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Conserved domains on  [gi|530387976|ref|XP_005273659|]
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FHF complex subunit HOOK-interacting protein 2B isoform X2 [Homo sapiens]

Protein Classification

FAM160 family protein( domain architecture ID 10563057)

FAM160 family protein such as human FAM160A1/2 (Family with sequence similarity 160 Member A1/2) and FAM160B1/2 proteins, each containing a conserved retinoic acid induced 16 (RAI16)-like domain with unknown biological function

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RAI16-like pfam10257
Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a ...
 79-476 1.02e-148

Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a family of proteins described as retinoic acid-induced protein 16-like proteins. The exact function is not known. The proteins are found from worms to humans.


:

Pssm-ID: 370927  Cd Length: 357  Bit Score: 434.06  E-value: 1.02e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530387976   79 CLEYLLQHKILETLCTLGKAEYPPGMRQQVFQFFSKVLAQVQHPLLHYLSVHRPVQKLLRLGGTASGSVTEKEEVQFTTV 158
Cdd:pfam10257   1 CLEYLLQHKILETLCTLGKADYPPGMKQEVLKFYNKLLSHERQPLLHHINVHRPLQKLLRSCGEPVGSDVEKELVQLLFG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530387976  159 LCSKIQQDPELLAYILEGKKIvgrkkacgeptalpkdttshgdkdcshdgaparpqldgescGAQALNSHMPAETEELDG 238
Cdd:pfam10257  81 LCVKLRQDPSLLNFFFENKSD-----------------------------------------QQRAELLVNPSVEFAGAT 119

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530387976  239 GTTESNLITSLLGLCQSKkSRVALKAQENLLLLVSMAS--PAAATYLVQSSACCPAIVRHLCQLYRSMPVFLDpadIATL 316
Cdd:pfam10257 120 GKEDFNLFSLLLPLVHRE-GRLGVFAREGLLLLMSLASrsPTLATYLIESSDLCPLLATGLGALYSLLPTSLP---APTI 195

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530387976  317 EGISWRL--PSAPSDEASFPGKEALAAFLGWFDYCDHLITEAHTVVADALAKAVAENFFVETLQPQLLHVSEQSILTSTA 394
Cdd:pfam10257 196 SSIDWRLdhSIAPEDLATFPGKRALDSFLSWLDFCNDLIQVAHSEVADALLDAIYEGFLVPVLYPSLLQTSEGSILAVTA 275

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530387976  395 LLTAMLRQLRSPALLREAVAFLLGTDRQPEAPGDNPHTLYAHLIGHCDHLSDEISITTLRLFEELLQKPHEGIIHSLVLR 474
Cdd:pfam10257 276 YLDRILRSITSPALLQEFLSFLLGEEKSPETSDDDGHPLRDTLIERCNHLSDELSIVTLRLFETLLQLPCEDILLDLVLR 355


                  ..
gi 530387976  475 NL 476
Cdd:pfam10257 356 NL 357
 
Name Accession Description Interval E-value
RAI16-like pfam10257
Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a ...
 79-476 1.02e-148

Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a family of proteins described as retinoic acid-induced protein 16-like proteins. The exact function is not known. The proteins are found from worms to humans.


Pssm-ID: 370927  Cd Length: 357  Bit Score: 434.06  E-value: 1.02e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530387976   79 CLEYLLQHKILETLCTLGKAEYPPGMRQQVFQFFSKVLAQVQHPLLHYLSVHRPVQKLLRLGGTASGSVTEKEEVQFTTV 158
Cdd:pfam10257   1 CLEYLLQHKILETLCTLGKADYPPGMKQEVLKFYNKLLSHERQPLLHHINVHRPLQKLLRSCGEPVGSDVEKELVQLLFG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530387976  159 LCSKIQQDPELLAYILEGKKIvgrkkacgeptalpkdttshgdkdcshdgaparpqldgescGAQALNSHMPAETEELDG 238
Cdd:pfam10257  81 LCVKLRQDPSLLNFFFENKSD-----------------------------------------QQRAELLVNPSVEFAGAT 119

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530387976  239 GTTESNLITSLLGLCQSKkSRVALKAQENLLLLVSMAS--PAAATYLVQSSACCPAIVRHLCQLYRSMPVFLDpadIATL 316
Cdd:pfam10257 120 GKEDFNLFSLLLPLVHRE-GRLGVFAREGLLLLMSLASrsPTLATYLIESSDLCPLLATGLGALYSLLPTSLP---APTI 195

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530387976  317 EGISWRL--PSAPSDEASFPGKEALAAFLGWFDYCDHLITEAHTVVADALAKAVAENFFVETLQPQLLHVSEQSILTSTA 394
Cdd:pfam10257 196 SSIDWRLdhSIAPEDLATFPGKRALDSFLSWLDFCNDLIQVAHSEVADALLDAIYEGFLVPVLYPSLLQTSEGSILAVTA 275

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530387976  395 LLTAMLRQLRSPALLREAVAFLLGTDRQPEAPGDNPHTLYAHLIGHCDHLSDEISITTLRLFEELLQKPHEGIIHSLVLR 474
Cdd:pfam10257 276 YLDRILRSITSPALLQEFLSFLLGEEKSPETSDDDGHPLRDTLIERCNHLSDELSIVTLRLFETLLQLPCEDILLDLVLR 355


                  ..
gi 530387976  475 NL 476
Cdd:pfam10257 356 NL 357
 
Name Accession Description Interval E-value
RAI16-like pfam10257
Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a ...
 79-476 1.02e-148

Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a family of proteins described as retinoic acid-induced protein 16-like proteins. The exact function is not known. The proteins are found from worms to humans.


Pssm-ID: 370927  Cd Length: 357  Bit Score: 434.06  E-value: 1.02e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530387976   79 CLEYLLQHKILETLCTLGKAEYPPGMRQQVFQFFSKVLAQVQHPLLHYLSVHRPVQKLLRLGGTASGSVTEKEEVQFTTV 158
Cdd:pfam10257   1 CLEYLLQHKILETLCTLGKADYPPGMKQEVLKFYNKLLSHERQPLLHHINVHRPLQKLLRSCGEPVGSDVEKELVQLLFG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530387976  159 LCSKIQQDPELLAYILEGKKIvgrkkacgeptalpkdttshgdkdcshdgaparpqldgescGAQALNSHMPAETEELDG 238
Cdd:pfam10257  81 LCVKLRQDPSLLNFFFENKSD-----------------------------------------QQRAELLVNPSVEFAGAT 119

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530387976  239 GTTESNLITSLLGLCQSKkSRVALKAQENLLLLVSMAS--PAAATYLVQSSACCPAIVRHLCQLYRSMPVFLDpadIATL 316
Cdd:pfam10257 120 GKEDFNLFSLLLPLVHRE-GRLGVFAREGLLLLMSLASrsPTLATYLIESSDLCPLLATGLGALYSLLPTSLP---APTI 195

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530387976  317 EGISWRL--PSAPSDEASFPGKEALAAFLGWFDYCDHLITEAHTVVADALAKAVAENFFVETLQPQLLHVSEQSILTSTA 394
Cdd:pfam10257 196 SSIDWRLdhSIAPEDLATFPGKRALDSFLSWLDFCNDLIQVAHSEVADALLDAIYEGFLVPVLYPSLLQTSEGSILAVTA 275

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530387976  395 LLTAMLRQLRSPALLREAVAFLLGTDRQPEAPGDNPHTLYAHLIGHCDHLSDEISITTLRLFEELLQKPHEGIIHSLVLR 474
Cdd:pfam10257 276 YLDRILRSITSPALLQEFLSFLLGEEKSPETSDDDGHPLRDTLIERCNHLSDELSIVTLRLFETLLQLPCEDILLDLVLR 355


                  ..
gi 530387976  475 NL 476
Cdd:pfam10257 356 NL 357
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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