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Conserved domains on  [gi|755500092|ref|XP_011237954|]
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TLD domain-containing protein 2 isoform X8 [Mus musculus]

Protein Classification

TLD domain-containing protein( domain architecture ID 4815)

TLD domain-containing protein similar to Candida albicans oxidation resistance protein 1 (OXR1) and Pan troglodytes interferon-induced protein 44 (IFI44)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TLD super family cl02144
TLD; This domain is predicted to be an enzyme and is often found associated with pfam01476. It ...
 115-190 8.78e-27

TLD; This domain is predicted to be an enzyme and is often found associated with pfam01476. It's structure consists of a beta-sandwich surrounded by two helices and two one-turn helices.


The actual alignment was detected with superfamily member smart00584:

Pssm-ID: 445683  Cd Length: 165  Bit Score: 100.09  E-value: 8.78e-27
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755500092   115 PPRVTGHPWSLVFCTSRDGFSLRRLYRQMEGHSGPVLLLLRDQDGQMFGAFSSSAIRLSKGFYGTGETFLFSFSPQ 190
Cdd:smart00584  17 PTRAEGYPWTLLYSSSQHGYSLNTLYRKVEGYRPPTLLIIKDTDGEVFGAYASQAWRVSDHFYGTGESFLFQLNPK 92
 
Name Accession Description Interval E-value
TLDc smart00584
domain in TBC and LysM domain containing proteins;
115-190 8.78e-27

domain in TBC and LysM domain containing proteins;


Pssm-ID: 214733  Cd Length: 165  Bit Score: 100.09  E-value: 8.78e-27
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755500092   115 PPRVTGHPWSLVFCTSRDGFSLRRLYRQMEGHSGPVLLLLRDQDGQMFGAFSSSAIRLSKGFYGTGETFLFSFSPQ 190
Cdd:smart00584  17 PTRAEGYPWTLLYSSSQHGYSLNTLYRKVEGYRPPTLLIIKDTDGEVFGAYASQAWRVSDHFYGTGESFLFQLNPK 92
TLD pfam07534
TLD; This domain is predicted to be an enzyme and is often found associated with pfam01476. It ...
 125-203 8.17e-21

TLD; This domain is predicted to be an enzyme and is often found associated with pfam01476. It's structure consists of a beta-sandwich surrounded by two helices and two one-turn helices.


Pssm-ID: 429519  Cd Length: 139  Bit Score: 83.81  E-value: 8.17e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755500092  125 LVFCTSRDGFSLRRLYRQMEGHsGPVLLLLRDQDGQMFGAFSSSAIRLS-KGFYGTGETFLFSFSPQLKQCRPKleGKNP 203
Cdd:pfam07534   1 LLYSTSRDGSSYQTFLEKIDNK-GPTLLIIKDNDGYIFGAFASQPWKVSgKKFYGDGESFLFSLSPQFDPYKWT--GKNN 77
OXR1 COG5142
Oxidation resistance protein [DNA replication, recombination, and repair];
123-188 4.06e-11

Oxidation resistance protein [DNA replication, recombination, and repair];


Pssm-ID: 227471  Cd Length: 212  Bit Score: 59.91  E-value: 4.06e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755500092 123 WSLVFCTSRDGFSLRRLYRQMEGHSGPV-----LLLLRDQDGQMFGAFSSSAIRLSKGFYGTGETFLFSFS 188
Cdd:COG5142   59 WRLLYSLFENGFSLRTFYESFGENEWPFrrvgfVLACRDKDGDLFGAFFEDRIRPARHYYGRDEMFLWKAA 129
 
Name Accession Description Interval E-value
TLDc smart00584
domain in TBC and LysM domain containing proteins;
115-190 8.78e-27

domain in TBC and LysM domain containing proteins;


Pssm-ID: 214733  Cd Length: 165  Bit Score: 100.09  E-value: 8.78e-27
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755500092   115 PPRVTGHPWSLVFCTSRDGFSLRRLYRQMEGHSGPVLLLLRDQDGQMFGAFSSSAIRLSKGFYGTGETFLFSFSPQ 190
Cdd:smart00584  17 PTRAEGYPWTLLYSSSQHGYSLNTLYRKVEGYRPPTLLIIKDTDGEVFGAYASQAWRVSDHFYGTGESFLFQLNPK 92
TLD pfam07534
TLD; This domain is predicted to be an enzyme and is often found associated with pfam01476. It ...
 125-203 8.17e-21

TLD; This domain is predicted to be an enzyme and is often found associated with pfam01476. It's structure consists of a beta-sandwich surrounded by two helices and two one-turn helices.


Pssm-ID: 429519  Cd Length: 139  Bit Score: 83.81  E-value: 8.17e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755500092  125 LVFCTSRDGFSLRRLYRQMEGHsGPVLLLLRDQDGQMFGAFSSSAIRLS-KGFYGTGETFLFSFSPQLKQCRPKleGKNP 203
Cdd:pfam07534   1 LLYSTSRDGSSYQTFLEKIDNK-GPTLLIIKDNDGYIFGAFASQPWKVSgKKFYGDGESFLFSLSPQFDPYKWT--GKNN 77
OXR1 COG5142
Oxidation resistance protein [DNA replication, recombination, and repair];
123-188 4.06e-11

Oxidation resistance protein [DNA replication, recombination, and repair];


Pssm-ID: 227471  Cd Length: 212  Bit Score: 59.91  E-value: 4.06e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 755500092 123 WSLVFCTSRDGFSLRRLYRQMEGHSGPV-----LLLLRDQDGQMFGAFSSSAIRLSKGFYGTGETFLFSFS 188
Cdd:COG5142   59 WRLLYSLFENGFSLRTFYESFGENEWPFrrvgfVLACRDKDGDLFGAFFEDRIRPARHYYGRDEMFLWKAA 129
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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