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Conserved domains on  [gi|568923910|ref|XP_006502075|]
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bolA-like protein 1 isoform X1 [Mus musculus]

Protein Classification

BolA family transcriptional regulator( domain architecture ID 10000955)

BolA family transcriptional regulator is a stress-responsive transcriptional regulator; may also participate in iron metabolism

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BolA COG0271
DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and ...
 31-116 1.67e-40

DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and biofilm formation [Transcription, Signal transduction mechanisms];


:

Pssm-ID: 440041  Cd Length: 90  Bit Score: 130.31  E-value: 1.67e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568923910  31 PVEAAIRAKLEQALSPEVLELRNESGGHAVPAG--SETHFRVAVVSSRFEGMSPLQRHRLVHEALSEELAGPVHALAIQA 108
Cdd:COG0271    2 SRQERIEEKLTAALAPEHLEVIDESHLHAGHAGagGESHFKVVIVSDAFAGKSRVARHRLVYAALADELAGGIHALAIHA 81


                 ....*...
gi 568923910 109 KTPAQWRE 116
Cdd:COG0271   82 YTPEEWQA 89
 
Name Accession Description Interval E-value
BolA COG0271
DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and ...
 31-116 1.67e-40

DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and biofilm formation [Transcription, Signal transduction mechanisms];


Pssm-ID: 440041  Cd Length: 90  Bit Score: 130.31  E-value: 1.67e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568923910  31 PVEAAIRAKLEQALSPEVLELRNESGGHAVPAG--SETHFRVAVVSSRFEGMSPLQRHRLVHEALSEELAGPVHALAIQA 108
Cdd:COG0271    2 SRQERIEEKLTAALAPEHLEVIDESHLHAGHAGagGESHFKVVIVSDAFAGKSRVARHRLVYAALADELAGGIHALAIHA 81


                 ....*...
gi 568923910 109 KTPAQWRE 116
Cdd:COG0271   82 YTPEEWQA 89
BolA pfam01722
BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various ...
 40-113 1.71e-36

BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various homologs. In E. coli over expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division. The expression of BolA is growth rate regulated and is induced during the transition into the the stationary phase. BolA is also induced by stress during early stages of growth and may have a general role in stress response. It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5.


Pssm-ID: 460305  Cd Length: 75  Bit Score: 119.48  E-value: 1.71e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568923910   40 LEQALSPEVLELRNESGGHAVPA-GSETHFRVAVVSSRFEGMSPLQRHRLVHEALSEELAGPVHALAIQAKTPAQ 113
Cdd:pfam01722   1 LTEALAPTHLEVEDESHKHAGHAgGGETHFKVVIVSDAFEGKSLVARHRLVYDALADELAGGIHALSIKTYTPEE 75
PRK11628 PRK11628
transcriptional regulator BolA; Provisional
 36-129 5.26e-27

transcriptional regulator BolA; Provisional


Pssm-ID: 183243  Cd Length: 105  Bit Score: 96.77  E-value: 5.26e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568923910  36 IRAKLEQALSPEVLELRNESGGHAVPAGSETHFRVAVVSSRFEGMSPLQRHRLVHEALSEELAGPVHALAIQAKTPAQWR 115
Cdd:PRK11628   7 IEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKEWE 86

                         90
                 ....*....|....*
gi 568923910 116 ENPQ-LDISPPCLGG 129
Cdd:PRK11628  87 GLQDtVFASPPCRGA 101
 
Name Accession Description Interval E-value
BolA COG0271
DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and ...
 31-116 1.67e-40

DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and biofilm formation [Transcription, Signal transduction mechanisms];


Pssm-ID: 440041  Cd Length: 90  Bit Score: 130.31  E-value: 1.67e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568923910  31 PVEAAIRAKLEQALSPEVLELRNESGGHAVPAG--SETHFRVAVVSSRFEGMSPLQRHRLVHEALSEELAGPVHALAIQA 108
Cdd:COG0271    2 SRQERIEEKLTAALAPEHLEVIDESHLHAGHAGagGESHFKVVIVSDAFAGKSRVARHRLVYAALADELAGGIHALAIHA 81


                 ....*...
gi 568923910 109 KTPAQWRE 116
Cdd:COG0271   82 YTPEEWQA 89
BolA pfam01722
BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various ...
 40-113 1.71e-36

BolA-like protein; This family consist of the morphoprotein BolA from E. coli and its various homologs. In E. coli over expression of this protein causes round morphology and may be involved in switching the cell between elongation and septation systems during cell division. The expression of BolA is growth rate regulated and is induced during the transition into the the stationary phase. BolA is also induced by stress during early stages of growth and may have a general role in stress response. It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5.


Pssm-ID: 460305  Cd Length: 75  Bit Score: 119.48  E-value: 1.71e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568923910   40 LEQALSPEVLELRNESGGHAVPA-GSETHFRVAVVSSRFEGMSPLQRHRLVHEALSEELAGPVHALAIQAKTPAQ 113
Cdd:pfam01722   1 LTEALAPTHLEVEDESHKHAGHAgGGETHFKVVIVSDAFEGKSLVARHRLVYDALADELAGGIHALSIKTYTPEE 75
PRK11628 PRK11628
transcriptional regulator BolA; Provisional
 36-129 5.26e-27

transcriptional regulator BolA; Provisional


Pssm-ID: 183243  Cd Length: 105  Bit Score: 96.77  E-value: 5.26e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568923910  36 IRAKLEQALSPEVLELRNESGGHAVPAGSETHFRVAVVSSRFEGMSPLQRHRLVHEALSEELAGPVHALAIQAKTPAQWR 115
Cdd:PRK11628   7 IEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKEWE 86

                         90
                 ....*....|....*
gi 568923910 116 ENPQ-LDISPPCLGG 129
Cdd:PRK11628  87 GLQDtVFASPPCRGA 101
IbaG COG5007
Acid stress protein IbaG/YrbA, BolA-like family [Signal transduction mechanisms];
34-120 3.58e-20

Acid stress protein IbaG/YrbA, BolA-like family [Signal transduction mechanisms];


Pssm-ID: 444031  Cd Length: 81  Bit Score: 78.27  E-value: 3.58e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568923910  34 AAIRAKLEQALSPEVLELrnESGGHavpagsetHFRVAVVSSRFEGMSPLQRHRLVHEALSEELA-GPVHALAIQAKTPA 112
Cdd:COG5007    4 EEIKQLIEAGLPCAEVEV--EGDGS--------HFEAIVVSDAFEGLSRVKRQQLVYAPLGDYIAsGEIHALSIKTYTPE 73


                 ....*...
gi 568923910 113 QWRENPQL 120
Cdd:COG5007   74 EWAAQRKL 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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