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Conserved domains on  [gi|41406094|ref|NP_957714|]
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dnaJ homolog subfamily C member 12 isoform b [Homo sapiens]

Protein Classification

J domain-containing protein( domain architecture ID 10446266)

J domain-containing protein containing a similar domain as DnaJ, a protein that plays crucial roles in protein translation, folding, unfolding, translocation, and degradation, primarily by stimulating the ATPase activity of Hsp70.

CATH:  1.10.287.110
Gene Ontology:  GO:0006457
PubMed:  15170475|9644977
SCOP:  4000605

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 14-76 3.33e-22

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


:

Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 81.75  E-value: 3.33e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41406094    14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYD 76
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
 
Name Accession Description Interval E-value
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 14-76 3.33e-22

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 81.75  E-value: 3.33e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41406094    14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYD 76
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 14-68 5.42e-16

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 66.03  E-value: 5.42e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 41406094  14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTN 68
Cdd:cd06257   1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDDPEAEEKFKEINEAYEVLSD 55
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 14-76 9.20e-15

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 65.11  E-value: 9.20e-15
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41406094  14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYD 76
Cdd:COG0484   1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGDPEAEEKFKEINEAYEVLSDPEKRAAYD 63
PRK14289 PRK14289
molecular chaperone DnaJ;
14-84 1.61e-13

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 64.85  E-value: 1.61e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 41406094   14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYDHWRRSQMS 84
Cdd:PRK14289   6 DYYEVLGVSKTATVDEIKKAYRKKAIQYHPDKNPGDKEAEEKFKEAAEAYDVLSDPDKRSRYDQFGHAGVG 76
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 14-76 4.01e-12

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 60.69  E-value: 4.01e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41406094    14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPeNPKAVETFQKLQKAKEILTNEESRARYD 76
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNK-DKEAEEKFKEINEAYEVLSDPEKRAQYD 62
DnaJ smart00271
DnaJ molecular chaperone homology domain;
13-71 6.12e-12

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 55.70  E-value: 6.12e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 41406094     13 EDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPK-AVETFQKLQKAKEILTNEES 71
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKEeAEEKFKEINEAYEVLSDPEK 60
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
10-78 4.69e-09

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 52.13  E-value: 4.69e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 41406094   10 EDTEDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPEnPKAVETFQKLQKAKEILTNEESRARYDHW 78
Cdd:NF037946   2 EEKRDYYEVLGVDRDADDQEIKKAFRKLAKKYHPDRNKA-PDAAEIFAEINEAYEVLSNPEKRANYDKY 69
 
Name Accession Description Interval E-value
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 14-76 3.33e-22

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 81.75  E-value: 3.33e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41406094    14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYD 76
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 14-68 5.42e-16

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 66.03  E-value: 5.42e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 41406094  14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTN 68
Cdd:cd06257   1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDDPEAEEKFKEINEAYEVLSD 55
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 14-76 9.20e-15

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 65.11  E-value: 9.20e-15
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41406094  14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYD 76
Cdd:COG0484   1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGDPEAEEKFKEINEAYEVLSDPEKRAAYD 63
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
11-89 2.67e-14

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 62.81  E-value: 2.67e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41406094  11 DTEDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENP-KAVETFQKLQKAKEILTNEESRARYDHWRRSQMSMPFQQ 89
Cdd:COG2214   3 DLKDHYAVLGVPPDASLEEIRQAYRRLAKLLHPDRGGELKaLAEELFQRLNEAYEVLSDPERRAEYDRELGQSGKGSASQ 82
PRK14289 PRK14289
molecular chaperone DnaJ;
14-84 1.61e-13

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 64.85  E-value: 1.61e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 41406094   14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYDHWRRSQMS 84
Cdd:PRK14289   6 DYYEVLGVSKTATVDEIKKAYRKKAIQYHPDKNPGDKEAEEKFKEAAEAYDVLSDPDKRSRYDQFGHAGVG 76
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 14-78 4.88e-13

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 63.29  E-value: 4.88e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 41406094   14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYDHW 78
Cdd:PRK14281   4 DYYEVLGVSRSADKDEIKKAYRKLALKYHPDKNPDNKEAEEHFKEVNEAYEVLSNDDKRRRYDQF 68
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 13-92 5.94e-13

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 62.89  E-value: 5.94e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41406094   13 EDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPK-AVETFQKLQKAKEILTNEESRARYDHWRRSQMSMPFQQWE 91
Cdd:PRK14282   4 KDYYEILGVSRNATQEEIKRAYKRLVKEWHPDRHPENRKeAEQKFKEIQEAYEVLSDPQKRAMYDRFGYVGEQPPYQETE 83


                 .
gi 41406094   92 A 92
Cdd:PRK14282  84 S 84
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 14-76 1.47e-12

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 62.07  E-value: 1.47e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41406094   14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYD 76
Cdd:PRK14301   5 DYYEVLGVSRDASEDEIKKAYRKLALQYHPDRNPDNPEAEQKFKEAAEAYEVLRDAEKRARYD 67
SEC63 COG5407
Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular ...
 14-74 3.69e-12

Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444165 [Multi-domain]  Cd Length: 61  Bit Score: 56.55  E-value: 3.69e-12
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 41406094  14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRAR 74
Cdd:COG5407   1 DPYEVLGVAKTASADEIKKAYRKLAKKYHPDRNKGDPKAEERFKEINEAYELLSDAEKRAR 61
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 14-76 4.01e-12

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 60.69  E-value: 4.01e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41406094    14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPeNPKAVETFQKLQKAKEILTNEESRARYD 76
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNK-DKEAEEKFKEINEAYEVLSDPEKRAQYD 62
DnaJ smart00271
DnaJ molecular chaperone homology domain;
13-71 6.12e-12

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 55.70  E-value: 6.12e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 41406094     13 EDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPK-AVETFQKLQKAKEILTNEES 71
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKEeAEEKFKEINEAYEVLSDPEK 60
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 14-76 2.12e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 58.62  E-value: 2.12e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41406094   14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYD 76
Cdd:PRK10767   5 DYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGDKEAEEKFKEIKEAYEVLSDPQKRAAYD 67
PRK14279 PRK14279
molecular chaperone DnaJ;
14-80 2.20e-11

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 58.59  E-value: 2.20e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 41406094   14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYDHWRR 80
Cdd:PRK14279  10 DFYKELGVSSDASAEEIKKAYRKLARELHPDANPGDPAAEERFKAVSEAHDVLSDPAKRKEYDETRR 76
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 12-76 3.11e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 58.32  E-value: 3.11e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 41406094   12 TEDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPEnPKAVETFQKLQKAKEILTNEESRARYD 76
Cdd:PRK14298   4 TRDYYEILGLSKDASVEDIKKAYRKLAMKYHPDKNKE-PDAEEKFKEISEAYAVLSDAEKRAQYD 67
PRK14297 PRK14297
molecular chaperone DnaJ;
13-76 3.14e-11

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 58.26  E-value: 3.14e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 41406094   13 EDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYD 76
Cdd:PRK14297   4 KDYYEVLGLEKGASDDEIKKAFRKLAIKYHPDKNKGNKEAEEKFKEINEAYQVLSDPQKKAQYD 67
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 14-78 5.84e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 57.59  E-value: 5.84e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 41406094   14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPEnPKAVETFQKLQKAKEILTNEESRARYDHW 78
Cdd:PRK14292   3 DYYELLGVSRTASADEIKSAYRKLALKYHPDRNKE-KGAAEKFAQINEAYAVLSDAEKRAHYDRF 66
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 11-78 6.04e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 57.50  E-value: 6.04e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 41406094   11 DTEDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYDHW 78
Cdd:PRK14277   3 AKKDYYEILGVDRNATEEEIKKAYRRLAKKYHPDLNPGDKEAEQKFKEINEAYEILSDPQKRAQYDQF 70
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 13-76 6.65e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 57.25  E-value: 6.65e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 41406094   13 EDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPEN-PKAVETFQKLQKAKEILTNEESRARYD 76
Cdd:PRK14290   3 KDYYKILGVDRNASQEDIKKAFRELAKKWHPDLHPGNkAEAEEKFKEISEAYEVLSDPQKRRQYD 67
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 14-78 1.14e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 56.70  E-value: 1.14e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 41406094   14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYDHW 78
Cdd:PRK14294   5 DYYEILGVTRDASEEEIKKSYRKLAMKYHPDRNPGDKEAEELFKEAAEAYEVLSDPKKRGIYDQY 69
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 14-78 8.01e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 54.08  E-value: 8.01e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 41406094   14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYDHW 78
Cdd:PRK14284   2 DYYTILGVSKTASPEEIKKAYRKLAVKYHPDKNPGDAEAEKRFKEVSEAYEVLSDAQKRESYDRY 66
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 11-83 1.07e-09

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 53.68  E-value: 1.07e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41406094   11 DTEDYYTLLGCDELSSVEQILAEFKVRALECHPDKHpENPKAVETFQKLQKAKEILTNEESRARYDHWRRSQM 83
Cdd:PRK14283   3 EKRDYYEVLGVDRNADKKEIKKAYRKLARKYHPDVS-EEEGAEEKFKEISEAYAVLSDDEKRQRYDQFGHAGM 74
PRK14295 PRK14295
molecular chaperone DnaJ;
13-79 2.30e-09

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 52.93  E-value: 2.30e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 41406094   13 EDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYDHWR 79
Cdd:PRK14295   9 KDYYKVLGVPKDATEAEIKKAYRKLAREYHPDANKGDAKAEERFKEISEAYDVLSDEKKRKEYDEAR 75
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
10-78 4.69e-09

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 52.13  E-value: 4.69e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 41406094   10 EDTEDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPEnPKAVETFQKLQKAKEILTNEESRARYDHW 78
Cdd:NF037946   2 EEKRDYYEVLGVDRDADDQEIKKAFRKLAKKYHPDRNKA-PDAAEIFAEINEAYEVLSNPEKRANYDKY 69
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 13-78 4.71e-09

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 51.92  E-value: 4.71e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 41406094   13 EDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYDHW 78
Cdd:PRK14285   3 RDYYEILGLSKGASKDEIKKAYRKIAIKYHPDKNKGNKEAESIFKEATEAYEVLIDDNKRAQYDRF 68
PRK14293 PRK14293
molecular chaperone DnaJ;
14-76 1.17e-08

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 50.76  E-value: 1.17e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41406094   14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPEnPKAVETFQKLQKAKEILTNEESRARYD 76
Cdd:PRK14293   4 DYYEILGVSRDADKDELKRAYRRLARKYHPDVNKE-PGAEDRFKEINRAYEVLSDPETRARYD 65
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 15-84 2.65e-08

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 49.99  E-value: 2.65e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41406094   15 YYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYDHWRRSQMS 84
Cdd:PRK14286   6 YYDILGVSKSANDEEIKSAYRKLAIKYHPDKNKGNKESEEKFKEATEAYEILRDPKKRQAYDQFGKAGVN 75
PRK14280 PRK14280
molecular chaperone DnaJ;
14-76 2.85e-08

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 49.72  E-value: 2.85e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41406094   14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPEnPKAVETFQKLQKAKEILTNEESRARYD 76
Cdd:PRK14280   5 DYYEVLGVSKSASKDEIKKAYRKLSKKYHPDINKE-EGADEKFKEISEAYEVLSDDQKRAQYD 66
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 13-88 7.97e-08

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 48.40  E-value: 7.97e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 41406094   13 EDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPEnPKAVETFQKLQKAKEILTNEESRARYDHWRRSQMSMPFQ 88
Cdd:PRK14299   4 KDYYAILGVPKNASQDEIKKAFKKLARKYHPDVNKS-PGAEEKFKEINEAYTVLSDPEKRRIYDTYGTTAASAGWQ 78
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 14-76 1.11e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 48.12  E-value: 1.11e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41406094   14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPEnPKAVETFQKLQKAKEILTNEESRARYD 76
Cdd:PRK14278   4 DYYGLLGVSRNASDAEIKRAYRKLARELHPDVNPD-EEAQEKFKEISVAYEVLSDPEKRRIVD 65
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 14-78 1.38e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 47.70  E-value: 1.38e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 41406094   14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPEnPKAVETFQKLQKAKEILTNEESRARYDHW 78
Cdd:PRK14287   5 DYYEVLGVDRNASVDEVKKAYRKLARKYHPDVNKA-PDAEDKFKEVKEAYDTLSDPQKKAHYDQF 68
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 14-91 2.64e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 47.07  E-value: 2.64e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 41406094   14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHPeNPKAVETFQKLQKAKEILTNEESRARYDHWRRSQMSMPFQQWE 91
Cdd:PRK14291   4 DYYEILGVSRNATQEEIKKAYRRLARKYHPDFNK-NPEAEEKFKEINEAYQVLSDPEKRKLYDQFGHAAFSGSGQQQQ 80
PRK10266 PRK10266
curved DNA-binding protein;
13-91 3.90e-07

curved DNA-binding protein;


Pssm-ID: 182347 [Multi-domain]  Cd Length: 306  Bit Score: 46.35  E-value: 3.90e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41406094   13 EDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPEnPKAVETFQKLQKAKEILTNEESRARYDHWRRSQMSMPF-QQWE 91
Cdd:PRK10266   4 KDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKE-PDAEARFKEVAEAWEVLSDEQRRAEYDQLWQHRNDPQFnRQFQ 82
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 13-78 4.81e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 46.23  E-value: 4.81e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 41406094   13 EDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPEnPKAVETFQKLQKAKEILTNEESRARYDHW 78
Cdd:PRK14276   4 TEYYDRLGVSKDASQDEIKKAYRKLSKKYHPDINKE-PGAEEKYKEVQEAYETLSDPQKRAAYDQY 68
termin_org_DnaJ TIGR03835
terminal organelle assembly protein TopJ; This model describes TopJ (MG_200, CbpA), a DnaJ ...
 14-78 8.65e-07

terminal organelle assembly protein TopJ; This model describes TopJ (MG_200, CbpA), a DnaJ homolog and probable assembly protein of the Mycoplasma terminal organelle. The terminal organelle is involved in both cytadherence and gliding motility. [Cellular processes, Chemotaxis and motility]


Pssm-ID: 274808 [Multi-domain]  Cd Length: 871  Bit Score: 45.58  E-value: 8.65e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 41406094    14 DYYTLLGCDELSSVEQILAEFKVRALECHPDKHpENPKAVETFQKLQKAKEILTNEESRARYDHW 78
Cdd:TIGR03835   3 DYYEVLGIDRDADEQEIKKAFRKLAKKYHPDRN-KAPDAASIFAEINEANDVLSNPKKRANYDKY 66
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 13-103 1.18e-06

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 45.32  E-value: 1.18e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41406094   13 EDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPEnPKAVETFQKLQKAKEILTNEESRARYDHWRR------SQMSMP 86
Cdd:PRK14296   4 KDYYEVLGVSKTASEQEIRQAYRKLAKQYHPDLNKS-PDAHDKMVEINEAADVLLDKDKRKQYDQFGHaafdgsSGFSSN 82

                         90
                 ....*....|....*..
gi 41406094   87 FQQWEALNDSVKTVGFS 103
Cdd:PRK14296  83 FGDFEDLFSNMGSSGFS 99
PRK14288 PRK14288
molecular chaperone DnaJ;
15-84 1.77e-05

molecular chaperone DnaJ;


Pssm-ID: 172776 [Multi-domain]  Cd Length: 369  Bit Score: 41.98  E-value: 1.77e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41406094   15 YYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEILTNEESRARYDHWRRSQMS 84
Cdd:PRK14288   5 YYEILEVEKHSNQETIKKSYRKLALKYHPDRNAGDKEAEEKFKLINEAYGVLSDEKKRALYDRYGKKGLN 74
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 8-76 1.90e-05

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 41.73  E-value: 1.90e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 41406094    8 RSEDTEDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENpkavETFQKLQKAKEILTNEESRARYD 76
Cdd:PTZ00037  23 REVDNEKLYEVLNLSKDCTTSEIKKAYRKLAIKHHPDKGGDP----EKFKEISRAYEVLSDPEKRKIYD 87
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 12-78 1.21e-04

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 39.61  E-value: 1.21e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 41406094   12 TEDYYTLLGCDELSSVEQILAEFKVRALECHPDKhPENPKAVETFQKLQKAKEILTNEESRARYDHW 78
Cdd:PRK14300   2 SQDYYQILGVSKTASQADLKKAYLKLAKQYHPDT-TDAKDAEKKFKEINAAYDVLKDEQKRAAYDRF 67
ZUO1 COG5269
Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / ...
 12-76 1.90e-04

Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227594 [Multi-domain]  Cd Length: 379  Bit Score: 38.86  E-value: 1.90e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41406094  12 TEDYYTLLGCDEL---SSVEQILAEFKVRALECHPDKHPE--NPKAVETFQKLQKAKEILTNEESRARYD 76
Cdd:COG5269  42 KVDLYALLGLSKYrtkAIPPQILKAHKKKVYKYHPDKTAAggNKGCDEFFKLIQKAREVLGDRKLRLQYD 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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