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Conserved domains on  [gi|578812804|ref|XP_006715565|]
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peroxisomal biogenesis factor 7 isoform X1 [Homo sapiens]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 1000017)

WD40 repeat domain-containing protein similar to a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WD40 super family cl29593
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 67-219 8.52e-22

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


The actual alignment was detected with superfamily member cd00200:

Pssm-ID: 475233 [Multi-domain]  Cd Length: 289  Bit Score: 90.86  E-value: 8.52e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804  67 NDGLFDVTWSENNEHvLITCSGDGSLQLWDTAKAAgPLQVYKEH----------AQENLLVTGAVDCSLRGWDLRNvRQP 136
Cdd:cd00200    9 TGGVTCVAFSPDGKL-LATGSGDGTIKVWDLETGE-LLRTLKGHtgpvrdvaasADGTYLASGSSDKTIRLWDLET-GEC 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804 137 VFELLGHTYAIRRVKFSPfHASVLASCSYDFTVRFWNFSKPDSLLeTVEHHTEFTCGLDFSlQSPTQVADCSWDETIKIY 216
Cdd:cd00200   86 VRTLTGHTSYVSSVAFSP-DGRILSSSSRDKTIKVWDVETGKCLT-TLRGHTDWVNSVAFS-PDGTFVASSSQDGTIKLW 162


                 ...
gi 578812804 217 DPA 219
Cdd:cd00200  163 DLR 165
 
Name Accession Description Interval E-value
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 67-219 8.52e-22

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 90.86  E-value: 8.52e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804  67 NDGLFDVTWSENNEHvLITCSGDGSLQLWDTAKAAgPLQVYKEH----------AQENLLVTGAVDCSLRGWDLRNvRQP 136
Cdd:cd00200    9 TGGVTCVAFSPDGKL-LATGSGDGTIKVWDLETGE-LLRTLKGHtgpvrdvaasADGTYLASGSSDKTIRLWDLET-GEC 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804 137 VFELLGHTYAIRRVKFSPfHASVLASCSYDFTVRFWNFSKPDSLLeTVEHHTEFTCGLDFSlQSPTQVADCSWDETIKIY 216
Cdd:cd00200   86 VRTLTGHTSYVSSVAFSP-DGRILSSSSRDKTIKVWDVETGKCLT-TLRGHTDWVNSVAFS-PDGTFVASSSQDGTIKLW 162


                 ...
gi 578812804 217 DPA 219
Cdd:cd00200  163 DLR 165
WD40 COG2319
WD40 repeat [General function prediction only];
46-219 1.91e-20

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 88.43  E-value: 1.91e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804  46 GTLLILDPDeAGLRLFRSFDWNDGLFDVTWSENNEHvLITCSGDGSLQLWDTAKAAgPLQVYKEHAQE----------NL 115
Cdd:COG2319  100 GTVRLWDLA-TGLLLRTLTGHTGAVRSVAFSPDGKT-LASGSADGTVRLWDLATGK-LLRTLTGHSGAvtsvafspdgKL 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804 116 LVTGAVDCSLRGWDLRNvRQPVFELLGHTYAIRRVKFSPfHASVLASCSYDFTVRFWNFSKPdSLLETVEHHTEFTCGLD 195
Cdd:COG2319  177 LASGSDDGTVRLWDLAT-GKLLRTLTGHTGAVRSVAFSP-DGKLLASGSADGTVRLWDLATG-KLLRTLTGHSGSVRSVA 253

                        170       180
                 ....*....|....*....|....
gi 578812804 196 FSLQSPTqVADCSWDETIKIYDPA 219
Cdd:COG2319  254 FSPDGRL-LASGSADGTVRLWDLA 276
PTZ00421 PTZ00421
coronin; Provisional
 116-223 3.00e-09

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 56.05  E-value: 3.00e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804 116 LVTGAVDCSLRGWDL------RNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSlLETVEHHTE 189
Cdd:PTZ00421  91 LFTASEDGTIMGWGIpeegltQNISDPIVHLQGHTKKVGIVSFHPSAMNVLASAGADMVVNVWDVERGKA-VEVIKCHSD 169

                         90       100       110
                 ....*....|....*....|....*....|....
gi 578812804 190 FTCGLDFSLQSpTQVADCSWDETIKIYDPACLTI 223
Cdd:PTZ00421 170 QITSLEWNLDG-SLLCTTSKDKKLNIIDPRDGTI 202
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 134-173 3.35e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 42.68  E-value: 3.35e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 578812804   134 RQPVFELLGHTYAIRRVKFSPfHASVLASCSYDFTVRFWN 173
Cdd:smart00320   2 GELLKTLKGHTGPVTSVAFSP-DGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
134-173 2.57e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 40.41  E-value: 2.57e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 578812804  134 RQPVFELLGHTYAIRRVKFSPFHaSVLASCSYDFTVRFWN 173
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDG-KLLASGSDDGTVKVWD 39
 
Name Accession Description Interval E-value
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 67-219 8.52e-22

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 90.86  E-value: 8.52e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804  67 NDGLFDVTWSENNEHvLITCSGDGSLQLWDTAKAAgPLQVYKEH----------AQENLLVTGAVDCSLRGWDLRNvRQP 136
Cdd:cd00200    9 TGGVTCVAFSPDGKL-LATGSGDGTIKVWDLETGE-LLRTLKGHtgpvrdvaasADGTYLASGSSDKTIRLWDLET-GEC 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804 137 VFELLGHTYAIRRVKFSPfHASVLASCSYDFTVRFWNFSKPDSLLeTVEHHTEFTCGLDFSlQSPTQVADCSWDETIKIY 216
Cdd:cd00200   86 VRTLTGHTSYVSSVAFSP-DGRILSSSSRDKTIKVWDVETGKCLT-TLRGHTDWVNSVAFS-PDGTFVASSSQDGTIKLW 162


                 ...
gi 578812804 217 DPA 219
Cdd:cd00200  163 DLR 165
WD40 COG2319
WD40 repeat [General function prediction only];
46-219 1.91e-20

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 88.43  E-value: 1.91e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804  46 GTLLILDPDeAGLRLFRSFDWNDGLFDVTWSENNEHvLITCSGDGSLQLWDTAKAAgPLQVYKEHAQE----------NL 115
Cdd:COG2319  100 GTVRLWDLA-TGLLLRTLTGHTGAVRSVAFSPDGKT-LASGSADGTVRLWDLATGK-LLRTLTGHSGAvtsvafspdgKL 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804 116 LVTGAVDCSLRGWDLRNvRQPVFELLGHTYAIRRVKFSPfHASVLASCSYDFTVRFWNFSKPdSLLETVEHHTEFTCGLD 195
Cdd:COG2319  177 LASGSDDGTVRLWDLAT-GKLLRTLTGHTGAVRSVAFSP-DGKLLASGSADGTVRLWDLATG-KLLRTLTGHSGSVRSVA 253

                        170       180
                 ....*....|....*....|....
gi 578812804 196 FSLQSPTqVADCSWDETIKIYDPA 219
Cdd:COG2319  254 FSPDGRL-LASGSADGTVRLWDLA 276
WD40 COG2319
WD40 repeat [General function prediction only];
10-219 1.24e-19

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 86.12  E-value: 1.24e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804  10 RMLRTPGRHG---YAAEFSPylPGRLAcATAQHYGiagcgTLLILDPDEAglRLFRSFD-WNDGLFDVTWSENNeHVLIT 85
Cdd:COG2319  153 KLLRTLTGHSgavTSVAFSP--DGKLL-ASGSDDG-----TVRLWDLATG--KLLRTLTgHTGAVRSVAFSPDG-KLLAS 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804  86 CSGDGSLQLWDTAKAAgPLQVYKEHAQE----------NLLVTGAVDCSLRGWDLRNvRQPVFELLGHTYAIRRVKFSPf 155
Cdd:COG2319  222 GSADGTVRLWDLATGK-LLRTLTGHSGSvrsvafspdgRLLASGSADGTVRLWDLAT-GELLRTLTGHSGGVNSVAFSP- 298

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578812804 156 HASVLASCSYDFTVRFWNFSKPdSLLETVEHHTEFTCGLDFSlQSPTQVADCSWDETIKIYDPA 219
Cdd:COG2319  299 DGKLLASGSDDGTVRLWDLATG-KLLRTLTGHTGAVRSVAFS-PDGKTLASGSDDGTVRLWDLA 360
WD40 COG2319
WD40 repeat [General function prediction only];
6-219 2.87e-19

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 85.35  E-value: 2.87e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804   6 GGAARMLRTPGRHGYAAEFSPylPGR-LACATAQhygiagcGTLLILDPDeAGLRLFRSFDWNDGLFDVTWSENNEHvLI 84
Cdd:COG2319  194 GKLLRTLTGHTGAVRSVAFSP--DGKlLASGSAD-------GTVRLWDLA-TGKLLRTLTGHSGSVRSVAFSPDGRL-LA 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804  85 TCSGDGSLQLWDTAKAAgPLQVYKEHAQE----------NLLVTGAVDCSLRGWDLRNvRQPVFELLGHTYAIRRVKFSP 154
Cdd:COG2319  263 SGSADGTVRLWDLATGE-LLRTLTGHSGGvnsvafspdgKLLASGSDDGTVRLWDLAT-GKLLRTLTGHTGAVRSVAFSP 340

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578812804 155 fHASVLASCSYDFTVRFWNFSKPdSLLETVEHHTEFTCGLDFSLQSPTqVADCSWDETIKIYDPA 219
Cdd:COG2319  341 -DGKTLASGSDDGTVRLWDLATG-ELLRTLTGHTGAVTSVAFSPDGRT-LASGSADGTVRLWDLA 402
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 67-217 4.12e-17

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 77.76  E-value: 4.12e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804  67 NDGLFDVTWSENNeHVLITCSGDGSLQLWDtAKAAGPLQVYKEH----------AQENLLVTGAVDCSLRGWDLRNvRQP 136
Cdd:cd00200  135 TDWVNSVAFSPDG-TFVASSSQDGTIKLWD-LRTGKCVATLTGHtgevnsvafsPDGEKLLSSSSDGTIKLWDLST-GKC 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804 137 VFELLGHTYAIRRVKFSPfHASVLASCSYDFTVRFWNfSKPDSLLETVEHHTEFTCGLDFSlQSPTQVADCSWDETIKIY 216
Cdd:cd00200  212 LGTLRGHENGVNSVAFSP-DGYLLASGSEDGTIRVWD-LRTGECVQTLSGHTNSVTSLAWS-PDGKRLASGSADGTIRIW 288


                 .
gi 578812804 217 D 217
Cdd:cd00200  289 D 289
WD40 COG2319
WD40 repeat [General function prediction only];
8-219 2.00e-16

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 77.26  E-value: 2.00e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804   8 AARMLRTPGRHGYAAEFSPYLPGRLACATAQHYGIAGCGTLLILDPDEAGLRLFRSFDWNDGLFDVTWSENNEHVLITCS 87
Cdd:COG2319   18 LALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASAS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804  88 GDGSLQLWDTAkAAGPLQVYKEHAQE----------NLLVTGAVDCSLRGWDLRNvRQPVFELLGHTYAIRRVKFSPfHA 157
Cdd:COG2319   98 ADGTVRLWDLA-TGLLLRTLTGHTGAvrsvafspdgKTLASGSADGTVRLWDLAT-GKLLRTLTGHSGAVTSVAFSP-DG 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578812804 158 SVLASCSYDFTVRFWNFSKPDsLLETVEHHTEFTCGLDFSLQSpTQVADCSWDETIKIYDPA 219
Cdd:COG2319  175 KLLASGSDDGTVRLWDLATGK-LLRTLTGHTGAVRSVAFSPDG-KLLASGSADGTVRLWDLA 234
PTZ00421 PTZ00421
coronin; Provisional
 116-223 3.00e-09

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 56.05  E-value: 3.00e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804 116 LVTGAVDCSLRGWDL------RNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSlLETVEHHTE 189
Cdd:PTZ00421  91 LFTASEDGTIMGWGIpeegltQNISDPIVHLQGHTKKVGIVSFHPSAMNVLASAGADMVVNVWDVERGKA-VEVIKCHSD 169

                         90       100       110
                 ....*....|....*....|....*....|....
gi 578812804 190 FTCGLDFSLQSpTQVADCSWDETIKIYDPACLTI 223
Cdd:PTZ00421 170 QITSLEWNLDG-SLLCTTSKDKKLNIIDPRDGTI 202
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 136-217 2.79e-07

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 50.03  E-value: 2.79e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804 136 PVFELLGHTYAIRRVKFSPfHASVLASCSYDFTVRFWNFsKPDSLLETVEHHTEFTCGLDFSLQSpTQVADCSWDETIKI 215
Cdd:cd00200    1 LRRTLKGHTGGVTCVAFSP-DGKLLATGSGDGTIKVWDL-ETGELLRTLKGHTGPVRDVAASADG-TYLASGSSDKTIRL 77


                 ..
gi 578812804 216 YD 217
Cdd:cd00200   78 WD 79
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 134-173 3.35e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 42.68  E-value: 3.35e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 578812804   134 RQPVFELLGHTYAIRRVKFSPfHASVLASCSYDFTVRFWN 173
Cdd:smart00320   2 GELLKTLKGHTGPVTSVAFSP-DGKYLASGSDDGTIKLWD 40
PTZ00420 PTZ00420
coronin; Provisional
 136-178 7.58e-06

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 46.10  E-value: 7.58e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 578812804 136 PVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPD 178
Cdd:PTZ00420  66 PVIKLKGHTSSILDLQFNPCFSEILASGSEDLTIRVWEIPHND 108
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 70-175 2.16e-05

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 44.69  E-value: 2.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804  70 LFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGP-----------LQVYKEHAQEnlLVTGAVDCSLRGWDLRNVRQPVF 138
Cdd:PLN00181 578 VWSIDYSSADPTLLASGSDDGSVKLWSINQGVSIgtiktkaniccVQFPSESGRS--LAFGSADHKVYYYDLRNPKLPLC 655

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 578812804 139 ELLGHTYAIRRVKFspFHASVLASCSYDFTVRFWNFS 175
Cdd:PLN00181 656 TMIGHSKTVSYVRF--VDSSTLVSSSTDNTLKLWDLS 690
WD40 pfam00400
WD domain, G-beta repeat;
134-173 2.57e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 40.41  E-value: 2.57e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 578812804  134 RQPVFELLGHTYAIRRVKFSPFHaSVLASCSYDFTVRFWN 173
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDG-KLLASGSDDGTVKVWD 39
WD40 COG2319
WD40 repeat [General function prediction only];
10-132 2.25e-04

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 41.44  E-value: 2.25e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804  10 RMLRTPGRHG---YAAEFSPylPGR-LACATAQhygiagcGTLLILDPDEAglRLFRSFD-WNDGLFDVTWSENNEHvLI 84
Cdd:COG2319  279 ELLRTLTGHSggvNSVAFSP--DGKlLASGSDD-------GTVRLWDLATG--KLLRTLTgHTGAVRSVAFSPDGKT-LA 346

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 578812804  85 TCSGDGSLQLWDTAkAAGPLQVYKEHAQE----------NLLVTGAVDCSLRGWDLRN 132
Cdd:COG2319  347 SGSDDGTVRLWDLA-TGELLRTLTGHTGAvtsvafspdgRTLASGSADGTVRLWDLAT 403
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 129-216 1.16e-03

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 39.68  E-value: 1.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578812804 129 DLRNVRQPVFELLGHTyAIRRVKFSPFHASVLASCSYDFTVRFWNFSKpDSLLETVEHHTEFTCGLDFSLQSPTQVADCS 208
Cdd:PLN00181 518 DGRDIHYPVVELASRS-KLSGICWNSYIKSQVASSNFEGVVQVWDVAR-SQLVTEMKEHEKRVWSIDYSSADPTLLASGS 595


                 ....*...
gi 578812804 209 WDETIKIY 216
Cdd:PLN00181 596 DDGSVKLW 603
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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