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Conserved domains on  [gi|47059163|ref|NP_957696|]
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coatomer subunit gamma-1 isoform 2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SEC21 super family cl34951
Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion];
7-107 1.82e-27

Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion];


The actual alignment was detected with superfamily member COG5240:

Pssm-ID: 227565 [Multi-domain]  Cd Length: 898  Bit Score: 105.47  E-value: 1.82e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47059163   7 KKDEESGGGSNPlqhlEKSAVLQEAR-VFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLR 85
Cdd:COG5240   7 KKFMKTKVFTTL----TERTLLQDMNeSFNKSPVSTRSARKLLSNLFYLLSTGELFPEATATNLFFAILKLFQHKDLYLR 82

                        90       100
                ....*....|....*....|..
gi 47059163  86 RMCYLTIKEMSCIAEDVIIVTS 107
Cdd:COG5240  83 QCVYSAIKELSKLTEDVLMGTS 104
 
Name Accession Description Interval E-value
SEC21 COG5240
Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion];
7-107 1.82e-27

Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion];


Pssm-ID: 227565 [Multi-domain]  Cd Length: 898  Bit Score: 105.47  E-value: 1.82e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47059163   7 KKDEESGGGSNPlqhlEKSAVLQEAR-VFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLR 85
Cdd:COG5240   7 KKFMKTKVFTTL----TERTLLQDMNeSFNKSPVSTRSARKLLSNLFYLLSTGELFPEATATNLFFAILKLFQHKDLYLR 82

                        90       100
                ....*....|....*....|..
gi 47059163  86 RMCYLTIKEMSCIAEDVIIVTS 107
Cdd:COG5240  83 QCVYSAIKELSKLTEDVLMGTS 104
Adaptin_N pfam01602
Adaptin N terminal region; This family consists of the N terminal region of various alpha, ...
 23-107 3.52e-22

Adaptin N terminal region; This family consists of the N terminal region of various alpha, beta and gamma subunits of the AP-1, AP-2 and AP-3 adaptor protein complexes. The adaptor protein (AP) complexes are involved in the formation of clathrin-coated pits and vesicles. The N-terminal region of the various adaptor proteins (APs) is constant by comparison to the C-terminal which is variable within members of the AP-2 family; and it has been proposed that this constant region interacts with another uniform component of the coated vesicles.


Pssm-ID: 396262 [Multi-domain]  Cd Length: 523  Bit Score: 89.99  E-value: 3.52e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47059163    23 EKSAVLQE-ARVFNETPINPRKCAHILTKILYLINQGEHlgtteATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAED 101
Cdd:pfam01602   1 EEKRIQQElARILNSFRDDPRKKKNAVKKLLYLIMLGED-----ISFLFFEVVKLVASKDFTLKRLGYLYLMLLAEESPD 75


                  ....*..
gi 47059163   102 V-IIVTS 107
Cdd:pfam01602  76 LaILVTN 82
 
Name Accession Description Interval E-value
SEC21 COG5240
Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion];
7-107 1.82e-27

Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion];


Pssm-ID: 227565 [Multi-domain]  Cd Length: 898  Bit Score: 105.47  E-value: 1.82e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47059163   7 KKDEESGGGSNPlqhlEKSAVLQEAR-VFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLR 85
Cdd:COG5240   7 KKFMKTKVFTTL----TERTLLQDMNeSFNKSPVSTRSARKLLSNLFYLLSTGELFPEATATNLFFAILKLFQHKDLYLR 82

                        90       100
                ....*....|....*....|..
gi 47059163  86 RMCYLTIKEMSCIAEDVIIVTS 107
Cdd:COG5240  83 QCVYSAIKELSKLTEDVLMGTS 104
Adaptin_N pfam01602
Adaptin N terminal region; This family consists of the N terminal region of various alpha, ...
 23-107 3.52e-22

Adaptin N terminal region; This family consists of the N terminal region of various alpha, beta and gamma subunits of the AP-1, AP-2 and AP-3 adaptor protein complexes. The adaptor protein (AP) complexes are involved in the formation of clathrin-coated pits and vesicles. The N-terminal region of the various adaptor proteins (APs) is constant by comparison to the C-terminal which is variable within members of the AP-2 family; and it has been proposed that this constant region interacts with another uniform component of the coated vesicles.


Pssm-ID: 396262 [Multi-domain]  Cd Length: 523  Bit Score: 89.99  E-value: 3.52e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47059163    23 EKSAVLQE-ARVFNETPINPRKCAHILTKILYLINQGEHlgtteATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAED 101
Cdd:pfam01602   1 EEKRIQQElARILNSFRDDPRKKKNAVKKLLYLIMLGED-----ISFLFFEVVKLVASKDFTLKRLGYLYLMLLAEESPD 75


                  ....*..
gi 47059163   102 V-IIVTS 107
Cdd:pfam01602  76 LaILVTN 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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