfamily member pfam00093:
Pssm-ID: 450195 Cd Length: 57 Bit Score: 37.02 E-value: 2.90e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 720 CFFEGQQRPHGARWAPNydpLCSLCICQRRTVICDPVVCPPPSCPHP--VQALDQCCPVC 777
Cdd:pfam00093 1 CVQNGVVYENGETWKPD---LCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
419-536 |
3.95e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.97 E-value: 3.95e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 419 DVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVVGTGSEVVAMTLETKPQRKN---QRTVLCHMaglQPGGHM 495
Cdd:smart00754 1 ETFSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPETAAHIHEGEIGTNgpvVRIPLPNP---TSREGP 77
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 755553121 496 AVGMCSGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVTA 536
Cdd:smart00754 78 FAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVAK 118
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
549-661 |
4.53e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.58 E-value: 4.53e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 549 LPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQgtvTAHL-LGPPGMPGPQR--LLKGF--YGSEAQ 623
Cdd:smart00754 3 FSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPET---AAHIhEGEIGTNGPVVriPLPNPtsREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 755553121 624 GVVKDLEPVLLRHLAQGTASLLITTKSSPRGELRGQVH 661
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
pfam07452 |
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ... |
549-660 |
1.73e-14 |
|
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..
Pssm-ID: 462167 Cd Length: 118 Bit Score: 70.59 E-value: 1.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 549 LPVPLAGALVLPP-VRSQAAGHAWLSLDTHCH-LHYEVLLAGLggseQGTVTAHL-LGPPGMPGPQRL-----LKGFYGS 620
Cdd:pfam07452 1 FSALLTGAQEVPPpVTTGAGGTAVLTLDDTENtLHYTLTFSGL----SVPTAAHIhAGAAGFNGPVVVpleggPRKTTLL 76
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 755553121 621 EAQGVVKDLEPVLLRHLAQGTASLLIT--TKSSPRGELRGQV 660
Cdd:pfam07452 77 AVPEGLATLTAAQLAALLAQQGELYVNvhTEGNPGGEIRGQI 118
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
170-292 |
9.89e-13 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 65.83 E-value: 9.89e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 170 TDFVALLTG------PRSQAVARARVSLL-RSSLRFSVSYQRLDRPsrvrftdpTGNILFEHPATPTQDGLRRELRLRIA 242
Cdd:smart00754 1 ETFSALLTGsqevppVNTGAVGGAWFTLDdDGSLHYQVTLSGLSGP--------ETAAHIHEGEIGTNGPVVRIPLPNPT 72
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 755553121 243 ECDlfkviWLVCGVWRAVPRLSVRLLRAEQLRVALVTSTHPSGEVWGPLI 292
Cdd:smart00754 73 SRE-----GPFAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
300-413 |
1.79e-12 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 65.06 E-value: 1.79e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 300 ETFSAILTLE---DPLQRGVGGIALLTLsDTEDSLHFLLLFRGLLGGLAQAPLKL-QILHQGQLLRELQANTSAQEPGFA 375
Cdd:smart00754 1 ETFSALLTGSqevPPVNTGAVGGAWFTL-DDDGSLHYQVTLSGLSGPETAAHIHEgEIGTNGPVVRIPLPNPTSREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 755553121 376 EVLPSLTDQEMDWLELGELQMVLEKAGGPELRISGYIT 413
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
pfam07452 |
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ... |
421-534 |
3.44e-12 |
|
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..
Pssm-ID: 462167 Cd Length: 118 Bit Score: 64.04 E-value: 3.44e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 421 LQSVLCGADALIP-VQTGAAGSASFIL-LGNGSLIYQVQVVGTG--------------SEVVAMTLETKPQRKNQRTVlc 484
Cdd:pfam07452 1 FSALLTGAQEVPPpVTTGAGGTAVLTLdDTENTLHYTLTFSGLSvptaahihagaagfNGPVVVPLEGGPRKTTLLAV-- 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 755553121 485 hmaglqpgghmaVGMCSGLGARGAHMLLQN--ELFLNVGTKDFPDGELRGHV 534
Cdd:pfam07452 79 ------------PEGLATLTAAQLAALLAQqgELYVNVHTEGNPGGEIRGQI 118
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
798-864 |
6.95e-07 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 47.13 E-value: 6.95e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755553121 798 CYFDGDrsWRAAGTRWHPVVppfglikCAVCTCKGATgEVHCEKVQCPR-LACAQPVRANPTD-CCKQC 864
Cdd:smart00214 1 CVHNGR--VYNDGETWKPDP-------CQICTCLDGT-TVLCDPVECPPpPDCPNPERVKPPGeCCPRC 59
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
51-125 |
2.80e-06 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 45.49 E-value: 2.80e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755553121 51 CSFGGKVYALDETWHPDLgepfgvmrCVLCACEapqwarrgrgPGRVSCKNIKpqCPTLACRQPR--QLPGHCCQTC 125
Cdd:pfam00093 1 CVQNGVVYENGETWKPDL--------CTICTCD----------DGKVLCDKII--CPPLDCPNPRleIPPGECCPVC 57
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
886-946 |
3.32e-04 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 39.33 E-value: 3.32e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755553121 886 CRFAGQWFPENQSWHPSvppfgemSCITCRCGAGVPHCERDDCsPPLSCGSGKES----RCCSHC 946
Cdd:pfam00093 1 CVQNGVVYENGETWKPD-------LCTICTCDDGKVLCDKIIC-PPLDCPNPRLEippgECCPVC 57
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
720-777 |
2.90e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 37.02 E-value: 2.90e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 720 CFFEGQQRPHGARWAPNydpLCSLCICQRRTVICDPVVCPPPSCPHP--VQALDQCCPVC 777
Cdd:pfam00093 1 CVQNGVVYENGETWKPD---LCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
419-536 |
3.95e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.97 E-value: 3.95e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 419 DVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVVGTGSEVVAMTLETKPQRKN---QRTVLCHMaglQPGGHM 495
Cdd:smart00754 1 ETFSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPETAAHIHEGEIGTNgpvVRIPLPNP---TSREGP 77
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 755553121 496 AVGMCSGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVTA 536
Cdd:smart00754 78 FAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVAK 118
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
549-661 |
4.53e-26 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 103.58 E-value: 4.53e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 549 LPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQgtvTAHL-LGPPGMPGPQR--LLKGF--YGSEAQ 623
Cdd:smart00754 3 FSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPET---AAHIhEGEIGTNGPVVriPLPNPtsREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 755553121 624 GVVKDLEPVLLRHLAQGTASLLITTKSSPRGELRGQVH 661
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
pfam07452 |
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ... |
549-660 |
1.73e-14 |
|
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..
Pssm-ID: 462167 Cd Length: 118 Bit Score: 70.59 E-value: 1.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 549 LPVPLAGALVLPP-VRSQAAGHAWLSLDTHCH-LHYEVLLAGLggseQGTVTAHL-LGPPGMPGPQRL-----LKGFYGS 620
Cdd:pfam07452 1 FSALLTGAQEVPPpVTTGAGGTAVLTLDDTENtLHYTLTFSGL----SVPTAAHIhAGAAGFNGPVVVpleggPRKTTLL 76
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 755553121 621 EAQGVVKDLEPVLLRHLAQGTASLLIT--TKSSPRGELRGQV 660
Cdd:pfam07452 77 AVPEGLATLTAAQLAALLAQQGELYVNvhTEGNPGGEIRGQI 118
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
170-292 |
9.89e-13 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 65.83 E-value: 9.89e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 170 TDFVALLTG------PRSQAVARARVSLL-RSSLRFSVSYQRLDRPsrvrftdpTGNILFEHPATPTQDGLRRELRLRIA 242
Cdd:smart00754 1 ETFSALLTGsqevppVNTGAVGGAWFTLDdDGSLHYQVTLSGLSGP--------ETAAHIHEGEIGTNGPVVRIPLPNPT 72
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 755553121 243 ECDlfkviWLVCGVWRAVPRLSVRLLRAEQLRVALVTSTHPSGEVWGPLI 292
Cdd:smart00754 73 SRE-----GPFAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
smart00754 |
A domain in the BMP inhibitor chordin and in microbial proteins; |
300-413 |
1.79e-12 |
|
A domain in the BMP inhibitor chordin and in microbial proteins;
Pssm-ID: 214804 Cd Length: 118 Bit Score: 65.06 E-value: 1.79e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 300 ETFSAILTLE---DPLQRGVGGIALLTLsDTEDSLHFLLLFRGLLGGLAQAPLKL-QILHQGQLLRELQANTSAQEPGFA 375
Cdd:smart00754 1 ETFSALLTGSqevPPVNTGAVGGAWFTL-DDDGSLHYQVTLSGLSGPETAAHIHEgEIGTNGPVVRIPLPNPTSREGPFA 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 755553121 376 EVLPSLTDQEMDWLELGELQMVLEKAGGPELRISGYIT 413
Cdd:smart00754 80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
|
|
| CHRD |
pfam07452 |
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ... |
421-534 |
3.44e-12 |
|
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..
Pssm-ID: 462167 Cd Length: 118 Bit Score: 64.04 E-value: 3.44e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 421 LQSVLCGADALIP-VQTGAAGSASFIL-LGNGSLIYQVQVVGTG--------------SEVVAMTLETKPQRKNQRTVlc 484
Cdd:pfam07452 1 FSALLTGAQEVPPpVTTGAGGTAVLTLdDTENTLHYTLTFSGLSvptaahihagaagfNGPVVVPLEGGPRKTTLLAV-- 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 755553121 485 hmaglqpgghmaVGMCSGLGARGAHMLLQN--ELFLNVGTKDFPDGELRGHV 534
Cdd:pfam07452 79 ------------PEGLATLTAAQLAALLAQqgELYVNVHTEGNPGGEIRGQI 118
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
798-864 |
6.95e-07 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 47.13 E-value: 6.95e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 755553121 798 CYFDGDrsWRAAGTRWHPVVppfglikCAVCTCKGATgEVHCEKVQCPR-LACAQPVRANPTD-CCKQC 864
Cdd:smart00214 1 CVHNGR--VYNDGETWKPDP-------CQICTCLDGT-TVLCDPVECPPpPDCPNPERVKPPGeCCPRC 59
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
51-125 |
2.80e-06 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 45.49 E-value: 2.80e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755553121 51 CSFGGKVYALDETWHPDLgepfgvmrCVLCACEapqwarrgrgPGRVSCKNIKpqCPTLACRQPR--QLPGHCCQTC 125
Cdd:pfam00093 1 CVQNGVVYENGETWKPDL--------CTICTCD----------DGKVLCDKII--CPPLDCPNPRleIPPGECCPVC 57
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
886-946 |
3.32e-04 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 39.33 E-value: 3.32e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755553121 886 CRFAGQWFPENQSWHPSvppfgemSCITCRCGAGVPHCERDDCsPPLSCGSGKES----RCCSHC 946
Cdd:pfam00093 1 CVQNGVVYENGETWKPD-------LCTICTCDDGKVLCDKIIC-PPLDCPNPRLEippgECCPVC 57
|
|
| Amnionless |
pfam14828 |
Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for ... |
41-125 |
7.72e-04 |
|
Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for vitamin B12 uptake.
Pssm-ID: 464340 Cd Length: 449 Bit Score: 43.15 E-value: 7.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 41 EPLPVRGAagcSFGGKVYALDETWHPDLGEPFGVM----------------RCVLCAC---EAPQWArrgrgpgrvsCKN 101
Cdd:pfam14828 145 RPIRVKSV---SLLGQTFTSDEDFAEFLSSRLGQLqfhgagalrvgpeacsDPSGCGCgndENLERI----------CAN 211
|
90 100
....*....|....*....|....
gi 755553121 102 IKPQCPTLACRQPRQLPGHCCQTC 125
Cdd:pfam14828 212 VLQRCPPPHCLSPLRPEGHCCDVC 235
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
720-777 |
2.90e-03 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 37.02 E-value: 2.90e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 755553121 720 CFFEGQQRPHGARWAPNydpLCSLCICQRRTVICDPVVCPPPSCPHP--VQALDQCCPVC 777
Cdd:pfam00093 1 CVQNGVVYENGETWKPD---LCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
|
|
| |
