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Conserved domains on  [gi|568961907|ref|XP_006511433|]
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propionyl-CoA carboxylase beta chain, mitochondrial isoform X1 [Mus musculus]

Protein Classification

acyl-CoA carboxylase subunit beta( domain architecture ID 11469175)

acyl-CoA carboxylase subunit beta, such as propionyl-CoA carboxylase subunit beta, which is the catalytic carboxyltransferase subunit of the enzyme that catalyzes the carboxylation of propionyl-CoA to form methylmalonyl-CoA

CATH:  3.90.226.10
EC:  6.-.-.-
Gene Ontology:  GO:0016874
PubMed:  8102604
SCOP:  4000456

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MmdA COG4799
Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];
39-499 0e+00

Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];


:

Pssm-ID: 443827 [Multi-domain]  Cd Length: 508  Bit Score: 732.21  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  39 ERIDNKRHAALLGGGQRRIDAQHKR-----------------------------------FPGDSVVTGRGRINGRLVYV 83
Cdd:COG4799    7 AELRARREEALLGGGEKAIERQHARgkltareridllldpgsflelgalaghrmyddddrVPGDGVVTGIGTVDGRPVVV 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  84 FSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCA 163
Cdd:COG4799   87 VANDFTVKGGSLGPMTAKKILRAQDIALENGLPVIYLVDSGGARLQEGVESFAGYGRIFYRNARSSGGIPQISVIMGPCA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 164 GGAVYSPALTDFTFMVKDTSYLFITGPEVVKSVTNEDVTQEQLGGAKTHTTVSGVAHRAFDNDVDALCNLREFFNFLPLS 243
Cdd:COG4799  167 AGGAYSPALSDFVIMVKGTSQMFLGGPPVVKAATGEEVTAEELGGADVHARVSGVADYLAEDEEEALALARRLLSYLPSN 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 244 SQDPAPIRECHDPsDRLVPELDTVVPLESSKAYNMLDIIHAVIDEREFFEIMPSYAKNIVVGFARMNGRTVGIVGNQPNV 323
Cdd:COG4799  247 NLEDPPRAEPAPP-ARDPEELYGIVPEDPRKPYDMREVIARLVDGGSFFEFKPLYGPNIVTGFARIDGRPVGIVANQPMV 325

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 324 ASGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYGGAYDV 403
Cdd:COG4799  326 LAGVLDIDAADKAARFIRLCDAFNIPLVFLVDVPGFMVGTEQERGGIIRHGAKLLYAVAEATVPKITVILRKAYGAGYYA 405

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 404 MSSKHLLGDTNYAWPTAEIAVMGAKGAVEIIFK----GHQDVEAAQAEYVEKF---ANPFPAAVRGFVDDIIQPSSTRAR 476
Cdd:COG4799  406 MCGKALGPDFLFAWPTAEIAVMGGEGAANVLYRrelaAAEDPEALRAELIAEYeeqANPYYAAARGWIDDVIDPRDTRRV 485

                        490       500
                 ....*....|....*....|...
gi 568961907 477 ICCDLEVLASKKVHRPWRKHANI 499
Cdd:COG4799  486 LARALEAAANKPEERPPKKHGVI 508
 
Name Accession Description Interval E-value
MmdA COG4799
Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];
39-499 0e+00

Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];


Pssm-ID: 443827 [Multi-domain]  Cd Length: 508  Bit Score: 732.21  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  39 ERIDNKRHAALLGGGQRRIDAQHKR-----------------------------------FPGDSVVTGRGRINGRLVYV 83
Cdd:COG4799    7 AELRARREEALLGGGEKAIERQHARgkltareridllldpgsflelgalaghrmyddddrVPGDGVVTGIGTVDGRPVVV 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  84 FSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCA 163
Cdd:COG4799   87 VANDFTVKGGSLGPMTAKKILRAQDIALENGLPVIYLVDSGGARLQEGVESFAGYGRIFYRNARSSGGIPQISVIMGPCA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 164 GGAVYSPALTDFTFMVKDTSYLFITGPEVVKSVTNEDVTQEQLGGAKTHTTVSGVAHRAFDNDVDALCNLREFFNFLPLS 243
Cdd:COG4799  167 AGGAYSPALSDFVIMVKGTSQMFLGGPPVVKAATGEEVTAEELGGADVHARVSGVADYLAEDEEEALALARRLLSYLPSN 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 244 SQDPAPIRECHDPsDRLVPELDTVVPLESSKAYNMLDIIHAVIDEREFFEIMPSYAKNIVVGFARMNGRTVGIVGNQPNV 323
Cdd:COG4799  247 NLEDPPRAEPAPP-ARDPEELYGIVPEDPRKPYDMREVIARLVDGGSFFEFKPLYGPNIVTGFARIDGRPVGIVANQPMV 325

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 324 ASGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYGGAYDV 403
Cdd:COG4799  326 LAGVLDIDAADKAARFIRLCDAFNIPLVFLVDVPGFMVGTEQERGGIIRHGAKLLYAVAEATVPKITVILRKAYGAGYYA 405

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 404 MSSKHLLGDTNYAWPTAEIAVMGAKGAVEIIFK----GHQDVEAAQAEYVEKF---ANPFPAAVRGFVDDIIQPSSTRAR 476
Cdd:COG4799  406 MCGKALGPDFLFAWPTAEIAVMGGEGAANVLYRrelaAAEDPEALRAELIAEYeeqANPYYAAARGWIDDVIDPRDTRRV 485

                        490       500
                 ....*....|....*....|...
gi 568961907 477 ICCDLEVLASKKVHRPWRKHANI 499
Cdd:COG4799  486 LARALEAAANKPEERPPKKHGVI 508
Carboxyl_trans pfam01039
Carboxyl transferase domain; All of the members in this family are biotin dependent ...
 62-499 0e+00

Carboxyl transferase domain; All of the members in this family are biotin dependent carboxylases. The carboxyl transferase domain carries out the following reaction; transcarboxylation from biotin to an acceptor molecule. There are two recognized types of carboxyl transferase. One of them uses acyl-CoA and the other uses 2-oxoacid as the acceptor molecule of carbon dioxide. All of the members in this family utilize acyl-CoA as the acceptor molecule.


Pssm-ID: 426008 [Multi-domain]  Cd Length: 491  Bit Score: 655.10  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907   62 KRFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAGYADI 141
Cdd:pfam01039  40 KRIPRDGVVTGSGAVIGRAVEVVAQDFTVFGGSLGPAKGEKILRAMEIAIKTGLPLIGINDSGGARIQEGVENLRGSGKI 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  142 FLRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFMVKDTSYLFITGPEVVKSVTNEDVTQEQLGGAKTHTTVSGVAHR 221
Cdd:pfam01039 120 FGRNSLASGVIPQISLIMGPCAGGGAYLPALGDFVIMVEGTSPMFLTGPPVIKKVTGEEVTSEELGGATQHMTISGVSHL 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  222 AFDNDVDALCNLREFFNFLPL---SSQDPAPIRECHDPSDRLVPeLDTVVPLESSKAYNMLDIIHAVIDEREFFEIMPSY 298
Cdd:pfam01039 200 TALDDEDALELIRKWLSYLPKpapNNREPVPIVPTKDPPDRDAP-LVSIVPDDPKKPYDVREVIAGIVDEGEFFEIKPGY 278

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  299 AKNIVVGFARMNGRTVGIVGNQPNVASGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLL 378
Cdd:pfam01039 279 AKTVVTGFARLGGIPVGVVANQPRVGAGVLFPDSADKAARFIRDCDAFNLPLVILADVPGFLPGQRQEYGGILKHGAKLL 358

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  379 YAFAEATVPKITVITRKAYGGAYDVMSSKHLLGDTNYAWPTAEIAVMGAKGAVEIIF--------KGHQDVEAA----QA 446
Cdd:pfam01039 359 YALAEATVPKITVIPRKAYGGAYVVMDSKINGADINFAWPTARIAVMGPEGAVEIKFrkekaaaeMRGKDLAATrkqkIA 438

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568961907  447 EYVEKFANPFPAAVRGFVDDIIQPSSTRARICCDLEVLASKKVHRPWRKHANI 499
Cdd:pfam01039 439 EYEEELSPPYVAAARGFADAVIDPGRTRAKLVIALAALWTKPRFFPWRKHGNI 491
mmdA TIGR01117
methylmalonyl-CoA decarboxylase alpha subunit; This model describes methymalonyl-CoA ...
 39-501 0e+00

methylmalonyl-CoA decarboxylase alpha subunit; This model describes methymalonyl-CoA decarboxylase aplha subunit in archaea and bacteria. Metylmalonyl-CoA decarboxylase Na+ pump is a representative of a class of Na+ transport decarboxylases that couples the energy derived by decarboxylation of carboxylic acid substrates to drive the extrusion of Na+ ion across the membrane. [Energy metabolism, ATP-proton motive force interconversion, Energy metabolism, Fermentation, Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130187  Cd Length: 512  Bit Score: 624.55  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907   39 ERIDNKRHAALLGGGQRRIDAQH--------------------------------------KRFPGDSVVTGRGRINGRL 80
Cdd:TIGR01117   4 EELHEKKEKIKQGGGEKRIEKQHaqgkmtarerlallfdpgsfveidqfvkhrctnfgmdkKELPAEGVVTGYGTIDGRL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907   81 VYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMG 160
Cdd:TIGR01117  84 VYAFAQDFTVMGGSLGEMHAAKIVKIMDLAMKMGAPVVGLNDSGGARIQEAVDALKGYGDIFYRNTIASGVVPQISAIMG 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  161 PCAGGAVYSPALTDFTFMVKDTSYLFITGPEVVKSVTNEDVTQEQLGGAKTHTTVSGVAHRAFDNDVDALCNLREFFNFL 240
Cdd:TIGR01117 164 PCAGGAVYSPALTDFIYMVDNTSQMFITGPQVIKTVTGEEVTAEQLGGAMAHNSVSGVAHFIAEDDDDCIMLIRRLLSFL 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  241 PLSSQDPAPIRECHDPSDRLVPELDTVVPLESSKAYNMLDIIHAVIDEREFFEIMPSYAKNIVVGFARMNGRTVGIVGNQ 320
Cdd:TIGR01117 244 PSNNMEKAPLVKTGDDPTRETPELYDLLPDNPNKPYDMRDVITAIVDNGDYLEVQPYYAPNIITCFARINGQSVGIIANQ 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  321 PNVASGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYGGA 400
Cdd:TIGR01117 324 PKVMAGCLDIDSSDKIARFIRFCDAFNIPIVTFVDVPGFLPGVNQEYGGIIRHGAKVLYAYSEATVPKVTIITRKAYGGA 403

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  401 YDVMSSKHLLGDTNYAWPTAEIAVMGAKGAVEIIFKghQDVEAAQ----------AEYVEKFANPFPAAVRGFVDDIIQP 470
Cdd:TIGR01117 404 YLAMCSKHLGADQVYAWPTAEIAVMGPAGAANIIFR--KDIKEAKdpaatrkqkiAEYREEFANPYKAAARGYVDDVIEP 481

                         490       500       510
                  ....*....|....*....|....*....|.
gi 568961907  471 SSTRARICCDLEVLASKKVHRPWRKHANIPL 501
Cdd:TIGR01117 482 KQTRPKIVNALAMLESKREKLPPKKHGNIPL 512
PLN02820 PLN02820
3-methylcrotonyl-CoA carboxylase, beta chain
 65-474 1.12e-71

3-methylcrotonyl-CoA carboxylase, beta chain


Pssm-ID: 178415 [Multi-domain]  Cd Length: 569  Bit Score: 238.17  E-value: 1.12e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  65 PGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAG---YADI 141
Cdd:PLN02820 115 PSGGIVTGIGPVHGRLCMFVANDPTVKGGTYYPITVKKHLRAQEIAAQCRLPCIYLVDSGGANLPRQAEVFPDrdhFGRI 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 142 FLRNVTASGV-IPQISLIMGPCAGGAVYSPALTDFTFMVKDTSYLFITGPEVVKSVTNEDVTQEQLGGAKTHTTVSGVAH 220
Cdd:PLN02820 195 FYNQARMSSAgIPQIALVLGSCTAGGAYVPAMADESVIVKGNGTIFLAGPPLVKAATGEEVSAEDLGGADVHCKVSGVSD 274

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 221 RAFDNDVDALCNLREFFNFLPLSSQDP------APIRECHDPsdrLVP--ELDTVVPLESSKAYNMLDIIHAVIDEREFF 292
Cdd:PLN02820 275 HFAQDELHALAIGRNIVKNLHLAAKQGmentlgSKNPEYKEP---LYDvkELRGIVPADHKQSFDVRSVIARIVDGSEFD 351

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 293 EIMPSYAKNIVVGFARMNGRTVGIVGNqpnvaSGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIR 372
Cdd:PLN02820 352 EFKKNYGTTLVTGFARIYGQPVGIIGN-----NGILFTESALKGAHFIELCAQRGIPLLFLQNITGFMVGSRSEASGIAK 426

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 373 HGAKLLYAFAEATVPKITVITRKAYGGAYDVMSSKHLLGDTNYAWPTAEIAVMGAKGAVEIIF---------KGHQ---- 439
Cdd:PLN02820 427 AGAKMVMAVACAKVPKITIIVGGSFGAGNYGMCGRAYSPNFLFMWPNARIGVMGGAQAAGVLAqierenkkrQGIQwske 506

                        410       420       430
                 ....*....|....*....|....*....|....*...
gi 568961907 440 DVEAAQAEYVEKF---ANPFPAAVRGFVDDIIQPSSTR 474
Cdd:PLN02820 507 EEEAFKAKTVEAYereANPYYSTARLWDDGVIDPADTR 544
 
Name Accession Description Interval E-value
MmdA COG4799
Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];
39-499 0e+00

Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];


Pssm-ID: 443827 [Multi-domain]  Cd Length: 508  Bit Score: 732.21  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  39 ERIDNKRHAALLGGGQRRIDAQHKR-----------------------------------FPGDSVVTGRGRINGRLVYV 83
Cdd:COG4799    7 AELRARREEALLGGGEKAIERQHARgkltareridllldpgsflelgalaghrmyddddrVPGDGVVTGIGTVDGRPVVV 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  84 FSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCA 163
Cdd:COG4799   87 VANDFTVKGGSLGPMTAKKILRAQDIALENGLPVIYLVDSGGARLQEGVESFAGYGRIFYRNARSSGGIPQISVIMGPCA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 164 GGAVYSPALTDFTFMVKDTSYLFITGPEVVKSVTNEDVTQEQLGGAKTHTTVSGVAHRAFDNDVDALCNLREFFNFLPLS 243
Cdd:COG4799  167 AGGAYSPALSDFVIMVKGTSQMFLGGPPVVKAATGEEVTAEELGGADVHARVSGVADYLAEDEEEALALARRLLSYLPSN 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 244 SQDPAPIRECHDPsDRLVPELDTVVPLESSKAYNMLDIIHAVIDEREFFEIMPSYAKNIVVGFARMNGRTVGIVGNQPNV 323
Cdd:COG4799  247 NLEDPPRAEPAPP-ARDPEELYGIVPEDPRKPYDMREVIARLVDGGSFFEFKPLYGPNIVTGFARIDGRPVGIVANQPMV 325

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 324 ASGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYGGAYDV 403
Cdd:COG4799  326 LAGVLDIDAADKAARFIRLCDAFNIPLVFLVDVPGFMVGTEQERGGIIRHGAKLLYAVAEATVPKITVILRKAYGAGYYA 405

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 404 MSSKHLLGDTNYAWPTAEIAVMGAKGAVEIIFK----GHQDVEAAQAEYVEKF---ANPFPAAVRGFVDDIIQPSSTRAR 476
Cdd:COG4799  406 MCGKALGPDFLFAWPTAEIAVMGGEGAANVLYRrelaAAEDPEALRAELIAEYeeqANPYYAAARGWIDDVIDPRDTRRV 485

                        490       500
                 ....*....|....*....|...
gi 568961907 477 ICCDLEVLASKKVHRPWRKHANI 499
Cdd:COG4799  486 LARALEAAANKPEERPPKKHGVI 508
Carboxyl_trans pfam01039
Carboxyl transferase domain; All of the members in this family are biotin dependent ...
 62-499 0e+00

Carboxyl transferase domain; All of the members in this family are biotin dependent carboxylases. The carboxyl transferase domain carries out the following reaction; transcarboxylation from biotin to an acceptor molecule. There are two recognized types of carboxyl transferase. One of them uses acyl-CoA and the other uses 2-oxoacid as the acceptor molecule of carbon dioxide. All of the members in this family utilize acyl-CoA as the acceptor molecule.


Pssm-ID: 426008 [Multi-domain]  Cd Length: 491  Bit Score: 655.10  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907   62 KRFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAGYADI 141
Cdd:pfam01039  40 KRIPRDGVVTGSGAVIGRAVEVVAQDFTVFGGSLGPAKGEKILRAMEIAIKTGLPLIGINDSGGARIQEGVENLRGSGKI 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  142 FLRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFMVKDTSYLFITGPEVVKSVTNEDVTQEQLGGAKTHTTVSGVAHR 221
Cdd:pfam01039 120 FGRNSLASGVIPQISLIMGPCAGGGAYLPALGDFVIMVEGTSPMFLTGPPVIKKVTGEEVTSEELGGATQHMTISGVSHL 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  222 AFDNDVDALCNLREFFNFLPL---SSQDPAPIRECHDPSDRLVPeLDTVVPLESSKAYNMLDIIHAVIDEREFFEIMPSY 298
Cdd:pfam01039 200 TALDDEDALELIRKWLSYLPKpapNNREPVPIVPTKDPPDRDAP-LVSIVPDDPKKPYDVREVIAGIVDEGEFFEIKPGY 278

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  299 AKNIVVGFARMNGRTVGIVGNQPNVASGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLL 378
Cdd:pfam01039 279 AKTVVTGFARLGGIPVGVVANQPRVGAGVLFPDSADKAARFIRDCDAFNLPLVILADVPGFLPGQRQEYGGILKHGAKLL 358

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  379 YAFAEATVPKITVITRKAYGGAYDVMSSKHLLGDTNYAWPTAEIAVMGAKGAVEIIF--------KGHQDVEAA----QA 446
Cdd:pfam01039 359 YALAEATVPKITVIPRKAYGGAYVVMDSKINGADINFAWPTARIAVMGPEGAVEIKFrkekaaaeMRGKDLAATrkqkIA 438

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 568961907  447 EYVEKFANPFPAAVRGFVDDIIQPSSTRARICCDLEVLASKKVHRPWRKHANI 499
Cdd:pfam01039 439 EYEEELSPPYVAAARGFADAVIDPGRTRAKLVIALAALWTKPRFFPWRKHGNI 491
mmdA TIGR01117
methylmalonyl-CoA decarboxylase alpha subunit; This model describes methymalonyl-CoA ...
 39-501 0e+00

methylmalonyl-CoA decarboxylase alpha subunit; This model describes methymalonyl-CoA decarboxylase aplha subunit in archaea and bacteria. Metylmalonyl-CoA decarboxylase Na+ pump is a representative of a class of Na+ transport decarboxylases that couples the energy derived by decarboxylation of carboxylic acid substrates to drive the extrusion of Na+ ion across the membrane. [Energy metabolism, ATP-proton motive force interconversion, Energy metabolism, Fermentation, Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130187  Cd Length: 512  Bit Score: 624.55  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907   39 ERIDNKRHAALLGGGQRRIDAQH--------------------------------------KRFPGDSVVTGRGRINGRL 80
Cdd:TIGR01117   4 EELHEKKEKIKQGGGEKRIEKQHaqgkmtarerlallfdpgsfveidqfvkhrctnfgmdkKELPAEGVVTGYGTIDGRL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907   81 VYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMG 160
Cdd:TIGR01117  84 VYAFAQDFTVMGGSLGEMHAAKIVKIMDLAMKMGAPVVGLNDSGGARIQEAVDALKGYGDIFYRNTIASGVVPQISAIMG 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  161 PCAGGAVYSPALTDFTFMVKDTSYLFITGPEVVKSVTNEDVTQEQLGGAKTHTTVSGVAHRAFDNDVDALCNLREFFNFL 240
Cdd:TIGR01117 164 PCAGGAVYSPALTDFIYMVDNTSQMFITGPQVIKTVTGEEVTAEQLGGAMAHNSVSGVAHFIAEDDDDCIMLIRRLLSFL 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  241 PLSSQDPAPIRECHDPSDRLVPELDTVVPLESSKAYNMLDIIHAVIDEREFFEIMPSYAKNIVVGFARMNGRTVGIVGNQ 320
Cdd:TIGR01117 244 PSNNMEKAPLVKTGDDPTRETPELYDLLPDNPNKPYDMRDVITAIVDNGDYLEVQPYYAPNIITCFARINGQSVGIIANQ 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  321 PNVASGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYGGA 400
Cdd:TIGR01117 324 PKVMAGCLDIDSSDKIARFIRFCDAFNIPIVTFVDVPGFLPGVNQEYGGIIRHGAKVLYAYSEATVPKVTIITRKAYGGA 403

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  401 YDVMSSKHLLGDTNYAWPTAEIAVMGAKGAVEIIFKghQDVEAAQ----------AEYVEKFANPFPAAVRGFVDDIIQP 470
Cdd:TIGR01117 404 YLAMCSKHLGADQVYAWPTAEIAVMGPAGAANIIFR--KDIKEAKdpaatrkqkiAEYREEFANPYKAAARGYVDDVIEP 481

                         490       500       510
                  ....*....|....*....|....*....|.
gi 568961907  471 SSTRARICCDLEVLASKKVHRPWRKHANIPL 501
Cdd:TIGR01117 482 KQTRPKIVNALAMLESKREKLPPKKHGNIPL 512
PLN02820 PLN02820
3-methylcrotonyl-CoA carboxylase, beta chain
 65-474 1.12e-71

3-methylcrotonyl-CoA carboxylase, beta chain


Pssm-ID: 178415 [Multi-domain]  Cd Length: 569  Bit Score: 238.17  E-value: 1.12e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  65 PGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAG---YADI 141
Cdd:PLN02820 115 PSGGIVTGIGPVHGRLCMFVANDPTVKGGTYYPITVKKHLRAQEIAAQCRLPCIYLVDSGGANLPRQAEVFPDrdhFGRI 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 142 FLRNVTASGV-IPQISLIMGPCAGGAVYSPALTDFTFMVKDTSYLFITGPEVVKSVTNEDVTQEQLGGAKTHTTVSGVAH 220
Cdd:PLN02820 195 FYNQARMSSAgIPQIALVLGSCTAGGAYVPAMADESVIVKGNGTIFLAGPPLVKAATGEEVSAEDLGGADVHCKVSGVSD 274

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 221 RAFDNDVDALCNLREFFNFLPLSSQDP------APIRECHDPsdrLVP--ELDTVVPLESSKAYNMLDIIHAVIDEREFF 292
Cdd:PLN02820 275 HFAQDELHALAIGRNIVKNLHLAAKQGmentlgSKNPEYKEP---LYDvkELRGIVPADHKQSFDVRSVIARIVDGSEFD 351

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 293 EIMPSYAKNIVVGFARMNGRTVGIVGNqpnvaSGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIR 372
Cdd:PLN02820 352 EFKKNYGTTLVTGFARIYGQPVGIIGN-----NGILFTESALKGAHFIELCAQRGIPLLFLQNITGFMVGSRSEASGIAK 426

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 373 HGAKLLYAFAEATVPKITVITRKAYGGAYDVMSSKHLLGDTNYAWPTAEIAVMGAKGAVEIIF---------KGHQ---- 439
Cdd:PLN02820 427 AGAKMVMAVACAKVPKITIIVGGSFGAGNYGMCGRAYSPNFLFMWPNARIGVMGGAQAAGVLAqierenkkrQGIQwske 506

                        410       420       430
                 ....*....|....*....|....*....|....*...
gi 568961907 440 DVEAAQAEYVEKF---ANPFPAAVRGFVDDIIQPSSTR 474
Cdd:PLN02820 507 EEEAFKAKTVEAYereANPYYSTARLWDDGVIDPADTR 544
AccD COG0777
Acetyl-CoA carboxylase beta subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase ...
 67-135 8.62e-13

Acetyl-CoA carboxylase beta subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase beta subunit is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440540 [Multi-domain]  Cd Length: 280  Bit Score: 68.55  E-value: 8.62e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568961907  67 DSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESL 135
Cdd:COG0777  107 DAVVTGTGTINGIPVVVAVMDFSFMGGSMGSVVGEKITRAIERAIEKKLPLIIFSASGGARMQEGILSL 175
PRK07189 PRK07189
malonate decarboxylase subunit beta; Reviewed
 67-193 2.57e-10

malonate decarboxylase subunit beta; Reviewed


Pssm-ID: 235954  Cd Length: 301  Bit Score: 61.46  E-value: 2.57e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907  67 DSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVG-----APVIGLNDSGGARIQEGVESLAGYADI 141
Cdd:PRK07189  56 DGVVVGKGTLDGRPVVVAAQEGRFMGGSVGEVHGAKLAGALELAAEDNrngipTAVLLLFETGGVRLQEANAGLAAIAEI 135

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 568961907 142 FLRNVTASGVIPQISLIMGP--CAGGAVYSPALTDfTFMVKDTSYLFITGPEVV 193
Cdd:PRK07189 136 MRAIVDLRAAVPVIGLIGGRvgCFGGMGIAAALCS-YLIVSEEGRLGLSGPEVI 188
PRK05724 PRK05724
acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated
 279-400 1.32e-08

acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated


Pssm-ID: 235580 [Multi-domain]  Cd Length: 319  Bit Score: 56.30  E-value: 1.32e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 279 LDIIHAVIDEreFFEIM--PSYA--KNIVVGFARMNGRTVGIVGNQpnvaSGClDINSSV-------------KGARFVR 341
Cdd:PRK05724  73 LDYIELLFTD--FTELHgdRAFAddKAIVGGLARLNGRPVMVIGHQ----KGR-DTKEKIrrnfgmprpegyrKALRLMK 145

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568961907 342 FCDAFNIPLITFVDVPGFLPG-TAQEYG---GIirhgAKLLYAFAEATVPKI-TVITRKAYGGA 400
Cdd:PRK05724 146 MAEKFGLPIITFIDTPGAYPGiGAEERGqseAI----ARNLREMARLKVPIIcTVIGEGGSGGA 205
accD CHL00174
acetyl-CoA carboxylase beta subunit; Reviewed
 67-141 2.60e-07

acetyl-CoA carboxylase beta subunit; Reviewed


Pssm-ID: 214384 [Multi-domain]  Cd Length: 296  Bit Score: 52.21  E-value: 2.60e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568961907  67 DSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAGYADI 141
Cdd:CHL00174 121 DAVQTGIGQLNGIPVALGVMDFQFMGGSMGSVVGEKITRLIEYATNESLPLIIVCASGGARMQEGSLSLMQMAKI 195
AccA COG0825
Acetyl-CoA carboxylase alpha subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase ...
 279-393 9.62e-07

Acetyl-CoA carboxylase alpha subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase alpha subunit is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440587 [Multi-domain]  Cd Length: 315  Bit Score: 50.42  E-value: 9.62e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 279 LDIIHAVIDEreFFEIM--PSYA--KNIVVGFARMNGRTVGIVGNQpnvasgcldinssvKGA----------------- 337
Cdd:COG0825   70 LDYIEAIFTD--FIELHgdRAFGddPAIVGGLARFDGRPVMVIGHQ--------------KGRdtkerikrnfgmphpeg 133

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568961907 338 -----RFVRFCDAFNIPLITFVDVPGFLPG-TAQEYG---GIirhgAKLLYAFAEATVPKITVIT 393
Cdd:COG0825  134 yrkalRLMKLAEKFGLPIITFIDTPGAYPGiGAEERGqseAI----ARNLREMARLKVPIISVVI 194
PLN03230 PLN03230
acetyl-coenzyme A carboxylase carboxyl transferase; Provisional
 302-400 3.74e-04

acetyl-coenzyme A carboxylase carboxyl transferase; Provisional


Pssm-ID: 178769 [Multi-domain]  Cd Length: 431  Bit Score: 43.01  E-value: 3.74e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 302 IVVGFARMNGRTVGIVGNQPNVAS--------GCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPG-TAQEYGgiir 372
Cdd:PLN03230 168 IVCGIGSMEGMSFMFIGHQKGRNTkeniyrnfAMPQPNGYRKALRFMRHAEKFGFPILTFVDTPGAYAGiKAEELG---- 243

                         90       100       110
                 ....*....|....*....|....*....|..
gi 568961907 373 HGAKLLYAFAEA---TVPKI-TVITRKAYGGA 400
Cdd:PLN03230 244 QGEAIAFNLREMfglRVPIIaTVIGEGGSGGA 275
accA CHL00198
acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional
 302-400 5.41e-04

acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional


Pssm-ID: 214393 [Multi-domain]  Cd Length: 322  Bit Score: 42.11  E-value: 5.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 302 IVVGFARMNGRTVGIVGNQ------PNVAS--GCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRH 373
Cdd:CHL00198 101 LVGGIGKINGRTIVFLGHQrgrntkENVLRnfGMPSPGGYRKALRLMKHANKFGLPILTFIDTPGAWAGVKAEKLGQGEA 180

                         90       100
                 ....*....|....*....|....*...
gi 568961907 374 GAKLLYAFAEATVPKI-TVITRKAYGGA 400
Cdd:CHL00198 181 IAVNLREMFSFEVPIIcTIIGEGGSGGA 208
PRK12319 PRK12319
acetyl-CoA carboxylase subunit alpha; Provisional
 302-445 6.94e-03

acetyl-CoA carboxylase subunit alpha; Provisional


Pssm-ID: 183435 [Multi-domain]  Cd Length: 256  Bit Score: 38.22  E-value: 6.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568961907 302 IVVGFARMNGRTVGIVGNQP------NVAS--GCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRH 373
Cdd:PRK12319  45 VVGGIGYLAGQPVTVVGIQKgknlqdNLKRnfGQPHPEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEA 124

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568961907 374 GAKLLYAFAEATVPKITVITRKAYGG---AYDVMSSKHLLGDTNYawptaeiAVMGAKGAVEIIFK-GHQDVEAAQ 445
Cdd:PRK12319 125 IARNLMEMSDLKVPIIAIIIGEGGSGgalALAVADQVWMLENTMY-------AVLSPEGFASILWKdGSRATEAAE 193
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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