NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|23346595|ref|NP_694792|]
View 

MICOS complex subunit MIC13 precursor [Mus musculus]

Protein Classification

QIL1 domain-containing protein( domain architecture ID 11239540)

QIL1 domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
QIL1 pfam15884
MICOS complex subunit MIC13, QIL1; Mic13 (also known as Qil1) is a component of the MICOS ...
 25-106 5.94e-22

MICOS complex subunit MIC13, QIL1; Mic13 (also known as Qil1) is a component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Mic13 is required for MICOS complex stability and cristae morphology. Family members such as C19orf70/QIL1 from human are orthologous to the yeast MIC12 pfam17050.


:

Pssm-ID: 464923  Cd Length: 77  Bit Score: 82.36  E-value: 5.94e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346595    25 VYDQELLGPSDKSEAALRKAEEVVPPAMYQFSQYVCqqtgLEMPQLPTPPKIKFPnFRDSWNSGIISVMSALSVAPSKAR 104
Cdd:pfam15884   1 TYDEGLWGSSEETAELYERAKEYIPPYVDEVPKYVP----WEVPQLPSVEEIKFS-AVEYWNKGVKTSFSFLSNLPTYAK 75


                  ..
gi 23346595   105 EY 106
Cdd:pfam15884  76 EY 77
 
Name Accession Description Interval E-value
QIL1 pfam15884
MICOS complex subunit MIC13, QIL1; Mic13 (also known as Qil1) is a component of the MICOS ...
 25-106 5.94e-22

MICOS complex subunit MIC13, QIL1; Mic13 (also known as Qil1) is a component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Mic13 is required for MICOS complex stability and cristae morphology. Family members such as C19orf70/QIL1 from human are orthologous to the yeast MIC12 pfam17050.


Pssm-ID: 464923  Cd Length: 77  Bit Score: 82.36  E-value: 5.94e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346595    25 VYDQELLGPSDKSEAALRKAEEVVPPAMYQFSQYVCqqtgLEMPQLPTPPKIKFPnFRDSWNSGIISVMSALSVAPSKAR 104
Cdd:pfam15884   1 TYDEGLWGSSEETAELYERAKEYIPPYVDEVPKYVP----WEVPQLPSVEEIKFS-AVEYWNKGVKTSFSFLSNLPTYAK 75


                  ..
gi 23346595   105 EY 106
Cdd:pfam15884  76 EY 77
 
Name Accession Description Interval E-value
QIL1 pfam15884
MICOS complex subunit MIC13, QIL1; Mic13 (also known as Qil1) is a component of the MICOS ...
 25-106 5.94e-22

MICOS complex subunit MIC13, QIL1; Mic13 (also known as Qil1) is a component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Mic13 is required for MICOS complex stability and cristae morphology. Family members such as C19orf70/QIL1 from human are orthologous to the yeast MIC12 pfam17050.


Pssm-ID: 464923  Cd Length: 77  Bit Score: 82.36  E-value: 5.94e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 23346595    25 VYDQELLGPSDKSEAALRKAEEVVPPAMYQFSQYVCqqtgLEMPQLPTPPKIKFPnFRDSWNSGIISVMSALSVAPSKAR 104
Cdd:pfam15884   1 TYDEGLWGSSEETAELYERAKEYIPPYVDEVPKYVP----WEVPQLPSVEEIKFS-AVEYWNKGVKTSFSFLSNLPTYAK 75


                  ..
gi 23346595   105 EY 106
Cdd:pfam15884  76 EY 77
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH