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Conserved domains on  [gi|569003827|ref|XP_006525981|]
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dmX-like protein 1 isoform X3 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Rav1p_C super family cl13644
RAVE protein 1 C terminal; This domain family is found in eukaryotes, and is typically between ...
 1139-1875 1.17e-74

RAVE protein 1 C terminal; This domain family is found in eukaryotes, and is typically between 621 and 644 amino acids in length. This family is the C terminal region of the protein RAVE (regulator of the ATPase of vacuolar and endosomal membranes). Rav1p is involved in regulating the glucose dependent assembly and disassembly of vacuolar ATPase V1 and V0 subunits.


The actual alignment was detected with superfamily member pfam12234:

Pssm-ID: 432413  Cd Length: 637  Bit Score: 263.27  E-value: 1.17e-74
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1139 LDWMSREDGSHILTVGIGSKLFMYGPMAgkvqdqtgkenqafplWDSTKIVPLskFVLLRSVDLVSSVegapPFPVS-LS 1217
Cdd:pfam12234   76 LDWTSTPDSQSILAVGFPHHVLLLTQLR----------------YDYTNKGPS--WAPIRKIDIRDLT----PHPIGdSI 133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1218 WVRDGILVVGMDCEMHVYSQWqpsnkqepvisesyngstpsilslIKQSNSSSSGLHppkktltrsmtslaQKICGKKSi 1297
Cdd:pfam12234  134 WLDDGTLVVAAGNQLFIYDKW------------------------LDLRLPDDPFTL--------------RSIGSRKI- 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1298 fdPSVDmedsgLFEAAHVLSPTLPQYHPLQLLELMDLGKVRRAKAILSHLVKCIagevvalneaesnherrlrsltisas 1377
Cdd:pfam12234  175 --LSND-----LFHLVSVLNGPLPVYHPQFLIQCLLAGKLELVKEILLRLFKEL-------------------------- 221

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1378 gsttrdpqafnKADSRDYTEIDSVPPLPLYALLAADDDSYcsslektgseSSLKKSKQLSKESYDELFQTsvlmsdnhml 1457
Cdd:pfam12234  222 -----------KFYSEDLEDLDSFLGIDLEKFLKDDDKAY----------SKNKAFTSSSDDDDPDPYET---------- 270

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1458 etdeentqprvidlsqysptyFGPEHAQVLSGHLLHSSLPGLTRMEQMSLMALADTIATTstdigesrdrNQGGETLDEC 1537
Cdd:pfam12234  271 ---------------------FNEEVASSLNEKLTKISLPQLTRHEQITLINVIEAVGEV----------EKHRRSLDEN 319

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1538 GLKFLLAVRLHTflttslpAYRAQLLHQGLSTGHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNARILR 1617
Cdd:pfam12234  320 GARFLLGFKLHL-------LHKKRTSQSSLSWRDISWALHSDNQEILLDLVSRHYGNKLLWEAARESGIFMWLKDIEALR 392

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1618 RCIEKVAKAAFHRNN--DPLDAAIFYLAMKKKAVIWGLYRS------QKdtKMTQFFGHNFEEERWRKAALKNAFSLLGK 1689
Cdd:pfam12234  393 AQFEVIARNEYTKSDerDPVDCSLFYLALKKKQVLQGLWRMaswhpeQA--KTLKFLSNDFSEPRWRTAALKNAFALLSK 470

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1690 QRFEHSAAFFLLGGCLKDAIEVCLEKLNDIQLALVIARLFESefDKSATYKSILRKKVLGIGSPaselssssinaHHDPF 1769
Cdd:pfam12234  471 HRYEYAAAFFLLADSLKDAVNVLLRQLKDLQLAIAVARVYEG--DDGPVLRELLEERVLPLAIK-----------EGDRW 537

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1770 LRSMAHWILEDYSAALETLIKQPVT-EDEDQVMMSACNPIVFNfyNYLRTHPLL------LRRhfgsssetfSTHMTLAG 1842
Cdd:pfam12234  538 LASWAFWMLKRRDLAVRALVTPPYDlLENTDLKKSDPASPVSK--SFLTDDPALvllyqqLRK---------KTLQTLKG 606

                          730       740       750
                   ....*....|....*....|....*....|...
gi 569003827  1843 KSGLAGTInlsERRLFFTTASAHLKAGCPMLAL 1875
Cdd:pfam12234  607 ALKVTPKE---EYDFVLRVARIYDRMGCDLLAL 636
WD40 super family cl29593
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 2754-3011 1.76e-22

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


The actual alignment was detected with superfamily member cd00200:

Pssm-ID: 475233 [Multi-domain]  Cd Length: 289  Bit Score: 100.49  E-value: 1.76e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2754 VRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRsGGNSRITRMRFNYQGNKFGIVDADGYLSLYQTNWKCCPVTgs 2833
Cdd:cd00200    12 VTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLK-GHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRT-- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2834 mpkpylaWQCHNKTANDFVFVSSSSLIATaglSSDNRNICLWDTlvaPANSLVHAFTCHDSGATVLAYAPKHQLLISGGR 2913
Cdd:cd00200    89 -------LTGHTSYVSSVAFSPDGRILSS---SSRDKTIKVWDV---ETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQ 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2914 KGFTCIFDLRQRQQRQLFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSSFSLLHTFIneharqsIFRNIGTGVMQI 2993
Cdd:cd00200   156 DGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLR-------GHENGVNSVAFS 228

                         250
                  ....*....|....*...
gi 569003827 2994 ETGpaNHIFSCGADGTMK 3011
Cdd:cd00200   229 PDG--YLLASGSEDGTIR 244
WD40 super family cl43672
WD40 repeat [General function prediction only];
114-265 3.68e-03

WD40 repeat [General function prediction only];


The actual alignment was detected with superfamily member COG2319:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 42.59  E-value: 3.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  114 HNITWDPAGNRLLTGSSclqlwcnsrkqtedenpDKTdlnfgnwMCIWHCKTASQVHLMK----------FSPDGEFFAT 183
Cdd:COG2319   208 RSVAFSPDGKLLASGSA-----------------DGT-------VRLWDLATGKLLRTLTghsgsvrsvaFSPDGRLLAS 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  184 AGkDDCLLKVWyNVENWRPAVTSPDknsekqsqgeidfsfvylaHPRAVNGFSWRKTSKYmprasvcnvLLTCCKDNVCR 263
Cdd:COG2319   264 GS-ADGTVRLW-DLATGELLRTLTG-------------------HSGGVNSVAFSPDGKL---------LASGSDDGTVR 313


                  ..
gi 569003827  264 LW 265
Cdd:COG2319   314 LW 315
 
Name Accession Description Interval E-value
Rav1p_C pfam12234
RAVE protein 1 C terminal; This domain family is found in eukaryotes, and is typically between ...
 1139-1875 1.17e-74

RAVE protein 1 C terminal; This domain family is found in eukaryotes, and is typically between 621 and 644 amino acids in length. This family is the C terminal region of the protein RAVE (regulator of the ATPase of vacuolar and endosomal membranes). Rav1p is involved in regulating the glucose dependent assembly and disassembly of vacuolar ATPase V1 and V0 subunits.


Pssm-ID: 432413  Cd Length: 637  Bit Score: 263.27  E-value: 1.17e-74
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1139 LDWMSREDGSHILTVGIGSKLFMYGPMAgkvqdqtgkenqafplWDSTKIVPLskFVLLRSVDLVSSVegapPFPVS-LS 1217
Cdd:pfam12234   76 LDWTSTPDSQSILAVGFPHHVLLLTQLR----------------YDYTNKGPS--WAPIRKIDIRDLT----PHPIGdSI 133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1218 WVRDGILVVGMDCEMHVYSQWqpsnkqepvisesyngstpsilslIKQSNSSSSGLHppkktltrsmtslaQKICGKKSi 1297
Cdd:pfam12234  134 WLDDGTLVVAAGNQLFIYDKW------------------------LDLRLPDDPFTL--------------RSIGSRKI- 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1298 fdPSVDmedsgLFEAAHVLSPTLPQYHPLQLLELMDLGKVRRAKAILSHLVKCIagevvalneaesnherrlrsltisas 1377
Cdd:pfam12234  175 --LSND-----LFHLVSVLNGPLPVYHPQFLIQCLLAGKLELVKEILLRLFKEL-------------------------- 221

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1378 gsttrdpqafnKADSRDYTEIDSVPPLPLYALLAADDDSYcsslektgseSSLKKSKQLSKESYDELFQTsvlmsdnhml 1457
Cdd:pfam12234  222 -----------KFYSEDLEDLDSFLGIDLEKFLKDDDKAY----------SKNKAFTSSSDDDDPDPYET---------- 270

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1458 etdeentqprvidlsqysptyFGPEHAQVLSGHLLHSSLPGLTRMEQMSLMALADTIATTstdigesrdrNQGGETLDEC 1537
Cdd:pfam12234  271 ---------------------FNEEVASSLNEKLTKISLPQLTRHEQITLINVIEAVGEV----------EKHRRSLDEN 319

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1538 GLKFLLAVRLHTflttslpAYRAQLLHQGLSTGHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNARILR 1617
Cdd:pfam12234  320 GARFLLGFKLHL-------LHKKRTSQSSLSWRDISWALHSDNQEILLDLVSRHYGNKLLWEAARESGIFMWLKDIEALR 392

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1618 RCIEKVAKAAFHRNN--DPLDAAIFYLAMKKKAVIWGLYRS------QKdtKMTQFFGHNFEEERWRKAALKNAFSLLGK 1689
Cdd:pfam12234  393 AQFEVIARNEYTKSDerDPVDCSLFYLALKKKQVLQGLWRMaswhpeQA--KTLKFLSNDFSEPRWRTAALKNAFALLSK 470

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1690 QRFEHSAAFFLLGGCLKDAIEVCLEKLNDIQLALVIARLFESefDKSATYKSILRKKVLGIGSPaselssssinaHHDPF 1769
Cdd:pfam12234  471 HRYEYAAAFFLLADSLKDAVNVLLRQLKDLQLAIAVARVYEG--DDGPVLRELLEERVLPLAIK-----------EGDRW 537

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1770 LRSMAHWILEDYSAALETLIKQPVT-EDEDQVMMSACNPIVFNfyNYLRTHPLL------LRRhfgsssetfSTHMTLAG 1842
Cdd:pfam12234  538 LASWAFWMLKRRDLAVRALVTPPYDlLENTDLKKSDPASPVSK--SFLTDDPALvllyqqLRK---------KTLQTLKG 606

                          730       740       750
                   ....*....|....*....|....*....|...
gi 569003827  1843 KSGLAGTInlsERRLFFTTASAHLKAGCPMLAL 1875
Cdd:pfam12234  607 ALKVTPKE---EYDFVLRVARIYDRMGCDLLAL 636
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 2754-3011 1.76e-22

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 100.49  E-value: 1.76e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2754 VRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRsGGNSRITRMRFNYQGNKFGIVDADGYLSLYQTNWKCCPVTgs 2833
Cdd:cd00200    12 VTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLK-GHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRT-- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2834 mpkpylaWQCHNKTANDFVFVSSSSLIATaglSSDNRNICLWDTlvaPANSLVHAFTCHDSGATVLAYAPKHQLLISGGR 2913
Cdd:cd00200    89 -------LTGHTSYVSSVAFSPDGRILSS---SSRDKTIKVWDV---ETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQ 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2914 KGFTCIFDLRQRQQRQLFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSSFSLLHTFIneharqsIFRNIGTGVMQI 2993
Cdd:cd00200   156 DGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLR-------GHENGVNSVAFS 228

                         250
                  ....*....|....*...
gi 569003827 2994 ETGpaNHIFSCGADGTMK 3011
Cdd:cd00200   229 PDG--YLLASGSEDGTIR 244
WD40 COG2319
WD40 repeat [General function prediction only];
2677-3011 1.81e-19

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 93.82  E-value: 1.81e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2677 SAILATQIYTWVDDDTETETKGSEDFLVIHARDDLSAVQGSTPYTHSNPGTPINMPWLGSTQTGRGASvmLKKAINNVRR 2756
Cdd:COG2319     6 GAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLAT--LLGHTAAVLS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2757 MTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRsGGNSRITRMRFNYQGNKFGIVDADGYLSLYQTNwkccpvTGsmpK 2836
Cdd:COG2319    84 VAFSPDGRLLASASADGTVRLWDLATGLLLRTLT-GHTGAVRSVAFSPDGKTLASGSADGTVRLWDLA------TG---K 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2837 PYLAWQCHNKTANDFVFVSSSSLIATAglsSDNRNICLWDtlvAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGF 2916
Cdd:COG2319   154 LLRTLTGHSGAVTSVAFSPDGKLLASG---SDDGTVRLWD---LATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGT 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2917 TCIFDLRQRQQRQLFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSSFSLLHTFINEHARqsifrnigtgVMQIETG 2996
Cdd:COG2319   228 VRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGG----------VNSVAFS 297

                         330
                  ....*....|....*.
gi 569003827 2997 P-ANHIFSCGADGTMK 3011
Cdd:COG2319   298 PdGKLLASGSDDGTVR 313
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 2931-2963 6.00e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 42.30  E-value: 6.00e-05
                            10        20        30
                    ....*....|....*....|....*....|...
gi 569003827   2931 FQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWS 2963
Cdd:smart00320    8 LKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
2931-2963 3.68e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 40.41  E-value: 3.68e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 569003827  2931 FQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWS 2963
Cdd:pfam00400    7 LEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 COG2319
WD40 repeat [General function prediction only];
114-265 3.68e-03

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 42.59  E-value: 3.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  114 HNITWDPAGNRLLTGSSclqlwcnsrkqtedenpDKTdlnfgnwMCIWHCKTASQVHLMK----------FSPDGEFFAT 183
Cdd:COG2319   208 RSVAFSPDGKLLASGSA-----------------DGT-------VRLWDLATGKLLRTLTghsgsvrsvaFSPDGRLLAS 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  184 AGkDDCLLKVWyNVENWRPAVTSPDknsekqsqgeidfsfvylaHPRAVNGFSWRKTSKYmprasvcnvLLTCCKDNVCR 263
Cdd:COG2319   264 GS-ADGTVRLW-DLATGELLRTLTG-------------------HSGGVNSVAFSPDGKL---------LASGSDDGTVR 313


                  ..
gi 569003827  264 LW 265
Cdd:COG2319   314 LW 315
 
Name Accession Description Interval E-value
Rav1p_C pfam12234
RAVE protein 1 C terminal; This domain family is found in eukaryotes, and is typically between ...
 1139-1875 1.17e-74

RAVE protein 1 C terminal; This domain family is found in eukaryotes, and is typically between 621 and 644 amino acids in length. This family is the C terminal region of the protein RAVE (regulator of the ATPase of vacuolar and endosomal membranes). Rav1p is involved in regulating the glucose dependent assembly and disassembly of vacuolar ATPase V1 and V0 subunits.


Pssm-ID: 432413  Cd Length: 637  Bit Score: 263.27  E-value: 1.17e-74
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1139 LDWMSREDGSHILTVGIGSKLFMYGPMAgkvqdqtgkenqafplWDSTKIVPLskFVLLRSVDLVSSVegapPFPVS-LS 1217
Cdd:pfam12234   76 LDWTSTPDSQSILAVGFPHHVLLLTQLR----------------YDYTNKGPS--WAPIRKIDIRDLT----PHPIGdSI 133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1218 WVRDGILVVGMDCEMHVYSQWqpsnkqepvisesyngstpsilslIKQSNSSSSGLHppkktltrsmtslaQKICGKKSi 1297
Cdd:pfam12234  134 WLDDGTLVVAAGNQLFIYDKW------------------------LDLRLPDDPFTL--------------RSIGSRKI- 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1298 fdPSVDmedsgLFEAAHVLSPTLPQYHPLQLLELMDLGKVRRAKAILSHLVKCIagevvalneaesnherrlrsltisas 1377
Cdd:pfam12234  175 --LSND-----LFHLVSVLNGPLPVYHPQFLIQCLLAGKLELVKEILLRLFKEL-------------------------- 221

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1378 gsttrdpqafnKADSRDYTEIDSVPPLPLYALLAADDDSYcsslektgseSSLKKSKQLSKESYDELFQTsvlmsdnhml 1457
Cdd:pfam12234  222 -----------KFYSEDLEDLDSFLGIDLEKFLKDDDKAY----------SKNKAFTSSSDDDDPDPYET---------- 270

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1458 etdeentqprvidlsqysptyFGPEHAQVLSGHLLHSSLPGLTRMEQMSLMALADTIATTstdigesrdrNQGGETLDEC 1537
Cdd:pfam12234  271 ---------------------FNEEVASSLNEKLTKISLPQLTRHEQITLINVIEAVGEV----------EKHRRSLDEN 319

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1538 GLKFLLAVRLHTflttslpAYRAQLLHQGLSTGHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNARILR 1617
Cdd:pfam12234  320 GARFLLGFKLHL-------LHKKRTSQSSLSWRDISWALHSDNQEILLDLVSRHYGNKLLWEAARESGIFMWLKDIEALR 392

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1618 RCIEKVAKAAFHRNN--DPLDAAIFYLAMKKKAVIWGLYRS------QKdtKMTQFFGHNFEEERWRKAALKNAFSLLGK 1689
Cdd:pfam12234  393 AQFEVIARNEYTKSDerDPVDCSLFYLALKKKQVLQGLWRMaswhpeQA--KTLKFLSNDFSEPRWRTAALKNAFALLSK 470

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1690 QRFEHSAAFFLLGGCLKDAIEVCLEKLNDIQLALVIARLFESefDKSATYKSILRKKVLGIGSPaselssssinaHHDPF 1769
Cdd:pfam12234  471 HRYEYAAAFFLLADSLKDAVNVLLRQLKDLQLAIAVARVYEG--DDGPVLRELLEERVLPLAIK-----------EGDRW 537

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  1770 LRSMAHWILEDYSAALETLIKQPVT-EDEDQVMMSACNPIVFNfyNYLRTHPLL------LRRhfgsssetfSTHMTLAG 1842
Cdd:pfam12234  538 LASWAFWMLKRRDLAVRALVTPPYDlLENTDLKKSDPASPVSK--SFLTDDPALvllyqqLRK---------KTLQTLKG 606

                          730       740       750
                   ....*....|....*....|....*....|...
gi 569003827  1843 KSGLAGTInlsERRLFFTTASAHLKAGCPMLAL 1875
Cdd:pfam12234  607 ALKVTPKE---EYDFVLRVARIYDRMGCDLLAL 636
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 2754-3011 1.76e-22

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 100.49  E-value: 1.76e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2754 VRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRsGGNSRITRMRFNYQGNKFGIVDADGYLSLYQTNWKCCPVTgs 2833
Cdd:cd00200    12 VTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLK-GHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRT-- 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2834 mpkpylaWQCHNKTANDFVFVSSSSLIATaglSSDNRNICLWDTlvaPANSLVHAFTCHDSGATVLAYAPKHQLLISGGR 2913
Cdd:cd00200    89 -------LTGHTSYVSSVAFSPDGRILSS---SSRDKTIKVWDV---ETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQ 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2914 KGFTCIFDLRQRQQRQLFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSSFSLLHTFIneharqsIFRNIGTGVMQI 2993
Cdd:cd00200   156 DGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLR-------GHENGVNSVAFS 228

                         250
                  ....*....|....*...
gi 569003827 2994 ETGpaNHIFSCGADGTMK 3011
Cdd:cd00200   229 PDG--YLLASGSEDGTIR 244
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 2792-3012 2.80e-20

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 93.94  E-value: 2.80e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2792 GGNSRITRMRFNYQGNKFGIVDADGYLSLYQTNWKCCPVTGsmpkpylawQCHNKTANDFVFVSSSSLIATAglsSDNRN 2871
Cdd:cd00200     7 GHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTL---------KGHTGPVRDVAASADGTYLASG---SSDKT 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2872 ICLWDTlvaPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTCIFDLRQRQQRQLFQSHDSPVKAIAIDPTEEYFV 2951
Cdd:cd00200    75 IRLWDL---ETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVA 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 569003827 2952 TGSAEGNIKIWSLSSFSLLHTFineharqSIFRNIGTGVMQIETGpaNHIFSCGADGTMKM 3012
Cdd:cd00200   152 SSSQDGTIKLWDLRTGKCVATL-------TGHTGEVNSVAFSPDG--EKLLSSSSDGTIKL 203
WD40 COG2319
WD40 repeat [General function prediction only];
2677-3011 1.81e-19

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 93.82  E-value: 1.81e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2677 SAILATQIYTWVDDDTETETKGSEDFLVIHARDDLSAVQGSTPYTHSNPGTPINMPWLGSTQTGRGASvmLKKAINNVRR 2756
Cdd:COG2319     6 GAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLAT--LLGHTAAVLS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2757 MTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRsGGNSRITRMRFNYQGNKFGIVDADGYLSLYQTNwkccpvTGsmpK 2836
Cdd:COG2319    84 VAFSPDGRLLASASADGTVRLWDLATGLLLRTLT-GHTGAVRSVAFSPDGKTLASGSADGTVRLWDLA------TG---K 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2837 PYLAWQCHNKTANDFVFVSSSSLIATAglsSDNRNICLWDtlvAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGF 2916
Cdd:COG2319   154 LLRTLTGHSGAVTSVAFSPDGKLLASG---SDDGTVRLWD---LATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGT 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2917 TCIFDLRQRQQRQLFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSSFSLLHTFINEHARqsifrnigtgVMQIETG 2996
Cdd:COG2319   228 VRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGG----------VNSVAFS 297

                         330
                  ....*....|....*.
gi 569003827 2997 P-ANHIFSCGADGTMK 3011
Cdd:COG2319   298 PdGKLLASGSDDGTVR 313
WD40 COG2319
WD40 repeat [General function prediction only];
2767-3011 1.67e-18

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 90.74  E-value: 1.67e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2767 LTGAQDGSVRMFEWGHSQQITCFRsGGNSRITRMRFNYQGNKFGIVDADGYLSLYQTNwkccpvTGsmpKPYLAWQCHNK 2846
Cdd:COG2319   136 ASGSADGTVRLWDLATGKLLRTLT-GHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLA------TG---KLLRTLTGHTG 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2847 TANDFVFVSSSSLIATAglsSDNRNICLWDtlvAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTCIFDLRQRQ 2926
Cdd:COG2319   206 AVRSVAFSPDGKLLASG---SADGTVRLWD---LATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGE 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2927 QRQLFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSSFSLLHTFINEHARqsifrnigtgVMQIETGPA-NHIFSCG 3005
Cdd:COG2319   280 LLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGA----------VRSVAFSPDgKTLASGS 349


                  ....*.
gi 569003827 3006 ADGTMK 3011
Cdd:COG2319   350 DDGTVR 355
WD40 COG2319
WD40 repeat [General function prediction only];
2768-3011 3.85e-17

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 86.50  E-value: 3.85e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2768 TGAQDGSVRMFEWGHSQQITCFRsGGNSRITRMRFNYQGNKFGIVDADGYLSLYQTNwkccpvTGSMPKPylaWQCHNKT 2847
Cdd:COG2319   179 SGSDDGTVRLWDLATGKLLRTLT-GHTGAVRSVAFSPDGKLLASGSADGTVRLWDLA------TGKLLRT---LTGHSGS 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2848 ANDFVFVSSSSLIATAglsSDNRNICLWDtlvAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTCIFDLRQRQQ 2927
Cdd:COG2319   249 VRSVAFSPDGRLLASG---SADGTVRLWD---LATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKL 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2928 RQLFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSSFSLLHTFiNEHARqsifrnigtGVMQIETGPA-NHIFSCGA 3006
Cdd:COG2319   323 LRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTL-TGHTG---------AVTSVAFSPDgRTLASGSA 392


                  ....*
gi 569003827 3007 DGTMK 3011
Cdd:COG2319   393 DGTVR 397
WD40 COG2319
WD40 repeat [General function prediction only];
2768-2966 2.25e-16

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 84.19  E-value: 2.25e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2768 TGAQDGSVRMFEWGHSQQITCFRsGGNSRITRMRFNYQGNKFGIVDADGYLSLYQTNwkccpvTGSMPKPYLAwqcHNKT 2847
Cdd:COG2319   221 SGSADGTVRLWDLATGKLLRTLT-GHSGSVRSVAFSPDGRLLASGSADGTVRLWDLA------TGELLRTLTG---HSGG 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2848 ANDFVFVSSSSLIATAglsSDNRNICLWDtlvAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTCIFDLRQRQQ 2927
Cdd:COG2319   291 VNSVAFSPDGKLLASG---SDDGTVRLWD---LATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGEL 364

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 569003827 2928 RQLFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSLSS 2966
Cdd:COG2319   365 LRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 2752-2963 4.94e-15

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 78.53  E-value: 4.94e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2752 NNVRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRsGGNSRITRMRFNyQGNKFGIV-DADGYLSLYQT-NWKCCP 2829
Cdd:cd00200    94 SYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLR-GHTDWVNSVAFS-PDGTFVASsSQDGTIKLWDLrTGKCVA 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2830 V-TGsmpkpylawqcHNKTANDFVFVSSSSLIATaglSSDNRNICLWDTLVApanSLVHAFTCHDSGATVLAYAPKHQLL 2908
Cdd:cd00200   172 TlTG-----------HTGEVNSVAFSPDGEKLLS---SSSDGTIKLWDLSTG---KCLGTLRGHENGVNSVAFSPDGYLL 234

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 569003827 2909 ISGGRKGFTCIFDLRQRQQRQLFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWS 2963
Cdd:cd00200   235 ASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 2885-3012 1.44e-09

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 61.97  E-value: 1.44e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827 2885 LVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTCIFDLRQRQQRQLFQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWSL 2964
Cdd:cd00200     1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 569003827 2965 SSFSLLHTFinEHARQSIFrnigtGVMQIetgPANHIF-SCGADGTMKM 3012
Cdd:cd00200    81 ETGECVRTL--TGHTSYVS-----SVAFS---PDGRILsSSSRDKTIKV 119
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 2931-2963 6.00e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 42.30  E-value: 6.00e-05
                            10        20        30
                    ....*....|....*....|....*....|...
gi 569003827   2931 FQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWS 2963
Cdd:smart00320    8 LKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
2931-2963 3.68e-04

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 40.41  E-value: 3.68e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 569003827  2931 FQSHDSPVKAIAIDPTEEYFVTGSAEGNIKIWS 2963
Cdd:pfam00400    7 LEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 COG2319
WD40 repeat [General function prediction only];
114-265 3.68e-03

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 42.59  E-value: 3.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  114 HNITWDPAGNRLLTGSSclqlwcnsrkqtedenpDKTdlnfgnwMCIWHCKTASQVHLMK----------FSPDGEFFAT 183
Cdd:COG2319   208 RSVAFSPDGKLLASGSA-----------------DGT-------VRLWDLATGKLLRTLTghsgsvrsvaFSPDGRLLAS 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003827  184 AGkDDCLLKVWyNVENWRPAVTSPDknsekqsqgeidfsfvylaHPRAVNGFSWRKTSKYmprasvcnvLLTCCKDNVCR 263
Cdd:COG2319   264 GS-ADGTVRLW-DLATGELLRTLTG-------------------HSGGVNSVAFSPDGKL---------LASGSDDGTVR 313


                  ..
gi 569003827  264 LW 265
Cdd:COG2319   314 LW 315
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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