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Conserved domains on  [gi|568967097|ref|XP_006513487|]
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excitatory amino acid transporter 4 isoform X3 [Mus musculus]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
51-543 1.63e-117

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 354.03  E-value: 1.63e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097  51 RRNAFILLTVSAVIIGVSLAFALRPYQLSYrqikyFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAA 129
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLPELVAAV-----LKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 130 VYYMVTTVIAVFIGILMVTIIHPGKGSKEGLHREGRIETVPTADaFMDLVRNMFPPNLVEAcfkqfktqystrvvtrtiv 209
Cdd:COG1301   76 LYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------- 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 210 rtdngselgasmsptssvenetsilenvtralgtlqevisfeetvpvpgSANGiNALGLVVFSVAFGLVIGGMKHKGRVL 289
Cdd:COG1301  136 -------------------------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPL 165

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 290 RDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMeDMAVLGgQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFP 369
Cdd:COG1301  166 LDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLK 243

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 370 FIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQIT 449
Cdd:COG1301  244 FLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQL 323

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 450 TISLssripdslpvcsiTATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVI 529
Cdd:COG1301  324 TIVL-------------TAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390

                        490
                 ....*....|....
gi 568967097 530 EHlSQRELELQEAE 543
Cdd:COG1301  391 AK-WEGELDREKLN 403
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
51-543 1.63e-117

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 354.03  E-value: 1.63e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097  51 RRNAFILLTVSAVIIGVSLAFALRPYQLSYrqikyFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAA 129
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLPELVAAV-----LKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 130 VYYMVTTVIAVFIGILMVTIIHPGKGSKEGLHREGRIETVPTADaFMDLVRNMFPPNLVEAcfkqfktqystrvvtrtiv 209
Cdd:COG1301   76 LYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------- 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 210 rtdngselgasmsptssvenetsilenvtralgtlqevisfeetvpvpgSANGiNALGLVVFSVAFGLVIGGMKHKGRVL 289
Cdd:COG1301  136 -------------------------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPL 165

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 290 RDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMeDMAVLGgQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFP 369
Cdd:COG1301  166 LDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLK 243

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 370 FIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQIT 449
Cdd:COG1301  244 FLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQL 323

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 450 TISLssripdslpvcsiTATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVI 529
Cdd:COG1301  324 TIVL-------------TAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390

                        490
                 ....*....|....
gi 568967097 530 EHlSQRELELQEAE 543
Cdd:COG1301  391 AK-WEGELDREKLN 403
SDF pfam00375
Sodium:dicarboxylate symporter family;
55-532 2.63e-110

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 334.88  E-value: 2.63e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097   55 FILLTVSAVIIGVSLAFALRPYqlsyrqIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVYYM 133
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPEL------AAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097  134 VTTVIAVFIGILMVTIIHPGKGSKeGLHREGRIETVPTADAFMDLVRNMFPPNLVEACFKQfktqystrvvtrtivrtdn 213
Cdd:pfam00375  75 VTTAIAALIGLLVANVFQPGSGLA-LIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEG------------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097  214 gselgasmsptssvenetsilenvtralgtlqevisfeetvpvpgsangiNALGLVVFSVAFGLVIGGMKHKGRVLRDFF 293
Cdd:pfam00375 135 --------------------------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFI 164

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097  294 DSLNEAIMRLVGIIIWYAPVGILFLIAGKILEmEDMAVLGgQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFPFIGG 373
Cdd:pfam00375 165 ESLQEVMMKVIGWVMKLAPIGVFALIANTVGT-YGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKK 242

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097  374 MLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISL 453
Cdd:pfam00375 243 MLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVL 322

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568967097  454 ssripdslpvcsiTATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHL 532
Cdd:pfam00375 323 -------------TATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 60-529 2.28e-38

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 146.35  E-value: 2.28e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097  60 VSAVIIGVSLAFALRPYQLSYRQIkyfsfpGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVYYMVTTVI 138
Cdd:PRK13027  13 VIALVLGVALGAFFPHFAESLKPL------GDGFIKLIKMLIGPIVFCVVVSGIAGAgDLKKVGRVGLKAVIYFEVMTTI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 139 AVFIGILMVTIIHPGKGskeglhregrietvptadAFMDLvrnmfppnlveacfkqfktqystrvvtrtivRTDNGSELG 218
Cdd:PRK13027  87 ALVIGLVLAYLTGPGVG------------------MNIDL-------------------------------RSLDAASLA 117

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 219 ASMSPTSSVENETSILENVTralgtlqevisfeETVPVPGSANGiNALGLVVFSVAFGLVIGGMKHKGRVLRDFFDSLNE 298
Cdd:PRK13027 118 GYAKNAQSLKGTAGFLLKLI-------------PTTAVDAFAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSH 183

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 299 AIMRLVGIIIWYAPVGILFLIA---GKiLEMEDMAVLGGQLGMYTLTVIVGLFLHAGGVLPLIYFLVthrnpFPFIGGML 375
Cdd:PRK13027 184 VLFRIMGFIIKLAPLGVLGAIAfttGK-YGVGSLKQLGMLVAVFYLTCFVFVVVVLGAVMRLAGFSV-----FKLIRYLR 257

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 376 QALITAMGTSSSSATLPITFRCLEEgLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISLSS 455
Cdd:PRK13027 258 EELLIVLGTASSDAVLPQVMRKLEH-MGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVS 336

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568967097 456 RIpdslpvcsitataASVGAAGIPQAGLVTMVIVLTSVG-LPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVI 529
Cdd:PRK13027 337 LV-------------TSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGNCVATVVV 398
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
51-543 1.63e-117

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 354.03  E-value: 1.63e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097  51 RRNAFILLTVSAVIIGVSLAFALRPYQLSYrqikyFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAA 129
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLPELVAAV-----LKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 130 VYYMVTTVIAVFIGILMVTIIHPGKGSKEGLHREGRIETVPTADaFMDLVRNMFPPNLVEAcfkqfktqystrvvtrtiv 209
Cdd:COG1301   76 LYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------- 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 210 rtdngselgasmsptssvenetsilenvtralgtlqevisfeetvpvpgSANGiNALGLVVFSVAFGLVIGGMKHKGRVL 289
Cdd:COG1301  136 -------------------------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPL 165

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 290 RDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMeDMAVLGgQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFP 369
Cdd:COG1301  166 LDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLK 243

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 370 FIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQIT 449
Cdd:COG1301  244 FLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQL 323

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 450 TISLssripdslpvcsiTATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVI 529
Cdd:COG1301  324 TIVL-------------TAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390

                        490
                 ....*....|....
gi 568967097 530 EHlSQRELELQEAE 543
Cdd:COG1301  391 AK-WEGELDREKLN 403
SDF pfam00375
Sodium:dicarboxylate symporter family;
55-532 2.63e-110

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 334.88  E-value: 2.63e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097   55 FILLTVSAVIIGVSLAFALRPYqlsyrqIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVYYM 133
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPEL------AAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097  134 VTTVIAVFIGILMVTIIHPGKGSKeGLHREGRIETVPTADAFMDLVRNMFPPNLVEACFKQfktqystrvvtrtivrtdn 213
Cdd:pfam00375  75 VTTAIAALIGLLVANVFQPGSGLA-LIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEG------------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097  214 gselgasmsptssvenetsilenvtralgtlqevisfeetvpvpgsangiNALGLVVFSVAFGLVIGGMKHKGRVLRDFF 293
Cdd:pfam00375 135 --------------------------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFI 164

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097  294 DSLNEAIMRLVGIIIWYAPVGILFLIAGKILEmEDMAVLGgQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFPFIGG 373
Cdd:pfam00375 165 ESLQEVMMKVIGWVMKLAPIGVFALIANTVGT-YGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKK 242

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097  374 MLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISL 453
Cdd:pfam00375 243 MLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVL 322

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568967097  454 ssripdslpvcsiTATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHL 532
Cdd:pfam00375 323 -------------TATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 60-529 2.28e-38

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 146.35  E-value: 2.28e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097  60 VSAVIIGVSLAFALRPYQLSYRQIkyfsfpGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVYYMVTTVI 138
Cdd:PRK13027  13 VIALVLGVALGAFFPHFAESLKPL------GDGFIKLIKMLIGPIVFCVVVSGIAGAgDLKKVGRVGLKAVIYFEVMTTI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 139 AVFIGILMVTIIHPGKGskeglhregrietvptadAFMDLvrnmfppnlveacfkqfktqystrvvtrtivRTDNGSELG 218
Cdd:PRK13027  87 ALVIGLVLAYLTGPGVG------------------MNIDL-------------------------------RSLDAASLA 117

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 219 ASMSPTSSVENETSILENVTralgtlqevisfeETVPVPGSANGiNALGLVVFSVAFGLVIGGMKHKGRVLRDFFDSLNE 298
Cdd:PRK13027 118 GYAKNAQSLKGTAGFLLKLI-------------PTTAVDAFAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSH 183

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 299 AIMRLVGIIIWYAPVGILFLIA---GKiLEMEDMAVLGGQLGMYTLTVIVGLFLHAGGVLPLIYFLVthrnpFPFIGGML 375
Cdd:PRK13027 184 VLFRIMGFIIKLAPLGVLGAIAfttGK-YGVGSLKQLGMLVAVFYLTCFVFVVVVLGAVMRLAGFSV-----FKLIRYLR 257

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 376 QALITAMGTSSSSATLPITFRCLEEgLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISLSS 455
Cdd:PRK13027 258 EELLIVLGTASSDAVLPQVMRKLEH-MGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVS 336

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568967097 456 RIpdslpvcsitataASVGAAGIPQAGLVTMVIVLTSVG-LPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVI 529
Cdd:PRK13027 337 LV-------------TSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGNCVATVVV 398
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 60-545 2.25e-35

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 137.73  E-value: 2.25e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097  60 VSAVIIGV-------SLAFALRPYqlsyrqikyfsfpGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVY 131
Cdd:PRK01663  14 LVAIIIGIllghfypELGAQMKPL-------------GDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKALLY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 132 YMVTTVIAVFIGILMVTIIHPGKGskeglhregrietvptadafmdlvRNMFPPNLVEACFKQFktqystrvvtrtivrT 211
Cdd:PRK01663  81 FEIVSTIALIIGLIVVNVVQPGAG------------------------MNIDPATLDAKAVAQY---------------A 121

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 212 DNGSELGAsmsptssvenetsilenvtraLGTLQEVISfeeTVPVPGSANGiNALGLVVFSVAFGLVIGGMKHKGRVLRD 291
Cdd:PRK01663 122 AQAHEQGT---------------------VDFLMDIIP---TTVVGAFASG-DILQVLLFAVLFGFALARLGEKGKPVFD 176

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 292 FFDSLNEAIMRLVGIIIWYAPVGILFLIAGKI--LEMEDMAVLGGQLGMYTLTVIVGLFLHAGGVLPLIYFlvthrNPFP 369
Cdd:PRK01663 177 FIESLSHVLFGIVNMIMKLAPIGAFGAMAFTIgkYGVGSLVQLGQLIGCFYITCILFVFVVLGAIARLTGF-----SIFK 251

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 370 FIGGMLQALITAMGTSSSSATLPITFRCLEEgLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQIT 449
Cdd:PRK01663 252 FIRYIKEELLIVLGTSSSESALPRMMEKMEK-LGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQI 330

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 450 TIslssripdsLPVCSITataaSVGAAGIPQAGLVTMVIVLTSVG-LPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAV 528
Cdd:PRK01663 331 TL---------LAVLLLT----SKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGVATVV 397

                        490
                 ....*....|....*..
gi 568967097 529 IehlSQRELELQEAELT 545
Cdd:PRK01663 398 V---AKWEKELDREKLD 411
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 62-529 5.92e-35

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 136.82  E-value: 5.92e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097  62 AVIIGVSLAFALRpYQLSYRQ---IKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVYYMVTTV 137
Cdd:PRK11283  15 ALVLGILLGAYLH-YHSDSRDwlvSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVITT 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 138 IAVFIGILMVTIIHPGKGSKEGL--------HREGRIETVPTADAFMDLVRNMFPPNLVeacfkqfktqystrvvtrtiv 209
Cdd:PRK11283  94 VAIILGITLANVFQPGAGIDMSQlatvdiskYQSTTEEVQSHSHGLMGTILSLIPTNIF--------------------- 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 210 rtdngselgASMsptssvenetsilenvtrALGtlqevisfeETVPVpgsanginalglVVFSVAFGLVIGGMKHKGRV- 288
Cdd:PRK11283 153 ---------ASM------------------AKG---------EMLPI------------IFFSVLFGLGLSSLPATHREp 184

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 289 LRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLggQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRnPF 368
Cdd:PRK11283 185 LVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLW--PLAKLVLLVYFAILFFALVVLGIVARLCGLS-IW 261

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 369 PFIGGMLQALITAMGTSSSSATLPitfRCLE--EGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLG 446
Cdd:PRK11283 262 ILIRILKDELILAYSTASSETVLP---RIIEkmEAYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIW 338

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 447 QITTISLssripdslpvcsiTATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGA 526
Cdd:PRK11283 339 QEIILVL-------------TLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAV 405


                 ...
gi 568967097 527 AVI 529
Cdd:PRK11283 406 LVI 408
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 260-478 9.64e-17

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 82.60  E-value: 9.64e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 260 ANGINAL------GLVVFSVAFGLvigGMKHKGRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLG 333
Cdd:PRK13628 136 DNPINALlnanyiGILAWAIGLGL---ALRHASDTTKNVVNDLSEAVSQIVKWVIRFAPIGIFGLVASTLAETGFSALAG 212

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 334 -GQLgmytLTVIVG-LFLHAGGVLPLIYFLVTHRNPFPFIggmLQAL----ITAMGTSSSSATLPITFRcLEEGLGVDRR 407
Cdd:PRK13628 213 yAQL----LAVLVGcMLFVALVVNPLIVFWKIRRNPYPLV---FTCLresgVTAFFTRSSAANIPVNMA-LCEKLGLDED 284

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568967097 408 ITRFVLPVGATVNMDGtalyealAAIFIAQvnnyeLNLGQITTISLSSRIPDSLpVCSITATAASVGAAGI 478
Cdd:PRK13628 285 TYSVSIPLGATINMAG-------AAITITV-----LTLAAVHTLGIPVDLPTAL-LLSVVAAISACGASGV 342
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
 61-529 9.96e-17

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 82.95  E-value: 9.96e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097  61 SAVIIGVSLAFALrpyQLSY--------RQIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASLDN-KATGRMGMRAAVY 131
Cdd:COG1823   36 TGLGLGILFGLIL---QLIYgagspvikQSIDWFNIVGNGYVRLLQMIVMPLVFVSILSAITKLKNaSSLGKISGLIIGI 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 132 YMVTTVIAVFIGILMVTIIhpgkgskeGLhregrietvpTADAFMDLVRNmfppnlveacfkqfktqystrvvtrtivrT 211
Cdd:COG1823  113 LLGTTAIAALVGILVALLF--------GL----------TAEGLTQGAAE-----------------------------T 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 212 DNGSELgasmsptssvENETSILENVTRAlgtlQEVISFEETVP---VPGsANGINALGLVVFSVAFGLVIGGMKHK--- 285
Cdd:COG1823  146 ARGEAL----------EERLGEVEDLSLP----QQILSFIPTNPfadLTG-ARPTSTIAVVIFAAFLGIAALGLRRKkpe 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 286 -GRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAgKIL---EMEDMAVLGG-----QLGMYTLTVIVGLFLHAGGVLP 356
Cdd:COG1823  211 qAETFLKGIDALQAIVMRLVRLVLRLTPYGVLALMT-KVVatsDFADILNLGKfvvasYVALIIMFIVHLLLLALAGLNP 289

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 357 LIYFlvthRNPFPfiggmlqALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTA-LYEALAAIFI 435
Cdd:COG1823  290 LTYF----KKVWP-------VLTFAFTSRSSAGTIPLNIETQTKRLGVPEGIANFAASFGATIGQNGCAgIYPAMLAVMI 358

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 436 AQ---VNNYE----LNLGQITTISlssripdslpvcsitataaSVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDW 508
Cdd:COG1823  359 APtvgINPLDpsfiLTLIAVVTIS-------------------SFGVAGVGGGATFAALIVLSAMGLPVALAGLLISIEP 419

                        490       500
                 ....*....|....*....|.
gi 568967097 509 FLDRLRTMTNVlGDSIGAAVI 529
Cdd:COG1823  420 LIDMGRTALNV-SGSMTAGTV 439
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
260-479 6.09e-16

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 79.83  E-value: 6.09e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 260 ANGINAL------GLVVFSVAFGLvigGMKHKGRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLG 333
Cdd:COG3633  135 DNPVNALananyiGILAWAIGLGL---ALRHASDTTKTVLSDLSDAVSKIVRWVIRFAPLGIFGLVASTVATTGFSALLG 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 334 -GQLgmytLTVIVG-LFLHAGGVLPLIYFLVTHRNPFPFIggmLQAL----ITAMGTSSSSATLPITFRcLEEGLGVDRR 407
Cdd:COG3633  212 yAHL----LAVLVGcMLFVALVVNPLIVFLKIRRNPYPLV---FTCLresgITAFFTRSSAANIPVNMA-LCEKLGLDED 283

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568967097 408 ITRFVLPVGATVNMDGtalyealAAIFIAQvnnyeLNLGQITTISLSSRIPDSLpVCSITATAASVGAAGIP 479
Cdd:COG3633  284 TYSVSIPLGATINMAG-------AAITITV-----LTLAAVHTLGIEVDLPTAL-LLSVVAAVSACGASGVA 342
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
 264-536 4.70e-10

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 61.22  E-value: 4.70e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 264 NALGLVVFSVAFGLvigGMKHKGRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVlgGQLGMYTLTV 343
Cdd:PRK14695  60 NYIGILSWAVIFGI---AMREASKNSKELLKTIADVTSKIVEWIINLAPFGILGLVFKTISDKGVGSL--ANYGILLVLL 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 344 IVGLFLHAGGVLPLIYFLVTHRNPFPFIGGMLQ-ALITAMGTSSSSATLPITFRcLEEGLGVDRRITRFVLPVGATVNMD 422
Cdd:PRK14695 135 VTTMLFVAPVVNPLIAFFFMRRNPYPLVWNCLRvSGVTAFFTRSSATNIPVNMK-LCHDLGLNPDTYSVSIPLGSTINMA 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568967097 423 GTALyeALAAIFIAQVNNYELNLGQITTIslssripdslpVCSITATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITL 502
Cdd:PRK14695 214 GVAI--TINLLTLVTVNTLGIPVDFATAF-----------VLSVVAAISACGASGIAGGSLLLIPVACSLFGISNDIAIQ 280

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 568967097 503 IIAVDWFL----DRLRTMTNVLGDSIGAAVIEHLSQRE 536
Cdd:PRK14695 281 IVGVGFVIgviqDSCETALNSSTDVLFTAVAEYAATRK 318
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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