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Conserved domains on  [gi|578820869|ref|XP_006718411|]
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1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X7 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN02450 super family cl30161
1-aminocyclopropane-1-carboxylate synthase
 45-317 7.65e-52

1-aminocyclopropane-1-carboxylate synthase


The actual alignment was detected with superfamily member PLN02450:

Pssm-ID: 178069 [Multi-domain]  Cd Length: 468  Bit Score: 177.25  E-value: 7.65e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  45 FQLTVEKLEMALREAHSEGVKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEkSVGYRSVLsl 124
Cdd:PLN02450 171 FQITESALEEAYQQAQKLNLKVKGVLITNPSNPLGTTTTRTELNLLVDFITAKNIHLISDEIYSGTVFD-SPGFVSVM-- 247

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 125 ERLPDPQ--------RTHVMWATSKDFGMSGLRFGTLYTENQDVATAVASLCRYHGLSGLVQYQMAQLLRDRDWINQvYL 196
Cdd:PLN02450 248 EVLKDRKlentdvsnRVHIVYSLSKDLGLPGFRVGAIYSNDEMVVSAATKMSSFGLVSSQTQYLLSALLSDKKFTKN-YL 326

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 197 PENHARLKAAHTYVSEELRALGIPFLSRGAGFFIWVDLRKYLPKGTFEEEMLLWRRFL-DNKVLLSFGKAFECKEPGWFR 275
Cdd:PLN02450 327 EENQKRLKQRQKKLVSGLEAAGIKCLKSNAGLFCWVDMRHLLKSNTFEAEMELWKKIVyEVKLNISPGSSCHCTEPGWFR 406

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 578820869 276 FVFSDQVHR-LCLGMQRVqqvlagKSQVAEDPRPSQSQEPSDQ 317
Cdd:PLN02450 407 VCFANMSEEtLDLAMKRL------KSFVESDSGRRINKSSHQR 443
 
Name Accession Description Interval E-value
PLN02450 PLN02450
1-aminocyclopropane-1-carboxylate synthase
 45-317 7.65e-52

1-aminocyclopropane-1-carboxylate synthase


Pssm-ID: 178069 [Multi-domain]  Cd Length: 468  Bit Score: 177.25  E-value: 7.65e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  45 FQLTVEKLEMALREAHSEGVKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEkSVGYRSVLsl 124
Cdd:PLN02450 171 FQITESALEEAYQQAQKLNLKVKGVLITNPSNPLGTTTTRTELNLLVDFITAKNIHLISDEIYSGTVFD-SPGFVSVM-- 247

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 125 ERLPDPQ--------RTHVMWATSKDFGMSGLRFGTLYTENQDVATAVASLCRYHGLSGLVQYQMAQLLRDRDWINQvYL 196
Cdd:PLN02450 248 EVLKDRKlentdvsnRVHIVYSLSKDLGLPGFRVGAIYSNDEMVVSAATKMSSFGLVSSQTQYLLSALLSDKKFTKN-YL 326

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 197 PENHARLKAAHTYVSEELRALGIPFLSRGAGFFIWVDLRKYLPKGTFEEEMLLWRRFL-DNKVLLSFGKAFECKEPGWFR 275
Cdd:PLN02450 327 EENQKRLKQRQKKLVSGLEAAGIKCLKSNAGLFCWVDMRHLLKSNTFEAEMELWKKIVyEVKLNISPGSSCHCTEPGWFR 406

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 578820869 276 FVFSDQVHR-LCLGMQRVqqvlagKSQVAEDPRPSQSQEPSDQ 317
Cdd:PLN02450 407 VCFANMSEEtLDLAMKRL------KSFVESDSGRRINKSSHQR 443
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 12-294 1.03e-43

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 152.88  E-value: 1.03e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  12 RCCVRPGHVCL-----YGNIRLAYVYLDSEVTGLDTRP---FQLTVEKLEMALREahsegvKVKGLILISPQNPLGDVYS 83
Cdd:cd00609   77 RALLNPGDEVLvpdptYPGYEAAARLAGAEVVPVPLDEeggFLLDLELLEAAKTP------KTKLLYLNNPNNPTGAVLS 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  84 PEELQEYLVFAKRHRLHVIVDEVYMLSVFEKSVgyrsVLSLERLPDPQRTHVMWATSKDFGMSGLRFGTLYTENQDVATA 163
Cdd:cd00609  151 EEELEELAELAKKHGILIISDEAYAELVYDGEP----PPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLER 226

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 164 VASLCRY--HGLSGLVQYQMAQLLRDRdwinQVYLPENHARLKAAHTYVSEELRALGIPFLSRG-AGFFIWVDLRKYlpk 240
Cdd:cd00609  227 LKKLLPYttSGPSTLSQAAAAAALDDG----EEHLEELRERYRRRRDALLEALKELGPLVVVKPsGGFFLWLDLPEG--- 299

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 578820869 241 gtfEEEMLLWRRFLDNKVLLSFGKAFECKEPGWFRFVFSDQVHRLCLGMQRVQQ 294
Cdd:cd00609  300 ---DDEEFLERLLLEAGVVVRPGSAFGEGGEGFVRLSFATPEEELEEALERLAE 350
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
45-286 5.68e-37

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 135.13  E-value: 5.68e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869   45 FQLTVEKLEMALREAHsegvkvKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKSVGYRSVLSL 124
Cdd:pfam00155 122 FHLDFDALEAALKEKP------KVVLHTSPHNPTGTVATLEELEKLLDLAKEHNILLLVDEAYAGFVFGSPDAVATRALL 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  125 ERLPDpqrTHVMWATSKDFGMSGLRFGTLYTeNQDVATAVASLCRYHGLSGLVQYQMAQLLRDRDWINQvYLPENHARLK 204
Cdd:pfam00155 196 AEGPN---LLVVGSFSKAFGLAGWRVGYILG-NAAVISQLRKLARPFYSSTHLQAAAAAALSDPLLVAS-ELEEMRQRIK 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  205 AAHTYVSEELRALGIPFLSRGAGFFIWVDLRKylpkgtfEEEMLLWRRFLDN-KVLLSFGKAFECkePGWFRFVFS---- 279
Cdd:pfam00155 271 ERRDYLRDGLQAAGLSVLPSQAGFFLLTGLDP-------ETAKELAQVLLEEvGVYVTPGSSPGV--PGWLRITVAggte 341


                  ....*..
gi 578820869  280 DQVHRLC 286
Cdd:pfam00155 342 EELEELL 348
AspB COG0436
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
 17-297 2.29e-33

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 126.40  E-value: 2.29e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  17 PGHVCLYGNIRLAyvylDSEVTGLDTRP---FQLTVEKLEMALREahsegvKVKGLILISPQNPLGDVYSPEELQEYLVF 93
Cdd:COG0436  122 PGYPSYRAAVRLA----GGKPVPVPLDEengFLPDPEALEAAITP------RTKAIVLNSPNNPTGAVYSREELEALAEL 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  94 AKRHRLHVIVDEVYMLSVFEKsVGYRSVLSLERLPDpqRTHVMWATSKDFGMSGLRFGTLYTeNQDVATAVASLCRYHGL 173
Cdd:COG0436  192 AREHDLLVISDEIYEELVYDG-AEHVSILSLPGLKD--RTIVINSFSKSYAMTGWRIGYAVG-PPELIAALLKLQSNLTS 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 174 S--GLVQYQMAQLLRDRdwinQVYLPENHARLKAAHTYVSEELRALGIPFLSRGAGFFIWVDLRKYLPKGT-FEEEMLlw 250
Cdd:COG0436  268 CapTPAQYAAAAALEGP----QDYVEEMRAEYRRRRDLLVEGLNEIGLSVVKPEGAFYLFADVPELGLDSEeFAERLL-- 341

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 578820869 251 rrfLDNKVLLSFGKAFECKEPGWFRFVFSDQVHRLCLGMQRVQQVLA 297
Cdd:COG0436  342 ---EEAGVAVVPGSAFGPAGEGYVRISYATSEERLEEALERLARFLE 385
tyr_amTase_E TIGR01264
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ...
 16-277 3.57e-08

tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]


Pssm-ID: 273529 [Multi-domain]  Cd Length: 401  Bit Score: 54.40  E-value: 3.57e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869   16 RPGhVCLYGNIRLAYvyldsevtGLDTRPFQLTVEK-LEMALREAHS-EGVKVKGLILISPQNPLGDVYSPEELQEYLVF 93
Cdd:TIGR01264 126 RPG-FPLYETLAESM--------GIEVKLYNLLPDKsWEIDLKQLESlIDEKTAALIVNNPSNPCGSVFSRQHLEEILAV 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869   94 AKRHRLHVIVDEVYMLSVFEKSVgYRSVLSLErlPDPQRThVMWATSKDFGMSGLRFGTLYTENQ-----DVATAVASLC 168
Cdd:TIGR01264 197 AERQCLPIIADEIYGDMVFSGAT-FEPLASLS--STVPIL-SCGGLAKRWLVPGWRLGWIIIHDRrgilrDIRDGLVKLS 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  169 -RYHGLSGLVQYQMAQLLRDRDwinQVYLPENHARLKAAHTYVSEELRAL-GI-PFLSRGAGF-FIWVDLRKYlpkGTFE 244
Cdd:TIGR01264 273 qRILGPCTIVQGALPSILLRTP---QEYFDGTLSVLESNAMLCYGALAAVpGLrPVMPSGAMYmMVGIEMEHF---PEFK 346

                         250       260       270
                  ....*....|....*....|....*....|....
gi 578820869  245 EEMLLWRRFL-DNKVLLSFGKAFECkePGWFRFV 277
Cdd:TIGR01264 347 NDVEFTERLVaEQSVFCLPGSCFEY--PGFFRVV 378
 
Name Accession Description Interval E-value
PLN02450 PLN02450
1-aminocyclopropane-1-carboxylate synthase
 45-317 7.65e-52

1-aminocyclopropane-1-carboxylate synthase


Pssm-ID: 178069 [Multi-domain]  Cd Length: 468  Bit Score: 177.25  E-value: 7.65e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  45 FQLTVEKLEMALREAHSEGVKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEkSVGYRSVLsl 124
Cdd:PLN02450 171 FQITESALEEAYQQAQKLNLKVKGVLITNPSNPLGTTTTRTELNLLVDFITAKNIHLISDEIYSGTVFD-SPGFVSVM-- 247

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 125 ERLPDPQ--------RTHVMWATSKDFGMSGLRFGTLYTENQDVATAVASLCRYHGLSGLVQYQMAQLLRDRDWINQvYL 196
Cdd:PLN02450 248 EVLKDRKlentdvsnRVHIVYSLSKDLGLPGFRVGAIYSNDEMVVSAATKMSSFGLVSSQTQYLLSALLSDKKFTKN-YL 326

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 197 PENHARLKAAHTYVSEELRALGIPFLSRGAGFFIWVDLRKYLPKGTFEEEMLLWRRFL-DNKVLLSFGKAFECKEPGWFR 275
Cdd:PLN02450 327 EENQKRLKQRQKKLVSGLEAAGIKCLKSNAGLFCWVDMRHLLKSNTFEAEMELWKKIVyEVKLNISPGSSCHCTEPGWFR 406

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 578820869 276 FVFSDQVHR-LCLGMQRVqqvlagKSQVAEDPRPSQSQEPSDQ 317
Cdd:PLN02450 407 VCFANMSEEtLDLAMKRL------KSFVESDSGRRINKSSHQR 443
PLN02607 PLN02607
1-aminocyclopropane-1-carboxylate synthase
 45-303 5.92e-48

1-aminocyclopropane-1-carboxylate synthase


Pssm-ID: 215327 [Multi-domain]  Cd Length: 447  Bit Score: 166.60  E-value: 5.92e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  45 FQLTVEKLEMALREAHSEGVKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKS--VGYRSVL 122
Cdd:PLN02607 180 FQVTPQALEAAYQEAEAANIRVRGVLITNPSNPLGATVQRSVLEDILDFVVRKNIHLVSDEIYSGSVFSASefVSVAEIV 259

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 123 SLERLPDP-QRTHVMWATSKDFGMSGLRFGTLYTENQDVATAVASLCRYHGLSGLVQYQMAQLLRDRDWiNQVYLPENHA 201
Cdd:PLN02607 260 EARGYKGVaERVHIVYSLSKDLGLPGFRVGTIYSYNDKVVTTARRMSSFTLVSSQTQHLLASMLSDEEF-TENYIRTNRE 338

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 202 RLKAAHTYVSEELRALGIPFLSRGAGFFIWVDLRKYLPKGTFEEEMLLWRRFL-DNKVLLSFGKAFECKEPGWFRFVFSD 280
Cdd:PLN02607 339 RLRKRYEMIVQGLRRAGIECLKGNAGLFCWMNLSPLLETPTREGELALWDSILrEVKLNISPGSSCHCSEPGWFRVCFAN 418

                        250       260
                 ....*....|....*....|....
gi 578820869 281 -QVHRLCLGMQRVQQVLAGKSQVA 303
Cdd:PLN02607 419 mSEDTLEVALKRIHRFMDRRKTAS 442
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
 12-294 1.03e-43

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 152.88  E-value: 1.03e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  12 RCCVRPGHVCL-----YGNIRLAYVYLDSEVTGLDTRP---FQLTVEKLEMALREahsegvKVKGLILISPQNPLGDVYS 83
Cdd:cd00609   77 RALLNPGDEVLvpdptYPGYEAAARLAGAEVVPVPLDEeggFLLDLELLEAAKTP------KTKLLYLNNPNNPTGAVLS 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  84 PEELQEYLVFAKRHRLHVIVDEVYMLSVFEKSVgyrsVLSLERLPDPQRTHVMWATSKDFGMSGLRFGTLYTENQDVATA 163
Cdd:cd00609  151 EEELEELAELAKKHGILIISDEAYAELVYDGEP----PPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLER 226

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 164 VASLCRY--HGLSGLVQYQMAQLLRDRdwinQVYLPENHARLKAAHTYVSEELRALGIPFLSRG-AGFFIWVDLRKYlpk 240
Cdd:cd00609  227 LKKLLPYttSGPSTLSQAAAAAALDDG----EEHLEELRERYRRRRDALLEALKELGPLVVVKPsGGFFLWLDLPEG--- 299

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 578820869 241 gtfEEEMLLWRRFLDNKVLLSFGKAFECKEPGWFRFVFSDQVHRLCLGMQRVQQ 294
Cdd:cd00609  300 ---DDEEFLERLLLEAGVVVRPGSAFGEGGEGFVRLSFATPEEELEEALERLAE 350
PLN02376 PLN02376
1-aminocyclopropane-1-carboxylate synthase
 13-304 4.95e-40

1-aminocyclopropane-1-carboxylate synthase


Pssm-ID: 178004 [Multi-domain]  Cd Length: 496  Bit Score: 146.38  E-value: 4.95e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  13 CCVRPGHVCLYGNIRlaYVYLDSEV---TGLDTRP--------FQLTVEKLEMALREAHSEGVKVKGLILISPQNPLGDV 81
Cdd:PLN02376 138 CLADPGDVFLIPSPY--YAAFDRDLrwrTGVEIIPvpcsssdnFKLTVDAADWAYKKAQESNKKVKGLILTNPSNPLGTM 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  82 YSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKSvGYRSVLSLERLPDPQRT-----HVMWATSKDFGMSGLRFGTLYTE 156
Cdd:PLN02376 216 LDKDTLTNLVRFVTRKNIHLVVDEIYAATVFAGG-DFVSVAEVVNDVDISEVnvdliHIVYSLSKDMGLPGFRVGIVYSF 294

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 157 NQDVATAVASLCRYHGLSGLVQYQMAQLLRDRDWINQvYLPENHARLKAAHTYVSEELRALGIPFLSRGAGFFIWVDLRK 236
Cdd:PLN02376 295 NDSVVSCARKMSSFGLVSSQTQLMLASMLSDDQFVDN-FLMESSRRLGIRHKVFTTGIKKADIACLTSNAGLFAWMDLRH 373

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578820869 237 YL-PKGTFEEEMLLWRRFLDN-KVLLSFGKAFECKEPGWFRFVFS----DQVHrlcLGMQRVQQVLA-GKSQVAE 304
Cdd:PLN02376 374 LLrDRNSFESEIELWHIIIDKvKLNVSPGSSFRCTEPGWFRICFAnmddDTLH---VALGRIQDFVSkNKNKIVE 445
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
45-286 5.68e-37

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 135.13  E-value: 5.68e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869   45 FQLTVEKLEMALREAHsegvkvKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKSVGYRSVLSL 124
Cdd:pfam00155 122 FHLDFDALEAALKEKP------KVVLHTSPHNPTGTVATLEELEKLLDLAKEHNILLLVDEAYAGFVFGSPDAVATRALL 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  125 ERLPDpqrTHVMWATSKDFGMSGLRFGTLYTeNQDVATAVASLCRYHGLSGLVQYQMAQLLRDRDWINQvYLPENHARLK 204
Cdd:pfam00155 196 AEGPN---LLVVGSFSKAFGLAGWRVGYILG-NAAVISQLRKLARPFYSSTHLQAAAAAALSDPLLVAS-ELEEMRQRIK 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  205 AAHTYVSEELRALGIPFLSRGAGFFIWVDLRKylpkgtfEEEMLLWRRFLDN-KVLLSFGKAFECkePGWFRFVFS---- 279
Cdd:pfam00155 271 ERRDYLRDGLQAAGLSVLPSQAGFFLLTGLDP-------ETAKELAQVLLEEvGVYVTPGSSPGV--PGWLRITVAggte 341


                  ....*..
gi 578820869  280 DQVHRLC 286
Cdd:pfam00155 342 EELEELL 348
AspB COG0436
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
 17-297 2.29e-33

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 126.40  E-value: 2.29e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  17 PGHVCLYGNIRLAyvylDSEVTGLDTRP---FQLTVEKLEMALREahsegvKVKGLILISPQNPLGDVYSPEELQEYLVF 93
Cdd:COG0436  122 PGYPSYRAAVRLA----GGKPVPVPLDEengFLPDPEALEAAITP------RTKAIVLNSPNNPTGAVYSREELEALAEL 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  94 AKRHRLHVIVDEVYMLSVFEKsVGYRSVLSLERLPDpqRTHVMWATSKDFGMSGLRFGTLYTeNQDVATAVASLCRYHGL 173
Cdd:COG0436  192 AREHDLLVISDEIYEELVYDG-AEHVSILSLPGLKD--RTIVINSFSKSYAMTGWRIGYAVG-PPELIAALLKLQSNLTS 267

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 174 S--GLVQYQMAQLLRDRdwinQVYLPENHARLKAAHTYVSEELRALGIPFLSRGAGFFIWVDLRKYLPKGT-FEEEMLlw 250
Cdd:COG0436  268 CapTPAQYAAAAALEGP----QDYVEEMRAEYRRRRDLLVEGLNEIGLSVVKPEGAFYLFADVPELGLDSEeFAERLL-- 341

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 578820869 251 rrfLDNKVLLSFGKAFECKEPGWFRFVFSDQVHRLCLGMQRVQQVLA 297
Cdd:COG0436  342 ---EEAGVAVVPGSAFGPAGEGYVRISYATSEERLEEALERLARFLE 385
PRK05764 PRK05764
aspartate aminotransferase; Provisional
 16-300 1.41e-17

aspartate aminotransferase; Provisional


Pssm-ID: 235596  Cd Length: 393  Bit Score: 82.48  E-value: 1.41e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  16 RPGHVClYGN-IRLAY---VYLDsevTGLDTRpFQLTVEKLEMALREahsegvKVKGLILISPQNPLGDVYSPEELQEYL 91
Cdd:PRK05764 122 APYWVS-YPEmVKLAGgvpVFVP---TGEENG-FKLTVEQLEAAITP------KTKALILNSPSNPTGAVYSPEELEAIA 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  92 VFAKRHRLHVIVDEVYMLSVFEKSVGYRSVLSLERLPDpqRTHVMWATSKDFGMSGLRFGTLyTENQDVATAVASLCRyH 171
Cdd:PRK05764 191 DVAVEHDIWVLSDEIYEKLVYDGAEFTSIASLSPELRD--RTITVNGFSKAYAMTGWRLGYA-AGPKELIKAMSKLQS-H 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 172 GLSG---LVQY-QMAQLLRDRDWINqvylpENHARLKAAHTYVSEELRAL-GIPFL-SRGAgFFIWVDLRKYLPKgTFEE 245
Cdd:PRK05764 267 STSNptsIAQYaAVAALNGPQDEVE-----EMRQAFEERRDLMVDGLNEIpGLECPkPEGA-FYVFPNVSKLLGK-SITD 339

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 578820869 246 EMLLWRRFLDN-KVLLSFGKAFecKEPGWFRFVFSDQVHRLCLGMQRVQQVLAGKS 300
Cdd:PRK05764 340 SLEFAEALLEEaGVAVVPGIAF--GAPGYVRLSYATSLEDLEEGLERIERFLESLK 393
MalY COG1168
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ...
 50-278 8.29e-17

Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440782  Cd Length: 387  Bit Score: 80.14  E-value: 8.29e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  50 EKLEMALREahsegvKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEksvGYR--SVLSLErl 127
Cdd:COG1168  152 DDLEAKLDP------GVKLLLLCNPHNPTGRVWTREELERLAELCERHDVLVISDEIHADLVLP---GHKhtPFASLS-- 220

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 128 PD-PQRTHVMWATSKDFGMSGLRFGTLYTENQDVATAVASLCRYHGLS-----GLVQYQMAqlLRD-RDWINQV--YLPE 198
Cdd:COG1168  221 EEaADRTITLTSPSKTFNLAGLKASYAIIPNPALRARFARALEGLGLPspnvlGLVATEAA--YREgEEWLDELlaYLRG 298

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 199 NHARLKAahtYVSEELRalGIPFLSRGAGFFIWVDLRKYlpkGTFEEEmlLWRRFLDN-KVLLSFGKAFECKEPGWFRFV 277
Cdd:COG1168  299 NRDLLAE---FLAEHLP--GVKVTPPEATYLAWLDCRAL---GLDDEE--LAEFLLEKaGVALSDGATFGEGGEGFVRLN 368


                 .
gi 578820869 278 F 278
Cdd:COG1168  369 F 369
HisC COG0079
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ...
 42-276 1.18e-16

Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 439849 [Multi-domain]  Cd Length: 341  Bit Score: 79.41  E-value: 1.18e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  42 TRPFQLTVEKLEMALREahsegvKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLhVIVDEVYMlsvfEKSVGYRSV 121
Cdd:COG0079  119 DEDFSLDLDALLAAITE------RTDLVFLCNPNNPTGTLLPREELEALLEALPADGL-VVVDEAYA----EFVPEEDSA 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 122 LSLerLPDPQRTHVMWATSKDFGMSGLRFGTLYTeNQDVATAVASLCRYHGLSGLVQYQMAQLLRDRDWINqvylpENHA 201
Cdd:COG0079  188 LPL--LARYPNLVVLRTFSKAYGLAGLRLGYAIA-SPELIAALRRVRGPWNVNSLAQAAALAALEDRAYLE-----ETRA 259

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578820869 202 RLKAAHTYVSEELRALGIPFLsRGAGFFIWVDlrkylpkgTFEEEMLLWRRFLDNKVLLSFGKAFECkePGWFRF 276
Cdd:COG0079  260 RLRAERERLAAALRALGLTVY-PSQANFVLVR--------VPEDAAELFEALLERGILVRDFSSFGL--PDYLRI 323
PRK07568 PRK07568
pyridoxal phosphate-dependent aminotransferase;
65-168 7.28e-16

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181036  Cd Length: 397  Bit Score: 77.58  E-value: 7.28e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  65 KVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKSVgYRSVLSLERLPDpqRTHVMWATSKDFG 144
Cdd:PRK07568 162 KTKAILISNPGNPTGVVYTKEELEMLAEIAKKHDLFLISDEVYREFVYDGLK-YTSALSLEGLED--RVIIIDSVSKRYS 238

                         90       100
                 ....*....|....*....|....
gi 578820869 145 MSGLRFGTLYTENQDVATAVASLC 168
Cdd:PRK07568 239 ACGARIGCLISKNKELIAAAMKLC 262
PRK07682 PRK07682
aminotransferase;
45-151 8.62e-15

aminotransferase;


Pssm-ID: 181082 [Multi-domain]  Cd Length: 378  Bit Score: 74.00  E-value: 8.62e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  45 FQLTVEKLEMALREahsegvKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKSvgYRSVLSL 124
Cdd:PRK07682 140 FKVQPAQIEAAITA------KTKAILLCSPNNPTGAVLNKSELEEIAVIVEKHDLIVLSDEIYAELTYDEA--YTSFASI 211

                         90       100
                 ....*....|....*....|....*..
gi 578820869 125 ERLPDpqRTHVMWATSKDFGMSGLRFG 151
Cdd:PRK07682 212 KGMRE--RTILISGFSKGFAMTGWRLG 236
PRK06348 PRK06348
pyridoxal phosphate-dependent aminotransferase;
45-275 1.94e-13

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180537  Cd Length: 384  Bit Score: 70.13  E-value: 1.94e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  45 FQLTVEKLEMALREahsegvKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKSvgYRSVLSL 124
Cdd:PRK06348 148 FQINVKKLEALITS------KTKAIILNSPNNPTGAVFSKETLEEIAKIAIEYDLFIISDEVYDGFSFYED--FVPMATL 219

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 125 ERLPDpqRTHVMWATSKDFGMSGLRFG----------TLYTENQDVATAVASLCRYHGLSGlvqyqmaqlLRDRDWINQV 194
Cdd:PRK06348 220 AGMPE--RTITFGSFSKDFAMTGWRIGyviapdyiieTAKIINEGICFSAPTISQRAAIYA---------LKHRDTIVPL 288

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 195 YLPENHARLKaahtYVSEELRAlgIPFLS---RGAGFFIWVDLRKY-LPKGTFEEEMLlwrrfLDNKVLLSFGKAF-ECK 269
Cdd:PRK06348 289 IKEEFQKRLE----YAYKRIES--IPNLSlhpPKGSIYAFINIKKTgLSSVEFCEKLL-----KEAHVLVIPGKAFgESG 357


                 ....*.
gi 578820869 270 EpGWFR 275
Cdd:PRK06348 358 E-GYIR 362
PRK07309 PRK07309
pyridoxal phosphate-dependent aminotransferase;
30-297 5.62e-13

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235985  Cd Length: 391  Bit Score: 68.98  E-value: 5.62e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  30 YVYLDSEVTGldtrpFQLTVEKLEMALREahsEGVKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMl 109
Cdd:PRK07309 139 IVEIDTTEND-----FVLTPEMLEKAILE---QGDKLKAVILNYPANPTGVTYSREQIKALADVLKKYDIFVISDEVYS- 209

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 110 svfEKSVGYRSVLSL-ERLPDpqRTHVMWATSKDFGMSGLRFGTLYTENQDVA----------TAVASLCRYHGLSGL-- 176
Cdd:PRK07309 210 ---ELTYTGEPHVSIaEYLPD--QTILINGLSKSHAMTGWRIGLIFAPAEFTAqlikshqylvTAATTMAQFAAVEALtn 284

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 177 ----VQYQMAQLLRDRDwinqvylpenharlkaahtYVSEELRALGIPFLSRGAGFFIWVDlrkyLPKGTFEEEMLLWRR 252
Cdd:PRK07309 285 gkddALPMKKEYIKRRD-------------------YIIEKMTDLGFKIIKPDGAFYIFAK----IPAGYNQDSFKFLQD 341

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 578820869 253 FL-DNKVLLSFGKAFECKEPGWFRFVFSDQVHRLCLGMQRVQQVLA 297
Cdd:PRK07309 342 FArKKAVAFIPGAAFGPYGEGYVRLSYAASMETIKEAMKRLKEYME 387
PRK07683 PRK07683
aminotransferase A; Validated
 26-301 1.14e-11

aminotransferase A; Validated


Pssm-ID: 236075  Cd Length: 387  Bit Score: 64.75  E-value: 1.14e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  26 IRLAY---VYLDSEVTGldtrpFQLTVEKLEMALREahsegvKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVI 102
Cdd:PRK07683 130 IRLCGakpVFIDTRSTG-----FRLTAEALENAITE------KTRCVVLPYPSNPTGVTLSKEELQDIADVLKDKNIFVL 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 103 VDEVYMLSVFEKSvgYRSVLSLERLPDpqRTHVMWATSKDFGMSGLRFGTLYTE----------NQDVATAVASLCRYHG 172
Cdd:PRK07683 199 SDEIYSELVYEQP--HTSIAHFPEMRE--KTIVINGLSKSHSMTGWRIGFLFAPsylakhilkvHQYNVTCASSISQYAA 274

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 173 LSGL-VQYQMAQLLRDrdwinqvylpENHARLKaahtYVSEELRALGIPFLSRGAGFFIWVDLRKYlPKGTFEEEMLLWR 251
Cdd:PRK07683 275 LEALtAGKDDAKMMRH----------QYKKRRD----YVYNRLISMGLDVEKPTGAFYLFPSIGHF-TMSSFDFALDLVE 339

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 578820869 252 rflDNKVLLSFGKAFECKEPGWFRFVFSDQVHRLCLGMQRVQQVLAGKSQ 301
Cdd:PRK07683 340 ---EAGLAVVPGSAFSEYGEGYVRLSYAYSIETLKEGLDRLEAFLQQKAK 386
PRK06108 PRK06108
pyridoxal phosphate-dependent aminotransferase;
45-297 1.90e-11

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180404  Cd Length: 382  Bit Score: 64.19  E-value: 1.90e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  45 FQLTVEKLEMALREahsegvKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKSVGYRSVLSL 124
Cdd:PRK06108 144 WTLDLDRLLAAITP------RTRALFINSPNNPTGWTASRDDLRAILAHCRRHGLWIVADEVYERLYYAPGGRAPSFLDI 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 125 ERlPDpQRTHVMWATSKDFGMSGLRFGTLytenqdvaTAVASLCRyhGLSGLVQY---------QMAQL--LRDRDwinq 193
Cdd:PRK06108 218 AE-PD-DRIIFVNSFSKNWAMTGWRLGWL--------VAPPALGQ--VLEKLIEYntscvaqfvQRAAVaaLDEGE---- 281

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 194 VYLPENHARLKAAHTYVSEELRALGipflsrgagffiWVDLRKylPKGTF---------EEEMLLWRRFLDN-KVLLSFG 263
Cdd:PRK06108 282 DFVAELVARLRRSRDHLVDALRALP------------GVEVAK--PDGAMyaffripgvTDSLALAKRLVDEaGLGLAPG 347

                        250       260       270
                 ....*....|....*....|....*....|....
gi 578820869 264 KAFECKEPGWFRFVFSDQVHRLCLGMQRVQQVLA 297
Cdd:PRK06108 348 TAFGPGGEGFLRWCFARDPARLDEAVERLRRFLA 381
PRK08363 PRK08363
alanine aminotransferase; Validated
 65-294 2.19e-11

alanine aminotransferase; Validated


Pssm-ID: 181402  Cd Length: 398  Bit Score: 64.06  E-value: 2.19e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  65 KVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFE-KSVGYRSVLSlerlPDPqrTHVMWATSKDF 143
Cdd:PRK08363 166 KTKAIAVINPNNPTGALYEKKTLKEILDIAGEHDLPVISDEIYDLMTYEgKHVSPGSLTK----DVP--VIVMNGLSKVY 239

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 144 GMSGLRFGTLYTEN-----QDVATAVASLCRYHGLSGL-VQYQMAQLLRDrdwiNQVYLPENHARLKAAHTYVSEELRAl 217
Cdd:PRK08363 240 FATGWRLGYIYFVDpegklAEVREAIDKLARIRLCPNTpAQFAAIAGLTG----PMDYLEEYMKKLKERRDYIYKRLNE- 314

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 218 gIPFLS----RGAgFFIW--VDLRKYLPKGTFEEEMLlwrrfLDNKVLLSFGKAFECKEPGWFRFVFSDQVHRLCLGMQR 291
Cdd:PRK08363 315 -IPGISttkpQGA-FYIFprIEEGPWKDDKEFVLDVL-----HEAHVLFVHGSGFGEYGAGHFRLVFLPPVEILEEAMDR 387


                 ...
gi 578820869 292 VQQ 294
Cdd:PRK08363 388 FEE 390
PLN02368 PLN02368
alanine transaminase
 22-113 3.96e-11

alanine transaminase


Pssm-ID: 177996 [Multi-domain]  Cd Length: 407  Bit Score: 63.28  E-value: 3.96e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  22 LYGNIRLAYvYLDsevtglDTRPFQLTVEKLEMALREAHSEGVKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHV 101
Cdd:PLN02368 174 LLGGTLVPY-YLE------ESENWGLDVNNLRQSVAQARSKGITVRAMVIINPGNPTGQCLSEANLREILKFCYQERLVL 246

                         90
                 ....*....|..
gi 578820869 102 IVDEVYMLSVFE 113
Cdd:PLN02368 247 LGDEVYQQNIYQ 258
PTZ00377 PTZ00377
alanine aminotransferase; Provisional
 47-159 2.42e-10

alanine aminotransferase; Provisional


Pssm-ID: 240391 [Multi-domain]  Cd Length: 481  Bit Score: 61.13  E-value: 2.42e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  47 LTVEKLEMALREAHSEGVKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFE---KSVGYRSVLS 123
Cdd:PTZ00377 200 LDQEELEEAYEQAVRNGITPRALVVINPGNPTGQVLTRDVMEEIIKFCYEKGIVLMADEVYQENIYDgekPFISFRKVLL 279

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 578820869 124 leRLPDPQRTHVMWA----TSKDF-GMSGLRFGTLYTENQD 159
Cdd:PTZ00377 280 --ELPAEYNTDVELVsfhsTSKGIiGECGRRGGYFELTNIP 318
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
 25-297 6.37e-10

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 59.84  E-value: 6.37e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  25 NIRLAYVYLDSEvtGLDtrpfqltVEKLEMALREahsEGVKvkgLILISP--QNPLGDVYSPEELQEYLVFAKRHRLHVI 102
Cdd:COG1167  215 GLRLVPVPVDED--GLD-------LDALEAALRR---HRPR---AVYVTPshQNPTGATMSLERRRALLELARRHGVPII 279

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 103 VDEVYmlsvFEKSVGYRSVLSLERLPDPQRthVMWAT--SKDFgMSGLRFGTLYTeNQDVATAVASLCRYHGL--SGLVQ 178
Cdd:COG1167  280 EDDYD----SELRYDGRPPPPLAALDAPGR--VIYIGsfSKTL-APGLRLGYLVA-PGRLIERLARLKRATDLgtSPLTQ 351

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 179 YQMAQLLRDRDWinqvylpENHAR-----LKAAHTYVSEELRAL---GIPFLSRGAGFFIWVDlrkyLPKGTFEEEmlLW 250
Cdd:COG1167  352 LALAEFLESGHY-------DRHLRrlrreYRARRDLLLAALARHlpdGLRVTGPPGGLHLWLE----LPEGVDAEA--LA 418

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 578820869 251 RRFLDNKVLLSFGKAF--ECKEPGWFRFVFSD-QVHRLCLGMQRVQQVLA 297
Cdd:COG1167  419 AAALARGILVAPGSAFsaDGPPRNGLRLGFGApSEEELEEALRRLAELLR 468
PRK06225 PRK06225
pyridoxal phosphate-dependent aminotransferase;
45-166 1.37e-09

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235749 [Multi-domain]  Cd Length: 380  Bit Score: 58.61  E-value: 1.37e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  45 FQLTVEklemALREAHSEGVKVkgLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYmlsvfeKSVGYRSVLSL 124
Cdd:PRK06225 143 YKLTPE----LVKENMDENTRL--IYLIDPLNPLGSSYTEEEIKEFAEIARDNDAFLLHDCTY------RDFAREHTLAA 210

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 578820869 125 ERlpDPQRTHVMWATSKDFGMSGLRFGTLYTEnQDVATAVAS 166
Cdd:PRK06225 211 EY--APEHTVTSYSFSKIFGMAGLRIGAVVAT-PDLIEVVKS 249
PRK13355 PRK13355
bifunctional HTH-domain containing protein/aminotransferase; Provisional
 65-301 1.82e-09

bifunctional HTH-domain containing protein/aminotransferase; Provisional


Pssm-ID: 237361 [Multi-domain]  Cd Length: 517  Bit Score: 58.59  E-value: 1.82e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  65 KVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEkSVGYRSVLSLErlPDpqrthVMWAT----S 140
Cdd:PRK13355 281 RTKAIVIINPNNPTGALYPREVLQQIVDIAREHQLIIFSDEIYDRLVMD-GLEHTSIASLA--PD-----LFCVTfsglS 352

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 141 KDFGMSGLRFGTL-YTENQDVAT---------AVASLCRYHGLSGLVQYQMA--QLLRDrdwinqvYLPENhARLKAAHT 208
Cdd:PRK13355 353 KSHMIAGYRIGWMiLSGNKRIAKdyieglnmlANMRLCSNVPAQSIVQTALGghQSVKD-------YLVPG-GRVYEQRE 424

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 209 YVSEELRAL-GIPFLSRGAGFFIW--VDLRKYlPKGTFEEEMLlwRRFLDNKVLLSFGKAFECKEPGWFRFVFSDQVHRL 285
Cdd:PRK13355 425 LVYNALNAIpGISAVKPKAAFYIFpkIDVKKF-NIHDDEQFAL--DLLHDKKVLIVQGTGFNWDKPDHFRVVYLPRLEDL 501

                        250
                 ....*....|....*.
gi 578820869 286 CLGMQRVQQVLAGKSQ 301
Cdd:PRK13355 502 EDAMDRLADFFSYYRQ 517
PLN02231 PLN02231
alanine transaminase
 20-112 7.22e-09

alanine transaminase


Pssm-ID: 177876 [Multi-domain]  Cd Length: 534  Bit Score: 56.87  E-value: 7.22e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  20 VCLYGNIRLAYvYLDsEVTGldtrpFQLTVEKLEMALREAHSEGVKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRL 99
Cdd:PLN02231 233 IALHGGTLVPY-YLD-EATG-----WGLEISELKKQLEDARSKGITVRALVVINPGNPTGQVLAEENQRDIVEFCKQEGL 305

                         90
                 ....*....|...
gi 578820869 100 HVIVDEVYMLSVF 112
Cdd:PLN02231 306 VLLADEVYQENVY 318
PRK07337 PRK07337
pyridoxal phosphate-dependent aminotransferase;
38-297 1.34e-08

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180937  Cd Length: 388  Bit Score: 55.45  E-value: 1.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  38 TGLDTRpFQLTVEKLEMALREahsegvKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYM-LSVFEKSv 116
Cdd:PRK07337 143 SGPAER-FQLTAADVEAAWGE------RTRGVLLASPSNPTGTSIAPDELRRIVEAVRARGGFTIVDEIYQgLSYDAAP- 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 117 gyRSVLSLErlpdpQRTHVMWATSKDFGMSGLRFGTLYTEN----------QDVATAVASLCRYHGLSGLVQYQMAQLLR 186
Cdd:PRK07337 215 --VSALSLG-----DDVITINSFSKYFNMTGWRLGWLVVPEalvgtfeklaQNLFICASALAQHAALACFEPDTLAIYER 287

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 187 DRdwinqvylpenhARLKAAHTYVSEELRALGI--PFLSRGAgFFIWVDLRKYLPKGTFEEEMLLWRRFLDNKVLLSFGK 264
Cdd:PRK07337 288 RR------------AEFKRRRDFIVPALESLGFkvPVMPDGA-FYVYADCRGVAHPAAGDSAALTQAMLHDAGVVLVPGR 354

                        250       260       270
                 ....*....|....*....|....*....|....
gi 578820869 265 AFECKEPGWF-RFVFSDQVHRLCLGMQRVQQVLA 297
Cdd:PRK07337 355 DFGPHAPRDYiRLSYATSMSRLEEAVARLGKLFG 388
PRK03317 PRK03317
histidinol-phosphate aminotransferase; Provisional
 45-275 2.42e-08

histidinol-phosphate aminotransferase; Provisional


Pssm-ID: 235115  Cd Length: 368  Bit Score: 54.87  E-value: 2.42e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  45 FQLTVEKLEMALREaHSEGVkvkgLILISPQNPLGDVYSPEELQEYLVFAkrhRLHVIVDEVYMlsVFEKSvGYRSVLSL 124
Cdd:PRK03317 145 FTLDVDAAVAAIAE-HRPDV----VFLTSPNNPTGTALPLDDVEAILDAA---PGIVVVDEAYA--EFRRS-GTPSALTL 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 125 erLPDPQRTHVMWATSKDFGMSGLRFGTLytenqdVAT-AVASLCR-----YHgLSGLVQYQMAQLLRDRD-WINQVylp 197
Cdd:PRK03317 214 --LPEYPRLVVSRTMSKAFAFAGGRLGYL------AAApAVVDALRlvrlpYH-LSAVTQAAARAALRHADeLLASV--- 281

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578820869 198 enhARLKAAHTYVSEELRALGIPFLSRGAGFFIWvdlrkylpkGTFEEEMLLWRRFLDNKVLLSfgkafECKEPGWFR 275
Cdd:PRK03317 282 ---AALRAERDRVVAWLRELGLRVAPSDANFVLF---------GRFADRHAVWQGLLDRGVLIR-----DVGIPGWLR 342
tyr_amTase_E TIGR01264
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ...
 16-277 3.57e-08

tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]


Pssm-ID: 273529 [Multi-domain]  Cd Length: 401  Bit Score: 54.40  E-value: 3.57e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869   16 RPGhVCLYGNIRLAYvyldsevtGLDTRPFQLTVEK-LEMALREAHS-EGVKVKGLILISPQNPLGDVYSPEELQEYLVF 93
Cdd:TIGR01264 126 RPG-FPLYETLAESM--------GIEVKLYNLLPDKsWEIDLKQLESlIDEKTAALIVNNPSNPCGSVFSRQHLEEILAV 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869   94 AKRHRLHVIVDEVYMLSVFEKSVgYRSVLSLErlPDPQRThVMWATSKDFGMSGLRFGTLYTENQ-----DVATAVASLC 168
Cdd:TIGR01264 197 AERQCLPIIADEIYGDMVFSGAT-FEPLASLS--STVPIL-SCGGLAKRWLVPGWRLGWIIIHDRrgilrDIRDGLVKLS 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  169 -RYHGLSGLVQYQMAQLLRDRDwinQVYLPENHARLKAAHTYVSEELRAL-GI-PFLSRGAGF-FIWVDLRKYlpkGTFE 244
Cdd:TIGR01264 273 qRILGPCTIVQGALPSILLRTP---QEYFDGTLSVLESNAMLCYGALAAVpGLrPVMPSGAMYmMVGIEMEHF---PEFK 346

                         250       260       270
                  ....*....|....*....|....*....|....
gi 578820869  245 EEMLLWRRFL-DNKVLLSFGKAFECkePGWFRFV 277
Cdd:TIGR01264 347 NDVEFTERLVaEQSVFCLPGSCFEY--PGFFRVV 378
PRK07777 PRK07777
putative succinyldiaminopimelate transaminase DapC;
41-235 3.93e-08

putative succinyldiaminopimelate transaminase DapC;


Pssm-ID: 236095 [Multi-domain]  Cd Length: 387  Bit Score: 54.27  E-value: 3.93e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  41 DTRPFQLTVEKLEMALreahseGVKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKsvgyRS 120
Cdd:PRK07777 141 DGRGFALDLDALRAAV------TPRTRALIVNSPHNPTGTVLTAAELAAIAELAVEHDLLVITDEVYEHLVFDG----AR 210

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 121 VLSLERLPD-PQRTHVMWATSKDFGMSGLRFGTLyTENQDVATAVASLCRYhgLS----GLVQYQMAQLLRDRDwinqVY 195
Cdd:PRK07777 211 HLPLATLPGmRERTVTISSAAKTFNVTGWKIGWA-CGPAPLIAAVRAAKQY--LTyvggAPFQPAVAHALDHED----AW 283

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 578820869 196 LPENHARLKAAHTYVSEELRALGIPFLSRGAGFFIWVDLR 235
Cdd:PRK07777 284 VAALRDSLQAKRDRLAAGLAEAGFEVHDSAGTYFLCADPR 323
PRK08912 PRK08912
aminotransferase;
53-235 5.64e-08

aminotransferase;


Pssm-ID: 181580  Cd Length: 387  Bit Score: 53.44  E-value: 5.64e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  53 EMALREAHSEgvKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEkSVGYRSVLSLERLPDpqR 132
Cdd:PRK08912 149 RAALAAAFSP--RTKAVLLNNPLNPAGKVFPREELALLAEFCQRHDAVAICDEVWEHVVFD-GRRHIPLMTLPGMRE--R 223

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 133 THVMWATSKDFGMSGLRFGTL------------------YTENQDVATAVAslcryHGLSGLVQY--QM-AQLLRDRDwi 191
Cdd:PRK08912 224 TVKIGSAGKIFSLTGWKVGFVcaappllrvlakahqfltFTTPPNLQAAVA-----YGLGKPDDYfeGMrADLARSRD-- 296

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 578820869 192 nqvylpenhaRLkaahtyvSEELRALGIPFLSRGAGFFIWVDLR 235
Cdd:PRK08912 297 ----------RL-------AAGLRRIGFPVLPSQGTYFLTVDLA 323
PRK06107 PRK06107
aspartate transaminase;
45-151 6.89e-08

aspartate transaminase;


Pssm-ID: 180403  Cd Length: 402  Bit Score: 53.59  E-value: 6.89e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  45 FQLTVEKLEMALREahsegvKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHR-LHVIVDEVYMLSVFEKSVGYRSVLS 123
Cdd:PRK06107 152 FKLTPEALEAAITP------RTRWLILNAPSNPTGAVYSRAELRALADVLLRHPhVLVLTDDIYDHIRFDDEPTPHLLAA 225

                         90       100
                 ....*....|....*....|....*...
gi 578820869 124 LERLPDpqRTHVMWATSKDFGMSGLRFG 151
Cdd:PRK06107 226 APELRD--RVLVTNGVSKTYAMTGWRIG 251
PRK06836 PRK06836
pyridoxal phosphate-dependent aminotransferase;
41-305 8.57e-08

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180720  Cd Length: 394  Bit Score: 52.89  E-value: 8.57e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  41 DTRPFQLTVEKLEMALREahsegvKVKGLILISPQNPLGDVYSPEELQEY--LVFAKR----HRLHVIVDEVYMLSVFE- 113
Cdd:PRK06836 150 DTDTFQPDLDALEAAITP------KTKAVIINSPNNPTGVVYSEETLKALaaLLEEKSkeygRPIYLISDEPYREIVYDg 223

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 114 KSVGYrsVLSLERlpdpqRTHVMWATSKDFGMSGLRFGTLYT--ENQDVATAVASLC---RYHGL---SGLVQYQMAQLL 185
Cdd:PRK06836 224 AEVPY--IFKYYD-----NSIVVYSFSKSLSLPGERIGYIAVnpEMEDADDLVAALVfanRILGFvnaPALMQRVVAKCL 296

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 186 RDRDWINqVYLpENHARLkaahtYvsEELRALGIPFLSRGAGFFIWvdlrkylPKGTFEEEMLLWRRFLDNKVLLSFGKA 265
Cdd:PRK06836 297 DATVDVS-IYK-RNRDLL-----Y--DGLTELGFECVKPQGAFYLF-------PKSPEEDDVAFCEKAKKHNLLLVPGSG 360

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 578820869 266 FECkePGWFRFVFsdqvhrlCLGMQRVQQVLAGKSQVAED 305
Cdd:PRK06836 361 FGC--PGYFRLSY-------CVDTETIERSLPAFEKLAKE 391
tyr_nico_aTase TIGR01265
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ...
 16-112 1.28e-07

tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.


Pssm-ID: 188123  Cd Length: 403  Bit Score: 52.73  E-value: 1.28e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869   16 RPGHvCLYgNIRLAYvyldsevTGLDTRPFQLTVEK--------LEMALREahsegvKVKGLILISPQNPLGDVYSPEEL 87
Cdd:TIGR01265 127 RPGF-PLY-DTRAAF-------SGLEVRLYDLLPEKdweidldgLESLADE------KTVAIVVINPSNPCGSVFSRDHL 191

                          90       100
                  ....*....|....*....|....*
gi 578820869   88 QEYLVFAKRHRLHVIVDEVYMLSVF 112
Cdd:TIGR01265 192 QKIAEVAEKLGIPIIADEIYGHMVF 216
PRK08960 PRK08960
pyridoxal phosphate-dependent aminotransferase;
38-296 3.77e-07

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181595  Cd Length: 387  Bit Score: 51.21  E-value: 3.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  38 TGLDTRpFQLTVEKLEMALREahsegvKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEksVG 117
Cdd:PRK08960 145 VGPDSR-YQLTPALVERHWNA------DTVGALVASPANPTGTLLSRDELAALSQALRARGGHLVVDEIYHGLTYG--VD 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 118 YRSVLSLErlpdpQRTHVMWATSKDFGMSGLRFGTLYTENQDVAtAVASLCRYHGLSGLVQYQMAQLlrdrdwinQVYLP 197
Cdd:PRK08960 216 AASVLEVD-----DDAFVLNSFSKYFGMTGWRLGWLVAPPAAVP-ELEKLAQNLYISASTPAQHAAL--------ACFEP 281

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 198 ENHARLKAAHT-------YVSEELRALG--IPFLSRGAgFFIWVDLRKYLpkgtfEEEMLLWRRFLDNK-VLLSFGKAFE 267
Cdd:PRK08960 282 ETLAILEARRAefarrrdFLLPALRELGfgIAVEPQGA-FYLYADISAFG-----GDAFAFCRHFLETEhVAFTPGLDFG 355

                        250       260       270
                 ....*....|....*....|....*....|
gi 578820869 268 CKEPG-WFRFVFSDQVHRLCLGMQRVQQVL 296
Cdd:PRK08960 356 RHQAGqHVRFAYTQSLPRLQEAVERIARGL 385
PRK06207 PRK06207
pyridoxal phosphate-dependent aminotransferase;
55-154 4.82e-07

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235742  Cd Length: 405  Bit Score: 50.92  E-value: 4.82e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  55 ALREAHSEGVKVkgLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKsvgyRSVLSLERLP-DPQRT 133
Cdd:PRK06207 170 QLEEAFKAGVRV--FLFSNPNNPAGVVYSAEEIAQIAALARRYGATVIVDQLYSRLLYDG----TSYTHLRALPiDPENV 243

                         90       100
                 ....*....|....*....|.
gi 578820869 134 HVMWATSKDFGMSGLRFGTLY 154
Cdd:PRK06207 244 ITIMGPSKTESLSGYRLGVAF 264
PRK09265 PRK09265
aminotransferase AlaT; Validated
 65-107 1.14e-06

aminotransferase AlaT; Validated


Pssm-ID: 181738  Cd Length: 404  Bit Score: 49.81  E-value: 1.14e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 578820869  65 KVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVY 107
Cdd:PRK09265 168 RTKAIVIINPNNPTGAVYSKELLEEIVEIARQHNLIIFADEIY 210
PRK07550 PRK07550
aminotransferase;
65-107 1.49e-06

aminotransferase;


Pssm-ID: 181026 [Multi-domain]  Cd Length: 386  Bit Score: 49.19  E-value: 1.49e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 578820869  65 KVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVY 107
Cdd:PRK07550 163 RTRAIALVTPNNPTGVVYPPELLHELYDLARRHGIALILDETY 205
PRK07324 PRK07324
transaminase; Validated
 69-297 4.82e-06

transaminase; Validated


Pssm-ID: 235989  Cd Length: 373  Bit Score: 47.62  E-value: 4.82e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  69 LILIS-PQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYM-----------LSVFEKSVgyrSVLSLerlpdpqrthvm 136
Cdd:PRK07324 156 LICINnANNPTGALMDRAYLEEIVEIARSVDAYVLSDEVYRpldedgstpsiADLYEKGI---STNSM------------ 220

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 137 watSKDFGMSGLRFGTLYTeNQDVATAVASLCRYHGLS-GLVQYQMAQL-LRDRDWI---NQVYLPENHARLKAahtYVS 211
Cdd:PRK07324 221 ---SKTYSLPGIRVGWIAA-NEEVIDILRKYRDYTMICaGVFDDMLASLaLEHRDAIlerNRKIVRTNLAILDE---WVA 293

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 212 EELRALGI-PflSRGAGFFIWVDLRkyLPKGTFEEEMLlwrrfLDNKVLLSFGKAFEckEPGWFRFVFSDQVHRLCLGMQ 290
Cdd:PRK07324 294 KEPRVSYVkP--KAVSTSFVKLDVD--MPSEDFCLKLL-----KETGVLLVPGNRFD--LEGHVRIGYCCDTETLKKGLK 362


                 ....*..
gi 578820869 291 RVQQVLA 297
Cdd:PRK07324 363 KLSEFLR 369
PRK05957 PRK05957
pyridoxal phosphate-dependent aminotransferase;
45-151 1.08e-05

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235654  Cd Length: 389  Bit Score: 46.60  E-value: 1.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  45 FQLTVEKLEMALREahsegvKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEksvGYRSVlSL 124
Cdd:PRK05957 146 YQLQPEAIEQAITP------KTRAIVTISPNNPTGVVYPEALLRAVNQICAEHGIYHISDEAYEYFTYD---GVKHF-SP 215

                         90       100
                 ....*....|....*....|....*...
gi 578820869 125 ERLPDPQR-THVMWATSKDFGMSGLRFG 151
Cdd:PRK05957 216 GSIPGSGNhTISLYSLSKAYGFASWRIG 243
PLN02187 PLN02187
rooty/superroot1
 4-112 1.41e-05

rooty/superroot1


Pssm-ID: 215119 [Multi-domain]  Cd Length: 462  Bit Score: 46.26  E-value: 1.41e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869   4 PRSSLLWPRccvrPGHVclYGNIRLAYvyldsevTGLDTRPFQLTVEK---LEMALREAHSEGVKVkGLILISPQNPLGD 80
Cdd:PLN02187 154 PNANILLPR----PGFP--HYDARAAY-------SGLEVRKFDLLPEKeweIDLEGIEAIADENTV-AMVVINPNNPCGN 219

                         90       100       110
                 ....*....|....*....|....*....|..
gi 578820869  81 VYSPEELQEYLVFAKRHRLHVIVDEVYMLSVF 112
Cdd:PLN02187 220 VYSHDHLKKVAETARKLGIMVISDEVYDRTIF 251
PRK06855 PRK06855
pyridoxal phosphate-dependent aminotransferase;
49-107 2.25e-05

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180734  Cd Length: 433  Bit Score: 45.71  E-value: 2.25e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 578820869  49 VEKLEMALREAHSegvkVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVY 107
Cdd:PRK06855 159 LDDLENKVKYNPS----IAGILLINPDNPTGAVYPKEILREIVDIAREYDLFIICDEIY 213
PRK07681 PRK07681
LL-diaminopimelate aminotransferase;
65-241 2.31e-05

LL-diaminopimelate aminotransferase;


Pssm-ID: 181081  Cd Length: 399  Bit Score: 45.57  E-value: 2.31e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  65 KVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKsvgyRSVLSLERLPDPQRTHV-MWATSKDF 143
Cdd:PRK07681 166 KAKMMILNFPGNPVPAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEFYFDG----NKPISFLSVPGAKEVGVeINSLSKSY 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 144 GMSGLRFGTLyTENQDVATAVASLCRY--HGLSGLVQYQMAQLLRDRDwinqVYLPENHARLKAAHTYVSEELRALGIPF 221
Cdd:PRK07681 242 SLAGSRIGYM-IGNEEIVRALTQFKSNtdYGVFLPIQKAACAALRNGA----AFCEKNRGIYQERRDTLVDGFRTFGWNV 316

                        170       180
                 ....*....|....*....|
gi 578820869 222 LSRGAGFFIWVDlrkyLPKG 241
Cdd:PRK07681 317 DKPAGSMFVWAE----IPKG 332
PLN00175 PLN00175
aminotransferase family protein; Provisional
 35-151 4.84e-05

aminotransferase family protein; Provisional


Pssm-ID: 215089 [Multi-domain]  Cd Length: 413  Bit Score: 44.47  E-value: 4.84e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  35 SEVTGLDTRP--FQLTVEKLEMALREahsegvKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVF 112
Cdd:PLN00175 161 AKIKTVTLRPpdFAVPEDELKAAFTS------KTRAILINTPHNPTGKMFTREELELIASLCKENDVLAFTDEVYDKLAF 234

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 578820869 113 EKsvgyrSVLSLERLPDP-QRTHVMWATSKDFGMSGLRFG 151
Cdd:PLN00175 235 EG-----DHISMASLPGMyERTVTMNSLGKTFSLTGWKIG 269
PLN02656 PLN02656
tyrosine transaminase
 4-107 7.46e-05

tyrosine transaminase


Pssm-ID: 178262 [Multi-domain]  Cd Length: 409  Bit Score: 44.14  E-value: 7.46e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869   4 PRSSLLWPRCCVRPGHVClygnirlayvyldSEVTGLDTRPFQLTVEK---LEMALREAHSEGVKVkGLILISPQNPLGD 80
Cdd:PLN02656 119 PGANILLPRPGFPIYELC-------------AAFRHLEVRYVDLLPEKgweVDLDAVEALADQNTV-ALVIINPGNPCGN 184

                         90       100
                 ....*....|....*....|....*..
gi 578820869  81 VYSPEELQEYLVFAKRHRLHVIVDEVY 107
Cdd:PLN02656 185 VYSYQHLKKIAETAEKLKILVIADEVY 211
PTZ00433 PTZ00433
tyrosine aminotransferase; Provisional
 39-151 8.85e-05

tyrosine aminotransferase; Provisional


Pssm-ID: 185613  Cd Length: 412  Bit Score: 43.62  E-value: 8.85e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  39 GLDTRPFQLTVEK-LEMALREAHS--EGvKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKS 115
Cdd:PTZ00433 149 GIEMRFYNCRPEKdWEADLDEIRRlvDD-RTKALIMTNPSNPCGSNFSRKHVEDIIRLCEELRLPLISDEIYAGMVFNGA 227

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 578820869 116 VgYRSVLSLERlPDPQrtHVMWATSKDFGMSGLRFG 151
Cdd:PTZ00433 228 T-FTSVADFDT-TVPR--VILGGTAKNLVVPGWRLG 259
PRK07366 PRK07366
LL-diaminopimelate aminotransferase;
65-151 3.12e-04

LL-diaminopimelate aminotransferase;


Pssm-ID: 180947  Cd Length: 388  Bit Score: 41.97  E-value: 3.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  65 KVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKSVGYRSVLslerLPDPQRTHVM--WATSKD 142
Cdd:PRK07366 165 QARLMVLSYPHNPTTAIAPLSFFQEAVAFCQQHDLVLVHDFPYVDLVFDGEVEPPSIL----QADPEKSVSIefFTLSKS 240


                 ....*....
gi 578820869 143 FGMSGLRFG 151
Cdd:PRK07366 241 YNMGGFRIG 249
PLN00143 PLN00143
tyrosine/nicotianamine aminotransferase; Provisional
 4-293 3.27e-04

tyrosine/nicotianamine aminotransferase; Provisional


Pssm-ID: 165711 [Multi-domain]  Cd Length: 409  Bit Score: 41.92  E-value: 3.27e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869   4 PRSSLLWPRccvrPGHvclygniRLAYVYLDSEvtGLDTRPFQLTVEK---LEMALREAHSEGVKVkGLILISPQNPLGD 80
Cdd:PLN00143 120 PEANILLPR----PGF-------PDVETYAIFH--HLEIRHFDLLPEKgweVDLDAVEAIADENTI-AMVIINPGNPCGS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  81 VYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFeksvGYRSVLSLERLPDPQRTHVMWATSKDFGMSGLRFGTLYTENQ-- 158
Cdd:PLN00143 186 VYSYEHLNKIAETARKLGILVIADEVYGHIVF----GSKPFVPMGLFASIVPVITLGSISKRWMIPGWGLGWLVTCDPsg 261

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 159 -----DVATAVASLCRYHGLS-GLVQYQMAQLLRDrdwINQVYLPENHARLKAAHTYVSEELR---ALGIPFLSRGAgFF 229
Cdd:PLN00143 262 llqicEIADSIKKALNPAPFPpTFIQAAIPEILEK---TTEDFFSKTINILRAALAFCYDKLKeipCIMCPQKAEGA-FF 337

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578820869 230 IWVDLRKYLPKgTFEEEMLLWRRFLDNKVLLSF-GKAFECKEpgWFRFVFSDQVHRLCLGMQRVQ 293
Cdd:PLN00143 338 ALVKLNLLLLE-DIEDDMEFCLKLAKEESLIILpGVTVGLKN--WLRITFAVEQSSLEDGLGRLK 399
PRK08361 PRK08361
aspartate aminotransferase; Provisional
 65-298 4.14e-04

aspartate aminotransferase; Provisional


Pssm-ID: 236248 [Multi-domain]  Cd Length: 391  Bit Score: 41.79  E-value: 4.14e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  65 KVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEksvGYRSVLSLERLPDpqRTHVMWATSKDFG 144
Cdd:PRK08361 166 RTRMIVINYPNNPTGATLDKEVAKAIADIAEDYNIYILSDEPYEHFLYE---GAKHYPMIKYAPD--NTILANSFSKTFA 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 145 MSGLRFGTLYTENQdvatAVASLCRYHG-----LSGLVQYQMAQLLRD-RDW-----INQVYlpenHARLKAAHTYVSEe 213
Cdd:PRK08361 241 MTGWRLGFVIAPEQ----VIKDMIKLHAyiignVASFVQIAGIEALRSkESWkaveeMRKEY----NERRKLVLKRLKE- 311

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 214 lrALGI-PFLSRGAgFFIWVDLRKylpKGTFEEEMLLWrrFLDN-KVLLSFGKAFECKEPGWFRFVFSDQVHRLCLGMQR 291
Cdd:PRK08361 312 --MPHIkVFEPKGA-FYVFANIDE---TGMSSEDFAEW--LLEKaRVVVIPGTAFGKAGEGYIRISYATSKEKLIEAMER 383


                 ....*..
gi 578820869 292 VQQVLAG 298
Cdd:PRK08361 384 MEKALEE 390
PRK05166 PRK05166
histidinol-phosphate transaminase;
49-248 6.26e-04

histidinol-phosphate transaminase;


Pssm-ID: 179950  Cd Length: 371  Bit Score: 40.89  E-value: 6.26e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  49 VEKLEM---------ALREAHSEGVKVkgLILISPQNPLGDVYSPEELQEyLVFAKRHRLHVIVDEVYmlSVFEKSVGYR 119
Cdd:PRK05166 136 VERVTVtpdlgfdldALCAAVARAPRM--LMFSNPSNPVGSWLTADQLAR-VLDATPPETLIVVDEAY--AEYAAGDDYP 210

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 120 SVLSLerLPDPQRTHVMWAT-SKDFGMSGLRFGtlYTENQDvatavASLCryhGLSGLVQY-----QMAQLLRDRDWINQ 193
Cdd:PRK05166 211 SALTL--LKARGLPWIVLRTfSKAYGLAGLRVG--YGLVSD-----PELV---GLLDRVRTpfnvnGAAQAAALAALDDE 278

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 578820869 194 VYLPENHARLKAAHTYVSEELRALGIpFLSRGAGFFIWVDLRKylPKGTFEEEML 248
Cdd:PRK05166 279 EHLAKGVALALAERERLKKELAEMGY-RIAPSRANFLFFDARR--PASAVAEALL 330
PRK09105 PRK09105
pyridoxal phosphate-dependent aminotransferase;
56-248 2.49e-03

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181651  Cd Length: 370  Bit Score: 39.26  E-value: 2.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  56 LREAHSEGVKV-------KGLILI-SPQNPLGDVYSPEELqEYLVFAKRHRLHVIVDEVY-----MLSVFEKSVGYRSVL 122
Cdd:PRK09105 148 LRADGAHDVKAmlaadpnAGLIYIcNPNNPTGTVTPRADI-EWLLANKPAGSVLLVDEAYihfsdAPSVVDLVAQRKDLI 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869 123 SLerlpdpqRTHvmwatSKDFGMSGLRFG------------TLYTENQDVATAVAslcryhglSGLVQYQMAQLlrdrdw 190
Cdd:PRK09105 227 VL-------RTF-----SKLYGMAGMRLGlaaarpdllaklARFGHNPLPVPAAA--------AGLASLRDPKL------ 280

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 578820869 191 inqvyLPENHARLKAAHTYVSEELRALGIPFLSRGAGFFIwVDLRKylPKGTFEEEML 248
Cdd:PRK09105 281 -----VPQRRAENAAVREDTIAWLKKKGYKCTPSQANCFM-VDVKR--PAKAVADAMA 330
PLN00145 PLN00145
tyrosine/nicotianamine aminotransferase; Provisional
 39-112 5.11e-03

tyrosine/nicotianamine aminotransferase; Provisional


Pssm-ID: 215074 [Multi-domain]  Cd Length: 430  Bit Score: 38.21  E-value: 5.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578820869  39 GLDTRPFQLTVEKLemalREAHSEGVK------VKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVF 112
Cdd:PLN00145 162 GLEVRHFDLLPERG----WEVDLEGVEaladenTVAMVIINPNNPCGSVYSYEHLAKIAETARKLGILVIADEVYDHLTF 237
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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