|
Name |
Accession |
Description |
Interval |
E-value |
| SMYLE_N |
pfam18615 |
Short myomegalin-like EB1 binding proteins, N-terminal domain; This N-terminal region is found ... |
1-376 |
0e+00 |
|
Short myomegalin-like EB1 binding proteins, N-terminal domain; This N-terminal region is found in SMYLE (for short myomegalin-like EB1 binding protein). It includes the SMYLE homology (SmyH) domain found in the first 100 residues at the N terminus. This conserved SmyH domain is required and sufficient for PKA scaffolding protein AKAP9, and the pericentrosomal protein CDK5RAP2 binding.
Pssm-ID: 465822 Cd Length: 387 Bit Score: 664.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 1 MKEICRICARELCGNQRRWIFHTASKLNLQVLLSHVLGKDVSRDGKAEFACSKCAFMLDRIYRFDTVIARIEALSLERLQ 80
Cdd:pfam18615 1 MKEACRICARELCGNQRRWIFHPAAKLNLQVLLSHALGRELTRDGRGEFACSKCAFMLDRMYRFDTVIARVEALSIERLQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 81 KLLLEKDRLKFCIASMYRKNN-DDSGEENKAGSGTVDISGLPDMRYAALLQEDFAYSGFECWVENEDQINDSHSCHASEG 159
Cdd:pfam18615 81 KLLLEKDRLRQCIAGLYRKNNsEESGPEDKVGDGTVDLSGLPDARYSALLQEDLAYSGYESWAEHEEQALDHHHCHASEG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 160 PGNRPRRCRGCAALRVADSDYEAICKVPRKVARSISYAPSSRWSTSICTEEPALSEVGPPDLASTKVPPDGESMEEGTPG 239
Cdd:pfam18615 161 PGSRPRRCRGCAALRVADSDYEAVCKVPRKVARSISCGPSTRYSASTGNEEPSVSELGPATLGNTKSPCEGESMEEGSPA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 240 SSVESLDASVQ-ASPPQQKDEETERSAKELVKCDYCSDE--QAPQHLCNHKLELALSMIKGLDYKPIQSPRGSKLPIPVK 316
Cdd:pfam18615 241 SSVESLDTTVDvVQPPQQKDEESDKGEKDDRKCDQSSEEktTASSSLSSSGLELALSLLRGCEYRPVQSPRGSRLPVLVK 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 31542051 317 SILPGAKPGHILTNGV-------SSSFLNRPLKPLYRTPVSYPWEISDGQELWDDLCDEYLPIGFQP 376
Cdd:pfam18615 321 SSLSPGGLSYPLLDGSpgaglvcSTSFLSALREPFPQTPLDLQLELSELEELWLDLYVEYPPLRLQQ 387
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
406-1011 |
3.02e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 77.67 E-value: 3.02e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 406 ELQDKIQQTEAtnKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLHQSQ 485
Cdd:COG1196 217 ELKEELKELEA--ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 486 LGQLHSSEGIAPAQQQVALLdlqsalfcsQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRK 565
Cdd:COG1196 295 AELARLEQDIARLEERRREL---------EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 566 ALQHLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQ 645
Cdd:COG1196 366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 646 DRAVALERVIDEKFSA---LEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRArGLEVEQLTATCQNLQ 722
Cdd:COG1196 446 EAAEEEAELEEEEEALlelLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG-VKAALLLAGLRGLAG 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 723 WLKEELETKFGHWQKEQESIIQQLQtslhdrNKEVEDLSAtllcklgpgQSEVAEELCQRLQRKERMLQDLLSDRNKQAV 802
Cdd:COG1196 525 AVAVLIGVEAAYEAALEAALAAALQ------NIVVEDDEV---------AAAAIEYLKAAKAGRATFLPLDKIRARAALA 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 803 EHEMEIQGLLQSMGTREQERQAAAEKMVQAFMERNSELQALRQYLGGKELMTSSQTFisnqpagvtsigphhGEQTDQGS 882
Cdd:COG1196 590 AALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRL---------------REVTLEGE 654
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 883 MQMPSRDDSTSLTAREEASIPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQMELSALQSmmAMQEEELQVQAADL 962
Cdd:COG1196 655 GGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE--EELEEEALEEQLEA 732
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 31542051 963 ESLTRNVQIKEDLIKDLQMQLVDPEDIPAMERLTQEVLLLREKVASVEP 1011
Cdd:COG1196 733 EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGP 781
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
498-1117 |
1.04e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 72.78 E-value: 1.04e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 498 AQQQVALLDLQSALFCSQLEIQ--RLQRLVRQKERQLADGKRCVQLVEAAaQEREHQKEAAW----KHNQELRKALQHLQ 571
Cdd:TIGR02168 209 AEKAERYKELKAELRELELALLvlRLEELREELEELQEELKEAEEELEEL-TAELQELEEKLeelrLEVSELEEEIEELQ 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 572 GELHSKSQQLHVLEaekyNEIRTQGQNIQHLSHSLshkEQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQDRAVAL 651
Cdd:TIGR02168 288 KELYALANEISRLE----QQKQILRERLANLERQL---EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAEL 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 652 ERVIDEKF---SALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTATCQNLQwlKEEL 728
Cdd:TIGR02168 361 EELEAELEeleSRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE--LKEL 438
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 729 ETKFGHWQKEQESIIQQLQTsLHDRNKEVEDLSATLLCKLGPGQSEVAeELCQRLQRKERMLQDL--LSDRNKQAVEHEM 806
Cdd:TIGR02168 439 QAELEELEEELEELQEELER-LEEALEELREELEEAEQALDAAERELA-QLQARLDSLERLQENLegFSEGVKALLKNQS 516
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 807 EIQGLLQSMGTR---EQERQAAAEKMVQAFME----RNSE-----LQALRQYLGGKELM-----------TSSQTFISNQ 863
Cdd:TIGR02168 517 GLSGILGVLSELisvDEGYEAAIEAALGGRLQavvvENLNaakkaIAFLKQNELGRVTFlpldsikgteiQGNDREILKN 596
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 864 PAGVTSIGPHHGEQTDQGSMQMPSR-------DDSTSLTA-----REEASI---------PR--STLGDSDTVAGL---E 917
Cdd:TIGR02168 597 IEGFLGVAKDLVKFDPKLRKALSYLlggvlvvDDLDNALElakklRPGYRIvtldgdlvrPGgvITGGSAKTNSSIlerR 676
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 918 KELSNAKEELELMAKKERESQMELSAL-QSMMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQ-----MQLVDPEDIpA 991
Cdd:TIGR02168 677 REIEELEEKIEELEEKIAELEKALAELrKELEELEEELEQLRKELEELSRQISALRKDLARLEAeveqlEERIAQLSK-E 755
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 992 MERLTQEVLLLREKVASVEPQGQEVSGnKRQQLLLMLEGLVDERSRLNEALQAERQLYSSL-VKFHAQpenSERDGTLQV 1070
Cdd:TIGR02168 756 LTELEAEIEELEERLEEAEEELAEAEA-EIEELEAQIEQLKEELKALREALDELRAELTLLnEEAANL---RERLESLER 831
|
650 660 670 680
....*....|....*....|....*....|....*....|....*..
gi 31542051 1071 ELEGAQVLRTRLEEVLGRSLERLSRLESLAAIGGGELESVQARHKHA 1117
Cdd:TIGR02168 832 RIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
518-1093 |
6.35e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 69.97 E-value: 6.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 518 IQRLQRLVRQKERQLADGKRcvQlVEAAAQEREHQKEAAWKHNQELRKALQHLQGELHSKSQQLHVLEAEK---YNEIRT 594
Cdd:COG1196 188 LERLEDILGELERQLEPLER--Q-AEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELeelEAELAE 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 595 QGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRL 674
Cdd:COG1196 265 LEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEE 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 675 AVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTAtcQNLQWLKEELETkfghwQKEQESIIQQLQTSLHDRN 754
Cdd:COG1196 345 ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE--ELLEALRAAAEL-----AAQLEELEEAEEALLERLE 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 755 KEVEDlsatllcklgpgQSEVAEELcQRLQRKERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAAEKMVQAfm 834
Cdd:COG1196 418 RLEEE------------LEELEEAL-AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL-- 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 835 eRNSELQALRQYLGGKELMTSSQTFISNQPAGVTSIGPHHGEQTDQGSMQMPSRDDSTSLTAREEASIPRSTLGDSDTVA 914
Cdd:COG1196 483 -LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAA 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 915 GLEKELSNAKEELELMAKKERESQMELSALQSMMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQMQLVDPEDIPAMER 994
Cdd:COG1196 562 AIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVT 641
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 995 LTQEVLLLREKVASVEPQGQEVSGNKRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAQPENSERDGTLQVELEG 1074
Cdd:COG1196 642 LAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL 721
|
570
....*....|....*....
gi 31542051 1075 AQVLRTRLEEVLGRSLERL 1093
Cdd:COG1196 722 EEEALEEQLEAEREELLEE 740
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
499-1114 |
1.63e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.81 E-value: 1.63e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 499 QQQVALLDLQSALfcsqLEIQRLQRLVRQKERQLADGKRcvQLVEAAAQEREHQKEAawkhnQELRKALQHLQGELHSKS 578
Cdd:COG1196 219 KEELKELEAELLL----LKLRELEAELEELEAELEELEA--ELEELEAELAELEAEL-----EELRLELEELELELEEAQ 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 579 QQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLDTNEVFLEKL----------RQRIQDRA 648
Cdd:COG1196 288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAeeeleeaeaeLAEAEEAL 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 649 VALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTATCQNLQWLKEEL 728
Cdd:COG1196 368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 729 EtkfgHWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEVAEELcQRLQRKERMLQDLLSDRNKQAVEHEMEI 808
Cdd:COG1196 448 A----EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL-LLLEAEADYEGFLEGVKAALLLAGLRGL 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 809 QGLLQSMGTREQERQAAAE-----KMVQAFMERNSELQALRQYLggKELMTSSQTFISNQPAGVTSIGPHHGEQTdqgsm 883
Cdd:COG1196 523 AGAVAVLIGVEAAYEAALEaalaaALQNIVVEDDEVAAAAIEYL--KAAKAGRATFLPLDKIRARAALAAALARG----- 595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 884 qmpSRDDSTSLTAREEASIPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAMQEEELQVQAADLE 963
Cdd:COG1196 596 ---AIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLA 672
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 964 SLTRNVQIKEDLIkdlqmqlvdpedipamERLTQEVLLLREKVASVEPQGQEVSGNKRQQLLLMLEGLVDERSRLNEALQ 1043
Cdd:COG1196 673 ALLEAEAELEELA----------------ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREE 736
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 31542051 1044 AERQLYSslvkfhAQPENSERDGTLQVELEGAQVLRTRLEEvLGRSLERLSRLEsLAAIggGELESVQARH 1114
Cdd:COG1196 737 LLEELLE------EEELLEEEALEELPEPPDLEELERELER-LEREIEALGPVN-LLAI--EEYEELEERY 797
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
403-1113 |
4.01e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.77 E-value: 4.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 403 HLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLH 482
Cdd:TIGR02168 233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 483 QSQLGQLHSSEGIAPAQQQvalldlqsalfcsqleIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQE 562
Cdd:TIGR02168 313 NLERQLEELEAQLEELESK----------------LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 563 LRKALQHLQGELHSKSQQLHVLEAEkyneirtQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADktLDTNEVFLEKLRQ 642
Cdd:TIGR02168 377 LEEQLETLRSKVAQLELQIASLNNE-------IERLEARLERLEDRRERLQQEIEELLKKLEEAE--LKELQAELEELEE 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 643 RIQDRAVALERVIdekfSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTATCQNLQ 722
Cdd:TIGR02168 448 ELEELQEELERLE----EALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILG 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 723 WLKEELETKFGhWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEVAEElcqrlqrkermlqDLLSDRNKQAV 802
Cdd:TIGR02168 524 VLSELISVDEG-YEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPL-------------DSIKGTEIQGN 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 803 EHEM--EIQGLLQSMGTREqERQAAAEKMVQAFMER-------NSELQALRQYLGGKELMTSSQTFISnqPAGVTSIGPH 873
Cdd:TIGR02168 590 DREIlkNIEGFLGVAKDLV-KFDPKLRKALSYLLGGvlvvddlDNALELAKKLRPGYRIVTLDGDLVR--PGGVITGGSA 666
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 874 HGEQTDQGSMQmpSRDDSTSLTAREEASIprstlgdsdtvAGLEKELSNAKEELELMAKKERESQMELSALQSMMAMQEE 953
Cdd:TIGR02168 667 KTNSSILERRR--EIEELEEKIEELEEKI-----------AELEKALAELRKELEELEEELEQLRKELEELSRQISALRK 733
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 954 ELQVQAADLESLTRNVQIKEDLIKDLQMQLVDPEDipAMERLTQEVLLLREKVASVEPQGQEVSGNkRQQLLLMLEGLVD 1033
Cdd:TIGR02168 734 DLARLEAEVEQLEERIAQLSKELTELEAEIEELEE--RLEEAEEELAEAEAEIEELEAQIEQLKEE-LKALREALDELRA 810
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 1034 ERSRLNEALQAERQLYSSLVKFHAQPE------------NSERDGTLQVELEGAQVLRTRLEEVLGRSLERLSRLESLAA 1101
Cdd:TIGR02168 811 ELTLLNEEAANLRERLESLERRIAATErrledleeqieeLSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA 890
|
730
....*....|..
gi 31542051 1102 IGGGELESVQAR 1113
Cdd:TIGR02168 891 LLRSELEELSEE 902
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
404-1044 |
5.24e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.84 E-value: 5.24e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 404 LAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLHQ 483
Cdd:TIGR02168 290 LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEE 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 484 SQLGQLHSSEGIAPAQQQVALLDLQSALFCSQLEI--QRLQRLVRQKERQLAD-GKRCVQLVEAAAQE------------ 548
Cdd:TIGR02168 370 LESRLEELEEQLETLRSKVAQLELQIASLNNEIERleARLERLEDRRERLQQEiEELLKKLEEAELKElqaeleeleeel 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 549 ---------REHQKEAAWKHNQELRKALQHLQGELHSKSQQLHVLEAEKyNEIRTQGQNIQHLSHSLSHKEQLIQELQEL 619
Cdd:TIGR02168 450 eelqeelerLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ-ENLEGFSEGVKALLKNQSGLSGILGVLSEL 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 620 LQYRDNADKTLDTnevfleKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLE--------------- 684
Cdd:TIGR02168 529 ISVDEGYEAAIEA------ALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQgndreilkniegflg 602
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 685 ---------------------RLRCVLSANEATMQSMES------------LLRARGL-----------------EVEQL 714
Cdd:TIGR02168 603 vakdlvkfdpklrkalsyllgGVLVVDDLDNALELAKKLrpgyrivtldgdLVRPGGVitggsaktnssilerrrEIEEL 682
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 715 TATCQNLQWLKEELETKfghwQKEQESIIQQLQTSLHDRNKEVEDLSAtllcklgpgQSEVAEELCQRLQRKERMLQDLL 794
Cdd:TIGR02168 683 EEKIEELEEKIAELEKA----LAELRKELEELEEELEQLRKELEELSR---------QISALRKDLARLEAEVEQLEERI 749
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 795 SDRNKQAVEHEMEIQGLLQSMGTREQERQAAAEKMVQafmernseLQAlrQYLGGKELMTSSQTFISNQPAGVTSIGPHH 874
Cdd:TIGR02168 750 AQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE--------LEA--QIEQLKEELKALREALDELRAELTLLNEEA 819
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 875 GEQT-DQGSMQMPSRDDSTSLTAREEASIPRstlgdSDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAMQEE 953
Cdd:TIGR02168 820 ANLReRLESLERRIAATERRLEDLEEQIEEL-----SEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRS 894
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 954 ELQVQAADLESLTRNVQIKEDLIKDLQMQLVDPEDipAMERLTQEVLLLREKVASVEPQGQEVSGNKRQQLLLMLEGLVD 1033
Cdd:TIGR02168 895 ELEELSEELRELESKRSELRRELEELREKLAQLEL--RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARR 972
|
730
....*....|.
gi 31542051 1034 ERSRLNEALQA 1044
Cdd:TIGR02168 973 RLKRLENKIKE 983
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
548-832 |
1.74e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.93 E-value: 1.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 548 EREHQKEAAWKHNQELRKALQHLQGELHSKSQQLHVLE-----AEKYNEIRTQGQNIQHLSHsLSHKEQLIQELQELLQY 622
Cdd:TIGR02169 167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRrerekAERYQALLKEKREYEGYEL-LKEKEALERQKEAIERQ 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 623 RDNADKTLDTNEVFLEKLRQRIQDRAVALERvIDEKFSALEEKdkELRQLRLAVRDRDHDLERLRCVLSANEATMQSMES 702
Cdd:TIGR02169 246 LASLEEELEKLTEEISELEKRLEEIEQLLEE-LNKKIKDLGEE--EQLRVKEKIGELEAEIASLERSIAEKERELEDAEE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 703 LLRARGLEVEQLTATcqnlqwlKEELETKFGHWQKEQESI---IQQLQTSLHDRNKEVEDLSATL------LCKLGPGQS 773
Cdd:TIGR02169 323 RLAKLEAEIDKLLAE-------IEELEREIEEERKRRDKLteeYAELKEELEDLRAELEEVDKEFaetrdeLKDYREKLE 395
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 31542051 774 EVAEELcQRLQRKERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAAEKMVQA 832
Cdd:TIGR02169 396 KLKREI-NELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ 453
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
404-1099 |
4.25e-08 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 57.67 E-value: 4.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 404 LAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLHQ 483
Cdd:pfam02463 162 AAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDL 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 484 SQ----LGQLHSSEGIAPAQQQVALLDLQSALFCSQLEIQRLQRLVR-QKERQLADGKRCVQLVEAAAQEREHQKEAAWK 558
Cdd:pfam02463 242 LQellrDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELkLLAKEEEELKSELLKLERRKVDDEEKLKESEK 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 559 HNQELRKALQHLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLDTNEVFLE 638
Cdd:pfam02463 322 EKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 639 KLRQRIQDRAVALERVIDEkfsALEEKDKELRQLRLAVRDRDHDLERLrcvlsANEATMQSMESLLRARGLEVEQLTATc 718
Cdd:pfam02463 402 EEEKEAQLLLELARQLEDL---LKEEKKEELEILEEEEESIELKQGKL-----TEEKEELEKQELKLLKDELELKKSED- 472
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 719 qNLQWLKEELEtkfgHWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGP------------GQSEVAEELCQRLQRK 786
Cdd:pfam02463 473 -LLKETQLVKL----QEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGvggriisahgrlGDLGVAVENYKVAIST 547
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 787 ERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAAEKMVQAFMERNSELQALRQYLGGKELMTSSQTFISNQPAG 866
Cdd:pfam02463 548 AVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEG 627
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 867 VTSIGPHHGEQTDQGSMQMPSRDDSTSLTAREEASiPRSTLGDSDTVAGLEKELSNAKEELELMAKKERE-----SQMEL 941
Cdd:pfam02463 628 ILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKS-EVKASLSELTKELLEIQELQEKAESELAKEEILRrqleiKKKEQ 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 942 SALQSMMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQMQLVDPEDIPAMERLTQEV----LLLREKVASVEPQGQEVS 1017
Cdd:pfam02463 707 REKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEekseLSLKEKELAEEREKTEKL 786
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 1018 GNKRQQLLLMLEGLVDERS-----RLNEALQAERQLYSSLVKFHAQPENSERDGTLQVELEGAQVLRTRLEEVLGRSLER 1092
Cdd:pfam02463 787 KVEEEKEEKLKAQEEELRAleeelKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKE 866
|
....*..
gi 31542051 1093 LSRLESL 1099
Cdd:pfam02463 867 ELLQELL 873
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
406-1098 |
2.55e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.07 E-value: 2.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 406 ELQDKIQQTEATnkilqeklnDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREmlhqsQ 485
Cdd:TIGR02169 215 ALLKEKREYEGY---------ELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNK-----K 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 486 LGQLHSSEGIApaqqqvalldLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRK 565
Cdd:TIGR02169 281 IKDLGEEEQLR----------VKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERK 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 566 ALQHLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQ 645
Cdd:TIGR02169 351 RRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIA 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 646 DravaLERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTATCQNLqwlk 725
Cdd:TIGR02169 431 G----IEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARAS---- 502
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 726 EELETKFGHWQKEQESIIQQLQTSLHDRNKeVEDLSATLLCKLGPGQ--------SEVAEELCQRLQRKE--RM----LQ 791
Cdd:TIGR02169 503 EERVRGGRAVEEVLKASIQGVHGTVAQLGS-VGERYATAIEVAAGNRlnnvvvedDAVAKEAIELLKRRKagRAtflpLN 581
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 792 DLLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAaekMVQAF-----MERnseLQALRQYLGGKELMT---------SSQ 857
Cdd:TIGR02169 582 KMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPA---FKYVFgdtlvVED---IEAARRLMGKYRMVTlegelfeksGAM 655
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 858 TFISNQPAGVTSIGPHHGEQTDQGSMQMPSRDDSTSLTAREEASIPRSTLGDSDTVAGLEKELSNAKEELELMAKKERES 937
Cdd:TIGR02169 656 TGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL 735
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 938 QMELSALQSMMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQMQLVDPEDIPAMER---LTQEVLLLREKVASVEPQGQ 1014
Cdd:TIGR02169 736 KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRipeIQAELSKLEEEVSRIEARLR 815
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 1015 EVSG--NKRQQLLLMLEGLVDERSRLNEALQAERqlysslVKFHAQPENSE-RDGTLQVELEGAQVLRTRLEEVLGRSLE 1091
Cdd:TIGR02169 816 EIEQklNRLTLEKEYLEKEIQELQEQRIDLKEQI------KSIEKEIENLNgKKEELEEELEELEAALRDLESRLGDLKK 889
|
....*..
gi 31542051 1092 RLSRLES 1098
Cdd:TIGR02169 890 ERDELEA 896
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
404-1003 |
6.33e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 53.97 E-value: 6.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 404 LAELQDKIQQTEATNKILQEKLNDLScelksaqESSQKQDTTIQSLKEMLKSRESETEELYqviegqndtMAKLREMlhQ 483
Cdd:pfam15921 262 LQQHQDRIEQLISEHEVEITGLTEKA-------SSARSQANSIQSQLEIIQEQARNQNSMY---------MRQLSDL--E 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 484 SQLGQLHSS--EGIAPAQQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQERE-----HQKEAA 556
Cdd:pfam15921 324 STVSQLRSElrEAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKElslekEQNKRL 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 557 WKHNQELRKALQHLQGELHSKSQQLHVLEA-------EKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKT 629
Cdd:pfam15921 404 WDRDTGNSITIDHLRRELDDRNMEVQRLEAllkamksECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEE 483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 630 LDTNEVFLEKLRQRIQDRAVALErvidEKFSALEEKDKELRQLRLAVRDRDHDLERLRCV---LSANEATMQSMESLLRA 706
Cdd:pfam15921 484 LTAKKMTLESSERTVSDLTASLQ----EKERAIEATNAEITKLRSRVDLKLQELQHLKNEgdhLRNVQTECEALKLQMAE 559
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 707 RGLEVEQLTATCQNLQWLKEELETKFGHWQKEQesiiQQLQTSLHDRNKEVEDLSatLLCKLGPGQSEVAEELCQRLQRK 786
Cdd:pfam15921 560 KDKVIEILRQQIENMTQLVGQHGRTAGAMQVEK----AQLEKEINDRRLELQEFK--ILKDKKDAKIRELEARVSDLELE 633
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 787 ERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAAEK---MVQAFMERNSELQALRQYLggKELMTSSQTFISNQ 863
Cdd:pfam15921 634 KVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDyevLKRNFRNKSEEMETTTNKL--KMQLKSAQSELEQT 711
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 864 PAGVTSIgphhgEQTDQGSMQMpsrddstSLTAREEASIPRSTLGD-SDTVAGLEKELSNAKEELELMAKKERESQMELS 942
Cdd:pfam15921 712 RNTLKSM-----EGSDGHAMKV-------AMGMQKQITAKRGQIDAlQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELS 779
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 31542051 943 ALQSMMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQMQLVDPEDIpaMERLTQEVLLLR 1003
Cdd:pfam15921 780 TVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDI--IQRQEQESVRLK 838
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
453-956 |
1.15e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 52.85 E-value: 1.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 453 LKSRESETEELYQVIEGQND-----TMAKLREMLHQS---QLGQLHSSEGIAPAQQQVALLDLQSALFCSQLEIQRLQRL 524
Cdd:COG4717 14 FRDRTIEFSPGLNVIYGPNEagkstLLAFIRAMLLERlekEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAEL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 525 VRQKERQLADGKRCVQLVEAAAQEREH--QKEAAWKHNQELRKALQHLQGElhsksqqlhvleAEKYNEIRTQGQNIQHL 602
Cdd:COG4717 94 QEELEELEEELEELEAELEELREELEKleKLLQLLPLYQELEALEAELAEL------------PERLEELEERLEELREL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 603 SHSLSHKEQLIQELQELLQ--YRDNADKTLDTNEVFLEKLrQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRdRD 680
Cdd:COG4717 162 EEELEELEAELAELQEELEelLEQLSLATEEELQDLAEEL-EELQQRLAELEEELEEAQEELEELEEELEQLENELE-AA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 681 HDLERLR------------CVLSANEATMQSMESLLRARGLEVEQLTATCQNLQWLKEELETKFGHwQKEQESIIQQLQT 748
Cdd:COG4717 240 ALEERLKearlllliaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAE-ELQALPALEELEE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 749 SLHDRNKEVEDLSATLLCKLGPGQSEVAEELCQRLQRKERMLQDLlsdrnkQAVEHEMEIQGLLQSMGTREQERQAAAEK 828
Cdd:COG4717 319 EELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL------QLEELEQEIAALLAEAGVEDEEELRAALE 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 829 MVQAFMERNSELQALRQYLGGKElmtssqTFISNQPAGVTSIGPHHGEQTDQGSMQMPSRDDSTSLTAREEASIPRSTLG 908
Cdd:COG4717 393 QAEEYQELKEELEELEEQLEELL------GELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLE 466
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 31542051 909 DSDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAMQEEELQ 956
Cdd:COG4717 467 EDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
406-765 |
2.21e-06 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 51.94 E-value: 2.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 406 ELQDKIQQTEATNKILQEKLNDLSCE-------LKSAQESSQKQDTTIQSLKEMLKSRESETEELYQviEGQNDTMAKLR 478
Cdd:TIGR04523 236 KKQQEINEKTTEISNTQTQLNQLKDEqnkikkqLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNN--QKEQDWNKELK 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 479 EMLH---------QSQLGQlhSSEGIAPAQQQVAllDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQER 549
Cdd:TIGR04523 314 SELKnqekkleeiQNQISQ--NNKIISQLNEQIS--QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNL 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 550 EHQKEAAWKHNQELRKALQHLQGELHSKSQQLHVLEAEKYN---EIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNA 626
Cdd:TIGR04523 390 ESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERlkeTIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQ 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 627 DKTL----DTNEVFLEKLRQRIQDRAVALERVIDEKfSALEEKDKELRQ----LRLAVRDRDHDLERLRCVLSANEATMQ 698
Cdd:TIGR04523 470 LKVLsrsiNKIKQNLEQKQKELKSKEKELKKLNEEK-KELEEKVKDLTKkissLKEKIEKLESEKKEKESKISDLEDELN 548
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 699 SMESLLRARGLEvEQLTATCQNLQWLKEE---LETKfghwQKEQESIIQQLQTSLHDRNKEVEDLSATLL 765
Cdd:TIGR04523 549 KDDFELKKENLE-KEIDEKNKEIEELKQTqksLKKK----QEEKQELIDQKEKEKKDLIKEIEEKEKKIS 613
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
404-629 |
2.60e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.92 E-value: 2.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 404 LAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLhQ 483
Cdd:COG4942 29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL-A 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 484 SQLGQLHSSEGIAPaqqqVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQEL 563
Cdd:COG4942 108 ELLRALYRLGRQPP----LALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAEL 183
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 31542051 564 RKALQHLQGELHSKSQQLHVLEAekynEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKT 629
Cdd:COG4942 184 EEERAALEALKAERQKLLARLEK----ELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
472-687 |
2.71e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.84 E-value: 2.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 472 DTMAKLREMLHQ-SQLGQLHssEGIAPAQQQVALLdlqsalfcsqleiQRLQRLVRQKERQLADGKRCVQLVEAAAQERE 550
Cdd:COG4913 222 DTFEAADALVEHfDDLERAH--EALEDAREQIELL-------------EPIRELAERYAAARERLAELEYLRAALRLWFA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 551 HQKEAAWKHNQE-LRKALQHLQGELHSKSQQLHVLEAEkYNEIRTQ-----GQNIQHLSHSLSHKEQLIQEL-QELLQYR 623
Cdd:COG4913 287 QRRLELLEAELEeLRAELARLEAELERLEARLDALREE-LDELEAQirgngGDRLEQLEREIERLERELEEReRRRARLE 365
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 31542051 624 DNADK---TLDTNEVFLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLR 687
Cdd:COG4913 366 ALLAAlglPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLE 432
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
419-963 |
2.81e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 51.66 E-value: 2.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 419 KILQEKLNDlSCELKSAQESSQKQDT-TIQS-LKEMLKSRESETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGIA 496
Cdd:pfam15921 88 KDLQRRLNE-SNELHEKQKFYLRQSViDLQTkLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLE 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 497 PAQQQVAllDLQSALFCSQLEIQRLQRLVRQKERqlADGKRCVQLVEAAAQEREHQKEAAWKHNQELRKALQHLQGELHS 576
Cdd:pfam15921 167 DSNTQIE--QLRKMMLSHEGVLQEIRSILVDFEE--ASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFP 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 577 KSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLiqELQELLQYRDNADKTLDTNEVFLEKLRQRIQDRAVALERVID 656
Cdd:pfam15921 243 VEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEV--EITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLS 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 657 EKFSALEEKDKELRQLRLAVRDRDHDLERlRCVLSANEATMQSME--SLLRARGLEVEQLTATCQNLQWLKEEL----ET 730
Cdd:pfam15921 321 DLESTVSQLRSELREAKRMYEDKIEELEK-QLVLANSELTEARTErdQFSQESGNLDDQLQKLLADLHKREKELslekEQ 399
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 731 KFGHWQKEQ-ESI-IQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEVAEELC------QRLQRKERMLQDLLSDRN--KQ 800
Cdd:pfam15921 400 NKRLWDRDTgNSItIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAaiqgknESLEKVSSLTAQLESTKEmlRK 479
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 801 AVEHEMEIQGLLQSMGTREQERQAAAEKMVQAFMERNSELQALRQYLggkELMTSSQTFISNQPAGVTsigpHHGEQTDQ 880
Cdd:pfam15921 480 VVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRV---DLKLQELQHLKNEGDHLR----NVQTECEA 552
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 881 GSMQMPSRDDSTSLTaREEASIPRSTLGDSDTVAG--------LEKELSNAKEELElmakkeresqmELSALQSMMAMQE 952
Cdd:pfam15921 553 LKLQMAEKDKVIEIL-RQQIENMTQLVGQHGRTAGamqvekaqLEKEINDRRLELQ-----------EFKILKDKKDAKI 620
|
570
....*....|.
gi 31542051 953 EELQVQAADLE 963
Cdd:pfam15921 621 RELEARVSDLE 631
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
637-1116 |
7.02e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 50.42 E-value: 7.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 637 LEKLRQRIQDRAVALERVIDEKFSALEEKDKE------------LRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLL 704
Cdd:PRK02224 164 LEEYRERASDARLGVERVLSDQRGSLDQLKAQieekeekdlherLNGLESELAELDEEIERYEEQREQARETRDEADEVL 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 705 ---RARGLEVEQLTATCQNLQWLKEELEtkfghwqKEQESI---IQQLQTSLHDRNKEVEDLSATllCKLGPGQSEVAEE 778
Cdd:PRK02224 244 eehEERREELETLEAEIEDLRETIAETE-------REREELaeeVRDLRERLEELEEERDDLLAE--AGLDDADAEAVEA 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 779 LCQRLQRKERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTRE------QERQAAAEKMVQ----AFMERNSELQALRqylg 848
Cdd:PRK02224 315 RREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEeraeelREEAAELESELEeareAVEDRREEIEELE---- 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 849 gKELMTSSQTFiSNQPAGVTSIGPHHGEQTDQGSmqmPSRDDSTSLTAR---------------------------EEAS 901
Cdd:PRK02224 391 -EEIEELRERF-GDAPVDLGNAEDFLEELREERD---ELREREAELEATlrtarerveeaealleagkcpecgqpvEGSP 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 902 IPRSTLGDSDTVAGLEKELSNAKEELELMAKK--------ERESQME-----LSALQSMMAMQEEELQVQAADLESLTRN 968
Cdd:PRK02224 466 HVETIEEDRERVEELEAELEDLEEEVEEVEERleraedlvEAEDRIErleerREDLEELIAERRETIEEKRERAEELRER 545
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 969 VQikedlikDLQMQLVDPEDipAMERLTQEVLLLREKVASVEPQGQEV-----SGNKRQQLLLMLEGLVDERSRLNEALQ 1043
Cdd:PRK02224 546 AA-------ELEAEAEEKRE--AAAEAEEEAEEAREEVAELNSKLAELkerieSLERIRTLLAAIADAEDEIERLREKRE 616
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 1044 A------ERQLYSSlvkfhaqpENSERDGTLQVE-----LEGAQVLRTRLEEVLGRSLERLSRLES-----LAAIGG--- 1104
Cdd:PRK02224 617 AlaelndERRERLA--------EKRERKRELEAEfdearIEEAREDKERAEEYLEQVEEKLDELREerddlQAEIGAven 688
|
570
....*....|....
gi 31542051 1105 --GELESVQARHKH 1116
Cdd:PRK02224 689 elEELEELRERREA 702
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
401-671 |
1.17e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 49.67 E-value: 1.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 401 ESHLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREm 480
Cdd:TIGR02168 781 EAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA- 859
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 481 lhqsqlgqlhssegiapaqqqvALLDLQSALFCSQLEIQRLQRLVRQKERQLAdgkrcvqLVEAAAQEREHQKEAAWKHN 560
Cdd:TIGR02168 860 ----------------------EIEELEELIEELESELEALLNERASLEEALA-------LLRSELEELSEELRELESKR 910
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 561 QELRKALQHLQGELHSKSQQLHVLEaekyneirtqgQNIQHLSHSLSHKEQLiqELQELLQYRDNADKTLDTNEVFLEKL 640
Cdd:TIGR02168 911 SELRRELEELREKLAQLELRLEGLE-----------VRIDNLQERLSEEYSL--TLEEAEALENKIEDDEEEARRRLKRL 977
|
250 260 270
....*....|....*....|....*....|.
gi 31542051 641 RQRIQDRAVALERVIDEkFSALEEKDKELRQ 671
Cdd:TIGR02168 978 ENKIKELGPVNLAAIEE-YEELKERYDFLTA 1007
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
562-839 |
1.80e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 49.28 E-value: 1.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 562 ELRKALQHLQgelhSKSQQlhvleAEKYNEIRTQGQNIQhLSHSLSHKEQLIQELQELlqyrdnadktldtnevflEKLR 641
Cdd:TIGR02168 197 ELERQLKSLE----RQAEK-----AERYKELKAELRELE-LALLVLRLEELREELEEL------------------QEEL 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 642 QRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTATCQNL 721
Cdd:TIGR02168 249 KEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEEL 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 722 QWLKEELETKFGHWQKEQESIiQQLQTSLHDRNKEVEDLSATLLcklgpGQSEVAEELCQRLQRKERMLQDLLSDRNKQA 801
Cdd:TIGR02168 329 ESKLDELAEELAELEEKLEEL-KEELESLEAELEELEAELEELE-----SRLEELEEQLETLRSKVAQLELQIASLNNEI 402
|
250 260 270
....*....|....*....|....*....|....*...
gi 31542051 802 VEHEMEIQGLLQSMGTREQERQAAAEKMVQAFMERNSE 839
Cdd:TIGR02168 403 ERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA 440
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
427-848 |
1.90e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 48.81 E-value: 1.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 427 DLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELyQVIEGQNDTMAKLREMLhQSQLGQLHSSEGI---APAQQQVA 503
Cdd:TIGR00618 369 EISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDIL-QREQATIDTRTSAFRDL-QGQLAHAKKQQELqqrYAELCAAA 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 504 LLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRKALQH-------------- 569
Cdd:TIGR00618 447 ITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHpnparqdidnpgpl 526
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 570 --------------------LQGELHSKSQQLHVLEAEKYNEIRTQ---GQNIQHLSHSLSHKEQLIQELQELLQYRDNA 626
Cdd:TIGR00618 527 trrmqrgeqtyaqletseedVYHQLTSERKQRASLKEQMQEIQQSFsilTQCDNRSKEDIPNLQNITVRLQDLTEKLSEA 606
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 627 -DKTLDTNEVFLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRC----VLSANEATMQSME 701
Cdd:TIGR00618 607 eDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVlpkeLLASRQLALQKMQ 686
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 702 SLLRARGLEVEQLTATCQNLQWLKEELET---KFGHWQKEQESIIQQLQTSLHDRN---KEVEDLSATLLCKLGPGQSEV 775
Cdd:TIGR00618 687 SEKEQLTYWKEMLAQCQTLLRELETHIEEydrEFNEIENASSSLGSDLAAREDALNqslKELMHQARTVLKARTEAHFNN 766
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 31542051 776 AEELCQRLQR--KERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTR----EQERQAAAEKMVQAFMERNSELQALRQYLG 848
Cdd:TIGR00618 767 NEEVTAALQTgaELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEipsdEDILNLQCETLVQEEEQFLSRLEEKSATLG 845
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
507-793 |
3.44e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 48.14 E-value: 3.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 507 LQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRKALQHLQGELHSKSQQLHVLEA 586
Cdd:TIGR02169 707 LSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA 786
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 587 --------EKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQDRAVALERVIDEK 658
Cdd:TIGR02169 787 rlshsripEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEEL 866
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 659 FSALEEKDKELRQLrlavRDRDHDLERLRcvlsaneatmQSMESLLRARGLEVEQLTATCQNLQWLKEELETKFGhwqke 738
Cdd:TIGR02169 867 EEELEELEAALRDL----ESRLGDLKKER----------DELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE----- 927
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 31542051 739 qesiiqqlqtSLHDRNKEVEDLSATLLCKlgPGQSEVAEELCQRLQRKERMLQDL 793
Cdd:TIGR02169 928 ----------ALEEELSEIEDPKGEDEEI--PEEELSLEDVQAELQRVEEEIRAL 970
|
|
| zf-AD |
pfam07776 |
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ... |
4-78 |
4.05e-05 |
|
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.
Pssm-ID: 462262 Cd Length: 75 Bit Score: 42.83 E-value: 4.05e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 31542051 4 ICRICARELcgNQRRWIFHTASK-LNLQVLLSHVLGKDVSR-DGKAEFACSKCAFMLDRIYRFDTVIARIEALSLER 78
Cdd:pfam07776 1 VCRLCLDES--DELIPIFDPSDSeKTLAEILEDCTGIELDPnDLLPKQICERCLSKLQEFYSFRERCLESQELLQEL 75
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
406-845 |
6.35e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 47.42 E-value: 6.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 406 ELQDKIQQTEATNKILQEKLNDlscelksaqessqkQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKlrEMLHQSQ 485
Cdd:pfam15921 146 QLQNTVHELEAAKCLKEDMLED--------------SNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGK--KIYEHDS 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 486 LGQLHSSEGIAPAQQQVALLDlqsalfcsqLEIQRLQRLVRQKERQL----ADGKRCVQLVEAAAQEREHQKEAawKHNQ 561
Cdd:pfam15921 210 MSTMHFRSLGSAISKILRELD---------TEISYLKGRIFPVEDQLealkSESQNKIELLLQQHQDRIEQLIS--EHEV 278
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 562 E---LRKALQHLQGELHSKSQQLHVLEAEKYNEirtQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLD-----TN 633
Cdd:pfam15921 279 EitgLTEKASSARSQANSIQSQLEIIQEQARNQ---NSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlAN 355
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 634 EVFLEKLRQRIQ--DRAVALERVIDEKFSALEEKDKEL-----RQLRLAVRDRDHD--LERLRCVLSANEATMQSMESLL 704
Cdd:pfam15921 356 SELTEARTERDQfsQESGNLDDQLQKLLADLHKREKELslekeQNKRLWDRDTGNSitIDHLRRELDDRNMEVQRLEALL 435
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 705 RARGLEVE-QLTATCQNLQWLKEELEtkfghwqkEQESIIQQLQTSLHDRNKEVEDLSATllcKLGPGQSE-VAEELCQR 782
Cdd:pfam15921 436 KAMKSECQgQMERQMAAIQGKNESLE--------KVSSLTAQLESTKEMLRKVVEELTAK---KMTLESSErTVSDLTAS 504
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 31542051 783 LQRKERMLQDLLSDRNKQAVEHEMEIQGL--LQSMGTREQERQAAAEKMVQAFMERNSELQALRQ 845
Cdd:pfam15921 505 LQEKERAIEATNAEITKLRSRVDLKLQELqhLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQ 569
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
409-1056 |
7.55e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 47.14 E-value: 7.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 409 DKIQQTEATNKILQEKLNDLSCELKSAQ----ESSQKQDTTIQSLKEMLKSRESE----TEELYQVIEGQNDTMAKLREM 480
Cdd:pfam12128 244 TKLQQEFNTLESAELRLSHLHFGYKSDEtliaSRQEERQETSAELNQLLRTLDDQwkekRDELNGELSAADAAVAKDRSE 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 481 LH--QSQLGQLHSSEGIAPAQQQVALLDLQSALFCSQLEIQRL---QRLVRQK--ERQLADGKRCVQLVEAAAQEREHQK 553
Cdd:pfam12128 324 LEalEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALtgkHQDVTAKynRRRSKIKEQNNRDIAGIKDKLAKIR 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 554 EAAWKHNQELRKALQHLQGEL-HSKSQQLHVLEAEKY-------------------NEIRTQGQNIQHLSHSLSHK---- 609
Cdd:pfam12128 404 EARDRQLAVAEDDLQALESELrEQLEAGKLEFNEEEYrlksrlgelklrlnqatatPELLLQLENFDERIERAREEqeaa 483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 610 ----EQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQdravALERVIDEKFSALeekdkeLRQLRLAVRDRDHDLER 685
Cdd:pfam12128 484 naevERLQSELRQARKRRDQASEALRQASRRLEERQSALD----ELELQLFPQAGTL------LHFLRKEAPDWEQSIGK 553
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 686 L-------RCVL--SANEATMQSMESL----LRARGLEVEQLTATCQNLQWLKEELETKFGhwqkEQESIIQQLQTSLHD 752
Cdd:pfam12128 554 VispellhRTDLdpEVWDGSVGGELNLygvkLDLKRIDVPEWAASEEELRERLDKAEEALQ----SAREKQAAAEEQLVQ 629
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 753 RNKEVEDLSATLlcKLGPGQSEVAEELCQRL----QRKERMLQDLLSDRNKQAVEhemEIQGLLQSMGTREQERQAAAEK 828
Cdd:pfam12128 630 ANGELEKASREE--TFARTALKNARLDLRRLfdekQSEKDKKNKALAERKDSANE---RLNSLEAQLKQLDKKHQAWLEE 704
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 829 MVQAFMERNSELQALRQYLGGKelmTSSQtfISNQPAGVTSIGPHHGEQTDQGSMQMpsrddSTSLTAREEasiprstlg 908
Cdd:pfam12128 705 QKEQKREARTEKQAYWQVVEGA---LDAQ--LALLKAAIAARRSGAKAELKALETWY-----KRDLASLGV--------- 765
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 909 DSDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAMQEEELQVQAADLES--------LTRNVQIKEDLIKDLQ 980
Cdd:pfam12128 766 DPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERaiselqqqLARLIADTKLRRAKLE 845
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 981 MQLVDPEDipAMERLTQEVLLLR---EKVASV-EPQGQEVSGNKRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFH 1056
Cdd:pfam12128 846 MERKASEK--QQVRLSENLRGLRcemSKLATLkEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHFKNVIADH 923
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
419-851 |
7.62e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.68 E-value: 7.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 419 KILQEKLNDLsceLKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREmlhqsqlgqlhssegiapA 498
Cdd:COG4717 49 ERLEKEADEL---FKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEE------------------L 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 499 QQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAwkhnQELRKALQHLQGELhskS 578
Cdd:COG4717 108 EAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEEL----EELEAELAELQEEL---E 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 579 QQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLdTNEVFLEKLRQRIQDR--------AVA 650
Cdd:COG4717 181 ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL-ENELEAAALEERLKEArlllliaaALL 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 651 LERVIDEKFSALEEKDKELRQLRLAVrdRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTATCQNLqWLKEELET 730
Cdd:COG4717 260 ALLGLGGSLLSLILTIAGVLFLVLGL--LALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAAL-GLPPDLSP 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 731 KFGHWQKEQESIIQQLQTSLHDRNKEV-----EDLSATLLCKLGPG----------QSEVAEELCQRLQRKERMLQDLLS 795
Cdd:COG4717 337 EELLELLDRIEELQELLREAEELEEELqleelEQEIAALLAEAGVEdeeelraaleQAEEYQELKEELEELEEQLEELLG 416
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 31542051 796 DRNKQAVEHEMEIqglLQSMGTREQERQAAAEKMVQAFMERNSELQALRQYLGGKE 851
Cdd:COG4717 417 ELEELLEALDEEE---LEEELEELEEELEELEEELEELREELAELEAELEQLEEDG 469
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
400-588 |
1.14e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.98 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 400 SESHLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAK-LR 478
Cdd:COG3883 14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGErAR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 479 EMLHQ----SQLGQLHSSEGIAPAQQQVALLD-LQSAlfcSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQK 553
Cdd:COG3883 94 ALYRSggsvSYLDVLLGSESFSDFLDRLSALSkIADA---DADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170
|
170 180 190
....*....|....*....|....*....|....*
gi 31542051 554 EAAWKHNQELRKALQHLQGELHSKSQQLHVLEAEK 588
Cdd:COG3883 171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAEL 205
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
401-1029 |
1.78e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 45.73 E-value: 1.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 401 ESHLAELQDKIQQTEATNKILQEKLNdlscelksAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDtmaKLREM 480
Cdd:TIGR00618 228 LKHLREALQQTQQSHAYLTQKREAQE--------EQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARK---AAPLA 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 481 LHQSQLGQLHSSEGIAPAQQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLveaaaqEREHQKEAAWKHN 560
Cdd:TIGR00618 297 AHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHI------RDAHEVATSIREI 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 561 QELRKALQH----LQGELHSKSQQLHVLEAEKYNEIRTQGQ-NIQHLSHSLSHKEQLIQELQELLQYRDNADKTL-DTNE 634
Cdd:TIGR00618 371 SCQQHTLTQhihtLQQQKTTLTQKLQSLCKELDILQREQATiDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAaITCT 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 635 VFLEKLRQRIQDRAVALERVIDEKFSALE---EKDKELRQLRLAVRDRDHDLERLRC--------------VLSANEATM 697
Cdd:TIGR00618 451 AQCEKLEKIHLQESAQSLKEREQQLQTKEqihLQETRKKAVVLARLLELQEEPCPLCgscihpnparqdidNPGPLTRRM 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 698 QSMESLLRARGLEVEQLTATCQNLQWLKEELETKFGHWQKEQESIIQQLQTSLHDRNKEVEDLSatLLCKLGPGQSEVAE 777
Cdd:TIGR00618 531 QRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITV--RLQDLTEKLSEAED 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 778 ELCQRLQRKERMLQDLLSDRNKQAVEHEME---------IQGLLQSMGTREQERQAAAEKMVQA--FMERNSELQAL--- 843
Cdd:TIGR00618 609 MLACEQHALLRKLQPEQDLQDVRLHLQQCSqelalkltaLHALQLTLTQERVREHALSIRVLPKelLASRQLALQKMqse 688
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 844 -RQYLGGKELMTSSQTFISNQPAGVTSIGPHHGEQtdqgsmQMPSRDDSTSLTAREEA--SIPRSTLGDSDTVAGLEKEL 920
Cdd:TIGR00618 689 kEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEI------ENASSSLGSDLAAREDAlnQSLKELMHQARTVLKARTEA 762
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 921 SNAKEELELMAKKERESQMELSALQSMMAMQEEELQVQAADLESltrnvQIKEDLIKDLQMQLVdpEDIPAMERLTQEVL 1000
Cdd:TIGR00618 763 HFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEA-----EIGQEIPSDEDILNL--QCETLVQEEEQFLS 835
|
650 660 670
....*....|....*....|....*....|..
gi 31542051 1001 LLREKVAS---VEPQGQEVSGNKRQQLLLMLE 1029
Cdd:TIGR00618 836 RLEEKSATlgeITHQLLKYEECSKQLAQLTQE 867
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
609-803 |
1.89e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.14 E-value: 1.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 609 KEQLIQELQELLQYRDNADKTLDTNE---VFLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLER 685
Cdd:COG4942 22 AAEAEAELEQLQQEIAELEKELAALKkeeKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 686 LRCVLSANEATMQSM-------------------------ESLLRARGLEVEQLTATCQNLQWLKEELETKfghwQKEQE 740
Cdd:COG4942 102 QKEELAELLRALYRLgrqpplalllspedfldavrrlqylKYLAPARREQAEELRADLAELAALRAELEAE----RAELE 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 31542051 741 SIIQQLQTSLHDRNKEVEDlSATLLCKLGPGQSEVAEELcQRLQRKERMLQDLLSDRNKQAVE 803
Cdd:COG4942 178 ALLAELEEERAALEALKAE-RQKLLARLEKELAELAAEL-AELQQEAEELEALIARLEAEAAA 238
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
612-1084 |
2.25e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.14 E-value: 2.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 612 LIQELQ-ELLQYRDNADKTLDTNEVFLEKLRQRIQDRAVALERVIdEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVL 690
Cdd:COG4717 47 LLERLEkEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYA-ELQEELEELEEELEELEAELEELREELEKLEKLL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 691 SANE--ATMQSMESLLRARGLEVEQLTATCQNLQWLKEELETKFGHWQKEQESIIQQLQTSLHDRNKEVEDLSATLlckl 768
Cdd:COG4717 126 QLLPlyQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEEL---- 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 769 gpgqsevaeelcQRLQRKERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAAEKMVQAFMERNSELQALRQYLG 848
Cdd:COG4717 202 ------------EELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLL 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 849 GKELMTSSQTFISnqpAGVTSIGPHHGEQTDQGSMQmpSRDDSTSLTAREEASiprstlgdsdtvaglEKELSNAKEELE 928
Cdd:COG4717 270 SLILTIAGVLFLV---LGLLALLFLLLAREKASLGK--EAEELQALPALEELE---------------EEELEELLAALG 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 929 LMAKKERESQMELsalqsmmAMQEEELQVQAADLESLTRNVQIK--EDLIKDL--QMQLVDPEDIPAMERLTQEVLLLRE 1004
Cdd:COG4717 330 LPPDLSPEELLEL-------LDRIEELQELLREAEELEEELQLEelEQEIAALlaEAGVEDEEELRAALEQAEEYQELKE 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 1005 KVASVEPQGQEVSGNKRQQL-LLMLEGLVDERSRLNEALQAER----QLYSSLVKFHAQPENSERDGTLQVELEGAQVLR 1079
Cdd:COG4717 403 ELEELEEQLEELLGELEELLeALDEEELEEELEELEEELEELEeeleELREELAELEAELEQLEEDGELAELLQELEELK 482
|
....*
gi 31542051 1080 TRLEE 1084
Cdd:COG4717 483 AELRE 487
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
522-845 |
2.41e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 45.11 E-value: 2.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 522 QRLVRQKERQLADGKRCVQLVEA-----AAQERE-----HQKEAAWKHNQEL-RKALQHLQGELHSKSQQLHVLEAEKYN 590
Cdd:pfam17380 299 ERLRQEKEEKAREVERRRKLEEAekarqAEMDRQaaiyaEQERMAMERERELeRIRQEERKRELERIRQEEIAMEISRMR 378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 591 EI-RTQGQNIQHlshslshKEQLIQELQELLQYRdnadktldtnevFLEKLRQR-IQDRAVALERVIDEKFSAL------ 662
Cdd:pfam17380 379 ELeRLQMERQQK-------NERVRQELEAARKVK------------ILEEERQRkIQQQKVEMEQIRAEQEEARqrevrr 439
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 663 --EEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEqltatcQNLQWLKEELEtkfghwQKEQE 740
Cdd:pfam17380 440 leEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEE------QRRKILEKELE------ERKQA 507
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 741 SIIQQLQTSLHDrnKEVEDLsatllcklgpgQSEVAEELCQRLQRKERmlqdllsdRNKQAVEHEMEIQgllqsmgtrEQ 820
Cdd:pfam17380 508 MIEEERKRKLLE--KEMEER-----------QKAIYEEERRREAEEER--------RKQQEMEERRRIQ---------EQ 557
|
330 340
....*....|....*....|....*
gi 31542051 821 ERQAAAEKMVQAFMERNSELqaLRQ 845
Cdd:pfam17380 558 MRKATEERSRLEAMEREREM--MRQ 580
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
429-1102 |
2.50e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 45.20 E-value: 2.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 429 SCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMlhqSQLGQLHSSEGIAPAQQQVALLDLQ 508
Cdd:pfam10174 38 SPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQDELRAQRDL---NQLLQQDFTTSPVDGEDKFSTPELT 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 509 SALFcsqleiqrlQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRKALQHLQGE-LHSKSQQLHVLEAE 587
Cdd:pfam10174 115 EENF---------RRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDESIKKLLEMLQSKgLPKKSGEEDWERTR 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 588 KYNEIRTQgqnIQHLSHSLSHKEQLIQELQELLQYRdNADKTLDTNEVFLEKLRQRIQDRAVALERVIDE--------KF 659
Cdd:pfam10174 186 RIAEAEMQ---LGHLEVLLDQKEKENIHLREELHRR-NQLQPDPAKTKALQTVIEMKDTKISSLERNIRDledevqmlKT 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 660 SAL---EEKDKELRQLRLAVRDRD---HDLERLRCVLSANEATMQSMESLLRA---------RGLEV--EQLTATCQNLQ 722
Cdd:pfam10174 262 NGLlhtEDREEEIKQMEVYKSHSKfmkNKIDQLKQELSKKESELLALQTKLETltnqnsdckQHIEVlkESLTAKEQRAA 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 723 WLK----------EELETKFGHWQKEqesiIQQLQTSLHDRNKEVEDLSATLlcklgpgqsEVAEELCQRLQRKERMLQD 792
Cdd:pfam10174 342 ILQtevdalrlrlEEKESFLNKKTKQ----LQDLTEEKSTLAGEIRDLKDML---------DVKERKINVLQKKIENLQE 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 793 LLSDRNKQAVEHEMEIQGLLQSMGTRE------QERQAAAEKMVQAFME--------RNSELQALRQYLGG-KELMTSSQ 857
Cdd:pfam10174 409 QLRDKDKQLAGLKERVKSLQTDSSNTDtalttlEEALSEKERIIERLKEqreredreRLEELESLKKENKDlKEKVSALQ 488
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 858 TFISNQPAGVTSIGPHHGEQTDQG----------------SMQMPSRDDSTSLTAREEASIPRSTLGDSDTVAGLEKELS 921
Cdd:pfam10174 489 PELTEKESSLIDLKEHASSLASSGlkkdsklksleiaveqKKEECSKLENQLKKAHNAEEAVRTNPEINDRIRLLEQEVA 568
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 922 NAKEElelMAKKERESQMELSALQSmMAMQEEELQVQAADLESLTRNvQIKEDLIKDLQMQLVDPEDIPAMERLTQEVll 1001
Cdd:pfam10174 569 RYKEE---SGKAQAEVERLLGILRE-VENEKNDKDKKIAELESLTLR-QMKEQNKKVANIKHGQQEMKKKGAQLLEEA-- 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 1002 LREKVASVEPQGQevsgnkrqqllLMLEGLVDERSRLNEALQAERQLYSSlvkfhAQPENSERDGTLqVELEGAQvlRTR 1081
Cdd:pfam10174 642 RRREDNLADNSQQ-----------LQLEELMGALEKTRQELDATKARLSS-----TQQSLAEKDGHL-TNLRAER--RKQ 702
|
730 740
....*....|....*....|.
gi 31542051 1082 LEEVLGRSLERLsrlesLAAI 1102
Cdd:pfam10174 703 LEEILEMKQEAL-----LAAI 718
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
610-844 |
4.19e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 44.12 E-value: 4.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 610 EQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQDRAVALERVIDEkfsaLEEKDKELRQLRLAVRDRDHDLERLRCV 689
Cdd:pfam07888 37 EECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAE----LKEELRQSREKHEELEEKYKELSASSEE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 690 LSANEATMQSMESLLRARGLEVEQLTATCQNLQWLKE-ELE------TKFGHWQKEQESIIQQLQTSLHDRNKEVEDLSA 762
Cdd:pfam07888 113 LSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLEREtELErmkeraKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSK 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 763 tllcKLGPGQSEVAEELCQRLQRKERMLQdlLSDRNKQAVEHEMEIQGLLQSMGTReQERQAAAEKMVQAFMERNSELQA 842
Cdd:pfam07888 193 ----EFQELRNSLAQRDTQVLQLQDTITT--LTQKLTTAHRKEAENEALLEELRSL-QERLNASERKVEGLGEELSSMAA 265
|
..
gi 31542051 843 LR 844
Cdd:pfam07888 266 QR 267
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
498-710 |
5.12e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 5.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 498 AQQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLVEAAAQEREHQKEAAWKHNQELRKALQHLQGELHSK 577
Cdd:COG4942 30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 578 SQQLHVLEAEKYNEIRTQGQNIQHLSHSLS-------HKEQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQDRAVA 650
Cdd:COG4942 110 LRALYRLGRQPPLALLLSPEDFLDAVRRLQylkylapARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAA 189
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 651 LERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLE 710
Cdd:COG4942 190 LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFA 249
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
403-709 |
8.49e-04 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 43.59 E-value: 8.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 403 HLAELQDKIQQTEATNKILQEKLND--------------LSCELKSAQESSQKQDTTIQSLKEMLK----SRESETEELY 464
Cdd:pfam07111 339 QVAELQEQVTSQSQEQAILQRALQDkaaevevermsakgLQMELSRAQEARRRQQQQTASAEEQLKfvvnAMSSTQIWLE 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 465 QVIEGQNDTMAKLREMLHQSQLG--QLHSSEGIAPAQQQVALLDLQSALFCS---------QLEIQRLQRLVRQKERQLA 533
Cdd:pfam07111 419 TTMTRVEQAVARIPSLSNRLSYAvrKVHTIKGLMARKVALAQLRQESCPPPPpappvdadlSLELEQLREERNRLDAELQ 498
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 534 DGKRCVQLVEAAAQER-EHQKEAAWKHNQELRKALQHLQGELHSKSQQLhvleaekynEIRTQGQN-----IQHLSHSLS 607
Cdd:pfam07111 499 LSAHLIQQEVGRAREQgEAERQQLSEVAQQLEQELQRAQESLASVGQQL---------EVARQGQQesteeAASLRQELT 569
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 608 HKEQLI-QELQE-LLQYRDNADKTLDTNEVFLEKLRqRIQDRAVALERVIDEKFSALEEKDKELRqlRLAVRDRDHDLER 685
Cdd:pfam07111 570 QQQEIYgQALQEkVAEVETRLREQLSDTKRRLNEAR-REQAKAVVSLRQIQHRATQEKERNQELR--RLQDEARKEEGQR 646
|
330 340
....*....|....*....|....
gi 31542051 686 LRCVLSANEATMQSMESLLRARGL 709
Cdd:pfam07111 647 LARRVQELERDKNLMLATLQQEGL 670
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
408-1025 |
1.03e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.50 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 408 QDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDTtiqSLKEMLKSRESETEELYQVIEGQNDTMAKLREMlhQSQLG 487
Cdd:TIGR00606 198 QGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLE---SSREIVKSYENELDPLKNRLKEIEHNLSKIMKL--DNEIK 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 488 QLHSSEGIAPAQQQVALLDLQSALFCSQLEIQRL----QRLVRQKERQLADGKRcvQLVEAAAQEREHQKEAAWKHNQEL 563
Cdd:TIGR00606 273 ALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLyhnhQRTVREKERELVDCQR--ELEKLNKERRLLNQEKTELLVEQG 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 564 RKALQHLQGELHSKSQQLHVLEaekyNEIRTQGQNIQHLSHSlshkEQLIQELQELLQYRDNAD--------KTLDTNEV 635
Cdd:TIGR00606 351 RLQLQADRHQEHIRARDSLIQS----LATRLELDGFERGPFS----ERQIKNFHTLVIERQEDEaktaaqlcADLQSKER 422
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 636 FLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRD---HDLERLRCVLSANEATMQSME--SLLRARGLE 710
Cdd:TIGR00606 423 LKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEgssDRILELDQELRKAERELSKAEknSLTETLKKE 502
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 711 VEQLTATCQNLQWLKEELETKFGHWQKEQESIIQQL-----QTSLHDRNKEVEDLSATLLCKLGP--GQSEVAEELCQRL 783
Cdd:TIGR00606 503 VKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEmltkdKMDKDEQIRKIKSRHSDELTSLLGyfPNKKQLEDWLHSK 582
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 784 QRKERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAAEKMVQA--FMERNSELQALRqylggKELMTSSQTFIs 861
Cdd:TIGR00606 583 SKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVcgSQDEESDLERLK-----EEIEKSSKQRA- 656
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 862 nQPAGVTSIGPHHGEQT---DQGSMQMPSRDDSTSLTAREEAS-IPRSTLGDSDTVAGLEKELSNAKEELELMAKKERES 937
Cdd:TIGR00606 657 -MLAGATAVYSQFITQLtdeNQSCCPVCQRVFQTEAELQEFISdLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGR 735
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 938 QMELSALQSMMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQMQLVDPE----DIPAMERLTQEVLLLREKVASVEPQG 1013
Cdd:TIGR00606 736 QSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKvcltDVTIMERFQMELKDVERKIAQQAAKL 815
|
650
....*....|..
gi 31542051 1014 QEVSGNKRQQLL 1025
Cdd:TIGR00606 816 QGSDLDRTVQQV 827
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
401-836 |
1.15e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.83 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 401 ESHLAELQDKIQQTEATNKILQEKLNDLSCELKSAQESSQKQDT--TIQSLKEMLKSRESETEELYQVIEGQNDTMAKLR 478
Cdd:COG4717 87 EEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLyqELEALEAELAELPERLEELEERLEELRELEEELE 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 479 EMlhqsqlgqlhsSEGIAPAQQQVALLdlqsALFCSQLEIQRLQRLVRQKERqladgkrcvqlVEAAAQEREHQKEAAWK 558
Cdd:COG4717 167 EL-----------EAELAELQEELEEL----LEQLSLATEEELQDLAEELEE-----------LQQRLAELEEELEEAQE 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 559 HNQELRKALQHLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQ----------ELLQYRDNADK 628
Cdd:COG4717 221 ELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLflvlgllallFLLLAREKASL 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 629 TLDTNEVFLEKLRQRIQDRAV-----ALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRcvLSANEATMQSM--- 700
Cdd:COG4717 301 GKEAEELQALPALEELEEEELeellaALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ--LEELEQEIAALlae 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 701 -----ESLLRARGLEVEQLTATCQNLQWLKEELETKFGHWQKEQESII-QQLQTSLHDRNKEVEDLSATLlcklgpgqse 774
Cdd:COG4717 379 agvedEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDeEELEEELEELEEELEELEEEL---------- 448
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 31542051 775 vaEELCQRLQRKERMLQDLLSDRNKQAVEHemEIQGLLQSMgtREQERQAAAEKMVQAFMER 836
Cdd:COG4717 449 --EELREELAELEAELEQLEEDGELAELLQ--ELEELKAEL--RELAEEWAALKLALELLEE 504
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
422-687 |
1.64e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 1.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 422 QEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSREsETEELYQVIEGQNDTMAKLREmlHQSQLGQLhssegiapaQQQ 501
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQ-ERREALQRLAEYSWDEIDVAS--AEREIAEL---------EAE 676
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 502 VALLDLqsalfcSQLEIQRLQRLVRQKERQLADGKRcvQLVEAAAQEREHQKEaaWKHNQELRKALQHLQGELHSKSQQL 581
Cdd:COG4913 677 LERLDA------SSDDLAALEEQLEELEAELEELEE--ELDELKGEIGRLEKE--LEQAEEELDELQDRLEAAEDLARLE 746
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 582 HVLEAEKYNEIRTQGQNIQHLSHSLSHKeqliqelqellqyRDNADKTLDTNEVFLEKLRQRIQDRAVALERVIDEKFSA 661
Cdd:COG4913 747 LRALLEERFAAALGDAVERELRENLEER-------------IDALRARLNRAEEELERAMRAFNREWPAETADLDADLES 813
|
250 260
....*....|....*....|....*.
gi 31542051 662 LEEKDKELRQLrlavrdRDHDLERLR 687
Cdd:COG4913 814 LPEYLALLDRL------EEDGLPEYE 833
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
463-647 |
2.58e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 41.49 E-value: 2.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 463 LYQVIEGQNDTMAKLREMLhqSQLGQLHSSEGIAPAQQQVALLDLQSALFCSQLEIQRLQRLVRQKERQLADGKRCVQLV 542
Cdd:PRK09039 44 LSREISGKDSALDRLNSQI--AELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGEL 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 543 EAAAQEREHQKEAAWKH----NQE---LRKALQHLQGelhsksqqlhVLEAEKyNEIRTQGQNIQHLSHSLShkEQLIQE 615
Cdd:PRK09039 122 AQELDSEKQVSARALAQvellNQQiaaLRRQLAALEA----------ALDASE-KRDRESQAKIADLGRRLN--VALAQR 188
|
170 180 190
....*....|....*....|....*....|..
gi 31542051 616 LQELLQYRDNadktldtnevFLEKLRQRIQDR 647
Cdd:PRK09039 189 VQELNRYRSE----------FFGRLREILGDR 210
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
496-677 |
2.89e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.68 E-value: 2.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 496 APAQQQVALLDLQSALfcsqLEIQRLQRLVRQKERQLADGKrcvQLVEAAAQEREHQKEAAwkhnQELRKALQHLQGELH 575
Cdd:COG1579 1 AMPEDLRALLDLQELD----SELDRLEHRLKELPAELAELE---DELAALEARLEAAKTEL----EDLEKEIKRLELEIE 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 576 SKSQQLHVLEaEKYNEIRTQGQnIQHLSHSLSHKEQLIQEL----QELLQYRDNADKTLDTNEVFLEKLRQRIQdravAL 651
Cdd:COG1579 70 EVEARIKKYE-EQLGNVRNNKE-YEALQKEIESLKRRISDLedeiLELMERIEELEEELAELEAELAELEAELE----EK 143
|
170 180
....*....|....*....|....*.
gi 31542051 652 ERVIDEKFSALEEKDKELRQLRLAVR 677
Cdd:COG1579 144 KAELDEELAELEAELEELEAEREELA 169
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
595-1044 |
2.92e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 41.88 E-value: 2.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 595 QGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKTLDTN---EVFLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQ 671
Cdd:TIGR00618 151 QGEFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKkslHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKH 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 672 LRLAVRDRDHDLERLRCVLSANEATmQSMESLLRARGLEVEQLTATCQNLQWLKEELETKfGHWQK---EQESIIQ--QL 746
Cdd:TIGR00618 231 LREALQQTQQSHAYLTQKREAQEEQ-LKKQQLLKQLRARIEELRAQEAVLEETQERINRA-RKAAPlaaHIKAVTQieQQ 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 747 QTSLHDRNKEVEDLSATLLCKLGPGQSEVAEelcqrLQRKERMLQDLLSDRNKQAVEHEmeiqgllQSMGTREQERQAAA 826
Cdd:TIGR00618 309 AQRIHTELQSKMRSRAKLLMKRAAHVKQQSS-----IEEQRRLLQTLHSQEIHIRDAHE-------VATSIREISCQQHT 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 827 EKmvqafmERNSELQALRQYLGGKELMTSSQTFISNQPAgvtsigphhGEQTDQGSMQMPSRDDSTSLTAREEASIPRST 906
Cdd:TIGR00618 377 LT------QHIHTLQQQKTTLTQKLQSLCKELDILQREQ---------ATIDTRTSAFRDLQGQLAHAKKQQELQQRYAE 441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 907 LGDSdTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQMQLVD- 985
Cdd:TIGR00618 442 LCAA-AITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDi 520
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 31542051 986 ---PEDIPAMERLTQEVLLLREKVASVEPQGQEVSgNKRQQLLLMLEGLVDERSRLNEALQA 1044
Cdd:TIGR00618 521 dnpGPLTRRMQRGEQTYAQLETSEEDVYHQLTSER-KQRASLKEQMQEIQQSFSILTQCDNR 581
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
542-1023 |
3.14e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 41.63 E-value: 3.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 542 VEAAAQEREHQKEAAWKHNQELRKALQHLQGELHSKSQQLHVlEAEKYNEIRTQGQNIQHLSHSLshKEQLIQELQELLQ 621
Cdd:pfam05483 97 IEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEE-EIQENKDLIKENNATRHLCNLL--KETCARSAEKTKK 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 622 YRDNADKT----LDTNE------VFLEKLRQRIQDRAVALERVIDEKFSALEEKDKELRQlrlAVRDRDHDLERLRCVLS 691
Cdd:pfam05483 174 YEYEREETrqvyMDLNNniekmiLAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKK---EINDKEKQVSLLLIQIT 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 692 ANEATMQSMESLLRARGLEVEQLTATCQNLQWLKEELETKFGHWQKEQESIIQQLQTSLHDRNKEVEDL--SATLLCKLG 769
Cdd:pfam05483 251 EKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLqiATKTICQLT 330
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 770 PGQSEVAEELCQ----------RLQRKERMLQDLLSDRNKQAVEHEMEIQGLLQSMgtreQERQAAAEKMVQAFMERNSE 839
Cdd:pfam05483 331 EEKEAQMEELNKakaahsfvvtEFEATTCSLEELLRTEQQRLEKNEDQLKIITMEL----QKKSSELEEMTKFKNNKEVE 406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 840 LQALRQYLGGKE-LMTSSQTF--ISNQPAGVtsigphhgEQTDQGSMQMPSRD------DSTSLTAREEASIprstlgds 910
Cdd:pfam05483 407 LEELKKILAEDEkLLDEKKQFekIAEELKGK--------EQELIFLLQAREKEihdleiQLTAIKTSEEHYL-------- 470
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 911 dtvagleKELSNAKEELElmakKERESQMELSALQSMMAMQEEELQVQAADLESLTRNVQikEDLIKDLQMQlvdpedip 990
Cdd:pfam05483 471 -------KEVEDLKTELE----KEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQ--EDIINCKKQE-------- 529
|
490 500 510
....*....|....*....|....*....|...
gi 31542051 991 amERLTQEVLLLREKVASVEPQGQEVSGNKRQQ 1023
Cdd:pfam05483 530 --ERMLKQIENLEEKEMNLRDELESVREEFIQK 560
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
561-963 |
3.19e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.68 E-value: 3.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 561 QELRKALQHLQGELHSKSQQLHVLEAEkyneIRTQGQNIQHLSHSLSHKEQLIQeLQELLQYRDNADKTLDTNEVFLEKL 640
Cdd:COG4717 77 EEELKEAEEKEEEYAELQEELEELEEE----LEELEAELEELREELEKLEKLLQ-LLPLYQELEALEAELAELPERLEEL 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 641 RQRIQDRA---VALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTAT 717
Cdd:COG4717 152 EERLEELReleEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 718 CQNLQWLKEELET-KFGHWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPgqSEVAEELCQRLQRKERMLQDLLSD 796
Cdd:COG4717 232 LENELEAAALEERlKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGL--LALLFLLLAREKASLGKEAEELQA 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 797 RNKQAVEHEMEIQGLLQSMG---TREQERQAAAEKMVQAFMERNSELQALRQYLGGKELMTSSQTFIsnQPAGVTSIG-- 871
Cdd:COG4717 310 LPALEELEEEELEELLAALGlppDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALL--AEAGVEDEEel 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 872 PHHGEQTDQgsmQMPSRDDSTSLTAR-EEASIPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAM 950
Cdd:COG4717 388 RAALEQAEE---YQELKEELEELEEQlEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQ 464
|
410
....*....|...
gi 31542051 951 QEEELQVQAADLE 963
Cdd:COG4717 465 LEEDGELAELLQE 477
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
590-847 |
3.24e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 41.82 E-value: 3.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 590 NEIRTQGQNIQHLSHSLSHKEQLIQELQELLQYRDNADKtldtNEVFLEKLRQRIQDrAVALERVIDEKFSALEEKDKE- 668
Cdd:PRK11281 39 ADVQAQLDALNKQKLLEAEDKLVQQDLEQTLALLDKIDR----QKEETEQLKQQLAQ-APAKLRQAQAELEALKDDNDEe 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 669 ---------LRQLRLAVRDRDHDL---------------------ERLRCVLSANEATMQSMESLLRARGLEVEQLTATC 718
Cdd:PRK11281 114 tretlstlsLRQLESRLAQTLDQLqnaqndlaeynsqlvslqtqpERAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQ 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 719 QNLqwlkeeletkfghWQKEQESIiqQLQTSLhdRNKEVEdlSATLLCKLGPGQSEVAEELCQRLQRKERMLQDLLSDRN 798
Cdd:PRK11281 194 RVL-------------LQAEQALL--NAQNDL--QRKSLE--GNTQLQDLLQKQRDYLTARIQRLEHQLQLLQEAINSKR 254
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 31542051 799 KQAVEHEMEiqgllqsmgtrEQERQAAAEK-----MVQAFMERNSELQalrQYL 847
Cdd:PRK11281 255 LTLSEKTVQ-----------EAQSQDEAARiqanpLVAQELEINLQLS---QRL 294
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
547-1014 |
3.89e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 41.26 E-value: 3.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 547 QEREHQKEAAWKHNQELRKALQ-------HLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHKEQLIQELQEL 619
Cdd:pfam05557 61 EKREAEAEEALREQAELNRLKKkylealnKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQER 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 620 LQ-YRDNAD-------------KTLDTNEVFLEKLRQRIQDRA--VALERVIDEKFSALEEKDKELRQLRlavrdrdHDL 683
Cdd:pfam05557 141 LDlLKAKASeaeqlrqnlekqqSSLAEAEQRIKELEFEIQSQEqdSEIVKNSKSELARIPELEKELERLR-------EHN 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 684 ERLRCVLSANEATMQSMESlLRARGLEVEQLTATCQNLQWLKEELETKFGHWQKEQESIIQQLQTSLHDRNKEVEDLS-- 761
Cdd:pfam05557 214 KHLNENIENKLLLKEEVED-LKRKLEREEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQLQQre 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 762 ATLLCKLGPGQSEVAEELCQR--LQRKERMLQDLLSDRNKQAVEHEMEIQGLLQSMGTREQER---QAAAEKMVQAFMER 836
Cdd:pfam05557 293 IVLKEENSSLTSSARQLEKARreLEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERdgyRAILESYDKELTMS 372
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 837 NSELQALRQYLGGKELMTSSQTFISNQPAGV-----TSIGPHHGEQTDQGSMQMPSRDDST--SLTAREEASIPRSTLgd 909
Cdd:pfam05557 373 NYSPQLLERIEEAEDMTQKMQAHNEEMEAQLsvaeeELGGYKQQAQTLERELQALRQQESLadPSYSKEEVDSLRRKL-- 450
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 910 sDTVAGLEKELSNAKEELEL-MAKKERESQMELS---ALQSMMAMQEEELQVQAADLESLTRNVQIKEDLIKDLQMQLVD 985
Cdd:pfam05557 451 -ETLELERQRLREQKNELEMeLERRCLQGDYDPKktkVLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQ 529
|
490 500 510
....*....|....*....|....*....|.
gi 31542051 986 PEDIP--AMERLTQEVLLLREKVASVEPQGQ 1014
Cdd:pfam05557 530 VLRLPetTSTMNFKEVLDLRKELESAELKNQ 560
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
571-993 |
4.15e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.21 E-value: 4.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 571 QGELHSKSQQLHVLEaEKYNeIRTQGQNIQHLSHSLSHKEQLIQELQELLQY---RDNADKTLDTNEVFLEKLRQRIQDR 647
Cdd:TIGR02169 119 LSEIHDFLAAAGIYP-EGYN-VVLQGDVTDFISMSPVERRKIIDEIAGVAEFdrkKEKALEELEEVEENIERLDLIIDEK 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 648 AVALERVIDEKFSALEEKD--KELRQLRL-----AVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTATCQN 720
Cdd:TIGR02169 197 RQQLERLRREREKAERYQAllKEKREYEGyellkEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEE 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 721 L-QWLKEELETKFGHWQKEQESI---IQQLQTSLHDRNKEVEDLSATL---LCKLGPGQSEVA--EELCQRLQRKERMLQ 791
Cdd:TIGR02169 277 LnKKIKDLGEEEQLRVKEKIGELeaeIASLERSIAEKERELEDAEERLaklEAEIDKLLAEIEelEREIEEERKRRDKLT 356
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 792 DLLSDRNKQAVEHEMEIQGLLQSMGTREQERQAAAEKMVQAFMERNSELQALRQYLGGKELMTSSQTFISNQPAGVtsig 871
Cdd:TIGR02169 357 EEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGI---- 432
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 872 phHGEQTDQgsmqmpsrdDSTSLTAREEASIPRSTLGD-SDTVAGLEKELSNAKEELELMAKKERESQMELSALQSMMAM 950
Cdd:TIGR02169 433 --EAKINEL---------EEEKEDKALEIKKQEWKLEQlAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARA 501
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 31542051 951 QEEELQVQAADLESLTRNVQIKEDLIKDLQMqlVDPEDIPAME 993
Cdd:TIGR02169 502 SEERVRGGRAVEEVLKASIQGVHGTVAQLGS--VGERYATAIE 542
|
|
| Prominin |
pfam05478 |
Prominin; The prominins are an emerging family of proteins that among the multispan membrane ... |
562-752 |
4.33e-03 |
|
Prominin; The prominins are an emerging family of proteins that among the multispan membrane proteins display a novel topology. Mouse prominin and human prominin (mouse)-like 1 (PROML1) are predicted to contain five membrane spanning domains, with an N-terminal domain exposed to the extracellular space followed by four, alternating small cytoplasmic and large extracellular, loops and a cytoplasmic C-terminal domain. The exact function of prominin is unknown although in humans defects in PROM1, the gene coding for prominin, cause retinal degeneration.
Pssm-ID: 461660 [Multi-domain] Cd Length: 799 Bit Score: 41.07 E-value: 4.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 562 ELRKALQHLQGELHSKSQQLHVLEAEKYNEIRTqgqniqHLSHSLSH-KEQLIQELQEllQYRDNADKTLDTnevfLEKL 640
Cdd:pfam05478 177 TMRRGLRDLRTFLSDVPQHIDHVLVQNYSELQD------HVSDDLDDaGKHIGLDIHD--TLESNVYPALAE----LERI 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 641 RQRIQDRAVALErvidekfsALEEKDKELR----QLRLAVRDRDHDLERL----RCVLSANEATMQSMESLLRARGLEVE 712
Cdd:pfam05478 245 LQNMPEAKDLLE--------QVNALLKDLRfygtQLRDGLRGVKRDLNYAlsnpLCTTQECDKFLSSLSIEFLDTSACLD 316
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 31542051 713 QLTATCQNLQWLKEELETKFghwqkeqESIIQQLQTSLHD 752
Cdd:pfam05478 317 QLPNVDEFLENVKGVIETNL-------SSIVQEGLDRFNN 349
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
903-1115 |
4.68e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.05 E-value: 4.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 903 PRSTLGDSDTVAGLEKELSNAKEELELmAKKERESQMELSALQSMMAMQEEELQVQAADLESLT-----RNVQIKEDLIK 977
Cdd:COG4913 220 EPDTFEAADALVEHFDDLERAHEALED-AREQIELLEPIRELAERYAAARERLAELEYLRAALRlwfaqRRLELLEAELE 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 978 DLQMQLVDPEDipAMERLTQEVLLLREKVASVEPQGQEVSGNKRQQLLLMLEGLVDERSRLNEALQAERQLYSSLvkfHA 1057
Cdd:COG4913 299 ELRAELARLEA--ELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAAL---GL 373
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 31542051 1058 QPENSERDGTLQVE-----LEGAQVLRTRLEEVLGRSLERLSRLESLAAIGGGELESVQARHK 1115
Cdd:COG4913 374 PLPASAEEFAALRAeaaalLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKS 436
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
401-703 |
6.35e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 40.79 E-value: 6.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 401 ESHLAELQDKIQQ-----TEATNKI--LQEKLNDLSCELKSAQESSQKQDTTIQSLKEMLKSRESETEELYQVIEG---- 469
Cdd:PRK02224 320 EDRDEELRDRLEEcrvaaQAHNEEAesLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEElrer 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 470 ------QNDTMAKLREMLhQSQLGQLHSSEGIAPAqqqvalldlqsalfcsqlEIQRLQRLVRQKERQLADGK--RCVQL 541
Cdd:PRK02224 400 fgdapvDLGNAEDFLEEL-REERDELREREAELEA------------------TLRTARERVEEAEALLEAGKcpECGQP 460
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 542 VE-----AAAQEREHQKEaawkhnqELRKALQHLQGELHSKSQQLHVLEAEKYNEirtqgqniqhlshslshkeqliQEL 616
Cdd:PRK02224 461 VEgsphvETIEEDRERVE-------ELEAELEDLEEEVEEVEERLERAEDLVEAE----------------------DRI 511
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 617 QELLQYRDNADKTLDTNEVFLEKLRQRIQ---DRAVALERVIDEKFSALEEKD----------KELRQLRLAVRDRDHDL 683
Cdd:PRK02224 512 ERLEERREDLEELIAERRETIEEKRERAEelrERAAELEAEAEEKREAAAEAEeeaeeareevAELNSKLAELKERIESL 591
|
330 340
....*....|....*....|
gi 31542051 684 ERLRCVLSANEATMQSMESL 703
Cdd:PRK02224 592 ERIRTLLAAIADAEDEIERL 611
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
609-730 |
8.79e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.15 E-value: 8.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 609 KEQLIQELQELLQYRDNADKTLDTNEVFLEKLRQRIQDRavalERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRC 688
Cdd:PRK12704 56 KEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQK----EENLDRKLELLEKREEELEKKEKELEQKQQELEKKEE 131
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 31542051 689 VLSanEATMQSMESLLRARGLEVEQltATCQNLQWLKEELET 730
Cdd:PRK12704 132 ELE--ELIEEQLQELERISGLTAEE--AKEILLEKVEEEARH 169
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
561-845 |
8.81e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 40.42 E-value: 8.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 561 QELRKALQHLQGELHSKSQQLHVLEAEK--YNEIRTQGQNIQHLSHSLSHKE-QLIQELQELLQYRDNADKTLDTNEVFL 637
Cdd:TIGR00606 635 QDEESDLERLKEEIEKSSKQRAMLAGATavYSQFITQLTDENQSCCPVCQRVfQTEAELQEFISDLQSKLRLAPDKLKST 714
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 638 EKLRQRIQDRAVALERVIDEKFSALEEKDKELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTAT 717
Cdd:TIGR00606 715 ESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIM 794
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 718 cQNLQWLKEELETKFGHWQKEQESIiqQLQTSLHDRNKEVEDlsatllcklgpgqsevAEELCQRLQRKERMLQDLLSDR 797
Cdd:TIGR00606 795 -ERFQMELKDVERKIAQQAAKLQGS--DLDRTVQQVNQEKQE----------------KQHELDTVVSKIELNRKLIQDQ 855
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 31542051 798 NKQAVEHEMEIQGLLQ---SMGTREQERQAAAEKMVQAFMERNSELQALRQ 845
Cdd:TIGR00606 856 QEQIQHLKSKTNELKSeklQIGTNLQRRQQFEEQLVELSTEVQSLIREIKD 906
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
388-680 |
9.35e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 40.00 E-value: 9.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 388 DLHETPTTQPPVSESHLAELQDKIQ-QTEATNKILQeklndLSCELKSAQESSQKQDTTIQS-LKEMLKSRESETEELYQ 465
Cdd:COG3206 104 NLDEDPLGEEASREAAIERLRKNLTvEPVKGSNVIE-----ISYTSPDPELAAAVANALAEAyLEQNLELRREEARKALE 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 466 VIEGQndtMAKLREMLHQSQ--LGQLHSSEGIAPAQQQVALL-----DLQSALFCSQLEIQRLQRLVRQKERQLADGKRC 538
Cdd:COG3206 179 FLEEQ---LPELRKELEEAEaaLEEFRQKNGLVDLSEEAKLLlqqlsELESQLAEARAELAEAEARLAALRAQLGSGPDA 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31542051 539 VQLVEAAAQerehqkeaawkhNQELRKALQHLQGELHSKSQQLhvleAEKYNEIRTQGQNIQHLshslshKEQLIQELQE 618
Cdd:COG3206 256 LPELLQSPV------------IQQLRAQLAELEAELAELSARY----TPNHPDVIALRAQIAAL------RAQLQQEAQR 313
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 31542051 619 LLQYRDNADKTLDTNEVFLEKLRQRIQDRAvalervidekfSALEEKDKELRQLRlavRDRD 680
Cdd:COG3206 314 ILASLEAELEALQAREASLQAQLAQLEARL-----------AELPELEAELRRLE---REVE 361
|
|
| |
