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Conserved domains on  [gi|31982953|ref|NP_689518|]
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protein O-glucosyltransferase 1 precursor [Homo sapiens]

Protein Classification

glycosyltransferase family 90 protein( domain architecture ID 10529423)

glycosyltransferase family 90 protein similar to mammalian protein O-glucosyltransferase 1, a dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glyco_transf_90 pfam05686
Glycosyl transferase family 90; This family of glycosyl transferases are specifically ...
 49-388 1.85e-148

Glycosyl transferase family 90; This family of glycosyl transferases are specifically (mannosyl) glucuronoxylomannan/galactoxylomannan -beta 1,2-xylosyltransferases, EC:2.4.2.-.


:

Pssm-ID: 310354  Cd Length: 396  Bit Score: 425.74  E-value: 1.85e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953    49 CSSQNCSCYHGVIEEDLTPFRG-GISRKMMAEVvRRKLGTHYQITKNRLYREN-DCMFPSR----CSGVEHFILEVIGRL 122
Cdd:pfam05686   1 SSSPTCPDYFRWIHEDLEPWREtGITREMVERA-KRKAHFRYVIINGRVYVETyGESFQTRdvftIWGILQLLRKYPGRL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953   123 PDMEMVINVRDYPQVPKWMEP-----AIPVFSFSKTSEYHDIMYPAWTFWEggpavWPiyPTGLGRWDLFREDLVRSAAQ 197
Cdd:pfam05686  80 PDLELMFNCGDWPVVKKRDYRgpnanPPPLFSYCGDDDTLDIVFPDWSFWG-----WP--EVNIGRWDLLRKDLKEGNTR 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953   198 WPWKKKNSTAYFRGSRTSPE-RDPLILLSRKNPKLVDAEYTKNqawksMKDTLGKPAAKDVHLVDHCKYKYLFNFRGVAA 276
Cdd:pfam05686 153 VKWEDREPYAYWRGNPSVAEtRLELVKCNRSNPEDWDARLTNQ-----DWDTEYRPGFKHSSLVDQCTHKYKIYIEGVAW 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953   277 SFRFKHLFLCGSLVFHVGDEWLEFFYPQLKPWVHYIPVKT--DLSNVQELLQFVKANDDVAQEIAERGSQFIRNHLQMDD 354
Cdd:pfam05686 228 SVSLKYILACDSLVLHVGPEYYDFFYRGLKPWVHYWPIKSddDCRDLKEAVDWGNAHDDEAQKIAERGSEFIRENLKMDD 307

                         330       340       350
                  ....*....|....*....|....*....|....
gi 31982953   355 ITCYWENLLSEYSKFLSYNVTRRKGYDQIIPKML 388
Cdd:pfam05686 308 VYDYMFHLLTEYAKLLKYKPTVPKGAVEVCPESM 341
 
Name Accession Description Interval E-value
Glyco_transf_90 pfam05686
Glycosyl transferase family 90; This family of glycosyl transferases are specifically ...
 49-388 1.85e-148

Glycosyl transferase family 90; This family of glycosyl transferases are specifically (mannosyl) glucuronoxylomannan/galactoxylomannan -beta 1,2-xylosyltransferases, EC:2.4.2.-.


Pssm-ID: 310354  Cd Length: 396  Bit Score: 425.74  E-value: 1.85e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953    49 CSSQNCSCYHGVIEEDLTPFRG-GISRKMMAEVvRRKLGTHYQITKNRLYREN-DCMFPSR----CSGVEHFILEVIGRL 122
Cdd:pfam05686   1 SSSPTCPDYFRWIHEDLEPWREtGITREMVERA-KRKAHFRYVIINGRVYVETyGESFQTRdvftIWGILQLLRKYPGRL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953   123 PDMEMVINVRDYPQVPKWMEP-----AIPVFSFSKTSEYHDIMYPAWTFWEggpavWPiyPTGLGRWDLFREDLVRSAAQ 197
Cdd:pfam05686  80 PDLELMFNCGDWPVVKKRDYRgpnanPPPLFSYCGDDDTLDIVFPDWSFWG-----WP--EVNIGRWDLLRKDLKEGNTR 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953   198 WPWKKKNSTAYFRGSRTSPE-RDPLILLSRKNPKLVDAEYTKNqawksMKDTLGKPAAKDVHLVDHCKYKYLFNFRGVAA 276
Cdd:pfam05686 153 VKWEDREPYAYWRGNPSVAEtRLELVKCNRSNPEDWDARLTNQ-----DWDTEYRPGFKHSSLVDQCTHKYKIYIEGVAW 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953   277 SFRFKHLFLCGSLVFHVGDEWLEFFYPQLKPWVHYIPVKT--DLSNVQELLQFVKANDDVAQEIAERGSQFIRNHLQMDD 354
Cdd:pfam05686 228 SVSLKYILACDSLVLHVGPEYYDFFYRGLKPWVHYWPIKSddDCRDLKEAVDWGNAHDDEAQKIAERGSEFIRENLKMDD 307

                         330       340       350
                  ....*....|....*....|....*....|....
gi 31982953   355 ITCYWENLLSEYSKFLSYNVTRRKGYDQIIPKML 388
Cdd:pfam05686 308 VYDYMFHLLTEYAKLLKYKPTVPKGAVEVCPESM 341
CAP10 smart00672
Putative lipopolysaccharide-modifying enzyme;
121-372 7.81e-93

Putative lipopolysaccharide-modifying enzyme;


Pssm-ID: 214773  Cd Length: 256  Bit Score: 278.92  E-value: 7.81e-93
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953    121 RLPDMEMVINVRDYPQVPK------WMEPAIPVFSFSKTSEYHDIMYPAWTFWEGgpavwpiYPTGLGR-WDLFREDLVR 193
Cdd:smart00672   1 RVPDLELMFNCRDWPLINKksfasyNQHAPPPLFSYCGSDEYLDIVFPDWSFWAG-------WPEVNGRpWDKDLMELEE 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953    194 SAAQWPWKKKNSTAYFRGSRTSP-ERDPLILLSRKNPKLVDAEYTKNQAWKSMKDTLGKPAAKDVHLVDHCKYKYLFNFR 272
Cdd:smart00672  74 GNKRTKWSDKNAYAYWRGNPTVAsERLDLIKCNQSSPELVNARITIQDWPGKCDGEEDAPGFKKSPLEEQCKHKYKINIE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953    273 GVAASFRFKHLFLCGSLVFHVGDEWLEFFYPQLKPWVHYIPVKTDLS--NVQELLQFVKANDDVAQEIAERGSQFIRNHL 350
Cdd:smart00672 154 GVAWSVRLKYILACDSVVLKVKPEYYEFFSRGLQPWVHYWPIKSDLScrELKEAVDWGNEHDKKAQEIGKRGSEFIQQNL 233

                          250       260
                   ....*....|....*....|..
gi 31982953    351 QMDDITCYWENLLSEYSKFLSY 372
Cdd:smart00672 234 SMEDVYDYMFHLLQEYAKLLKY 255
 
Name Accession Description Interval E-value
Glyco_transf_90 pfam05686
Glycosyl transferase family 90; This family of glycosyl transferases are specifically ...
 49-388 1.85e-148

Glycosyl transferase family 90; This family of glycosyl transferases are specifically (mannosyl) glucuronoxylomannan/galactoxylomannan -beta 1,2-xylosyltransferases, EC:2.4.2.-.


Pssm-ID: 310354  Cd Length: 396  Bit Score: 425.74  E-value: 1.85e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953    49 CSSQNCSCYHGVIEEDLTPFRG-GISRKMMAEVvRRKLGTHYQITKNRLYREN-DCMFPSR----CSGVEHFILEVIGRL 122
Cdd:pfam05686   1 SSSPTCPDYFRWIHEDLEPWREtGITREMVERA-KRKAHFRYVIINGRVYVETyGESFQTRdvftIWGILQLLRKYPGRL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953   123 PDMEMVINVRDYPQVPKWMEP-----AIPVFSFSKTSEYHDIMYPAWTFWEggpavWPiyPTGLGRWDLFREDLVRSAAQ 197
Cdd:pfam05686  80 PDLELMFNCGDWPVVKKRDYRgpnanPPPLFSYCGDDDTLDIVFPDWSFWG-----WP--EVNIGRWDLLRKDLKEGNTR 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953   198 WPWKKKNSTAYFRGSRTSPE-RDPLILLSRKNPKLVDAEYTKNqawksMKDTLGKPAAKDVHLVDHCKYKYLFNFRGVAA 276
Cdd:pfam05686 153 VKWEDREPYAYWRGNPSVAEtRLELVKCNRSNPEDWDARLTNQ-----DWDTEYRPGFKHSSLVDQCTHKYKIYIEGVAW 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953   277 SFRFKHLFLCGSLVFHVGDEWLEFFYPQLKPWVHYIPVKT--DLSNVQELLQFVKANDDVAQEIAERGSQFIRNHLQMDD 354
Cdd:pfam05686 228 SVSLKYILACDSLVLHVGPEYYDFFYRGLKPWVHYWPIKSddDCRDLKEAVDWGNAHDDEAQKIAERGSEFIRENLKMDD 307

                         330       340       350
                  ....*....|....*....|....*....|....
gi 31982953   355 ITCYWENLLSEYSKFLSYNVTRRKGYDQIIPKML 388
Cdd:pfam05686 308 VYDYMFHLLTEYAKLLKYKPTVPKGAVEVCPESM 341
CAP10 smart00672
Putative lipopolysaccharide-modifying enzyme;
121-372 7.81e-93

Putative lipopolysaccharide-modifying enzyme;


Pssm-ID: 214773  Cd Length: 256  Bit Score: 278.92  E-value: 7.81e-93
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953    121 RLPDMEMVINVRDYPQVPK------WMEPAIPVFSFSKTSEYHDIMYPAWTFWEGgpavwpiYPTGLGR-WDLFREDLVR 193
Cdd:smart00672   1 RVPDLELMFNCRDWPLINKksfasyNQHAPPPLFSYCGSDEYLDIVFPDWSFWAG-------WPEVNGRpWDKDLMELEE 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953    194 SAAQWPWKKKNSTAYFRGSRTSP-ERDPLILLSRKNPKLVDAEYTKNQAWKSMKDTLGKPAAKDVHLVDHCKYKYLFNFR 272
Cdd:smart00672  74 GNKRTKWSDKNAYAYWRGNPTVAsERLDLIKCNQSSPELVNARITIQDWPGKCDGEEDAPGFKKSPLEEQCKHKYKINIE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 31982953    273 GVAASFRFKHLFLCGSLVFHVGDEWLEFFYPQLKPWVHYIPVKTDLS--NVQELLQFVKANDDVAQEIAERGSQFIRNHL 350
Cdd:smart00672 154 GVAWSVRLKYILACDSVVLKVKPEYYEFFSRGLQPWVHYWPIKSDLScrELKEAVDWGNEHDKKAQEIGKRGSEFIQQNL 233

                          250       260
                   ....*....|....*....|..
gi 31982953    351 QMDDITCYWENLLSEYSKFLSY 372
Cdd:smart00672 234 SMEDVYDYMFHLLQEYAKLLKY 255
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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