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Conserved domains on  [gi|45827767|ref|NP_995584|]
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UDP-glucuronosyltransferase 1-6 isoform 2 [Homo sapiens]

Protein Classification

UDP-glycosyltransferase family protein( domain architecture ID 11989770)

UDP-glycosyltransferase family protein similar to UDP-glucuronosyltransferase (UDPGT), which is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
1-256 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


:

Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 573.20  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767     1 MPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANN 80
Cdd:pfam00201 244 LPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPSTLGNN 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767    81 TILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALK 160
Cdd:pfam00201 324 TRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLLNALK 403

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   161 AVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFK 240
Cdd:pfam00201 404 EVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAFITFK 483

                         250
                  ....*....|....*.
gi 45827767   241 CCAYGYRKCLGKKGRV 256
Cdd:pfam00201 484 CCLFGYRKFVGKKKRV 499
 
Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
1-256 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 573.20  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767     1 MPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANN 80
Cdd:pfam00201 244 LPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPSTLGNN 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767    81 TILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALK 160
Cdd:pfam00201 324 TRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLLNALK 403

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   161 AVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFK 240
Cdd:pfam00201 404 EVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAFITFK 483

                         250
                  ....*....|....*.
gi 45827767   241 CCAYGYRKCLGKKGRV 256
Cdd:pfam00201 484 CCLFGYRKFVGKKKRV 499
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 1-178 5.91e-59

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 192.38  E-value: 5.91e-59
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   1 MPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPS---NL 77
Cdd:cd03784 208 RLPSVLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVRDLPEELLELIAEALASLGQRFLWVVGPDPLGgleRL 287

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767  78 ANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLEN 157
Cdd:cd03784 288 PDNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELTAEELAK 367

                       170       180
                ....*....|....*....|.
gi 45827767 158 ALKAVINDKSYKENIMRLSSL 178
Cdd:cd03784 368 AVREVLEDESYRRAAELLAEL 388
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 2-239 1.25e-43

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 154.34  E-value: 1.25e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767    2 PNMVFIGGI--NCKKRKDLSQEFEAYINASGEhGIVVFSLGSMVseipEKKAMA------IADALGKIPQTVLWRYTGT- 72
Cdd:PHA03392 265 PSVQYLGGLhlHKKPPQPLDDYLEEFLNNSTN-GVVYVSFGSSI----DTNDMDneflqmLLRTFKKLPYNVLWKYDGEv 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   73 RPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTS 152
Cdd:PHA03392 340 EAINLPANVLTQKWFPQRAVLKHKNVKAFVTQGGVQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGRALDTVTVSA 419

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767  153 EDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKG-APHLRPAAHDLTWYQYhsldVIGFLLAVV 231
Cdd:PHA03392 420 AQLVLAIVDVIENPKYRKNLKELRHLIRHQPMTPLHKAIWYTEHVIRNKHgNTSLKTKAANVSYSDY----FMSYILVPL 495


                 ....*...
gi 45827767  232 LTVAFITF 239
Cdd:PHA03392 496 VTFTVMNH 503
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
2-176 2.09e-32

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 119.58  E-value: 2.09e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   2 PNMVFIGGInckkRKDLSQEFEAYINASGEHGIVVFSLGSMVSEiPEKKAMAIADALGKIPQTVLWRYTGTRPSNLAN-- 79
Cdd:COG1819  94 ANVRFVGPL----LPDGPAELPPWLEEDAGRPLVYVTLGTSAND-RADLLRAVLEALADLGVRVVVTTGGLDPAELGPlp 168

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767  80 -NTILVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENA 158
Cdd:COG1819 169 dNVRVVDYVPQDALLPR--ADAVVHHGGAGTTAEALRAGVPQVVVPFGGDQPLNAARVERLGAGLALPPRRLTAEALRAA 246

                       170
                ....*....|....*...
gi 45827767 159 LKAVINDKSYKENIMRLS 176
Cdd:COG1819 247 LRRLLADPSYRERAARLA 264
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 32-175 2.67e-20

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 88.97  E-value: 2.67e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767    32 HGIVVFSLGSMVSEIPEKKAMAIaDALGKIP-QTVLWRYTGTRPSNLAN---NTILVKWLPQNDLLGHpmTRAFITHAGS 107
Cdd:TIGR01426 225 RPVVLISLGTVFNNQPSFYRTCV-EAFRDLDwHVVLSVGRGVDPADLGElppNVEVRQWVPQLEILKK--ADAFITHGGM 301

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 45827767   108 HGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRL 175
Cdd:TIGR01426 302 NSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEKLREAVLAVLSDPRYAERLRKM 369
 
Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
1-256 0e+00

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 573.20  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767     1 MPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANN 80
Cdd:pfam00201 244 LPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDGTKPSTLGNN 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767    81 TILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALK 160
Cdd:pfam00201 324 TRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMTSEDLLNALK 403

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   161 AVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFK 240
Cdd:pfam00201 404 EVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACVATVAFITFK 483

                         250
                  ....*....|....*.
gi 45827767   241 CCAYGYRKCLGKKGRV 256
Cdd:pfam00201 484 CCLFGYRKFVGKKKRV 499
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 1-178 5.91e-59

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 192.38  E-value: 5.91e-59
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   1 MPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPS---NL 77
Cdd:cd03784 208 RLPSVLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVRDLPEELLELIAEALASLGQRFLWVVGPDPLGgleRL 287

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767  78 ANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLEN 157
Cdd:cd03784 288 PDNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELTAEELAK 367

                       170       180
                ....*....|....*....|.
gi 45827767 158 ALKAVINDKSYKENIMRLSSL 178
Cdd:cd03784 368 AVREVLEDESYRRAAELLAEL 388
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 2-239 1.25e-43

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 154.34  E-value: 1.25e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767    2 PNMVFIGGI--NCKKRKDLSQEFEAYINASGEhGIVVFSLGSMVseipEKKAMA------IADALGKIPQTVLWRYTGT- 72
Cdd:PHA03392 265 PSVQYLGGLhlHKKPPQPLDDYLEEFLNNSTN-GVVYVSFGSSI----DTNDMDneflqmLLRTFKKLPYNVLWKYDGEv 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   73 RPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTS 152
Cdd:PHA03392 340 EAINLPANVLTQKWFPQRAVLKHKNVKAFVTQGGVQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGRALDTVTVSA 419

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767  153 EDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKG-APHLRPAAHDLTWYQYhsldVIGFLLAVV 231
Cdd:PHA03392 420 AQLVLAIVDVIENPKYRKNLKELRHLIRHQPMTPLHKAIWYTEHVIRNKHgNTSLKTKAANVSYSDY----FMSYILVPL 495


                 ....*...
gi 45827767  232 LTVAFITF 239
Cdd:PHA03392 496 VTFTVMNH 503
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
2-176 2.09e-32

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 119.58  E-value: 2.09e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   2 PNMVFIGGInckkRKDLSQEFEAYINASGEHGIVVFSLGSMVSEiPEKKAMAIADALGKIPQTVLWRYTGTRPSNLAN-- 79
Cdd:COG1819  94 ANVRFVGPL----LPDGPAELPPWLEEDAGRPLVYVTLGTSAND-RADLLRAVLEALADLGVRVVVTTGGLDPAELGPlp 168

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767  80 -NTILVKWLPQNDLLGHpmTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENA 158
Cdd:COG1819 169 dNVRVVDYVPQDALLPR--ADAVVHHGGAGTTAEALRAGVPQVVVPFGGDQPLNAARVERLGAGLALPPRRLTAEALRAA 246

                       170
                ....*....|....*...
gi 45827767 159 LKAVINDKSYKENIMRLS 176
Cdd:COG1819 247 LRRLLADPSYRERAARLA 264
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 32-175 2.67e-20

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 88.97  E-value: 2.67e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767    32 HGIVVFSLGSMVSEIPEKKAMAIaDALGKIP-QTVLWRYTGTRPSNLAN---NTILVKWLPQNDLLGHpmTRAFITHAGS 107
Cdd:TIGR01426 225 RPVVLISLGTVFNNQPSFYRTCV-EAFRDLDwHVVLSVGRGVDPADLGElppNVEVRQWVPQLEILKK--ADAFITHGGM 301

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 45827767   108 HGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRL 175
Cdd:TIGR01426 302 NSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEKLREAVLAVLSDPRYAERLRKM 369
PLN02152 PLN02152
indole-3-acetate beta-glucosyltransferase
 1-167 8.74e-14

indole-3-acetate beta-glucosyltransferase


Pssm-ID: 177813 [Multi-domain]  Cd Length: 455  Bit Score: 70.47  E-value: 8.74e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767    1 MPNMVFIGGINCKK--RKDLSQEFEAYINASGEHGIVVFSLGSMVsEIPEKKAMAIADAL--GKIP-------------- 62
Cdd:PLN02152 228 LPAEIFTGSESGKDlsVRDQSSSYTLWLDSKTESSVIYVSFGTMV-ELSKKQIEELARALieGKRPflwvitdklnreak 306

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   63 -----QTVLWRYTGTRpSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRME 137
Cdd:PLN02152 307 iegeeETEIEKIAGFR-HELEEVGMIVSWCSQIEVLRHRAVGCFVTHCGWSSSLESLVLGVPVVAFPMWSDQPANAKLLE 385

                        170       180       190
                 ....*....|....*....|....*....|....
gi 45827767  138 ---TKGAGVTLNVLEMTSE-DLENALKAVINDKS 167
Cdd:PLN02152 386 eiwKTGVRVRENSEGLVERgEIRRCLEAVMEEKS 419
PLN02410 PLN02410
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 25-137 1.96e-13

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 178032 [Multi-domain]  Cd Length: 451  Bit Score: 69.30  E-value: 1.96e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   25 YINASGEHGIVVFSLGSM-VSEIPEkkAMAIADALGKIPQTVLWRytgTRPSNLANNT-----------------ILVKW 86
Cdd:PLN02410 257 WLNKQKKNSVIFVSLGSLaLMEINE--VMETASGLDSSNQQFLWV---IRPGSVRGSEwieslpkefskiisgrgYIVKW 331

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 45827767   87 LPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRME 137
Cdd:PLN02410 332 APQKEVLSHPAVGGFWSHCGWNSTLESIGEGVPMICKPFSSDQKVNARYLE 382
PLN02210 PLN02210
UDP-glucosyl transferase
 25-162 3.36e-10

UDP-glucosyl transferase


Pssm-ID: 215127 [Multi-domain]  Cd Length: 456  Bit Score: 59.66  E-value: 3.36e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   25 YINASGEHGIVVFSLGSMVSEIpEKKAMAIADALGKIPQTVLWRytgTRPSNLANNT------------ILVKWLPQNDL 92
Cdd:PLN02210 262 WLDKQARSSVVYISFGSMLESL-ENQVETIAKALKNRGVPFLWV---IRPKEKAQNVqvlqemvkegqgVVLEWSPQEKI 337

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 45827767   93 LGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNVL----EMTSEDLENALKAV 162
Cdd:PLN02210 338 LSHMAISCFVTHCGWNSTIETVVAGVPVVAYPSWTDQPIDARLLvDVFGIGVRMRNDavdgELKVEEVERCIEAV 412
PLN02555 PLN02555
limonoid glucosyltransferase
 83-174 6.34e-10

limonoid glucosyltransferase


Pssm-ID: 178170 [Multi-domain]  Cd Length: 480  Bit Score: 59.04  E-value: 6.34e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   83 LVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTL------NVLEMTSEDL 155
Cdd:PLN02555 341 IVQWCPQEKVLAHPSVACFVTHCGWNSTMEALSSGVPVVCFPQWGDQVTDAVYLvDVFKTGVRLcrgeaeNKLITREEVA 420

                         90       100
                 ....*....|....*....|.
gi 45827767  156 ENALKAVINDKS--YKENIMR 174
Cdd:PLN02555 421 ECLLEATVGEKAaeLKQNALK 441
PLN02173 PLN02173
UDP-glucosyl transferase family protein
 25-178 9.21e-10

UDP-glucosyl transferase family protein


Pssm-ID: 177830 [Multi-domain]  Cd Length: 449  Bit Score: 58.50  E-value: 9.21e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   25 YINASGEHGIVVFSLGSMvSEIPEKKAMAIADALGKIpqTVLWRYTGTRPSNL---------ANNTILVKWLPQNDLLGH 95
Cdd:PLN02173 257 WLDKRPQGSVVYIAFGSM-AKLSSEQMEEIASAISNF--SYLWVVRASEESKLppgfletvdKDKSLVLKWSPQLQVLSN 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   96 PMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRME-TKGAGVTLNVLEMTS----EDLENALKAVIN---DKS 167
Cdd:PLN02173 334 KAIGCFMTHCGWNSTMEGLSLGVPMVAMPQWTDQPMNAKYIQdVWKVGVRVKAEKESGiakrEEIEFSIKEVMEgekSKE 413

                        170
                 ....*....|.
gi 45827767  168 YKENIMRLSSL 178
Cdd:PLN02173 414 MKENAGKWRDL 424
PLN03015 PLN03015
UDP-glucosyl transferase
 25-153 1.11e-09

UDP-glucosyl transferase


Pssm-ID: 178589 [Multi-domain]  Cd Length: 470  Bit Score: 58.17  E-value: 1.11e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   25 YINASGEHGIVVFSLGSMvSEIPEKKAMAIADALGKIPQTVLW------RYTG-----------TRPSNLANNT-----I 82
Cdd:PLN03015 260 WLDKQGERSVVYVCLGSG-GTLTFEQTVELAWGLELSGQRFVWvlrrpaSYLGasssdddqvsaSLPEGFLDRTrgvglV 338

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 45827767   83 LVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKrMETKGAGVTLNVLEMTSE 153
Cdd:PLN03015 339 VTQWAPQVEILSHRSIGGFLSHCGWSSVLESLTKGVPIVAWPLYAEQWMNAT-LLTEEIGVAVRTSELPSE 408
PLN03004 PLN03004
UDP-glycosyltransferase
 2-177 1.36e-09

UDP-glycosyltransferase


Pssm-ID: 178581  Cd Length: 451  Bit Score: 58.16  E-value: 1.36e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767    2 PNMVFIGGINCKKRKDLSQEFEA-----YINASGEHGIVVFSLGSMvSEIPEKKAMAIADALGKIPQTVLWryTGTRPSN 76
Cdd:PLN03004 235 RNIYPIGPLIVNGRIEDRNDNKAvsclnWLDSQPEKSVVFLCFGSL-GLFSKEQVIEIAVGLEKSGQRFLW--VVRNPPE 311

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   77 LANNTILVK--------------------WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM 136
Cdd:PLN03004 312 LEKTELDLKsllpegflsrtedkgmvvksWAPQVPVLNHKAVGGFVTHCGWNSILEAVCAGVPMVAWPLYAEQRFNRVMI 391

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 45827767  137 -ETKGAGVTLNVLE---MTSEDLENALKAVINDKSYKENIMRLSS 177
Cdd:PLN03004 392 vDEIKIAISMNESEtgfVSSTEVEKRVQEIIGECPVRERTMAMKN 436
PLN00164 PLN00164
glucosyltransferase; Provisional
 85-133 2.31e-09

glucosyltransferase; Provisional


Pssm-ID: 215084 [Multi-domain]  Cd Length: 480  Bit Score: 57.37  E-value: 2.31e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 45827767   85 KWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 133
Cdd:PLN00164 345 TWAPQKEILAHAAVGGFVTHCGWNSVLESLWHGVPMAPWPLYAEQHLNA 393
PLN02534 PLN02534
UDP-glycosyltransferase
 82-147 2.58e-09

UDP-glycosyltransferase


Pssm-ID: 215293 [Multi-domain]  Cd Length: 491  Bit Score: 57.18  E-value: 2.58e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 45827767   82 ILVK-WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNV 147
Cdd:PLN02534 346 LLIKgWAPQVLILSHPAIGGFLTHCGWNSTIEGICSGVPMITWPLFAEQFLNEKLIvEVLRIGVRVGV 413
PLN02992 PLN02992
coniferyl-alcohol glucosyltransferase
 86-133 4.73e-09

coniferyl-alcohol glucosyltransferase


Pssm-ID: 178572 [Multi-domain]  Cd Length: 481  Bit Score: 56.53  E-value: 4.73e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 45827767   86 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 133
Cdd:PLN02992 345 WAPQAEILAHQAVGGFLTHCGWSSTLESVVGGVPMIAWPLFAEQNMNA 392
PLN02562 PLN02562
UDP-glycosyltransferase
 34-175 3.67e-08

UDP-glycosyltransferase


Pssm-ID: 215305  Cd Length: 448  Bit Score: 53.73  E-value: 3.67e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   34 IVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYT-----GTRPS---NLANNTILVKWLPQNDLLGHPMTRAFITHA 105
Cdd:PLN02562 275 VIYISFGSWVSPIGESNVRTLALALEASGRPFIWVLNpvwreGLPPGyveRVSKQGKVVSWAPQLEVLKHQAVGCYLTHC 354

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 45827767  106 GSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNvlEMTSEDLENALKAVINDKSYKENIMRL 175
Cdd:PLN02562 355 GWNSTMEAIQCQKRLLCYPVAGDQFVNCAYIvDVWKIGVRIS--GFGQKEVEEGLRKVMEDSGMGERLMKL 423
PLN02554 PLN02554
UDP-glycosyltransferase family protein
 83-176 9.58e-08

UDP-glycosyltransferase family protein


Pssm-ID: 215304  Cd Length: 481  Bit Score: 52.48  E-value: 9.58e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   83 LVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTL-----------NVLEM 150
Cdd:PLN02554 346 VIGWAPQVAVLAKPAIGGFVTHCGWNSILESLWFGVPMAAWPLYAEQKFNAFEMvEELGLAVEIrkywrgdllagEMETV 425

                         90       100
                 ....*....|....*....|....*..
gi 45827767  151 TSEDLENALKAVI-NDKSYKENIMRLS 176
Cdd:PLN02554 426 TAEEIERGIRCLMeQDSDVRKRVKEMS 452
PLN02167 PLN02167
UDP-glycosyltransferase family protein
 31-136 1.92e-07

UDP-glycosyltransferase family protein


Pssm-ID: 215112 [Multi-domain]  Cd Length: 475  Bit Score: 51.34  E-value: 1.92e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   31 EHGIVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLW--RYTGTR--------PSNLANNT----ILVKWLPQNDLLGHP 96
Cdd:PLN02167 279 ESSVVFLCFGSLGS-LPAPQIKEIAQALELVGCRFLWsiRTNPAEyaspyeplPEGFMDRVmgrgLVCGWAPQVEILAHK 357

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 45827767   97 MTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM 136
Cdd:PLN02167 358 AIGGFVSHCGWNSVLESLWFGVPIATWPMYAEQQLNAFTM 397
PLN02448 PLN02448
UDP-glycosyltransferase family protein
 24-134 3.00e-07

UDP-glycosyltransferase family protein


Pssm-ID: 215247 [Multi-domain]  Cd Length: 459  Bit Score: 50.78  E-value: 3.00e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   24 AYINASGEHGIVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLW---RYTGTRPSNLANNTILVKWLPQNDLLGHPMTRA 100
Cdd:PLN02448 266 QWLDSQPEGSVLYVSLGSFLS-VSSAQMDEIAAGLRDSGVRFLWvarGEASRLKEICGDMGLVVPWCDQLKVLCHSSVGG 344

                         90       100       110
                 ....*....|....*....|....*....|....
gi 45827767  101 FITHAGSHGVYESICNGVPMVMMPLFGDQMDNAK 134
Cdd:PLN02448 345 FWTHCGWNSTLEAVFAGVPMLTFPLFWDQPLNSK 378
PLN02863 PLN02863
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 82-133 9.52e-07

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 215465  Cd Length: 477  Bit Score: 49.48  E-value: 9.52e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 45827767   82 ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNA 133
Cdd:PLN02863 346 VIRGWAPQVAILSHRAVGAFLTHCGWNSVLEGLVAGVPMLAWPMAADQFVNA 397
PLN02207 PLN02207
UDP-glycosyltransferase
 16-136 1.07e-06

UDP-glycosyltransferase


Pssm-ID: 177857 [Multi-domain]  Cd Length: 468  Bit Score: 49.27  E-value: 1.07e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   16 KDLSQ--EFEAYINASGEHGIVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLWRYTGTRPSN-----------LANNTI 82
Cdd:PLN02207 257 QDLARrdELMKWLDDQPEASVVFLCFGSMGR-LRGPLVKEIAHGLELCQYRFLWSLRTEEVTNddllpegfldrVSGRGM 335

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 45827767   83 LVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM 136
Cdd:PLN02207 336 ICGWSPQVEILAHKAVGGFVSHCGWNSIVESLWFGVPIVTWPMYAEQQLNAFLM 389
PLN02208 PLN02208
glycosyltransferase family protein
 86-167 2.83e-06

glycosyltransferase family protein


Pssm-ID: 177858  Cd Length: 442  Bit Score: 48.09  E-value: 2.83e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   86 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMdNAKRMETKGAGVTLNVLE-----MTSEDLENALK 160
Cdd:PLN02208 318 WVQQPLILDHPSIGCFVNHCGPGTIWESLVSDCQMVLIPFLSDQV-LFTRLMTEEFEVSVEVSRektgwFSKESLSNAIK 396


                 ....*..
gi 45827767  161 AVINDKS 167
Cdd:PLN02208 397 SVMDKDS 403
PLN03007 PLN03007
UDP-glucosyltransferase family protein
 34-178 7.48e-06

UDP-glucosyltransferase family protein


Pssm-ID: 178584 [Multi-domain]  Cd Length: 482  Bit Score: 46.78  E-value: 7.48e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   34 IVVFSLGSMVSeIPEKKAMAIADALGKIPQTVLW--RYTGTRPSN------------LANNTILVKWLPQNDLLGHPMTR 99
Cdd:PLN03007 287 VIYLSFGSVAS-FKNEQLFEIAAGLEGSGQNFIWvvRKNENQGEKeewlpegfeertKGKGLIIRGWAPQVLILDHQATG 365

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767  100 AFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRM-ETKGAGVTLNVLEM--------TSEDLENALKAVINDKSYKE 170
Cdd:PLN03007 366 GFVTHCGWNSLLEGVAAGLPMVTWPVGAEQFYNEKLVtQVLRTGVSVGAKKLvkvkgdfiSREKVEKAVREVIVGEEAEE 445


                 ....*...
gi 45827767  171 NIMRLSSL 178
Cdd:PLN03007 446 RRLRAKKL 453
Glyco_tran_28_C pfam04101
Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes ...
 102-182 1.38e-05

Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.


Pssm-ID: 427711 [Multi-domain]  Cd Length: 166  Bit Score: 44.24  E-value: 1.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   102 ITHAGSHGVYESICNGVPMVMMPL----FGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSS 177
Cdd:pfam04101  76 ISRAGAGTIAELLALGKPAILVPNpsaaRGHQDNNAKELVKAGAALVILQKELTPEKLIEALLKLLLNPLRLAEMAKASK 155


                  ....*
gi 45827767   178 LHKDR 182
Cdd:pfam04101 156 ASGFK 160
PLN00414 PLN00414
glycosyltransferase family protein
 33-197 1.61e-05

glycosyltransferase family protein


Pssm-ID: 177807 [Multi-domain]  Cd Length: 446  Bit Score: 45.78  E-value: 1.61e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   33 GIVVFSLGSMVSEIPEKKAMAIADALgkiPQTVLWRYTGtrpsnlaNNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYE 112
Cdd:PLN00414 276 GMELTGLPFLIAVMPPKGSSTVQEAL---PEGFEERVKG-------RGIVWEGWVEQPLILSHPSVGCFVNHCGFGSMWE 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767  113 SICNGVPMVMMPLFGDQMdNAKRMETKGAGVTLNVLE-----MTSEDLENALKAVINDKSYKENIMRLSSLH-KDRPVEP 186
Cdd:PLN00414 346 SLVSDCQIVFIPQLADQV-LITRLLTEELEVSVKVQRedsgwFSKESLRDTVKSVMDKDSEIGNLVKRNHKKlKETLVSP 424

                        170
                 ....*....|.
gi 45827767  187 LDLAVFWVEFV 197
Cdd:PLN00414 425 GLLSGYADKFV 435
GT28_MurG cd03785
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4. ...
 102-176 4.01e-05

undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340818 [Multi-domain]  Cd Length: 350  Bit Score: 44.13  E-value: 4.01e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767 102 ITHAGSHGVYESICNGVPMVMMPLF----GDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVIND----KSYKENIM 173
Cdd:cd03785 257 ISRAGASTIAELTAAGKPAILIPYPyaadDHQEANARALEKAGAAIVIDQEELTPEVLAEAILDLLNDperlKKMAEAAK 336


                ...
gi 45827767 174 RLS 176
Cdd:cd03785 337 KLA 339
PLN02764 PLN02764
glycosyltransferase family protein
 86-174 5.28e-05

glycosyltransferase family protein


Pssm-ID: 178364  Cd Length: 453  Bit Score: 43.90  E-value: 5.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767   86 WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKgAGVTLNVLE-----MTSEDLENALK 160
Cdd:PLN02764 324 WVQQPLILSHPSVGCFVSHCGFGSMWESLLSDCQIVLVPQLGDQVLNTRLLSDE-LKVSVEVAReetgwFSKESLRDAIN 402

                         90
                 ....*....|....
gi 45827767  161 AVINDKSYKENIMR 174
Cdd:PLN02764 403 SVMKRDSEIGNLVK 416
PLN02670 PLN02670
transferase, transferring glycosyl groups
 82-143 5.53e-05

transferase, transferring glycosyl groups


Pssm-ID: 178275 [Multi-domain]  Cd Length: 472  Bit Score: 44.12  E-value: 5.53e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 45827767   82 ILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGV 143
Cdd:PLN02670 342 IHVGWVPQVKILSHESVGGFLTHCGWNSVVEGLGFGRVLILFPVLNEQGLNTRLLHGKKLGL 403
MurG COG0707
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope ...
 102-176 7.22e-05

UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440471 [Multi-domain]  Cd Length: 363  Bit Score: 43.58  E-value: 7.22e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767 102 ITHAGSHGVYESICNGVPMVMMPL-F---GDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVIND----KSYKENIM 173
Cdd:COG0707 263 ISRAGASTVAELAALGKPAILVPLpHaadDHQTKNARALVEAGAAVLIPQSELTPEKLAEALEELLEDperlAKMAEAAR 342


                ...
gi 45827767 174 RLS 176
Cdd:COG0707 343 ALA 345
GT28_Beta-DGS-like cd17507
beta-diglucosyldiacylglycerol synthase and similar proteins; beta-diglucosyldiacylglycerol ...
 90-175 5.60e-04

beta-diglucosyldiacylglycerol synthase and similar proteins; beta-diglucosyldiacylglycerol synthase (processive diacylglycerol beta-glucosyltransferase EC 2.4.1.315) is involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. This family of glycosyltransferases also contains plant major galactolipid synthase (chloroplastic monogalactosyldiacylglycerol synthase 1 EC 2.4.1.46). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340861 [Multi-domain]  Cd Length: 364  Bit Score: 40.76  E-value: 5.60e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45827767  90 NDLLGhpMTRAFITHAGSHGVYESICNGVPMVM-MPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSY 168
Cdd:cd17507 262 NELMA--ASDLVITKPGGLTISEALARGLPVIIyDPIPGQEEENADFLENNGAGIIARDPEELLEIVARLIDPPSLLRMM 339


                ....*..
gi 45827767 169 KENIMRL 175
Cdd:cd17507 340 SEAAKEL 346
murG PRK00726
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
 102-174 6.19e-04

undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional


Pssm-ID: 234825 [Multi-domain]  Cd Length: 357  Bit Score: 40.50  E-value: 6.19e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 45827767  102 ITHAGSHGVYESICNGVPMVMMPL----FGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMR 174
Cdd:PRK00726 257 ICRAGASTVAELAAAGLPAILVPLphaaDDHQTANARALVDAGAALLIPQSDLTPEKLAEKLLELLSDPERLEAMAE 333
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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