presenilin-associated rhomboid-like protein, mitochondrial isoform X1 [Homo sapiens]
rhomboid family intramembrane serine protease( domain architecture ID 10483871)
rhomboid family intramembrane serine protease is a membrane-bound protein that catalyzes regulated intramembrane proteolysis, resulting in the release of functional polypeptides from their membrane anchor
List of domain hits
Name | Accession | Description | Interval | E-value | |||
Rhomboid | pfam01694 | Rhomboid family; This family contains integral membrane proteins that are related to ... |
209-350 | 2.25e-28 | |||
Rhomboid family; This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite. : Pssm-ID: 426384 Cd Length: 147 Bit Score: 108.46 E-value: 2.25e-28
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Name | Accession | Description | Interval | E-value | ||||
Rhomboid | pfam01694 | Rhomboid family; This family contains integral membrane proteins that are related to ... |
209-350 | 2.25e-28 | ||||
Rhomboid family; This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite. Pssm-ID: 426384 Cd Length: 147 Bit Score: 108.46 E-value: 2.25e-28
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GlpG | COG0705 | Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein ... |
169-351 | 6.49e-27 | ||||
Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 440469 [Multi-domain] Cd Length: 189 Bit Score: 105.71 E-value: 6.49e-27
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Name | Accession | Description | Interval | E-value | ||||
Rhomboid | pfam01694 | Rhomboid family; This family contains integral membrane proteins that are related to ... |
209-350 | 2.25e-28 | ||||
Rhomboid family; This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite. Pssm-ID: 426384 Cd Length: 147 Bit Score: 108.46 E-value: 2.25e-28
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GlpG | COG0705 | Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein ... |
169-351 | 6.49e-27 | ||||
Membrane-associated serine protease, rhomboid family [Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 440469 [Multi-domain] Cd Length: 189 Bit Score: 105.71 E-value: 6.49e-27
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Blast search parameters | ||||
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