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Conserved domains on  [gi|126722757|ref|NP_796272|]
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phosphatidylserine decarboxylase proenzyme, mitochondrial isoform 1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PS_Dcarbxylase super family cl03656
Phosphatidylserine decarboxylase; This is a family of phosphatidylserine decarboxylases, EC:4. ...
 78-404 1.20e-88

Phosphatidylserine decarboxylase; This is a family of phosphatidylserine decarboxylases, EC:4.1.1.65. These enzymes catalyze the reaction: Phosphatidyl-L-serine <=> phosphatidylethanolamine + CO2. Phosphatidylserine decarboxylase plays a central role in the biosynthesis of aminophospholipids by converting phosphatidylserine to phosphatidylethanolamine.


The actual alignment was detected with superfamily member PLN02938:

Pssm-ID: 470849  Cd Length: 428  Bit Score: 274.78  E-value: 1.20e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757  78 RQYE-KYRERKLEKlGLEipPKLASHWEVSLYKSVPTRLLSRACGRLNQVELPYWLRRPVYSLYIWTFGVNMTEAAVEdL 156
Cdd:PLN02938  63 RLYEdKKVEEAREK-GIE--PEFSPDTKASFLRLLPLRSISRLWGSLTSVELPVWMRPYVYKAWARAFHSNLEEAALP-L 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 157 HHYRNLSEFFRRKLKPQARPV-CGLHCVTSPSDGKILTFGQVKNS--EVEQVKGVTYSLESFLG--------PRANTEDL 225
Cdd:PLN02938 139 EEYASLREFFVRSLKEGARPIdPDPNCLVSPVDGIVLRFGELKGPgtMIEQVKGFSYSVSALLGansllpmtAEGKEEKE 218

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 226 PFPPASSSDS-----------FRNQLVTREGNELYHCVIYLAPGDYHCFHSPTDWTISHRRHFPGSLMSVNPGMARWIKE 294
Cdd:PLN02938 219 EETLKDKSSKswlrvslaspkLRDPVSASPMKGLFYCVIYLGPGDYHRIHSPSDWNIEVRRHFSGRLFPVNERATRTIRN 298

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 295 LFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRIHFDRDLHTNSPRysKGSYND---LSFVTHANKEGIPMRKGEPLGEF 371
Cdd:PLN02938 299 LYVENERVVLEGEWQEGFMAMAAVGATNIGSIELFIEPELRTNRPK--KKIFNSeppEERVYEPEGCGLCLKKGDEVAVF 376

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*..
gi 126722757 372 NLGSTIVLIFEAP--------------KDFNFRLKAGQKIRFGEALG 404
Cdd:PLN02938 377 NLGSTVVLVFEAPveveplfkvldqssSDFRFCVRKGDRIRVGQALG 423
 
Name Accession Description Interval E-value
PLN02938 PLN02938
phosphatidylserine decarboxylase
 78-404 1.20e-88

phosphatidylserine decarboxylase


Pssm-ID: 178526  Cd Length: 428  Bit Score: 274.78  E-value: 1.20e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757  78 RQYE-KYRERKLEKlGLEipPKLASHWEVSLYKSVPTRLLSRACGRLNQVELPYWLRRPVYSLYIWTFGVNMTEAAVEdL 156
Cdd:PLN02938  63 RLYEdKKVEEAREK-GIE--PEFSPDTKASFLRLLPLRSISRLWGSLTSVELPVWMRPYVYKAWARAFHSNLEEAALP-L 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 157 HHYRNLSEFFRRKLKPQARPV-CGLHCVTSPSDGKILTFGQVKNS--EVEQVKGVTYSLESFLG--------PRANTEDL 225
Cdd:PLN02938 139 EEYASLREFFVRSLKEGARPIdPDPNCLVSPVDGIVLRFGELKGPgtMIEQVKGFSYSVSALLGansllpmtAEGKEEKE 218

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 226 PFPPASSSDS-----------FRNQLVTREGNELYHCVIYLAPGDYHCFHSPTDWTISHRRHFPGSLMSVNPGMARWIKE 294
Cdd:PLN02938 219 EETLKDKSSKswlrvslaspkLRDPVSASPMKGLFYCVIYLGPGDYHRIHSPSDWNIEVRRHFSGRLFPVNERATRTIRN 298

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 295 LFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRIHFDRDLHTNSPRysKGSYND---LSFVTHANKEGIPMRKGEPLGEF 371
Cdd:PLN02938 299 LYVENERVVLEGEWQEGFMAMAAVGATNIGSIELFIEPELRTNRPK--KKIFNSeppEERVYEPEGCGLCLKKGDEVAVF 376

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*..
gi 126722757 372 NLGSTIVLIFEAP--------------KDFNFRLKAGQKIRFGEALG 404
Cdd:PLN02938 377 NLGSTVVLVFEAPveveplfkvldqssSDFRFCVRKGDRIRVGQALG 423
PS_Dcarbxylase pfam02666
Phosphatidylserine decarboxylase; This is a family of phosphatidylserine decarboxylases, EC:4. ...
 162-404 2.04e-73

Phosphatidylserine decarboxylase; This is a family of phosphatidylserine decarboxylases, EC:4.1.1.65. These enzymes catalyze the reaction: Phosphatidyl-L-serine <=> phosphatidylethanolamine + CO2. Phosphatidylserine decarboxylase plays a central role in the biosynthesis of aminophospholipids by converting phosphatidylserine to phosphatidylethanolamine.


Pssm-ID: 396989 [Multi-domain]  Cd Length: 198  Bit Score: 227.93  E-value: 2.04e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757  162 LSEFFRRKLKPQARPVC-GLHCVTSPSDGKILTFGQVKNSEVEQVKGVTYSLESFLGPRAntedlpfppasssdsfrnql 240
Cdd:pfam02666   1 LNAFFTRFLRDPARPIPaGPGAVVSPADGKISEIGEIEDDSVIQVKGVTYSLRELLGDDK-------------------- 60

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757  241 vTREGNELYHCVIYLAPGDYHCFHSPTDWTISHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTGDWKHGFFSLTAVGA 320
Cdd:pfam02666  61 -LDKFKGGTFIVIYLSPFDYHRNHAPVDGTVKEVRYIPGKLLPVNPAALKEIPNLFALNERVVLVIETTDGKVAVVQVGA 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757  321 TNVGSIRIHFdrdlhtnspryskgsyndlsfvthanKEGIPMRKGEPLGEFNLGSTIVLIFEAPKDFNFRLKAGQKIRFG 400
Cdd:pfam02666 140 LNVGSIVLTV--------------------------KPGDEVKKGEELGYFKFGSTVVLLFPKGKFFEDLVEPGQKVKAG 193


                  ....
gi 126722757  401 EALG 404
Cdd:pfam02666 194 ETIG 197
PS_decarb TIGR00163
phosphatidylserine decarboxylase precursor; Phosphatidylserine decarboxylase is synthesized as ...
 148-404 7.60e-73

phosphatidylserine decarboxylase precursor; Phosphatidylserine decarboxylase is synthesized as a single chain precursor. Generation of the pyruvoyl active site from a Ser is coupled to cleavage of a Gly-Ser bond between the larger (beta) and smaller (alpha chains). It is an integral membrane protein. A closely related family, possibly also active as phosphatidylserine decarboxylase, falls under model TIGR00164. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 272936 [Multi-domain]  Cd Length: 238  Bit Score: 227.79  E-value: 7.60e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757  148 MTEAAVEDLHHYRNLSEFFRRKLKPQARPVC-GLHCVTSPSDGKILTFGQVKNSEVEQVKGVTYSLESFLGprantEDLP 226
Cdd:TIGR00163   1 LDEAEKPDLADYRSLNEFFIRPLKLERRPVDkEPNALVSPADGVISEVGIINPNQILQVKGMDYSLEELLG-----EKNP 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757  227 FppassSDSFRNQLvtregnelYHCVIYLAPGDYHCFHSPTDWTISHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTG 306
Cdd:TIGR00163  76 L-----SPYFRNGG--------FFVVTYLSPRDYHRFHSPCDCRLRKMRYFPGDLFSVNPLGLQNVPNLFVRNERVILVF 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757  307 DWKHGFFSLTAVGATNVGSIRIHFDRDLHTNSPR--YSKGSYNDLSfvthankeGIPMRKGEPLGEFNLGSTIVLIFEA- 383
Cdd:TIGR00163 143 DTEFGNMLMIPVGATNVGSIRTNFDGNIQTNPRHefTQTWTYNALG--------PVKLLKGEEMGYFELGSTVILLFEAd 214

                         250       260
                  ....*....|....*....|.
gi 126722757  384 PKDFNFRLKAGQKIRFGEALG 404
Cdd:TIGR00163 215 AFQLSAHLAVGQEVKIGELLA 235
Psd COG0688
Phosphatidylserine decarboxylase [Lipid transport and metabolism]; Phosphatidylserine ...
 112-406 1.43e-56

Phosphatidylserine decarboxylase [Lipid transport and metabolism]; Phosphatidylserine decarboxylase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440452 [Multi-domain]  Cd Length: 243  Bit Score: 185.83  E-value: 1.43e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 112 PTRLLSRACGRLNQVELPYWlrRPVYSLYIWTFGVNMTEAAVEdlhHYRNLSEFFRRKLKPQARPVC-GLHCVTSPSDGK 190
Cdd:COG0688    1 PKHLLSRLMGPIAREGWPFI--ALLIRTFIKRYGIDLSEALPS---SYTSFNDFFFRDLKPGARPIPdDPDAVVSPADGK 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 191 ILTFGQVKNSEVEQVKGVTYSLESFLGPRANTEDlpfppasssdsFRN-QLVTregnelyhcvIYLAPGDYHCFHSPTDW 269
Cdd:COG0688   76 VSQIGEIEEDRLLQAKGHPYSLEELLGDSELAEK-----------FEGgTFVS----------IFLSPFDYHRNHMPVDG 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 270 TISHRRHFPGSLMSVNPGMARwiKELFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRIHFdrdlhtnspryskgsyndl 349
Cdd:COG0688  135 TVVEVKYIPGKFLSVNPLALR--PKLFARNERVVIVIETEFGPVAVVQVGALIVRRIVTYV------------------- 193

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 126722757 350 sfvthanKEGIPMRKGEPLGEFNLGSTIVLIFEaPKDFNFRLKAGQKIRFGEALGSL 406
Cdd:COG0688  194 -------KEGDTLKKGEEMGLFKFGSTVDLLLP-KGAVEILVKPGQKVRAGETIGRL 242
 
Name Accession Description Interval E-value
PLN02938 PLN02938
phosphatidylserine decarboxylase
 78-404 1.20e-88

phosphatidylserine decarboxylase


Pssm-ID: 178526  Cd Length: 428  Bit Score: 274.78  E-value: 1.20e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757  78 RQYE-KYRERKLEKlGLEipPKLASHWEVSLYKSVPTRLLSRACGRLNQVELPYWLRRPVYSLYIWTFGVNMTEAAVEdL 156
Cdd:PLN02938  63 RLYEdKKVEEAREK-GIE--PEFSPDTKASFLRLLPLRSISRLWGSLTSVELPVWMRPYVYKAWARAFHSNLEEAALP-L 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 157 HHYRNLSEFFRRKLKPQARPV-CGLHCVTSPSDGKILTFGQVKNS--EVEQVKGVTYSLESFLG--------PRANTEDL 225
Cdd:PLN02938 139 EEYASLREFFVRSLKEGARPIdPDPNCLVSPVDGIVLRFGELKGPgtMIEQVKGFSYSVSALLGansllpmtAEGKEEKE 218

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 226 PFPPASSSDS-----------FRNQLVTREGNELYHCVIYLAPGDYHCFHSPTDWTISHRRHFPGSLMSVNPGMARWIKE 294
Cdd:PLN02938 219 EETLKDKSSKswlrvslaspkLRDPVSASPMKGLFYCVIYLGPGDYHRIHSPSDWNIEVRRHFSGRLFPVNERATRTIRN 298

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 295 LFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRIHFDRDLHTNSPRysKGSYND---LSFVTHANKEGIPMRKGEPLGEF 371
Cdd:PLN02938 299 LYVENERVVLEGEWQEGFMAMAAVGATNIGSIELFIEPELRTNRPK--KKIFNSeppEERVYEPEGCGLCLKKGDEVAVF 376

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*..
gi 126722757 372 NLGSTIVLIFEAP--------------KDFNFRLKAGQKIRFGEALG 404
Cdd:PLN02938 377 NLGSTVVLVFEAPveveplfkvldqssSDFRFCVRKGDRIRVGQALG 423
PS_Dcarbxylase pfam02666
Phosphatidylserine decarboxylase; This is a family of phosphatidylserine decarboxylases, EC:4. ...
 162-404 2.04e-73

Phosphatidylserine decarboxylase; This is a family of phosphatidylserine decarboxylases, EC:4.1.1.65. These enzymes catalyze the reaction: Phosphatidyl-L-serine <=> phosphatidylethanolamine + CO2. Phosphatidylserine decarboxylase plays a central role in the biosynthesis of aminophospholipids by converting phosphatidylserine to phosphatidylethanolamine.


Pssm-ID: 396989 [Multi-domain]  Cd Length: 198  Bit Score: 227.93  E-value: 2.04e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757  162 LSEFFRRKLKPQARPVC-GLHCVTSPSDGKILTFGQVKNSEVEQVKGVTYSLESFLGPRAntedlpfppasssdsfrnql 240
Cdd:pfam02666   1 LNAFFTRFLRDPARPIPaGPGAVVSPADGKISEIGEIEDDSVIQVKGVTYSLRELLGDDK-------------------- 60

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757  241 vTREGNELYHCVIYLAPGDYHCFHSPTDWTISHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTGDWKHGFFSLTAVGA 320
Cdd:pfam02666  61 -LDKFKGGTFIVIYLSPFDYHRNHAPVDGTVKEVRYIPGKLLPVNPAALKEIPNLFALNERVVLVIETTDGKVAVVQVGA 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757  321 TNVGSIRIHFdrdlhtnspryskgsyndlsfvthanKEGIPMRKGEPLGEFNLGSTIVLIFEAPKDFNFRLKAGQKIRFG 400
Cdd:pfam02666 140 LNVGSIVLTV--------------------------KPGDEVKKGEELGYFKFGSTVVLLFPKGKFFEDLVEPGQKVKAG 193


                  ....
gi 126722757  401 EALG 404
Cdd:pfam02666 194 ETIG 197
PS_decarb TIGR00163
phosphatidylserine decarboxylase precursor; Phosphatidylserine decarboxylase is synthesized as ...
 148-404 7.60e-73

phosphatidylserine decarboxylase precursor; Phosphatidylserine decarboxylase is synthesized as a single chain precursor. Generation of the pyruvoyl active site from a Ser is coupled to cleavage of a Gly-Ser bond between the larger (beta) and smaller (alpha chains). It is an integral membrane protein. A closely related family, possibly also active as phosphatidylserine decarboxylase, falls under model TIGR00164. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 272936 [Multi-domain]  Cd Length: 238  Bit Score: 227.79  E-value: 7.60e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757  148 MTEAAVEDLHHYRNLSEFFRRKLKPQARPVC-GLHCVTSPSDGKILTFGQVKNSEVEQVKGVTYSLESFLGprantEDLP 226
Cdd:TIGR00163   1 LDEAEKPDLADYRSLNEFFIRPLKLERRPVDkEPNALVSPADGVISEVGIINPNQILQVKGMDYSLEELLG-----EKNP 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757  227 FppassSDSFRNQLvtregnelYHCVIYLAPGDYHCFHSPTDWTISHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTG 306
Cdd:TIGR00163  76 L-----SPYFRNGG--------FFVVTYLSPRDYHRFHSPCDCRLRKMRYFPGDLFSVNPLGLQNVPNLFVRNERVILVF 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757  307 DWKHGFFSLTAVGATNVGSIRIHFDRDLHTNSPR--YSKGSYNDLSfvthankeGIPMRKGEPLGEFNLGSTIVLIFEA- 383
Cdd:TIGR00163 143 DTEFGNMLMIPVGATNVGSIRTNFDGNIQTNPRHefTQTWTYNALG--------PVKLLKGEEMGYFELGSTVILLFEAd 214

                         250       260
                  ....*....|....*....|.
gi 126722757  384 PKDFNFRLKAGQKIRFGEALG 404
Cdd:TIGR00163 215 AFQLSAHLAVGQEVKIGELLA 235
PRK03934 PRK03934
phosphatidylserine decarboxylase; Provisional
 112-406 1.09e-61

phosphatidylserine decarboxylase; Provisional


Pssm-ID: 235177 [Multi-domain]  Cd Length: 265  Bit Score: 199.79  E-value: 1.09e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 112 PTRLLSRACGRLNQVELPYWLRRPVYSLYIWTFGVNMTEaaVEDLHHYRNLSEFFRRKLKPQaRPV-CGLHCVTSPSDGK 190
Cdd:PRK03934   3 LSNALSRIFGKFAGYKFPKFIQKFINASYVKIFKIDMSE--FKPPENYKSLNALFTRSLKKP-REFdEDPNIFISPCDSL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 191 ILTFGQVKNSEVEQVKGVTYSLESFLGPRANTEDLPFppasssdSFRNqlvtregnelyhcvIYLAPGDYHCFHSPTDWT 270
Cdd:PRK03934  80 ITECGSLEEDKALQIKGMEYSIEELLGESNSELVNGF-------DYIN--------------FYLSPKDYHRYHAPCDLE 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 271 ISHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTGDWKHG-FFSLTAVGATNVGSIRIHFDRDLHTNSpryskgsynDL 349
Cdd:PRK03934 139 ILEARYIPGKLYPVNLPSLEKNKNLFVKNERVVLKCKDKKGkRLYFVFVGALNVGKMRFNFDERIQTNA---------KA 209

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 126722757 350 SFVTHANKEGIPMRKGEPLGEFNLGSTIVLIFEaPKDFNFRLKAGQKIRFGEALGSL 406
Cdd:PRK03934 210 RFIQTYEYENLKLKKGEELGNFEMGSTIVLFSQ-KGSLEFNLKAGKSVKFGESIGEI 265
PTZ00403 PTZ00403
phosphatidylserine decarboxylase; Provisional
 113-404 2.04e-59

phosphatidylserine decarboxylase; Provisional


Pssm-ID: 173594  Cd Length: 353  Bit Score: 197.00  E-value: 2.04e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 113 TRLL-----SRACGRLNQVELPYWLRRPVYSLYIWTFGVNmTEAAVEDLHHYRNLSEFFRRKLKPQARPV--CGLHCVTS 185
Cdd:PTZ00403  57 ARLLfgrtrSRITGSIFNIEIPNTYRLPIYNFLIKYMGIN-KEEIKYPIESYKSIGDFFSRYIREETRPIgdVSDYSIVS 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 186 PSDGKILTFGQVKNSEVEQVKGVTYSLESFLGprantedLPFPPASSSDSfrnqlvtregNELYHCVIYLAPGDYHCFHS 265
Cdd:PTZ00403 136 PCDSELTDYGELSSEYLENVKGVKFNVNTFLG-------SDMQKKYNDGS----------TKFFYAIFYLSPKKYHHFHA 198

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 266 PTDWTISHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRIHFDRDLHTNSPR----Y 341
Cdd:PTZ00403 199 PFNFKYKIRRHISGELFPVFQGMFKIINNLFNINERVILSGEWKGGNVYYAAISAYNVGNIKIINDEELVTNNLRtqlsY 278

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 126722757 342 SKGSYNDLSFVTHANKEgipmrKGEPLGEFNLGSTIVLIFEAPKDFNFRLKAGQKIRFGEALG 404
Cdd:PTZ00403 279 MGGDINTKIYDSYKSVE-----VGDEVGEFRMGSSIVVIFENKKNFSWNVKPNQTVSVGQRLG 336
psd PRK00044
phosphatidylserine decarboxylase; Reviewed
 111-404 7.95e-59

phosphatidylserine decarboxylase; Reviewed


Pssm-ID: 234591  Cd Length: 288  Bit Score: 193.12  E-value: 7.95e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 111 VPTRLLSRACGRLNQVELPyWLRRPVYSLYIWTFGVNMTEAAVEDLHHYRNLSEFFRRKLKPQARPVC-GLHCVTSPSDG 189
Cdd:PRK00044  13 LPKHLLTRLAGWLASSRAG-WLTTAVIRLFIKKYKVDMSEAQKPDPAAYKTFNDFFTRALKDGARPIDeDPNALVSPADG 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 190 KILTFGQVKNSEVEQVKGVTYSLESFLGpraNTEDLpfppassSDSFRN-QLVTregnelyhcvIYLAPGDYHCFHSPTD 268
Cdd:PRK00044  92 AISQLGPIEDGQIFQAKGHSYSLEALLG---GDAAL-------ADPFRNgSFAT----------IYLSPRDYHRVHMPCD 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 269 WTISHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRihfdrdlhT------NSPRY- 341
Cdd:PRK00044 152 GTLREMIYVPGDLFSVNPLTARNVPNLFARNERVVCLFDTEFGPMAQVLVGATIVGSIE--------TvwagtvTPPREg 223

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 126722757 342 --SKGSYNDlsfvthANKEGIPMRKGEPLGEFNLGSTIVLIFEAPK-DFNFRLKAGQKIRFGEALG 404
Cdd:PRK00044 224 iiKRWDYPE------AGDGAITLKKGAEMGRFKLGSTVINLFPPGKvQLAEQLQAGSVVRMGQPLA 283
Psd COG0688
Phosphatidylserine decarboxylase [Lipid transport and metabolism]; Phosphatidylserine ...
 112-406 1.43e-56

Phosphatidylserine decarboxylase [Lipid transport and metabolism]; Phosphatidylserine decarboxylase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440452 [Multi-domain]  Cd Length: 243  Bit Score: 185.83  E-value: 1.43e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 112 PTRLLSRACGRLNQVELPYWlrRPVYSLYIWTFGVNMTEAAVEdlhHYRNLSEFFRRKLKPQARPVC-GLHCVTSPSDGK 190
Cdd:COG0688    1 PKHLLSRLMGPIAREGWPFI--ALLIRTFIKRYGIDLSEALPS---SYTSFNDFFFRDLKPGARPIPdDPDAVVSPADGK 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 191 ILTFGQVKNSEVEQVKGVTYSLESFLGPRANTEDlpfppasssdsFRN-QLVTregnelyhcvIYLAPGDYHCFHSPTDW 269
Cdd:COG0688   76 VSQIGEIEEDRLLQAKGHPYSLEELLGDSELAEK-----------FEGgTFVS----------IFLSPFDYHRNHMPVDG 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 270 TISHRRHFPGSLMSVNPGMARwiKELFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRIHFdrdlhtnspryskgsyndl 349
Cdd:COG0688  135 TVVEVKYIPGKFLSVNPLALR--PKLFARNERVVIVIETEFGPVAVVQVGALIVRRIVTYV------------------- 193

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 126722757 350 sfvthanKEGIPMRKGEPLGEFNLGSTIVLIFEaPKDFNFRLKAGQKIRFGEALGSL 406
Cdd:COG0688  194 -------KEGDTLKKGEEMGLFKFGSTVDLLLP-KGAVEILVKPGQKVRAGETIGRL 242
PRK03140 PRK03140
phosphatidylserine decarboxylase; Provisional
 132-406 4.00e-32

phosphatidylserine decarboxylase; Provisional


Pssm-ID: 179544 [Multi-domain]  Cd Length: 259  Bit Score: 122.02  E-value: 4.00e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 132 LRRPVYSLYIWTFGVNMTEAAvEDLHHYRNLSEFFRRKLKPQARPV-CGLHCVTSPSDGKILTFGQVKNSEVEQVKGVTY 210
Cdd:PRK03140  30 LSSILIPSYAKVYQINQDEME-KGLKEYRTLHELFTRKLKEGKRPIdTDASSIVSPVDGVFADVGPIEDDKTFDVKGKRY 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 211 SLESFLGprantedlpfppasssdsfrNQLVTREGNELYHCVIYLAPGDYHCFHSPTDWTISH-----RRHFPgslmsVN 285
Cdd:PRK03140 109 SIAEMLG--------------------NEERAQRYAGGTYMVLYLSPSHYHRIHSPISGTVTEqfvlgRKSYP-----VN 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 286 PGMARWIKELFCHNERVV--LTGDWKHgfFSLTAVGATNVGSIRIhfdrdlhtnspryskgsyndlsfvTHANKEgipMR 363
Cdd:PRK03140 164 ALGLEYGKRPLSKNYRSVteVNSDGEH--MALVKVGAMFVNSIEL------------------------THERDT---VQ 214

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 126722757 364 KGEPLGEFNLGSTIVLIFEapKD---FNFRLKAGQKIRFGEALGSL 406
Cdd:PRK03140 215 KGEEMAYFSFGSTVVLLFE--KDmiePDQELKSGQEVRLGEKIGTR 258
PRK00723 PRK00723
phosphatidylserine decarboxylase; Provisional
 144-404 2.95e-31

phosphatidylserine decarboxylase; Provisional


Pssm-ID: 179097 [Multi-domain]  Cd Length: 297  Bit Score: 120.79  E-value: 2.95e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 144 FGVNMTEAAvEDLHHYRNLSEFFRRKLKPQARPVC-GLHCVTSPSDGKILTFGQVKNSEVEQVKGVTYSLESFLGprant 222
Cdd:PRK00723  69 FNIDMSESE-KPLSDFKSFNDFFTRKLKPEARPIDqGENILISPGDGRLLAYENIDLNSLFQVKGKTYSLKELLG----- 142

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 223 edlpfppasssdsfrNQLVTREgnelYH---CVIY-LAPGDYHCFHSPTDWTISHRRHFPGSLMSVNPGMARWIKELFCH 298
Cdd:PRK00723 143 ---------------DPELAKK----YAggtCLILrLCPTDYHRFHFPDSGICEETRKIKGHYYSVNPIALKKIFELFCE 203

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 299 NER--VVLTGDwKHGFFSLTAVGATNVGSIrihfdrdLHTNSPryskgsyndlsfvthankeGIPMRKGEPLGEFNL-GS 375
Cdd:PRK00723 204 NKRewSIFKSE-NFGDILYVEVGATCVGSI-------IQTYKP-------------------NKKVKKGDEKGYFKFgGS 256

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 126722757 376 TIVLIFEAPK-----DF--NFRLKAGQKIRFGEALG 404
Cdd:PRK00723 257 TVILFFEKNKikidaDIleQSKLGYETKVLMGESIG 292
PRK09629 PRK09629
bifunctional thiosulfate sulfurtransferase/phosphatidylserine decarboxylase; Provisional
 111-404 3.65e-30

bifunctional thiosulfate sulfurtransferase/phosphatidylserine decarboxylase; Provisional


Pssm-ID: 104071 [Multi-domain]  Cd Length: 610  Bit Score: 122.53  E-value: 3.65e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 111 VPTRLLSRACGRLNQVELpYWLRRPVYSLYIWTFGVNMTEAAVEDLHHYRNLSEFFRRKLKPQARPV-CGLHCVTSPSDG 189
Cdd:PRK09629 336 LPHHLLSRLAGCVAECRV-RWFKNAFTAWFARRYQVDMSQALVEDLTSYEHFNAFFTRALKADARPLdTTPGAILSPADG 414

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 190 KILTFGQVKNSEVEQVKGVTYSLESFLG--PRANTedlPFppasssdsfrnqlvtrEGNELyhCVIYLAPGDYHCFHSPT 267
Cdd:PRK09629 415 AISQLGPIDHGRIFQAKGHSFSVLELLGgdPKLSA---PF----------------MGGEF--ATVYLSPKDYHRVHMPL 473

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 268 DWTISHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTGDWKHGFFSLTAVGATNVGSIRIHFDRDLHTNSPRYSKGSYN 347
Cdd:PRK09629 474 AGTLREMVYVPGRIFSVNQTTAENVPELFARNERVVCLFDTERGPMAVVLVGAMIVASVETVWAGLVTPPKRELKTFSYD 553

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 126722757 348 DlsfvthANKEGIPMRKGEPLGEFNLGSTIVLIFeAPKDFNF--RLKAGQKIRFGEALG 404
Cdd:PRK09629 554 E------AARAPIHLEKGAEMGRFKLGSTAIVLF-GPNQVKWaeQLTAGSKVQMGQALA 605
PLN02964 PLN02964
phosphatidylserine decarboxylase
 146-383 1.21e-20

phosphatidylserine decarboxylase


Pssm-ID: 215520 [Multi-domain]  Cd Length: 644  Bit Score: 94.16  E-value: 1.21e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 146 VNMTEAAvEDLHHYRNLSEFFRRKLKPQARPV-CGLH--CVTSPSDGKILTFGQVKNSEVEQVKGVTYSLESFLGPRANT 222
Cdd:PLN02964 401 INMDEVK-YPLEHFKTFNEFFIRELKPGARPIaCMDNddVAVCAADCRLMAFQSVDDSTRFWIKGRKFSIKGLLGKKVHS 479

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 223 EDLPFPPasssdsfrnqlvtregnelyhCVIY-LAPGDYHCFHSPTDWTISHRRHFPGSLMSVNPgMARWIK--ELFCHN 299
Cdd:PLN02964 480 DAFLDGS---------------------LVIFrLAPQDYHRFHVPVSGVIEKFVDVPGSLYTVNP-IAVNSKycNVFTEN 537

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722757 300 ERVV-LTGDWKHGFFSLTAVGATNVGSIrihfdrdlhtnspryskgsyndlsfvTHANKEGIPMRKGEPLGEFNLG-STI 377
Cdd:PLN02964 538 KRAVcIISTAEFGKVAFVAIGATMVGSI--------------------------TFVKKEGDHVKKGDELGYFSFGgSTV 591


                 ....*.
gi 126722757 378 VLIFEA 383
Cdd:PLN02964 592 ICVFEK 597
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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