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Conserved domains on  [gi|767950100|ref|XP_006716297|]
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glutamate-rich protein 1 isoform X2 [Homo sapiens]

Protein Classification

ICP22 family protein( domain architecture ID 708738)

ICP22 family protein similar to Herpesvirus saimiri transcriptional regulator ICP22 homolog (also known as immediate-early protein) that regulates the transcription of alphaherpesviruses and their host genes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03169 super family cl27451
hypothetical protein; Provisional
 191-335 7.79e-06

hypothetical protein; Provisional


The actual alignment was detected with superfamily member PHA03169:

Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 48.43  E-value: 7.79e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100 191 QPEDSSNEGEGVGEACEEDGVDTSEEDptlAGEEDVKDTREEDGADASEEdltrARQEEGADASEEDPTPAGEEDVKDAR 270
Cdd:PHA03169  47 APPAPTTSGPQVRAVAEQGHRQTESDT---ETAEESRHGEKEERGQGGPS----GSGSESVGSPTPSPSGSAEELASGLS 119

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767950100 271 EEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITNE 335
Cdd:PHA03169 120 PENTSGSSPESPASHSPPPSPPSHPGPHEPAPPESHNPSPNQQPSSFLQPSHEDSPEEPEPPTSE 184
 
Name Accession Description Interval E-value
PHA03169 PHA03169
hypothetical protein; Provisional
 191-335 7.79e-06

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 48.43  E-value: 7.79e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100 191 QPEDSSNEGEGVGEACEEDGVDTSEEDptlAGEEDVKDTREEDGADASEEdltrARQEEGADASEEDPTPAGEEDVKDAR 270
Cdd:PHA03169  47 APPAPTTSGPQVRAVAEQGHRQTESDT---ETAEESRHGEKEERGQGGPS----GSGSESVGSPTPSPSGSAEELASGLS 119

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767950100 271 EEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITNE 335
Cdd:PHA03169 120 PENTSGSSPESPASHSPPPSPPSHPGPHEPAPPESHNPSPNQQPSSFLQPSHEDSPEEPEPPTSE 184
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 132-330 5.69e-05

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 46.14  E-value: 5.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100   132 EQAELEKQQSLLQEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEAcEEDGV 211
Cdd:TIGR00927  661 EESGGEAEQEGETETKGENESEGEIPAERKGEQEGEGEIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEIET-GEEGE 739

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100   212 DTSEEDPTLA---GEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDL------ 282
Cdd:TIGR00927  740 EVEDEGEGEAegkHEVETEGDRKETEHEGETEAEGKEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDehegqs 819

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 767950100   283 -TRAGEEDGKDTREEDGADASEEDPTWAGEE--------EGADSGEEDGADASEEDD 330
Cdd:TIGR00927  820 eTQADDTEVKDETGEQELNAENQGEAKQDEKgvdggggsDGGDSEEEEEEEEEEEEE 876
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 251-331 2.31e-04

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 44.01  E-value: 2.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100 251 ADASEEDPTPAGEEDVKDAREEDGvdtiEEDLTRAGEEDGKDTREEDGADASEEDPTwAGEEEGADSGEEDGADASEEDD 330
Cdd:COG4547  208 AEELGEDEDEEDEDDEDDSGEQEE----DEEDGEDEDEESDEGAEAEDAEASGDDAE-EGESEAAEAESDEMAEEAEGED 282


                 .
gi 767950100 331 T 331
Cdd:COG4547  283 S 283
TFIIF_alpha pfam05793
Transcription initiation factor IIF, alpha subunit (TFIIF-alpha); Transcription initiation ...
 193-336 3.21e-03

Transcription initiation factor IIF, alpha subunit (TFIIF-alpha); Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) or RNA polymerase II-associating protein 74 (RAP74) is the large subunit of transcription factor IIF (TFIIF), which is essential for accurate initiation and stimulates elongation by RNA polymerase II.


Pssm-ID: 310411 [Multi-domain]  Cd Length: 528  Bit Score: 40.32  E-value: 3.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100  193 EDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDltRARQEEGADASEEDPTPAGEEDVKDAREE 272
Cdd:pfam05793 197 EETEGEKGGGGRGKDLKIKDLEGDDEDDGDESDKGGEDGDEEKKKKKKK--KLAKNKKKLDDDKKKKRGGDDDAFEYDSD 274

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767950100  273 DGVD-TIEEDLTRAGEEDGKDTREEDGADASEEDPtwAGEEEGADSGEEDGADASEEDDTITNEK 336
Cdd:pfam05793 275 DGDDeGREEDYISDSSASGNDPEEREDKLSPEEPA--KGEIEQSDDSEESEEEKNEEEGKLSKKG 337
 
Name Accession Description Interval E-value
PHA03169 PHA03169
hypothetical protein; Provisional
 191-335 7.79e-06

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 48.43  E-value: 7.79e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100 191 QPEDSSNEGEGVGEACEEDGVDTSEEDptlAGEEDVKDTREEDGADASEEdltrARQEEGADASEEDPTPAGEEDVKDAR 270
Cdd:PHA03169  47 APPAPTTSGPQVRAVAEQGHRQTESDT---ETAEESRHGEKEERGQGGPS----GSGSESVGSPTPSPSGSAEELASGLS 119

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767950100 271 EEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITNE 335
Cdd:PHA03169 120 PENTSGSSPESPASHSPPPSPPSHPGPHEPAPPESHNPSPNQQPSSFLQPSHEDSPEEPEPPTSE 184
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 197-336 3.22e-05

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 47.09  E-value: 3.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100  197 NEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVD 276
Cdd:PTZ00341  930 NQNENVPEHLKEHAEANIEEDAEENVEEDAEENVEENVEENVEENVEENVEENVEENVEENVEENVEENVEENIEENVEE 1009

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767950100  277 TIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGE-EEGADSG-EEDGADASEEDDTITNEK 336
Cdd:PTZ00341 1010 NVEENIEENVEEYDEENVEEVEENVEEYDEENVEEiEENAEENvEENIEENIEEYDEENVEE 1071
PHA03169 PHA03169
hypothetical protein; Provisional
 192-337 5.31e-05

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 45.73  E-value: 5.31e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100 192 PEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDltraRQEEGADASEEDPTPAGEEDVKDARE 271
Cdd:PHA03169 105 PSPSGSAEELASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAPPES----HNPSPNQQPSSFLQPSHEDSPEEPEP 180

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767950100 272 EDGVDtiEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGeeDGADASEEDDTITNEKA 337
Cdd:PHA03169 181 PTSEP--EPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPTPQQAPSP--NTQQAVEHEDEPTEPER 242
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 132-330 5.69e-05

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 46.14  E-value: 5.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100   132 EQAELEKQQSLLQEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEAcEEDGV 211
Cdd:TIGR00927  661 EESGGEAEQEGETETKGENESEGEIPAERKGEQEGEGEIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEIET-GEEGE 739

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100   212 DTSEEDPTLA---GEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDL------ 282
Cdd:TIGR00927  740 EVEDEGEGEAegkHEVETEGDRKETEHEGETEAEGKEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDehegqs 819

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 767950100   283 -TRAGEEDGKDTREEDGADASEEDPTWAGEE--------EGADSGEEDGADASEEDD 330
Cdd:TIGR00927  820 eTQADDTEVKDETGEQELNAENQGEAKQDEKgvdggggsDGGDSEEEEEEEEEEEEE 876
PHA03169 PHA03169
hypothetical protein; Provisional
 194-330 1.01e-04

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 44.96  E-value: 1.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100 194 DSSNEGEGVGEACEEDGVDtSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREED 273
Cdd:PHA03169  89 QGGPSGSGSESVGSPTPSP-SGSAEELASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAPPESHNPSPNQQPSSFL 167

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767950100 274 GVDTIEEDltraGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDD 330
Cdd:PHA03169 168 QPSHEDSP----EEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPTPQ 220
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 209-349 1.31e-04

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 45.16  E-value: 1.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100  209 DGVDTSEEdptlageEDVKDTREEDGADASEEDLTRAR--QEEGADASEE---DPTPAGEEDVKDAREEDGVDTIEEDLT 283
Cdd:PTZ00341  426 DMLDGSED-------ESVEDNEEEHSGDANEEELSVDEhvEEHNADDSGEqqsDDESGEHQSVNEIVEEQSVNEHVEEPT 498

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767950100  284 RAgeedgkDTREEDGADASEEDPT--WAGEEEGADSG-EEDGADAS--EEDDTITNEKAHSILNFLKSTQE 349
Cdd:PTZ00341  499 VA------DIVEQETVDEHVEEPAvdENEEQQTADEHvEEPTIAEEhvEEEISTAEEHIEEPASDVQQDSE 563
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 251-331 2.31e-04

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 44.01  E-value: 2.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100 251 ADASEEDPTPAGEEDVKDAREEDGvdtiEEDLTRAGEEDGKDTREEDGADASEEDPTwAGEEEGADSGEEDGADASEEDD 330
Cdd:COG4547  208 AEELGEDEDEEDEDDEDDSGEQEE----DEEDGEDEDEESDEGAEAEDAEASGDDAE-EGESEAAEAESDEMAEEAEGED 282


                 .
gi 767950100 331 T 331
Cdd:COG4547  283 S 283
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 204-312 2.97e-04

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 44.01  E-value: 2.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100  204 EACEEDGVDTSEEDPTLAGEEDVKDTRE--EDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGV---DTI 278
Cdd:PTZ00341 1020 EEYDEENVEEVEENVEEYDEENVEEIEEnaEENVEENIEENIEEYDEENVEEIEENIEENIEENVEENVEENVEeieENV 1099

                          90       100       110
                  ....*....|....*....|....*....|....
gi 767950100  279 EEDLTRAGEEDGKDTREEDGADASEEDPTWAGEE 312
Cdd:PTZ00341 1100 EENVEENAEENAEENAEENAEEYDDENPEEHNEE 1133
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 207-316 3.07e-04

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 43.63  E-value: 3.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100 207 EEDGVDTSEEDPtlaGEEDVKDTREEDGADASEEDltrarQEEGADASEEDPTPAGEEDvkDAREEDGVDTIEEDLtrag 286
Cdd:COG4547  209 EELGEDEDEEDE---DDEDDSGEQEEDEEDGEDED-----EESDEGAEAEDAEASGDDA--EEGESEAAEAESDEM---- 274

                         90       100       110
                 ....*....|....*....|....*....|
gi 767950100 287 EEDGKDTREEDGADASEEDPTWAGEEEGAD 316
Cdd:COG4547  275 AEEAEGEDSEEPGEPWRPNAPPPDDPADPD 304
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 193-335 3.43e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 43.83  E-value: 3.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100   193 EDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVkDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREE 272
Cdd:TIGR00927  756 ETEGDRKETEHEGETEAEGKEDEDEGEIQAGEDG-EMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGE 834

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767950100   273 DGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITNE 335
Cdd:TIGR00927  835 QELNAENQGEAKQDEKGVDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLE 897
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 192-337 6.85e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 42.68  E-value: 6.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100   192 PEDSSNEGEGVGEACEEDGVDTSEEDptlAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDARE 271
Cdd:TIGR00927  686 PAERKGEQEGEGEIEAKEADHKGETE---AEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRK 762

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767950100   272 EDGVDTIEEDLTRAGEEDGKDTREEDGADASEEdptwaGEEEGADSGEEDGADASEEDDTITNEKA 337
Cdd:TIGR00927  763 ETEHEGETEAEGKEDEDEGEIQAGEDGEMKGDE-----GAEGKVEHEGETEAGEKDEHEGQSETQA 823
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 193-303 8.66e-04

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 42.47  E-value: 8.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100  193 EDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASE--EDLTRARQEEGADASEEDPTPAGEEDVKDAR 270
Cdd:PTZ00341 1024 EENVEEVEENVEEYDEENVEEIEENAEENVEENIEENIEEYDEENVEeiEENIEENIEENVEENVEENVEEIEENVEENV 1103

                          90       100       110
                  ....*....|....*....|....*....|...
gi 767950100  271 EEDGVDTIEEDLTRAGEEDGKDTREEDGADASE 303
Cdd:PTZ00341 1104 EENAEENAEENAEENAEEYDDENPEEHNEEYDE 1136
PRK05901 PRK05901
RNA polymerase sigma factor; Provisional
 132-345 1.32e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 235640 [Multi-domain]  Cd Length: 509  Bit Score: 41.52  E-value: 1.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100 132 EQAELEKQQSLLQEKSQRQHTDGTTISKNKKRKLKKKQQIKRKKAAGLAAKAAGVSFMYQPEDSSNEGEGVGEACEEDGV 211
Cdd:PRK05901   9 ELAAEEEAKKKLKKLAAKSKSKGFITKEEIKEALESKKKTPEQIDQVLIFLSGMVKDTDDATESDIPKKKTKTAAKAAAA 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100 212 DTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADA-SEEDPTPAGEEDVKDAREEDGVDTIEEDltragEEDG 290
Cdd:PRK05901  89 KAPAKKKLKDELDSSKKAEKKNALDKDDDLNYVKDIDVLNQAdDDDDDDDDDDLDDDDIDDDDDDEDDDED-----DDDD 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 767950100 291 KDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDTITNEKAHSILNFLK 345
Cdd:PRK05901 164 DVDDEDEEKKEAKELEKLSDDDDFVWDEDDSEALRQARKDAKLTATADPVKAYLK 218
PRK12678 PRK12678
transcription termination factor Rho; Provisional
 192-331 1.74e-03

transcription termination factor Rho; Provisional


Pssm-ID: 237171 [Multi-domain]  Cd Length: 672  Bit Score: 41.43  E-value: 1.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100 192 PEDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDlTRARQEEGADASEedptpAGEEDVKDARE 271
Cdd:PRK12678  73 PAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAP-EAAQARERRERGE-----AARRGAARKAG 146

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100 272 EDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDT 331
Cdd:PRK12678 147 EGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAERGERGRREERGRDGDDRDRR 206
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 213-331 2.69e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 40.77  E-value: 2.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100  213 TSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEEDGKD 292
Cdd:COG5271   482 TDEDDASDDGDEEEAEEDAEAEADSDELTAEETSADDGADTDAAADPEDSDEDALEDETEGEENAPGSDQDADETDEPEA 561

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 767950100  293 TREEDGADASEEDPTWAGEEEGADSGEEDGADASEEDDT 331
Cdd:COG5271   562 TAEEDEPDEAEAETEDATENADADETEESADESEEAEAS 600
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 195-335 2.97e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 40.35  E-value: 2.97e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100 195 SSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGA--DASEEDLTRARQEE-GADASEEDptpagEEDVKDARE 271
Cdd:PRK13108 322 EPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGESTPAveETSEADIEREQPGDlAGQAPAAH-----QVDAEAASA 396

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767950100 272 EDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTwAGEEEGADSGEEDGADASEEDDTITNE 335
Cdd:PRK13108 397 APEEPAALASEAHDETEPEVPEKAAPIPDPAKPDEL-AVAGPGDDPAEPDGIRRQDDFSSRRRR 459
TFIIF_alpha pfam05793
Transcription initiation factor IIF, alpha subunit (TFIIF-alpha); Transcription initiation ...
 193-336 3.21e-03

Transcription initiation factor IIF, alpha subunit (TFIIF-alpha); Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) or RNA polymerase II-associating protein 74 (RAP74) is the large subunit of transcription factor IIF (TFIIF), which is essential for accurate initiation and stimulates elongation by RNA polymerase II.


Pssm-ID: 310411 [Multi-domain]  Cd Length: 528  Bit Score: 40.32  E-value: 3.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100  193 EDSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDltRARQEEGADASEEDPTPAGEEDVKDAREE 272
Cdd:pfam05793 197 EETEGEKGGGGRGKDLKIKDLEGDDEDDGDESDKGGEDGDEEKKKKKKK--KLAKNKKKLDDDKKKKRGGDDDAFEYDSD 274

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767950100  273 DGVD-TIEEDLTRAGEEDGKDTREEDGADASEEDPtwAGEEEGADSGEEDGADASEEDDTITNEK 336
Cdd:pfam05793 275 DGDDeGREEDYISDSSASGNDPEEREDKLSPEEPA--KGEIEQSDDSEESEEEKNEEEGKLSKKG 337
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 192-305 4.17e-03

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 39.91  E-value: 4.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100  192 PEDSSNEGEGVGEACEEDGVDTSEEDptlagEEDvkdtrEEDGADASEEDltrarqeegaDASEEDPtpagEEDVKDARE 271
Cdd:pfam04931 625 ARENPEGQQELFEDEDEDEEDDDEEE-----DDD-----DEDDEDSEEDD----------DEDDDDE----DEEDDDDED 680

                          90       100       110
                  ....*....|....*....|....*....|....
gi 767950100  272 EDGVDTIEEDLTRAGEEDGKDtrEEDGADASEED 305
Cdd:pfam04931 681 VDEIDELRAKLAEALGEHGDD--ADDDDSDSDED 712
COG5593 COG5593
Nucleic-acid-binding protein possibly involved in ribosomal biogenesis [Translation, ribosomal ...
 185-339 7.02e-03

Nucleic-acid-binding protein possibly involved in ribosomal biogenesis [Translation, ribosomal structure and biogenesis];


Pssm-ID: 227880 [Multi-domain]  Cd Length: 821  Bit Score: 39.25  E-value: 7.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100 185 GVSFMyQPEdSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTRE-------EDGADASEEDLTRARQEEGADASEED 257
Cdd:COG5593  612 GTSIM-QPL-FSGVNDSLVKASMHDQGPVNTEDWLTKKVEDIKPEDKffyqyftKKTADGKGKKSNKASFDSDDEMDENE 689

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100 258 PTPA---GEEDVKDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEGADS------GEEDGAD---- 324
Cdd:COG5593  690 IWSAlvkSRPDVEDDSDDSELDFAEDDFSDSTSDDEPKLDAIDDEDAKSEGSQESDQEEGLDEifysfdGEQDNSDsfae 769

                        170       180
                 ....*....|....*....|.
gi 767950100 325 ------ASEEDDTITNEKAHS 339
Cdd:COG5593  770 sseedeSSEEEKEEEENKEVS 790
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 260-330 7.04e-03

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 39.14  E-value: 7.04e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767950100  260 PAGEEDVKDAREEDGVDTIEEDltragEEDgkdtrEEDGADASEEDptwAGEEEGADSGEEDGADASEEDD 330
Cdd:pfam04931 629 PEGQQELFEDEDEDEEDDDEEE-----DDD-----DEDDEDSEEDD---DEDDDDEDEEDDDDEDVDEIDE 686
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 194-335 9.44e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 38.84  E-value: 9.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100  194 DSSNEGEGVGEACEEDGVDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDVKDAREED 273
Cdd:COG5271   479 DEATDEDDASDDGDEEEAEEDAEAEADSDELTAEETSADDGADTDAAADPEDSDEDALEDETEGEENAPGSDQDADETDE 558

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767950100  274 GVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAGEEEG-ADSGEEDGADASEEDDTITNE 335
Cdd:COG5271   559 PEATAEEDEPDEAEAETEDATENADADETEESADESEEAEAsEDEAAEEEEADDDEADADADG 621
CobT2 COG4547
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ...
 222-318 9.68e-03

Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 443611 [Multi-domain]  Cd Length: 608  Bit Score: 38.62  E-value: 9.68e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767950100 222 GEEDVKDTREEDGADASEEDLTRARQEEGADASEEDPTPAGEEDvkdarEEDGVDTIEEDLTRAGEEDGKDTREEDGADA 301
Cdd:COG4547  208 AEELGEDEDEEDEDDEDDSGEQEEDEEDGEDEDEESDEGAEAED-----AEASGDDAEEGESEAAEAESDEMAEEAEGED 282

                         90       100
                 ....*....|....*....|..
gi 767950100 302 SEE-----DPTWAGEEEGADSG 318
Cdd:COG4547  283 SEEpgepwRPNAPPPDDPADPD 304
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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