|
Name |
Accession |
Description |
Interval |
E-value |
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
84-1618 |
8.32e-132 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 456.01 E-value: 8.32e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 84 VTNITSSIMqRVSTDHLPKVIVT--EEYANEKELV--AASLSKSSNF-VGVVFKDT----------MSYELRFFPEMI-- 146
Cdd:TIGR01257 502 IFNITDRFL-RLANQYLECLVLDkfESYDDEVQLTqrALSLLEENRFwAGVVFPDMypwtsslpphVKYKIRMDIDVVek 580
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 147 --PVSSIYMNSREGCSKTCDAAQYWSlGFTVLQASIDAAI----IQLKTNVSVWSELESTKAVIMGEAAVVEIDTFPrgv 220
Cdd:TIGR01257 581 tnKIKDRYWDSGPRADPVEDFRYIWG-GFAYLQDMVEQGItrsqMQAEPPVGIYLQQMPYPCFVDDSFMIILNRCFP--- 656
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 221 ilIYLVIAFSPFGYFLAIHIVAEKEKKLKEFLKIMGLHDTAFWLSWVLLYASLIFLMSLLMAVIATASSLFPQSSSIVIF 300
Cdd:TIGR01257 657 --IFMVLAWIYSVSMTVKSIVLEKELRLKETLKNQGVSNAVIWCTWFLDSFSIMSMSIFLLTIFIMHGRILHYSDPFILF 734
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 301 LLFFLYGLSSVFFALMLTPLFKKSKHVGVVEFFVTVVFGFVGLLIVL----IESFPRSLVWLFSPLcqcAFLIGIAQVMH 376
Cdd:TIGR01257 735 LFLLAFSTATIMQCFLLSTFFSKASLAAACSGVIYFTLYLPHILCFAwqdrMTADLKTAVSLLSPV---AFGFGTEYLVR 811
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 377 LEDFNEGALFSNLTEGP-----YPLIITIIMLALDSVFYVLLAVYLDQVIPGEFGLRRSSLYFLKPSYWSKnkrnykelS 451
Cdd:TIGR01257 812 FEEQGLGLQWSNIGNSPlegdeFSFLLSMKMMLLDAALYGLLAWYLDQVFPGDYGTPLPWYFLLQESYWLG--------G 883
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 452 EGNINGNISLNEIVEPVSSEFIGKEaiRISGIQKSYRKK----------TENV---------EALRNLSFDIYEGQITAL 512
Cdd:TIGR01257 884 EGCSTREERALEKTEPLTEEMEDPE--HPEGINDSFFERelpglvpgvcVKNLvkifepsgrPAVDRLNITFYENQITAF 961
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 513 LGHSGTGKSTLMNILCGLCPPSDGFASIYGhrvSEIDEMFEA-RKMIGICPQSDINFDVLTVEENLSILASIKGIPANNI 591
Cdd:TIGR01257 962 LGHNGAGKTTTLSILTGLLPPTSGTVLVGG---KDIETNLDAvRQSLGMCPQHNILFHHLTVAEHILFYAQLKGRSWEEA 1038
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 592 IQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTH 671
Cdd:TIGR01257 1039 QLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKYRSGRTIIMSTH 1118
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 672 FMDEADILADRKAVISQGMLKCVGSSIFLKSKWGIGYRLSMY------------IDRYCATES----------------- 722
Cdd:TIGR01257 1119 HMDEADLLGDRIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVrkmkniqsqrggCEGTCSCTSkgfstrcparvdeitpe 1198
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 723 ---------LSSLVRQHIPAAALLQQNDQQLVYSLPFKDMDK--FSGLFSALD-IHSNLGVISYGVSMTTLEDVFLKLEV 790
Cdd:TIGR01257 1199 qvldgdvneLMDLVYHHVPEAKLVECIGQELIFLLPNKNFKQraYASLFRELEeTLADLGLSSFGISDTPLEEIFLKVTE 1278
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 791 EAEIDQAdYSVFTQQPREE-------ETDSKSFDEMEQSLLILS----------------ETKASSVST---MSLWKQQV 844
Cdd:TIGR01257 1279 DADSGSL-FAGGAQQKRENanlrhpcSGPTEKAGQTPQASHTCSpgqpaahpegqpppepEDPGVPLNTgarLILQHVQA 1357
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 845 STIAKFHFLSLKRESKSVRAVLLLLLIFFAVQI-----------------FMFFLHHSFKNAVVP----IKLVPDLYFLK 903
Cdd:TIGR01257 1358 LLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLsiiippfgeypaltlhpWMYGQQYTFFSMDEPnsehLEVLADVLLNK 1437
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 904 PG------------------------------------------DKPH-------KYKTSLL------------------ 916
Cdd:TIGR01257 1438 PGfgnrclkeewlpeypcgnstpwktpsvspnithlfqkqkwtaAHPSpscrcstREKLTMLpecpegagglpppqrtqr 1517
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 917 ----LQNSTDSDINGLI--------------EFFAHQN-------------------IMVAMFNDSDY---VSAAPHS-- 954
Cdd:TIGR01257 1518 steiLQDLTDRNISDFLvktypalirsslksKFWVNEQryggisiggklpaipitgeALVGFLSDLGQmmnVSGGPVTre 1597
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 955 ------AALNVVRSEKDyvFSAVFNSTMVYCLPVMMNIISNYYL------------YHLNVTEAIQTWSTPFIQEITDIV 1016
Cdd:TIGR01257 1598 askempDFLKHLETEDN--IKVWFNNKGWHALVSFLNVAHNAILraslpkdrdpeeYGITVISQPLNLTKEQLSEITVLT 1675
|
1210 1220 1230 1240 1250 1260 1270 1280
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1017 FKIElyfqaALLGIIV----TAMPPYFAMENAENHKIKAYTQLKLSGLLPSAYWVGQAVVDIPLFFVVLILMLGSLFAFH 1092
Cdd:TIGR01257 1676 TSVD-----AVVAICVifamSFVPASFVLYLIQERVNKAKHLQFISGVSPTTYWLTNFLWDIMNYAVSAGLVVGIFIGFQ 1750
|
1290 1300 1310 1320 1330 1340 1350 1360
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1093 HGLYFYPAKFLAVVFCLIAYVPSVILFTYIASFTFkkilntkEFWSFIYsvTALACVAI------TETTFFLQY------ 1160
Cdd:TIGR01257 1751 KKAYTSPENLPALVALLMLYGWAVIPMMYPASFLF-------DVPSTAY--VALSCANLfiginsSAITFVLELfennrt 1821
|
1370 1380 1390 1400 1410 1420 1430 1440
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1161 ---------AVTAVFHYtFCIAIPIYPL-LGCLISFIKGSWKNmpknENTYNP--WDRL---LVAVIMPYLQCILWIFLL 1225
Cdd:TIGR01257 1822 llrfnamlrKLLIVFPH-FCLGRGLIDLaLSQAVTDVYAQFGE----EHSANPfqWDLIgknLVAMAVEGVVYFLLTLLI 1896
|
1450 1460 1470 1480 1490 1500 1510 1520
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1226 QHYekihggrsirkdpFF--RALSQKAKnkkfpEPPIneDEDEDVKAERLKVkeLMGcqcceekpaimvcnlhkeyDDKK 1303
Cdd:TIGR01257 1897 QHH-------------FFlsRWIAEPAK-----EPIF--DEDDDVAEERQRI--ISG-------------------GNKT 1935
|
1530 1540 1550 1560 1570 1580 1590 1600
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1304 DFLHSRKTTKV-------ATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESiKCM 1376
Cdd:TIGR01257 1936 DILRLNELTKVysgtsspAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTNISDVH-QNM 2014
|
1610 1620 1630 1640 1650 1660 1670 1680
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1377 GYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLL 1456
Cdd:TIGR01257 2015 GYCPQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLL 2094
|
1690 1700 1710 1720 1730 1740 1750 1760
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1457 DEPSTGMDPRAKQHMWRAIRTAFKnKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKD 1536
Cdd:TIGR01257 2095 DEPTTGMDPQARRMLWNTIVSIIR-EGRAVVLTSHSMEECEALCTRLAIMVKGAFQCLGTIQHLKSKFGDGYIVTMKIKS 2173
|
1770 1780 1790 1800 1810 1820 1830 1840
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1537 WIENL--EIDRLQREIQYIFPNASRQESFSSILAFKIPKedvQSLSQSFAKLEEAKRTFAIEEYSFSQATLEQVFVELTK 1614
Cdd:TIGR01257 2174 PKDDLlpDLNPVEQFFQGNFPGSVQRERHYNMLQFQVSS---SSLARIFQLLISHKDSLLIEEYSVTQTTLDQVFVNFAK 2250
|
....
gi 146134400 1615 EQEE 1618
Cdd:TIGR01257 2251 QQTE 2254
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
478-701 |
2.23e-84 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 275.54 E-value: 2.23e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTENveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEidEMFEARKM 557
Cdd:cd03263 1 LQIRNLTKTYKKGTKP--AVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRT--DRKAARQS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:cd03263 77 LGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSSIFLK 701
Cdd:cd03263 157 LDEPTSGLDPASRRAIWDLILEVRKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
1290-1521 |
7.45e-82 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 268.22 E-value: 7.45e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYddkkdflhsRKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYgSHSSED 1369
Cdd:cd03263 1 LQIRNLTKTY---------KKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGY-SIRTDR 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 DESIKCMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLG 1449
Cdd:cd03263 71 KAARQSLGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIG 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146134400 1450 NPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNkkRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLK 1521
Cdd:cd03263 151 GPSVLLLDEPTSGLDPASRRAIWDLILEVRKG--RSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
1290-1524 |
4.09e-69 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 232.26 E-value: 4.09e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKkdflhsrkttkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGdyGSHSSED 1369
Cdd:COG1131 1 IEVRGLTKRYGDK-----------TALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVL--GEDVARD 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 DESIK-CMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSML 1448
Cdd:COG1131 68 PAEVRrRIGYVPQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALL 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 1449 GNPQVTLLDEPSTGMDPRAKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKF 1524
Cdd:COG1131 148 HDPELLILDEPTSGLDPEARRELWELLR-ELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKARL 222
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
478-696 |
1.14e-68 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 231.11 E-value: 1.14e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEmfEARKM 557
Cdd:COG1131 1 IEVRGLTKRYGDKT----ALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPA--EVRRR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:COG1131 75 IGYVPQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLI 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLKYRKANRVTVF-STHFMDEADILADRKAVISQGMLKCVGS 696
Cdd:COG1131 155 LDEPTSGLDPEARRELWELLRELAAEGKTVLlSTHYLEEAERLCDRVAIIDKGRIVADGT 214
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
478-691 |
9.04e-56 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 191.46 E-value: 9.04e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVseIDEMFEARKM 557
Cdd:cd03230 1 IEVRNLSKRYGKKT----ALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDI--KKEPEEVKRR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLsilasikgipanniiqevqkvlldldmqaikdnqakKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:cd03230 75 IGYLPEEPSLYENLTVRENL------------------------------------KLSGGMKQRLALAQALLHDPELLI 118
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLKYRKANRVTVF-STHFMDEADILADRKAVISQGML 691
Cdd:cd03230 119 LDEPTSGLDPESRREFWELLRELKKEGKTILlSSHILEEAERLCDRVAILNNGRI 173
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
1290-1526 |
1.35e-55 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 193.92 E-value: 1.35e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKKdflhsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSsED 1369
Cdd:COG4555 2 IEVENLSKKYGKVP-----------ALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRK-EP 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 DESIKCMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLG 1449
Cdd:COG4555 70 REARRQIGVLPDERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVH 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 1450 NPQVTLLDEPSTGMDPRAKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGK 1526
Cdd:COG4555 150 DPKVLLLDEPTNGLDVMARRLLREILR-ALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGE 225
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
1290-1521 |
2.46e-54 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 189.12 E-value: 2.46e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKkdflhsrkttkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYgSHSSED 1369
Cdd:cd03265 1 IEVENLVKKYGDF-----------EAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGH-DVVREP 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 DESIKCMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLG 1449
Cdd:cd03265 69 REVRRRIGIVFQDLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVH 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146134400 1450 NPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLK 1521
Cdd:cd03265 149 RPEVLFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEELK 220
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
1314-1613 |
5.63e-54 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 191.45 E-value: 5.63e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1314 VATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGShSSEDDESIKCMGYCPQTNPLWPDLTLQE 1393
Cdd:TIGR01188 7 KAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDV-VREPRKVRRSIGIVPQYASVDEDLTGRE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1394 HFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWR 1473
Cdd:TIGR01188 86 NLEMMGRLYGLPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTRRAIWD 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1474 AIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGyFLEIKLKDWIE-NLEIDRLQREIQY 1552
Cdd:TIGR01188 166 YIR-ALKEEGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRRLGKD-TLESRPRDIQSlKVEVSMLIAELGE 243
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146134400 1553 IFPNASRQESFSSILAFKIPKEDvqslSQSFAKLEEAKRT-FAIEEYSFSQATLEQVFVELT 1613
Cdd:TIGR01188 244 TGLGLLAVTVDSDRIKILVPDGD----ETVPEIVEAAIRNgIRIRSISTERPSLDDVFLKLT 301
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
478-696 |
1.71e-50 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 179.28 E-value: 1.71e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKktenVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEmfEARKM 557
Cdd:COG4555 2 IEVENLSKKYGK----VPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPR--EARRQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:COG4555 76 IGVLPDERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLK-YRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGS 696
Cdd:COG4555 156 LDEPTNGLDVMARRLLREILRaLKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGS 215
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
478-695 |
7.39e-50 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 176.23 E-value: 7.39e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKtenvEALRNLSFDIYEGqITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEidEMFEARKM 557
Cdd:cd03264 1 LQLENLTKRYGKK----RALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLK--QPQKLRRR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQsDINF-DVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKIL 636
Cdd:cd03264 74 IGYLPQ-EFGVyPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSIL 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 637 LLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVG 695
Cdd:cd03264 153 IVDEPTAGLDPEERIRFRNLLSELGEDRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
1292-1511 |
8.90e-50 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 174.51 E-value: 8.90e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1292 VCNLHKEYDDKKdflhsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdYGSHSSEDDE 1371
Cdd:cd03230 3 VRNLSKRYGKKT-----------ALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKV--LGKDIKKEPE 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1372 SIK-CMGYCPQTNPLWPDLTLQEHFeiygavkgmspgdmkevisritkaldlkehlqktvkKLPAGIKRKLCFALSMLGN 1450
Cdd:cd03230 70 EVKrRIGYLPEEPSLYENLTVRENL------------------------------------KLSGGMKQRLALAQALLHD 113
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 1451 PQVTLLDEPSTGMDPRAKQHMWRAIRTaFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:cd03230 114 PELLILDEPTSGLDPESRREFWELLRE-LKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
489-701 |
1.62e-49 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 175.64 E-value: 1.62e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 489 KKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEidEMFEARKMIGICPQSDINF 568
Cdd:cd03265 8 KKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVR--EPREVRRRIGIVFQDLSVD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 569 DVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPC 648
Cdd:cd03265 86 DELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGLDPQ 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 649 SRHIVWNLL-KYRKANRVTVF-STHFMDEADILADRKAVISQGMLKCVGSSIFLK 701
Cdd:cd03265 166 TRAHVWEYIeKLKEEFGMTILlTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEELK 220
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1292-1618 |
2.17e-46 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 169.13 E-value: 2.17e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1292 VCNLHKEYDDKKdflhsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGdyGSHSSEDDe 1371
Cdd:COG4152 4 LKGLTKRFGDKT-----------AVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWD--GEPLDPED- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1372 sIKCMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNP 1451
Cdd:COG4152 70 -RRRIGYLPEERGLYPKMKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDP 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1452 QVTLLDEPSTGMDPRAKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGYFlE 1531
Cdd:COG4152 149 ELLILDEPFSGLDPVNVELLKDVIR-ELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQFGRNTL-R 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1532 IKLK---DWIENLeidrlqreiqyifPNASRQESFSSILAFKIPKE-DVQSLsqsfakLEEAKRTFAIEEYSFSQATLEQ 1607
Cdd:COG4152 227 LEADgdaGWLRAL-------------PGVTVVEEDGDGAELKLEDGaDAQEL------LRALLARGPVREFEEVRPSLNE 287
|
330
....*....|.
gi 146134400 1608 VFVELTKEQEE 1618
Cdd:COG4152 288 IFIEVVGEKAE 298
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1289-1545 |
7.63e-46 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 168.73 E-value: 7.63e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1289 AIMVCNLHKEYDDK----------KDFLHSRKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGkif 1358
Cdd:COG4586 1 IIEVENLSKTYRVYekepglkgalKGLFRREYREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSG--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1359 lgdygshsseddeSIKCMGYCP----------------QTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDL 1422
Cdd:COG4586 78 -------------EVRVLGYVPfkrrkefarrigvvfgQRSQLWWDLPAIDSFRLLKAIYRIPDAEYKKRLDELVELLDL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1423 KEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAfkNKKRAA--LLTTHYMEEAEAVC 1500
Cdd:COG4586 145 GELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEY--NRERGTtiLLTSHDMDDIEALC 222
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 146134400 1501 DRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIENLEIDR 1545
Cdd:COG4586 223 DRVIVIDHGRIIYDGSLEELKERFGPYKTIVLELAEPVPPLELPR 267
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
1312-1515 |
8.70e-44 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 158.60 E-value: 8.70e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1312 TKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDygshSSEDDESIKCMGYCPQTNPLWPDLTL 1391
Cdd:cd03269 12 RVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDG----KPLDIAARNRIGYLPEERGLYPKMKV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1392 QEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHM 1471
Cdd:cd03269 88 IDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGLDPVNVELL 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 146134400 1472 WRAIRTaFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIG 1515
Cdd:cd03269 168 KDVIRE-LARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
486-689 |
1.50e-43 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 158.01 E-value: 1.50e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 486 SYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEiDEMFEARKMIGICPQsd 565
Cdd:cd03225 6 SFSYPDGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTK-LSLKELRRKVGLVFQ-- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 566 iNFDV----LTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEP 641
Cdd:cd03225 83 -NPDDqffgPTVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEP 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 146134400 642 TAGMDPCSRHIVWNLLKYRKANRVT-VFSTHFMDEADILADRKAVISQG 689
Cdd:cd03225 162 TAGLDPAGRRELLELLKKLKAEGKTiIIVTHDLDLLLELADRVIVLEDG 210
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
478-695 |
2.11e-43 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 157.91 E-value: 2.11e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEidEMFEARKM 557
Cdd:cd03266 2 ITADALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVK--EPAEARRR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:cd03266 80 LGFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLL 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLK-YRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVG 695
Cdd:cd03266 160 LDEPTTGLDVMATRALREFIRqLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
478-696 |
1.37e-42 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 155.95 E-value: 1.37e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTEnveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEiDEMFEARKM 557
Cdd:COG1122 1 IELENLSFSYPGGTP---ALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITK-KNLRELRRK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQsdiNFDV----LTVEE-------NLsilasikGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKlsVG 626
Cdd:COG1122 77 VGLVFQ---NPDDqlfaPTVEEdvafgpeNL-------GLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQR--VA 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 627 IA-VLG-NPKILLLDEPTAGMDPCSRHIVWNLLK-YRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGS 696
Cdd:COG1122 145 IAgVLAmEPEVLVLDEPTAGLDPRGRRELLELLKrLNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGT 217
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
478-691 |
1.58e-42 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 155.07 E-value: 1.58e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGhrvSEIDEMFEARKM 557
Cdd:cd03268 1 LKTNDLTKTYGKKR----VLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDG---KSYQKNIEALRR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSILASIKGIPANNIiqevQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:cd03268 74 IGALIEAPGFYPNLTARENLRLLARLLGIRKKRI----DEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLI 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLKYRKANRVTVF-STHFMDEADILADRKAVISQGML 691
Cdd:cd03268 150 LDEPTNGLDPDGIKELRELILSLRDQGITVLiSSHLLSEIQKVADRIGIINKGKL 204
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
478-689 |
1.57e-41 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 152.26 E-value: 1.57e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEA--- 554
Cdd:cd03255 1 IELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAafr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 555 RKMIGICPQSdinF---DVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLG 631
Cdd:cd03255 81 RRHIGFVFQS---FnllPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALAN 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 632 NPKILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADiLADRKAVISQG 689
Cdd:cd03255 158 DPKIILADEPTGNLDSETGKEVMELLRelNKEAGTTIVVVTHDPELAE-YADRIIELRDG 216
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
478-687 |
3.83e-41 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 151.47 E-value: 3.83e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSeidemfEARKM 557
Cdd:cd03293 1 LEVRNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVT------GPGPD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:cd03293 75 RGYVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADILADRKAVIS 687
Cdd:cd03293 155 LDEPFSALDALTREQLQEELLdiWRETGKTVLLVTHDIDEAVFLADRVVVLS 206
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
1290-1515 |
9.55e-41 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 150.21 E-value: 9.55e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKKdflhsrkTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHsSED 1369
Cdd:cd03266 2 ITADALTKRFRDVK-------KTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVV-KEP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 DESIKCMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLG 1449
Cdd:cd03266 74 AEARRRLGFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVH 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 1450 NPQVTLLDEPSTGMDPRAKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIG 1515
Cdd:cd03266 154 DPPVLLLDEPTTGLDVMATRALREFIR-QLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
1290-1511 |
5.52e-40 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 148.63 E-value: 5.52e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYD----------DKKDFLHSRKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFL 1359
Cdd:cd03267 1 IEVSNLSKSYRvyskepgligSLKSLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1360 GDYgSHSSEDDESIKCMGYC-PQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIK 1438
Cdd:cd03267 81 AGL-VPWKRRKKFLRRIGVVfGQKTQLWWDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQR 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1439 RKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:cd03267 160 MRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRL 232
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
1294-1512 |
8.21e-40 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 147.34 E-value: 8.21e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYDDKKdflhsrkttkvATKYISFCVKKGeILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYgSHSSEDDESI 1373
Cdd:cd03264 5 NLTKRYGKKR-----------ALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQ-DVLKQPQKLR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1374 KCMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQV 1453
Cdd:cd03264 72 RRIGYLPQEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSI 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 1454 TLLDEPSTGMDPRAkqhmwraiRTAFKN------KKRAALLTTHYMEEAEAVCDRVAIMVSGQLR 1512
Cdd:cd03264 152 LIVDEPTAGLDPEE--------RIRFRNllselgEDRIVILSTHIVEDVESLCNQVAVLNKGKLV 208
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
475-691 |
9.87e-40 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 147.50 E-value: 9.87e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 475 KEAIRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEA 554
Cdd:COG1136 2 SPLLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 555 ---RKMIGICPQSdIN-FDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVL 630
Cdd:COG1136 82 rlrRRHIGFVFQF-FNlLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALV 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 631 GNPKILLLDEPTAGMDPCSRHIVWNLLKY--RKANRVTVFSTHFMDEADIlADRKAVISQGML 691
Cdd:COG1136 161 NRPKLILADEPTGNLDSKTGEEVLELLRElnRELGTTIVMVTHDPELAAR-ADRVIRLRDGRI 222
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
478-688 |
2.24e-38 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 143.00 E-value: 2.24e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARkm 557
Cdd:COG4133 3 LEAENLSCRRGERL----LFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDYRRR-- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSILASIKGIPANNIiqEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:COG4133 77 LAYLGHADGLKPELTVRENLRFWAALYGLRADRE--AIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLK-YRKANRVTVFSTHfmDEADILADRKAVISQ 688
Cdd:COG4133 155 LDEPFTALDAAGVALLAELIAaHLARGGAVLLTTH--QPLELAAARVLDLGD 204
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
479-689 |
6.07e-38 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 139.69 E-value: 6.07e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 479 RISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDeMFEARKMI 558
Cdd:cd00267 1 EIENLSFRYGGRT----ALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLP-LEELRRRI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 559 GICPQsdinfdvltveenlsilasikgipanniiqevqkvlldldmqaikdnqakkLSGGQKRKLSVGIAVLGNPKILLL 638
Cdd:cd00267 76 GYVPQ---------------------------------------------------LSGGQRQRVALARALLLNPDLLLL 104
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 146134400 639 DEPTAGMDPCSRHIVWNLLKYRKANRVTV-FSTHFMDEADILADRKAVISQG 689
Cdd:cd00267 105 DEPTSGLDPASRERLLELLRELAEEGRTViIVTHDPELAELAADRVIVLKDG 156
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1288-1510 |
4.52e-37 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 142.64 E-value: 4.52e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1288 PAIMVCNLHKEYDDKkdflhsrkttkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSS 1367
Cdd:PRK13537 6 APIDFRNVEKRYGDK-----------LVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1368 EDDESIKcMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSM 1447
Cdd:PRK13537 75 ARHARQR-VGVVPQFDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARAL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1448 LGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKrAALLTTHYMEEAEAVCDRVAIMVSGQ 1510
Cdd:PRK13537 154 VNDPDVLVLDEPTTGLDPQARHLMWERLRSLLARGK-TILLTTHFMEEAERLCDRLCVIEEGR 215
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
477-689 |
1.04e-36 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 139.84 E-value: 1.04e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEidemfeARK 556
Cdd:COG1116 7 ALELRGVSKRFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTG------PGP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKlsVGIA--VLGNPK 634
Cdd:COG1116 81 DRGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQR--VAIAraLANDPE 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 635 ILLLDEPTAGMDPCSRHIVWN-LLKYRKANRVTV-FSTHFMDEADILADRKAVISQG 689
Cdd:COG1116 159 VLLMDEPFGALDALTRERLQDeLLRLWQETGKTVlFVTHDVDEAVFLADRVVVLSAR 215
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1289-1509 |
1.11e-36 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 142.66 E-value: 1.11e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1289 AIMVCNLHKEYDDKkdflhsrkttkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI-FLGDygSHSS 1367
Cdd:PRK13536 41 AIDLAGVSKSYGDK-----------AVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKItVLGV--PVPA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1368 EDDESIKCMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSM 1447
Cdd:PRK13536 108 RARLARARIGVVPQFDNLDLEFTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARAL 187
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146134400 1448 LGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKrAALLTTHYMEEAEAVCDRVAIMVSG 1509
Cdd:PRK13536 188 INDPQLLILDEPTTGLDPHARHLIWERLRSLLARGK-TILLTTHFMEEAERLCDRLCVLEAG 248
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
497-643 |
1.58e-36 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 135.47 E-value: 1.58e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEaRKMIGICPQSDINFDVLTVEEN 576
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSL-RKEIGYVFQDPQLFPRLTVREN 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 577 LSILASIKGIPANNIIQEVQKVLLDLDMQAIKD----NQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTA 643
Cdd:pfam00005 80 LRLGLLLKGLSKREKDARAEEALEKLGLGDLADrpvgERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
478-689 |
1.68e-36 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 138.40 E-value: 1.68e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEI--DEMFEAR 555
Cdd:cd03261 1 IELRGLTKSFGGRT----VLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLseAELYRLR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 556 KMIGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEvqKVLLDLDMQAIKDNQAKK---LSGGQKRKLSVGIAVLGN 632
Cdd:cd03261 77 RRMGMLFQSGALFDSLTVFENVAFPLREHTRLSEEEIRE--IVLEKLEAVGLRGAEDLYpaeLSGGMKKRVALARALALD 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 633 PKILLLDEPTAGMDPCSRHIVWNL-LKYRKANRVTVFS-THFMDEADILADRKAVISQG 689
Cdd:cd03261 155 PELLLYDEPTAGLDPIASGVIDDLiRSLKKELGLTSIMvTHDLDTAFAIADRIAVLYDG 213
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
1081-1626 |
2.36e-36 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 151.32 E-value: 2.36e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1081 LILMLGSLFAFHHGLYFYPAKFLAVVFcLIAYVPSVILFTYIASFTFKKilntkefwsfiySVTALACVAITETTFFL-- 1158
Cdd:TIGR01257 710 MSIFLLTIFIMHGRILHYSDPFILFLF-LLAFSTATIMQCFLLSTFFSK------------ASLAAACSGVIYFTLYLph 776
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1159 ------QYAVTAVFHYTFCIAIPIYPLLGC--LISF----IKGSWKNMPKNENTYNPWDRLLVAVIMP-----------Y 1215
Cdd:TIGR01257 777 ilcfawQDRMTADLKTAVSLLSPVAFGFGTeyLVRFeeqgLGLQWSNIGNSPLEGDEFSFLLSMKMMLldaalygllawY 856
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1216 LQCIL---------WIFLLQHYEKIHG-GRSIRKDpffRALSQKAKNKKFPEPPINEDEDEDVKAERlkvkELMGCQcce 1285
Cdd:TIGR01257 857 LDQVFpgdygtplpWYFLLQESYWLGGeGCSTREE---RALEKTEPLTEEMEDPEHPEGINDSFFER----ELPGLV--- 926
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1286 ekPAIMVCNLHKEYDdkkdflhsrKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSH 1365
Cdd:TIGR01257 927 --PGVCVKNLVKIFE---------PSGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIE 995
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1366 SSEDDESiKCMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFAL 1445
Cdd:TIGR01257 996 TNLDAVR-QSLGMCPQHNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAI 1074
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1446 SMLGNPQVTLLDEPSTGMDPRAKQHMWRAIrtaFKNKK-RAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKF 1524
Cdd:TIGR01257 1075 AFVGDAKVVVLDEPTSGVDPYSRRSIWDLL---LKYRSgRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPLFLKNCF 1151
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1525 GKGYFLEIKLKdwIENLEIDRLQRE-------------------------------------IQYIFPNASRQESFSSIL 1567
Cdd:TIGR01257 1152 GTGFYLTLVRK--MKNIQSQRGGCEgtcsctskgfstrcparvdeitpeqvldgdvnelmdlVYHHVPEAKLVECIGQEL 1229
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 1568 AFKIPKEDVQ--SLSQSFAKLEEAKRTFAIEEYSFSQATLEQVFVELTkeqeeEDNSCGTL 1626
Cdd:TIGR01257 1230 IFLLPNKNFKqrAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVT-----EDADSGSL 1285
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
477-689 |
3.81e-36 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 141.12 E-value: 3.81e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSeiDEMFEARK 556
Cdd:PRK13536 41 AIDLAGVSKSYGDKA----VVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVP--ARARLARA 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQSDiNFDV-LTVEENLSILASIKGIPANNIiQEVQKVLLDL-DMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPK 634
Cdd:PRK13536 115 RIGVVPQFD-NLDLeFTVRENLLVFGRYFGMSTREI-EAVIPSLLEFaRLESKADARVSDLSGGMKRRLTLARALINDPQ 192
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 635 ILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTV-FSTHFMDEADILADRKAVISQG 689
Cdd:PRK13536 193 LLILDEPTTGLDPHARHLIWERLRSLLARGKTIlLTTHFMEEAERLCDRLCVLEAG 248
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
1312-1512 |
1.28e-35 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 135.04 E-value: 1.28e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1312 TKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI-FLGDYGSHSSEDDESIKCMGYCPQtnpLWPDLT 1390
Cdd:cd03268 12 KKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEItFDGKSYQKNIEALRRIGALIEAPG---FYPNLT 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1391 LQEHFEIYGAVKGMSpgdmKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQH 1470
Cdd:cd03268 89 ARENLRLLARLLGIR----KKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGLDPDGIKE 164
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 146134400 1471 MWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLR 1512
Cdd:cd03268 165 LRELIL-SLRDQGITVLISSHLLSEIQKVADRIGIINKGKLI 205
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
477-689 |
2.76e-35 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 137.63 E-value: 2.76e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEidEMFEARK 556
Cdd:PRK13537 7 PIDFRNVEKRYGDKL----VVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPS--RARHARQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQSDiNFDV-LTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKI 635
Cdd:PRK13537 81 RVGVVPQFD-NLDPdFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDV 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 636 LLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVF-STHFMDEADILADRKAVISQG 689
Cdd:PRK13537 160 LVLDEPTTGLDPQARHLMWERLRSLLARGKTILlTTHFMEEAERLCDRLCVIEEG 214
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
478-689 |
3.92e-35 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 134.59 E-value: 3.92e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEiDEMFE-ARK 556
Cdd:cd03218 1 LRAENLSKRYGKRK----VVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITK-LPMHKrARL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKIL 636
Cdd:cd03218 76 GIGYLPQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 146134400 637 LLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFST-HFMDEADILADRKAVISQG 689
Cdd:cd03218 156 LLDEPFAGVDPIAVQDIQKIIKILKDRGIGVLITdHNVRETLSITDRAYIIYEG 209
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
478-689 |
5.60e-35 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 133.41 E-value: 5.60e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDemfEARKM 557
Cdd:cd03259 1 LELKGLSKTYGSVR----ALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVP---PERRN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:cd03259 74 IGMVFQDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLL 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 146134400 638 LDEPTAGMDPCSR-HIVWNLLKYRKANRVT-VFSTHFMDEADILADRKAVISQG 689
Cdd:cd03259 154 LDEPLSALDAKLReELREELKELQRELGITtIYVTHDQEEALALADRIAVMNEG 207
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
477-689 |
6.80e-35 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 133.95 E-value: 6.80e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEID--EMFEA 554
Cdd:COG1127 5 MIEVRNLTKSFGDRV----VLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSekELYEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 555 RKMIGICPQSDINFDVLTVEENLSI-LASIKGIPANNIIqevQKVLLDLDMQAIKDNQAKK---LSGG-QKRklsVGIA- 628
Cdd:COG1127 81 RRRIGMLFQGGALFDSLTVFENVAFpLREHTDLSEAEIR---ELVLEKLELVGLPGAADKMpseLSGGmRKR---VALAr 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 629 --VLgNPKILLLDEPTAGMDPCSRHIVWNL-LKYRKANRVTVFS-THFMDEADILADRKAVISQG 689
Cdd:COG1127 155 alAL-DPEILLYDEPTAGLDPITSAVIDELiRELRDELGLTSVVvTHDLDSAFAIADRVAVLADG 218
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
477-689 |
7.76e-35 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 136.01 E-value: 7.76e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSeidemFEARK 556
Cdd:COG4152 1 MLELKGLTKRFGDKT----AVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLD-----PEDRR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICP------QSdinfdvLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVL 630
Cdd:COG4152 72 RIGYLPeerglyPK------MKVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALL 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 631 GNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTV-FSTHFMDEADILADRKAVISQG 689
Cdd:COG4152 146 HDPELLILDEPFSGLDPVNVELLKDVIRELAAKGTTViFSSHQMELVEELCDRIVIINKG 205
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
478-689 |
1.70e-34 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 132.02 E-value: 1.70e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSeidemFEARKM 557
Cdd:cd03269 1 LEVENVTKRFGRVT----ALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLD-----IAARNR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:cd03269 72 IGYLPEERGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLI 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 146134400 638 LDEPTAGMDPCSRHIVWN-LLKYRKANRVTVFSTHFMDEADILADRKAVISQG 689
Cdd:cd03269 152 LDEPFSGLDPVNVELLKDvIRELARAGKTVILSTHQMELVEELCDRVLLLNKG 204
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
478-696 |
1.98e-34 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 132.81 E-value: 1.98e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTEnveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMfEARKM 557
Cdd:cd03295 1 IEFENVTKRYGGGKK---AVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPV-ELRRK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKV--LLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKI 635
Cdd:cd03295 77 IGYVIQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELlaLVGLDPAEFADRYPHELSGGQQQRVGVARALAADPPL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 636 LLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGS 696
Cdd:cd03295 157 LLMDEPFGALDPITRDQLQEEFKrlQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGT 219
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
475-691 |
6.74e-34 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 131.30 E-value: 6.74e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 475 KEAIRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFea 554
Cdd:cd03267 15 KEPGLIGSLKSLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVPWKRRKKF-- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 555 RKMIGIC--PQSDINFDvLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGN 632
Cdd:cd03267 93 LRRIGVVfgQKTQLWWD-LPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHE 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 633 PKILLLDEPTAGMDPCSRHIVWNLLK-YRKANRVTV-FSTHFMDEADILADRKAVISQGML 691
Cdd:cd03267 172 PEILFLDEPTIGLDVVAQENIRNFLKeYNRERGTTVlLTSHYMKDIEALARRVLVIDKGRL 232
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
1288-1491 |
7.94e-34 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 129.91 E-value: 7.94e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1288 PAIMVCNLHKEYDDKKDFLHsrkttkvatkyISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSS 1367
Cdd:COG4133 1 MMLEAENLSCRRGERLLFSG-----------LSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDA 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1368 EDDESiKCMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDmkEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSM 1447
Cdd:COG4133 70 REDYR-RRLAYLGHADGLKPELTVRENLRFWAALYGLRADR--EAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLL 146
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 146134400 1448 LGNPQVTLLDEPSTGMDPRAKQHMWRAIRtAFKNKKRAALLTTH 1491
Cdd:COG4133 147 LSPAPLWLLDEPFTALDAAGVALLAELIA-AHLARGGAVLLTTH 189
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
477-696 |
8.75e-34 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 132.04 E-value: 8.75e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTENveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEiDEMFEARK 556
Cdd:PRK13632 7 MIKVENVSFSYPNSENN--ALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISK-ENLKEIRK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQS-DINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKlsVGIA-VLG-NP 633
Cdd:PRK13632 84 KIGIIFQNpDNQFIGATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQR--VAIAsVLAlNP 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 634 KILLLDEPTAGMDPCSRH-IVWNLLKYRKANRVTVFS-THFMDEAdILADRKAVISQGMLKCVGS 696
Cdd:PRK13632 162 EIIIFDESTSMLDPKGKReIKKIMVDLRKTRKKTLISiTHDMDEA-ILADKVIVFSEGKLIAQGK 225
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
478-691 |
9.33e-34 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 129.94 E-value: 9.33e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTEnveaLRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfaSIY--GHRVSEIDeMFEAR 555
Cdd:COG4619 1 LELEGLSFRVGGKPI----LSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSG--EIYldGKPLSAMP-PPEWR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 556 KMIGICPQ-SDINFDvlTVEENLSILASIKGIPANniIQEVQKVL--LDLDmQAIKDNQAKKLSGGQKRKLSVGIAVLGN 632
Cdd:COG4619 74 RQVAYVPQePALWGG--TVRDNLPFPFQLRERKFD--RERALELLerLGLP-PDILDKPVERLSGGERQRLALIRALLLQ 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 633 PKILLLDEPTAGMDPCSRHIVWNLLK-YRKANRVTVFS-THFMDEADILADRKAVISQGML 691
Cdd:COG4619 149 PDVLLLDEPTSALDPENTRRVEELLReYLAEEGRAVLWvSHDPEQIERVADRVLTLEAGRL 209
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
478-689 |
1.26e-33 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 127.88 E-value: 1.26e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYrkKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDeMFEARKM 557
Cdd:cd03228 1 IEFKNVSFSY--PGRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLD-LESLRKN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDvLTVEENLsilasikgipanniiqevqkvlldldmqaikdnqakkLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:cd03228 78 IAYVPQDPFLFS-GTIRENI-------------------------------------LSGGQRQRIAIARALLRDPPILI 119
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADiLADRKAVISQG 689
Cdd:cd03228 120 LDEATSALDPETEALILEALRALAKGKTVIVIAHRLSTIR-DADRIIVLDDG 170
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
478-689 |
9.33e-33 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 127.70 E-value: 9.33e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEID--EMFEAR 555
Cdd:cd03258 2 IELKNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSgkELRKAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 556 KMIGICPQsdiNFDVL---TVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKlsVGIA--VL 630
Cdd:cd03258 82 RRIGMIFQ---HFNLLssrTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQR--VGIAraLA 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 631 GNPKILLLDEPTAGMDPCSRHIVWNLLkyRKANR---VT-VFSTHFMDEADILADRKAVISQG 689
Cdd:cd03258 157 NNPKVLLCDEATSALDPETTQSILALL--RDINRelgLTiVLITHEMEVVKRICDRVAVMEKG 217
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
1294-1515 |
1.57e-32 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 126.48 E-value: 1.57e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYDDKkdflhsrkttkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshsseDDESI 1373
Cdd:cd03259 5 GLSKTYGSV-----------RALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILI---------DGRDV 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1374 KCM-------GYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALS 1446
Cdd:cd03259 65 TGVpperrniGMVFQDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARA 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 1447 MLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIG 1515
Cdd:cd03259 145 LAREPSLLLLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
1319-1510 |
2.09e-32 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 126.04 E-value: 2.09e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQtNPlwpD-----LTLQE 1393
Cdd:cd03225 20 ISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRRKVGLVFQ-NP---DdqffgPTVEE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1394 hfEI-YGAVK-GMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHM 1471
Cdd:cd03225 96 --EVaFGLENlGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEPTAGLDPAGRREL 173
|
170 180 190
....*....|....*....|....*....|....*....
gi 146134400 1472 WRAIRTaFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQ 1510
Cdd:cd03225 174 LELLKK-LKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
1292-1510 |
6.36e-32 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 122.74 E-value: 6.36e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1292 VCNLHKEYDDKKDFLHsrkttkvatkyISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDE 1371
Cdd:cd00267 2 IENLSFRYGGRTALDN-----------VSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEE 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1372 SIKCMGYCPQtnplwpdltlqehfeiygavkgmspgdmkevisritkaldlkehlqktvkkLPAGIKRKLCFALSMLGNP 1451
Cdd:cd00267 71 LRRRIGYVPQ---------------------------------------------------LSGGQRQRVALARALLLNP 99
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 1452 QVTLLDEPSTGMDPRAKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQ 1510
Cdd:cd00267 100 DLLLLDEPTSGLDPASRERLLELLR-ELAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
1290-1518 |
9.31e-32 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 124.75 E-value: 9.31e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKKDFLHSrkttkvatkyISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDygshssED 1369
Cdd:COG1122 1 IELENLSFSYPGGTPALDD----------VSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDG------KD 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 --DESIKCM----GYCPQtNPlwpDL-----TLQEhfEI-YGAV-KGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAG 1436
Cdd:COG1122 65 itKKNLRELrrkvGLVFQ-NP---DDqlfapTVEE--DVaFGPEnLGLPREEIRERVEEALELVGLEHLADRPPHELSGG 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1437 IKRKLCFA--LSMlgNPQVTLLDEPSTGMDPRAKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCI 1514
Cdd:COG1122 139 QKQRVAIAgvLAM--EPEVLVLDEPTAGLDPRGRRELLELLK-RLNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVAD 215
|
....
gi 146134400 1515 GTVQ 1518
Cdd:COG1122 216 GTPR 219
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
477-691 |
1.74e-31 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 124.43 E-value: 1.74e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEidemfeARK 556
Cdd:COG1121 6 AIELENLTVSYGGRP----VLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRR------ARR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQ-SDINFDV-LTVEE----NLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVL 630
Cdd:COG1121 76 RIGYVPQrAEVDWDFpITVRDvvlmGRYGRRGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146134400 631 GNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTV-FSTHFMDEADILADRKAVISQGML 691
Cdd:COG1121 156 QDPDLLLLDEPFAGVDAATEEALYELLRELRREGKTIlVVTHDLGAVREYFDRVLLLNRGLV 217
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
479-671 |
2.07e-31 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 122.75 E-value: 2.07e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 479 RISGIQKSYRKKTEnveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEidemFEARKMI 558
Cdd:cd03226 1 RIENISFSYKKGTE---ILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKA----KERRKSI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 559 GICPQ-SDINFDVLTVEENLSIlaSIKGIPANNiiQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:cd03226 74 GYVMQdVDYQLFTDSVREELLL--GLKELDAGN--EQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLI 149
|
170 180 190
....*....|....*....|....*....|....*
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLKYRKANRVTVF-STH 671
Cdd:cd03226 150 FDEPTSGLDYKNMERVGELIRELAAQGKAVIvITH 184
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
478-689 |
2.39e-31 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 123.38 E-value: 2.39e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDE--MFEAR 555
Cdd:cd03257 2 LEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRrlRKIRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 556 KMIGICPQ---SDINFdVLTVE----ENLSILASIKGIPANNIIQEVQKVLLDLDmQAIKDNQAKKLSGGQKRKLSVGIA 628
Cdd:cd03257 82 KEIQMVFQdpmSSLNP-RMTIGeqiaEPLRIHGKLSKKEARKEAVLLLLVGVGLP-EEVLNRYPHELSGGQRQRVAIARA 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 629 VLGNPKILLLDEPTAGMDPCSRHIVWNLLK-YRKANRVTV-FSTHFMDEADILADRKAVISQG 689
Cdd:cd03257 160 LALNPKLLIADEPTSALDVSVQAQILDLLKkLQEELGLTLlFITHDLGVVAKIADRVAVMYAG 222
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
478-689 |
2.61e-31 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 123.31 E-value: 2.61e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKktenVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVS-----EIdemf 552
Cdd:cd03224 1 LEVENLNAGYGK----SQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITglpphER---- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 553 eARKMIGICPQSDINFDVLTVEENLsILASIKGIPANN--IIQEVqkvlLDL--DMQAIKDNQAKKLSGGQKRKLSVGIA 628
Cdd:cd03224 73 -ARAGIGYVPEGRRIFPELTVEENL-LLGAYARRRAKRkaRLERV----YELfpRLKERRKQLAGTLSGGEQQMLAIARA 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146134400 629 VLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVF-STHFMDEADILADRKAVISQG 689
Cdd:cd03224 147 LMSRPKLLLLDEPSEGLAPKIVEEIFEAIRELRDEGVTILlVEQNARFALEIADRAYVLERG 208
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
478-691 |
7.55e-31 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 121.90 E-value: 7.55e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKtenvEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCP-----PSDGFASIYGHRVSEIDEMF 552
Cdd:cd03260 1 IELRDLNVYYGDK----HALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDlipgaPDEGEVLLDGKDIYDLDVDV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 553 EA-RKMIGICPQSDINFDvLTVEENLSILASIKGIPANNIIQE-VQKVLLDLDM-QAIKDNQ-AKKLSGGQKRKLSVGIA 628
Cdd:cd03260 77 LElRRRVGMVFQKPNPFP-GSIYDNVAYGLRLHGIKLKEELDErVEEALRKAALwDEVKDRLhALGLSGGQQQRLCLARA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 629 VLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGML 691
Cdd:cd03260 156 LANEPEVLLLDEPTSALDPISTAKIEELIAELKKEYTIVIVTHNMQQAARVADRTAFLLNGRL 218
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
477-696 |
1.69e-30 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 121.69 E-value: 1.69e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMfEARK 556
Cdd:COG1120 1 MLEAENLSVGYGGRP----VLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRR-ELAR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQS-DINFDvLTVEE--------NLSILASikgiPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKlsVGI 627
Cdd:COG1120 76 RIAYVPQEpPAPFG-LTVRElvalgrypHLGLFGR----PSAEDREAVEEALERTGLEHLADRPVDELSGGERQR--VLI 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 628 A-VL-GNPKILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGS 696
Cdd:COG1120 149 ArALaQEPPLLLLDEPTSHLDLAHQLEVLELLRrlARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGP 221
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
477-689 |
1.70e-30 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 121.70 E-value: 1.70e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTEnveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEID--EMFEA 554
Cdd:COG3638 2 MLELRNLSKRYPGGTP---ALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRgrALRRL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 555 RKMIGICPQsdiNFDV---LTVEEN--------LSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKl 623
Cdd:COG3638 79 RRRIGMIFQ---QFNLvprLSVLTNvlagrlgrTSTWRSLLGLFPPEDRERALEALERVGLADKAYQRADQLSGGQQQR- 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146134400 624 sVGIA--VLGNPKILLLDEPTAGMDPCSRHIVWNLLkyRKANR---VTV-FSTHFMDEADILADRKAVISQG 689
Cdd:COG3638 155 -VAIAraLVQEPKLILADEPVASLDPKTARQVMDLL--RRIARedgITVvVNLHQVDLARRYADRIIGLRDG 223
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
478-704 |
1.87e-30 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 122.56 E-value: 1.87e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTEN-VEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRV--SEIDEMFEA 554
Cdd:TIGR04521 1 IKLKNVSYIYQPGTPFeKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDItaKKKKKLKDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 555 RKMIGIC---PQSDInFDvLTVEE-------NLsilasikGIPANNIIQEVQKVL--LDLDmQAIKDNQAKKLSGGQKRK 622
Cdd:TIGR04521 81 RKKVGLVfqfPEHQL-FE-ETVYKdiafgpkNL-------GLSEEEAEERVKEALelVGLD-EEYLERSPFELSGGQMRR 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 623 lsVGIA-VLG-NPKILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSS- 697
Cdd:TIGR04521 151 --VAIAgVLAmEPEVLILDEPTAGLDPKGRKEILDLFKrlHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPr 228
|
....*...
gi 146134400 698 -IFLKSKW 704
Cdd:TIGR04521 229 eVFSDVDE 236
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
474-689 |
2.36e-30 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 127.71 E-value: 2.36e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 474 GKEAIRISGIQKSYR-KKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfaSIY--GHRVSEID- 549
Cdd:COG1123 257 AEPLLEVRNLSKRYPvRGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSG--SILfdGKDLTKLSr 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 550 -EMFEARKMIGICPQ---SDINfDVLTVEENLS-ILASIKGIPANNIIQEVQKVL----LDLDMqaikdnqAKK----LS 616
Cdd:COG1123 335 rSLRELRRRVQMVFQdpySSLN-PRMTVGDIIAePLRLHGLLSRAERRERVAELLervgLPPDL-------ADRypheLS 406
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 617 GGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLK-YRKANRVT-VFSTHFMDEADILADRKAVISQG 689
Cdd:COG1123 407 GGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRdLQRELGLTyLFISHDLAVVRYIADRVAVMYDG 481
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
478-656 |
3.05e-30 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 120.52 E-value: 3.05e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDeMFE-ARK 556
Cdd:COG1137 4 LEAENLVKSYGKRT----VVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLP-MHKrARL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQ-SDInFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKI 635
Cdd:COG1137 79 GIGYLPQeASI-FRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKF 157
|
170 180
....*....|....*....|....*
gi 146134400 636 LLLDEPTAGMDPCS----RHIVWNL 656
Cdd:COG1137 158 ILLDEPFAGVDPIAvadiQKIIRHL 182
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
478-691 |
5.29e-30 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 119.39 E-value: 5.29e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKkteNVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEI--DEMFEAR 555
Cdd:COG2884 2 IRFENVSKRYPG---GREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLkrREIPYLR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 556 KMIGICPQsDIN--FDvLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGG-QKRklsVGI--AVL 630
Cdd:COG2884 79 RRIGVVFQ-DFRllPD-RTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGeQQR---VAIarALV 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 631 GNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVF-STHfmdEADILADRKA---VISQGML 691
Cdd:COG2884 154 NRPELLLADEPTGNLDPETSWEIMELLEEINRRGTTVLiATH---DLELVDRMPKrvlELEDGRL 215
|
|
| LPS_export_lptB |
TIGR04406 |
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ... |
1292-1520 |
1.07e-29 |
|
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 275199 [Multi-domain] Cd Length: 239 Bit Score: 118.92 E-value: 1.07e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1292 VCNLHKEYDDKKdflhsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYG-SHSSEDD 1370
Cdd:TIGR04406 4 AENLIKSYKKRK-----------VVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDiTHLPMHE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1371 ESIKCMGYCPQTNPLWPDLTLQEHFEiygAVKGMSPGDMKEVISRITKALdLKEHLQKTVKKLPA-----GIKRKLCFAL 1445
Cdd:TIGR04406 73 RARLGIGYLPQEASIFRKLTVEENIM---AVLEIRKDLDRAEREERLEAL-LEEFQISHLRDNKAmslsgGERRRVEIAR 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 1446 SMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTaFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL 1520
Cdd:TIGR04406 149 ALATNPKFILLDEPFAGVDPIAVGDIKKIIKH-LKERGIGVLITDHNVRETLDICDRAYIISDGKVLAEGTPAEI 222
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
477-696 |
1.11e-29 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 122.10 E-value: 1.11e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfaSIY--GHRVSEIDEmfeA 554
Cdd:COG3839 3 SLELENVSKSY----GGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSG--EILigGRDVTDLPP---K 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 555 RKMIGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPK 634
Cdd:COG3839 74 DRNIAMVFQSYALYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPK 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 635 ILLLDEPTAGMDPCSRhivWNL---LKY--RKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGS 696
Cdd:COG3839 154 VFLLDEPLSNLDAKLR---VEMraeIKRlhRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGT 217
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
477-689 |
1.16e-29 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 125.40 E-value: 1.16e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTenVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPS---DGFASIYGHRVSEIDEmFE 553
Cdd:COG1123 4 LLEVRDLSVRYPGGD--VPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELSE-AL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 554 ARKMIGICPQS-DINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGN 632
Cdd:COG1123 81 RGRRIGMVFQDpMTQLNPVTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALD 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 633 PKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVT--VFSTHFMDEADILADRKAVISQG 689
Cdd:COG1123 161 PDLLIADEPTTALDVTTQAEILDLLRELQRERGTtvLLITHDLGVVAEIADRVVVMDDG 219
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
477-691 |
1.28e-29 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 119.14 E-value: 1.28e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARK 556
Cdd:COG1124 1 MLEVRNLSVSYGQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKAFRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 --MIGICPQSDINfDVLTVEENLSILASIKGIPanNIIQEVQKVLLDLDM-QAIKDNQAKKLSGGQKRKLSVGIAVLGNP 633
Cdd:COG1124 81 vqMVFQDPYASLH-PRHTVDRILAEPLRIHGLP--DREERIAELLEQVGLpPSFLDRYPHQLSGGQRQRVAIARALILEP 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 634 KILLLDEPTAGMDPCSRHIVWNLLK-YRKANRVT-VFSTHFMDEADILADRKAVISQGML 691
Cdd:COG1124 158 ELLLLDEPTSALDVSVQAEILNLLKdLREERGLTyLFVSHDLAVVAHLCDRVAVMQNGRI 217
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
1314-1519 |
1.43e-29 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 118.69 E-value: 1.43e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1314 VATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI-FLGDYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQ 1392
Cdd:cd03219 14 VALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVlFDGEDITGLPPHEIARLGIGRTFQIPRLFPELTVL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1393 E-------HFEIYGAVKGMSPGDMKEVISRITKALD---LKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTG 1462
Cdd:cd03219 94 EnvmvaaqARTGSGLLLARARREEREARERAEELLErvgLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDEPAAG 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 1463 MDPRAKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQH 1519
Cdd:cd03219 174 LNPEETEELAELIR-ELRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDE 229
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
475-699 |
1.50e-29 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 119.73 E-value: 1.50e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 475 KEAIRISGIqkSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEiDEMFEA 554
Cdd:PRK13635 3 EEIIRVEHI--SFRYPDAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSE-ETVWDV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 555 RKMIGICPQS-DINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSV-GIAVLgN 632
Cdd:PRK13635 80 RRQVGMVFQNpDNQFVGATVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIaGVLAL-Q 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 633 PKILLLDEPTAGMDPCSRHIVWNLLKYRKAN-RVTVFS-THFMDEAdILADRKAVISQGMLKCVG--SSIF 699
Cdd:PRK13635 159 PDIIILDEATSMLDPRGRREVLETVRQLKEQkGITVLSiTHDLDEA-AQADRVIVMNKGEILEEGtpEEIF 228
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
478-689 |
1.83e-29 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 116.13 E-value: 1.83e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRV-SEIDEMFEARK 556
Cdd:cd03229 1 LELKNVSKRYGQKT----VLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLtDLEDELPPLRR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQSDINFDVLTVEENLSILasikgipanniiqevqkvlldldmqaikdnqakkLSGGQKRKLSVGIAVLGNPKIL 636
Cdd:cd03229 77 RIGMVFQDFALFPHLTVLENIALG----------------------------------LSGGQQQRVALARALAMDPDVL 122
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 637 LLDEPTAGMDPCSRHIVWNLLKYRKANR-VTV-FSTHFMDEADILADRKAVISQG 689
Cdd:cd03229 123 LLDEPTSALDPITRREVRALLKSLQAQLgITVvLVTHDLDEAARLADRVVVLRDG 177
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
497-671 |
2.27e-29 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 116.50 E-value: 2.27e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCG-LCPPSD-GFASIYGHRVSeideMFEARKMIGICPQSDINFDVLTVE 574
Cdd:cd03213 25 LKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrRTGLGVsGEVLINGRPLD----KRSFRKIIGYVPQDDILHPTLTVR 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 575 ENLSILASIKGIpanniiqevqkvlldldmqaikdnqakklSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVW 654
Cdd:cd03213 101 ETLMFAAKLRGL-----------------------------SGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVM 151
|
170
....*....|....*...
gi 146134400 655 NLLK-YRKANRVTVFSTH 671
Cdd:cd03213 152 SLLRrLADTGRTIICSIH 169
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
1319-1461 |
4.14e-29 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 114.28 E-value: 4.14e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQEHFEIY 1398
Cdd:pfam00005 4 VSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDPQLFPRLTVRENLRLG 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 1399 GAVKGMSPGDMKEVISRITKALDL----KEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPST 1461
Cdd:pfam00005 84 LLLKGLSKREKDARAEEALEKLGLgdlaDRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
1292-1516 |
5.28e-29 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 116.87 E-value: 5.28e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1292 VCNLHKEYddkkdflhsrKTTKVaTKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYG-SHSSEDD 1370
Cdd:cd03218 3 AENLSKRY----------GKRKV-VNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDiTKLPMHK 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1371 ESIKCMGYCPQTNPLWPDLTLQEHfeIYGAVKGMspGDMKEVISRITKALdLKE-HLQKTVKK----LPAGIKRKLCFAL 1445
Cdd:cd03218 72 RARLGIGYLPQEASIFRKLTVEEN--ILAVLEIR--GLSKKEREEKLEEL-LEEfHITHLRKSkassLSGGERRRVEIAR 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 1446 SMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTaFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGT 1516
Cdd:cd03218 147 ALATNPKFLLLDEPFAGVDPIAVQDIQKIIKI-LKDRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGT 216
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
478-689 |
7.15e-29 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 119.41 E-value: 7.15e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfaSIY--GHRVSEID--EMFE 553
Cdd:COG1135 2 IELENLSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSG--SVLvdGVDLTALSerELRA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 554 ARKMIGICPQsdiNFDVL---TVEENLSILASIKGIPANNIIQEVQKvLLDL-DMQAIKDNQAKKLSGGQKRKlsVGIA- 628
Cdd:COG1135 80 ARRKIGMIFQ---HFNLLssrTVAENVALPLEIAGVPKAEIRKRVAE-LLELvGLSDKADAYPSQLSGGQKQR--VGIAr 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 629 VL-GNPKILLLDEPTAGMDPCSRHIVWNLLKyrKANR---VT-VFSTHFMDEADILADRKAVISQG 689
Cdd:COG1135 154 ALaNNPKVLLCDEATSALDPETTRSILDLLK--DINRelgLTiVLITHEMDVVRRICDRVAVLENG 217
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
478-695 |
8.50e-29 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 115.81 E-value: 8.50e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDemfEARKM 557
Cdd:cd03301 1 VELENVTKRF----GNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLP---PKDRD 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:cd03301 74 IAMVFQNYALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVG 695
Cdd:cd03301 154 MDEPLSNLDAKLRVQMRAELKrlQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
477-710 |
2.09e-28 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 123.79 E-value: 2.09e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTENVeaLRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfaSIY--GHRVSEIDeMFEA 554
Cdd:COG2274 473 DIELENVSFRYPGDSPPV--LDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSG--RILidGIDLRQID-PASL 547
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 555 RKMIGICPQSDinfdVL---TVEENLSILASikGIPANNIIQEVQKVLLD---------LDMQaIKDNqAKKLSGGQKRK 622
Cdd:COG2274 548 RRQIGVVLQDV----FLfsgTIRENITLGDP--DATDEEIIEAARLAGLHdfiealpmgYDTV-VGEG-GSNLSGGQRQR 619
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 623 LSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHfmDEADI-LADRKAVISQGMLKCVGSSIFLK 701
Cdd:COG2274 620 LAIARALLRNPRILILDEATSALDAETEAIILENLRRLLKGRTVIIIAH--RLSTIrLADRIIVLDKGRIVEDGTHEELL 697
|
....*....
gi 146134400 702 SKWGIGYRL 710
Cdd:COG2274 698 ARKGLYAEL 706
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
493-691 |
3.73e-28 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 113.78 E-value: 3.73e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 493 NVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIdemfeaRKMIGICPQS-DINFDV- 570
Cdd:cd03235 11 GHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKE------RKRIGYVPQRrSIDRDFp 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 571 LTVEE--NLSILASIKGIPANNII--QEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMD 646
Cdd:cd03235 85 ISVRDvvLMGLYGHKGLFRRLSKAdkAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGVD 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 146134400 647 PCSRHIVWNLLK-YRKANRVTVFSTHFMDEADILADRKAVISQGML 691
Cdd:cd03235 165 PKTQEDIYELLReLRREGMTILVVTHDLGLVLEYFDRVLLLNRTVV 210
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
478-689 |
3.90e-28 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 114.46 E-value: 3.90e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKktenVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDG---F--ASIYGHRVSEIdemf 552
Cdd:cd03219 1 LEVRGLTKRFGG----LVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGsvlFdgEDITGLPPHEI---- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 553 eARKmiGIC-----PQSdinFDVLTVEENLSI-------LASIKGIPANNIIQEVQKV--LLD-LDMQAIKDNQAKKLSG 617
Cdd:cd03219 73 -ARL--GIGrtfqiPRL---FPELTVLENVMVaaqartgSGLLLARARREEREARERAeeLLErVGLADLADRPAGELSY 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 618 GQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTV-FSTHFMDEADILADRKAVISQG 689
Cdd:cd03219 147 GQQRRLEIARALATDPKLLLLDEPAAGLNPEETEELAELIRELRERGITVlLVEHDMDVVMSLADRVTVLDQG 219
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
477-689 |
4.55e-28 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 117.51 E-value: 4.55e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIdemfEARK 556
Cdd:COG3842 5 ALELENVSKRY----GDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGL----PPEK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 -MIGICPQSDINFDVLTVEEN----LsilaSIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQK-RklsVGIA-- 628
Cdd:COG3842 77 rNVGMVFQDYALFPHLTVAENvafgL----RMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQqR---VALAra 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 146134400 629 -VLgNPKILLLDEPTAGMDPCSRHIVWNLLK-YRKANRVT-VFSTHFMDEADILADRKAVISQG 689
Cdd:COG3842 150 lAP-EPRVLLLDEPLSALDAKLREEMREELRrLQRELGITfIYVTHDQEEALALADRIAVMNDG 212
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
1314-1511 |
4.56e-28 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 114.75 E-value: 4.56e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1314 VATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshsseDDESIKCMGycP------------Q 1381
Cdd:COG0411 18 VAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILF---------DGRDITGLP--PhriarlgiartfQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1382 TNPLWPDLTLQEHFEI-------YGAVKGM-----SPGDMKEVISRITKALD---LKEHLQKTVKKLPAGIKRKLCFALS 1446
Cdd:COG0411 87 NPRLFPELTVLENVLVaaharlgRGLLAALlrlprARREEREARERAEELLErvgLADRADEPAGNLSYGQQRRLEIARA 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 1447 MLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:COG0411 167 LATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRV 231
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
496-676 |
5.08e-28 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 123.31 E-value: 5.08e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 496 ALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDemFEARKMIGICPQSdinFDV---LT 572
Cdd:NF033858 281 AVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAGD--IATRRRVGYMSQA---FSLygeLT 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 573 VEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHI 652
Cdd:NF033858 356 VRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDM 435
|
170 180
....*....|....*....|....*.
gi 146134400 653 VWNLL-KYRKANRVTVF-STHFMDEA 676
Cdd:NF033858 436 FWRLLiELSREDGVTIFiSTHFMNEA 461
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
478-689 |
1.07e-27 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 116.05 E-value: 1.07e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEID--EMFEAR 555
Cdd:PRK11153 2 IELKNISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSekELRKAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 556 KMIGICPQsdiNFDVL---TVEENLSILASIKGIPANNIIQEVQKvLLDL-DMQAIKDNQAKKLSGGQKRKlsVGIA-VL 630
Cdd:PRK11153 82 RQIGMIFQ---HFNLLssrTVFDNVALPLELAGTPKAEIKARVTE-LLELvGLSDKADRYPAQLSGGQKQR--VAIArAL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 146134400 631 GN-PKILLLDEPTAGMDPCSRHIVWNLLKyrKANR---VT-VFSTHFMDEADILADRKAVISQG 689
Cdd:PRK11153 156 ASnPKVLLCDEATSALDPATTRSILELLK--DINRelgLTiVLITHEMDVVKRICDRVAVIDAG 217
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
486-701 |
1.23e-27 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 114.51 E-value: 1.23e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 486 SYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFAS---IYGHRVSEiDEMFEARKMIGICP 562
Cdd:PRK13640 12 SFTYPDSKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPNSkitVDGITLTA-KTVWDIREKVGIVF 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 563 QS-DINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSV-GIAVLGnPKILLLDE 640
Cdd:PRK13640 91 QNpDNQFVGATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIaGILAVE-PKIIILDE 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 641 PTAGMDPCSRHIVWNLL-KYRKANRVTVFS-THFMDEADiLADRKAVISQGMLKCVGS--SIFLK 701
Cdd:PRK13640 170 STSMLDPAGKEQILKLIrKLKKKNNLTVISiTHDIDEAN-MADQVLVLDDGKLLAQGSpvEIFSK 233
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
477-710 |
2.24e-27 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 119.10 E-value: 2.24e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTENVeaLRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMfEARK 556
Cdd:COG4987 333 SLELEDVSFRYPGAGRPV--LDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDED-DLRR 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQ-SDInFDVlTVEENLSIlasikgipANN------IIQEVQKVLLD---------LDMQAikDNQAKKLSGGQK 620
Cdd:COG4987 410 RIAVVPQrPHL-FDT-TLRENLRL--------ARPdatdeeLWAALERVGLGdwlaalpdgLDTWL--GEGGRRLSGGER 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 621 RKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADiLADRKAVISQGMLKCVGSSIFL 700
Cdd:COG4987 478 RRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEALAGRTVLLITHRLAGLE-RMDRILVLEDGRIVEQGTHEEL 556
|
250
....*....|
gi 146134400 701 KSKWGIGYRL 710
Cdd:COG4987 557 LAQNGRYRQL 566
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
478-689 |
2.45e-27 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 112.28 E-value: 2.45e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVS--EIDEMFEAR 555
Cdd:cd03256 1 IEVENLSKTYP---NGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINklKGKALRQLR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 556 KMIGICPQSDINFDVLTVEEN-----LSILASIKGIPANNIIQEVQKVLLDLDMQAIKD---NQAKKLSGGQKRKlsVGI 627
Cdd:cd03256 78 RQIGMIFQQFNLIERLSVLENvlsgrLGRRSTWRSLFGLFPKEEKQRALAALERVGLLDkayQRADQLSGGQQQR--VAI 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 628 A--VLGNPKILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADILADRKAVISQG 689
Cdd:cd03256 156 AraLMQQPKLILADEPVASLDPASSRQVMDLLKriNREEGITVIVSLHQVDLAREYADRIVGLKDG 221
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
1290-1510 |
3.63e-27 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 109.58 E-value: 3.63e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKKdflhsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG--DYGSHSS 1367
Cdd:cd03229 1 LELKNVSKRYGQKT-----------VLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDgeDLTDLED 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1368 EDDESIKCMGYCPQTNPLWPDLTlqehfeiygavkgmspgdmkeVISRITKALDlkehlqktvkklpAGIKRKLCFALSM 1447
Cdd:cd03229 70 ELPPLRRRIGMVFQDFALFPHLT---------------------VLENIALGLS-------------GGQQQRVALARAL 115
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1448 LGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQ 1510
Cdd:cd03229 116 AMDPDVLLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
1319-1522 |
3.63e-27 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 111.37 E-value: 3.63e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDygshssEDDESIKC-------MGYCPQTNPLWPDLTL 1391
Cdd:cd03224 19 VSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDG------RDITGLPPheraragIGYVPEGRRIFPELTV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1392 QEHFEIYGAVKGMSPG--DMKEVISRITKaldLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQ 1469
Cdd:cd03224 93 EENLLLGAYARRRAKRkaRLERVYELFPR---LKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAPKIVE 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1470 HMWRAIRTaFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKS 1522
Cdd:cd03224 170 EIFEAIRE-LRDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAELLA 221
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
478-696 |
3.91e-27 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 109.06 E-value: 3.91e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSeIDEMFEARKM 557
Cdd:cd03216 1 LELRGITKRF----GGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVS-FASPRDARRA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 -IGICPQsdinfdvltveenlsilasikgipanniiqevqkvlldldmqaikdnqakkLSGGQKRKLSVGIAVLGNPKIL 636
Cdd:cd03216 76 gIAMVYQ---------------------------------------------------LSVGERQMVEIARALARNARLL 104
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 637 LLDEPTAGMDPCSRHIVWNLLKYRKANRVTV-FSTHFMDEADILADRKAVISQGmlKCVGS 696
Cdd:cd03216 105 ILDEPTAALTPAEVERLFKVIRRLRAQGVAViFISHRLDEVFEIADRVTVLRDG--RVVGT 163
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
477-696 |
5.09e-27 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 111.28 E-value: 5.09e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMfeaRK 556
Cdd:cd03296 2 SIEVRNVSKRF----GDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQ---ER 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQSDINFDVLTVEENLSILASIKGI----PANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGN 632
Cdd:cd03296 75 NVGFVFQHYALFRHMTVFDNVAFGLRVKPRserpPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVE 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 633 PKILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGS 696
Cdd:cd03296 155 PKVLLLDEPFGALDAKVRKELRRWLRrlHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGT 220
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
1319-1518 |
5.74e-27 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 111.67 E-value: 5.74e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshsseDDESI---------KCMGYCPQTNPLWPDL 1389
Cdd:COG1120 20 VSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLL---------DGRDLaslsrrelaRRIAYVPQEPPAPFGL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1390 TLQE--------HFeiyGAVKGMSPGDmKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPST 1461
Cdd:COG1120 91 TVRElvalgrypHL---GLFGRPSAED-REAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLLLDEPTS 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 1462 GMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQ 1518
Cdd:COG1120 167 HLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPE 223
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
478-696 |
1.10e-26 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 110.02 E-value: 1.10e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEmfeARKM 557
Cdd:cd03300 1 IELENVSKFYGGFV----ALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPP---HKRP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:cd03300 74 VNTVFQNYALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLL 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 638 LDEPTAGMDpcsrhivwnlLKYRKANRVT------------VFSTHFMDEADILADRKAVISQGMLKCVGS 696
Cdd:cd03300 154 LDEPLGALD----------LKLRKDMQLElkrlqkelgitfVFVTHDQEEALTMSDRIAVMNKGKIQQIGT 214
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
479-695 |
1.10e-26 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 108.29 E-value: 1.10e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 479 RISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMfEARKMI 558
Cdd:cd03214 1 EVENLSVGYGGRT----VLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPK-ELARKI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 559 GICPQsdinfdvltveenlsilasikgipanniiqevqkVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLL 638
Cdd:cd03214 76 AYVPQ----------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLL 121
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 639 DEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVG 695
Cdd:cd03214 122 DEPTSHLDIAHQIELLELLRrlARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
495-689 |
1.27e-26 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 109.92 E-value: 1.27e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 495 EALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQSDINFDVLTVE 574
Cdd:TIGR03410 14 HILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERARAGIAYVPQGREIFPRLTVE 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 575 ENLSILASIKGIPANNIIQEVqkvlLDLdMQAIKDNQAKK---LSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPcsrH 651
Cdd:TIGR03410 94 ENLLTGLAALPRRSRKIPDEI----YEL-FPVLKEMLGRRggdLSGGQQQQLAIARALVTRPKLLLLDEPTEGIQP---S 165
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 146134400 652 IVWN----LLKYRKANRVTV-FSTHFMDEADILADRKAVISQG 689
Cdd:TIGR03410 166 IIKDigrvIRRLRAEGGMAIlLVEQYLDFARELADRYYVMERG 208
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
478-676 |
1.33e-26 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 110.95 E-value: 1.33e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTEN-VEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARK 556
Cdd:COG1101 2 LELKNLSKTFNPGTVNeKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRAKY 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 --------MIGICPQsdinfdvLTVEENLSiLASIKG-----IPANNI--IQEVQKVL--LDLDMQAIKDNQAKKLSGGQ 619
Cdd:COG1101 82 igrvfqdpMMGTAPS-------MTIEENLA-LAYRRGkrrglRRGLTKkrRELFRELLatLGLGLENRLDTKVGLLSGGQ 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 620 KRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYR-KANRVTVFS-THFMDEA 676
Cdd:COG1101 154 RQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIvEENNLTTLMvTHNMEQA 212
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
478-694 |
1.38e-26 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 111.68 E-value: 1.38e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTE-NVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfaSIYGHRVSEIDE---MFE 553
Cdd:PRK13637 3 IKIENLTHIYMEGTPfEKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSG--KIIIDGVDITDKkvkLSD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 554 ARKMIGIC---PQSDInFDVlTVEENLSILASIKGIPANNIIQEVQKV--LLDLDMQAIKDNQAKKLSGGQKRKLSVGIA 628
Cdd:PRK13637 81 IRKKVGLVfqyPEYQL-FEE-TIEKDIAFGPINLGLSEEEIENRVKRAmnIVGLDYEDYKDKSPFELSGGQKRRVAIAGV 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 629 VLGNPKILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADILADRKAVISQGmlKCV 694
Cdd:PRK13637 159 VAMEPKILILDEPTAGLDPKGRDEILNKIKelHKEYNMTIILVSHSMEDVAKLADRIIVMNKG--KCE 224
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
477-696 |
2.52e-26 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 116.01 E-value: 2.52e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYrkkTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMfEARK 556
Cdd:COG4988 336 SIELEDVSFSY---PGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPA-SWRR 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQSDINFDvLTVEENLSILASikGIPANNIIQEVQKVLLD---------LDMQaIKDNqAKKLSGGQKRKLSVGI 627
Cdd:COG4988 412 QIAWVPQNPYLFA-GTIRENLRLGRP--DASDEELEAALEAAGLDefvaalpdgLDTP-LGEG-GRGLSGGQAQRLALAR 486
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 628 AVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHfmDEADI-LADRKAVISQGMLKCVGS 696
Cdd:COG4988 487 ALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKGRTVILITH--RLALLaQADRILVLDDGRIVEQGT 554
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
1319-1506 |
2.74e-26 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 108.39 E-value: 2.74e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdYGSHSSEDDESIkcmGYCPQT---NPLWPdLTLqEHF 1395
Cdd:cd03235 18 VSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRV--FGKPLEKERKRI---GYVPQRrsiDRDFP-ISV-RDV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1396 EIYGAV--KGMSPGDMKEVISRITKALD---LKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQH 1470
Cdd:cd03235 91 VLMGLYghKGLFRRLSKADKAKVDEALErvgLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGVDPKTQED 170
|
170 180 190
....*....|....*....|....*....|....*.
gi 146134400 1471 MWRAIRTAfKNKKRAALLTTHYMEEAEAVCDRVAIM 1506
Cdd:cd03235 171 IYELLREL-RREGMTILVVTHDLGLVLEYFDRVLLL 205
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
478-689 |
2.95e-26 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 110.21 E-value: 2.95e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTENVeALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEiDEMFEARKM 557
Cdd:PRK13650 5 IEVKNLTFKYKEDQEKY-TLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTE-ENVWDIRHK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQS-DINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKIL 636
Cdd:PRK13650 83 IGMVFQNpDNQFVGATVEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKII 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 637 LLDEPTAGMDPCSR-HIVWNLLKYRKANRVTVFS-THFMDEAdILADRKAVISQG 689
Cdd:PRK13650 163 ILDEATSMLDPEGRlELIKTIKGIRDDYQMTVISiTHDLDEV-ALSDRVLVMKNG 216
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1288-1519 |
3.88e-26 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 109.02 E-value: 3.88e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1288 PAIMVCNLHKEYDDKkdflhsrkttkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdYGSHSS 1367
Cdd:COG1121 5 PAIELENLTVSYGGR-----------PVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRL--FGKPPR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1368 EDDESIkcmGYCPQT---NPLWP----DLTLQEHFEIYGAVKGMSPGDmKEVISRITKALDLKEHLQKTVKKLPAGIKRK 1440
Cdd:COG1121 72 RARRRI---GYVPQRaevDWDFPitvrDVVLMGRYGRRGLFRRPSRAD-REAVDEALERVGLEDLADRPIGELSGGQQQR 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 1441 LCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVaIMVSGQLRCIGTVQH 1519
Cdd:COG1121 148 VLLARALAQDPDLLLLDEPFAGVDAATEEALYELLR-ELRREGKTILVVTHDLGAVREYFDRV-LLLNRGLVAHGPPEE 224
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
499-691 |
5.07e-26 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 107.77 E-value: 5.07e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 499 NLSFDIyEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIyGHRVseideMFEARKMIGICP---------QSDINFD 569
Cdd:cd03297 16 KIDFDL-NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVL-NGTV-----LFDSRKKINLPPqqrkiglvfQQYALFP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 570 VLTVEENlsILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCS 649
Cdd:cd03297 89 HLNVREN--LAFGLKRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRAL 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 146134400 650 RHIVWNLLKYRKA--NRVTVFSTHFMDEADILADRKAVISQGML 691
Cdd:cd03297 167 RLQLLPELKQIKKnlNIPVIFVTHDLSEAEYLADRIVVMEDGRL 210
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
493-647 |
5.19e-26 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 108.15 E-value: 5.19e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 493 NVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDG---FA--SIYGHRVSEIdemfeARKMIGICPQS-DI 566
Cdd:COG0410 15 GIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGsirFDgeDITGLPPHRI-----ARLGIGYVPEGrRI 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 567 nFDVLTVEENLsILASIKGIPANNIIQEVQKVLlDL--DMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAG 644
Cdd:COG0410 90 -FPSLTVEENL-LLGAYARRDRAEVRADLERVY-ELfpRLKERRRQRAGTLSGGEQQMLAIGRALMSRPKLLLLDEPSLG 166
|
...
gi 146134400 645 MDP 647
Cdd:COG0410 167 LAP 169
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
488-671 |
5.41e-26 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 108.13 E-value: 5.41e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 488 RKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLcppSDGFASIYGH-----RVSEIDEMfeaRKMIGICP 562
Cdd:cd03234 14 KNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGR---VEGGGTTSGQilfngQPRKPDQF---QKCVAYVR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 563 QSDINFDVLTVEENLSILASIKG--IPANNIIQEV--QKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLL 638
Cdd:cd03234 88 QDDILLPGLTVRETLTYTAILRLprKSSDAIRKKRveDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLIL 167
|
170 180 190
....*....|....*....|....*....|....
gi 146134400 639 DEPTAGMDPCSRH-IVWNLLKYRKANRVTVFSTH 671
Cdd:cd03234 168 DEPTSGLDSFTALnLVSTLSQLARRNRIVILTIH 201
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
488-695 |
5.81e-26 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 109.27 E-value: 5.81e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 488 RKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEID--EMFEAR-KMIGICPQS 564
Cdd:cd03294 31 LKKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSrkELRELRrKKISMVFQS 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 565 DINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKlsVGIA--VLGNPKILLLDEPT 642
Cdd:cd03294 111 FALLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQR--VGLAraLAVDPDILLMDEAF 188
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 643 AGMDPCSRHIVWN-LLK-YRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVG 695
Cdd:cd03294 189 SALDPLIRREMQDeLLRlQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVG 243
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
1290-1521 |
8.07e-26 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 107.59 E-value: 8.07e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKKdFLHSrkttkvatkyISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG--DYGSHSS 1367
Cdd:cd03261 1 IELRGLTKSFGGRT-VLKG----------VDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDgeDISGLSE 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1368 EDDESIKC-MGYCPQTNPLWPDLT--------LQEHFEiygavkgMSPGDMKEVISRITKALDLKEhlqkTVKKLPA--- 1435
Cdd:cd03261 70 AELYRLRRrMGMLFQSGALFDSLTvfenvafpLREHTR-------LSEEEIREIVLEKLEAVGLRG----AEDLYPAels 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1436 -GIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCI 1514
Cdd:cd03261 139 gGMKKRVALARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAE 218
|
....*..
gi 146134400 1515 GTVQHLK 1521
Cdd:cd03261 219 GTPEELR 225
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
1289-1517 |
8.13e-26 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 107.86 E-value: 8.13e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1289 AIMVCNLHKEY-------DDKKDFLHSRKTTKVATKY----ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI 1357
Cdd:COG1134 4 MIEVENVSKSYrlyhepsRSLKELLLRRRRTRREEFWalkdVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1358 -------FLGDYGS--HsseddesikcmgycpqtnplwPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQK 1428
Cdd:COG1134 84 evngrvsALLELGAgfH---------------------PELTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFIDQ 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1429 TVKKLPAGIKRKLCFALSMLGNPQVTLLDEP-STGmDP----RAKQHMwrairTAFKNKKRAALLTTHYMEEAEAVCDRV 1503
Cdd:COG1134 143 PVKTYSSGMRARLAFAVATAVDPDILLVDEVlAVG-DAafqkKCLARI-----RELRESGRTVIFVSHSMGAVRRLCDRA 216
|
250
....*....|....
gi 146134400 1504 AIMVSGQLRCIGTV 1517
Cdd:COG1134 217 IWLEKGRLVMDGDP 230
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
1319-1522 |
9.49e-26 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 107.38 E-value: 9.49e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshsseDDESIKCM----------GYCPQTNPLWPD 1388
Cdd:COG0410 22 VSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRF---------DGEDITGLpphriarlgiGYVPEGRRIFPS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1389 LTLQEHFEIyGAVKGMSPGDMKEVISRItkaLD----LKEHLqktvkKLPAGikrklcfALS-----ML-------GNPQ 1452
Cdd:COG0410 93 LTVEENLLL-GAYARRDRAEVRADLERV---YElfprLKERR-----RQRAG-------TLSggeqqMLaigralmSRPK 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1453 VTLLDEPSTGMDPRAKQHMWRAIRTaFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKS 1522
Cdd:COG0410 157 LLLLDEPSLGLAPLIVEEIFEIIRR-LNREGVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAELLA 225
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
1319-1523 |
1.44e-25 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 107.04 E-value: 1.44e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshsseDDESIKCM-------GYCPQTNPLWPDLTL 1391
Cdd:cd03299 18 VSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILL---------NGKDITNLppekrdiSYVPQNYALFPHMTV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1392 QEHFEiYG--AVKGMSPGDMKEVIsRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQ 1469
Cdd:cd03299 89 YKNIA-YGlkKRKVDKKEIERKVL-EIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKE 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 146134400 1470 HMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSK 1523
Cdd:cd03299 167 KLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKK 220
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
474-696 |
1.83e-25 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 107.87 E-value: 1.83e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 474 GKEAIRISGIQKSYRKKTENVE--ALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEM 551
Cdd:PRK13633 1 MNEMIKCKNVSYKYESNEESTEklALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEENL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 552 FEARKMIGICPQSDINFDVLT-VEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVL 630
Cdd:PRK13633 81 WDIRNKAGMVFQNPDNQIVATiVEEDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILA 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 631 GNPKILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEAdILADRKAVISQGMLKCVGS 696
Cdd:PRK13633 161 MRPECIIFDEPTAMLDPSGRREVVNTIKelNKKYGITIILITHYMEEA-VEADRIIVMDSGKVVMEGT 227
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
496-689 |
3.63e-25 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 106.76 E-value: 3.63e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 496 ALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEiDEMFEARKMIGICPQ--------SDIN 567
Cdd:PRK13648 24 TLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITD-DNFEKLRKHIGIVFQnpdnqfvgSIVK 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 568 FDVLTVEENLSIlasikgiPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSV-GIAVLgNPKILLLDEPTAGMD 646
Cdd:PRK13648 103 YDVAFGLENHAV-------PYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIaGVLAL-NPSVIILDEATSMLD 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 146134400 647 PCSRHIVWNLLKYRKANR-VTVFS-THFMDEAdILADRKAVISQG 689
Cdd:PRK13648 175 PDARQNLLDLVRKVKSEHnITIISiTHDLSEA-MEADHVIVMNKG 218
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
492-676 |
3.77e-25 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 104.43 E-value: 3.77e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 492 ENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGhrvSEID----EMFEARKMIGICPQS-DI 566
Cdd:TIGR01166 3 GGPEVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDG---EPLDysrkGLLERRQRVGLVFQDpDD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 567 NFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMD 646
Cdd:TIGR01166 80 QLFAADVDQDVAFGPLNLGLSEAEVERRVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLDEPTAGLD 159
|
170 180 190
....*....|....*....|....*....|.
gi 146134400 647 PCSRHIVWNLL-KYRKANRVTVFSTHFMDEA 676
Cdd:TIGR01166 160 PAGREQMLAILrRLRAEGMTVVISTHDVDLA 190
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
478-689 |
3.79e-25 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 108.70 E-value: 3.79e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRkkteNVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIyGHRVSEIDEMFEARKm 557
Cdd:COG1118 3 IEVRNISKRFG----SFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVL-NGRDLFTNLPPRERR- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQsdiNFDV---LTVEENLSILASIKGIPANNIIQEVQKvLLDL-DMQAIKD---NQakkLSGGQK------RKLS 624
Cdd:COG1118 77 VGFVFQ---HYALfphMTVAENIAFGLRVRPPSKAEIRARVEE-LLELvQLEGLADrypSQ---LSGGQRqrvalaRALA 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 625 VgiavlgNPKILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADILADRKAVISQG 689
Cdd:COG1118 150 V------EPEVLLLDEPFGALDAKVRKELRRWLRrlHDELGGTTVFVTHDQEEALELADRVVVMNQG 210
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
477-728 |
4.02e-25 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 108.25 E-value: 4.02e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYR-----------------KKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFAS 539
Cdd:COG4586 1 IIEVENLSKTYRvyekepglkgalkglfrREYREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 540 IYGHRVSEIDEMFeaRKMIGIcpqsdinfdV----------LTVEENLSILASIKGIPaNNIIQEVQKVLLD-LDMQAIK 608
Cdd:COG4586 81 VLGYVPFKRRKEF--ARRIGV---------VfgqrsqlwwdLPAIDSFRLLKAIYRIP-DAEYKKRLDELVElLDLGELL 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 609 DNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLK-YRKANRVTVF-STHFMDeaDI--LADRKA 684
Cdd:COG4586 149 DTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKeYNRERGTTILlTSHDMD--DIeaLCDRVI 226
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 146134400 685 VISQGMLKCVGSSIFLKSKWGIGYRLSMYIDRYCATESLSSLVR 728
Cdd:COG4586 227 VIDHGRIIYDGSLEELKERFGPYKTIVLELAEPVPPLELPRGGE 270
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
493-691 |
4.03e-25 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 105.18 E-value: 4.03e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 493 NVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEA--RKMIGICPQSDINFDV 570
Cdd:cd03292 13 GTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPylRRKIGVVFQDFRLLPD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 571 LTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSR 650
Cdd:cd03292 93 RNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPDTT 172
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 146134400 651 HIVWNLLK-YRKANRVTVFSTHFMDEADILADRKAVISQGML 691
Cdd:cd03292 173 WEIMNLLKkINKAGTTVVVATHAKELVDTTRHRVIALERGKL 214
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
1294-1511 |
4.33e-25 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 105.28 E-value: 4.33e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYDDKKDFLHsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI-FLGDYGSHSSEDDES 1372
Cdd:cd03257 6 NLSVSFPTGGGSVK-------ALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIiFDGKDLLKLSRRLRK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1373 I--KCMGYCPQtNP---LWPDLTLQEHFE--IYGAVKGMSPGDMKEVISRITKALDLKEHLqktVKKLPA----GIKRKL 1441
Cdd:cd03257 79 IrrKEIQMVFQ-DPmssLNPRMTIGEQIAepLRIHGKLSKKEARKEAVLLLLVGVGLPEEV---LNRYPHelsgGQRQRV 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1442 CFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:cd03257 155 AIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKI 224
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
494-647 |
4.53e-25 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 106.28 E-value: 4.53e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 494 VEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDG---FA--SIYGHRVSEIdemfeARKmiGIC-----PQ 563
Cdd:COG0411 17 LVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGrilFDgrDITGLPPHRI-----ARL--GIArtfqnPR 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 564 SdinFDVLTVEENL----------SILASIKGIPAN-----NIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIA 628
Cdd:COG0411 90 L---FPELTVLENVlvaaharlgrGLLAALLRLPRArreerEARERAEELLERVGLADRADEPAGNLSYGQQRRLEIARA 166
|
170
....*....|....*....
gi 146134400 629 VLGNPKILLLDEPTAGMDP 647
Cdd:COG0411 167 LATEPKLLLLDEPAAGLNP 185
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
497-703 |
9.73e-25 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 104.73 E-value: 9.73e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGhrvSEIDEMFEARKMIGICPQSDINFDVLTVEEN 576
Cdd:cd03299 15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNG---KDITNLPPEKRDISYVPQNYALFPHMTVYKN 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 577 LSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNL 656
Cdd:cd03299 92 IAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEKLREE 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 146134400 657 LK-YRKANRVTVFS-THFMDEADILADRKAVISQGMLKCVGS--SIFLKSK 703
Cdd:cd03299 172 LKkIRKEFGVTVLHvTHDFEEAWALADKVAIMLNGKLIQVGKpeEVFKKPK 222
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
1294-1515 |
1.85e-24 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 103.38 E-value: 1.85e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYDDKKDFLHSRKTTKVATKY-----------ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIflgdy 1362
Cdd:cd03220 5 NVSKSYPTYKGGSSSLKKLGILGRKgevgefwalkdVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTV----- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1363 gshssEDDESIKCM-----GycpqtnpLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGI 1437
Cdd:cd03220 80 -----TVRGRVSSLlglggG-------FNPELTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGM 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 1438 KRKLCFALSMLGNPQVTLLDEP-STGmDPRAKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIG 1515
Cdd:cd03220 148 KARLAFAIATALEPDILLIDEVlAVG-DAAFQEKCQRRLR-ELLKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
1312-1515 |
2.27e-24 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 102.72 E-value: 2.27e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1312 TKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYcpQTNPLWPDLTL 1391
Cdd:cd03301 12 NVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKDRDIAMVF--QNYALYPHMTV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1392 QEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHM 1471
Cdd:cd03301 90 YDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSNLDAKLRVQM 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 146134400 1472 WRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIG 1515
Cdd:cd03301 170 RAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1286-1516 |
2.30e-24 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 106.72 E-value: 2.30e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1286 EKPAIMVCNLHKEYDDKkdflhsrkttkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygsh 1365
Cdd:COG3842 2 AMPALELENVSKRYGDV-----------TALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILL------ 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1366 sseDDESIKC-------MGYCPQTNPLWPDLTLQEHfeI-YG-AVKGMSPGDMKEvisRITKALD---LKEHLQKTVKKL 1433
Cdd:COG3842 65 ---DGRDVTGlppekrnVGMVFQDYALFPHLTVAEN--VaFGlRMRGVPKAEIRA---RVAELLElvgLEGLADRYPHQL 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1434 PAG------IKRklcfALSMlgNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMV 1507
Cdd:COG3842 137 SGGqqqrvaLAR----ALAP--EPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMN 210
|
....*....
gi 146134400 1508 SGQLRCIGT 1516
Cdd:COG3842 211 DGRIEQVGT 219
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
477-696 |
2.54e-24 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 106.32 E-value: 2.54e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIdemfEAR- 555
Cdd:PRK10851 2 SIEIANIKKSF----GRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRL----HARd 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 556 KMIGICPQSDINFDVLTVEEN----LSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLG 631
Cdd:PRK10851 74 RKVGFVFQHYALFRHMTVFDNiafgLTVLPRRERPNAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAV 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146134400 632 NPKILLLDEPTAGMDPCSRHIV--W-----NLLKYrkanrVTVFSTHFMDEADILADRKAVISQGMLKCVGS 696
Cdd:PRK10851 154 EPQILLLDEPFGALDAQVRKELrrWlrqlhEELKF-----TSVFVTHDQEEAMEVADRVVVMSQGNIEQAGT 220
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
1319-1511 |
2.93e-24 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 102.34 E-value: 2.93e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSeddESIKCMGYCPQ-------TNPLWPDLTL 1391
Cdd:cd03226 19 LSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAK---ERRKSIGYVMQdvdyqlfTDSVREELLL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1392 qehfeiyGAvkgMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHM 1471
Cdd:cd03226 96 -------GL---KELDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDYKNMERV 165
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 146134400 1472 WRAIRTAfKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:cd03226 166 GELIREL-AAQGKAVIVITHDYEFLAKVCDRVLLLANGAI 204
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
1325-1515 |
3.53e-24 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 102.37 E-value: 3.53e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1325 KGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESI----KCMGYCPQTNPLWPDLTLQEHFEiYGA 1400
Cdd:cd03297 22 NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDSRKKINLppqqRKIGLVFQQYALFPHLNVRENLA-FGL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1401 vKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFK 1480
Cdd:cd03297 101 -KRKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPELKQIKK 179
|
170 180 190
....*....|....*....|....*....|....*
gi 146134400 1481 NKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIG 1515
Cdd:cd03297 180 NLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
1290-1516 |
4.11e-24 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 102.70 E-value: 4.11e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKkdflhsrkttkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshsseD 1369
Cdd:cd03300 1 IELENVSKFYGGF-----------VALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILL---------D 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 DESI-------KCMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLC 1442
Cdd:cd03300 61 GKDItnlpphkRPVNTVFQNYALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVA 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 146134400 1443 FALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGT 1516
Cdd:cd03300 141 IARALVNEPKVLLLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGT 214
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1288-1521 |
4.18e-24 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 102.75 E-value: 4.18e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1288 PAIMVCNLHKEYDDK---KDflhsrkttkvatkyISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG--DY 1362
Cdd:COG1127 4 PMIEVRNLTKSFGDRvvlDG--------------VSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDgqDI 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1363 GSHSSEDDESI-KCMGYCPQTNPLWPDLT--------LQEHFeiygavkGMSPGDMKEVISRITKALDLKEHLqktvKKL 1433
Cdd:COG1127 70 TGLSEKELYELrRRIGMLFQGGALFDSLTvfenvafpLREHT-------DLSEAEIRELVLEKLELVGLPGAA----DKM 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1434 PA----GIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQ---HMWRAIRTAFKNkkrAALLTTHYMEEAEAVCDRVAIM 1506
Cdd:COG1127 139 PSelsgGMRKRVALARALALDPEILLYDEPTAGLDPITSAvidELIRELRDELGL---TSVVVTHDLDSAFAIADRVAVL 215
|
250
....*....|....*
gi 146134400 1507 VSGQLRCIGTVQHLK 1521
Cdd:COG1127 216 ADGKIIAEGTPEELL 230
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1290-1520 |
4.30e-24 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 102.80 E-value: 4.30e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYddkkdflhsRKTTKVatKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshsseD 1369
Cdd:COG1137 4 LEAENLVKSY---------GKRTVV--KDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFL---------D 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 DESI----------KCMGYCPQTNPLWPDLTLQEHFEiygAVKGMSPGDmKEVISRITKALdLKE-HLQKtVKKLPA--- 1435
Cdd:COG1137 64 GEDIthlpmhkrarLGIGYLPQEASIFRKLTVEDNIL---AVLELRKLS-KKEREERLEEL-LEEfGITH-LRKSKAysl 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1436 --GIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAK---QHMwraIRTAfKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQ 1510
Cdd:COG1137 138 sgGERRRVEIARALATNPKFILLDEPFAGVDPIAVadiQKI---IRHL-KERGIGVLITDHNVRETLGICDRAYIISEGK 213
|
250
....*....|
gi 146134400 1511 LRCIGTVQHL 1520
Cdd:COG1137 214 VLAEGTPEEI 223
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
1294-1506 |
7.09e-24 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 101.78 E-value: 7.09e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYDDKKdflhsrkTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDesi 1373
Cdd:cd03293 5 NVSKTYGGGG-------GAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPGPD--- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1374 kcMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQV 1453
Cdd:cd03293 75 --RGYVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDV 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1454 TLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIM 1506
Cdd:cd03293 153 LLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVL 205
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
486-689 |
8.79e-24 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 101.51 E-value: 8.79e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 486 SYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDeMFEARKMIGICPQsD 565
Cdd:cd03245 9 SFSYPNQEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLD-PADLRRNIGYVPQ-D 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 566 INFDVLTVEENLS----------ILASIKGIPANNIiqeVQKVLLDLDMQaIKDnQAKKLSGGQKRKLSVGIAVLGNPKI 635
Cdd:cd03245 87 VTLFYGTLRDNITlgapladderILRAAELAGVTDF---VNKHPNGLDLQ-IGE-RGRGLSGGQRQAVALARALLNDPPI 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 636 LLLDEPTAGMDPCS-RHIVWNLLKYRkANRVTVFSTHFMDEADiLADRKAVISQG 689
Cdd:cd03245 162 LLLDEPTSAMDMNSeERLKERLRQLL-GDKTLIIITHRPSLLD-LVDRIIVMDSG 214
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
478-689 |
9.79e-24 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 101.99 E-value: 9.79e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYrkkTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEI--DEMFEAR 555
Cdd:TIGR02315 2 LEVENLSKVY---PNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLrgKKLRKLR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 556 KMIGICPQSDINFDVLTVEEN-----LSILASIKGIPANNIIQEVQKVLLDLDMQAIKD---NQAKKLSGGQKRKLSVGI 627
Cdd:TIGR02315 79 RRIGMIFQHYNLIERLTVLENvlhgrLGYKPTWRSLLGRFSEEDKERALSALERVGLADkayQRADQLSGGQQQRVAIAR 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 146134400 628 AVLGNPKILLLDEPTAGMDPCSRHIVWNLLKY--RKANRVTVFSTHFMDEADILADRKAVISQG 689
Cdd:TIGR02315 159 ALAQQPDLILADEPIASLDPKTSKQVMDYLKRinKEDGITVIINLHQVDLAKKYADRIVGLKAG 222
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
489-689 |
1.39e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 102.48 E-value: 1.39e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 489 KKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEiDEMFEARKMIGICPQS-DIN 567
Cdd:PRK13642 15 EKESDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTA-ENVWNLRRKIGMVFQNpDNQ 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 568 FDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDP 647
Cdd:PRK13642 94 FVGATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDP 173
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 146134400 648 CSRHIVWNLL-KYRKANRVTVFS-THFMDEAdILADRKAVISQG 689
Cdd:PRK13642 174 TGRQEIMRVIhEIKEKYQLTVLSiTHDLDEA-ASSDRILVMKAG 216
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
478-689 |
1.71e-23 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 100.76 E-value: 1.71e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTEnveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMfEARKM 557
Cdd:cd03254 3 IEFENVNFSYDEKKP---VLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRK-SLRSM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVlTVEENLS----------ILASIKGIPANNIIQEVQKvllDLDMQAikDNQAKKLSGGQKRKLSVGI 627
Cdd:cd03254 79 IGVVLQDTFLFSG-TIMENIRlgrpnatdeeVIEAAKEAGAHDFIMKLPN---GYDTVL--GENGGNLSQGERQLLAIAR 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 628 AVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMD---EAD--ILADRKAVISQG 689
Cdd:cd03254 153 AMLRDPKILILDEATSNIDTETEKLIQEALEKLMKGRTSIIIAHRLStikNADkiLVLDDGKIIEEG 219
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
1314-1516 |
2.22e-23 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 98.27 E-value: 2.22e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1314 VATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYgshsseddesikcmgycpqtnplwpdltlqe 1393
Cdd:cd03216 14 KALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGK------------------------------- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1394 hfeiygAVKGMSPGDMKEviSRITkaldlkehlqkTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWR 1473
Cdd:cd03216 63 ------EVSFASPRDARR--AGIA-----------MVYQLSVGERQMVEIARALARNARLLILDEPTAALTPAEVERLFK 123
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 146134400 1474 AIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGqlRCIGT 1516
Cdd:cd03216 124 VIR-RLRAQGVAVIFISHRLDEVFEIADRVTVLRDG--RVVGT 163
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
478-689 |
2.57e-23 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 98.44 E-value: 2.57e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIqkSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMfEARKM 557
Cdd:cd03246 1 LEVENV--SFRYPGAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPN-ELGDH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDvltveenlsilASIkgipANNIiqevqkvlldldmqaikdnqakkLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:cd03246 78 VGYLPQDDELFS-----------GSI----AENI-----------------------LSGGQRQRLGLARALYGNPRILV 119
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLKYRKANRVT-VFSTHFMdEADILADRKAVISQG 689
Cdd:cd03246 120 LDEPNSHLDVEGERALNQAIAALKAAGATrIVIAHRP-ETLASADRILVLEDG 171
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
476-675 |
2.75e-23 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 100.93 E-value: 2.75e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 476 EAIRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGF-ASIYGHRVSEIDeMFEA 554
Cdd:COG1119 2 PLLELRNVTVRRGGKT----ILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNdVRLFGERRGGED-VWEL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 555 RKMIGIC-PQSDINFDV-LTVEEnlSIL----ASIkGIPAN---NIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSV 625
Cdd:COG1119 77 RKRIGLVsPALQLRFPRdETVLD--VVLsgffDSI-GLYREptdEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLI 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 146134400 626 GIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKY--RKANRVTVFSTHFMDE 675
Cdd:COG1119 154 ARALVKDPELLILDEPTAGLDLGARELLLALLDKlaAEGAPTLVLVTHHVEE 205
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
483-689 |
3.56e-23 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 101.31 E-value: 3.56e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 483 IQKSYRKKTEnveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVS-EIDEMFEARKMIGIC 561
Cdd:PRK13639 7 LKYSYPDGTE---ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKyDKKSLLEVRKTVGIV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 562 PQ-SDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSV-GIAVLgNPKILLLD 639
Cdd:PRK13639 84 FQnPDDQLFAPTVEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIaGILAM-KPEIIVLD 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 146134400 640 EPTAGMDPCSRHIVWNLLKYRKANRVT-VFSTHFMDEADILADRKAVISQG 689
Cdd:PRK13639 163 EPTSGLDPMGASQIMKLLYDLNKEGITiIISTHDVDLVPVYADKVYVMSDG 213
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
478-647 |
5.67e-23 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 99.68 E-value: 5.67e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVS----EIDEMfe 553
Cdd:COG1126 2 IEIENLHKSF----GDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTdskkDINKL-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 554 aRKMIGICPQSdIN-FDVLTVEENLsILASIK--GIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQK-RklsVGIA- 628
Cdd:COG1126 76 -RRKVGMVFQQ-FNlFPHLTVLENV-TLAPIKvkKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQqR---VAIAr 149
|
170 180
....*....|....*....|.
gi 146134400 629 --VLgNPKILLLDEPTAGMDP 647
Cdd:COG1126 150 alAM-EPKVMLFDEPTSALDP 169
|
|
| type_I_sec_LssB |
TIGR03375 |
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ... |
460-689 |
6.10e-23 |
|
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 106.10 E-value: 6.10e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 460 SLNEIVE-----PVSSEFIGKEAIR--ISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCP 532
Cdd:TIGR03375 437 SLDELMQlpverPEGTRFLHRPRLQgeIEFRNVSFAYPGQETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQ 516
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 533 PSDGFASIYGHRVSEIDeMFEARKMIGICPQsDInfdVL---TVEENL----------SILASIKGIPANNIIQEVQKvl 599
Cdd:TIGR03375 517 PTEGSVLLDGVDIRQID-PADLRRNIGYVPQ-DP---RLfygTLRDNIalgapyaddeEILRAAELAGVTEFVRRHPD-- 589
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 600 lDLDMQAIKDNQAkkLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADiL 679
Cdd:TIGR03375 590 -GLDMQIGERGRS--LSGGQRQAVALARALLRDPPILLLDEPTSAMDNRSEERFKDRLKRWLAGKTLVLVTHRTSLLD-L 665
|
250
....*....|
gi 146134400 680 ADRKAVISQG 689
Cdd:TIGR03375 666 VDRIIVMDNG 675
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
459-682 |
7.98e-23 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 104.68 E-value: 7.98e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 459 ISLNEIVEPVSSEFIGKEA--IRISGIQKSYRKKTEnveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDG 536
Cdd:TIGR02857 301 LDAAPRPLAGKAPVTAAPAssLEFSGVSVAYPGRRP---ALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEG 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 537 FASIYGHRVSEIDEMFeARKMIGICPQSDINFDVlTVEENlsILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKK-- 614
Cdd:TIGR02857 378 SIAVNGVPLADADADS-WRDQIAWVPQHPFLFAG-TIAEN--IRLARPDASDAEIREALERAGLDEFVAALPQGLDTPig 453
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 615 -----LSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSR-HIVWNLLKYRKaNRVTVFSTHfmDEADI-LADR 682
Cdd:TIGR02857 454 eggagLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEaEVLEALRALAQ-GRTVLLVTH--RLALAaLADR 525
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
497-704 |
9.09e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 100.29 E-value: 9.09e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRV---SEIDEMFEARKMIGICPQsdinFDVLTV 573
Cdd:PRK13641 23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHItpeTGNKNLKKLRKKVSLVFQ----FPEAQL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 574 EENlSILASIKGIPAN----------NIIQEVQKVLLDLDMQaikDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTA 643
Cdd:PRK13641 99 FEN-TVLKDVEFGPKNfgfsedeakeKALKWLKKVGLSEDLI---SKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAA 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 146134400 644 GMDPCSRHIVWNLLK-YRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGS--SIFLKSKW 704
Cdd:PRK13641 175 GLDPEGRKEMMQLFKdYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASpkEIFSDKEW 238
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
478-695 |
1.03e-22 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 104.10 E-value: 1.03e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKM 557
Cdd:PRK09700 6 ISMAGIGKSF----GPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSI----LASIKGIPA---NNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVL 630
Cdd:PRK09700 82 IGIIYQELSVIDELTVLENLYIgrhlTKKVCGVNIidwREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLM 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 631 GNPKILLLDEPTAGM-DPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVG 695
Cdd:PRK09700 162 LDAKVIIMDEPTSSLtNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSG 227
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
477-689 |
1.24e-22 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 99.81 E-value: 1.24e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTEnveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEmFEARK 556
Cdd:PRK13647 4 IIEVEDLHFRYKDGTK---ALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENE-KWVRS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQS-DINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKI 635
Cdd:PRK13647 80 KVGLVFQDpDDQVFSSTVWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDV 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 636 LLLDEPTAGMDPCSRHIVWNLL-KYRKANRVTVFSTHFMDEADILADRKAVISQG 689
Cdd:PRK13647 160 IVLDEPMAYLDPRGQETLMEILdRLHNQGKTVIVATHDVDLAAEWADQVIVLKEG 214
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
1319-1515 |
1.64e-22 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 96.35 E-value: 1.64e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQtnplwpdltlqehfeiy 1398
Cdd:cd03214 18 LSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARKIAYVPQ----------------- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1399 gavkgmspgdmkevISRITKALDLKEhlqKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTA 1478
Cdd:cd03214 81 --------------ALELLGLAHLAD---RPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQIELLELLRRL 143
|
170 180 190
....*....|....*....|....*....|....*..
gi 146134400 1479 FKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIG 1515
Cdd:cd03214 144 ARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
477-682 |
3.00e-22 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 102.40 E-value: 3.00e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRkkteNVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVsEIDEMFEARK 556
Cdd:COG1129 4 LLEMRGISKSFG----GVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPV-RFRSPRDAQA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 M-IGICPQsDIN-FDVLTVEENLSI---LASIKGIPANNIIQEVQKVL----LDLDMQAIkdnqAKKLSGGQkRKLsVGI 627
Cdd:COG1129 79 AgIAIIHQ-ELNlVPNLSVAENIFLgrePRRGGLIDWRAMRRRARELLarlgLDIDPDTP----VGDLSVAQ-QQL-VEI 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 628 --AVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVT-VFSTHFMDEADILADR 682
Cdd:COG1129 152 arALSRDARVLILDEPTASLTEREVERLFRIIRRLKAQGVAiIYISHRLDEVFEIADR 209
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
478-696 |
3.71e-22 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 100.68 E-value: 3.71e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMfeaRKM 557
Cdd:PRK11607 20 LEIRNLTKSF----DGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPY---QRP 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:PRK11607 93 INMMFQSYALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLL 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 638 LDEPTAGMDPCSR----HIVWNLLKYRKANRVTVfsTHFMDEADILADRKAVISQGMLKCVGS 696
Cdd:PRK11607 173 LDEPMGALDKKLRdrmqLEVVDILERVGVTCVMV--THDQEEAMTMAGRIAIMNRGKFVQIGE 233
|
|
| COG4674 |
COG4674 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
496-696 |
6.46e-22 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443710 [Multi-domain] Cd Length: 250 Bit Score: 96.72 E-value: 6.46e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 496 ALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQSDINFDVLTVEE 575
Cdd:COG4674 25 ALNDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGGTDLTGLDEHEIARLGIGRKFQKPTVFEELTVFE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 576 NL--------SILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDP 647
Cdd:COG4674 105 NLelalkgdrGVFASLFARLTAEERDRIEEVLETIGLTDKADRLAGLLSHGQKQWLEIGMLLAQDPKLLLLDEPVAGMTD 184
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 146134400 648 CSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGS 696
Cdd:COG4674 185 AETERTAELLKSLAGKHSVVVVEHDMEFVRQIARKVTVLHQGSVLAEGS 233
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1287-1520 |
6.80e-22 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 101.52 E-value: 6.80e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1287 KPAIMVCNLHKEYddkkdflhsRKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPT---SGKIFLGdyG 1363
Cdd:COG1123 2 TPLLEVRDLSVRY---------PGGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLD--G 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1364 SHSSEDDESI--KCMGYCPQtNP---LWPdLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIK 1438
Cdd:COG1123 71 RDLLELSEALrgRRIGMVFQ-DPmtqLNP-VTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1439 RKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQ 1518
Cdd:COG1123 149 QRVAIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPE 228
|
..
gi 146134400 1519 HL 1520
Cdd:COG1123 229 EI 230
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
1294-1511 |
7.14e-22 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 95.63 E-value: 7.14e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYddkkdflHSRKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshsseDDESI 1373
Cdd:cd03255 5 NLSKTY-------GGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRV---------DGTDI 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1374 KCM-------------GYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRK 1440
Cdd:cd03255 69 SKLsekelaafrrrhiGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQR 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 1441 LCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAvCDRVAIMVSGQL 1511
Cdd:cd03255 149 VAIARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAEY-ADRIIELRDGKI 218
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
486-710 |
7.57e-22 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 96.40 E-value: 7.57e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 486 SYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFeARKMIGICPQSD 565
Cdd:cd03252 7 RFRYKPDGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAW-LRRQVGVVLQEN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 566 INFDvLTVEENLS----------ILASIKGIPANNIIQEvqkvlLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKI 635
Cdd:cd03252 86 VLFN-RSIRDNIAladpgmsmerVIEAAKLAGAHDFISE-----LPEGYDTIVGEQGAGLSGGQRQRIAIARALIHNPRI 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 636 LLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMdEADILADRKAVISQGMLKCVGSSIFLKSKWGIGYRL 710
Cdd:cd03252 160 LIFDEATSALDYESEHAIMRNMHDICAGRTVIIIAHRL-STVKNADRIIVMEKGRIVEQGSHDELLAENGLYAYL 233
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
478-689 |
8.44e-22 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 95.29 E-value: 8.44e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKtenvEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVS----EIDEMfe 553
Cdd:cd03262 1 IEIKNLHKSFGDF----HVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTddkkNINEL-- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 554 aRKMIGICPQSDINFDVLTVEENLsILASIK--GIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLG 631
Cdd:cd03262 75 -RQKVGMVFQQFNLFPHLTVLENI-TLAPIKvkGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAM 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 632 NPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVT-VFSTHFMDEADILADRKAVISQG 689
Cdd:cd03262 153 NPKVMLFDEPTSALDPELVGEVLDVMKDLAEEGMTmVVVTHEMGFAREVADRVIFMDDG 211
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
478-710 |
9.65e-22 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 95.76 E-value: 9.65e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTENVeaLRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIdEMFEARKM 557
Cdd:cd03251 1 VEFKNVTFRYPGDGPPV--LRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDY-TLASLRRQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVlTVEENLS----------ILASIKGIPANNIIQEvqkvlLDLDMQAIKDNQAKKLSGGQKRKLSVGI 627
Cdd:cd03251 78 IGLVSQDVFLFND-TVAENIAygrpgatreeVEEAARAANAHEFIME-----LPEGYDTVIGERGVKLSGGQRQRIAIAR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 628 AVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTH----FMDeadilADRKAVISQGMLKCVGSSIFLKSK 703
Cdd:cd03251 152 ALLKDPPILILDEATSALDTESERLVQAALERLMKNRTTFVIAHrlstIEN-----ADRIVVLEDGKIVERGTHEELLAQ 226
|
....*..
gi 146134400 704 WGIGYRL 710
Cdd:cd03251 227 GGVYAKL 233
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
474-696 |
9.66e-22 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 98.00 E-value: 9.66e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 474 GKEAIRISGIQKSYRKKTEN-VEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASI------------ 540
Cdd:PRK13631 18 DDIILRVKNLYCVFDEKQENeLVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVgdiyigdkknnh 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 541 ---YGHRVSEIDEMFEARKMIGIC---PQSDINFDvlTVEENLSILASIKGIPANNIIQEVQKVL--LDLDMQAIkDNQA 612
Cdd:PRK13631 98 eliTNPYSKKIKNFKELRRRVSMVfqfPEYQLFKD--TIEKDIMFGPVALGVKKSEAKKLAKFYLnkMGLDDSYL-ERSP 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 613 KKLSGGQKRKLSV-GIAVLgNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFS-THFMDEADILADRKAVISQGM 690
Cdd:PRK13631 175 FGLSGGQKRRVAIaGILAI-QPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFViTHTMEHVLEVADEVIVMDKGK 253
|
....*.
gi 146134400 691 LKCVGS 696
Cdd:PRK13631 254 ILKTGT 259
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
512-697 |
1.02e-21 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 98.33 E-value: 1.02e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 512 LLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEmfeARKMIGICPQSDINFDVLTVEENLSILASIKGIPANNI 591
Cdd:TIGR01187 1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVPP---HLRHINMVFQSYALFPHMTVEENVAFGLKMRKVPRAEI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 592 IQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFS 669
Cdd:TIGR01187 78 KPRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKtiQEQLGITFVFV 157
|
170 180
....*....|....*....|....*...
gi 146134400 670 THFMDEADILADRKAVISQGMLKCVGSS 697
Cdd:TIGR01187 158 THDQEEAMTMSDRIAIMRKGKIAQIGTP 185
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
497-658 |
1.12e-21 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 101.66 E-value: 1.12e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPS---DGFASIYGHRVsEIDEMfeaRKMIGICPQSDINFDVLTV 573
Cdd:TIGR00955 41 LKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGvkgSGSVLLNGMPI-DAKEM---RAISAYVQQDDLFIPTLTV 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 574 EENLSILASIK---GIPANNIIQEVQKVLLDLDMQAIKD------NQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAG 644
Cdd:TIGR00955 117 REHLMFQAHLRmprRVTKKEKRERVDEVLQALGLRKCANtrigvpGRVKGLSGGERKRLAFASELLTDPPLLFCDEPTSG 196
|
170
....*....|....
gi 146134400 645 MDPCSRHIVWNLLK 658
Cdd:TIGR00955 197 LDSFMAYSVVQVLK 210
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
476-689 |
1.24e-21 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 96.47 E-value: 1.24e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 476 EAIRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDemfeAR 555
Cdd:COG4525 2 SMLTVRHVSVRYPGGGQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGPG----AD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 556 KmiGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKlsVGIA--VLGNP 633
Cdd:COG4525 78 R--GVVFQKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQR--VGIAraLAADP 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 634 KILLLDEPTAGMDPCSR-HIVWNLLKYRKANRVTVF-STHFMDEADILADRKAVISQG 689
Cdd:COG4525 154 RFLLMDEPFGALDALTReQMQELLLDVWQRTGKGVFlITHSVEEALFLATRLVVMSPG 211
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
475-703 |
2.80e-21 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 95.23 E-value: 2.80e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 475 KEAIRISGIQKSYRKKtenvEALRNLSFDIYEGQITALLGHSGTGKSTLM---NILCGLCP--PSDGFASIYGHRV-SEI 548
Cdd:PRK14239 3 EPILQVSDLSVYYNKK----KALNSVSLDFYPNEITALIGPSGSGKSTLLrsiNRMNDLNPevTITGSIVYNGHNIySPR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 549 DEMFEARKMIGICPQSDINFDvLTVEENLSILASIKGIPANNIIQE-VQKVLLDLDM-QAIKD---NQAKKLSGGQKRKL 623
Cdd:PRK14239 79 TDTVDLRKEIGMVFQQPNPFP-MSIYENVVYGLRLKGIKDKQVLDEaVEKSLKGASIwDEVKDrlhDSALGLSGGQQQRV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 624 SVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGS--SIFLK 701
Cdd:PRK14239 158 CIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDDYTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDtkQMFMN 237
|
..
gi 146134400 702 SK 703
Cdd:PRK14239 238 PK 239
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
477-647 |
3.44e-21 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 94.69 E-value: 3.44e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVS---EIDE--M 551
Cdd:COG4161 2 SIQLKNINCFY----GSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFDfsqKPSEkaI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 552 FEARKMIGICPQSDINFDVLTVEENLsILASIK--GIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAV 629
Cdd:COG4161 78 RLLRQKVGMVFQQYNLWPHLTVMENL-IEAPCKvlGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARAL 156
|
170
....*....|....*...
gi 146134400 630 LGNPKILLLDEPTAGMDP 647
Cdd:COG4161 157 MMEPQVLLFDEPTAALDP 174
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
480-658 |
4.32e-21 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 100.18 E-value: 4.32e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 480 ISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEA---RK 556
Cdd:PRK10535 7 LKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAqlrRE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKIL 636
Cdd:PRK10535 87 HFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVI 166
|
170 180
....*....|....*....|..
gi 146134400 637 LLDEPTAGMDPCSRHIVWNLLK 658
Cdd:PRK10535 167 LADEPTGALDSHSGEEVMAILH 188
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
483-696 |
4.73e-21 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 94.19 E-value: 4.73e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 483 IQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICP 562
Cdd:PRK10895 9 LAKAYKGRR----VVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARARRGIGYLP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 563 QSDINFDVLTVEENL-SILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEP 641
Cdd:PRK10895 85 QEASIFRRLSVYDNLmAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEP 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 642 TAGMDPCSRHIVWNLLKYRKANRVTVFST-HFMDEADILADRKAVISQGMLKCVGS 696
Cdd:PRK10895 165 FAGVDPISVIDIKRIIEHLRDSGLGVLITdHNVRETLAVCERAYIVSQGHLIAHGT 220
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
478-696 |
5.10e-21 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 96.94 E-value: 5.10e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEmfEARKm 557
Cdd:PRK09452 15 VELRGISKSF----DGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPA--ENRH- 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:PRK09452 88 VNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLL 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLKY--RKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGS 696
Cdd:PRK09452 168 LDESLSALDYKLRKQMQNELKAlqRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGT 228
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
1313-1523 |
5.17e-21 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 99.45 E-value: 5.17e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1313 KVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYgSHSSEDDESI-KCMGYCPQtNPLWPDLTL 1391
Cdd:COG4988 350 RPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGV-DLSDLDPASWrRQIAWVPQ-NPYLFAGTI 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1392 QEHFEIYGAvkGMSPGDMKEVIsRITKALDLkehlqktVKKLPAGI---------------KRKLCFALSMLGNPQVTLL 1456
Cdd:COG4988 428 RENLRLGRP--DASDEELEAAL-EAAGLDEF-------VAALPDGLdtplgeggrglsggqAQRLALARALLRDAPLLLL 497
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 1457 DEPSTGMDPRAKQHMWRAIRTAFKNkkRAALLTTHYMEEAEAvCDRVAIMVSGQLRCIGTVQHLKSK 1523
Cdd:COG4988 498 DEPTAHLDAETEAEILQALRRLAKG--RTVILITHRLALLAQ-ADRILVLDDGRIVEQGTHEELLAK 561
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
497-689 |
5.99e-21 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 93.68 E-value: 5.99e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSE--IDEMfearkmigICPQSDINFDVLTVE 574
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEpgPDRM--------VVFQNYSLLPWLTVR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 575 ENLSiLASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKK---LSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSR- 650
Cdd:TIGR01184 73 ENIA-LAVDRVLPDLSKSERRAIVEEHIALVGLTEAADKRpgqLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRg 151
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 146134400 651 HIVWNLLKYRKANRVT-VFSTHFMDEADILADRKAVISQG 689
Cdd:TIGR01184 152 NLQEELMQIWEEHRVTvLMVTHDVDEALLLSDRVVMLTNG 191
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
478-712 |
1.31e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 93.93 E-value: 1.31e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTE-NVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIyGHRV--SEIDE--MF 552
Cdd:PRK13634 3 ITFQKVEHRYQYKTPfERRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTI-GERVitAGKKNkkLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 553 EARKMIGIC---PQSDInFDVlTVEENLSILASIKGIPANNIIQEVQKV--LLDLDmQAIKDNQAKKLSGGQKRKlsVGI 627
Cdd:PRK13634 82 PLRKKVGIVfqfPEHQL-FEE-TVEKDICFGPMNFGVSEEDAKQKAREMieLVGLP-EELLARSPFELSGGQMRR--VAI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 628 A-VLG-NPKILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGS--SIFLK 701
Cdd:PRK13634 157 AgVLAmEPEVLVLDEPTAGLDPKGRKEMMEMFYklHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTprEIFAD 236
|
250
....*....|.
gi 146134400 702 SKWGIGYRLSM 712
Cdd:PRK13634 237 PDELEAIGLDL 247
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
493-710 |
1.39e-20 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 92.68 E-value: 1.39e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 493 NVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDeMFEARKMIGICPQSdinfdvlT 572
Cdd:cd03253 13 GRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVT-LDSLRRAIGVVPQD-------T 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 573 VEENLSILASIK-GIP-ANN--IIQEVQKVLLDLDMQAIKDNQAK-------KLSGGQKRKLSVGIAVLGNPKILLLDEP 641
Cdd:cd03253 85 VLFNDTIGYNIRyGRPdATDeeVIEAAKAAQIHDKIMRFPDGYDTivgerglKLSGGEKQRVAIARAILKNPPILLLDEA 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 642 TAGMD-PCSRHIVWNLLKYRKaNRVTVFSTHFMDEAdILADRKAVISQGMLKCVGSSIFLKSKWGIGYRL 710
Cdd:cd03253 165 TSALDtHTEREIQAALRDVSK-GRTTIVIAHRLSTI-VNADKIIVLKDGRIVERGTHEELLAKGGLYAEM 232
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
1319-1510 |
1.75e-20 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 90.13 E-value: 1.75e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYgSHSSEDDESI-KCMGYCPQTNPLWPDlTLqehfei 1397
Cdd:cd03228 21 VSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGV-DLRDLDLESLrKNIAYVPQDPFLFSG-TI------ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1398 ygavkgmspgdmKEVIsritkaldlkehlqktvkkLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRT 1477
Cdd:cd03228 93 ------------RENI-------------------LSGGQRQRIAIARALLRDPPILILDEATSALDPETEALILEALRA 141
|
170 180 190
....*....|....*....|....*....|...
gi 146134400 1478 AFKNkkRAALLTTHYMEEAEAvCDRVAIMVSGQ 1510
Cdd:cd03228 142 LAKG--KTVIVIAHRLSTIRD-ADRIIVLDDGR 171
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
499-689 |
1.84e-20 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 91.40 E-value: 1.84e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 499 NLSFD--IYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEmfeARKMIGICPQSDINFDVLTVEEN 576
Cdd:cd03298 14 PMHFDltFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPP---ADRPVSMLFQENNLFAHLTVEQN 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 577 LSiLASIKGIPANNIIQE-VQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWN 655
Cdd:cd03298 91 VG-LGLSPGLKLTAEDRQaIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLD 169
|
170 180 190
....*....|....*....|....*....|....*.
gi 146134400 656 L-LKYRKANRVTV-FSTHFMDEADILADRKAVISQG 689
Cdd:cd03298 170 LvLDLHAETKMTVlMVTHQPEDAKRLAQRVVFLDNG 205
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
1308-1520 |
2.43e-20 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 91.98 E-value: 2.43e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1308 SRKTTKVATKYISFCVKKGEILGLLGPNGAGKST---VINTLvgdVEPTSGKIFLGdyGSHSSEDDESI--KCMGYCPQT 1382
Cdd:cd03295 9 RYGGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTtmkMINRL---IEPTSGEIFID--GEDIREQDPVElrRKIGYVIQQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1383 NPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDL--KEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPS 1460
Cdd:cd03295 84 IGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLdpAEFADRYPHELSGGQQQRVGVARALAADPPLLLMDEPF 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1461 TGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL 1520
Cdd:cd03295 164 GALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEI 223
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
478-691 |
2.45e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 93.31 E-value: 2.45e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTE-NVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYG---HRVSEIDEMFE 553
Cdd:PRK13646 3 IRFDNVSYTYQKGTPyEHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDitiTHKTKDKYIRP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 554 ARKMIGIC---PQSDINFDvlTVEENLSILASIKGIPANNIIQEVQKVLLDLDM-QAIKDNQAKKLSGGQKRKLSVGIAV 629
Cdd:PRK13646 83 VRKRIGMVfqfPESQLFED--TVEREIIFGPKNFKMNLDEVKNYAHRLLMDLGFsRDVMSQSPFQMSGGQMRKIAIVSIL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 146134400 630 LGNPKILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADILADRKAVISQGML 691
Cdd:PRK13646 161 AMNPDIIVLDEPTAGLDPQSKRQVMRLLKslQTDENKTIILVSHDMNEVARYADEVIVMKEGSI 224
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
478-689 |
2.79e-20 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 91.40 E-value: 2.79e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTENVeaLRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDeMFEARKM 557
Cdd:cd03244 3 IEFKNVSLRYRPNLPPV--LKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIG-LHDLRSR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVlTVEENL---------SILASIKGIPANNIIQEvQKVLLDLDMQAIKDNqakkLSGGQKRKLSVGIA 628
Cdd:cd03244 80 ISIIPQDPVLFSG-TIRSNLdpfgeysdeELWQALERVGLKEFVES-LPGGLDTVVEEGGEN----LSVGQRQLLCLARA 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 629 VLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTH----FMDeadilADRKAVISQG 689
Cdd:cd03244 154 LLRKSKILVLDEATASVDPETDALIQKTIREAFKDCTVLTIAHrldtIID-----SDRILVLDKG 213
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
478-710 |
2.87e-20 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 91.83 E-value: 2.87e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTEnVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDeMFEARKM 557
Cdd:cd03249 1 IEFKNVSFRYPSRPD-VPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLN-LRWLRSQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVlTVEENLSIlasikGipANNIIQEvqkvlldLDMQAIKD-------------------NQAKKLSGG 618
Cdd:cd03249 79 IGLVSQEPVLFDG-TIAENIRY-----G--KPDATDE-------EVEEAAKKanihdfimslpdgydtlvgERGSQLSGG 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 619 QKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMdeADIL-ADRKAVISQGMLKCVGSS 697
Cdd:cd03249 144 QKQRIAIARALLRNPKILLLDEATSALDAESEKLVQEALDRAMKGRTTIVIAHRL--STIRnADLIAVLQNGQVVEQGTH 221
|
250
....*....|...
gi 146134400 698 IFLKSKWGIGYRL 710
Cdd:cd03249 222 DELMAQKGVYAKL 234
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
478-689 |
4.02e-20 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 95.89 E-value: 4.02e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMfEARKM 557
Cdd:PRK15439 12 LCARSISKQY----SGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTPA-KAHQL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 -IGICPQSDINFDVLTVEENlsILAsikGIPAN--------NIIQEVQkVLLDLDMQA----IKDNQAKKLSGGQKRkls 624
Cdd:PRK15439 87 gIYLVPQEPLLFPNLSVKEN--ILF---GLPKRqasmqkmkQLLAALG-CQLDLDSSAgsleVADRQIVEILRGLMR--- 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 625 vgiavlgNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRV-TVFSTHFMDEADILADRKAVISQG 689
Cdd:PRK15439 158 -------DSRILILDEPTASLTPAETERLFSRIRELLAQGVgIVFISHKLPEIRQLADRISVMRDG 216
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
497-680 |
4.22e-20 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 90.62 E-value: 4.22e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPP---SDGFASIYGHRVSEIDEmfEARKmIGICPQSDINFDVLTV 573
Cdd:COG4136 17 LAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPafsASGEVLLNGRRLTALPA--EQRR-IGILFQDDLLFPHLSV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 574 EENLSiLASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPC----S 649
Cdd:COG4136 94 GENLA-FALPPTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDAAlraqF 172
|
170 180 190
....*....|....*....|....*....|.
gi 146134400 650 RHIVWNLLkyRKANRVTVFSTHfmDEADILA 680
Cdd:COG4136 173 REFVFEQI--RQRGIPALLVTH--DEEDAPA 199
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
1290-1518 |
4.37e-20 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 93.67 E-value: 4.37e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKKdflhsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG--DYGSHSS 1367
Cdd:COG1118 3 IEVRNISKRFGSFT-----------LLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNgrDLFTNLP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1368 EDDESIkcmGYCPQTNPLWPDLTLQEHfeI-YGA-VKGMSPGDMKEVISRITKALDLkEHLQktvKKLPAgikrklcfAL 1445
Cdd:COG1118 72 PRERRV---GFVFQHYALFPHMTVAEN--IaFGLrVRPPSKAEIRARVEELLELVQL-EGLA---DRYPS--------QL 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1446 S-----------ML-GNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRC 1513
Cdd:COG1118 135 SggqrqrvalarALaVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQ 214
|
....*
gi 146134400 1514 IGTVQ 1518
Cdd:COG1118 215 VGTPD 219
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
1323-1619 |
6.15e-20 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 93.26 E-value: 6.15e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1323 VKKGEILGLLGPNGAG--KSTVINTLVGdvePTSGKiFLGDYGSHSSEDDESIKCMG-YCPQTNPLWPDLTLQEHFEIYG 1399
Cdd:NF000106 36 VREGTVLGVLGP*GAA**RGALPAHV*G---PDAGR-RPWRF*TWCANRRALRRTIG*HRPVR*GRRESFSGRENLYMIG 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1400 AVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAF 1479
Cdd:NF000106 112 R*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMV 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1480 KNKKrAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGkGYFLEIKLKdwiENLEIDRLQREI-QYIFPNAS 1558
Cdd:NF000106 192 RDGA-TVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKVG-GRTLQIRPA---HAAELDRMVGAIaQAGLDGIA 266
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 1559 RQESFSSILAFKIPKEDVQSLSQSFAKLEEakRTFAIEEYSFSQATLEQVFVELTKEQEEE 1619
Cdd:NF000106 267 GATADHEDGVVNVPIVSDEQLSAVVGMLGE--RGFTISGHQHPSAQL*EVFLAITGQKTSE 325
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
478-696 |
6.20e-20 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 91.59 E-value: 6.20e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTEnveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKM 557
Cdd:PRK13644 2 IRLENVSYSYPDGTP---ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKLQGIRKL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQS-DINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKIL 636
Cdd:PRK13644 79 VGIVFQNpETQFVGRTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECL 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 637 LLDEPTAGMDPCS-RHIVWNLLKYRKANRVTVFSTHFMDEADIlADRKAVISQGMLKCVGS 696
Cdd:PRK13644 159 IFDEVTSMLDPDSgIAVLERIKKLHEKGKTIVYITHNLEELHD-ADRIIVMDRGKIVLEGE 218
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
1287-1459 |
6.60e-20 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 95.52 E-value: 6.60e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1287 KPAIMVCNLHKEYDDKKDFLHsrkttkvatkyISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGdygshs 1366
Cdd:COG0488 313 KKVLELEGLSKSYGDKTLLDD-----------LSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLG------ 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1367 seddESIKcMGYCPQTN-PLWPDLTLQEHfeiygaVKGMSPGDMKEVISRITKALDLK-EHLQKTVKKLPAGIKRKLCFA 1444
Cdd:COG0488 376 ----ETVK-IGYFDQHQeELDPDKTVLDE------LRDGAPGGTEQEVRGYLGRFLFSgDDAFKPVGVLSGGEKARLALA 444
|
170
....*....|....*
gi 146134400 1445 LSMLGNPQVTLLDEP 1459
Cdd:COG0488 445 KLLLSPPNVLLLDEP 459
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
1314-1525 |
7.12e-20 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 96.73 E-value: 7.12e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1314 VATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdYGSHSSEDD-ESIKCMGYCPQTNPLWPDLTLQ 1392
Cdd:NF033858 280 TAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWL--FGQPVDAGDiATRRRVGYMSQAFSLYGELTVR 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1393 EHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMW 1472
Cdd:NF033858 358 QNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFW 437
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 1473 RAI----R----TAFknkkraalLTTHYMEEAEAvCDRVAIMVSGQLRCIGTVQHLKSKFG 1525
Cdd:NF033858 438 RLLielsRedgvTIF--------ISTHFMNEAER-CDRISLMHAGRVLASDTPAALVAARG 489
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
495-689 |
7.37e-20 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 91.83 E-value: 7.37e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 495 EALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVS-EIDEMFEARKMIGICPQS-DINFDVLT 572
Cdd:PRK13636 20 HALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIDySRKGLMKLRESVGMVFQDpDNQLFSAS 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 573 VEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHI 652
Cdd:PRK13636 100 VYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSE 179
|
170 180 190
....*....|....*....|....*....|....*....
gi 146134400 653 VWNLLK--YRKANRVTVFSTHFMDEADILADRKAVISQG 689
Cdd:PRK13636 180 IMKLLVemQKELGLTIIIATHDIDIVPLYCDNVFVMKEG 218
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
477-696 |
7.58e-20 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 95.09 E-value: 7.58e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfaSIY--GHRVsEIDEMFEA 554
Cdd:COG3845 5 ALELRGITKRF----GGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSG--EILidGKPV-RIRSPRDA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 555 RKM-IGICPQsdiNF---DVLTVEENLsILASIKG----IPANNIIQEVQKVL----LDLDMQA-IKDnqakkLSGGQKR 621
Cdd:COG3845 78 IALgIGMVHQ---HFmlvPNLTVAENI-VLGLEPTkggrLDRKAARARIRELSerygLDVDPDAkVED-----LSVGEQQ 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 622 KlsVGI--AVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTV-FSTHFMDEADILADRKAVISQGmlKCVGS 696
Cdd:COG3845 149 R--VEIlkALYRGARILILDEPTAVLTPQEADELFEILRRLAAEGKSIiFITHKLREVMAIADRVTVLRRG--KVVGT 222
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
493-671 |
7.63e-20 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 89.55 E-value: 7.63e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 493 NVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRvSEIDEMFEARKMIGicPQSDINfDVLT 572
Cdd:PRK13539 14 GRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGD-IDDPDVAEACHYLG--HRNAMK-PALT 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 573 VEENLSILASIKGIPANNIIQevqkVLLDLDMQAIKDNQAKKLSGGQKRKLSvgIA---VLGNPkILLLDEPTAGMDPCS 649
Cdd:PRK13539 90 VAENLEFWAAFLGGEELDIAA----ALEAVGLAPLAHLPFGYLSAGQKRRVA--LArllVSNRP-IWILDEPTAALDAAA 162
|
170 180
....*....|....*....|...
gi 146134400 650 RHIVWNLLKYR-KANRVTVFSTH 671
Cdd:PRK13539 163 VALFAELIRAHlAQGGIVIAATH 185
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
1301-1520 |
8.74e-20 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 92.86 E-value: 8.74e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1301 DKKDFLHSRKTTK-----VATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFL-GDYGSHSSEDDESIk 1374
Cdd:PRK11432 2 TQKNFVVLKNITKrfgsnTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIdGEDVTHRSIQQRDI- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1375 CMGYcpQTNPLWPDLTLQEHFEiYG-AVKGMSPGDMKEvisRITKAL---DLKEHLQKTVKKLPAGIKRKLCFALSMLGN 1450
Cdd:PRK11432 81 CMVF--QSYALFPHMSLGENVG-YGlKMLGVPKEERKQ---RVKEALelvDLAGFEDRYVDQISGGQQQRVALARALILK 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1451 PQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL 1520
Cdd:PRK11432 155 PKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQEL 224
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
1295-1516 |
9.81e-20 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 91.17 E-value: 9.81e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1295 LHKEYDDKKDFLHSRKTTkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESI- 1373
Cdd:cd03294 20 LLAKGKSKEEILKKTGQT-VGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRe 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1374 ---KCMGYCPQTNPLWPDLTLQEHFEiYG-AVKGMSPgdmKEVISRITKALD---LKEHLQKTVKKLPAGIKRKLCFALS 1446
Cdd:cd03294 99 lrrKKISMVFQSFALLPHRTVLENVA-FGlEVQGVPR---AEREERAAEALElvgLEGWEHKYPDELSGGMQQRVGLARA 174
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1447 MLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGT 1516
Cdd:cd03294 175 LAVDPDILLMDEAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGT 244
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1285-1520 |
1.03e-19 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 94.97 E-value: 1.03e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1285 EEKPAIMVCNLHKEYDDKkdflhsRKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG--DY 1362
Cdd:COG1123 256 AAEPLLEVRNLSKRYPVR------GKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDgkDL 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1363 GSHSSEDDESI-KCMGYCPQtNP---LWPDLTLQEhfEIYGAVKGMSPGDMKEVISRITKALDL----KEHLQKTVKKLP 1434
Cdd:COG1123 330 TKLSRRSLRELrRRVQMVFQ-DPyssLNPRMTVGD--IIAEPLRLHGLLSRAERRERVAELLERvglpPDLADRYPHELS 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1435 AGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCI 1514
Cdd:COG1123 407 GGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVED 486
|
....*.
gi 146134400 1515 GTVQHL 1520
Cdd:COG1123 487 GPTEEV 492
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
1319-1511 |
1.09e-19 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 88.76 E-value: 1.09e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVG--DVEPTSGKIFlgdYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQEhfe 1396
Cdd:cd03213 28 VSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVL---INGRPLDKRSFRKIIGYVPQDDILHPTLTVRE--- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1397 iygavkgmspgdmkevisritkALDLKEHLqktvKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIR 1476
Cdd:cd03213 102 ----------------------TLMFAAKL----RGLSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLR 155
|
170 180 190
....*....|....*....|....*....|....*.
gi 146134400 1477 tAFKNKKRAALLTTHY-MEEAEAVCDRVAIMVSGQL 1511
Cdd:cd03213 156 -RLADTGRTIICSIHQpSSEIFELFDKLLLLSQGRV 190
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
494-689 |
1.20e-19 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 89.94 E-value: 1.20e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 494 VEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQSDINFDVLTV 573
Cdd:PRK11614 18 IQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKIMREAVAIVPEGRRVFSRMTV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 574 EENLSIlasiKGIPAN--NIIQEVQKVL-LDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSR 650
Cdd:PRK11614 98 EENLAM----GGFFAErdQFQERIKWVYeLFPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAPIII 173
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 146134400 651 HIVWNLLKYRKANRVTVFST-HFMDEADILADRKAVISQG 689
Cdd:PRK11614 174 QQIFDTIEQLREQGMTIFLVeQNANQALKLADRGYVLENG 213
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
477-647 |
1.46e-19 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 89.69 E-value: 1.46e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRV---SEIDE--M 551
Cdd:PRK11124 2 SIQLNGINCFY----GAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFdfsKTPSDkaI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 552 FEARKMIGICPQSDINFDVLTVEENLsILASIK--GIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAV 629
Cdd:PRK11124 78 RELRRNVGMVFQQYNLWPHLTVQQNL-IEAPCRvlGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARAL 156
|
170
....*....|....*...
gi 146134400 630 LGNPKILLLDEPTAGMDP 647
Cdd:PRK11124 157 MMEPQVLLFDEPTAALDP 174
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
1313-1517 |
1.92e-19 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 90.49 E-value: 1.92e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1313 KVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG--DYGSHSSEDDESIKCMGYCPQtnplWPDLT 1390
Cdd:PRK13637 20 KKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDgvDITDKKVKLSDIRKKVGLVFQ----YPEYQ 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1391 LqehFE-------IYGAVK-GMSPGDMKEVISRITKA--LDLKEHLQKTVKKLPAGIKRKLCFA--LSMlgNPQVTLLDE 1458
Cdd:PRK13637 96 L---FEetiekdiAFGPINlGLSEEEIENRVKRAMNIvgLDYEDYKDKSPFELSGGQKRRVAIAgvVAM--EPKILILDE 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 1459 PSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTV 1517
Cdd:PRK13637 171 PTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTP 229
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
496-691 |
1.97e-19 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 90.19 E-value: 1.97e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 496 ALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRV---SEIDEMFEARKMIGIC---PQSDInfd 569
Cdd:PRK13649 22 ALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLItstSKNKDIKQIRKKVGLVfqfPESQL--- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 570 vltVEEnlSILASIKGIPANNIIQEVQKVLL---DLDMQAIKDNQAKK----LSGGQKRKLSVGIAVLGNPKILLLDEPT 642
Cdd:PRK13649 99 ---FEE--TVLKDVAFGPQNFGVSQEEAEALareKLALVGISESLFEKnpfeLSGGQMRRVAIAGILAMEPKILVLDEPT 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 146134400 643 AGMDPCSRHIVWNLLKYRKANRVT-VFSTHFMDEADILADRKAVISQGML 691
Cdd:PRK13649 174 AGLDPKGRKELMTLFKKLHQSGMTiVLVTHLMDDVANYADFVYVLEKGKL 223
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
492-696 |
2.32e-19 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 94.08 E-value: 2.32e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 492 ENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDeMFEARKMIGICPQSDINFDvL 571
Cdd:COG1132 351 GDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLT-LESLRRQIGVVPQDTFLFS-G 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 572 TVEENLSIlasikGIP-ANNiiQEVqkvlldldMQAIKDNQAK-------------------KLSGGQKRKLSvgIA--V 629
Cdd:COG1132 429 TIRENIRY-----GRPdATD--EEV--------EEAAKAAQAHefiealpdgydtvvgergvNLSGGQRQRIA--IAraL 491
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146134400 630 LGNPKILLLDEPTAGMDPCS-RHIVWNLLKYRKaNRVTVFSTH----FMDeadilADRKAVISQGMLKCVGS 696
Cdd:COG1132 492 LKDPPILILDEATSALDTETeALIQEALERLMK-GRTTIVIAHrlstIRN-----ADRILVLDDGRIVEQGT 557
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
1290-1510 |
2.89e-19 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 88.78 E-value: 2.89e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKKDFLHSrkttkvatkyISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSED 1369
Cdd:cd03256 1 IEVENLSKTYPNGKKALKD----------VSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKG 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 DE---SIKCMGYCPQTNPLWPDLT---------LQEHFEIYGAVKGMSPGDmKEVISRITKALDLKEHLQKTVKKLPAGI 1437
Cdd:cd03256 71 KAlrqLRRQIGMIFQQFNLIERLSvlenvlsgrLGRRSTWRSLFGLFPKEE-KQRALAALERVGLLDKAYQRADQLSGGQ 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1438 KRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQ 1510
Cdd:cd03256 150 QQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGR 222
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
484-689 |
3.04e-19 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 88.36 E-value: 3.04e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 484 QKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGhRVSEIDEMfearkMIGICPQ 563
Cdd:cd03220 25 ILGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRG-RVSSLLGL-----GGGFNPE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 564 sdinfdvLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTA 643
Cdd:cd03220 99 -------LTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLA 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 146134400 644 GMDPCSRHIVWNLLKYRKANRVTV-FSTHFMDEADILADRKAVISQG 689
Cdd:cd03220 172 VGDAAFQEKCQRRLRELLKQGKTViLVSHDPSSIKRLCDRALVLEKG 218
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
478-691 |
3.54e-19 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 88.01 E-value: 3.54e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYrkkTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEID--EMFEAR 555
Cdd:PRK10908 2 IRFEHVSKAY---LGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKnrEVPFLR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 556 KMIGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKI 635
Cdd:PRK10908 79 RQIGMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAV 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 636 LLLDEPTAGMDPCSRHIVWNLlkYRKANRVTV---FSTHFMDEADILADRKAVISQGML 691
Cdd:PRK10908 159 LLADEPTGNLDDALSEGILRL--FEEFNRVGVtvlMATHDIGLISRRSYRMLTLSDGHL 215
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
478-689 |
4.21e-19 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 86.60 E-value: 4.21e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTENVeaLRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEmfEARKM 557
Cdd:cd03247 1 LSINNVSFSYPEQEQQV--LKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEK--ALSSL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVltveenlsilasikgipanniiqevqkvlldldmqAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:cd03247 77 ISVLNQRPYLFDT-----------------------------------TLRNNLGRRFSGGERQRLALARILLQDAPIVL 121
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTH------FMDEAdILADRKAVISQG 689
Cdd:cd03247 122 LDEPTVGLDPITERQLLSLIFEVLKDKTLIWITHhltgieHMDKI-LFLENGKIIMQG 178
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1319-1516 |
4.56e-19 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 92.77 E-value: 4.56e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshsseDDESIKcmgycpQTNP-------------- 1384
Cdd:COG1129 23 VSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILL---------DGEPVR------FRSPrdaqaagiaiihqe 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1385 --LWPDLTLQE----HFEI--YGAVkgmspgDMKEVISRITKALD---LKEHLQKTVKKLPAGiKRKL---CFALSMlgN 1450
Cdd:COG1129 88 lnLVPNLSVAEniflGREPrrGGLI------DWRAMRRRARELLArlgLDIDPDTPVGDLSVA-QQQLveiARALSR--D 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 1451 PQVTLLDEPSTGMDPRAKQHMWRAIRTaFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLrcIGT 1516
Cdd:COG1129 159 ARVLILDEPTASLTEREVERLFRIIRR-LKAQGVAIIYISHRLDEVFEIADRVTVLRDGRL--VGT 221
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
496-696 |
4.64e-19 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 89.41 E-value: 4.64e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 496 ALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDG---FASIYGHRVSEIDEMFEARKMIGIC---PQSDInfd 569
Cdd:PRK13643 21 ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGkvtVGDIVVSSTSKQKEIKPVRKKVGVVfqfPESQL--- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 570 vltVEEnlSILASIKGIPANNII--QEVQKVLLD-LDMQAIKDNQAKK----LSGGQKRKLSVGIAVLGNPKILLLDEPT 642
Cdd:PRK13643 98 ---FEE--TVLKDVAFGPQNFGIpkEKAEKIAAEkLEMVGLADEFWEKspfeLSGGQMRRVAIAGILAMEPEVLVLDEPT 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 643 AGMDPCSRHIVWNLLK-YRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGS 696
Cdd:PRK13643 173 AGLDPKARIEMMQLFEsIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGT 227
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
1319-1510 |
5.34e-19 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 88.22 E-value: 5.34e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSG---KIFLGDYGShsseddESI----KCMGYcpqTNPlwpdlTL 1391
Cdd:COG1119 22 ISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGndvRLFGERRGG------EDVwelrKRIGL---VSP-----AL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1392 QEHFEIYGAVKGM-------SPG-------DMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLD 1457
Cdd:COG1119 88 QLRFPRDETVLDVvlsgffdSIGlyreptdEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIARALVKDPELLILD 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1458 EPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQ 1510
Cdd:COG1119 168 EPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGR 220
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
1294-1520 |
5.37e-19 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 87.62 E-value: 5.37e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYDDKKdflhsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTL-----VGDVEPTSGKIFL-GDYGSHSS 1367
Cdd:cd03260 5 DLNVYYGDKH-----------ALKDISLDIPKGEITALIGPSGCGKSTLLRLLnrlndLIPGAPDEGEVLLdGKDIYDLD 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1368 EDDESIKC-MGYCPQT-NPLwpDLTLQEHFEiYGA-VKGMSPgdMKEVISRITKALDlKEHLQKTVK------KLPAGIK 1438
Cdd:cd03260 74 VDVLELRRrVGMVFQKpNPF--PGSIYDNVA-YGLrLHGIKL--KEELDERVEEALR-KAALWDEVKdrlhalGLSGGQQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1439 RKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAfkNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQ 1518
Cdd:cd03260 148 QRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAEL--KKEYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTE 225
|
..
gi 146134400 1519 HL 1520
Cdd:cd03260 226 QI 227
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
478-695 |
1.14e-18 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 89.70 E-value: 1.14e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEmfeARKM 557
Cdd:PRK11000 4 VTLRNVTKAY----GDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPP---AERG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:PRK11000 77 VGMVFQSYALYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 638 LDEPTAGMDPCSR---HIVWNLLkYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVG 695
Cdd:PRK11000 157 LDEPLSNLDAALRvqmRIEISRL-HKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVG 216
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
1319-1516 |
1.39e-18 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 86.87 E-value: 1.39e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshsseDDESI----------KCMGYCPQTNPLWPD 1388
Cdd:PRK10895 22 VSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIII---------DDEDIsllplhararRGIGYLPQEASIFRR 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1389 LTLQEHFeiygavkgMSPGDMKEVIS---RITKALDLKE-----HLQKTV-KKLPAGIKRKLCFALSMLGNPQVTLLDEP 1459
Cdd:PRK10895 93 LSVYDNL--------MAVLQIRDDLSaeqREDRANELMEefhieHLRDSMgQSLSGGERRRVEIARALAANPKFILLDEP 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 1460 STGMDPRAKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGT 1516
Cdd:PRK10895 165 FAGVDPISVIDIKRIIE-HLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGT 220
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1285-1517 |
1.52e-18 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 90.86 E-value: 1.52e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1285 EEKPAIMVCNLHKEYDDKkdflhsrkttkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGS 1364
Cdd:COG3845 1 MMPPALELRGITKRFGGV-----------VANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPV 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1365 HSSEDDESIKC-MGYCPQTNPLWPDLTLQEHFeIYGAVKGMSPG-DMKEVISRIT---KALDLKEHLQKTVKKLPAGIKR 1439
Cdd:COG3845 70 RIRSPRDAIALgIGMVHQHFMLVPNLTVAENI-VLGLEPTKGGRlDRKAARARIRelsERYGLDVDPDAKVEDLSVGEQQ 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1440 KL----CfalsMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLrcIG 1515
Cdd:COG3845 149 RVeilkA----LYRGARILILDEPTAVLTPQEADELFEILR-RLAAEGKSIIFITHKLREVMAIADRVTVLRRGKV--VG 221
|
..
gi 146134400 1516 TV 1517
Cdd:COG3845 222 TV 223
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
476-696 |
1.55e-18 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 86.67 E-value: 1.55e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 476 EAIRISGIQKSYR------------------KKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGF 537
Cdd:COG1134 3 SMIEVENVSKSYRlyhepsrslkelllrrrrTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 538 ASIYGhRVSEIDEMfearkMIGICPQsdinfdvLTVEENLSILASIKGIPAnniiQEVQKVlldldMQAIK--------- 608
Cdd:COG1134 83 VEVNG-RVSALLEL-----GAGFHPE-------LTGRENIYLNGRLLGLSR----KEIDEK-----FDEIVefaelgdfi 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 609 DNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDP-----CSRHIvwnlLKYRKANRVTVFSTHFMDEADILADRK 683
Cdd:COG1134 141 DQPVKTYSSGMRARLAFAVATAVDPDILLVDEVLAVGDAafqkkCLARI----RELRESGRTVIFVSHSMGAVRRLCDRA 216
|
250
....*....|...
gi 146134400 684 AVISQGMLKCVGS 696
Cdd:COG1134 217 IWLEKGRLVMDGD 229
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
1288-1515 |
1.62e-18 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 89.51 E-value: 1.62e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1288 PAIMVCNLHKEYDDKKdflhsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFL-GDYGSHS 1366
Cdd:PRK11607 18 PLLEIRNLTKSFDGQH-----------AVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLdGVDLSHV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1367 SEDDESIKCMGycpQTNPLWPDLTLQEHFEiYGAVKGMSPGDmkEVISRITKALDLKeHLQKTVKKLP----AGIKRKLC 1442
Cdd:PRK11607 87 PPYQRPINMMF---QSYALFPHMTVEQNIA-FGLKQDKLPKA--EIASRVNEMLGLV-HMQEFAKRKPhqlsGGQRQRVA 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1443 FALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIG 1515
Cdd:PRK11607 160 LARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIG 232
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
473-695 |
1.68e-18 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 91.02 E-value: 1.68e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 473 IGKEAIRISGIQKSYRKKTENV-EALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIyghRVSE---- 547
Cdd:TIGR03269 275 VGEPIIKVRNVSKRYISVDRGVvKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNV---RVGDewvd 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 548 -----IDEMFEARKMIGICPQSDINFDVLTVEENLSILASIKgIPANniiQEVQKVLLDLDMQAIKDNQAK--------K 614
Cdd:TIGR03269 352 mtkpgPDGRGRAKRYIGILHQEYDLYPHRTVLDNLTEAIGLE-LPDE---LARMKAVITLKMVGFDEEKAEeildkypdE 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 615 LSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWN-LLKYRKA-NRVTVFSTHFMDEADILADRKAVISQGMLK 692
Cdd:TIGR03269 428 LSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHsILKAREEmEQTFIIVSHDMDFVLDVCDRAALMRDGKIV 507
|
...
gi 146134400 693 CVG 695
Cdd:TIGR03269 508 KIG 510
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
495-671 |
1.68e-18 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 91.27 E-value: 1.68e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 495 EALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMfEARKMIGICPQSDINFDVlTVE 574
Cdd:TIGR02868 349 PVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQD-EVRRRVSVCAQDAHLFDT-TVR 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 575 ENLSILAsiKGIPANNIIQEVQKVLLDLDMQAIKDN-------QAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDP 647
Cdd:TIGR02868 427 ENLRLAR--PDATDEELWAALERVGLADWLRALPDGldtvlgeGGARLSGGERQRLALARALLADAPILLLDEPTEHLDA 504
|
170 180
....*....|....*....|....
gi 146134400 648 CSRHIVWNLLKYRKANRVTVFSTH 671
Cdd:TIGR02868 505 ETADELLEDLLAALSGRTVVLITH 528
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
500-745 |
1.81e-18 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 89.02 E-value: 1.81e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 500 LSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSE----IDEMFEARKmIGICPQSDINFDVLTVEE 575
Cdd:TIGR02142 16 ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDsrkgIFLPPEKRR-IGYVFQEARLFPHLSVRG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 576 NLSILASIKGIPANNIIQEvqKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMD-PCSRHIVW 654
Cdd:TIGR02142 95 NLRYGMKRARPSERRISFE--RVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDdPRKYEILP 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 655 NLLKYRKANRV-TVFSTHFMDEADILADRKAVISQGMLKCVGSsifLKSKWGigyRLSM-YIDRYCATESLSSLVRQHIP 732
Cdd:TIGR02142 173 YLERLHAEFGIpILYVSHSLQEVLRLADRVVVLEDGRVAAAGP---IAEVWA---SPDLpWLAREDQGSLIEGVVAEHDQ 246
|
250
....*....|....*
gi 146134400 733 AAAL--LQQNDQQLV 745
Cdd:TIGR02142 247 HYGLtaLRLGGGHLW 261
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
1289-1516 |
3.55e-18 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 85.47 E-value: 3.55e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1289 AIMVCNLHKEYDDkkdFlhsrkttkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG--DYGSHS 1366
Cdd:cd03296 2 SIEVRNVSKRFGD---F--------VALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGgeDATDVP 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1367 SEDDEsikcMGYCPQTNPLWPDLTLQEH----FEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLC 1442
Cdd:cd03296 71 VQERN----VGFVFQHYALFRHMTVFDNvafgLRVKPRSERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVA 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 146134400 1443 FALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGT 1516
Cdd:cd03296 147 LARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGT 220
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
1319-1491 |
3.72e-18 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 84.54 E-value: 3.72e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYcpqTNPLWPDLTLQEHFEIY 1398
Cdd:PRK13539 21 LSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEACHYLGH---RNAMKPALTVAENLEFW 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1399 GAVKGMSPGDMKEVISRItkALDLKEHLQktVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDpRAKQHMWRAIRTA 1478
Cdd:PRK13539 98 AAFLGGEELDIAAALEAV--GLAPLAHLP--FGYLSAGQKRRVALARLLVSNRPIWILDEPTAALD-AAAVALFAELIRA 172
|
170
....*....|...
gi 146134400 1479 FKNKKRAALLTTH 1491
Cdd:PRK13539 173 HLAQGGIVIAATH 185
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
496-696 |
3.72e-18 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 88.94 E-value: 3.72e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 496 ALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEID--EMFEAR-KMIGICPQSDINFDVLT 572
Cdd:PRK10070 43 GVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISdaELREVRrKKIAMVFQSFALMPHMT 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 573 VEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHI 652
Cdd:PRK10070 123 VLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTE 202
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 146134400 653 VWN-LLKYR-KANRVTVFSTHFMDEADILADRKAVISQGMLKCVGS 696
Cdd:PRK10070 203 MQDeLVKLQaKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGT 248
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
477-691 |
4.68e-18 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 85.86 E-value: 4.68e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKtenvEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGF----------ASIYGHRVS 546
Cdd:COG1117 11 KIEVRNLNVYYGDK----QALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNDLIPGArvegeilldgEDIYDPDVD 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 547 EIdemfEARKMIGICPQSDINFdVLTVEENLSILASIKGIPANNIIQE-VQKVLLdldmQA-----IKDN---QAKKLSG 617
Cdd:COG1117 87 VV----ELRRRVGMVFQKPNPF-PKSIYDNVAYGLRLHGIKSKSELDEiVEESLR----KAalwdeVKDRlkkSALGLSG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 618 GQKRKLSV--GIAVlgNPKILLLDEPTAGMDPCSRHIVWNL---LKyrkaNRVT-VFSTHFMDEADILADRKAVISQGML 691
Cdd:COG1117 158 GQQQRLCIarALAV--EPEVLLMDEPTSALDPISTAKIEELileLK----KDYTiVIVTHNMQQAARVSDYTAFFYLGEL 231
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
1319-1530 |
6.12e-18 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 89.89 E-value: 6.12e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYgshsseDDESI------KCMGYCPQTNPLWPDlTLQ 1392
Cdd:COG2274 494 ISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGI------DLRQIdpaslrRQIGVVLQDVFLFSG-TIR 566
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1393 EHfeIYGAVKGMSPGDMKEVIsRITKALDLKEHLQK---TV-----KKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMD 1464
Cdd:COG2274 567 EN--ITLGDPDATDEEIIEAA-RLAGLHDFIEALPMgydTVvgeggSNLSGGQRQRLAIARALLRNPRILILDEATSALD 643
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 1465 PRAKQHMWRAIRTAFKNkkRAALLTTHYMEEAEAvCDRVAIMVSGQLRCIGTVQHLKSKFGKGYFL 1530
Cdd:COG2274 644 AETEAIILENLRRLLKG--RTVIIIAHRLSTIRL-ADRIIVLDKGRIVEDGTHEELLARKGLYAEL 706
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
491-701 |
8.08e-18 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 85.62 E-value: 8.08e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 491 TENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEiDEMFEARKMIGICPQ-SDINFD 569
Cdd:PRK13652 14 SGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITK-ENIREVRKFVGLVFQnPDDQIF 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 570 VLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCS 649
Cdd:PRK13652 93 SPTVEQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQG 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 650 RHivwNLLKYRKANRVT-----VFSTHFMDEADILADRKAVISQGMLKCVGS--SIFLK 701
Cdd:PRK13652 173 VK---ELIDFLNDLPETygmtvIFSTHQLDLVPEMADYIYVMDKGRIVAYGTveEIFLQ 228
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
483-646 |
9.58e-18 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 83.47 E-value: 9.58e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 483 IQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLcppSDGFASIYGHrVS----EIDEMFE-ARKM 557
Cdd:cd03233 9 ISFTTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANR---TEGNVSVEGD-IHyngiPYKEFAEkYPGE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVLTVEENLSILASIKGipaNNIIqevqkvlldldmqaikdnqaKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:cd03233 85 IIYVSEEDVHFPTLTVRETLDFALRCKG---NEFV--------------------RGISGGERKRVSIAEALVSRASVLC 141
|
....*....
gi 146134400 638 LDEPTAGMD 646
Cdd:cd03233 142 WDNSTRGLD 150
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
501-696 |
1.14e-17 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 86.69 E-value: 1.14e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 501 SFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGH----RVSEIDEMFEARKmIGICPQSDINFDVLTVEEN 576
Cdd:COG4148 19 DFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEvlqdSARGIFLPPHRRR-IGYVFQEARLFPHLSVRGN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 577 LsiLASIKGIPANNiiqevQKVLLD-----LDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRH 651
Cdd:COG4148 98 L--LYGRKRAPRAE-----RRISFDevvelLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKA 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 146134400 652 ivwNLLKY-----RKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGS 696
Cdd:COG4148 171 ---EILPYlerlrDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGP 217
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
476-696 |
1.29e-17 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 84.44 E-value: 1.29e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 476 EAIRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEID--EMfe 553
Cdd:PRK13548 1 AMLEARNLSVRLGGRT----LLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSpaEL-- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 554 ARkMIGICPQ-SDINFDvLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGG-QKRklsVGIA-VL 630
Cdd:PRK13548 75 AR-RRAVLPQhSSLSFP-FTVEEVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGeQQR---VQLArVL 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 631 -------GNPKILLLDEPTAGMDPCSRHIVWNLLKYR-KANRVTVFST-HFMDEADILADRKAVISQGMLKCVGS 696
Cdd:PRK13548 150 aqlwepdGPPRWLLLDEPTSALDLAHQHHVLRLARQLaHERGLAVIVVlHDLNLAARYADRIVLLHQGRLVADGT 224
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
496-689 |
1.57e-17 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 82.09 E-value: 1.57e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 496 ALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRV--SEIDEMFEA--------RKMIGICPQsd 565
Cdd:cd03215 15 AVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVtrRSPRDAIRAgiayvpedRKREGLVLD-- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 566 infdvLTVEENLSILASikgipanniiqevqkvlldldmqaikdnqakkLSGGQKRKLSVGIAVLGNPKILLLDEPTAGM 645
Cdd:cd03215 93 -----LSVAENIALSSL--------------------------------LSGGNQQKVVLARWLARDPRVLILDEPTRGV 135
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 146134400 646 DPCSRHIVWNLL-KYRKANR-VTVFSTHfMDEADILADRKAVISQG 689
Cdd:cd03215 136 DVGAKAEIYRLIrELADAGKaVLLISSE-LDELLGLCDRILVMYEG 180
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
474-642 |
1.58e-17 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 87.81 E-value: 1.58e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 474 GKEAIRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfaSI-YGHRVSeidemf 552
Cdd:COG0488 312 GKKVLELEGLSKSY----GDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSG--TVkLGETVK------ 379
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 553 earkmIGICPQSDINFDvltveENLSILASIKGIPANNIIQEVQKVLLDL----DMQaikDNQAKKLSGGQKRKLSVGIA 628
Cdd:COG0488 380 -----IGYFDQHQEELD-----PDKTVLDELRDGAPGGTEQEVRGYLGRFlfsgDDA---FKPVGVLSGGEKARLALAKL 446
|
170
....*....|....
gi 146134400 629 VLGNPKILLLDEPT 642
Cdd:COG0488 447 LLSPPNVLLLDEPT 460
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
1287-1566 |
1.72e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 84.27 E-value: 1.72e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1287 KPAIMVCNLHKEYDDKKdflhsrkttKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHS 1366
Cdd:PRK13632 5 SVMIKVENVSFSYPNSE---------NNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1367 SEDDESIKCMGYCPQTnplwPD-----LTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKL 1441
Cdd:PRK13632 76 ENLKEIRKKIGIIFQN----PDnqfigATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRV 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1442 CFALSMLGNPQVTLLDEpSTGM-DPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAeAVCDRVAIMVSGQLRCIGTVQHL 1520
Cdd:PRK13632 152 AIASVLALNPEIIIFDE-STSMlDPKGKREIKKIMVDLRKTRKKTLISITHDMDEA-ILADKVIVFSEGKLIAQGKPKEI 229
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 146134400 1521 kskfgkgyfleIKLKDWIENLEID-----RLQREIQYIFPNASRQESFSSI 1566
Cdd:PRK13632 230 -----------LNNKEILEKAKIDspfiyKLSKKLKGIDPTYNEEELIEQI 269
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
484-684 |
2.00e-17 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 84.06 E-value: 2.00e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 484 QKSYRKKTENVE-------ALRNLSFDIYEGQITALLGHSGTGKSTLM---NILCGLCPP--SDGFASIYGHRV--SEID 549
Cdd:PRK14243 6 GTETVLRTENLNvyygsflAVKNVWLDIPKNQITAFIGPSGCGKSTILrcfNRLNDLIPGfrVEGKVTFHGKNLyaPDVD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 550 EMfEARKMIGICPQSDINFDVlTVEENLSILASIKGIPANniIQEV------QKVLLDLDMQAIKDNqAKKLSGGQKRKL 623
Cdd:PRK14243 86 PV-EVRRRIGMVFQKPNPFPK-SIYDNIAYGARINGYKGD--MDELverslrQAALWDEVKDKLKQS-GLSLSGGQQQRL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 624 SVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKA 684
Cdd:PRK14243 161 CIARAIAVQPEVILMDEPCSALDPISTLRIEELMHELKEQYTIIIVTHNMQQAARVSDMTA 221
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
486-691 |
2.03e-17 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 83.29 E-value: 2.03e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 486 SYRKKTEnVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARK--MIGICP- 562
Cdd:cd03248 20 AYPTRPD-TLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKYLHSKvsLVGQEPv 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 563 ------QSDINFDVLTVEENlSILASIKGIPANNIIQEVQKvlldlDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKIL 636
Cdd:cd03248 99 lfarslQDNIAYGLQSCSFE-CVKEAAQKAHAHSFISELAS-----GYDTEVGEKGSQLSGGQKQRVAIARALIRNPQVL 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 637 LLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADiLADRKAVISQGML 691
Cdd:cd03248 173 ILDEATSALDAESEQQVQQALYDWPERRTVLVIAHRLSTVE-RADQILVLDGGRI 226
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
477-682 |
3.15e-17 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 82.87 E-value: 3.15e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEmfEAR- 555
Cdd:COG4181 8 IIELRGLTKTVGTGAGELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDE--DARa 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 556 ----KMIGICPQSdinF---DVLTVEENlsilasikgipanniiqevqkVLLDLDMQAIKDNQA---------------- 612
Cdd:COG4181 86 rlraRHVGFVFQS---FqllPTLTALEN---------------------VMLPLELAGRRDARArarallervglghrld 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 613 ---KKLSGG-QKRklsVGIA--VLGNPKILLLDEPTAGMDPCSRHIVWNLL-KYRKANRVT-VFSTHfmDEAdiLADR 682
Cdd:COG4181 142 hypAQLSGGeQQR---VALAraFATEPAILFADEPTGNLDAATGEQIIDLLfELNRERGTTlVLVTH--DPA--LAAR 212
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
490-658 |
3.91e-17 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 81.14 E-value: 3.91e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 490 KTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGlcppsdgfASIYGHRVSEI-------DEMFeaRKMIGICP 562
Cdd:cd03232 16 KGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAG--------RKTAGVITGEIlingrplDKNF--QRSTGYVE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 563 QSDINFDVLTVEENLSILASIKGipanniiqevqkvlldldmqaikdnqakkLSGGQKRKLSVGIAVLGNPKILLLDEPT 642
Cdd:cd03232 86 QQDVHSPNLTVREALRFSALLRG-----------------------------LSVEQRKRLTIGVELAAKPSILFLDEPT 136
|
170
....*....|....*.
gi 146134400 643 AGMDPCSRHIVWNLLK 658
Cdd:cd03232 137 SGLDSQAAYNIVRFLK 152
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
1315-1544 |
4.16e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 83.74 E-value: 4.16e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1315 ATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG----DYGSHSSEDDESIKCMGYCPQTNPLWPDLT 1390
Cdd:PRK13636 21 ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDgkpiDYSRKGLMKLRESVGMVFQDPDNQLFSASV 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1391 LQEhfEIYGAVKGMSPGDmkEVISRITKALDLK--EHLQ-KTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRA 1467
Cdd:PRK13636 101 YQD--VSFGAVNLKLPED--EVRKRVDNALKRTgiEHLKdKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMG 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1468 KQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLkskFGK--------------GYFLEI- 1532
Cdd:PRK13636 177 VSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEV---FAEkemlrkvnlrlpriGHLMEIl 253
|
250
....*....|..
gi 146134400 1533 KLKDWIENLEID 1544
Cdd:PRK13636 254 KEKDGFVFDELD 265
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
1290-1511 |
4.20e-17 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 81.81 E-value: 4.20e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKKdflhsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGD--YGSHSS 1367
Cdd:cd03262 1 IEIKNLHKSFGDFH-----------VLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGlkLTDDKK 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1368 EDDESIKCMGYCPQTNPLWPDLTLQEHfeIYGA---VKGMSPgdmKEVISRITKALD---LKEHLQKTVKKLPAGIKRKL 1441
Cdd:cd03262 70 NINELRQKVGMVFQQFNLFPHLTVLEN--ITLApikVKGMSK---AEAEERALELLEkvgLADKADAYPAQLSGGQQQRV 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1442 CFALSMLGNPQVTLLDEPSTGMDPR------------AKQHMwrairtafknkkrAALLTTHYMEEAEAVCDRVAIMVSG 1509
Cdd:cd03262 145 AIARALAMNPKVMLFDEPTSALDPElvgevldvmkdlAEEGM-------------TMVVVTHEMGFAREVADRVIFMDDG 211
|
..
gi 146134400 1510 QL 1511
Cdd:cd03262 212 RI 213
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
478-685 |
4.65e-17 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 83.95 E-value: 4.65e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPP---SDGFASIYGHRVSEID--EMF 552
Cdd:COG0444 2 LEVRNLKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGEDLLKLSekELR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 553 EAR-KMIGICPQSDIN-FD-VLTVEENLS-ILASIKGIPANNIIQEVQKVL----LDLDMQAIKD--NQakkLSGGQKRK 622
Cdd:COG0444 82 KIRgREIQMIFQDPMTsLNpVMTVGDQIAePLRIHGGLSKAEARERAIELLervgLPDPERRLDRypHE---LSGGMRQR 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 623 LSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVT--VFSTHfmdeaDI-----LADRKAV 685
Cdd:COG0444 159 VMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLaiLFITH-----DLgvvaeIADRVAV 223
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
477-677 |
4.98e-17 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 87.49 E-value: 4.98e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKktenVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHrvseidEMFEARK 556
Cdd:NF033858 1 VARLEGVSHRYGK----TVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGG------DMADARH 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQsdINF----------DVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVG 626
Cdd:NF033858 71 RRAVCPR--IAYmpqglgknlyPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLC 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 627 IAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANR----VTVfSTHFMDEAD 677
Cdd:NF033858 149 CALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAERpgmsVLV-ATAYMEEAE 202
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
497-695 |
7.87e-17 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 85.86 E-value: 7.87e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEID-EMFEarKMIGICPQsDINFDVLTVEE 575
Cdd:TIGR01842 334 LRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDrETFG--KHIGYLPQ-DVELFPGTVAE 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 576 NLS----ILASIKGIPANNIIQeVQKVLLDLDM---QAIKDNQAKkLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPC 648
Cdd:TIGR01842 411 NIArfgeNADPEKIIEAAKLAG-VHELILRLPDgydTVIGPGGAT-LSGGQRQRIALARALYGDPKLVVLDEPNSNLDEE 488
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 146134400 649 SRHIVWNLLKYRKANRVTV-FSTHfMDEADILADRKAVISQGMLKCVG 695
Cdd:TIGR01842 489 GEQALANAIKALKARGITVvVITH-RPSLLGCVDKILVLQDGRIARFG 535
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1319-1511 |
8.12e-17 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 85.46 E-value: 8.12e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGD--YGSHSSEDdeSIKC-MGYCP---QTNPLWPDLTLQ 1392
Cdd:COG1129 271 VSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGkpVRIRSPRD--AIRAgIAYVPedrKGEGLVLDLSIR 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1393 E-----HFEIYGAVKGMSPGDMKEVISRITKALDLK-EHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPR 1466
Cdd:COG1129 349 EnitlaSLDRLSRGGLLDRRRERALAEEYIKRLRIKtPSPEQPVGNLSGGNQQKVVLAKWLATDPKVLILDEPTRGIDVG 428
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 146134400 1467 AKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:COG1129 429 AKAEIYRLIR-ELAAEGKAVIVISSELPELLGLSDRILVMREGRI 472
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
495-647 |
1.01e-16 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 80.48 E-value: 1.01e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 495 EALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFeARKMIGICPQSDINfDVLTVE 574
Cdd:TIGR01189 14 MLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDEP-HENILYLGHLPGLK-PELSAL 91
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 575 ENLSILASIKGIPANNIIQEVQKVLLDldmqAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDP 647
Cdd:TIGR01189 92 ENLHFWAAIHGGAQRTIEDALAAVGLT----GFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDK 160
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
493-697 |
1.03e-16 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 81.50 E-value: 1.03e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 493 NVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLC-----PPSDGFASIYGHRVSEIDeMFEARKMIGICPQSDIN 567
Cdd:PRK14247 15 QVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIelypeARVSGEVYLDGQDIFKMD-VIELRRRVQMVFQIPNP 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 568 FDVLTVEENLSI------LASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEP 641
Cdd:PRK14247 94 IPNLSIFENVALglklnrLVKSKKELQERVRWALEKAQLWDEVKDRLDAPAGKLSGGQQQRLCIARALAFQPEVLLADEP 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 642 TAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSS 697
Cdd:PRK14247 174 TANLDPENTAKIESLFLELKKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPT 229
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
461-689 |
1.35e-16 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 85.26 E-value: 1.35e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 461 LNEIVE-PVSSEFIGKE-------AIRISGIQKSYRKKTENVeaLRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCP 532
Cdd:PRK11160 314 INEITEqKPEVTFPTTStaaadqvSLTLNNVSFTYPDQPQPV--LKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWD 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 533 PSDGFASIYGHRVSEIDEMfEARKMIGICPQSdinFDVL--TVEENLSILASikgiPANN--IIQEVQKVLLDLDMQAIK 608
Cdd:PRK11160 392 PQQGEILLNGQPIADYSEA-ALRQAISVVSQR---VHLFsaTLRDNLLLAAP----NASDeaLIEVLQQVGLEKLLEDDK 463
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 609 DNQA------KKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDP-CSRHIVWNLLKYRKaNRVTVFSTH---FMDEAD- 677
Cdd:PRK11160 464 GLNAwlgeggRQLSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAeTERQILELLAEHAQ-NKTVLMITHrltGLEQFDr 542
|
250
....*....|...
gi 146134400 678 -ILADRKAVISQG 689
Cdd:PRK11160 543 iCVMDNGQIIEQG 555
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
1319-1506 |
1.56e-16 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 85.03 E-value: 1.56e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQTnPLWPDLTLQEhfEIY 1398
Cdd:TIGR02857 341 VSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWRDQIAWVPQH-PFLFAGTIAE--NIR 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1399 GAVKGMSPGDMKEVISRiTKALDLkehlqktVKKLPAGI---------------KRKLCFALSMLGNPQVTLLDEPSTGM 1463
Cdd:TIGR02857 418 LARPDASDAEIREALER-AGLDEF-------VAALPQGLdtpigeggaglsggqAQRLALARAFLRDAPLLLLDEPTAHL 489
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 146134400 1464 DPRAKQHMWRAIRTAFKNkkRAALLTTHYMEEAEAvCDRVAIM 1506
Cdd:TIGR02857 490 DAETEAEVLEALRALAQG--RTVLLVTHRLALAAL-ADRIVVL 529
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
478-696 |
1.80e-16 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 81.98 E-value: 1.80e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTE-NVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfASIYGH-----RVSEIDEM 551
Cdd:PRK13645 7 IILDNVSYTYAKKTPfEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETG-QTIVGDyaipaNLKKIKEV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 552 FEARKMIGIC---PQSDINFDvlTVEENLSILASIKGIPANNIIQEVQKVLldlDMQAIKDNQAKK----LSGGQKRKLS 624
Cdd:PRK13645 86 KRLRKEIGLVfqfPEYQLFQE--TIEKDIAFGPVNLGENKQEAYKKVPELL---KLVQLPEDYVKRspfeLSGGQKRRVA 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 625 VGIAVLGNPKILLLDEPTAGMDPCSRHIVWNL---LKYRKANRVtVFSTHFMDEADILADRKAVISQGMLKCVGS 696
Cdd:PRK13645 161 LAGIIAMDGNTLVLDEPTGGLDPKGEEDFINLferLNKEYKKRI-IMVTHNMDQVLRIADEVIVMHEGKVISIGS 234
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
1319-1511 |
1.96e-16 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 80.39 E-value: 1.96e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEptSGKIFLGD--YGSHSSEDDESIKCMGYCPQTNPLWPDLTLQEHfe 1396
Cdd:cd03234 26 VSLHVESGQVMAILGSSGSGKTTLLDAISGRVE--GGGTTSGQilFNGQPRKPDQFQKCVAYVRQDDILLPGLTVRET-- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1397 IYGAVKGMSPGDMKEVISRITKALDLKEHLQKT------VKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQH 1470
Cdd:cd03234 102 LTYTAILRLPRKSSDAIRKKRVEDVLLRDLALTriggnlVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSFTALN 181
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 146134400 1471 MWRAIR-TAFKNkkRAALLTTHY-MEEAEAVCDRVAIMVSGQL 1511
Cdd:cd03234 182 LVSTLSqLARRN--RIVILTIHQpRSDLFRLFDRILLLSSGEI 222
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
1311-1511 |
2.32e-16 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 78.63 E-value: 2.32e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1311 TTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKC-MGYCP---QTNPLW 1386
Cdd:cd03215 11 SVKGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDAIRAgIAYVPedrKREGLV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1387 PDLTLQEHFeiygavkgmspgdmkeVISRItkaldlkehlqktvkkLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPR 1466
Cdd:cd03215 91 LDLSVAENI----------------ALSSL----------------LSGGNQQKVVLARWLARDPRVLILDEPTRGVDVG 138
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 146134400 1467 AKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:cd03215 139 AKAEIYRLIR-ELADAGKAVLLISSELDELLGLCDRILVMYEGRI 182
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
1286-1515 |
2.61e-16 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 84.08 E-value: 2.61e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1286 EKPAIMVCNLHKEYddkkdFLHSRKTTKvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIF--LGD-- 1361
Cdd:TIGR03269 276 GEPIIKVRNVSKRY-----ISVDRGVVK-AVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNvrVGDew 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1362 ---YGSHSSEDDESIKCMGYCPQTNPLWPDLTLQEHF-EIYGAVKGMSPGDMKEVISRITKALD---LKEHLQKTVKKLP 1434
Cdd:TIGR03269 350 vdmTKPGPDGRGRAKRYIGILHQEYDLYPHRTVLDNLtEAIGLELPDELARMKAVITLKMVGFDeekAEEILDKYPDELS 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1435 AGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCI 1514
Cdd:TIGR03269 430 EGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKI 509
|
.
gi 146134400 1515 G 1515
Cdd:TIGR03269 510 G 510
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1315-1566 |
2.79e-16 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 84.07 E-value: 2.79e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1315 ATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYG-SHSSEDDESIKCMGYCPQTNPLWPDLTLQE 1393
Cdd:PRK09700 20 ALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINyNKLDHKLAAQLGIGIIYQELSVIDELTVLE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1394 HFEI----YGAVKGMSPGD---MKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPR 1466
Cdd:PRK09700 100 NLYIgrhlTKKVCGVNIIDwreMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDAKVIIMDEPTSSLTNK 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1467 AKQHMWrAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHlkskfgkgyfleiklkdwIENLEIDRL 1546
Cdd:PRK09700 180 EVDYLF-LIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVSD------------------VSNDDIVRL 240
|
250 260
....*....|....*....|..
gi 146134400 1547 Q--REIQYIFPnaSRQESFSSI 1566
Cdd:PRK09700 241 MvgRELQNRFN--AMKENVSNL 260
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
486-691 |
2.86e-16 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 84.38 E-value: 2.86e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 486 SYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIdEMFEARKMIGICPQSD 565
Cdd:TIGR02203 337 TFRYPGRDRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADY-TLASLRRQVALVSQDV 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 566 INFDVlTVEENLSIlasikGIPANNIIQEVQKVLLDLDMQAIKDN-----------QAKKLSGGQKRKLSVGIAVLGNPK 634
Cdd:TIGR02203 416 VLFND-TIANNIAY-----GRTEQADRAEIERALAAAYAQDFVDKlplgldtpigeNGVLLSGGQRQRLAIARALLKDAP 489
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 635 ILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADiLADRKAVISQGML 691
Cdd:TIGR02203 490 ILILDEATSALDNESERLVQAALERLMQGRTTLVIAHRLSTIE-KADRIVVMDDGRI 545
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
1290-1524 |
3.97e-16 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 83.70 E-value: 3.97e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKKdflhsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVG--DVEPTSGKIFL-------- 1359
Cdd:TIGR03269 1 IEVKNLTKKFDGKE-----------VLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGmdQYEPTSGRIIYhvalcekc 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1360 GDYGSHSSEDDESIKCMG-YCPQTNPLW-PD------------LTLQEHFEIYG-------AVKGMS----PGDmkeviS 1414
Cdd:TIGR03269 70 GYVERPSKVGEPCPVCGGtLEPEEVDFWnLSdklrrrirkriaIMLQRTFALYGddtvldnVLEALEeigyEGK-----E 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1415 RITKALDLKEHLQ------KTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALL 1488
Cdd:TIGR03269 145 AVGRAVDLIEMVQlshritHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVL 224
|
250 260 270
....*....|....*....|....*....|....*.
gi 146134400 1489 TTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKF 1524
Cdd:TIGR03269 225 TSHWPEVIEDLSDKAIWLENGEIKEEGTPDEVVAVF 260
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
496-682 |
4.06e-16 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 78.43 E-value: 4.06e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 496 ALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRV-------SEIDEMFearkmigicPqsdinf 568
Cdd:NF040873 7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARvayvpqrSEVPDSL---------P------ 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 569 dvLTVEENLSI----LASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAG 644
Cdd:NF040873 72 --LTVRDLVAMgrwaRRGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTG 149
|
170 180 190
....*....|....*....|....*....|....*....
gi 146134400 645 MDPCSRHIVWNLLKYRKANRVTVF-STHFMDEAdILADR 682
Cdd:NF040873 150 LDAESRERIIALLAEEHARGATVVvVTHDLELV-RRADP 187
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
507-646 |
5.01e-16 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 79.05 E-value: 5.01e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 507 GQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEmfEAR-----KMIGICPQSDINFDVLTVEENLSILA 581
Cdd:PRK10584 36 GETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDE--EARaklraKHVGFVFQSFMLIPTLNALENVELPA 113
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 582 SIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMD 646
Cdd:PRK10584 114 LLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLD 178
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
1311-1516 |
5.27e-16 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 80.13 E-value: 5.27e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1311 TTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESI-KCMGYCPQTnplwPD- 1388
Cdd:PRK13633 21 TEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEENLWDIrNKAGMVFQN----PDn 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1389 ---LTLQEHFEIYGAVK-GMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFA--LSMlgNPQVTLLDEPSTG 1462
Cdd:PRK13633 97 qivATIVEEDVAFGPENlGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAgiLAM--RPECIIFDEPTAM 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 146134400 1463 MDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAeAVCDRVAIMVSGQLRCIGT 1516
Cdd:PRK13633 175 LDPSGRREVVNTIKELNKKYGITIILITHYMEEA-VEADRIIVMDSGKVVMEGT 227
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
487-689 |
5.29e-16 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 80.05 E-value: 5.29e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 487 YRKKTENVeaLRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDE-MFEARKMIGICPQ-- 563
Cdd:PRK13638 9 FRYQDEPV--LKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDYSKRgLLALRQQVATVFQdp 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 564 ------SDINFDVLTVEENLsilasikGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:PRK13638 87 eqqifyTDIDSDIAFSLRNL-------GVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLL 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLK--YRKANRVtVFSTHFMDEADILADRKAVISQG 689
Cdd:PRK13638 160 LDEPTAGLDPAGRTQMIAIIRriVAQGNHV-IISSHDIDLIYEISDAVYVLRQG 212
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
1323-1511 |
5.84e-16 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 78.30 E-value: 5.84e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1323 VKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYcpQTNPLWPDLTLQEHFEIygavk 1402
Cdd:cd03298 21 FAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPADRPVSMLF--QENNLFAHLTVEQNVGL----- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1403 GMSPG-----DMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRT 1477
Cdd:cd03298 94 GLSPGlkltaEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDLVLD 173
|
170 180 190
....*....|....*....|....*....|....
gi 146134400 1478 AFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:cd03298 174 LHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRI 207
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
1294-1520 |
6.10e-16 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 78.78 E-value: 6.10e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYDDKKDFLHsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG--DYGSHS-SEDD 1370
Cdd:cd03258 6 NVSKVFGDTGGKVT-------ALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDgtDLTLLSgKELR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1371 ESIKCMGYCPQTNPLWPDLTLQEH----FEIYGAvkgmspgDMKEVISRITKAL---DLKEHLQKTVKKLPAGIKRKLCF 1443
Cdd:cd03258 79 KARRRIGMIFQHFNLLSSRTVFENvalpLEIAGV-------PKAEIEERVLELLelvGLEDKADAYPAQLSGGQKQRVGI 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 1444 ALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAfkNKKR--AALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL 1520
Cdd:cd03258 152 ARALANNPKVLLCDEATSALDPETTQSILALLRDI--NRELglTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEV 228
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
458-710 |
6.63e-16 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 83.64 E-value: 6.63e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 458 NISLNEiVEPVSSEFIGKEA----------IRISGIQKSYrkkTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNIL 527
Cdd:TIGR01193 445 NNRLNE-VYLVDSEFINKKKrtelnnlngdIVINDVSYSY---GYGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLL 520
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 528 CGLCPPSDGFASIYGHRVSEIDEMfEARKMIGICPQSDINFDVlTVEENLsILASIKGIPANNIIQEVQKVLLDLDMQAI 607
Cdd:TIGR01193 521 VGFFQARSGEILLNGFSLKDIDRH-TLRQFINYLPQEPYIFSG-SILENL-LLGAKENVSQDEIWAACEIAEIKDDIENM 597
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 608 K-------DNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRH-IVWNLLKYRkaNRVTVFSTHFMDEADiL 679
Cdd:TIGR01193 598 PlgyqtelSEEGSSISGGQKQRIALARALLTDSKVLILDESTSNLDTITEKkIVNNLLNLQ--DKTIIFVAHRLSVAK-Q 674
|
250 260 270
....*....|....*....|....*....|.
gi 146134400 680 ADRKAVISQGMLKCVGSSIFLKSKWGIGYRL 710
Cdd:TIGR01193 675 SDKIIVLDHGKIIEQGSHDELLDRNGFYASL 705
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
477-696 |
7.23e-16 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 81.04 E-value: 7.23e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTEnveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDemfeark 556
Cdd:PRK11650 3 GLKLQAVRKSYDGKTQ---VIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELE------- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 migicP-QSDI-----NFDV---LTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGI 627
Cdd:PRK11650 73 -----PaDRDIamvfqNYALyphMSVRENMAYGLKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGR 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 628 AVLGNPKILLLDEPTAGMDPcsrhivwnllKYRKANRV------------TVFSTHFMDEADILADRKAVISQGMLKCVG 695
Cdd:PRK11650 148 AIVREPAVFLFDEPLSNLDA----------KLRVQMRLeiqrlhrrlkttSLYVTHDQVEAMTLADRVVVMNGGVAEQIG 217
|
.
gi 146134400 696 S 696
Cdd:PRK11650 218 T 218
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
1313-1566 |
8.21e-16 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 79.82 E-value: 8.21e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1313 KVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESI----KCMGYCPQtnplWPD 1388
Cdd:PRK13646 20 HQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIrpvrKRIGMVFQ----FPE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1389 LTLQE---HFEIYGAVK--GMspgDMKEVISRITKAL-DL---KEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEP 1459
Cdd:PRK13646 96 SQLFEdtvEREIIFGPKnfKM---NLDEVKNYAHRLLmDLgfsRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEP 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1460 STGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLkskFGKGYfleiKLKDW-I 1538
Cdd:PRK13646 173 TAGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKEL---FKDKK----KLADWhI 245
|
250 260 270
....*....|....*....|....*....|...
gi 146134400 1539 ENLEIDRLQREI----QYIFPN-ASRQESFSSI 1566
Cdd:PRK13646 246 GLPEIVQLQYDFeqkyQTKLKDiALTEEEFVSL 278
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
501-695 |
8.63e-16 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 77.98 E-value: 8.63e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 501 SFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEmfeARKMIGICPQSDINFDVLTVEENLSiL 580
Cdd:TIGR01277 18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLAP---YQRPVSMLFQENNLFAHLTVRQNIG-L 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 581 ASIKGIPANNIIQE-VQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKY 659
Cdd:TIGR01277 94 GLHPGLKLNAEQQEkVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALVKQ 173
|
170 180 190
....*....|....*....|....*....|....*...
gi 146134400 660 --RKANRVTVFSTHFMDEADILADRKAVISQGMLKCVG 695
Cdd:TIGR01277 174 lcSERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVS 211
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1294-1520 |
9.15e-16 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 80.89 E-value: 9.15e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYDDKkdflhsrkttkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDygshssED--DE 1371
Cdd:COG3839 8 NVSKSYGGV-----------EALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGG------RDvtDL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1372 SIKC--MGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAG----------IKR 1439
Cdd:COG3839 71 PPKDrnIAMVFQSYALYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGqrqrvalgraLVR 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1440 klcfalsmlgNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQH 1519
Cdd:COG3839 151 ----------EPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEE 220
|
.
gi 146134400 1520 L 1520
Cdd:COG3839 221 L 221
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1319-1464 |
9.75e-16 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 79.00 E-value: 9.75e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIflgdygshssEDDESIKcMGYCPQT---NPLWPdLTLQEHF 1395
Cdd:PRK09544 23 VSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI----------KRNGKLR-IGYVPQKlylDTTLP-LTVNRFL 90
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1396 EIYGAVKgmsPGDMKEVISRITKAldlkeHL-QKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMD 1464
Cdd:PRK09544 91 RLRPGTK---KEDILPALKRVQAG-----HLiDAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVD 152
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
1319-1511 |
1.03e-15 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 76.49 E-value: 1.03e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQtnplwpDLTLqehFeiy 1398
Cdd:cd03246 21 VSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGDHVGYLPQ------DDEL---F--- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1399 gavkgmsPGDMKEVIsritkaldlkehlqktvkkLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRtA 1478
Cdd:cd03246 89 -------SGSIAENI-------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQAIA-A 141
|
170 180 190
....*....|....*....|....*....|...
gi 146134400 1479 FKNKKRAALLTTHYMEEAEAvCDRVAIMVSGQL 1511
Cdd:cd03246 142 LKAAGATRIVIAHRPETLAS-ADRILVLEDGRV 173
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
485-692 |
1.27e-15 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 77.93 E-value: 1.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 485 KSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEAR---KMIGIC 561
Cdd:PRK11629 13 KRYQEGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAElrnQKLGFI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 562 PQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEP 641
Cdd:PRK11629 93 YQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEP 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 146134400 642 TAGMDPCSRHIVWNLLKYRKANRVTVF--STHFMDEADILaDRKAVISQGMLK 692
Cdd:PRK11629 173 TGNLDARNADSIFQLLGELNRLQGTAFlvVTHDLQLAKRM-SRQLEMRDGRLT 224
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
1319-1518 |
1.30e-15 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 78.66 E-value: 1.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQEHFEIY 1398
Cdd:PRK13548 21 VSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELARRRAVLPQHSSLSFPFTVEEVVAMG 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1399 GAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFA--LSML----GNPQVTLLDEPSTGMDPRAKQHMW 1472
Cdd:PRK13548 101 RAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLArvLAQLwepdGPPRWLLLDEPTSALDLAHQHHVL 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1473 RAIRTAFKNKKRAAL-------LTTHYmeeaeavCDRVAIMVSGQLRCIGTVQ 1518
Cdd:PRK13548 181 RLARQLAHERGLAVIvvlhdlnLAARY-------ADRIVLLHQGRLVADGTPA 226
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
474-703 |
1.52e-15 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 78.55 E-value: 1.52e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 474 GKEAIRISGIQKSYRKkTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCP------PSDGFASIYGHRVSE 547
Cdd:PRK14246 4 GKSAEDVFNISRLYLY-INDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEiydskiKVDGKVLYFGKDIFQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 548 IDEMfEARKMIGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEV-----QKVLLDLDMQAIKDNQAKKLSGGQKRK 622
Cdd:PRK14246 83 IDAI-KLRKEVGMVFQQPNPFPHLSIYDNIAYPLKSHGIKEKREIKKIveeclRKVGLWKEVYDRLNSPASQLSGGQQQR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 623 LSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSS--IFL 700
Cdd:PRK14246 162 LTIARALALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSneIFT 241
|
...
gi 146134400 701 KSK 703
Cdd:PRK14246 242 SPK 244
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
479-689 |
1.55e-15 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 81.50 E-value: 1.55e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 479 RISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYG--HRVSEIDEMFEArk 556
Cdd:PRK11288 6 SFDGIGKTF----PGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGqeMRFASTTAALAA-- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 miGIC---------PQsdinfdvLTVEENLSI--LASIKG-IPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLS 624
Cdd:PRK11288 80 --GVAiiyqelhlvPE-------MTVAENLYLgqLPHKGGiVNRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVE 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 625 VGIAVLGNPKILLLDEPTAGMDpcSRHIVwNLLK----YRKANRVTVFSTHFMDEADILADRKAVISQG 689
Cdd:PRK11288 151 IAKALARNARVIAFDEPTSSLS--AREIE-QLFRvireLRAEGRVILYVSHRMEEIFALCDAITVFKDG 216
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
1319-1520 |
2.16e-15 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 77.49 E-value: 2.16e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshsseDDESIkcMGYCP---------QTNPLWPDL 1389
Cdd:COG3840 18 FDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILW---------NGQDL--TALPPaerpvsmlfQENNLFPHL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1390 TLQEHFEIygavkGMSPG-----DMKEVISRITKALDLKEHLQktvkKLPA----GIKRKLCFALSMLGNPQVTLLDEPS 1460
Cdd:COG3840 87 TVAQNIGL-----GLRPGlkltaEQRAQVEQALERVGLAGLLD----RLPGqlsgGQRQRVALARCLVRKRPILLLDEPF 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1461 TGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL 1520
Cdd:COG3840 158 SALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAAL 217
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
478-691 |
3.65e-15 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 77.54 E-value: 3.65e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYR-----KKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEID--E 550
Cdd:TIGR02769 3 LEVRDVTHTYRtgglfGAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLDrkQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 551 MFEARKMIGICPQSDINfdvlTVEENLSILASIkGIPANNII-----QEVQKVLLDLDMQAIKDNQAKK----LSGGQKR 621
Cdd:TIGR02769 83 RRAFRRDVQLVFQDSPS----AVNPRMTVRQII-GEPLRHLTsldesEQKARIAELLDMVGLRSEDADKlprqLSGGQLQ 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146134400 622 KLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVT--VFSTHFMDEADILADRKAVISQGML 691
Cdd:TIGR02769 158 RINIARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTayLFITHDLRLVQSFCQRVAVMDKGQI 229
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
1309-1516 |
4.10e-15 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 76.38 E-value: 4.10e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1309 RKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshsseDDESI---------KCMGYC 1379
Cdd:cd03244 13 RPNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILI---------DGVDIskiglhdlrSRISII 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1380 PQtNPLWPDLTLQEH---------FEIYGAVKGMSpgdMKEVISRITKALDLKEHLQKtvKKLPAGIKRKLCFALSMLGN 1450
Cdd:cd03244 84 PQ-DPVLFSGTIRSNldpfgeysdEELWQALERVG---LKEFVESLPGGLDTVVEEGG--ENLSVGQRQLLCLARALLRK 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 1451 PQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNkkRAALLTTHYMeeaEAV--CDRVAIMVSGQLRCIGT 1516
Cdd:cd03244 158 SKILVLDEATASVDPETDALIQKTIREAFKD--CTVLTIAHRL---DTIidSDRILVLDKGRVVEFDS 220
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
495-695 |
4.25e-15 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 76.80 E-value: 4.25e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 495 EALRNLSFDIYEGQITALLGHSGTGKSTLM---NILCGLCPPS--DGFASIYGHRVSEID-EMFEARKMIGICPQSDINF 568
Cdd:PRK14267 18 HVIKGVDLKIPQNGVFALMGPSGCGKSTLLrtfNRLLELNEEArvEGEVRLFGRNIYSPDvDPIEVRREVGMVFQYPNPF 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 569 DVLTVEENLSILASIKGI--PANNIIQEVQKVLLDLDM-QAIKD---NQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPT 642
Cdd:PRK14267 98 PHLTIYDNVAIGVKLNGLvkSKKELDERVEWALKKAALwDEVKDrlnDYPSNLSGGQRQRLVIARALAMKPKILLMDEPT 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 146134400 643 AGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVG 695
Cdd:PRK14267 178 ANIDPVGTAKIEELLFELKKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVG 230
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
1294-1528 |
4.31e-15 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 75.64 E-value: 4.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYDDKKdFLHSrkttkvatkyISFCVKKGEILGLLGPNGAGKSTVINTLVG--DVEPTSGKIFLgdygshsseDDE 1371
Cdd:cd03217 5 DLHVSVGGKE-ILKG----------VNLTIKKGEVHALMGPNGSGKSTLAKTIMGhpKYEVTEGEILF---------KGE 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1372 SIKCMGycpqtnplwPD--------LTLQEHFEIYGaVK----------GMSPGDMKEVisritkaldlkEHLQktvkkl 1433
Cdd:cd03217 65 DITDLP---------PEerarlgifLAFQYPPEIPG-VKnadflryvneGFSGGEKKRN-----------EILQ------ 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1434 pagikrklcfalSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTaFKNKKRAALLTTHYMEEAEAV-CDRVAIMVSGQLR 1512
Cdd:cd03217 118 ------------LLLLEPDLAILDEPDSGLDIDALRLVAEVINK-LREEGKSVLIITHYQRLLDYIkPDRVHVLYDGRIV 184
|
250
....*....|....*.
gi 146134400 1513 CIGTVQHLKSKFGKGY 1528
Cdd:cd03217 185 KSGDKELALEIEKKGY 200
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
496-689 |
4.34e-15 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 77.05 E-value: 4.34e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 496 ALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDemfeARKmiGICPQSDINFDVLTVEE 575
Cdd:PRK11248 16 ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPG----AER--GVVFQNEGLLPWRNVQD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 576 NLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWN 655
Cdd:PRK11248 90 NVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTREQMQT 169
|
170 180 190
....*....|....*....|....*....|....*.
gi 146134400 656 LL--KYRKANRVTVFSTHFMDEADILADRKAVISQG 689
Cdd:PRK11248 170 LLlkLWQETGKQVLLITHDIEEAVFMATELVLLSPG 205
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1306-1514 |
5.08e-15 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 79.83 E-value: 5.08e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1306 LHSRKTTKVatKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFL-GDYGSHSSEDDESIKCMGYCPQT-- 1382
Cdd:PRK09700 271 VTSRDRKKV--RDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLnGKDISPRSPLDAVKKGMAYITESrr 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1383 -NPLWPDLTLQEHFEIY---------GAVKGMSPGDMKEVISRITKALDLKEH-LQKTVKKLPAGIKRKLCFALSMLGNP 1451
Cdd:PRK09700 349 dNGFFPNFSIAQNMAISrslkdggykGAMGLFHEVDEQRTAENQRELLALKCHsVNQNITELSGGNQQKVLISKWLCCCP 428
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1452 QVTLLDEPSTGMDPRAKQHMWRAIRTaFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCI 1514
Cdd:PRK09700 429 EVIIFDEPTRGIDVGAKAEIYKVMRQ-LADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQI 490
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
1294-1482 |
6.79e-15 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 75.72 E-value: 6.79e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYDDKKDFLHSrkttkvatkyISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESI 1373
Cdd:cd03254 7 NVNFSYDEKKPVLKD----------INFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1374 KCMGYCPQTNPLWPDlTLQEHFEIygavkGMSPGDMKEVI--SRITKALDLKEHLQK---TV-----KKLPAGIKRKLCF 1443
Cdd:cd03254 77 SMIGVVLQDTFLFSG-TIMENIRL-----GRPNATDEEVIeaAKEAGAHDFIMKLPNgydTVlgengGNLSQGERQLLAI 150
|
170 180 190
....*....|....*....|....*....|....*....
gi 146134400 1444 ALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNK 1482
Cdd:cd03254 151 ARAMLRDPKILILDEATSNIDTETEKLIQEALEKLMKGR 189
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
498-643 |
7.16e-15 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 75.23 E-value: 7.16e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 498 RNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFeARKMIGICPQSDINfDVLTVEENL 577
Cdd:PRK13538 18 SGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDEY-HQDLLYLGHQPGIK-TELTALENL 95
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 578 SILASIKGIPANNIIQEV-QKVLLdldmQAIKDNQAKKLSGGQKRKlsVGIA--VLGNPKILLLDEP-TA 643
Cdd:PRK13538 96 RFYQRLHGPGDDEALWEAlAQVGL----AGFEDVPVRQLSAGQQRR--VALArlWLTRAPLWILDEPfTA 159
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
1323-1510 |
7.55e-15 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 75.91 E-value: 7.55e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1323 VKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIflgdygshssedDESIKCMGYCPQTnpLWPDLTLQEHFEIYGAVK 1402
Cdd:cd03237 22 ISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDI------------EIELDTVSYKPQY--IKADYEGTVRDLLSSITK 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1403 GMspGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNK 1482
Cdd:cd03237 88 DF--YTHPYFKTEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRRFAENN 165
|
170 180 190
....*....|....*....|....*....|
gi 146134400 1483 KRAALLTTH--YMeeAEAVCDRVaIMVSGQ 1510
Cdd:cd03237 166 EKTAFVVEHdiIM--IDYLADRL-IVFEGE 192
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
475-671 |
7.82e-15 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 76.46 E-value: 7.82e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 475 KEAIRISGIQKSYRKKTEnveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEmfea 554
Cdd:PRK15056 4 QAGIVVNDVTVTWRNGHT---ALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQ---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 555 RKMIGICPQS---DINFDVLTveENLSILA-----SIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVG 626
Cdd:PRK15056 77 KNLVAYVPQSeevDWSFPVLV--EDVVMMGryghmGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLA 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 146134400 627 IAVLGNPKILLLDEPTAGMDPCSRHIVWNLLK-YRKANRVTVFSTH 671
Cdd:PRK15056 155 RAIAQQGQVILLDEPFTGVDVKTEARIISLLReLRDEGKTMLVSTH 200
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
1319-1511 |
7.96e-15 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 75.32 E-value: 7.96e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQtnplwpDLTLqehfeIY 1398
Cdd:cd03245 23 VSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLRRNIGYVPQ------DVTL-----FY 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1399 GAVK-----GMSPGDMKEVI--SRITKALDLkehlqktVKKLPAGIKRKLC---FALS------------MLGNPQVTLL 1456
Cdd:cd03245 92 GTLRdnitlGAPLADDERILraAELAGVTDF-------VNKHPNGLDLQIGergRGLSggqrqavalaraLLNDPPILLL 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 1457 DEPSTGMDPRAKQHMWRAIRTAFKNKkrAALLTTHYMeEAEAVCDRVAIMVSGQL 1511
Cdd:cd03245 165 DEPTSAMDMNSEERLKERLRQLLGDK--TLIIITHRP-SLLDLVDRIIVMDSGRI 216
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
476-682 |
8.05e-15 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 75.55 E-value: 8.05e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 476 EAIRISGIQKSYRKKTEN---VEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfaSI-YGHRVSEID-- 549
Cdd:COG4778 3 TLLEVENLSKTFTLHLQGgkrLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSG--SIlVRHDGGWVDla 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 550 -----EMFEARK-MIGICPQsdinFdvLTVeenlsilasIKGIPANNIiqeVQKVLLDLDM-QAIKDNQAKKL------- 615
Cdd:COG4778 81 qasprEILALRRrTIGYVSQ----F--LRV---------IPRVSALDV---VAEPLLERGVdREEARARARELlarlnlp 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 616 -----------SGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSThFMDEA--DILADR 682
Cdd:COG4778 143 erlwdlppatfSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIGI-FHDEEvrEAVADR 221
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
1303-1516 |
8.37e-15 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 78.54 E-value: 8.37e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1303 KDFLHSRKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDE----SIKCMGY 1378
Cdd:PRK10070 31 KEQILEKTGLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAElrevRRKKIAM 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1379 CPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDE 1458
Cdd:PRK10070 111 VFQSFALMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDE 190
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 1459 PSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGT 1516
Cdd:PRK10070 191 AFSALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGT 248
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
1294-1511 |
8.76e-15 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 75.47 E-value: 8.76e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYDDKKDFLHSrkttkvatkyISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDE-- 1371
Cdd:COG2884 6 NVSKRYPGGREALSD----------VSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREip 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1372 ----SIkcmGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEvisRITKALD---LKEHLQKTVKKLPAGIKRKLCFA 1444
Cdd:COG2884 76 ylrrRI---GVVFQDFRLLPDRTVYENVALPLRVTGKSRKEIRR---RVREVLDlvgLSDKAKALPHELSGGEQQRVAIA 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 1445 LSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAfkNKKRAA-LLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:COG2884 150 RALVNRPELLLADEPTGNLDPETSWEIMELLEEI--NRRGTTvLIATHDLELVDRMPKRVLELEDGRL 215
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
1319-1516 |
8.96e-15 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 76.70 E-value: 8.96e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQEHFEI- 1397
Cdd:PRK13643 25 IDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQKEIKPVRKKVGVVFQFPESQLFEETVLk 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1398 ---YGAVK-GMSPGDMKEVISRITKALDL-KEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMW 1472
Cdd:PRK13643 105 dvaFGPQNfGIPKEKAEKIAAEKLEMVGLaDEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPKARIEMM 184
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 146134400 1473 RAIRTAFKNKKrAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGT 1516
Cdd:PRK13643 185 QLFESIHQSGQ-TVVLVTHLMDDVADYADYVYLLEKGHIISCGT 227
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
478-696 |
9.67e-15 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 75.82 E-value: 9.67e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSeideMFEARKM 557
Cdd:PRK11231 3 LRTENLTVGYGTKR----ILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPIS----MLSSRQL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 ---IGICPQsdinfdVLTVEENLSI--LASIKGIPANNII--------QEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLS 624
Cdd:PRK11231 75 arrLALLPQ------HHLTPEGITVreLVAYGRSPWLSLWgrlsaednARVNQAMEQTRINHLADRRLTDLSGGQRQRAF 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 625 VGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFST-HFMDEADILADRKAVISQGMLKCVGS 696
Cdd:PRK11231 149 LAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVlHDLNQASRYCDHLVVLANGHVMAQGT 221
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
1290-1511 |
1.08e-14 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 73.89 E-value: 1.08e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKKdflhsrkttKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSED 1369
Cdd:cd03247 1 LSINNVSFSYPEQE---------QQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEK 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 DESiKCMGYCPQTNPLWpDLTLQEHFEiygavkgmspgdmkevisritkaldlkehlqktvKKLPAGIKRKLCFALSMLG 1449
Cdd:cd03247 72 ALS-SLISVLNQRPYLF-DTTLRNNLG----------------------------------RRFSGGERQRLALARILLQ 115
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146134400 1450 NPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKkrAALLTTHYMEEAEAVcDRVAIMVSGQL 1511
Cdd:cd03247 116 DAPIVLLDEPTVGLDPITERQLLSLIFEVLKDK--TLIWITHHLTGIEHM-DKILFLENGKI 174
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
1319-1491 |
1.26e-14 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 74.50 E-value: 1.26e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIflgDYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQEHFEIY 1398
Cdd:PRK13543 30 LDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQI---QIDGKTATRGDRSRFMAYLGHLPGLKADLSTLENLHFL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1399 GAVKGMSPgdmKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIrTA 1478
Cdd:PRK13543 107 CGLHGRRA---KQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLEGITLVNRMI-SA 182
|
170
....*....|...
gi 146134400 1479 FKNKKRAALLTTH 1491
Cdd:PRK13543 183 HLRGGGAALVTTH 195
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
1312-1518 |
1.50e-14 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 77.05 E-value: 1.50e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1312 TKVATKyISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI-FLGDYGSHSSEDDESIkcmGYCPQTNPLWPDLT 1390
Cdd:PRK10851 15 TQVLND-ISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIrFHGTDVSRLHARDRKV---GFVFQHYALFRHMT 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1391 LQEH--FEIYGAVKGMSPgDMKEVISRITKALDLK--EHL-QKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDP 1465
Cdd:PRK10851 91 VFDNiaFGLTVLPRRERP-NAAAIKAKVTQLLEMVqlAHLaDRYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDA 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1466 RAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQ 1518
Cdd:PRK10851 170 QVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPD 222
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
1277-1511 |
1.71e-14 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 78.17 E-value: 1.71e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1277 ELMGCQCCE--EKPAIMVCNLHKEyddkkDFLHsrkttkvatkyISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTS 1354
Cdd:PRK15439 254 ELPGNRRQQaaGAPVLTVEDLTGE-----GFRN-----------ISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARG 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1355 GKIFLGDYG-SHSSEDDESIKCMGYCP---QTNPLWPDLTLQehFEIYGAVKG-----MSPGDMKEVISRITKALDLK-E 1424
Cdd:PRK15439 318 GRIMLNGKEiNALSTAQRLARGLVYLPedrQSSGLYLDAPLA--WNVCALTHNrrgfwIKPARENAVLERYRRALNIKfN 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1425 HLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKnKKRAALLTTHYMEEAEAVCDRVA 1504
Cdd:PRK15439 396 HAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARNDIYQLIRSIAA-QNVAVLFISSDLEEIEQMADRVL 474
|
....*..
gi 146134400 1505 IMVSGQL 1511
Cdd:PRK15439 475 VMHQGEI 481
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
1303-1516 |
2.09e-14 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 75.50 E-value: 2.09e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1303 KDFLHSRKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGdyGSHSSEDDESI----KCMGY 1378
Cdd:PRK13639 5 RDLKYSYPDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIK--GEPIKYDKKSLlevrKTVGI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1379 CPQtNPlwPDLTLQEHFEIYGAVKGMSPG-DMKEVISRITKAL---DLKEHLQKTVKKLPAGIKRKLCFA--LSMlgNPQ 1452
Cdd:PRK13639 83 VFQ-NP--DDQLFAPTVEEDVAFGPLNLGlSKEEVEKRVKEALkavGMEGFENKPPHHLSGGQKKRVAIAgiLAM--KPE 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 1453 VTLLDEPSTGMDPRAKQHMWRAIRTAfkNKKRAAL-LTTHYMEEAEAVCDRVAIMVSGQLRCIGT 1516
Cdd:PRK13639 158 IIVLDEPTSGLDPMGASQIMKLLYDL--NKEGITIiISTHDVDLVPVYADKVYVMSDGKIIKEGT 220
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
1290-1503 |
2.49e-14 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 71.71 E-value: 2.49e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKKDFlhsrkttkvatKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGShssed 1369
Cdd:cd03221 1 IELENLSKTYGGKLLL-----------KDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTVK----- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 desikcMGYCPQtnplwpdltlqehfeiygavkgMSPGDmkevisritkaldlkehlqktvkklpagiKRKLCFALSMLG 1449
Cdd:cd03221 65 ------IGYFEQ----------------------LSGGE-----------------------------KMRLALAKLLLE 87
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 146134400 1450 NPQVTLLDEPSTGMDPRAKQhmwrAIRTAFKNKKRAALLTTHYMEEAEAVCDRV 1503
Cdd:cd03221 88 NPNLLLLDEPTNHLDLESIE----ALEEALKEYPGTVILVSHDRYFLDQVATKI 137
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
1313-1551 |
2.56e-14 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 75.44 E-value: 2.56e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1313 KVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCM----GYCPQtnplWPd 1388
Cdd:PRK13634 20 RRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAGKKNKKLKPLrkkvGIVFQ----FP- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1389 ltlqEH--FE-------IYGAVK-GMSPGDMKEVISRITKALDLKEH-LQKTVKKLPAGIKRKLCFA--LSMlgNPQVTL 1455
Cdd:PRK13634 95 ----EHqlFEetvekdiCFGPMNfGVSEEDAKQKAREMIELVGLPEElLARSPFELSGGQMRRVAIAgvLAM--EPEVLV 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1456 LDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKfgkgyfleiklK 1535
Cdd:PRK13634 169 LDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFAD-----------P 237
|
250 260
....*....|....*....|.
gi 146134400 1536 DWIENLEID-----RLQREIQ 1551
Cdd:PRK13634 238 DELEAIGLDlpetvKFKRALE 258
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
1303-1520 |
2.95e-14 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 74.84 E-value: 2.95e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1303 KDFLHSRKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQT 1382
Cdd:PRK13652 7 RDLCYSYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREVRKFVGLVFQN 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1383 nplwPD----LTLQEHFEIYGAVK-GMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLD 1457
Cdd:PRK13652 87 ----PDdqifSPTVEQDIAFGPINlGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLD 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1458 EPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL 1520
Cdd:PRK13652 163 EPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEI 225
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
492-689 |
3.11e-14 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 74.02 E-value: 3.11e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 492 ENVEALRN---LSFD--IYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGhrvSEIDEMFEARKMIGICPQSDI 566
Cdd:COG3840 5 DDLTYRYGdfpLRFDltIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNG---QDLTALPPAERPVSMLFQENN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 567 NFDVLTVEENLSIlasikGIPAN---------NIIQEVQKVLLDlDMQAIKDNQakkLSGGQKRKlsVGIA---VLGNPk 634
Cdd:COG3840 82 LFPHLTVAQNIGL-----GLRPGlkltaeqraQVEQALERVGLA-GLLDRLPGQ---LSGGQRQR--VALArclVRKRP- 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 635 ILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADILADRKAVISQG 689
Cdd:COG3840 150 ILLLDEPFSALDPALRQEMLDLVDelCRERGLTVLMVTHDPEDAARIADRVLLVADG 206
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
500-646 |
3.22e-14 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 73.30 E-value: 3.22e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 500 LSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFeARKMIGICPQSDINfDVLTVEENLSI 579
Cdd:cd03231 19 LSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSI-ARGLLYLGHAPGIK-TTLSVLENLRF 96
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 580 LASIKGIPAnniiqeVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMD 646
Cdd:cd03231 97 WHADHSDEQ------VEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALD 157
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
1286-1520 |
3.24e-14 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 75.05 E-value: 3.24e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1286 EKPAIMVCNLHKEYDDkkdflhsrkTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGdygsH 1365
Cdd:PRK13635 2 KEEIIRVEHISFRYPD---------AATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVG----G 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1366 SSEDDESI----KCMGYCPQTnplwPD-----LTLQEHFEIYGAVKGMSPGDMkevISRITKALDL---KEHLQKTVKKL 1433
Cdd:PRK13635 69 MVLSEETVwdvrRQVGMVFQN----PDnqfvgATVQDDVAFGLENIGVPREEM---VERVDQALRQvgmEDFLNREPHRL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1434 PAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTaFKNKKRAALLT-THYMEEAeAVCDRVAIMVSGQLR 1512
Cdd:PRK13635 142 SGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLETVRQ-LKEQKGITVLSiTHDLDEA-AQADRVIVMNKGEIL 219
|
....*...
gi 146134400 1513 CIGTVQHL 1520
Cdd:PRK13635 220 EEGTPEEI 227
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
477-689 |
3.40e-14 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 74.40 E-value: 3.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfaSIyghRVSEID------- 549
Cdd:PRK11264 3 AIEVKNLVKKFHGQT----VLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAG--TI---RVGDITidtarsl 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 550 -----EMFEARKMIGICPQSDINFDVLTVEENlsILAS---IKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKR 621
Cdd:PRK11264 74 sqqkgLIRQLRQHVGFVFQNFNLFPHRTVLEN--IIEGpviVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQ 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146134400 622 KLSVGIAVLGNPKILLLDEPTAGMDPcsrHIVWNLLKYRKA----NRVTVFSTHFMDEADILADRKAVISQG 689
Cdd:PRK11264 152 RVAIARALAMRPEVILFDEPTSALDP---ELVGEVLNTIRQlaqeKRTMVIVTHEMSFARDVADRAIFMDQG 220
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1319-1525 |
3.68e-14 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 76.42 E-value: 3.68e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQEHFEI- 1397
Cdd:PRK09536 22 VDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAASRRVASVPQDTSLSFEFDVRQVVEMg 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1398 ----YGAVKGMSPGDmKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDprakqhMWR 1473
Cdd:PRK09536 102 rtphRSRFDTWTETD-RAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASLD------INH 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1474 AIRT-----AFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIG------TVQHLKSKFG 1525
Cdd:PRK09536 175 QVRTlelvrRLVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGppadvlTADTLRAAFD 237
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
478-697 |
4.13e-14 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 74.28 E-value: 4.13e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKtenvEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLC---PPSDGFASIYGHRVSE----IDE 550
Cdd:PRK09984 5 IRVEKLAKTFNQH----QALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLItgdKSAGSHIELLGRTVQRegrlARD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 551 MFEARKMIGICPQSDINFDVLTVEENLsILASIKGIP---------ANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKR 621
Cdd:PRK09984 81 IRKSRANTGYIFQQFNLVNRLSVLENV-LIGALGSTPfwrtcfswfTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQ 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 622 KLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLK-YRKANRVTVFST-HFMDEADILADRKAVISQGMLKCVGSS 697
Cdd:PRK09984 160 RVAIARALMQQAKVILADEPIASLDPESARIVMDTLRdINQNDGITVVVTlHQVDYALRYCERIVALRQGHVFYDGSS 237
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
1301-1568 |
4.17e-14 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 74.66 E-value: 4.17e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1301 DKKDFLHSRKT--TKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSS-----EDDESI 1373
Cdd:PRK13645 10 DNVSYTYAKKTpfEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIPANlkkikEVKRLR 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1374 KCMGYCPQtnplWPDLTL-QEHFEIYGAVKGMSPG-DMKEVISRITKALDL----KEHLQKTVKKLPAGIKRKLCFA--L 1445
Cdd:PRK13645 90 KEIGLVFQ----FPEYQLfQETIEKDIAFGPVNLGeNKQEAYKKVPELLKLvqlpEDYVKRSPFELSGGQKRRVALAgiI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1446 SMLGNPQVtlLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTV------QH 1519
Cdd:PRK13645 166 AMDGNTLV--LDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPfeifsnQE 243
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1520 LKSKFG----KGYFLEIKLKdwieNLEIDRLQREIQYIfpnasrqESFSSILA 1568
Cdd:PRK13645 244 LLTKIEidppKLYQLMYKLK----NKGIDLLNKNIRTI-------EEFAKELA 285
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
490-658 |
4.22e-14 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 78.23 E-value: 4.22e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 490 KTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPP---SDGFASIYGHrvsEIDEMFEARkmIGICPQSDI 566
Cdd:TIGR00956 772 KKEKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAERVTTgviTGGDRLVNGR---PLDSSFQRS--IGYVQQQDL 846
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 567 NFDVLTVEENLSILASIKgIPANNIIQE----VQKVLLDLDMQAIKDN----QAKKLSGGQKRKLSVGIAVLGNPKILL- 637
Cdd:TIGR00956 847 HLPTSTVRESLRFSAYLR-QPKSVSKSEkmeyVEEVIKLLEMESYADAvvgvPGEGLNVEQRKRLTIGVELVAKPKLLLf 925
|
170 180
....*....|....*....|.
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLK 658
Cdd:TIGR00956 926 LDEPTSGLDSQTAWSICKLMR 946
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
1294-1524 |
4.41e-14 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 74.08 E-value: 4.41e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEY-------DDKKDFLHSRKTTKV--ATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIflgdygs 1364
Cdd:PRK13546 9 NVTKEYriyrtnkERMKDALIPKHKNKTffALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKV------- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1365 hssEDDESIKCMGYCPQTNPlwpDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFA 1444
Cdd:PRK13546 82 ---DRNGEVSVIAISAGLSG---QLTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFS 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1445 LSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKF 1524
Cdd:PRK13546 156 INITVNPDILVIDEALSVGDQTFAQKCLDKIY-EFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPKY 234
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
1276-1516 |
6.08e-14 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 75.37 E-value: 6.08e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1276 KELMGCQCCEEKPAIMVCNLHKEYDDKKdflhsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSG 1355
Cdd:PRK09452 1 SKKLNKQPSSLSPLVELRGISKSFDGKE-----------VISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSG 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1356 KIFLGDygshsseddesiKCMGYCP----------QTNPLWPDLTLQEHFEiYGAVKGMSPGDmkEVISRITKAL---DL 1422
Cdd:PRK09452 70 RIMLDG------------QDITHVPaenrhvntvfQSYALFPHMTVFENVA-FGLRMQKTPAA--EITPRVMEALrmvQL 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1423 KEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMwraiRTAFKNKKRAALLT----THYMEEAEA 1498
Cdd:PRK09452 135 EEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQM----QNELKALQRKLGITfvfvTHDQEEALT 210
|
250
....*....|....*...
gi 146134400 1499 VCDRVAIMVSGQLRCIGT 1516
Cdd:PRK09452 211 MSDRIVVMRDGRIEQDGT 228
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
1320-1511 |
6.23e-14 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 73.08 E-value: 6.23e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1320 SFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYcpQTNPLWPDLTLQEHFEIyg 1399
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSRRPVSMLF--QENNLFSHLTVAQNIGL-- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1400 avkGMSPG-----DMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRA 1474
Cdd:PRK10771 95 ---GLNPGlklnaAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTL 171
|
170 180 190
....*....|....*....|....*....|....*..
gi 146134400 1475 IRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:PRK10771 172 VSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRI 208
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
1290-1527 |
6.34e-14 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 74.00 E-value: 6.34e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKKDflhsrkttKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGdyGSHSSED 1369
Cdd:PRK13650 5 IEVKNLTFKYKEDQE--------KYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIID--GDLLTEE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 D--ESIKCMGYCPQTnplwPD-----LTLQEHFEIYGAVKGMSPGDMKEvisRITKALDL---KEHLQKTVKKLPAGIKR 1439
Cdd:PRK13650 75 NvwDIRHKIGMVFQN----PDnqfvgATVEDDVAFGLENKGIPHEEMKE---RVNEALELvgmQDFKEREPARLSGGQKQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1440 KLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAeAVCDRVAIMVSGQLRCIGTVQH 1519
Cdd:PRK13650 148 RVAIAGAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTPRE 226
|
....*...
gi 146134400 1520 LkskFGKG 1527
Cdd:PRK13650 227 L---FSRG 231
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
1319-1511 |
7.88e-14 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 72.44 E-value: 7.88e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDY---GSHSSEDDESIKCMGYCPQTNPLWPDLTLQEHF 1395
Cdd:cd03292 20 INISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQdvsDLRGRAIPYLRRKIGVVFQDFRLLPDRNVYENV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1396 EIYGAVKGMSPgdmKEVISRITKALDLKEhLQKTVKKLPAGIKR----KLCFALSMLGNPQVTLLDEPSTGMDPrakQHM 1471
Cdd:cd03292 100 AFALEVTGVPP---REIRKRVPAALELVG-LSHKHRALPAELSGgeqqRVAIARAIVNSPTILIADEPTGNLDP---DTT 172
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 146134400 1472 WRAIRTAFKNKKRAA--LLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:cd03292 173 WEIMNLLKKINKAGTtvVVATHAKELVDTTRHRVIALERGKL 214
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
483-646 |
9.55e-14 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 74.76 E-value: 9.55e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 483 IQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSeiDEMFEARKmIGICP 562
Cdd:PRK11432 12 ITKRFGSNT----VIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVT--HRSIQQRD-ICMVF 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 563 QSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPT 642
Cdd:PRK11432 85 QSYALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPL 164
|
....
gi 146134400 643 AGMD 646
Cdd:PRK11432 165 SNLD 168
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
489-689 |
1.08e-13 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 75.63 E-value: 1.08e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 489 KKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGH----RVSEIDEMfeARKMIGICPQS 564
Cdd:TIGR02633 9 KTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTWDGEIYWSgsplKASNIRDT--ERAGIVIIHQE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 565 dinfdvLTVEENLSILASI--------KG--IPANNIIQEVQKVLLDLDMQAIKDNQA-KKLSGGQKRKLSVGIAVLGNP 633
Cdd:TIGR02633 87 ------LTLVPELSVAENIflgneitlPGgrMAYNAMYLRAKNLLRELQLDADNVTRPvGDYGGGQQQLVEIAKALNKQA 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 634 KILLLDEPTAGMDPCSRHIVWNLLKYRKANRVT-VFSTHFMDEADILADRKAVISQG 689
Cdd:TIGR02633 161 RLLILDEPSSSLTEKETEILLDIIRDLKAHGVAcVYISHKLNEVKAVCDTICVIRDG 217
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
489-697 |
1.14e-13 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 75.61 E-value: 1.14e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 489 KKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGL--CPPSDGfASIY------------------------G 542
Cdd:TIGR03269 8 KKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqYEPTSG-RIIYhvalcekcgyverpskvgepcpvcG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 543 HRVSEIDEMF---------EARKMIGICPQSDIN-FDVLTVEENlsILASIK--GIPANNIIQEVQKVLLDLDMQAIKDN 610
Cdd:TIGR03269 87 GTLEPEEVDFwnlsdklrrRIRKRIAIMLQRTFAlYGDDTVLDN--VLEALEeiGYEGKEAVGRAVDLIEMVQLSHRITH 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 611 QAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWN-LLKYRKANRVT-VFSTHFMDEADILADRKAVISQ 688
Cdd:TIGR03269 165 IARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNaLEEAVKASGISmVLTSHWPEVIEDLSDKAIWLEN 244
|
....*....
gi 146134400 689 GMLKCVGSS 697
Cdd:TIGR03269 245 GEIKEEGTP 253
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
1319-1491 |
1.34e-13 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 75.47 E-value: 1.34e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQTNPLWpDLTLQEHFEIy 1398
Cdd:TIGR02868 354 VSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVRRRVSVCAQDAHLF-DTTVRENLRL- 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1399 gAVKGMSPGDMKEVISRITKALDLKEH-------LQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHM 1471
Cdd:TIGR02868 432 -ARPDATDEELWAALERVGLADWLRALpdgldtvLGEGGARLSGGERQRLALARALLADAPILLLDEPTEHLDAETADEL 510
|
170 180
....*....|....*....|
gi 146134400 1472 WRAIRTAfkNKKRAALLTTH 1491
Cdd:TIGR02868 511 LEDLLAA--LSGRTVVLITH 528
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
1323-1507 |
1.45e-13 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 75.59 E-value: 1.45e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1323 VKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIflgdygshssedDESIKcMGYCPQTnpLWPD--LTLQEHfeIYGA 1400
Cdd:COG1245 363 IREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEV------------DEDLK-ISYKPQY--ISPDydGTVEEF--LRSA 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1401 VKGMSPGDMKEviSRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFK 1480
Cdd:COG1245 426 NTDDFGSSYYK--TEIIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAE 503
|
170 180
....*....|....*....|....*....
gi 146134400 1481 NKKRAALLTTH--YMeeAEAVCDRvaIMV 1507
Cdd:COG1245 504 NRGKTAMVVDHdiYL--IDYISDR--LMV 528
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
1319-1511 |
1.52e-13 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 75.33 E-value: 1.52e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGD----YGSHSSEDDESIKCMgYcpQTNPLWPDLTLQEH 1394
Cdd:PRK11288 23 ISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGqemrFASTTAALAAGVAII-Y--QELHLVPEMTVAEN 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1395 feIY--------GAVKGmspGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPR 1466
Cdd:PRK11288 100 --LYlgqlphkgGIVNR---RLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVIAFDEPTSSLSAR 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 146134400 1467 AKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:PRK11288 175 EIEQLFRVIR-ELRAEGRVILYVSHRMEEIFALCDAITVFKDGRY 218
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
477-684 |
1.57e-13 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 72.38 E-value: 1.57e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYrkKTENVeaLRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGF----------ASIYGHRVS 546
Cdd:PRK14258 7 AIKVNNLSFYY--DTQKI--LEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESEVrvegrveffnQNIYERRVN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 547 eIDEMFEARKMIGICPqsdiNFDVLTVEENLSILASIKGI-PANNIIQEVQKVLLDLDM-QAIKDN---QAKKLSGGQKR 621
Cdd:PRK14258 83 -LNRLRRQVSMVHPKP----NLFPMSVYDNVAYGVKIVGWrPKLEIDDIVESALKDADLwDEIKHKihkSALDLSGGQQQ 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 622 KLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYR--KANRVTVFSTHFMDEADILADRKA 684
Cdd:PRK14258 158 RLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLrlRSELTMVIVSHNLHQVSRLSDFTA 222
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
1296-1528 |
1.85e-13 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 75.31 E-value: 1.85e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1296 HKEYDDKKDFLHSRKTTKV--ATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGdyGSHSseddesi 1373
Cdd:PRK13545 18 NKPFDKLKDLFFRSKDGEYhyALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIK--GSAA------- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1374 kcmgYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQV 1453
Cdd:PRK13545 89 ----LIAISSGLNGQLTGIENIELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDI 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 1454 TLLDEP-STGMDPRAKQHMWRAirTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFG---KGY 1528
Cdd:PRK13545 165 LVIDEAlSVGDQTFTKKCLDKM--NEFKEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVDHYDeflKKY 241
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
474-705 |
2.01e-13 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 73.62 E-value: 2.01e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 474 GKEAIRISGIQKSYRKktenVEALRNLSFDIYEGQITALLGHSGTG--KSTLMNILCGlcpPSDG-----FASIYGHRVS 546
Cdd:NF000106 10 ARNAVEVRGLVKHFGE----VKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*G---PDAGrrpwrF*TWCANRRA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 547 eidemfeARKMIGIC-PQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSV 625
Cdd:NF000106 83 -------LRRTIG*HrPVR*GRRESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 626 GIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTV-FSTHFMDEADILADRKAVISQGMLKCVGSSIFLKSKW 704
Cdd:NF000106 156 AASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVlLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTKV 235
|
.
gi 146134400 705 G 705
Cdd:NF000106 236 G 236
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1289-1511 |
2.24e-13 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 71.70 E-value: 2.24e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1289 AIMVCNLHKEYDDKKdFLHSrkttkvatkyISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDY----GS 1364
Cdd:PRK11264 3 AIEVKNLVKKFHGQT-VLHG----------IDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDItidtAR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1365 HSSEDDESIKCM----GYCPQTNPLWPDLTLQEHFeIYG--AVKGMSPGDM----KEVISRItkALDLKEhlQKTVKKLP 1434
Cdd:PRK11264 72 SLSQQKGLIRQLrqhvGFVFQNFNLFPHRTVLENI-IEGpvIVKGEPKEEAtaraRELLAKV--GLAGKE--TSYPRRLS 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 1435 AGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:PRK11264 147 GGQQQRVAIARALAMRPEVILFDEPTSALDPELVGEVLNTIR-QLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRI 222
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
1289-1509 |
2.26e-13 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 72.46 E-value: 2.26e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1289 AIMVCNLHKEYDDKkdflhsrktTKvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSE 1368
Cdd:PRK13647 4 IIEVEDLHFRYKDG---------TK-ALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAEN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1369 DDESIKCMGYCPQ-------TNPLWPDLTlqehfeiYGAVK-GMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRK 1440
Cdd:PRK13647 74 EKWVRSKVGLVFQdpddqvfSSTVWDDVA-------FGPVNmGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKR 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 1441 LCFA--LSMlgNPQVTLLDEPSTGMDPRAKQHMwRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSG 1509
Cdd:PRK13647 147 VAIAgvLAM--DPDVIVLDEPMAYLDPRGQETL-MEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEG 214
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
1289-1464 |
2.57e-13 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 74.54 E-value: 2.57e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1289 AIMVCNLHKEYDDKKDFlhsrkttkvatKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIflgdygsHSSE 1368
Cdd:PRK15064 319 ALEVENLTKGFDNGPLF-----------KNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV-------KWSE 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1369 DDEsikcMGYCPQ--TNPLWPDLTLQEHFEIYgavkgMSPGDMKEVI-SRITKALDLKEHLQKTVKKLPAGIKRKLCFAL 1445
Cdd:PRK15064 381 NAN----IGYYAQdhAYDFENDLTLFDWMSQW-----RQEGDDEQAVrGTLGRLLFSQDDIKKSVKVLSGGEKGRMLFGK 451
|
170
....*....|....*....
gi 146134400 1446 SMLGNPQVTLLDEPSTGMD 1464
Cdd:PRK15064 452 LMMQKPNVLVMDEPTNHMD 470
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
1319-1516 |
2.84e-13 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 71.56 E-value: 2.84e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDygsHSSE--DDESIKCMGYCP--QTNPLWPDLTLQEH 1394
Cdd:PRK11300 24 VNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRG---QHIEglPGHQIARMGVVRtfQHVRLFREMTVIEN 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1395 FEI--YGAVK-GMSPGDMK---------EVISRITKALD---LKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEP 1459
Cdd:PRK11300 101 LLVaqHQQLKtGLFSGLLKtpafrraesEALDRAATWLErvgLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILMLDEP 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 1460 STGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGT 1516
Cdd:PRK11300 181 AAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGT 237
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
488-689 |
3.09e-13 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 74.18 E-value: 3.09e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 488 RKKTENVEA--LRN-LSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSeIDEMFEA-RKMIGICPQ 563
Cdd:PRK11288 257 RLRLDGLKGpgLREpISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPID-IRSPRDAiRAGIMLCPE 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 564 sDINFD----VLTVEENLSILASIKGIPANNII---QEVQKVLLDLDMQAIK----DNQAKKLSGG--QK----RKLSVG 626
Cdd:PRK11288 336 -DRKAEgiipVHSVADNINISARRHHLRAGCLInnrWEAENADRFIRSLNIKtpsrEQLIMNLSGGnqQKailgRWLSED 414
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 627 IavlgnpKILLLDEPTAGMDPCSRHIVWNLLkYRKANR---VTVFSTHFMdEADILADRKAVISQG 689
Cdd:PRK11288 415 M------KVILLDEPTRGIDVGAKHEIYNVI-YELAAQgvaVLFVSSDLP-EVLGVADRIVVMREG 472
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
1286-1511 |
3.42e-13 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 71.00 E-value: 3.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1286 EKPAIMVCNLHKEYDDKK---DFLHSrkttkvatkyISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGK-IFLG- 1360
Cdd:PRK11629 2 NKILLQCDNLCKRYQEGSvqtDVLHN----------VSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDvIFNGq 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1361 --DYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIK 1438
Cdd:PRK11629 72 pmSKLSSAAKAELRNQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGER 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1439 RKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVcDRVAIMVSGQL 1511
Cdd:PRK11629 152 QRVAIARALVNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRM-SRQLEMRDGRL 223
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
480-642 |
4.13e-13 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 73.95 E-value: 4.13e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 480 ISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfasiyghRVSeidemFEARKMIG 559
Cdd:COG0488 1 LENLSKSFGGRP----LLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSG-------EVS-----IPKGLRIG 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 560 ICPQSDINFDVLTVEENlsILASIKGIPAnnIIQEVQKVL-----LDLDMQAIKDNQAK--------------------- 613
Cdd:COG0488 65 YLPQEPPLDDDLTVLDT--VLDGDAELRA--LEAELEELEaklaePDEDLERLAELQEEfealggweaearaeeilsglg 140
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 146134400 614 -----------KLSGGQKRKLSVGIAVLGNPKILLLDEPT 642
Cdd:COG0488 141 fpeedldrpvsELSGGWRRRVALARALLSEPDLLLLDEPT 180
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
1287-1511 |
4.26e-13 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 70.96 E-value: 4.26e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1287 KPAIMVCNLHKEYDDKKdflhsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTL--VGDVEP---TSGKIFLGD 1361
Cdd:PRK14239 3 EPILQVSDLSVYYNKKK-----------ALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrMNDLNPevtITGSIVYNG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1362 YGSHSSEDD--ESIKCMGYC-PQTNPlWPdLTLQEHFeIYG-AVKGMSPgdmKEVISR-ITKAL-------DLKEHLQKT 1429
Cdd:PRK14239 72 HNIYSPRTDtvDLRKEIGMVfQQPNP-FP-MSIYENV-VYGlRLKGIKD---KQVLDEaVEKSLkgasiwdEVKDRLHDS 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1430 VKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQhmwRAIRTAFKNKKRAALLT-THYMEEAEAVCDRVAIMVS 1508
Cdd:PRK14239 146 ALGLSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAG---KIEETLLGLKDDYTMLLvTRSMQQASRISDRTGFFLD 222
|
...
gi 146134400 1509 GQL 1511
Cdd:PRK14239 223 GDL 225
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
446-671 |
5.96e-13 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 74.30 E-value: 5.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 446 NYKELSEGNINGNiSLNEIvepvssefigkEAIRISGIQKSYRKKtENVEALRNLSFDIYEGQITALLGHSGTGKSTLMN 525
Cdd:PTZ00265 363 NRKPLVENNDDGK-KLKDI-----------KKIQFKNVRFHYDTR-KDVEIYKDLNFTLTEGKTYAFVGESGCGKSTILK 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 526 ILCGLCPPSDGFASIY-GHRVSEIDEMFeARKMIGICPQSDINF---------------------------DVLTVEENL 577
Cdd:PTZ00265 430 LIERLYDPTEGDIIINdSHNLKDINLKW-WRSKIGVVSQDPLLFsnsiknnikyslyslkdlealsnyyneDGNDSQENK 508
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 578 SILASIKGIPA---NNIIQEV------------------------QKVLLDLDMQAIKD-------NQAKKLSGGQKRKL 623
Cdd:PTZ00265 509 NKRNSCRAKCAgdlNDMSNTTdsneliemrknyqtikdsevvdvsKKVLIHDFVSALPDkyetlvgSNASKLSGGQKQRI 588
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 146134400 624 SVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKA--NRVTVFSTH 671
Cdd:PTZ00265 589 SIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGneNRITIIIAH 638
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
509-705 |
7.21e-13 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 71.83 E-value: 7.21e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 509 ITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMF----EARKmIGICPQSDINFDVLTVEENLSIlasik 584
Cdd:PRK11144 26 ITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKGIclppEKRR-IGYVFQDARLFPHYKVRGNLRY----- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 585 GIPANNIIQEVQKVLLdLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMD-PCSRHivwnLLKY--RK 661
Cdd:PRK11144 100 GMAKSMVAQFDKIVAL-LGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDlPRKRE----LLPYleRL 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 146134400 662 ANRVT---VFSTHFMDEADILADRKAVISQGMLKCVGSsifLKSKWG 705
Cdd:PRK11144 175 AREINipiLYVSHSLDEILRLADRVVVLEQGKVKAFGP---LEEVWA 218
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
489-677 |
7.38e-13 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 69.04 E-value: 7.38e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 489 KKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHrvseidemfearkmIGICPQSD--I 566
Cdd:cd03250 13 GEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS--------------IAYVSQEPwiQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 567 NfdvltveenlsilASIKgipaNNII-------QEVQKVL----LDLDMQAIKD-----------NqakkLSGGQKRKLS 624
Cdd:cd03250 79 N-------------GTIR----ENILfgkpfdeERYEKVIkacaLEPDLEILPDgdlteigekgiN----LSGGQKQRIS 137
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 625 VGIAVLGNPKILLLDEPTAGMDP-CSRHIVWN-LLKYRKANRVTVFSTH---FMDEAD 677
Cdd:cd03250 138 LARAVYSDADIYLLDDPLSAVDAhVGRHIFENcILGLLLNNKTRILVTHqlqLLPHAD 195
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
1306-1528 |
7.58e-13 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 70.50 E-value: 7.58e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1306 LHSRKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDEsikcmGYCPQTNPL 1385
Cdd:PRK11248 7 LYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAER-----GVVFQNEGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1386 WPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDP 1465
Cdd:PRK11248 82 LPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDA 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1466 RAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRcigTVQHLKSKFGKGY 1528
Cdd:PRK11248 162 FTREQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSPGPGR---VVERLPLNFARRF 221
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
1301-1511 |
8.31e-13 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 71.01 E-value: 8.31e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1301 DKKDFLHSRKTT--KVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCM-- 1376
Cdd:PRK13641 6 ENVDYIYSPGTPmeKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETGNKNLKKLrk 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1377 --GYCPQtnplWPDLTLQEHFEI----YGAVK-GMSPGDMKEVISRITKALDLKEHL-QKTVKKLPAGIKRKLCFALSML 1448
Cdd:PRK13641 86 kvSLVFQ----FPEAQLFENTVLkdveFGPKNfGFSEDEAKEKALKWLKKVGLSEDLiSKSPFELSGGQMRRVAIAGVMA 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 1449 GNPQVTLLDEPSTGMDPRAKQHMWRairtAFKNKKRAA---LLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:PRK13641 162 YEPEILCLDEPAAGLDPEGRKEMMQ----LFKDYQKAGhtvILVTHNMDDVAEYADDVLVLEHGKL 223
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
478-657 |
9.21e-13 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 70.20 E-value: 9.21e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKT-----ENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMF 552
Cdd:PRK15112 5 LEVRNLSKTFRYRTgwfrrQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSY 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 553 EARK--MIGICPQSDIN--------FDV-LTVEENLSILASIKgipanNIIQEVQKVLLDLDMQAIKDNQakkLSGGQKR 621
Cdd:PRK15112 85 RSQRirMIFQDPSTSLNprqrisqiLDFpLRLNTDLEPEQREK-----QIIETLRQVGLLPDHASYYPHM---LAPGQKQ 156
|
170 180 190
....*....|....*....|....*....|....*.
gi 146134400 622 KLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLL 657
Cdd:PRK15112 157 RLGLARALILRPKVIIADEALASLDMSMRSQLINLM 192
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
489-689 |
1.02e-12 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 72.65 E-value: 1.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 489 KKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIY---------GHRVSEidemfeaRKMIG 559
Cdd:PRK13549 13 KTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHGTYEGEIIfegeelqasNIRDTE-------RAGIA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 560 ICPQSdinfdvLTVEENLSILASI-------KG--IPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVL 630
Cdd:PRK13549 86 IIHQE------LALVKELSVLENIflgneitPGgiMDYDAMYLRAQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKALN 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 631 GNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVT-VFSTHFMDEADILADRKAVISQG 689
Cdd:PRK13549 160 KQARLLILDEPTASLTESETAVLLDIIRDLKAHGIAcIYISHKLNEVKAISDTICVIRDG 219
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
480-689 |
1.03e-12 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 70.09 E-value: 1.03e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 480 ISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDE----MF-EA 554
Cdd:PRK11247 15 LNAVSKRYGERT----VLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAEAREdtrlMFqDA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 555 RkmigICPQSdinfdvlTVEENLSIlaSIKGIPANNIIQEVQKVLLdldmqaikDNQAKK----LSGGQKRKLSVGIAVL 630
Cdd:PRK11247 91 R----LLPWK-------KVIDNVGL--GLKGQWRDAALQALAAVGL--------ADRANEwpaaLSGGQKQRVALARALI 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 631 GNPKILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADILADRKAVISQG 689
Cdd:PRK11247 150 HRPGLLLLDEPLGALDALTRIEMQDLIEslWQQHGFTVLLVTHDVSEAVAMADRVLLIEEG 210
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
478-676 |
1.54e-12 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 70.50 E-value: 1.54e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTE-NVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDG-----FASIYGHRVSEIDEM 551
Cdd:PRK13651 3 IKVKNIVKIFNKKLPtELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGtiewiFKDEKNKKKTKEKEK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 552 F------------------EARKMIGICPQ-SDINFDVLTVEENLSILASIKGIPANNIIQEVQKV--LLDLDMQAIKDN 610
Cdd:PRK13651 83 VleklviqktrfkkikkikEIRRRVGVVFQfAEYQLFEQTIEKDIIFGPVSMGVSKEEAKKRAAKYieLVGLDESYLQRS 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 611 QAKkLSGGQKRKLSV-GIAVLgNPKILLLDEPTAGMDPCSRHIVWNLL-KYRKANRVTVFSTHFMDEA 676
Cdd:PRK13651 163 PFE-LSGGQKRRVALaGILAM-EPDFLVFDEPTAGLDPQGVKEILEIFdNLNKQGKTIILVTHDLDNV 228
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
509-691 |
1.98e-12 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 69.74 E-value: 1.98e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 509 ITALLGHSGTGKSTLMNILCGLCPPSDGF-----ASIYGHRVSEIDEMFEARKMIGICPQSDINFDVLTVEENLSILASI 583
Cdd:PRK14271 49 VTSLMGPTGSGKTTFLRTLNRMNDKVSGYrysgdVLLGGRSIFNYRDVLEFRRRVGMLFQRPNPFPMSIMDNVLAGVRAH 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 584 KGIPANNIIQEVQKVLLDLDM-QAIKDNQAK---KLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKy 659
Cdd:PRK14271 129 KLVPRKEFRGVAQARLTEVGLwDAVKDRLSDspfRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIR- 207
|
170 180 190
....*....|....*....|....*....|...
gi 146134400 660 RKANRVTV-FSTHFMDEADILADRKAVISQGML 691
Cdd:PRK14271 208 SLADRLTViIVTHNLAQAARISDRAALFFDGRL 240
|
|
| sufC |
TIGR01978 |
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ... |
1292-1509 |
2.17e-12 |
|
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]
Pssm-ID: 273907 [Multi-domain] Cd Length: 243 Bit Score: 68.83 E-value: 2.17e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1292 VCNLHKEYDDKKdflhsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGD--VEPTSGKIFLGDYGSHSSED 1369
Cdd:TIGR01978 3 IKDLHVSVEDKE-----------ILKGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAGHpsYEVTSGTILFKGQDLLELEP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 DE-SIKCMGYCPQTNPLWPDLTLQEHF-EIYGAV---KGMSPGDMKEVISRITKALDL----KEHLQKTVKKLPAGIKRK 1440
Cdd:TIGR01978 72 DErARAGLFLAFQYPEEIPGVSNLEFLrSALNARrsaRGEEPLDLLDFEKLLKEKLALldmdEEFLNRSVNEGFSGGEKK 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146134400 1441 LC--FALSMLgNPQVTLLDEPSTGMDPRAKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVC-DRVAIMVSG 1509
Cdd:TIGR01978 152 RNeiLQMALL-EPKLAILDEIDSGLDIDALKIVAEGIN-RLREPDRSFLIITHYQRLLNYIKpDYVHVLLDG 221
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
1306-1525 |
2.31e-12 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 72.08 E-value: 2.31e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1306 LHSRKTtkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI--FLGDYGSHSSEDDESiKCMGYCPQ-- 1381
Cdd:NF033858 9 HRYGKT--VALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVevLGGDMADARHRRAVC-PRIAYMPQgl 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1382 -TNpLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRK--LCFALsmLGNPQVTLLDE 1458
Cdd:NF033858 86 gKN-LYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKlgLCCAL--IHDPDLLILDE 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1459 PSTGMDPRAKQHMWR---AIRTAfknkkRAA---LLTTHYMEEAEAvCDRVAIMVSGQLRCIGTVQHLKSKFG 1525
Cdd:NF033858 163 PTTGVDPLSRRQFWElidRIRAE-----RPGmsvLVATAYMEEAER-FDWLVAMDAGRVLATGTPAELLARTG 229
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
1315-1564 |
2.39e-12 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 69.25 E-value: 2.39e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1315 ATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFL-----GDYgshsSEDDESIKCMGYCPQtNP--LWP 1387
Cdd:PRK13644 17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVsgidtGDF----SKLQGIRKLVGIVFQ-NPetQFV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1388 DLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRA 1467
Cdd:PRK13644 92 GRTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDS 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1468 KQHMWRAIRTaFKNKKRAALLTTHYMEEAEAVcDRVAIMVSGQLRCIGTVQHLKSKFGKGYfLEIKLKDWIENLEidRLQ 1547
Cdd:PRK13644 172 GIAVLERIKK-LHEKGKTIVYITHNLEELHDA-DRIIVMDRGKIVLEGEPENVLSDVSLQT-LGLTPPSLIELAE--NLK 246
|
250
....*....|....*...
gi 146134400 1548 R-EIQYIFPNASRQESFS 1564
Cdd:PRK13644 247 MhGVVIPWENTSSPSSFA 264
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
474-691 |
2.48e-12 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 71.21 E-value: 2.48e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 474 GKEAIRISGIqkSYRKKtENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSE--IDEM 551
Cdd:COG3845 254 GEVVLEVENL--SVRDD-RGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGlsPRER 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 552 FEA--------RKMIGICPQsdinfdvLTVEENLsILASIKGIP-ANNIIqevqkvlldLDMQAIKDN------------ 610
Cdd:COG3845 331 RRLgvayipedRLGRGLVPD-------MSVAENL-ILGRYRRPPfSRGGF---------LDRKAIRAFaeelieefdvrt 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 611 -----QAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWN-LLKYRKANR-VTVFSTHfMDEADILADRK 683
Cdd:COG3845 394 pgpdtPARSLSGGNQQKVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQrLLELRDAGAaVLLISED-LDEILALSDRI 472
|
....*...
gi 146134400 684 AVISQGML 691
Cdd:COG3845 473 AVMYEGRI 480
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
497-675 |
2.56e-12 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 68.20 E-value: 2.56e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEID-EMFeaRKMIGICPQSDINFDVlTVEE 575
Cdd:PRK10247 23 LNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKpEIY--RQQVSYCAQTPTLFGD-TVYD 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 576 NLSILASIKgipanNIIQEVQKVLLDLDMQAIKDNQAKK----LSGGQKRKlsvgIAVLGN----PKILLLDEPTAGMDP 647
Cdd:PRK10247 100 NLIFPWQIR-----NQQPDPAIFLDDLERFALPDTILTKniaeLSGGEKQR----ISLIRNlqfmPKVLLLDEITSALDE 170
|
170 180 190
....*....|....*....|....*....|
gi 146134400 648 CSRHIVWNLL-KYRKANRVTV-FSTHFMDE 675
Cdd:PRK10247 171 SNKHNVNEIIhRYVREQNIAVlWVTHDKDE 200
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
496-690 |
2.58e-12 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 68.86 E-value: 2.58e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 496 ALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQSDINFDVLTVEE 575
Cdd:PRK11300 20 AVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIARMGVVRTFQHVRLFREMTVIE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 576 NL----------SILASIKGIPA-----NNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDE 640
Cdd:PRK11300 100 NLlvaqhqqlktGLFSGLLKTPAfrraeSEALDRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILMLDE 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 146134400 641 PTAGMDPCSRHIVWNLL-KYRKANRVTVFST-HFMDEADILADRKAVISQGM 690
Cdd:PRK11300 180 PAAGLNPKETKELDELIaELRNEHNVTVLLIeHDMKLVMGISDRIYVVNQGT 231
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
497-646 |
3.03e-12 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 68.60 E-value: 3.03e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfasiyghrvsEIDEmfEARKMIGICPQSdINFDV---LTV 573
Cdd:PRK09544 20 LSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEG----------VIKR--NGKLRIGYVPQK-LYLDTtlpLTV 86
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 574 EENLSILASIKG---IPANNIIQEVQkvLLDLDMQaikdnqakKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMD 646
Cdd:PRK09544 87 NRFLRLRPGTKKediLPALKRVQAGH--LIDAPMQ--------KLSGGETQRVLLARALLNRPQLLVLDEPTQGVD 152
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
1320-1509 |
3.62e-12 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 68.76 E-value: 3.62e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1320 SFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI-FLGDYGSHSSEDDesikCMGYCPQTNPL-WP------DLTL 1391
Cdd:PRK15056 27 SFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKIsILGQPTRQALQKN----LVAYVPQSEEVdWSfpvlveDVVM 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1392 QEHFEIYGAVKGMSPGDmKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHM 1471
Cdd:PRK15056 103 MGRYGHMGWLRRAKKRD-RQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTEARI 181
|
170 180 190
....*....|....*....|....*....|....*...
gi 146134400 1472 WRAIRtAFKNKKRAALLTTHYMEEAEAVCDrVAIMVSG 1509
Cdd:PRK15056 182 ISLLR-ELRDEGKTMLVSTHNLGSVTEFCD-YTVMVKG 217
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
1319-1516 |
3.96e-12 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 68.12 E-value: 3.96e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQEHFEiY 1398
Cdd:PRK11231 21 LSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRLALLPQHHLTPEGITVRELVA-Y 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1399 gavkGMSP---------GDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQ 1469
Cdd:PRK11231 100 ----GRSPwlslwgrlsAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLDINHQV 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 146134400 1470 HMWRAIRTaFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGT 1516
Cdd:PRK11231 176 ELMRLMRE-LNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGT 221
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
499-689 |
4.10e-12 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 68.64 E-value: 4.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 499 NLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEID--EMFEARKMIGICPQSDINFDVLTVEEN 576
Cdd:PRK11831 25 NISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSrsRLYTVRKRMSMLFQSGALFTDMNVFDN 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 577 LSI-LASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWN 655
Cdd:PRK11831 105 VAYpLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDPITMGVLVK 184
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 146134400 656 LL-KYRKANRVT-VFSTH-------FMDEADILADRKaVISQG 689
Cdd:PRK11831 185 LIsELNSALGVTcVVVSHdvpevlsIADHAYIVADKK-IVAHG 226
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
1319-1519 |
4.70e-12 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 67.73 E-value: 4.70e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSE--DDESIKCM----GYCPQTNPLWPDLTLQ 1392
Cdd:PRK11124 21 ITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDFSKtpSDKAIRELrrnvGMVFQQYNLWPHLTVQ 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1393 EHF-EIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHM 1471
Cdd:PRK11124 101 QNLiEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQI 180
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 146134400 1472 WRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQH 1519
Cdd:PRK11124 181 VSIIR-ELAETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASC 227
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
497-695 |
5.49e-12 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 70.55 E-value: 5.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMfEARKMIGICPQsDIN-FDVlTVEE 575
Cdd:COG4618 348 LRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDRE-ELGRHIGYLPQ-DVElFDG-TIAE 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 576 NLSILASIkgiPANNIIQEVQKV-----LLDL----DMQaIKDNQAKkLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMD 646
Cdd:COG4618 425 NIARFGDA---DPEKVVAAAKLAgvhemILRLpdgyDTR-IGEGGAR-LSGGQRQRIGLARALYGDPRLVVLDEPNSNLD 499
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 146134400 647 PCSRHIVWNLLKYRKANRVTVF-STHfmdEADIL--ADRKAVISQGMLKCVG 695
Cdd:COG4618 500 DEGEAALAAAIRALKARGATVVvITH---RPSLLaaVDKLLVLRDGRVQAFG 548
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
493-710 |
6.11e-12 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 70.52 E-value: 6.11e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 493 NVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKmIGICPQSDINFDVlT 572
Cdd:TIGR00958 493 DVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHYLHRQ-VALVGQEPVLFSG-S 570
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 573 VEENLS----------ILASIKGIPANNIIQEVQKvlldlDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPT 642
Cdd:TIGR00958 571 VRENIAygltdtpdeeIMAAAKAANAHDFIMEFPN-----GYDTEVGEKGSQLSGGQKQRIAIARALVRKPRVLILDEAT 645
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 643 AGMDPCSRHIVWNLLKyrKANRVTVFSTHFMDEADiLADRKAVISQGMLKCVGSSIFLKSKWGIGYRL 710
Cdd:TIGR00958 646 SALDAECEQLLQESRS--RASRTVLLIAHRLSTVE-RADQILVLKKGSVVEMGTHKQLMEDQGCYKHL 710
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
1294-1525 |
7.13e-12 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 67.26 E-value: 7.13e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYDDKKDFLhsrkttkvatKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshsseDDESI 1373
Cdd:cd03253 5 NVTFAYDPGRPVL----------KDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILI---------DGQDI 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1374 ---------KCMGYCPQTNPLWPDlTLQEHFEiYGavkgmSPGDMKEVISRITKALDLKEHLQK------TV-----KKL 1433
Cdd:cd03253 66 revtldslrRAIGVVPQDTVLFND-TIGYNIR-YG-----RPDATDEEVIEAAKAAQIHDKIMRfpdgydTIvgergLKL 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1434 PAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNkkRAALLTTHYMEEAeAVCDRVAIMVSGQLRC 1513
Cdd:cd03253 139 SGGEKQRVAIARAILKNPPILLLDEATSALDTHTEREIQAALRDVSKG--RTTIVIAHRLSTI-VNADKIIVLKDGRIVE 215
|
250
....*....|..
gi 146134400 1514 IGTVQHLKSKFG 1525
Cdd:cd03253 216 RGTHEELLAKGG 227
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
467-689 |
7.36e-12 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 70.27 E-value: 7.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 467 PVSSEFIGKEAIRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYG---- 542
Cdd:PRK10261 2 PHSDELDARDVLAVENLNIAFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKmllr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 543 ---HRVSEIDEMFEAR---------KMIGICPQSDINfDVLTVEENlsILASIK---GIPANNIIQEVQKvLLDL----D 603
Cdd:PRK10261 82 rrsRQVIELSEQSAAQmrhvrgadmAMIFQEPMTSLN-PVFTVGEQ--IAESIRlhqGASREEAMVEAKR-MLDQvripE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 604 MQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKY--RKANRVTVFSTHFMDEADILAD 681
Cdd:PRK10261 158 AQTILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVlqKEMSMGVIFITHDMGVVAEIAD 237
|
....*...
gi 146134400 682 RKAVISQG 689
Cdd:PRK10261 238 RVLVMYQG 245
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
1319-1465 |
7.73e-12 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 66.96 E-value: 7.73e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYG-SHSSEDDESIKCM-----GYCPQTNPLWPDLTLQ 1392
Cdd:COG4161 21 INLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQfDFSQKPSEKAIRLlrqkvGMVFQQYNLWPHLTVM 100
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 146134400 1393 EHF-EIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDP 1465
Cdd:COG4161 101 ENLiEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDP 174
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1313-1526 |
7.85e-12 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 67.42 E-value: 7.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1313 KVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYG-SHSSEDDESiKCMGYCPQtNPLW---PD 1388
Cdd:COG1101 19 KRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDvTKLPEYKRA-KYIGRVFQ-DPMMgtaPS 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1389 LTLQEHFEI-Y--GAVKGMSPG---DMKEVISRITKALD--LKEHLQKTVKKLPAGiKRKlcfALSML----GNPQVTLL 1456
Cdd:COG1101 97 MTIEENLALaYrrGKRRGLRRGltkKRRELFRELLATLGlgLENRLDTKVGLLSGG-QRQ---ALSLLmatlTKPKLLLL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1457 DEPSTGMDPR-AKQHMwRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVaIM---------VSGQLRCIGTVQHLKSKFGK 1526
Cdd:COG1101 173 DEHTAALDPKtAALVL-ELTEKIVEENNLTTLMVTHNMEQALDYGNRL-IMmhegriildVSGEEKKKLTVEDLLELFEE 250
|
|
| ABC2_membrane_3 |
pfam12698 |
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter ... |
214-416 |
7.89e-12 |
|
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter family pfam01061.
Pssm-ID: 463674 [Multi-domain] Cd Length: 345 Bit Score: 68.57 E-value: 7.89e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 214 DTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKKLKEFLKIMGLHDTAFWLSWVLLYASLIFLMSLLMAVIATASSlFPQ 293
Cdd:pfam12698 157 SGYAYYLVGLILMIIILIGAAIIAVSIVEEKESRIKERLLVSGVSPLQYWLGKILGDFLVGLLQLLIILLLLFGIG-IPF 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 294 SSSIVIFLLFFLYGLSSVFFALMLTPLFKKSKHVGVVEFFVTVVFGFVGLLIVLIESFPRSLVWLFSPLCQCAFLIGIAQ 373
Cdd:pfam12698 236 GNLGLLLLLFLLYGLAYIALGYLLGSLFKNSEDAQSIIGIVILLLSGFFGGLFPLEDPPSFLQWIFSIIPFFSPIDGLLR 315
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 146134400 374 VmhledfnegalfsNLTEGPYPLIITIIMLALDSVFYVLLAVY 416
Cdd:pfam12698 316 L-------------IYGDSLWEIAPSLIILLLFAVVLLLLALL 345
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
1319-1518 |
8.58e-12 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 67.06 E-value: 8.58e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG--DYGSHSSEddESIKCMGYCPQTNPLWPDLTLQEHFE 1396
Cdd:COG4559 20 VSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNgrPLAAWSPW--ELARRRAVLPQHSSLAFPFTVEEVVA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1397 IYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFA--LSML-----GNPQVTLLDEPSTGMDPRAKQ 1469
Cdd:COG4559 98 LGRAPHGSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLArvLAQLwepvdGGPRWLFLDEPTSALDLAHQH 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 1470 HMWRAIRTaFKNKKRAAL-------LTTHYmeeaeavCDRVAIMVSGQLRCIGTVQ 1518
Cdd:COG4559 178 AVLRLARQ-LARRGGGVVavlhdlnLAAQY-------ADRILLLHQGRLVAQGTPE 225
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
1294-1459 |
8.70e-12 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 69.71 E-value: 8.70e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYDDKKDFLHsrkttkvatkyISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshssedDESI 1373
Cdd:COG0488 3 NLSKSFGGRPLLDD-----------VSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSI----------PKGL 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1374 KcMGYCPQTNPLWPDLTLQE-----HFEIYGAVK---------GMSPGDMKEV------------------ISRITKALD 1421
Cdd:COG0488 62 R-IGYLPQEPPLDDDLTVLDtvldgDAELRALEAeleeleaklAEPDEDLERLaelqeefealggweaearAEEILSGLG 140
|
170 180 190
....*....|....*....|....*....|....*....
gi 146134400 1422 LKEH-LQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEP 1459
Cdd:COG0488 141 FPEEdLDRPVSELSGGWRRRVALARALLSEPDLLLLDEP 179
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
1317-1516 |
9.50e-12 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 65.90 E-value: 9.50e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1317 KYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG--DYGSHSSED-DESIKCMgycPQtNPLWPDLTLQE 1393
Cdd:cd03369 25 KNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDgiDISTIPLEDlRSSLTII---PQ-DPTLFSGTIRS 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1394 HFEIYGavkgmspgdmKEVISRITKALDLKEhlqkTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWR 1473
Cdd:cd03369 101 NLDPFD----------EYSDEEIYGALRVSE----GGLNLSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQK 166
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 146134400 1474 AIRTAFKNkkrAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGT 1516
Cdd:cd03369 167 TIREEFTN---STILTIAHRLRTIIDYDKILVMDAGEVKEYDH 206
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
489-671 |
9.67e-12 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 70.32 E-value: 9.67e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 489 KKTENVEA-LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPpSDGFASIYGHRVSEIdEMFEARKMIGICPQSDIN 567
Cdd:TIGR01271 1226 KYTEAGRAvLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQIDGVSWNSV-TLQTWRKAFGVIPQKVFI 1303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 568 FDVlTVEENLSILASIKGipanniiQEVQKVLLDLDMQAIKDNQAKKL-----------SGGQKRKLSVGIAVLGNPKIL 636
Cdd:TIGR01271 1304 FSG-TFRKNLDPYEQWSD-------EEIWKVAEEVGLKSVIEQFPDKLdfvlvdggyvlSNGHKQLMCLARSILSKAKIL 1375
|
170 180 190
....*....|....*....|....*....|....*
gi 146134400 637 LLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTH 671
Cdd:TIGR01271 1376 LLDEPSAHLDPVTLQIIRKTLKQSFSNCTVILSEH 1410
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
495-691 |
9.68e-12 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 69.69 E-value: 9.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 495 EALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDE----------MFEARKMIGICPQS 564
Cdd:PRK15439 277 EGFRNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTaqrlarglvyLPEDRQSSGLYLDA 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 565 DINFDVLTVEENLSILAsIKGIPANNIIQEVQKVLldldmqAIK----DNQAKKLSGGQKRKLSVGIAVLGNPKILLLDE 640
Cdd:PRK15439 357 PLAWNVCALTHNRRGFW-IKPARENAVLERYRRAL------NIKfnhaEQAARTLSGGNQQKVLIAKCLEASPQLLIVDE 429
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 146134400 641 PTAGMDPCSRHIVWNLLKYRKANRVTV-FSTHFMDEADILADRKAVISQGML 691
Cdd:PRK15439 430 PTRGVDVSARNDIYQLIRSIAAQNVAVlFISSDLEEIEQMADRVLVMHQGEI 481
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
455-712 |
1.67e-11 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 69.62 E-value: 1.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 455 INGNISLNEIVEP-VSSEFI---------GKEAIRISGIQKSYRKKTENvEALRNLSFDIYEGQITALLGHSGTGKSTLM 524
Cdd:PLN03232 582 VNANVSLQRIEELlLSEERIlaqnpplqpGAPAISIKNGYFSWDSKTSK-PTLSDINLEIPVGSLVAIVGGTGEGKTSLI 660
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 525 NILCGLCPPSDgfasiyghrvseiDEMFEARKMIGICPQSDINFDVlTVEENLSILASIKGIPANNIIqEVQKVLLDLDM 604
Cdd:PLN03232 661 SAMLGELSHAE-------------TSSVVIRGSVAYVPQVSWIFNA-TVRENILFGSDFESERYWRAI-DVTALQHDLDL 725
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 605 QAIKD-----NQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWN-LLKYRKANRVTVFST---HFMDe 675
Cdd:PLN03232 726 LPGRDlteigERGVNISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQVFDsCMKDELKGKTRVLVTnqlHFLP- 804
|
250 260 270
....*....|....*....|....*....|....*..
gi 146134400 676 adiLADRKAVISQGMLKCVGSSIFLkSKWGIGYRLSM 712
Cdd:PLN03232 805 ---LMDRIILVSEGMIKEEGTFAEL-SKSGSLFKKLM 837
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
1323-1493 |
1.77e-11 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 69.07 E-value: 1.77e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1323 VKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIflgdygshssedDESIKcMGYCPQtnplwpdltlqehfeiYgaVK 1402
Cdd:PRK13409 362 IYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEV------------DPELK-ISYKPQ----------------Y--IK 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1403 GMSPGDMKEVISRITKALD-------------LKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQ 1469
Cdd:PRK13409 411 PDYDGTVEDLLRSITDDLGssyykseiikplqLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRL 490
|
170 180
....*....|....*....|....*.
gi 146134400 1470 HMWRAIRTAFKNKKRAALLTTH--YM 1493
Cdd:PRK13409 491 AVAKAIRRIAEEREATALVVDHdiYM 516
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
499-675 |
1.79e-11 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 68.72 E-value: 1.79e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 499 NLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPpSDGFASIYGHRVSEIDEMfEARKMI---GICPQsdinfdvL---T 572
Cdd:PRK11174 368 PLNFTLPAGQRIALVGPSGAGKTSLLNALLGFLP-YQGSLKINGIELRELDPE-SWRKHLswvGQNPQ-------LphgT 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 573 VEENLSiLASIKgipANNiiQEVQKVL-------------LDLDMQaIKDnQAKKLSGGQKRKLSVGIAVLGNPKILLLD 639
Cdd:PRK11174 439 LRDNVL-LGNPD---ASD--EQLQQALenawvseflpllpQGLDTP-IGD-QAAGLSVGQAQRLALARALLQPCQLLLLD 510
|
170 180 190
....*....|....*....|....*....|....*.
gi 146134400 640 EPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDE 675
Cdd:PRK11174 511 EPTASLDAHSEQLVMQALNAASRRQTTLMVTHQLED 546
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
497-692 |
1.90e-11 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 66.42 E-value: 1.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCpPSDGFASIYGHRVSEIdEMFEARKMIGICPQSDINFDVlTVEEN 576
Cdd:cd03289 20 LENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLL-NTEGDIQIDGVSWNSV-PLQKWRKAFGVIPQKVFIFSG-TFRKN 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 577 LSILASIKGipanniiQEVQKVLLDLDMQAIKDNQAKK-----------LSGGQKRKLSVGIAVLGNPKILLLDEPTAGM 645
Cdd:cd03289 97 LDPYGKWSD-------EEIWKVAEEVGLKSVIEQFPGQldfvlvdggcvLSHGHKQLMCLARSVLSKAKILLLDEPSAHL 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 146134400 646 DPCSRHIVWNLLKYRKANRVTVFSTHFMdEADILADRKAVISQGMLK 692
Cdd:cd03289 170 DPITYQVIRKTLKQAFADCTVILSEHRI-EAMLECQRFLVIEENKVR 215
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
1292-1516 |
2.00e-11 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 65.86 E-value: 2.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1292 VCNLHKEYDDKkDFLHSrkttkvatkyISFCVKKGEILGLLGPNGAGKSTVINTLVG--DVEPTSGKIFLgdygshsseD 1369
Cdd:COG0396 3 IKNLHVSVEGK-EILKG----------VNLTIKPGEVHAIMGPNGSGKSTLAKVLMGhpKYEVTSGSILL---------D 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 DESI----------KCMGYCPQTNPLWPDLTLqEHF--EIYGAVKG--MSPGDMKEVISRITKALDL-KEHLQKTVKklp 1434
Cdd:COG0396 63 GEDIlelspderarAGIFLAFQYPVEIPGVSV-SNFlrTALNARRGeeLSAREFLKLLKEKMKELGLdEDFLDRYVN--- 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1435 AG-----IKRKLCFALSMLgNPQVTLLDEPSTGMDPRAKQHMWRAIRtAFKNKKRAALLTTHY---MEEAEAvcDRVAIM 1506
Cdd:COG0396 139 EGfsggeKKRNEILQMLLL-EPKLAILDETDSGLDIDALRIVAEGVN-KLRSPDRGILIITHYqriLDYIKP--DFVHVL 214
|
250
....*....|
gi 146134400 1507 VSGQLRCIGT 1516
Cdd:COG0396 215 VDGRIVKSGG 224
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
1319-1516 |
2.08e-11 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 67.18 E-value: 2.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDY--GSHSSEDDESI--------------KCMGYCPQ- 1381
Cdd:PRK13631 45 ISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDIyiGDKKNNHELITnpyskkiknfkelrRRVSMVFQf 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1382 -TNPLWPDlTLQEHFeIYGAVK-GMSPGDMKEVISRITKALDLKE-HLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDE 1458
Cdd:PRK13631 125 pEYQLFKD-TIEKDI-MFGPVAlGVKKSEAKKLAKFYLNKMGLDDsYLERSPFGLSGGQKRRVAIAGILAIQPEILIFDE 202
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 1459 PSTGMDPRAKQHMWRAIRTAfKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGT 1516
Cdd:PRK13631 203 PTAGLDPKGEHEMMQLILDA-KANNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGT 259
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
478-689 |
2.35e-11 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 63.24 E-value: 2.35e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFaSIYGHRVSeidemfearkm 557
Cdd:cd03221 1 IELENLSKTYGGKL----LLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGI-VTWGSTVK----------- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQsdinfdvltveenlsilasikgipanniiqevqkvlldldmqaikdnqakkLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:cd03221 65 IGYFEQ---------------------------------------------------LSGGEKMRLALAKLLLENPNLLL 93
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 638 LDEPTAGMDPCSRHIVWNLLKYRKANRVTVfsTH---FMDEadiLADRKAVISQG 689
Cdd:cd03221 94 LDEPTNHLDLESIEALEEALKEYPGTVILV--SHdryFLDQ---VATKIIELEDG 143
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
1319-1516 |
2.96e-11 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 68.27 E-value: 2.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG-----DYgshsseDDESI-KCMGYCPQTNPLWpDLTLQ 1392
Cdd:COG1132 359 ISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDgvdirDL------TLESLrRQIGVVPQDTFLF-SGTIR 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1393 EHfeI-YGAvkgmsPG-DMKEVISRITKAldlkeHLQKTVKKLPAGI---------------KRKLCFALSMLGNPQVTL 1455
Cdd:COG1132 432 EN--IrYGR-----PDaTDEEVEEAAKAA-----QAHEFIEALPDGYdtvvgergvnlsggqRQRIAIARALLKDPPILI 499
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 1456 LDEPSTGMDPRAKQHMWRAIRTAFKNkkRAALLTTHYMEEAEAvCDRVAIMVSGQLRCIGT 1516
Cdd:COG1132 500 LDEATSALDTETEALIQEALERLMKG--RTTIVIAHRLSTIRN-ADRILVLDDGRIVEQGT 557
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
1323-1520 |
3.31e-11 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 65.32 E-value: 3.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1323 VKKGEILGLLGPNGAGKST---VINTLV---------GDVEPTSGKIFLGDYgshsSEDDESIKCMGYCPqtNPLwPDLT 1390
Cdd:PRK14247 26 IPDNTITALMGPSGSGKSTllrVFNRLIelypearvsGEVYLDGQDIFKMDV----IELRRRVQMVFQIP--NPI-PNLS 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1391 LQEHFEIyGAVKGMSPGDMKEVISRITKALD-------LKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGM 1463
Cdd:PRK14247 99 IFENVAL-GLKLNRLVKSKKELQERVRWALEkaqlwdeVKDRLDAPAGKLSGGQQQRLCIARALAFQPEVLLADEPTANL 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 1464 DPRAKQHMwRAIRTAFKnKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL 1520
Cdd:PRK14247 178 DPENTAKI-ESLFLELK-KDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREV 232
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
497-653 |
3.79e-11 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 68.33 E-value: 3.79e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGlcPPSDGFasIYGH-RVS---EIDEMFeARkMIGICPQSDINFDVLT 572
Cdd:PLN03140 896 LREVTGAFRPGVLTALMGVSGAGKTTLMDVLAG--RKTGGY--IEGDiRISgfpKKQETF-AR-ISGYCEQNDIHSPQVT 969
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 573 VEENLsILASIKGIPANNIIQE----VQKVLLDLDMQAIKDN-----QAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTA 643
Cdd:PLN03140 970 VRESL-IYSAFLRLPKEVSKEEkmmfVDEVMELVELDNLKDAivglpGVTGLSTEQRKRLTIAVELVANPSIIFMDEPTS 1048
|
170
....*....|
gi 146134400 644 GMDPCSRHIV 653
Cdd:PLN03140 1049 GLDARAAAIV 1058
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
495-646 |
4.23e-11 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 67.35 E-value: 4.23e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 495 EALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVS--EIDEMFEA--------RKMIGICPQs 564
Cdd:COG1129 266 GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRirSPRDAIRAgiayvpedRKGEGLVLD- 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 565 dinfdvLTVEENLSiLASIKGIPANNII------QEVQKVLLDLDmqaIK----DNQAKKLSGG--QKrklsvgiAVLG- 631
Cdd:COG1129 345 ------LSIRENIT-LASLDRLSRGGLLdrrrerALAEEYIKRLR---IKtpspEQPVGNLSGGnqQK-------VVLAk 407
|
170
....*....|....*....
gi 146134400 632 ----NPKILLLDEPTAGMD 646
Cdd:COG1129 408 wlatDPKVLILDEPTRGID 426
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
1319-1503 |
4.27e-11 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 64.74 E-value: 4.27e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG--DYGSHSSEddESIKCMGYCPQTNPLWPDlTLQEHFE 1396
Cdd:PRK10247 26 ISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEgeDISTLKPE--IYRQQVSYCAQTPTLFGD-TVYDNLI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1397 IYGAVKGMSPgDMKEVISRITKaLDLKEH-LQKTVKKLPAGIKRKlcfaLSMLGN----PQVTLLDEPSTGMDPRAKQHM 1471
Cdd:PRK10247 103 FPWQIRNQQP-DPAIFLDDLER-FALPDTiLTKNIAELSGGEKQR----ISLIRNlqfmPKVLLLDEITSALDESNKHNV 176
|
170 180 190
....*....|....*....|....*....|..
gi 146134400 1472 WRAIRTAFKNKKRAALLTTHYMEEAEAvCDRV 1503
Cdd:PRK10247 177 NEIIHRYVREQNIAVLWVTHDKDEINH-ADKV 207
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
503-685 |
4.74e-11 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 64.74 E-value: 4.74e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 503 DIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSeidemfearkmigICPQS-DINFDVlTVEENLSILA 581
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVS-------------YKPQYiKADYEG-TVRDLLSSIT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 582 SIKGIPA---NNIIQEVQkvlldldMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLK 658
Cdd:cd03237 87 KDFYTHPyfkTEIAKPLQ-------IEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIR 159
|
170 180
....*....|....*....|....*....
gi 146134400 659 -YRKANRVTVFST-HFMDEADILADRKAV 685
Cdd:cd03237 160 rFAENNEKTAFVVeHDIIMIDYLADRLIV 188
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
1309-1529 |
4.83e-11 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 67.38 E-value: 4.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1309 RKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEP---TSGKIFLgdyGSHSSEDDESIKCMGYCPQTNPL 1385
Cdd:TIGR00955 34 ERPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKgvkGSGSVLL---NGMPIDAKEMRAISAYVQQDDLF 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1386 WPDLTLQEHFEIYGAVKgmspgdMKEVISRITKALDLKEHLQKT---------------VKKLPAGIKRKLCFALSMLGN 1450
Cdd:TIGR00955 111 IPTLTVREHLMFQAHLR------MPRRVTKKEKRERVDEVLQALglrkcantrigvpgrVKGLSGGERKRLAFASELLTD 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1451 PQVTLLDEPSTGMDPRAKQHMWRAIRtAFKNKKRAALLTTHyMEEAEAVC--DRVAIMVSGQLRCIGTVQHLKSKFGKGY 1528
Cdd:TIGR00955 185 PPLLFCDEPTSGLDSFMAYSVVQVLK-GLAQKGKTIICTIH-QPSSELFElfDKIILMAEGRVAYLGSPDQAVPFFSDLG 262
|
.
gi 146134400 1529 F 1529
Cdd:TIGR00955 263 H 263
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
501-689 |
6.50e-11 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 64.22 E-value: 6.50e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 501 SFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYG--HRVSEIdemfeARKMIGICPQSDINFDVLTVEENLS 578
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGqdHTTTPP-----SRRPVSMLFQENNLFSHLTVAQNIG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 579 IlasikGIPANNIIQEVQKVLLdldmQAIKDNQA---------KKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCS 649
Cdd:PRK10771 94 L-----GLNPGLKLNAAQREKL----HAIARQMGiedllarlpGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPAL 164
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 146134400 650 RHIVWNLLKYRKANR-VTVFS-THFMDEADILADRKAVISQG 689
Cdd:PRK10771 165 RQEMLTLVSQVCQERqLTLLMvSHSLEDAARIAPRSLVVADG 206
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
1317-1540 |
8.82e-11 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 64.28 E-value: 8.82e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1317 KYISFCVKKGEILGLLGPNGAGKSTVINTLVG--DVEPTSGKIFLgdygshsseDDESIkcmgycpqtNPLWPD------ 1388
Cdd:CHL00131 24 KGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGhpAYKILEGDILF---------KGESI---------LDLEPEerahlg 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1389 --LTLQEHFEIYGA------------------VKGMSPGDMKEVISRITKALDLKEH-LQKTVKKLPAGIKRKLCFALSM 1447
Cdd:CHL00131 86 ifLAFQYPIEIPGVsnadflrlaynskrkfqgLPELDPLEFLEIINEKLKLVGMDPSfLSRNVNEGFSGGEKKRNEILQM 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1448 -LGNPQVTLLDEPSTGMDPRAKQHMWRAIRTaFKNKKRAALLTTHYMEEAEAVC-DRVAIMVSGQLRCIGTVQHLKSkfg 1525
Cdd:CHL00131 166 aLLDSELAILDETDSGLDIDALKIIAEGINK-LMTSENSIILITHYQRLLDYIKpDYVHVMQNGKIIKTGDAELAKE--- 241
|
250
....*....|....*
gi 146134400 1526 kgyfLEIKLKDWIEN 1540
Cdd:CHL00131 242 ----LEKKGYDWLKQ 252
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
1319-1518 |
9.44e-11 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 64.39 E-value: 9.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQtNPLWPDLTLQEHFEI- 1397
Cdd:PRK13648 28 VSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKHIGIVFQ-NPDNQFVGSIVKYDVa 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1398 YGAVKGMSPGD-MKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIR 1476
Cdd:PRK13648 107 FGLENHAVPYDeMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVR 186
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 146134400 1477 TAFKNKKRAALLTTHYMEEAeAVCDRVAIMVSGQLRCIGTVQ 1518
Cdd:PRK13648 187 KVKSEHNITIISITHDLSEA-MEADHVIVMNKGTVYKEGTPT 227
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
497-646 |
9.62e-11 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 66.38 E-value: 9.62e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEmfEA-RKMIGICPQsdinfDvlTVEE 575
Cdd:COG5265 374 LKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQ--ASlRAAIGIVPQ-----D--TVLF 444
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 576 NLSIlasikgipANNII--------QEVQKVLldlDMQAIKDNQAK--------------KLSGGQKRKlsVGIA--VLG 631
Cdd:COG5265 445 NDTI--------AYNIAygrpdaseEEVEAAA---RAAQIHDFIESlpdgydtrvgerglKLSGGEKQR--VAIArtLLK 511
|
170
....*....|....*
gi 146134400 632 NPKILLLDEPTAGMD 646
Cdd:COG5265 512 NPPILIFDEATSALD 526
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
1303-1557 |
1.03e-10 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 64.26 E-value: 1.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1303 KDFLHSRkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTL----VGDVEPTSGKIFLGDY----GSHSSEDDESIK 1374
Cdd:PRK09984 12 KTFNQHQ-----ALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLsgliTGDKSAGSHIELLGRTvqreGRLARDIRKSRA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1375 CMGYCPQTNPLWPDLTLQEHFEIyGA----------VKGMSPGDMKEVISRITKaLDLKEHLQKTVKKLPAGIKRKLCFA 1444
Cdd:PRK09984 87 NTGYIFQQFNLVNRLSVLENVLI-GAlgstpfwrtcFSWFTREQKQRALQALTR-VGMVHFAHQRVSTLSGGQQQRVAIA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1445 LSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLkskf 1524
Cdd:PRK09984 165 RALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQF---- 240
|
250 260 270
....*....|....*....|....*....|...
gi 146134400 1525 gkgyfleiklkdwiENLEIDRLQREIQYIFPNA 1557
Cdd:PRK09984 241 --------------DNERFDHLYRSINRVEENA 259
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
1319-1491 |
1.24e-10 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 62.66 E-value: 1.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdYGSHSSEDDESI-KCMGYCPQTNPLWPDLTLQEH--F 1395
Cdd:PRK13540 20 ISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILF--ERQSIKKDLCTYqKQLCFVGHRSGINPYLTLRENclY 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1396 EIYgavkgMSPGDMKevISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAI 1475
Cdd:PRK13540 98 DIH-----FSPGAVG--ITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTIITKI 170
|
170
....*....|....*.
gi 146134400 1476 RtAFKNKKRAALLTTH 1491
Cdd:PRK13540 171 Q-EHRAKGGAVLLTSH 185
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
1288-1512 |
1.27e-10 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 63.90 E-value: 1.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1288 PAIMVCNLHKEYDDKKdflhsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVI------NTLVGDVEpTSGKI-FLG 1360
Cdd:PRK14258 6 PAIKVNNLSFYYDTQK-----------ILEGVSMEIYQSKVTAIIGPSGCGKSTFLkclnrmNELESEVR-VEGRVeFFN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1361 D--YGSHSSEDDESIKCMGYCPQTNpLWPdLTLQEHFEIYGAVKGMSPG-DMKEVISRITKALDL----KEHLQKTVKKL 1433
Cdd:PRK14258 74 QniYERRVNLNRLRRQVSMVHPKPN-LFP-MSVYDNVAYGVKIVGWRPKlEIDDIVESALKDADLwdeiKHKIHKSALDL 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 1434 PAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLR 1512
Cdd:PRK14258 152 SGGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGNENR 230
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
497-646 |
1.29e-10 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 65.80 E-value: 1.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSE----------IDEMFEARKMIGIcpqsdi 566
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTrspqdglangIVYISEDRKRDGL------ 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 567 nfdVL--TVEENLSILA----SIKGIPANNIiQEVQKVLLDLDMQAIK----DNQAKKLSGGQKRKLSVGIAVLGNPKIL 636
Cdd:PRK10762 342 ---VLgmSVKENMSLTAlryfSRAGGSLKHA-DEQQAVSDFIRLFNIKtpsmEQAIGLLSGGNQQKVAIARGLMTRPKVL 417
|
170
....*....|
gi 146134400 637 LLDEPTAGMD 646
Cdd:PRK10762 418 ILDEPTRGVD 427
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
507-671 |
1.42e-10 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 66.06 E-value: 1.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 507 GQITALLGHSGTGKSTLMNILCGLCPPSD--GFASIYGHRVSEidemfEARKMIGICPQSDINFDVLTVEENL------- 577
Cdd:PLN03211 94 GEILAVLGPSGSGKSTLLNALAGRIQGNNftGTILANNRKPTK-----QILKRTGFVTQDDILYPHLTVRETLvfcsllr 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 578 ---SILASIKGIPANNIIQEVQkvLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRH-IV 653
Cdd:PLN03211 169 lpkSLTKQEKILVAESVISELG--LTKCENTIIGNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYrLV 246
|
170
....*....|....*...
gi 146134400 654 WNLLKYRKANRVTVFSTH 671
Cdd:PLN03211 247 LTLGSLAQKGKTIVTSMH 264
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
1323-1491 |
1.53e-10 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 63.54 E-value: 1.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1323 VKKGEILGLLGPNGAGKSTVINTLVGDVEPTsgkifLGDYGSHSSEDD--------------ESIKCMGYCPQTNPLWPD 1388
Cdd:cd03236 23 PREGQVLGLVGPNGIGKSTALKILAGKLKPN-----LGKFDDPPDWDEildefrgselqnyfTKLLEGDVKVIVKPQYVD 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1389 LtlqehfeIYGAVKG-----MSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGM 1463
Cdd:cd03236 98 L-------IPKAVKGkvgelLKKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYL 170
|
170 180
....*....|....*....|....*...
gi 146134400 1464 DPRAKQHMWRAIRTAFKNkKRAALLTTH 1491
Cdd:cd03236 171 DIKQRLNAARLIRELAED-DNYVLVVEH 197
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
496-646 |
1.58e-10 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 65.75 E-value: 1.58e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 496 ALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDeMFEARKMIGICPQSDINFDvLTVEE 575
Cdd:PRK13657 350 GVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVT-RASLRRNIAVVFQDAGLFN-RSIED 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 576 NLSI----------LASIKGIPANNIIqevQKVLLDLDMQAikDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGM 645
Cdd:PRK13657 428 NIRVgrpdatdeemRAAAERAQAHDFI---ERKPDGYDTVV--GERGRQLSGGERQRLAIARALLKDPPILILDEATSAL 502
|
.
gi 146134400 646 D 646
Cdd:PRK13657 503 D 503
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1319-1511 |
1.60e-10 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 62.97 E-value: 1.60e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI-FLGDYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQEHFEI 1397
Cdd:PRK11614 24 VSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIvFDGKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEENLAM 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1398 YGAVkgmspGDMKEVISRITKALDLKEHLQ----KTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWR 1473
Cdd:PRK11614 104 GGFF-----AERDQFQERIKWVYELFPRLHerriQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAPIIIQQIFD 178
|
170 180 190
....*....|....*....|....*....|....*...
gi 146134400 1474 AIRTaFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:PRK11614 179 TIEQ-LREQGMTIFLVEQNANQALKLADRGYVLENGHV 215
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
488-692 |
1.85e-10 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 63.45 E-value: 1.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 488 RKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGH------------RVSEIDEMFEAR 555
Cdd:PRK10619 12 HKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQtinlvrdkdgqlKVADKNQLRLLR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 556 KMIGICPQSDINFDVLTVEEN-----LSILASIKGIPANNIIQEVQKVLLDldmQAIKDNQAKKLSGGQKRKLSVGIAVL 630
Cdd:PRK10619 92 TRLTMVFQHFNLWSHMTVLENvmeapIQVLGLSKQEARERAVKYLAKVGID---ERAQGKYPVHLSGGQQQRVSIARALA 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 631 GNPKILLLDEPTAGMDPcsrHIVWNLL----KYRKANRVTVFSTHFMDEADILADRKAVISQGMLK 692
Cdd:PRK10619 169 MEPEVLLFDEPTSALDP---ELVGEVLrimqQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIE 231
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
1323-1512 |
1.89e-10 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 62.87 E-value: 1.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1323 VKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdYGSHSSEDDES------IKCMGYCPQTNPLWPDLTLQEHFE 1396
Cdd:PRK10584 33 VKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSL--VGQPLHQMDEEaraklrAKHVGFVFQSFMLIPTLNALENVE 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1397 IYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDpraKQHMWRAIR 1476
Cdd:PRK10584 111 LPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLD---RQTGDKIAD 187
|
170 180 190
....*....|....*....|....*....|....*....
gi 146134400 1477 TAFKNKKRAA---LLTTHYMEEAeAVCDRVAIMVSGQLR 1512
Cdd:PRK10584 188 LLFSLNREHGttlILVTHDLQLA-ARCDRRLRLVNGQLQ 225
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
497-646 |
2.04e-10 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 63.27 E-value: 2.04e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKmIGICPQSDINFDVLTVEEn 576
Cdd:PRK10575 27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARK-VAYLPQQLPAAEGMTVRE- 104
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 577 lsiLASIKGIPANNII--------QEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMD 646
Cdd:PRK10575 105 ---LVAIGRYPWHGALgrfgaadrEKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALD 179
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
492-696 |
2.10e-10 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 61.77 E-value: 2.10e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 492 ENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGlCP---PSDGfaSIY--GHRVSEIdEMFE-ARKMIGICPQSD 565
Cdd:cd03217 11 GGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMG-HPkyeVTEG--EILfkGEDITDL-PPEErARLGIFLAFQYP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 566 INFDVLTVEEnlsilasikgipanniiqevqkVLLDLDMqaikdnqakKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGM 645
Cdd:cd03217 87 PEIPGVKNAD----------------------FLRYVNE---------GFSGGEKKRNEILQLLLLEPDLAILDEPDSGL 135
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 146134400 646 DPCSRHIVWNLL-KYRKANRVTVFSTHFMDEAD-ILADRKAVISQGMLKCVGS 696
Cdd:cd03217 136 DIDALRLVAEVInKLREEGKSVLIITHYQRLLDyIKPDRVHVLYDGRIVKSGD 188
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
498-691 |
2.13e-10 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 65.19 E-value: 2.13e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 498 RNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQSDIN---FDVLTVE 574
Cdd:PRK09700 280 RDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLDAVKKGMAYITESRRDngfFPNFSIA 359
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 575 ENLSILASIK--------GIPANNI---IQEVQKVLLDLDMQAIKDNqAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTA 643
Cdd:PRK09700 360 QNMAISRSLKdggykgamGLFHEVDeqrTAENQRELLALKCHSVNQN-ITELSGGNQQKVLISKWLCCCPEVIIFDEPTR 438
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 146134400 644 GMDPCSRHIVWNLL-KYRKANRVTVFSTHFMDEADILADRKAVISQGML 691
Cdd:PRK09700 439 GIDVGAKAEIYKVMrQLADDGKVILMVSSELPEIITVCDRIAVFCEGRL 487
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
478-646 |
2.15e-10 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 62.04 E-value: 2.15e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTENVeaLRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDeMFEARKM 557
Cdd:cd03369 7 IEVENLSVRYAPDLPPV--LKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIP-LEDLRSS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICPQSDINFDVlTVEENLSILasikgipanNIIQEVQkVLLDLDMQAIKDNqakkLSGGQKRKLSVGIAVLGNPKILL 637
Cdd:cd03369 84 LTIIPQDPTLFSG-TIRSNLDPF---------DEYSDEE-IYGALRVSEGGLN----LSQGQRQLLCLARALLKRPRVLV 148
|
....*....
gi 146134400 638 LDEPTAGMD 646
Cdd:cd03369 149 LDEATASID 157
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
473-692 |
2.18e-10 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 65.23 E-value: 2.18e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 473 IGKEAIRISGIQ-----KSYRKKTENVealrnlSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPS-DGFASIYGHRV- 545
Cdd:TIGR02633 253 IGDVILEARNLTcwdviNPHRKRVDDV------SFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKfEGNVFINGKPVd 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 546 ---------SEIDEMFEARKMIGICPQsdinfdvLTVEEN--LSILASIKGIPANNIIQEVQKVLLDLDMQAIK----DN 610
Cdd:TIGR02633 327 irnpaqairAGIAMVPEDRKRHGIVPI-------LGVGKNitLSVLKSFCFKMRIDAAAELQIIGSAIQRLKVKtaspFL 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 611 QAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKY--RKANRVTVFSTHfMDEADILADRKAVISQ 688
Cdd:TIGR02633 400 PIGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQlaQEGVAIIVVSSE-LAEVLGLSDRVLVIGE 478
|
....
gi 146134400 689 GMLK 692
Cdd:TIGR02633 479 GKLK 482
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
1319-1491 |
2.19e-10 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 62.13 E-value: 2.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMgYCPQTNPLWPDLTLQEHFEIY 1398
Cdd:cd03231 19 LSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSIARGLL-YLGHAPGIKTTLSVLENLRFW 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1399 GAVKGMspgdmkeviSRITKALDLK-----EHLqkTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMD----PRAKQ 1469
Cdd:cd03231 98 HADHSD---------EQVEEALARVglngfEDR--PVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDkagvARFAE 166
|
170 180
....*....|....*....|..
gi 146134400 1470 HMwrAIRTAfknKKRAALLTTH 1491
Cdd:cd03231 167 AM--AGHCA---RGGMVVLTTH 183
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
1294-1550 |
2.58e-10 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 64.28 E-value: 2.58e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYDDKkdflhsrkttkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDygSHSSEDDESI 1373
Cdd:PRK11000 8 NVTKAYGDV-----------VISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGE--KRMNDVPPAE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1374 KCMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQV 1453
Cdd:PRK11000 75 RGVGMVFQSYALYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSV 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1454 TLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL----KSKFGKGY- 1528
Cdd:PRK11000 155 FLLDEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELyhypANRFVAGFi 234
|
250 260
....*....|....*....|....*...
gi 146134400 1529 ------FLEIKlkdwIENLEIDRLQREI 1550
Cdd:PRK11000 235 gspkmnFLPVK----VTATAIEQVQVEL 258
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
458-695 |
3.05e-10 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 62.91 E-value: 3.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 458 NISLNeiVEPVSSEF----IGKEAIRISGIQKsyrKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPP 533
Cdd:PRK13546 2 NVSVN--IKNVTKEYriyrTNKERMKDALIPK---HKNKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 534 SDGFASIYGH-RVSEIDEMFEARkmigicpqsdinfdvLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQA 612
Cdd:PRK13546 77 TVGKVDRNGEvSVIAISAGLSGQ---------------LTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPV 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 613 KKLSGGQKRKLSVGIAVLGNPKILLLDEP-TAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGML 691
Cdd:PRK13546 142 KKYSSGMRAKLGFSINITVNPDILVIDEAlSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKL 221
|
....
gi 146134400 692 KCVG 695
Cdd:PRK13546 222 KDYG 225
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
477-646 |
4.38e-10 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 64.35 E-value: 4.38e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKtENVeaLRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFeARK 556
Cdd:PRK10790 340 RIDIDNVSFAYRDD-NLV--LQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSV-LRQ 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQ-----SDINFDVLTVEENLSilasikgipANNIIQEVQKVLLDLDMQAIKD-------NQAKKLSGGQKRKLS 624
Cdd:PRK10790 416 GVAMVQQdpvvlADTFLANVTLGRDIS---------EEQVWQALETVQLAELARSLPDglytplgEQGNNLSVGQKQLLA 486
|
170 180
....*....|....*....|..
gi 146134400 625 VGIAVLGNPKILLLDEPTAGMD 646
Cdd:PRK10790 487 LARVLVQTPQILILDEATANID 508
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
1290-1517 |
4.44e-10 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 63.28 E-value: 4.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKKDFLHsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshsseD 1369
Cdd:PRK11153 2 IELKNISKVFPQGGRTIH-------ALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLV---------D 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 DESIKCMGYcpqtnplwPDLTLQ--------EHFE------IYGAV------KGMSPGDMKeviSRITKALDLKEhLQKT 1429
Cdd:PRK11153 66 GQDLTALSE--------KELRKArrqigmifQHFNllssrtVFDNValplelAGTPKAEIK---ARVTELLELVG-LSDK 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1430 VKKLPA----------GIKRklcfALSMlgNPQVTLLDEPSTGMDPRAKqhmwRAIRTAFKNKKR----AALLTTHYMEE 1495
Cdd:PRK11153 134 ADRYPAqlsggqkqrvAIAR----ALAS--NPKVLLCDEATSALDPATT----RSILELLKDINRelglTIVLITHEMDV 203
|
250 260
....*....|....*....|..
gi 146134400 1496 AEAVCDRVAIMVSGQLRCIGTV 1517
Cdd:PRK11153 204 VKRICDRVAVIDAGRLVEQGTV 225
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
1319-1499 |
6.34e-10 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 60.96 E-value: 6.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEP---TSGKIFLgdygshsseDDESIKC-------MGYCPQTNPLWPD 1388
Cdd:COG4136 20 LSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPafsASGEVLL---------NGRRLTAlpaeqrrIGILFQDDLLFPH 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1389 LTLQEH--FEIYGAVKGmspgdmKEVISRITKALD---LKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGM 1463
Cdd:COG4136 91 LSVGENlaFALPPTIGR------AQRRARVEQALEeagLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKL 164
|
170 180 190
....*....|....*....|....*....|....*.
gi 146134400 1464 DPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAV 1499
Cdd:COG4136 165 DAALRAQFREFVFEQIRQRGIPALLVTHDEEDAPAA 200
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
1319-1510 |
6.47e-10 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 60.56 E-value: 6.47e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGdyGShsseddesikcMGYCPQTnPLWPDLTLQEHFeIY 1398
Cdd:cd03250 24 INLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVP--GS-----------IAYVSQE-PWIQNGTIRENI-LF 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1399 GavkgmSPGDM---KEVIsritKALdlkeHLQKTVKKLPAGI---------------KRKLCFALSMLGNPQVTLLDEPS 1460
Cdd:cd03250 89 G-----KPFDEeryEKVI----KAC----ALEPDLEILPDGDlteigekginlsggqKQRISLARAVYSDADIYLLDDPL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 146134400 1461 TGMDPRAKQHMW-RAIRTAFKNKKrAALLTTHYMEEAEAvCDRVAIMVSGQ 1510
Cdd:cd03250 156 SAVDAHVGRHIFeNCILGLLLNNK-TRILVTHQLQLLPH-ADQIVVLDNGR 204
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
1290-1464 |
6.64e-10 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 63.80 E-value: 6.64e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKkdflhsrkttkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGdygshssed 1369
Cdd:TIGR03719 323 IEAENLTKAFGDK-----------LLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIG--------- 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 dESIKcMGYCPQT-NPLWPDLTLQEhfEIYGAVKGMSPGDmKEVISRIT------KALDLkehlQKTVKKLPAGIKRKLC 1442
Cdd:TIGR03719 383 -ETVK-LAYVDQSrDALDPNKTVWE--EISGGLDIIKLGK-REIPSRAYvgrfnfKGSDQ----QKKVGQLSGGERNRVH 453
|
170 180
....*....|....*....|..
gi 146134400 1443 FALSMLGNPQVTLLDEPSTGMD 1464
Cdd:TIGR03719 454 LAKTLKSGGNVLLLDEPTNDLD 475
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
1314-1504 |
6.97e-10 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 61.72 E-value: 6.97e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1314 VATKYISFCVKKGEILGLLGPNGAGKSTVINTL--VGDVEPT---SGKIFLGDYGSHSSEDD--ESIKCMGYCPQT-NPl 1385
Cdd:PRK14243 24 LAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFnrLNDLIPGfrvEGKVTFHGKNLYAPDVDpvEVRRRIGMVFQKpNP- 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1386 WPDlTLQEHFEiYGA-VKGMSpGDMKEVISRITK--AL--DLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPS 1460
Cdd:PRK14243 103 FPK-SIYDNIA-YGArINGYK-GDMDELVERSLRqaALwdEVKDKLKQSGLSLSGGQQQRLCIARAIAVQPEVILMDEPC 179
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 146134400 1461 TGMDPRAKqhmwRAIRTAFKNKKR--AALLTTHYMEEAEAVCDRVA 1504
Cdd:PRK14243 180 SALDPIST----LRIEELMHELKEqyTIIIVTHNMQQAARVSDMTA 221
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
1319-1529 |
8.02e-10 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 64.23 E-value: 8.02e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQTNPLWPDLT------LQ 1392
Cdd:PLN03232 1255 LSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTDLRRVLSIIPQSPVLFSGTVrfnidpFS 1334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1393 EHFEIyGAVKGMSPGDMKEVISRITKALDLKehLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMW 1472
Cdd:PLN03232 1335 EHNDA-DLWEALERAHIKDVIDRNPFGLDAE--VSEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDVRTDSLIQ 1411
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 1473 RAIRTAFKNkkrAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGYF 1529
Cdd:PLN03232 1412 RTIREEFKS---CTMLVIAHRLNTIIDCDKILVLSSGQVLEYDSPQELLSRDTSAFF 1465
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
1323-1510 |
8.36e-10 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 59.51 E-value: 8.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1323 VKKGEILGLLGPNGAGKSTVINTLVGDVEPTsgkiflgdygshsSEDDEsikcmgycpqtnplWPDLTLqehfeiygAVK 1402
Cdd:cd03222 22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPN-------------GDNDE--------------WDGITP--------VYK 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1403 GmspgdmkevisritkaldlkehlQKTvkKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNK 1482
Cdd:cd03222 67 P-----------------------QYI--DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEG 121
|
170 180
....*....|....*....|....*...
gi 146134400 1483 KRAALLTTHYMEEAEAVCDRVaIMVSGQ 1510
Cdd:cd03222 122 KKTALVVEHDLAVLDYLSDRI-HVFEGE 148
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
1319-1526 |
9.29e-10 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 60.71 E-value: 9.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG-----DYGSHSSEddesiKCMGYCPQTNPLWPDlTLQE 1393
Cdd:cd03251 21 ISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDghdvrDYTLASLR-----RQIGLVSQDVFLFND-TVAE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1394 HFEiYGAvkgmsPG-DMKEVIS--RITKALDLKEHLQK---TV-----KKLPAGIKRKLCFALSMLGNPQVTLLDEPSTG 1462
Cdd:cd03251 95 NIA-YGR-----PGaTREEVEEaaRAANAHEFIMELPEgydTVigergVKLSGGQRQRIAIARALLKDPPILILDEATSA 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 146134400 1463 MDPRAKQHMWRAIRTAFKNkkRAALLTTHYMEEAEAVcDRVAIMVSGQLRCIGTVQHLKSKFGK 1526
Cdd:cd03251 169 LDTESERLVQAALERLMKN--RTTFVIAHRLSTIENA-DRIVVLEDGKIVERGTHEELLAQGGV 229
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
488-640 |
1.02e-09 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 62.99 E-value: 1.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 488 RKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGhrvseidemfeARKMIGIcpQSDIN 567
Cdd:PRK13545 31 SKDGEYHYALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKG-----------SAALIAI--SSGLN 97
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 568 fDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDE 640
Cdd:PRK13545 98 -GQLTGIENIELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDE 169
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
479-689 |
1.09e-09 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 61.10 E-value: 1.09e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 479 RISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASiYGHR---VSEIDEMFEA- 554
Cdd:PRK11701 8 SVRGLTKLY----GPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVH-YRMRdgqLRDLYALSEAe 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 555 RKMIGicpQSDINFdvltVEEN--------LSILASI----KGIPAN---NIIQE----VQKVLLDLDMQaikDNQAKKL 615
Cdd:PRK11701 83 RRRLL---RTEWGF----VHQHprdglrmqVSAGGNIgerlMAVGARhygDIRATagdwLERVEIDAARI---DDLPTTF 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 616 SGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADILADRKAVISQG 689
Cdd:PRK11701 153 SGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRglVRELGLAVVIVTHDLAVARLLAHRLLVMKQG 228
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
1319-1476 |
1.14e-09 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 59.56 E-value: 1.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTL-----VGDVEptsGKIFLGDYgshssEDDESI-KCMGYCPQTNPLWPDLTLQ 1392
Cdd:cd03232 26 ISGYVKPGTLTALMGESGAGKTTLLDVLagrktAGVIT---GEILINGR-----PLDKNFqRSTGYVEQQDVHSPNLTVR 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1393 EHFEIYGAVKGMSPGDmkevisritkaldlkehlqktvkklpagiKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMW 1472
Cdd:cd03232 98 EALRFSALLRGLSVEQ-----------------------------RKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIV 148
|
....
gi 146134400 1473 RAIR 1476
Cdd:cd03232 149 RFLK 152
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
1294-1511 |
1.18e-09 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 62.02 E-value: 1.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYddkkdflHSRKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYgshsseddesi 1373
Cdd:COG1135 6 NLSKTF-------PTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGV----------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1374 kcmgycpqtnplwpDLT------LQE----------HFE------IYGAV------KGMSPGDMKEvisRITKALDL--- 1422
Cdd:COG1135 68 --------------DLTalsereLRAarrkigmifqHFNllssrtVAENValpleiAGVPKAEIRK---RVAELLELvgl 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1423 --KEHlqktvkKLPA----------GIKRklcfALSMlgNPQVTLLDEPSTGMDPRAKQhmwrAIRTAFK--NKKRAA-- 1486
Cdd:COG1135 131 sdKAD------AYPSqlsggqkqrvGIAR----ALAN--NPKVLLCDEATSALDPETTR----SILDLLKdiNRELGLti 194
|
250 260
....*....|....*....|....*
gi 146134400 1487 LLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:COG1135 195 VLITHEMDVVRRICDRVAVLENGRI 219
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
1323-1506 |
1.20e-09 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 59.55 E-value: 1.20e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1323 VKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGD-----YGSHSSEDDESIKC-------MGycpqtnpLWPDLt 1390
Cdd:NF040873 15 IPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGgarvaYVPQRSEVPDSLPLtvrdlvaMG-------RWARR- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1391 lqehfeiyGAVKGMSPGDmKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQH 1470
Cdd:NF040873 87 --------GLWRRLTRDD-RAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAESRER 157
|
170 180 190
....*....|....*....|....*....|....*.
gi 146134400 1471 MWRAIRtAFKNKKRAALLTTHYMEEAEAVcDRVAIM 1506
Cdd:NF040873 158 IIALLA-EEHARGATVVVVTHDLELVRRA-DPCVLL 191
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
1260-1482 |
1.26e-09 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 62.90 E-value: 1.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1260 INEDEDEDVKAERLKVkelmGCQCCEEK-P--AIMVCNLHKEYDDkkDFLHSRKTTkvatkyiSF------CVKKGEILG 1330
Cdd:PRK13409 37 IDEDDGKPVISEELCI----GCGICVKKcPfdAISIVNLPEELEE--EPVHRYGVN-------GFklyglpIPKEGKVTG 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1331 LLGPNGAGKSTVINTLVGDVEPTsgkifLGDYGSHSSEdDESIKcmgYCPQTnplwpdlTLQEHFE-------------- 1396
Cdd:PRK13409 104 ILGPNGIGKTTAVKILSGELIPN-----LGDYEEEPSW-DEVLK---RFRGT-------ELQNYFKklyngeikvvhkpq 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1397 ----IYGAVKG-----MSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRA 1467
Cdd:PRK13409 168 yvdlIPKVFKGkvrelLKKVDERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLDIRQ 247
|
250
....*....|....*
gi 146134400 1468 KQHMWRAIRTAFKNK 1482
Cdd:PRK13409 248 RLNVARLIRELAEGK 262
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
478-683 |
1.77e-09 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 60.47 E-value: 1.77e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYR-----KKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEmf 552
Cdd:PRK10419 4 LNVSGLSHHYAhgglsGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNR-- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 553 EARKMIgicpQSDINfdvLTVEENLSILASIKGIPAnnIIQEVQKVLLDLDMQA-----------------IKDNQAKKL 615
Cdd:PRK10419 82 AQRKAF----RRDIQ---MVFQDSISAVNPRKTVRE--IIREPLRHLLSLDKAErlarasemlravdlddsVLDKRPPQL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 616 SGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVT--VFSTH-------------FMDEADILA 680
Cdd:PRK10419 153 SGGQLQRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTacLFITHdlrlverfcqrvmVMDNGQIVE 232
|
...
gi 146134400 681 DRK 683
Cdd:PRK10419 233 TQP 235
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
485-689 |
1.95e-09 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 60.11 E-value: 1.95e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 485 KSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRV--SEIDEMfEARKMIGICP 562
Cdd:PRK09493 5 KNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVndPKVDER-LIRQEAGMVF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 563 QSDINFDVLTVEENLSI-LASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEP 641
Cdd:PRK09493 84 QQFYLFPHLTALENVMFgPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEP 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 146134400 642 TAGMDPCSRHIVWNLLKYRKANRVT-VFSTHFMDEADILADRKAVISQG 689
Cdd:PRK09493 164 TSALDPELRHEVLKVMQDLAEEGMTmVIVTHEIGFAEKVASRLIFIDKG 212
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
467-653 |
2.19e-09 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 62.56 E-value: 2.19e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 467 PVSSEFIGKEAIRISGIQKSYRKKtenVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPS---DGFASIYGH 543
Cdd:PLN03140 154 PNAARNIAESALGMLGINLAKKTK---LTILKDASGIIKPSRMTLLLGPPSSGKTTLLLALAGKLDPSlkvSGEITYNGY 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 544 RVSEidemFEARKMIGICPQSDINFDVLTVEENLSILASIKGIPA----------------------------------- 588
Cdd:PLN03140 231 RLNE----FVPRKTSAYISQNDVHVGVMTVKETLDFSARCQGVGTrydllselarrekdagifpeaevdlfmkatamegv 306
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 589 -NNIIQEVQKVLLDLDM---QAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDP--------CSRHIV 653
Cdd:PLN03140 307 kSSLITDYTLKILGLDIckdTIVGDEMIRGISGGQKKRVTTGEMIVGPTKTLFMDEISTGLDSsttyqivkCLQQIV 383
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
1319-1529 |
2.40e-09 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 62.15 E-value: 2.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQTNPLWPDlTLQEHFEIy 1398
Cdd:PRK11160 359 LSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAALRQAISVVSQRVHLFSA-TLRDNLLL- 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1399 gAVKGMSPGDMKEVISRI--TKALDLKEHLQKTV----KKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMW 1472
Cdd:PRK11160 437 -AAPNASDEALIEVLQQVglEKLLEDDKGLNAWLgeggRQLSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAETERQIL 515
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 1473 RAIRTAFKNKkrAALLTTHYMEEAEAVcDRVAIMVSGQLRCIGTVQHLKSKFGkGYF 1529
Cdd:PRK11160 516 ELLAEHAQNK--TVLMITHRLTGLEQF-DRICVMDNGQIIEQGTHQELLAQQG-RYY 568
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
492-695 |
2.57e-09 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 59.70 E-value: 2.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 492 ENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGL--CPPSDGFASIYGHRVSE--IDEmfEARKMIGICPQSDIN 567
Cdd:COG0396 11 EGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHpkYEVTSGSILLDGEDILElsPDE--RARAGIFLAFQYPVE 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 568 FDVLTVEENL-SILASIKG--IPANNIIQEVQKVL--LDLDMQAIKDNQAKKLSGGQKRKLSV-GIAVLgNPKILLLDEP 641
Cdd:COG0396 89 IPGVSVSNFLrTALNARRGeeLSAREFLKLLKEKMkeLGLDEDFLDRYVNEGFSGGEKKRNEIlQMLLL-EPKLAILDET 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 146134400 642 TAGMDpcsrhiVWNL-------LKYRKANRVTVFSTH---FMDEadILADRKAVISQGMLKCVG 695
Cdd:COG0396 168 DSGLD------IDALrivaegvNKLRSPDRGILIITHyqrILDY--IKPDFVHVLVDGRIVKSG 223
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
1328-1522 |
2.87e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 60.11 E-value: 2.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1328 ILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGD--YGSHSSEDDESI----KCMGYCPQTNPLWPDLTLQEHFEIYGAV 1401
Cdd:PRK14271 49 VTSLMGPTGSGKTTFLRTLNRMNDKVSGYRYSGDvlLGGRSIFNYRDVlefrRRVGMLFQRPNPFPMSIMDNVLAGVRAH 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1402 KGMSPGDMKEVI-SRITKA---LDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRT 1477
Cdd:PRK14271 129 KLVPRKEFRGVAqARLTEVglwDAVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRS 208
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 146134400 1478 AfkNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKS 1522
Cdd:PRK14271 209 L--ADRLTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFS 251
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
455-691 |
2.91e-09 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 61.53 E-value: 2.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 455 INGNISLNEI----VEPVSSEFigKEAIRISGIQK------SYRKKTENVeALRNLSFDIYEGQITALLGHSGTGKSTLM 524
Cdd:PRK10522 290 LSAQVAFNKLnklaLAPYKAEF--PRPQAFPDWQTlelrnvTFAYQDNGF-SVGPINLTIKRGELLFLIGGNGSGKSTLA 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 525 NILCGLCPPSDGFASIYGHRVSEiDEMFEARKMIgicpqSDINFDVLTVEEnlsiLASIKGIPANNiiQEVQKVLLDLDM 604
Cdd:PRK10522 367 MLLTGLYQPQSGEILLDGKPVTA-EQPEDYRKLF-----SAVFTDFHLFDQ----LLGPEGKPANP--ALVEKWLERLKM 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 605 Q---AIKDNQAK--KLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWN-LLKYRKANRVTVFSTHFMDEADI 678
Cdd:PRK10522 435 AhklELEDGRISnlKLSKGQKKRLALLLALAEERDILLLDEWAADQDPHFRREFYQvLLPLLQEMGKTIFAISHDDHYFI 514
|
250
....*....|...
gi 146134400 679 LADRKAVISQGML 691
Cdd:PRK10522 515 HADRLLEMRNGQL 527
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
1288-1506 |
3.03e-09 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 58.98 E-value: 3.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1288 PAIMVCNLHKeyddkkDF-LHSRKTTK-VATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGS- 1364
Cdd:COG4778 3 TLLEVENLSK------TFtLHLQGGKRlPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDGGw 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1365 ---HSSEDDESI----KCMGYCPQ--------------TNPLwpdltlqehfeiygAVKGMSPGDMKEVISRITKALDLK 1423
Cdd:COG4778 77 vdlAQASPREILalrrRTIGYVSQflrviprvsaldvvAEPL--------------LERGVDREEARARARELLARLNLP 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1424 EHLQKTVkklPA----GIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAfknKKR-AALLT-THYMEEAE 1497
Cdd:COG4778 143 ERLWDLP---PAtfsgGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEA---KARgTAIIGiFHDEEVRE 216
|
....*....
gi 146134400 1498 AVCDRVAIM 1506
Cdd:COG4778 217 AVADRVVDV 225
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
1317-1523 |
3.06e-09 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 59.87 E-value: 3.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1317 KYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEpTSGKIFLGDYGSHSSEDDESIKCMGYCPQTNPLWPDlTLQEHFE 1396
Cdd:cd03289 21 ENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGDIQIDGVSWNSVPLQKWRKAFGVIPQKVFIFSG-TFRKNLD 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1397 IYGA------VKGMSPGDMKEVISRITKALDLKehLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQH 1470
Cdd:cd03289 99 PYGKwsdeeiWKVAEEVGLKSVIEQFPGQLDFV--LVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPITYQV 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1471 MWRAIRTAFKNKkrAALLTTHYMeEAEAVCDRVAIMVSGQLRCIGTVQHLKSK 1523
Cdd:cd03289 177 IRKTLKQAFADC--TVILSEHRI-EAMLECQRFLVIEENKVRQYDSIQKLLNE 226
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
479-646 |
3.48e-09 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 59.61 E-value: 3.48e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 479 RISGIQKS--YRKKTenveALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARK 556
Cdd:PRK10253 7 RLRGEQLTlgYGKYT----VAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 mIGICPQSDINFDVLTVEEnlsiLASIKGIPANNII--------QEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIA 628
Cdd:PRK10253 83 -IGLLAQNATTPGDITVQE----LVARGRYPHQPLFtrwrkedeEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMV 157
|
170
....*....|....*...
gi 146134400 629 VLGNPKILLLDEPTAGMD 646
Cdd:PRK10253 158 LAQETAIMLLDEPTTWLD 175
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
485-681 |
4.35e-09 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 58.43 E-value: 4.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 485 KSYRKKTENVeaLRNLSFDIYEGQITALLGHSGTGKSTLMNILcglcppsdgfasiyghrvseidemfeARKMIGICPQS 564
Cdd:COG2401 36 VELRVVERYV--LRDLNLEIEPGEIVLIVGASGSGKSTLLRLL--------------------------AGALKGTPVAG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 565 DINFDVLTVEENLSIlasIKGIPANNIIQEVQKVlldLDMQAIKDNQA-----KKLSGGQKRKLSVGIAVLGNPKILLLD 639
Cdd:COG2401 88 CVDVPDNQFGREASL---IDAIGRKGDFKDAVEL---LNAVGLSDAVLwlrrfKELSTGQKFRFRLALLLAERPKLLVID 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 146134400 640 EPTAGMDP-CSRHIVWNLLKY-RKANRVTVFSTHfmdEADILAD 681
Cdd:COG2401 162 EFCSHLDRqTAKRVARNLQKLaRRAGITLVVATH---HYDVIDD 202
|
|
| ABC2_membrane_3 |
pfam12698 |
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter ... |
860-1224 |
4.54e-09 |
|
ABC-2 family transporter protein; This family is related to the ABC-2 membrane transporter family pfam01061.
Pssm-ID: 463674 [Multi-domain] Cd Length: 345 Bit Score: 60.10 E-value: 4.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 860 KSVRAVLLLLLIFFAVQIFMFFLHHSFKNAVVPIKLVPDLYFLKPGDKPHKYKTSLLLQNSTD-SDINGLIEFFAHQNIM 938
Cdd:pfam12698 1 KSFLIITLLLPILLILLLGLIFSNAVNDPEELPVAVVDEDNSSLSRQLVRALEASPTVNLVQYvDSEEEAKEALKNGKID 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 939 VAMF--NDSDYVSAAPHSAALNVVRSEKDYVFSAVFNSTMVYCLPVMMNIISNYYLYHLNVTEAIQTWSTPFIQEITDIV 1016
Cdd:pfam12698 81 GLLVipKGFSKDLLKGESATVTVYINSSNLLVSKLILNALQSLLQQLNASALVLLLEALSTSAPIPVESTPLFNPQSGYA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1017 FkielYFQAALLGIIVTAMPPYFAMENAENHKIKAYTQLKLSGLLPSAYWVGQAVVDIPLFFVVLILMLGSLFafhhGLY 1096
Cdd:pfam12698 161 Y----YLVGLILMIIILIGAAIIAVSIVEEKESRIKERLLVSGVSPLQYWLGKILGDFLVGLLQLLIILLLLF----GIG 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1097 FYPAKFLAVVFCLIAYVPSVILFTYIASFTFKKILNTKEFwSFIYSVTALACVAITETTFFLQYAVTAVFHYtfciaIPI 1176
Cdd:pfam12698 233 IPFGNLGLLLLLFLLYGLAYIALGYLLGSLFKNSEDAQSI-IGIVILLLSGFFGGLFPLEDPPSFLQWIFSI-----IPF 306
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 146134400 1177 YPLLgclisfikgswkNMPKNENTYNPWDRLLVAVIMPYLQCILWIFL 1224
Cdd:pfam12698 307 FSPI------------DGLLRLIYGDSLWEIAPSLIILLLFAVVLLLL 342
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
500-647 |
5.03e-09 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 58.32 E-value: 5.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 500 LSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEmfeARKM--IGICPQSDINFDVLtveENL 577
Cdd:PRK13543 30 LDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGDR---SRFMayLGHLPGLKADLSTL---ENL 103
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 578 SILASIKGIPANniiQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDP 647
Cdd:PRK13543 104 HFLCGLHGRRAK---QMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDL 170
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
1313-1525 |
5.26e-09 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 61.01 E-value: 5.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1313 KVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGdveptsgkiFLGDYGS--------HSSEDDESIKCMGYCPQtNP 1384
Cdd:PRK11174 363 KTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLG---------FLPYQGSlkingielRELDPESWRKHLSWVGQ-NP 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1385 LWPDLTLQEHfeiygavkgMSPGDMKEVISRITKALDlKEHLQKTVKKLPAGIK---------------RKLCFALSMLG 1449
Cdd:PRK11174 433 QLPHGTLRDN---------VLLGNPDASDEQLQQALE-NAWVSEFLPLLPQGLDtpigdqaaglsvgqaQRLALARALLQ 502
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 1450 NPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKkrAALLTTHYMEEAEAvCDRVAIMVSGQLRCIGTVQHLKSKFG 1525
Cdd:PRK11174 503 PCQLLLLDEPTASLDAHSEQLVMQALNAASRRQ--TTLMVTHQLEDLAQ-WDQIWVMQDGQIVQQGDYAELSQAGG 575
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
478-646 |
7.02e-09 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 60.73 E-value: 7.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLC---------------------PPSDG 536
Cdd:PRK11147 4 ISIHGAWLSF----SDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVllddgriiyeqdlivarlqqdPPRNV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 537 FASIYGHrVSE-IDEMFEARKMIgicpqSDINFDVLT--VEENLSILASIKGIPAN-------NIIQEVQKvLLDLDmqa 606
Cdd:PRK11147 80 EGTVYDF-VAEgIEEQAEYLKRY-----HDISHLVETdpSEKNLNELAKLQEQLDHhnlwqleNRINEVLA-QLGLD--- 149
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 146134400 607 iKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMD 646
Cdd:PRK11147 150 -PDAALSSLSGGWLRKAALGRALVSNPDVLLLDEPTNHLD 188
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
476-647 |
8.31e-09 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 58.27 E-value: 8.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 476 EAIRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASI-----------YGHR 544
Cdd:COG4598 7 PALEVRDLHKSF----GDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVggeeirlkpdrDGEL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 545 VS----EIDEMfeaRKMIGICPQSdinFDV---LTVEENLsILASI--KGIPANNIIQEVQKVLLDLDMQAIKDNQAKKL 615
Cdd:COG4598 83 VPadrrQLQRI---RTRLGMVFQS---FNLwshMTVLENV-IEAPVhvLGRPKAEAIERAEALLAKVGLADKRDAYPAHL 155
|
170 180 190
....*....|....*....|....*....|..
gi 146134400 616 SGGQKRKLSVGIAVLGNPKILLLDEPTAGMDP 647
Cdd:COG4598 156 SGGQQQRAAIARALAMEPEVMLFDEPTSALDP 187
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
1259-1483 |
8.31e-09 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 60.18 E-value: 8.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1259 PINEDEDEDVKAERLKVK-----ELM-GCQCCEEK-P--AIMVCNLHKEYDDKKdfLHSRKTTkvatkyiSF------CV 1323
Cdd:COG1245 26 PVNRTGKEAIEIDEDDGKpviseELCiGCGICVKKcPfdAISIVNLPEELEEDP--VHRYGEN-------GFrlyglpVP 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1324 KKGEILGLLGPNGAGKSTVINTLVGDVEPTsgkifLGDYGSHSSEDD--------EsikcmgycpqtnplwpdltLQEHF 1395
Cdd:COG1245 97 KKGKVTGILGPNGIGKSTALKILSGELKPN-----LGDYDEEPSWDEvlkrfrgtE-------------------LQDYF 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1396 E------------------IYGAVKG-----MSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQ 1452
Cdd:COG1245 153 KklangeikvahkpqyvdlIPKVFKGtvrelLEKVDERGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDAD 232
|
250 260 270
....*....|....*....|....*....|.
gi 146134400 1453 VTLLDEPSTGMDPRAKQHMWRAIRTAFKNKK 1483
Cdd:COG1245 233 FYFFDEPSSYLDIYQRLNVARLIRELAEEGK 263
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
1326-1467 |
1.41e-08 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 59.51 E-value: 1.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1326 GEILGLLGPNGAGKSTVINTLVGDVEPTS--GKIFLGDygshSSEDDESIKCMGYCPQTNPLWPDLTLQEHFeIYGAVKG 1403
Cdd:PLN03211 94 GEILAVLGPSGSGKSTLLNALAGRIQGNNftGTILANN----RKPTKQILKRTGFVTQDDILYPHLTVRETL-VFCSLLR 168
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1404 MSPGDMKEVISRITKALDLKEHLQKT---------VKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRA 1467
Cdd:PLN03211 169 LPKSLTKQEKILVAESVISELGLTKCentiignsfIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATA 241
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
496-671 |
1.44e-08 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 59.65 E-value: 1.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 496 ALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIdEMFEARKMIGICPQSDINFdvltvee 575
Cdd:PRK11176 358 ALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDY-TLASLRNQVALVSQNVHLF------- 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 576 NLSIlasikgipANNI------------IQEVQKVLLDLDM---------QAIKDNQAkKLSGGQKRKLSVGIAVLGNPK 634
Cdd:PRK11176 430 NDTI--------ANNIayarteqysreqIEEAARMAYAMDFinkmdngldTVIGENGV-LLSGGQRQRIAIARALLRDSP 500
|
170 180 190
....*....|....*....|....*....|....*..
gi 146134400 635 ILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTH 671
Cdd:PRK11176 501 ILILDEATSALDTESERAIQAALDELQKNRTSLVIAH 537
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
1326-1520 |
1.58e-08 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 57.49 E-value: 1.58e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1326 GEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQEHFEI-----YGA 1400
Cdd:PRK10575 37 GKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPAAEGMTVRELVAIgrypwHGA 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1401 VKGMSPGDMKEVISRITkALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFK 1480
Cdd:PRK10575 117 LGRFGAADREKVEEAIS-LVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQ 195
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 146134400 1481 NKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL 1520
Cdd:PRK10575 196 ERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEL 235
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
478-642 |
1.68e-08 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 59.25 E-value: 1.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSeidemFEARKM 557
Cdd:PRK10762 5 LQLKGIDKAF----PGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVT-----FNGPKS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 -----IGICPQsDINF-DVLTVEENL----SILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGI 627
Cdd:PRK10762 76 sqeagIGIIHQ-ELNLiPQLTIAENIflgrEFVNRFGRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAK 154
|
170
....*....|....*
gi 146134400 628 AVLGNPKILLLDEPT 642
Cdd:PRK10762 155 VLSFESKVIIMDEPT 169
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
489-657 |
1.73e-08 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 58.05 E-value: 1.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 489 KKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEA--RKMIGIC----- 561
Cdd:PRK11308 23 KPERLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLKADPEAQKllRQKIQIVfqnpy 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 562 ----PQSDINFdvlTVEENLSILASIkgipanNIIQEVQKVLLDLDMQAIKDNQAKK----LSGGQKRKLSVGIAVLGNP 633
Cdd:PRK11308 103 gslnPRKKVGQ---ILEEPLLINTSL------SAAERREKALAMMAKVGLRPEHYDRyphmFSGGQRQRIAIARALMLDP 173
|
170 180
....*....|....*....|....
gi 146134400 634 KILLLDEPTAGMDPCSRHIVWNLL 657
Cdd:PRK11308 174 DVVVADEPVSALDVSVQAQVLNLM 197
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
1319-1511 |
1.95e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 57.41 E-value: 1.95e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgDYGSHSSEDDESIK-CMGYCPQtNP--LWPDLTLQEHF 1395
Cdd:PRK13642 26 VSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKI-DGELLTAENVWNLRrKIGMVFQ-NPdnQFVGATVEDDV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1396 EIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAI 1475
Cdd:PRK13642 104 AFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVI 183
|
170 180 190
....*....|....*....|....*....|....*..
gi 146134400 1476 RtAFKNKKRAALLT-THYMEEAeAVCDRVAIMVSGQL 1511
Cdd:PRK13642 184 H-EIKEKYQLTVLSiTHDLDEA-ASSDRILVMKAGEI 218
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
1319-1530 |
2.02e-08 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 56.73 E-value: 2.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQTNPLWpDLTLQEHfeIY 1398
Cdd:cd03252 21 ISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWLRRQVGVVLQENVLF-NRSIRDN--IA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1399 GAVKGMspgDMKEVI--SRITKA----LDLKEHLQKTVKK----LPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAK 1468
Cdd:cd03252 98 LADPGM---SMERVIeaAKLAGAhdfiSELPEGYDTIVGEqgagLSGGQRQRIAIARALIHNPRILIFDEATSALDYESE 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146134400 1469 QHMWRAIRTAFKNkkRAALLTTHYMEEAEAVcDRVAIMVSGQLRCIGTVQHLKSKFGKGYFL 1530
Cdd:cd03252 175 HAIMRNMHDICAG--RTVIIIAHRLSTVKNA-DRIIVMEKGRIVEQGSHDELLAENGLYAYL 233
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
1319-1510 |
2.25e-08 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 56.12 E-value: 2.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPT---SGKIflgDYGSHSSeDDESIKCMG---YCPQTNPLWPDLTLQ 1392
Cdd:cd03233 26 FSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDI---HYNGIPY-KEFAEKYPGeiiYVSEEDVHFPTLTVR 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1393 EHFEIygavkgmspgdmkevisritkALDLKEHlqKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMW 1472
Cdd:cd03233 102 ETLDF---------------------ALRCKGN--EFVRGISGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTALEIL 158
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 146134400 1473 RAIRTaFKNKKRAALLTTHYM--EEAEAVCDRVAIMVSGQ 1510
Cdd:cd03233 159 KCIRT-MADVLKTTTFVSLYQasDEIYDLFDKVLVLYEGR 197
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
1290-1511 |
2.66e-08 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 56.90 E-value: 2.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKKdflhsrkttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSED 1369
Cdd:PRK10619 6 LNVIDLHKRYGEHE-----------VLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 -DESIKC------------MGYCPQTNPLWPDLTLQEH-FEIYGAVKGMSPGDMKEVISRITKALDLKEHLQ-KTVKKLP 1434
Cdd:PRK10619 75 kDGQLKVadknqlrllrtrLTMVFQHFNLWSHMTVLENvMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQgKYPVHLS 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 1435 AGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRaIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:PRK10619 155 GGQQQRVSIARALAMEPEVLLFDEPTSALDPELVGEVLR-IMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKI 230
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
1290-1511 |
2.82e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 57.40 E-value: 2.82e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKKdflhsrKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI---FLGDYGSHS 1366
Cdd:PRK13651 3 IKVKNIVKIFNKKL------PTELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewiFKDEKNKKK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1367 SEDDESIKcmgycpqtnplwPDLTLQ--------------------------EHFE-------IYGAVK-GMSPGDMKEV 1412
Cdd:PRK13651 77 TKEKEKVL------------EKLVIQktrfkkikkikeirrrvgvvfqfaeyQLFEqtiekdiIFGPVSmGVSKEEAKKR 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1413 ISRITKALDLKE-HLQKTVKKLPAGIKRKLCFA--LSMlgNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKrAALLT 1489
Cdd:PRK13651 145 AAKYIELVGLDEsYLQRSPFELSGGQKRRVALAgiLAM--EPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGK-TIILV 221
|
250 260
....*....|....*....|..
gi 146134400 1490 THYMEEAEAVCDRVAIMVSGQL 1511
Cdd:PRK13651 222 THDLDNVLEWTKRTIFFKDGKI 243
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
487-694 |
3.04e-08 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 58.18 E-value: 3.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 487 YRKKTENVEALRNLSFDIYEGQITALLGHSGTGKS-TLMNILCGLCPPsdgfASIYghrvseidemfearkmigicPQSD 565
Cdd:PRK15134 15 FRQQQTVRTVVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSP----PVVY--------------------PSGD 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 566 INF---DVLTVEEnlsilASIKGIPANN---IIQE----------VQKVLLD--------------------LDMQAIKd 609
Cdd:PRK15134 71 IRFhgeSLLHASE-----QTLRGVRGNKiamIFQEpmvslnplhtLEKQLYEvlslhrgmrreaargeilncLDRVGIR- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 610 nQAKK--------LSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFMDEADIL 679
Cdd:PRK15134 145 -QAAKrltdyphqLSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRelQQELNMGLLFITHNLSIVRKL 223
|
250
....*....|....*
gi 146134400 680 ADRKAVISQGmlKCV 694
Cdd:PRK15134 224 ADRVAVMQNG--RCV 236
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
1311-1511 |
3.74e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 56.73 E-value: 3.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1311 TTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGdveptsgkIFLGDygshsSEDDESIKCMGYCPQTNPLW---- 1386
Cdd:PRK13640 18 SKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLING--------LLLPD-----DNPNSKITVDGITLTAKTVWdire 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1387 --------PD-----LTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQV 1453
Cdd:PRK13640 85 kvgivfqnPDnqfvgATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKI 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 1454 TLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEaVCDRVAIMVSGQL 1511
Cdd:PRK13640 165 IILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEAN-MADQVLVLDDGKL 221
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
1290-1464 |
4.11e-08 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 57.82 E-value: 4.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKkdflhsrkttkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGdygshssed 1369
Cdd:PRK11819 325 IEAENLSKSFGDR-----------LLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKIG--------- 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 dESIKcMGYCPQT-NPLWPDLTLQEhfEIYGAVKGMSPGDmKEVISRIT------KALDlkehLQKTVKKLPAGIKRKLC 1442
Cdd:PRK11819 385 -ETVK-LAYVDQSrDALDPNKTVWE--EISGGLDIIKVGN-REIPSRAYvgrfnfKGGD----QQKKVGVLSGGERNRLH 455
|
170 180
....*....|....*....|....*
gi 146134400 1443 FALsML---GNpqVTLLDEPSTGMD 1464
Cdd:PRK11819 456 LAK-TLkqgGN--VLLLDEPTNDLD 477
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
488-646 |
4.23e-08 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 58.58 E-value: 4.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 488 RKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGlcpPSDGFA-------SIYGHRVSEIDEMFeaRKMIGI 560
Cdd:TIGR00956 68 FRDTKTFDILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIAS---NTDGFHigvegviTYDGITPEEIKKHY--RGDVVY 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 561 CPQSDINFDVLTVEENLSILASIKGiPANNII----QEVQKVLLDLDMQA----------IKDNQAKKLSGGQKRKLSVG 626
Cdd:TIGR00956 143 NAETDVHFPHLTVGETLDFAARCKT-PQNRPDgvsrEEYAKHIADVYMATyglshtrntkVGNDFVRGVSGGERKRVSIA 221
|
170 180
....*....|....*....|
gi 146134400 627 IAVLGNPKILLLDEPTAGMD 646
Cdd:TIGR00956 222 EASLGGAKIQCWDNATRGLD 241
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
478-642 |
4.30e-08 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 57.77 E-value: 4.30e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKS-TLMNILcGLCPpsDGFASIYGHRVSEIDEMFEA-- 554
Cdd:COG4172 7 LSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSvTALSIL-RLLP--DPAAHPSGSILFDGQDLLGLse 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 555 RKMIGIC----------PQSDINfDVLTVEENLS-ILASIKGIPAnniiQEVQKVLLD-LDMQAIKDNQAK------KLS 616
Cdd:COG4172 84 RELRRIRgnriamifqePMTSLN-PLHTIGKQIAeVLRLHRGLSG----AAARARALElLERVGIPDPERRldayphQLS 158
|
170 180
....*....|....*....|....*.
gi 146134400 617 GGQKRKLSVGIAVLGNPKILLLDEPT 642
Cdd:COG4172 159 GGQRQRVMIAMALANEPDLLIADEPT 184
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
1319-1511 |
4.76e-08 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 55.87 E-value: 4.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTV---INTLvgdVEPTSGKIFLGDYGSHSSEDDESI--KCMGYCPQTNPLWPDLTLQE 1393
Cdd:PRK09493 20 IDLNIDQGEVVVIIGPSGSGKSTLlrcINKL---EEITSGDLIVDGLKVNDPKVDERLirQEAGMVFQQFYLFPHLTALE 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1394 HFeIYGA--VKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHM 1471
Cdd:PRK09493 97 NV-MFGPlrVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLFDEPTSALDPELRHEV 175
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 146134400 1472 WRAIRTaFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:PRK09493 176 LKVMQD-LAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRI 214
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
1285-1509 |
4.77e-08 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 57.75 E-value: 4.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1285 EEKPAIMVCNLHKEYddkkdflhsrkTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGS 1364
Cdd:PRK15439 7 TAPPLLCARSISKQY-----------SGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPC 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1365 HSSEDDESIKCMGY-CPQTNPLWPDLTLQEHFeIYGAVKGMSPGD-MKEVISRITKALDLkehlqktvkKLPAG------ 1436
Cdd:PRK15439 76 ARLTPAKAHQLGIYlVPQEPLLFPNLSVKENI-LFGLPKRQASMQkMKQLLAALGCQLDL---------DSSAGslevad 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 1437 -----IKRKLcfalsmLGNPQVTLLDEPSTGMDPRAKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSG 1509
Cdd:PRK15439 146 rqiveILRGL------MRDSRILILDEPTASLTPAETERLFSRIR-ELLAQGVGIVFISHKLPEIRQLADRISVMRDG 216
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
1313-1511 |
5.01e-08 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 55.82 E-value: 5.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1313 KVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQ 1392
Cdd:PRK14246 23 KAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLYFGKDIFQIDAIKLRKEVGMVFQQPNPF 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1393 EHFEIYGAV----KGMSPGDMKEVISRITKAL-------DLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPST 1461
Cdd:PRK14246 103 PHLSIYDNIayplKSHGIKEKREIKKIVEECLrkvglwkEVYDRLNSPASQLSGGQQQRLTIARALALKPKVLLMDEPTS 182
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 146134400 1462 GMDPRAKQHMWRAIrTAFKNKKrAALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:PRK14246 183 MIDIVNSQAIEKLI-TELKNEI-AIVIVSHNPQQVARVADYVAFLYNGEL 230
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
1319-1525 |
5.53e-08 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 58.03 E-value: 5.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGdyGShsseddesikcMGYCPQTNPLWPDlTLQEHFeIY 1398
Cdd:TIGR00957 657 ITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMK--GS-----------VAYVPQQAWIQND-SLRENI-LF 721
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1399 GavKGMSPGDMKEVISRITKALDLK--------EHLQKTVkKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQH 1470
Cdd:TIGR00957 722 G--KALNEKYYQQVLEACALLPDLEilpsgdrtEIGEKGV-NLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKH 798
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 1471 MWRAI---RTAFKNKKRaaLLTTHYMEEAEAVcDRVAIMVSGQLRCIGTVQHLKSKFG 1525
Cdd:TIGR00957 799 IFEHVigpEGVLKNKTR--ILVTHGISYLPQV-DVIIVMSGGKISEMGSYQELLQRDG 853
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1319-1510 |
5.58e-08 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 57.53 E-value: 5.58e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGdVEPT---SGKI-FLGDYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQEH 1394
Cdd:TIGR02633 20 IDLEVRPGECVGLCGENGAGKSTLMKILSG-VYPHgtwDGEIyWSGSPLKASNIRDTERAGIVIIHQELTLVPELSVAEN 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1395 feIYGAVKGMSPGDMKEVISRITKALDLKEHLQ-------KTVKKLPAGIKRKLCFALSMlgNPQVTL--LDEPSTGMDP 1465
Cdd:TIGR02633 99 --IFLGNEITLPGGRMAYNAMYLRAKNLLRELQldadnvtRPVGDYGGGQQQLVEIAKAL--NKQARLliLDEPSSSLTE 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 146134400 1466 RAKQHMWRAIRTaFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQ 1510
Cdd:TIGR02633 175 KETEILLDIIRD-LKAHGVACVYISHKLNEVKAVCDTICVIRDGQ 218
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
1328-1515 |
7.32e-08 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 55.78 E-value: 7.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1328 ILGLLGPNGAGKSTVINTLVGDVEPTSGKIFL-GDYGSHSSED----DESIKCMGYCPQTNPLWPDLTlqehFEIYGAVK 1402
Cdd:PRK13638 29 VTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWqGKPLDYSKRGllalRQQVATVFQDPEQQIFYTDID----SDIAFSLR 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1403 GMSPGDmKEVISRITKAL---DLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAF 1479
Cdd:PRK13638 105 NLGVPE-AEITRRVDEALtlvDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMIAIIRRIV 183
|
170 180 190
....*....|....*....|....*....|....*.
gi 146134400 1480 KNKKRaALLTTHYMEEAEAVCDRVAIMVSGQLRCIG 1515
Cdd:PRK13638 184 AQGNH-VIISSHDIDLIYEISDAVYVLRQGQILTHG 218
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
1319-1498 |
7.44e-08 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 54.42 E-value: 7.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshsseDDESIKCMGYCPQTNPLW--------PDLT 1390
Cdd:PRK13538 20 LSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLW---------QGEPIRRQRDEYHQDLLYlghqpgikTELT 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1391 LQEHFEIYGAVKGMSPGDmkevisRITKALD---LK--EHLqkTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDp 1465
Cdd:PRK13538 91 ALENLRFYQRLHGPGDDE------ALWEALAqvgLAgfEDV--PVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAID- 161
|
170 180 190
....*....|....*....|....*....|...
gi 146134400 1466 rakqhmwrairtafknKKRAALLTTHYMEEAEA 1498
Cdd:PRK13538 162 ----------------KQGVARLEALLAQHAEQ 178
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
1317-1522 |
8.42e-08 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 55.63 E-value: 8.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1317 KYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIflgdygSHSSEddesikcMGYCPQTNPLWPDlTLQEHFe 1396
Cdd:cd03291 54 KNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKI------KHSGR-------ISFSSQFSWIMPG-TIKENI- 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1397 iygaVKGMSPGDMKevISRITKALDLKEHLQKTVKK-----------LPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDP 1465
Cdd:cd03291 119 ----IFGVSYDEYR--YKSVVKACQLEEDITKFPEKdntvlgeggitLSGGQRARISLARAVYKDADLYLLDSPFGYLDV 192
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 1466 RAKQHMWRA-IRTAFKNKKRaaLLTTHYMEEAEaVCDRVAIMVSGQLRCIGTVQHLKS 1522
Cdd:cd03291 193 FTEKEIFEScVCKLMANKTR--ILVTSKMEHLK-KADKILILHEGSSYFYGTFSELQS 247
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
1319-1514 |
8.94e-08 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 56.66 E-value: 8.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKcMGYCPQTNP-----LWPDL---- 1389
Cdd:PRK10982 267 VSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANEAIN-HGFALVTEErrstgIYAYLdigf 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1390 -TLQEHFEIY-GAVKGMSPGDMKEVISRITKALDLKEHLQKT-VKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPR 1466
Cdd:PRK10982 346 nSLISNIRNYkNKVGLLDNSRMKSDTQWVIDSMRVKTPGHRTqIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVG 425
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 146134400 1467 AKQHMWRAIrTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCI 1514
Cdd:PRK10982 426 AKFEIYQLI-AELAKKDKGIIIISSEMPELLGITDRILVMSNGLVAGI 472
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
1317-1525 |
9.99e-08 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 57.04 E-value: 9.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1317 KYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG-----DYGSHSSEddESIKCMGYCPQ------TNPL 1385
Cdd:TIGR00958 498 KGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDgvplvQYDHHYLH--RQVALVGQEPVlfsgsvRENI 575
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1386 WPDLTLQEHFEIYGAVKGMSPGDMkevISRITKALD--LKEHLQktvkKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGM 1463
Cdd:TIGR00958 576 AYGLTDTPDEEIMAAAKAANAHDF---IMEFPNGYDteVGEKGS----QLSGGQKQRIAIARALVRKPRVLILDEATSAL 648
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146134400 1464 DPRAKQhmwrAIRTAFKNKKRAALLTTHYMEEAEAvCDRVAIMVSGQLRCIGTVQHLKSKFG 1525
Cdd:TIGR00958 649 DAECEQ----LLQESRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQLMEDQG 705
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
1319-1511 |
1.00e-07 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 56.55 E-value: 1.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG-------------DYG-SHSSEDDE--------SIK-C 1375
Cdd:PRK10762 271 VSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDghevvtrspqdglANGiVYISEDRKrdglvlgmSVKeN 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1376 MgycpqtnplwpDLTLQEHF-EIYGAVKGmspGDMKEVISRITKALDLKE-HLQKTVKKLPAGIKRKLCFALSMLGNPQV 1453
Cdd:PRK10762 351 M-----------SLTALRYFsRAGGSLKH---ADEQQAVSDFIRLFNIKTpSMEQAIGLLSGGNQQKVAIARGLMTRPKV 416
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 1454 TLLDEPSTGMDPRAKQHMWRAIrTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:PRK10762 417 LILDEPTRGVDVGAKKEIYQLI-NQFKAEGLSIILVSSEMPEVLGMSDRILVMHEGRI 473
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
1317-1511 |
1.23e-07 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 54.40 E-value: 1.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1317 KYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLgdygshssedDEsiKCMgycpqtnPLWPDLTLQEHFE 1396
Cdd:cd03248 31 QDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLL----------DG--KPI-------SQYEHKYLHSKVS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1397 IYGAVKGMSPGDMKEVIS---------RITKALDlKEHLQKTVKKLPAGI---------------KRKLCFALSMLGNPQ 1452
Cdd:cd03248 92 LVGQEPVLFARSLQDNIAyglqscsfeCVKEAAQ-KAHAHSFISELASGYdtevgekgsqlsggqKQRVAIARALIRNPQ 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 1453 VTLLDEPSTGMDPRAKQHMWRAIRTAfkNKKRAALLTTHYMEEAEAVcDRVAIMVSGQL 1511
Cdd:cd03248 171 VLILDEATSALDAESEQQVQQALYDW--PERRTVLVIAHRLSTVERA-DQILVLDGGRI 226
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
1317-1515 |
1.45e-07 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 54.46 E-value: 1.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1317 KYISFCVKKGEILGLLGPNGAGKSTVINTL-----VGDVEPTSGKIFLGDYGSHSSEDD--ESIKCMGYCPQTNPLWPDL 1389
Cdd:PRK14267 21 KGVDLKIPQNGVFALMGPSGCGKSTLLRTFnrlleLNEEARVEGEVRLFGRNIYSPDVDpiEVRREVGMVFQYPNPFPHL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1390 TLQEHFEIYGAVKGMSPGDmKEVISRITKAL-------DLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTG 1462
Cdd:PRK14267 101 TIYDNVAIGVKLNGLVKSK-KELDERVEWALkkaalwdEVKDRLNDYPSNLSGGQRQRLVIARALAMKPKILLMDEPTAN 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 146134400 1463 MDPRAKQHMWRAIrtaFKNKKRAAL-LTTHYMEEAEAVCDRVAIMVSGQLRCIG 1515
Cdd:PRK14267 180 IDPVGTAKIEELL---FELKKEYTIvLVTHSPAQAARVSDYVAFLYLGKLIEVG 230
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
491-677 |
1.59e-07 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 53.87 E-value: 1.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 491 TENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfaSIYGHRVSEIDEMFEA-----RKMIGICPQSD 565
Cdd:cd03290 11 GSGLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEG--KVHWSNKNESEPSFEAtrsrnRYSVAYAAQKP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 566 INFDVlTVEENLSIlasikGIPANN----IIQEVQKVLLDLDMQAIKDN-----QAKKLSGGQKRKLSVGIAVLGNPKIL 636
Cdd:cd03290 89 WLLNA-TVEENITF-----GSPFNKqrykAVTDACSLQPDIDLLPFGDQteigeRGINLSGGQRQRICVARALYQNTNIV 162
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 146134400 637 LLDEPTAGMD-PCSRHIVW-NLLKY-RKANRVTVFSTH---FMDEAD 677
Cdd:cd03290 163 FLDDPFSALDiHLSDHLMQeGILKFlQDDKRTLVLVTHklqYLPHAD 209
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
1319-1494 |
1.92e-07 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 56.46 E-value: 1.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVgDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQ-----TNPLWPDLTLQE 1393
Cdd:TIGR01271 1238 LSFSVEGGQRVGLLGRTGSGKSTLLSALL-RLLSTEGEIQIDGVSWNSVTLQTWRKAFGVIPQkvfifSGTFRKNLDPYE 1316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1394 HF---EIYGAVKGMSpgdMKEVISRITKALDLKehLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQH 1470
Cdd:TIGR01271 1317 QWsdeEIWKVAEEVG---LKSVIEQFPDKLDFV--LVDGGYVLSNGHKQLMCLARSILSKAKILLLDEPSAHLDPVTLQI 1391
|
170 180
....*....|....*....|....
gi 146134400 1471 MWRAIRTAFKNKkrAALLTTHYME 1494
Cdd:TIGR01271 1392 IRKTLKQSFSNC--TVILSEHRVE 1413
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
1328-1517 |
2.06e-07 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 54.88 E-value: 2.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1328 ILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDygsHSSEDDESIKCM-------GYCPQTNPLWPdltlqeHFEIYGA 1400
Cdd:PRK11144 26 ITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNG---RVLFDAEKGICLppekrriGYVFQDARLFP------HYKVRGN 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1401 VK-GMSPgDMKEVISRITKALDLkEHLqktVKKLPA----GIKRKLCFALSMLGNPQVTLLDEPSTGMD-PRAKQHMWRA 1474
Cdd:PRK11144 97 LRyGMAK-SMVAQFDKIVALLGI-EPL---LDRYPGslsgGEKQRVAIGRALLTAPELLLMDEPLASLDlPRKRELLPYL 171
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 146134400 1475 IRTAfKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTV 1517
Cdd:PRK11144 172 ERLA-REINIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPL 213
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
490-658 |
2.06e-07 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 54.71 E-value: 2.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 490 KTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDE--MFEARK---MIGICPQS 564
Cdd:PRK15079 30 PPKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDdeWRAVRSdiqMIFQDPLA 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 565 DINfDVLTVEEnlsilasikgipannIIQEVQKVLL-DLDMQAIKD---NQAKKL--------------SGGQKRKLSVG 626
Cdd:PRK15079 110 SLN-PRMTIGE---------------IIAEPLRTYHpKLSRQEVKDrvkAMMLKVgllpnlinryphefSGGQCQRIGIA 173
|
170 180 190
....*....|....*....|....*....|..
gi 146134400 627 IAVLGNPKILLLDEPTAGMDPCSRHIVWNLLK 658
Cdd:PRK15079 174 RALILEPKLIICDEPVSALDVSIQAQVVNLLQ 205
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
495-646 |
2.11e-07 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 55.71 E-value: 2.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 495 EALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfasiyghrvseidemfEARKMIGIC-------PQSDIN 567
Cdd:TIGR03719 19 EILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNG----------------EARPQPGIKvgylpqePQLDPT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 568 FDVL-TVEENLS----ILASIKGIPAN-------------------NIIQEVQkvLLDLD------MQAIK----DNQAK 613
Cdd:TIGR03719 83 KTVReNVEEGVAeikdALDRFNEISAKyaepdadfdklaaeqaelqEIIDAAD--AWDLDsqleiaMDALRcppwDADVT 160
|
170 180 190
....*....|....*....|....*....|...
gi 146134400 614 KLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMD 646
Cdd:TIGR03719 161 KLSGGERRRVALCRLLLSKPDMLLLDEPTNHLD 193
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
488-646 |
2.12e-07 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 55.46 E-value: 2.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 488 RKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCpPSDGFASIYGHRVSEID--EMFEARKMIGICPQ-- 563
Cdd:COG4172 293 RRTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIRFDGQDLDGLSrrALRPLRRRMQVVFQdp 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 564 ----------SDInfdvltVEENLSILAsiKGIPANNIIQEVQKVL----LDLDMQaikDNQAKKLSGGQK-RklsVGIA 628
Cdd:COG4172 372 fgslsprmtvGQI------IAEGLRVHG--PGLSAAERRARVAEALeevgLDPAAR---HRYPHEFSGGQRqR---IAIA 437
|
170 180
....*....|....*....|.
gi 146134400 629 ---VLgNPKILLLDEPTAGMD 646
Cdd:COG4172 438 ralIL-EPKLLVLDEPTSALD 457
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
1317-1523 |
2.55e-07 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 56.07 E-value: 2.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1317 KYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIflgdygSHSSEddesikcMGYCPQTNPLWPDlTLQEHFe 1396
Cdd:TIGR01271 443 KNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKI------KHSGR-------ISFSPQTSWIMPG-TIKDNI- 507
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1397 iygaVKGMSPGDMKevISRITKALDLKEHLQKTVKK-----------LPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDP 1465
Cdd:TIGR01271 508 ----IFGLSYDEYR--YTSVIKACQLEEDIALFPEKdktvlgeggitLSGGQRARISLARAVYKDADLYLLDSPFTHLDV 581
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 1466 RAKQHMW-RAIRTAFKNKKRaaLLTTHYMEEAEAVcDRVAIMVSGQLRCIGTVQHLKSK 1523
Cdd:TIGR01271 582 VTEKEIFeSCLCKLMSNKTR--ILVTSKLEHLKKA-DKILLLHEGVCYFYGTFSELQAK 637
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
1324-1491 |
3.02e-07 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 55.62 E-value: 3.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1324 KKGEILGLLGPNGAGKSTVINTLVGdvEPTSGKIfLGDY--GSHSSEDDESIKCMGYCPQTNPLWPDLTLQEHFeIYGAV 1401
Cdd:PLN03140 904 RPGVLTALMGVSGAGKTTLMDVLAG--RKTGGYI-EGDIriSGFPKKQETFARISGYCEQNDIHSPQVTVRESL-IYSAF 979
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1402 ----KGMSPGDMKEVISRITKALDLkEHLQKTVKKLPaGI-------KRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQH 1470
Cdd:PLN03140 980 lrlpKEVSKEEKMMFVDEVMELVEL-DNLKDAIVGLP-GVtglsteqRKRLTIAVELVANPSIIFMDEPTSGLDARAAAI 1057
|
170 180
....*....|....*....|.
gi 146134400 1471 MWRAIRTAFkNKKRAALLTTH 1491
Cdd:PLN03140 1058 VMRTVRNTV-DTGRTVVCTIH 1077
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
1319-1526 |
3.06e-07 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 53.54 E-value: 3.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI-FLGDygSHSSEDDESIKCMGYCPQtnplwpdLTLQEHFei 1397
Cdd:PRK10419 31 VSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVsWRGE--PLAKLNRAQRKAFRRDIQ-------MVFQDSI-- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1398 yGAVK-----------------GMSPGDMKEVISRITKALDLK-EHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEP 1459
Cdd:PRK10419 100 -SAVNprktvreiireplrhllSLDKAERLARASEMLRAVDLDdSVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEA 178
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1460 STGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQL---RCIGTVQHLKSKFGK 1526
Cdd:PRK10419 179 VSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIvetQPVGDKLTFSSPAGR 248
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
1303-1493 |
3.30e-07 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 52.95 E-value: 3.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1303 KDFLHSRKttkvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFlgdYGSH------SSEDDESIKCM 1376
Cdd:PRK10908 9 KAYLGGRQ----ALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIW---FSGHditrlkNREVPFLRRQI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1377 GYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEvisRITKALDlKEHLQKTVKKLP----AGIKRKLCFALSMLGNPQ 1452
Cdd:PRK10908 82 GMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRR---RVSAALD-KVGLLDKAKNFPiqlsGGEQQRVGIARAVVNKPA 157
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 146134400 1453 VTLLDEPSTGMDPRAKQHMWRAIRtAFKNKKRAALLTTHYM 1493
Cdd:PRK10908 158 VLLADEPTGNLDDALSEGILRLFE-EFNRVGVTVLMATHDI 197
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
1292-1464 |
3.61e-07 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 53.64 E-value: 3.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1292 VCNLHKEYDDKKDFLHsRKTTKvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFL-------GDYGS 1364
Cdd:PRK15112 7 VRNLSKTFRYRTGWFR-RQTVE-AVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIddhplhfGDYSY 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1365 HSseddESIKcMGYCPQTNPLWP--------DLTLQEHFEIygavkgMSPGDMKEVISRITKALDLKEHLQKTVKKLPAG 1436
Cdd:PRK15112 85 RS----QRIR-MIFQDPSTSLNPrqrisqilDFPLRLNTDL------EPEQREKQIIETLRQVGLLPDHASYYPHMLAPG 153
|
170 180
....*....|....*....|....*...
gi 146134400 1437 IKRKLCFALSMLGNPQVTLLDEPSTGMD 1464
Cdd:PRK15112 154 QKQRLGLARALILRPKVIIADEALASLD 181
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
1305-1520 |
3.62e-07 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 54.86 E-value: 3.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1305 FLHSRKTTKvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG------------DYGSHSSEDDES 1372
Cdd:PRK10261 22 FMQEQQKIA-AVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDkmllrrrsrqviELSEQSAAQMRH 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1373 IK----CMGYCPQTNPLWPDLTLQEhfEIYGAVKGMSPGDMKEVISRITKALDL------KEHLQKTVKKLPAGIKRKLC 1442
Cdd:PRK10261 101 VRgadmAMIFQEPMTSLNPVFTVGE--QIAESIRLHQGASREEAMVEAKRMLDQvripeaQTILSRYPHQLSGGMRQRVM 178
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 1443 FALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHL 1520
Cdd:PRK10261 179 IAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQI 256
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
491-695 |
4.56e-07 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 54.48 E-value: 4.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 491 TENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEID--EMFEARKMI---------G 559
Cdd:PRK10261 334 TREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSpgKLQALRRDIqfifqdpyaS 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 560 ICPQSDINFDVLtveENLSILASIKGIPANniiqevQKVLLDLDMQAIKDNQA----KKLSGGQKRKLSVGIAVLGNPKI 635
Cdd:PRK10261 414 LDPRQTVGDSIM---EPLRVHGLLPGKAAA------ARVAWLLERVGLLPEHAwrypHEFSGGQRQRICIARALALNPKV 484
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146134400 636 LLLDEPTAGMDPCSRHIVWNLL--KYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVG 695
Cdd:PRK10261 485 IIADEAVSALDVSIRGQIINLLldLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
477-646 |
4.75e-07 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 54.98 E-value: 4.75e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYRKKTENVeaLRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDeMFEARK 556
Cdd:PLN03232 1234 SIKFEDVHLRYRPGLPPV--LHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFG-LTDLRR 1310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPQSDINFDVlTVEENLSILAS------IKGIPANNIIQEVQKVLLDLDMQAIKDNQakKLSGGQKRKLSVGIAVL 630
Cdd:PLN03232 1311 VLSIIPQSPVLFSG-TVRFNIDPFSEhndadlWEALERAHIKDVIDRNPFGLDAEVSEGGE--NFSVGQRQLLSLARALL 1387
|
170
....*....|....*.
gi 146134400 631 GNPKILLLDEPTAGMD 646
Cdd:PLN03232 1388 RRSKILVLDEATASVD 1403
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
494-695 |
4.85e-07 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 54.08 E-value: 4.85e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 494 VEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMfEARKMIGICPQS---DINFDV 570
Cdd:PRK09536 16 TTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSAR-AASRRVASVPQDtslSFEFDV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 571 LTVEE-----NLSILASIKgiPANNiiQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGM 645
Cdd:PRK09536 95 RQVVEmgrtpHRSRFDTWT--ETDR--AAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASL 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 146134400 646 DpcSRHIVWNLLKYRK---ANRVTVFSTHFMDEADILADRKAVISQGMLKCVG 695
Cdd:PRK09536 171 D--INHQVRTLELVRRlvdDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAG 221
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1319-1512 |
5.17e-07 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 54.45 E-value: 5.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPT-SGKIFLGDYGSHSSEDDESIK---CM--------GYCPQTNpLW 1386
Cdd:TIGR02633 279 VSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKfEGNVFINGKPVDIRNPAQAIRagiAMvpedrkrhGIVPILG-VG 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1387 PDLTLQEhFEIYGAVKGMSPGDMKEVISRITKALDLKE-HLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDP 1465
Cdd:TIGR02633 358 KNITLSV-LKSFCFKMRIDAAAELQIIGSAIQRLKVKTaSPFLPIGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDV 436
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 146134400 1466 RAKQHMWRAIrTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLR 1512
Cdd:TIGR02633 437 GAKYEIYKLI-NQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGKLK 482
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
493-691 |
5.31e-07 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 54.35 E-value: 5.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 493 NVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSE------IDEMF----EARKMIGICP 562
Cdd:PRK10982 260 RQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNhnaneaINHGFalvtEERRSTGIYA 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 563 QSDINFDvltveenlSILASIK------GIPANNIIQEvqkvlldlDMQAIKDNQAKK----------LSGGQKRKLSVG 626
Cdd:PRK10982 340 YLDIGFN--------SLISNIRnyknkvGLLDNSRMKS--------DTQWVIDSMRVKtpghrtqigsLSGGNQQKVIIG 403
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 627 IAVLGNPKILLLDEPTAGMDPCSRHIVWNL-LKYRKANRVTVFSTHFMDEADILADRKAVISQGML 691
Cdd:PRK10982 404 RWLLTQPEILMLDEPTRGIDVGAKFEIYQLiAELAKKDKGIIIISSEMPELLGITDRILVMSNGLV 469
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
1308-1464 |
5.43e-07 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 52.54 E-value: 5.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1308 SRKTTKVaTKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDygshssEDDESIKC------MGYCPQ 1381
Cdd:cd03249 12 SRPDVPI-LKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDG------VDIRDLNLrwlrsqIGLVSQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1382 tNPLWPDLTLQEHFEiYGAvkgmSPGDMKEVISRITKA------LDLKEHLQKTV----KKLPAGIKRKLCFALSMLGNP 1451
Cdd:cd03249 85 -EPVLFDGTIAENIR-YGK----PDATDEEVEEAAKKAnihdfiMSLPDGYDTLVgergSQLSGGQKQRIAIARALLRNP 158
|
170
....*....|...
gi 146134400 1452 QVTLLDEPSTGMD 1464
Cdd:cd03249 159 KILLLDEATSALD 171
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
1313-1464 |
5.53e-07 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 53.07 E-value: 5.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1313 KVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQ 1392
Cdd:PRK10253 20 YTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATTPGDITVQ 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1393 EHfeiygAVKGMSP---------GDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGM 1463
Cdd:PRK10253 100 EL-----VARGRYPhqplftrwrKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWL 174
|
.
gi 146134400 1464 D 1464
Cdd:PRK10253 175 D 175
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
465-646 |
6.02e-07 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 54.41 E-value: 6.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 465 VEPVSSEFIGKEAIRISGIQKSYRKKTENVEAlrnlsFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfasiyghr 544
Cdd:COG1245 329 VHAPRREKEEETLVEYPDLTKSYGGFSLEVEG-----GEIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEG-------- 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 545 vsEIDEmfEARkmIGICPQ---SDINfdvLTVEENLSilASIKGIPANNIIQEvqKVLLDLDMQAIKDNQAKKLSGGQKR 621
Cdd:COG1245 396 --EVDE--DLK--ISYKPQyisPDYD---GTVEEFLR--SANTDDFGSSYYKT--EIIKPLGLEKLLDKNVKDLSGGELQ 462
|
170 180
....*....|....*....|....*
gi 146134400 622 KLSVGIAVLGNPKILLLDEPTAGMD 646
Cdd:COG1245 463 RVAIAACLSRDADLYLLDEPSAHLD 487
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
497-671 |
6.21e-07 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 51.87 E-value: 6.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEiDEMFEARKMIGICPQSDINfDVLTVEEN 576
Cdd:PRK13540 17 LQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKK-DLCTYQKQLCFVGHRSGIN-PYLTLREN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 577 lsILASIKGIPANNIIQEVQKVlldLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCS-RHIVWN 655
Cdd:PRK13540 95 --CLYDIHFSPGAVGITELCRL---FSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSlLTIITK 169
|
170
....*....|....*.
gi 146134400 656 LLKYRKANRVTVFSTH 671
Cdd:PRK13540 170 IQEHRAKGGAVLLTSH 185
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
1319-1464 |
6.98e-07 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 52.54 E-value: 6.98e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGdVEPTSGKIFLgdygshsseDDESIKCM---------GYCPQTNPLWPDL 1389
Cdd:COG4138 15 ISAQVNAGELIHLIGPNGAGKSTLLARMAG-LLPGQGEILL---------NGRPLSDWsaaelarhrAYLSQQQSPPFAM 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1390 TLQEHFEIYGAVKGMSPGDmKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSML-----GNP--QVTLLDEPSTG 1462
Cdd:COG4138 85 PVFQYLALHQPAGASSEAV-EQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLqvwptINPegQLLLLDEPMNS 163
|
..
gi 146134400 1463 MD 1464
Cdd:COG4138 164 LD 165
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
465-646 |
8.25e-07 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 53.66 E-value: 8.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 465 VEPVSSEFIGKEAIRISGIQKSYRKKTENVEAlrnlsFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASiyghr 544
Cdd:PRK13409 328 ERPPRDESERETLVEYPDLTKKLGDFSLEVEG-----GEIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVD----- 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 545 vSEIDemfearkmIGICPQS-DINFDVlTVEENLSilaSIKGIPANNIIQEvqKVLLDLDMQAIKDNQAKKLSGGQKRKL 623
Cdd:PRK13409 398 -PELK--------ISYKPQYiKPDYDG-TVEDLLR---SITDDLGSSYYKS--EIIKPLQLERLLDKNVKDLSGGELQRV 462
|
170 180
....*....|....*....|...
gi 146134400 624 SVGIAVLGNPKILLLDEPTAGMD 646
Cdd:PRK13409 463 AIAACLSRDADLYLLDEPSAHLD 485
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
497-667 |
9.46e-07 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 50.62 E-value: 9.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFasiyghrvseidemfearkmIGICPQSDINFdvltveen 576
Cdd:cd03223 17 LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGR--------------------IGMPEGEDLLF-------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 577 lsilasikgIPanniiqevQKVLLDLD--MQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVW 654
Cdd:cd03223 69 ---------LP--------QRPYLPLGtlREQLIYPWDDVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLY 131
|
170
....*....|...
gi 146134400 655 NLLKYRKANRVTV 667
Cdd:cd03223 132 QLLKELGITVISV 144
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
1303-1529 |
9.50e-07 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 53.96 E-value: 9.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1303 KDFLHSRKTTKVAT-KYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVE----PTSGKIflgDYGSHSSED------DE 1371
Cdd:TIGR00956 63 RKLKKFRDTKTFDIlKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASNTDgfhiGVEGVI---TYDGITPEEikkhyrGD 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1372 SIkcmgYCPQTNPLWPDLTLQEHFEIYGAVKGmsPGDMKEVISRITKALDLKE---------HLQKT------VKKLPAG 1436
Cdd:TIGR00956 140 VV----YNAETDVHFPHLTVGETLDFAARCKT--PQNRPDGVSREEYAKHIADvymatyglsHTRNTkvgndfVRGVSGG 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1437 IKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHY-MEEAEAVCDRVAIMVSGQLRCIG 1515
Cdd:TIGR00956 214 ERKRVSIAEASLGGAKIQCWDNATRGLDSATALEFIRALKTSANILDTTPLVAIYQcSQDAYELFDKVIVLYEGYQIYFG 293
|
250
....*....|....*
gi 146134400 1516 TVQHLKSKFGK-GYF 1529
Cdd:TIGR00956 294 PADKAKQYFEKmGFK 308
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
1319-1464 |
1.16e-06 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 51.86 E-value: 1.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGdVEPTSGKIFLGDYGSHSSEDDESIKCMGY-CPQTNPL-----WPDLTLQ 1392
Cdd:PRK03695 15 LSAEVRAGEILHLVGPNGAGKSTLLARMAG-LLPGSGSIQFAGQPLEAWSAAELARHRAYlSQQQTPPfampvFQYLTLH 93
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 1393 EHfeiygavKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSML-----GNP--QVTLLDEPSTGMD 1464
Cdd:PRK03695 94 QP-------DKTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLqvwpdINPagQLLLLDEPMNSLD 165
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
488-692 |
1.22e-06 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 53.01 E-value: 1.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 488 RKKTENVealrnlSFDIYEGQITALLGHSGTGKSTLMNILCGLCP-PSDGFASIYGHRVS----------EIDEMFEARK 556
Cdd:PRK13549 275 IKRVDDV------SFSLRRGEILGIAGLVGAGRTELVQCLFGAYPgRWEGEIFIDGKPVKirnpqqaiaqGIAMVPEDRK 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 MIGICPqsdinfdVLTVEENLSiLASIKGIPANNIIQEVQKvlLDLDMQAIKDNQAK---------KLSGGQKRKLSVGI 627
Cdd:PRK13549 349 RDGIVP-------VMGVGKNIT-LAALDRFTGGSRIDDAAE--LKTILESIQRLKVKtaspelaiaRLSGGNQQKAVLAK 418
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 628 AVLGNPKILLLDEPTAGMDPCSRHIVWNLLkYRKANR---VTVFSTHfMDEADILADRKAVISQGMLK 692
Cdd:PRK13549 419 CLLLNPKILILDEPTRGIDVGAKYEIYKLI-NQLVQQgvaIIVISSE-LPEVLGLSDRVLVMHEGKLK 484
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
1319-1465 |
1.23e-06 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 52.07 E-value: 1.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI-FLGDYGSHSSEDD--ESIKCMGYCPQTNPLWPDLT----- 1390
Cdd:PRK11831 26 ISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEIlFDGENIPAMSRSRlyTVRKRMSMLFQSGALFTDMNvfdnv 105
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 1391 ---LQEHFEIYGAVkgmspgdMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDP 1465
Cdd:PRK11831 106 aypLREHTQLPAPL-------LHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDP 176
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
1308-1508 |
1.28e-06 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 51.11 E-value: 1.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1308 SRKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVE--PTSGKIFLGDygshsseddesikcmgycpqtNPL 1385
Cdd:COG2401 38 LRVVERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKgtPVAGCVDVPD---------------------NQF 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1386 WPDLTLQEHFEIYGavkgmSPGDMKEVISRI---TKALdlkehLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTG 1462
Cdd:COG2401 97 GREASLIDAIGRKG-----DFKDAVELLNAVglsDAVL-----WLRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSH 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 146134400 1463 MDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVS 1508
Cdd:COG2401 167 LDRQTAKRVARNLQKLARRAGITLVVATHHYDVIDDLQPDLLIFVG 212
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
1294-1360 |
1.30e-06 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 53.03 E-value: 1.30e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1294 NLHKEYDDK---KDFlhsrkttkvatkyiSFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLG 1360
Cdd:PRK11147 324 NVNYQIDGKqlvKDF--------------SAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHCG 379
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
497-696 |
1.33e-06 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 53.41 E-value: 1.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHrvseidemfearkmIGICPQSD-INFDvlTVEE 575
Cdd:TIGR00957 654 LNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS--------------VAYVPQQAwIQND--SLRE 717
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 576 NLSILASIKGiPANNIIQEVQKVLLDLDMQAIKDN-----QAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDP-CS 649
Cdd:TIGR00957 718 NILFGKALNE-KYYQQVLEACALLPDLEILPSGDRteigeKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAhVG 796
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 146134400 650 RHIVWNLL--KYRKANRVTVFSTH---FMDEADILadrkAVISQGMLKCVGS 696
Cdd:TIGR00957 797 KHIFEHVIgpEGVLKNKTRILVTHgisYLPQVDVI----IVMSGGKISEMGS 844
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
493-653 |
1.37e-06 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 53.49 E-value: 1.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 493 NVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIY-----GHRVSEIDEMFEARKMIG-------- 559
Cdd:PTZ00265 1180 NVPIYKDLTFSCDSKKTTAIVGETGSGKSTVMSLLMRFYDLKNDHHIVFknehtNDMTNEQDYQGDEEQNVGmknvnefs 1259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 560 --------------------------ICpqsDIN-------FDVLTVEE---NLSILASIKGIPANNIIQEVQKV----L 599
Cdd:PTZ00265 1260 ltkeggsgedstvfknsgkilldgvdIC---DYNlkdlrnlFSIVSQEPmlfNMSIYENIKFGKEDATREDVKRAckfaA 1336
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 600 LDLDMQAIKDNQ-------AKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIV 653
Cdd:PTZ00265 1337 IDEFIESLPNKYdtnvgpyGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLI 1397
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
1329-1464 |
1.84e-06 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 52.94 E-value: 1.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1329 LGLLGPNGAGKSTVINTLVGDVEPTSGKIF------LGDYGSHSSED-DESIKCMGYCPQTNPLWPDLTLQEHFEIYGav 1401
Cdd:PLN03073 538 IAMVGPNGIGKSTILKLISGELQPSSGTVFrsakvrMAVFSQHHVDGlDLSSNPLLYMMRCFPGVPEQKLRAHLGSFG-- 615
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1402 kgmspgdmkevisrITKALDLKehlqkTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMD 1464
Cdd:PLN03073 616 --------------VTGNLALQ-----PMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLD 659
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
1323-1510 |
2.49e-06 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 52.04 E-value: 2.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1323 VKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI-FLG---DYGShSSEDDESIKCMGY--------CPQTNPLWpdlt 1390
Cdd:PRK10982 21 VRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSIlFQGkeiDFKS-SKEALENGISMVHqelnlvlqRSVMDNMW---- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1391 LQEHfeiygAVKGM--SPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAK 1468
Cdd:PRK10982 96 LGRY-----PTKGMfvDQDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEKEV 170
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 146134400 1469 QHMWRAIRTaFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQ 1510
Cdd:PRK10982 171 NHLFTIIRK-LKERGCGIVYISHKMEEIFQLCDEITILRDGQ 211
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
494-647 |
2.51e-06 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 51.44 E-value: 2.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 494 VEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPS-----DGFasiyghRVSEIDEM----FEARKMIG--IC- 561
Cdd:COG4170 20 VKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNwhvtaDRF------RWNGIDLLklspRERRKIIGreIAm 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 562 ----PQSDINfDVLTVEENLsilasIKGIPANN---------------IIQEVQKVlldldmqAIKDNQA------KKLS 616
Cdd:COG4170 94 ifqePSSCLD-PSAKIGDQL-----IEAIPSWTfkgkwwqrfkwrkkrAIELLHRV-------GIKDHKDimnsypHELT 160
|
170 180 190
....*....|....*....|....*....|.
gi 146134400 617 GGQKRKLSVGIAVLGNPKILLLDEPTAGMDP 647
Cdd:COG4170 161 EGECQKVMIAMAIANQPRLLIADEPTNAMES 191
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
1290-1518 |
2.51e-06 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 50.85 E-value: 2.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1290 IMVCNLHKEYDDKkdflhsrkttkVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSED 1369
Cdd:COG4604 2 IEIKNVSKRYGGK-----------VVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPS 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1370 DESIKCMGYCPQTNPLWPDLTLQE--HFEIYGAVKG-MSPGDmKEVISRITKALDLKEHLQKTVKKLPAGiKRKLCF-AL 1445
Cdd:COG4604 71 RELAKRLAILRQENHINSRLTVRElvAFGRFPYSKGrLTAED-REIIDEAIAYLDLEDLADRYLDELSGG-QRQRAFiAM 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146134400 1446 SMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQ 1518
Cdd:COG4604 149 VLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPE 221
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
1319-1523 |
2.89e-06 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 52.43 E-value: 2.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQTNPLWP----------- 1387
Cdd:PLN03130 1258 LSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFGLMDLRKVLGIIPQAPVLFSgtvrfnldpfn 1337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1388 ---DLTLQEHFEiygavkgmsPGDMKEVISRITKALDLKehLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMD 1464
Cdd:PLN03130 1338 ehnDADLWESLE---------RAHLKDVIRRNSLGLDAE--VSEAGENFSVGQRQLLSLARALLRRSKILVLDEATAAVD 1406
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 1465 PRAKQHMWRAIRTAFKNKkrAALLTTHYMEEAeAVCDRVAIMVSGQLRCIGTVQHLKSK 1523
Cdd:PLN03130 1407 VRTDALIQKTIREEFKSC--TMLIIAHRLNTI-IDCDRILVLDAGRVVEFDTPENLLSN 1462
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
1323-1510 |
3.16e-06 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 51.93 E-value: 3.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1323 VKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI-FLGDYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQEHF----EI 1397
Cdd:PRK10762 27 VYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSIlYLGKEVTFNGPKSSQEAGIGIIHQELNLIPQLTIAENIflgrEF 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1398 YGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAG------IKRKLCFalsmlgNPQVTLLDEPSTGMDPRAKQHM 1471
Cdd:PRK10762 107 VNRFGRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGeqqmveIAKVLSF------ESKVIIMDEPTDALTDTETESL 180
|
170 180 190
....*....|....*....|....*....|....*....
gi 146134400 1472 WRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQ 1510
Cdd:PRK10762 181 FRVIR-ELKSQGRGIVYISHRLKEIFEICDDVTVFRDGQ 218
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
497-653 |
3.54e-06 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 51.55 E-value: 3.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPpsDGFAS---IYGHRVSEIDEMFEARKMIGICPQS-----DINF 568
Cdd:PRK10938 276 LHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHP--QGYSNdltLFGRRRGSGETIWDIKKHIGYVSSSlhldyRVST 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 569 DVLTVeenlsILA----SIkgipanNIIQEV---QKVLLD--LDMQAIKDNQAKK----LSGGQKRKLSVGIAVLGNPKI 635
Cdd:PRK10938 354 SVRNV-----ILSgffdSI------GIYQAVsdrQQKLAQqwLDILGIDKRTADApfhsLSWGQQRLALIVRALVKHPTL 422
|
170
....*....|....*...
gi 146134400 636 LLLDEPTAGMDPCSRHIV 653
Cdd:PRK10938 423 LILDEPLQGLDPLNRQLV 440
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
1319-1519 |
3.67e-06 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 51.45 E-value: 3.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKC-MGYCPQ---TNPLWPDLTLQEH 1394
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDAIRAgIMLCPEdrkAEGIIPVHSVADN 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1395 FEIyGAVKGMSPGDMkeVISRITKALDLKEHLQKTVKKLPAGikRKLCFALSMlGNPQ-------------VTLLDEPST 1461
Cdd:PRK11288 352 INI-SARRHHLRAGC--LINNRWEAENADRFIRSLNIKTPSR--EQLIMNLSG-GNQQkailgrwlsedmkVILLDEPTR 425
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 1462 GMDPRAKQHMWRAIRtAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRciGTVQH 1519
Cdd:PRK11288 426 GIDVGAKHEIYNVIY-ELAAQGVAVLFVSSDLPEVLGVADRIVVMREGRIA--GELAR 480
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
497-658 |
5.54e-06 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 50.96 E-value: 5.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfaSIygHRVSEIDEMFEARK--MIG------IC-PQSDIN 567
Cdd:COG4178 379 LEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSG--RI--ARPAGARVLFLPQRpyLPLgtlreaLLyPATAEA 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 568 FDVLTVEENLsilasikgipanniiqevQKVLLD-----LDMQAikdNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPT 642
Cdd:COG4178 455 FSDAELREAL------------------EAVGLGhlaerLDEEA---DWDQVLSLGEQQRLAFARLLLHKPDWLFLDEAT 513
|
170
....*....|....*.
gi 146134400 643 AGMDPCSRHIVWNLLK 658
Cdd:COG4178 514 SALDEENEAALYQLLR 529
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
441-646 |
5.70e-06 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 51.09 E-value: 5.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 441 SKNK---RNYKELSEGNINGNISLNEIVEPVSsEFIGKEAIRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSG 517
Cdd:TIGR03719 284 AKSKarlARYEELLSQEFQKRNETAEIYIPPG-PRLGDKVIEAENLTKAFGDKL----LIDDLSFKLPPGGIVGVIGPNG 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 518 TGKSTLMNILCGLCPPSDGFASIyGHRVSeidemfearkmIGICPQSDINFDvltveenlsilasikgiPANNIIQEVQK 597
Cdd:TIGR03719 359 AGKSTLFRMITGQEQPDSGTIEI-GETVK-----------LAYVDQSRDALD-----------------PNKTVWEEISG 409
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 598 VLLDLDMQAIKDN--------------QAKK---LSGGQKRKLSVGIAVLGNPKILLLDEPTAGMD 646
Cdd:TIGR03719 410 GLDIIKLGKREIPsrayvgrfnfkgsdQQKKvgqLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLD 475
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1319-1512 |
6.11e-06 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 50.70 E-value: 6.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGdVEP--TSGKIFLGDYGSHSSEDDESIK---CMgycpqtnplwpdltLQE 1393
Cdd:PRK13549 281 VSFSLRRGEILGIAGLVGAGRTELVQCLFG-AYPgrWEGEIFIDGKPVKIRNPQQAIAqgiAM--------------VPE 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1394 HFEIYGAVKGMSPG------------------DMKEV--ISRITKALDLK-EHLQKTVKKLPAGIKRKLCFALSMLGNPQ 1452
Cdd:PRK13549 346 DRKRDGIVPVMGVGknitlaaldrftggsridDAAELktILESIQRLKVKtASPELAIARLSGGNQQKAVLAKCLLLNPK 425
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1453 VTLLDEPSTGMDPRAKQHMWRAIrTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLR 1512
Cdd:PRK13549 426 ILILDEPTRGIDVGAKYEIYKLI-NQLVQQGVAIIVISSELPEVLGLSDRVLVMHEGKLK 484
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
496-689 |
6.26e-06 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 50.87 E-value: 6.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 496 ALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIdEMFEARKMIGICPQSDINF-DvlTVE 574
Cdd:PRK10789 330 ALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKL-QLDSWRSRLAVVSQTPFLFsD--TVA 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 575 ENLSIlasikGIPA--NNIIQEVQKV------LLDLDmQAIKDNQAKK---LSGGQKRKLSVGIAVLGNPKILLLDEPTA 643
Cdd:PRK10789 407 NNIAL-----GRPDatQQEIEHVARLasvhddILRLP-QGYDTEVGERgvmLSGGQKQRISIARALLLNAEILILDDALS 480
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 146134400 644 GMDPCSRH-IVWNLLKYRKaNRVTVFSTHFMdEADILADRKAVISQG 689
Cdd:PRK10789 481 AVDGRTEHqILHNLRQWGE-GRTVIISAHRL-SALTEASEILVMQHG 525
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
1319-1494 |
7.17e-06 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 48.87 E-value: 7.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIF----LGDYGSHSSEDDESIKCMGYCPQtNPLWPDLTLQEH 1394
Cdd:cd03290 20 INIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHwsnkNESEPSFEATRSRNRYSVAYAAQ-KPWLLNATVEEN 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1395 FeIYGavkgmSPGDmKEVISRITKA------LDLKEHLQKTVK-----KLPAGIKRKLCFALSMLGNPQVTLLDEPSTGM 1463
Cdd:cd03290 99 I-TFG-----SPFN-KQRYKAVTDAcslqpdIDLLPFGDQTEIgergiNLSGGQRQRICVARALYQNTNIVFLDDPFSAL 171
|
170 180 190
....*....|....*....|....*....|..
gi 146134400 1464 DPRAKQH-MWRAIRTAFKNKKRAALLTTHYME 1494
Cdd:cd03290 172 DIHLSDHlMQEGILKFLQDDKRTLVLVTHKLQ 203
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
506-646 |
8.29e-06 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 49.29 E-value: 8.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 506 EGQITALLGHSGTGKSTLMNILCG-----LC----PPS-DGFASIYghRVSEIDEMFEarKMIG------ICPQsdiNFD 569
Cdd:cd03236 25 EGQVLGLVGPNGIGKSTALKILAGklkpnLGkfddPPDwDEILDEF--RGSELQNYFT--KLLEgdvkviVKPQ---YVD 97
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 570 VLTVEENLSILASIKGIPANNIIQEVQKVlldLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMD 646
Cdd:cd03236 98 LIPKAVKGKVGELLKKKDERGKLDELVDQ---LELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLD 171
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
497-697 |
8.78e-06 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 50.93 E-value: 8.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfasiyghRVSeidemfeARKMIGICPQ----------SDI 566
Cdd:PTZ00243 676 LRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEG-------RVW-------AERSIAYVPQqawimnatvrGNI 741
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 567 -NFDvltvEENLSILASikgipANNIIQ-EVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAG 644
Cdd:PTZ00243 742 lFFD----EEDAARLAD-----AVRVSQlEADLAQLGGGLETEIGEKGVNLSGGQKARVSLARAVYANRDVYLLDDPLSA 812
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 645 MDP-CSRHIVWNLLKYRKANRVTVFSTHfmdEADIL--ADRKAVISQGMLKCVGSS 697
Cdd:PTZ00243 813 LDAhVGERVVEECFLGALAGKTRVLATH---QVHVVprADYVVALGDGRVEFSGSS 865
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
493-646 |
9.20e-06 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 49.72 E-value: 9.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 493 NVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPS---DGFASIYGHRV-----SEIDEM-FEARKMIGICPQ 563
Cdd:PRK09473 28 DVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANgriGGSATFNGREIlnlpeKELNKLrAEQISMIFQDPM 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 564 SDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLldldmQAIKDNQAKK--------LSGGQKRKLSVGIAVLGNPKI 635
Cdd:PRK09473 108 TSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRML-----DAVKMPEARKrmkmypheFSGGMRQRVMIAMALLCRPKL 182
|
170
....*....|.
gi 146134400 636 LLLDEPTAGMD 646
Cdd:PRK09473 183 LIADEPTTALD 193
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
482-532 |
1.20e-05 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 49.79 E-value: 1.20e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 146134400 482 GIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCP 532
Cdd:NF040905 6 GITKTF----PGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYP 52
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
1319-1533 |
1.22e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 48.97 E-value: 1.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCM----GYCPQ--TNPLWPDLTLQ 1392
Cdd:PRK13649 26 VNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKDIKQIrkkvGLVFQfpESQLFEETVLK 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1393 ------EHFeiygavkGMSPGDmKEVISRITKAL-DLKEHL-QKTVKKLPAGIKRKLCFA--LSMlgNPQVTLLDEPSTG 1462
Cdd:PRK13649 106 dvafgpQNF-------GVSQEE-AEALAREKLALvGISESLfEKNPFELSGGQMRRVAIAgiLAM--EPKILVLDEPTAG 175
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 146134400 1463 MDPRAKqhmwRAIRTAFKNKKRAAL---LTTHYMEEAEAVCDRVAIMVSGQLRCIGTVqhlKSKFGKGYFLEIK 1533
Cdd:PRK13649 176 LDPKGR----KELMTLFKKLHQSGMtivLVTHLMDDVANYADFVYVLEKGKLVLSGKP---KDIFQDVDFLEEK 242
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
1326-1511 |
1.54e-05 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 48.52 E-value: 1.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1326 GEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDesIKCMGycpQTNPLWPDLTLQEHFEIygavkGMS 1405
Cdd:PRK11247 38 GQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAEARED--TRLMF---QDARLLPWKKVIDNVGL-----GLK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1406 pGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRA 1485
Cdd:PRK11247 108 -GQWRDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRIEMQDLIESLWQQHGFT 186
|
170 180
....*....|....*....|....*.
gi 146134400 1486 ALLTTHYMEEAEAVCDRVAIMVSGQL 1511
Cdd:PRK11247 187 VLLVTHDVSEAVAMADRVLLIEEGKI 212
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
497-646 |
1.63e-05 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 49.91 E-value: 1.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHrvseidemfearkmIGICPQSDINFDVlTVEEN 576
Cdd:TIGR01271 442 LKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGR--------------ISFSPQTSWIMPG-TIKDN 506
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 577 LSILASIKGIPANNIIQEVQkVLLDLDMQAIKDNQ-----AKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMD 646
Cdd:TIGR01271 507 IIFGLSYDEYRYTSVIKACQ-LEEDIALFPEKDKTvlgegGITLSGGQRARISLARAVYKDADLYLLDSPFTHLD 580
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
501-689 |
2.21e-05 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 48.86 E-value: 2.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 501 SFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDG-----FASIygHRVSeidemFEA-RKMIgicpqSDI----NFDV 570
Cdd:PRK10938 23 SLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGerqsqFSHI--TRLS-----FEQlQKLV-----SDEwqrnNTDM 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 571 LTVEENLSilasikGIPANNIIQE-------VQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTA 643
Cdd:PRK10938 91 LSPGEDDT------GRTTAEIIQDevkdparCEQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFD 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 146134400 644 GMDPCSRHIVWNLLKYRKANRVTV------FST--HFMDEADILADRkAVISQG 689
Cdd:PRK10938 165 GLDVASRQQLAELLASLHQSGITLvlvlnrFDEipDFVQFAGVLADC-TLAETG 217
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
497-651 |
2.31e-05 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 47.90 E-value: 2.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCG-LCPPSD-------GFASIYGHRVSEIDEMFEARkMIGICPQSDINF 568
Cdd:PRK13547 17 LRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGdLTGGGAprgarvtGDVTLNGEPLAAIDAPRLAR-LRAVLPQAAQPA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 569 DVLTVEENLSI----LASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAV---------LGNPKI 635
Cdd:PRK13547 96 FAFSAREIVLLgrypHARRAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLaqlwpphdaAQPPRY 175
|
170
....*....|....*.
gi 146134400 636 LLLDEPTAGMDPCSRH 651
Cdd:PRK13547 176 LLLDEPTAALDLAHQH 191
|
|
| RsgA |
COG1162 |
Ribosome biogenesis GTPase RsgA [Translation, ribosomal structure and biogenesis]; |
492-529 |
3.40e-05 |
|
Ribosome biogenesis GTPase RsgA [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440776 [Multi-domain] Cd Length: 300 Bit Score: 47.80 E-value: 3.40e-05
10 20 30
....*....|....*....|....*....|....*...
gi 146134400 492 ENVEALRnlsfDIYEGQITALLGHSGTGKSTLMNILCG 529
Cdd:COG1162 155 EGLDELR----ELLKGKTSVLVGQSGVGKSTLINALLP 188
|
|
| YjeQ_EngC |
cd01854 |
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; ... |
492-529 |
4.07e-05 |
|
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; YjeQ (YloQ in Bacillus subtilis) is a ribosomal small subunit-dependent GTPase; hence also known as RsgA. YjeQ is a late-stage ribosomal biogenesis factor involved in the 30S subunit maturation, and it represents a protein family whose members are broadly conserved in bacteria and have been shown to be essential to the growth of E. coli and B. subtilis. Proteins of the YjeQ family contain all sequence motifs typical of the vast class of P-loop-containing GTPases, but show a circular permutation, with a G4-G1-G3 pattern of motifs as opposed to the regular G1-G3-G4 pattern seen in most GTPases. All YjeQ family proteins display a unique domain architecture, which includes an N-terminal OB-fold RNA-binding domain, the central permuted GTPase domain, and a zinc knuckle-like C-terminal cysteine domain.
Pssm-ID: 206747 [Multi-domain] Cd Length: 211 Bit Score: 46.62 E-value: 4.07e-05
10 20 30
....*....|....*....|....*....|....*...
gi 146134400 492 ENVEALRNLsfdiYEGQITALLGHSGTGKSTLMNILCG 529
Cdd:cd01854 74 EGLDELREL----LKGKTSVLVGQSGVGKSTLLNALLP 107
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1319-1516 |
5.08e-05 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 48.00 E-value: 5.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGdVEPtsgkiflgdYGSHSSE---DDESIKCMGYCP----------QTNPL 1385
Cdd:PRK13549 24 VSLKVRAGEIVSLCGENGAGKSTLMKVLSG-VYP---------HGTYEGEiifEGEELQASNIRDteragiaiihQELAL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1386 WPDLTLQEHF----EIygavkgmSPG---DMKEVISRITKAL-----DLKEHLQktVKKLPAG------IKRKLcfalsm 1447
Cdd:PRK13549 94 VKELSVLENIflgnEI-------TPGgimDYDAMYLRAQKLLaqlklDINPATP--VGNLGLGqqqlveIAKAL------ 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 1448 lgNPQVTL--LDEPSTGMDPRAKQHMWRAIRTaFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGqlRCIGT 1516
Cdd:PRK13549 159 --NKQARLliLDEPTASLTESETAVLLDIIRD-LKAHGIACIYISHKLNEVKAISDTICVIRDG--RHIGT 224
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
497-646 |
5.90e-05 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 46.77 E-value: 5.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGhRVSeidemfearkmigICPQSDINFDVlTVEEN 576
Cdd:cd03291 53 LKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSG-RIS-------------FSSQFSWIMPG-TIKEN 117
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 146134400 577 LSILASIKGIPANNIIQEVQkvlLDLDMQAI--KDNQ-----AKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMD 646
Cdd:cd03291 118 IIFGVSYDEYRYKSVVKACQ---LEEDITKFpeKDNTvlgegGITLSGGQRARISLARAVYKDADLYLLDSPFGYLD 191
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
1326-1475 |
5.92e-05 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 47.86 E-value: 5.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1326 GEILGLLGPNGAGKSTVINTLVGDVEPTSGK------IFLGDYGSHSSE---DDESikCMGYCPQTNPLWPDLTLQEHFE 1396
Cdd:PRK10636 338 GSRIGLLGRNGAGKSTLIKLLAGELAPVSGEiglakgIKLGYFAQHQLEflrADES--PLQHLARLAPQELEQKLRDYLG 415
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 146134400 1397 IYGAvkgmsPGDMkevISRITkaldlkehlqktvKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAI 1475
Cdd:PRK10636 416 GFGF-----QGDK---VTEET-------------RRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEAL 473
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
1319-1357 |
7.57e-05 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 47.26 E-value: 7.57e-05
10 20 30
....*....|....*....|....*....|....*....
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI 1357
Cdd:PRK13657 354 VSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRI 392
|
|
| RsgA_GTPase |
pfam03193 |
RsgA GTPase; RsgA (also known as EngC and YjeQ) represents a protein family whose members are ... |
492-529 |
1.10e-04 |
|
RsgA GTPase; RsgA (also known as EngC and YjeQ) represents a protein family whose members are broadly conserved in bacteria and are indispensable for growth. The GTPase domain of RsgA is very similar to several P-loop GTPases, but differs in having a circular permutation of the GTPase structure described by a G4-G1-G3 pattern.
Pssm-ID: 427191 [Multi-domain] Cd Length: 174 Bit Score: 44.45 E-value: 1.10e-04
10 20 30
....*....|....*....|....*....|....*...
gi 146134400 492 ENVEALRNLsfdiYEGQITALLGHSGTGKSTLMNILCG 529
Cdd:pfam03193 95 EGIEALKEL----LKGKTTVLAGQSGVGKSTLLNALLP 128
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
1323-1492 |
1.12e-04 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 45.55 E-value: 1.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1323 VKKGEILGLLGPNGAGKSTVINTLVG--DVEPTSGKI-FLG-DYGSHSSED--DESIKCMGYCPQTNP-LWPDLTLQEHF 1395
Cdd:PRK09580 24 VRPGEVHAIMGPNGSGKSTLSATLAGreDYEVTGGTVeFKGkDLLELSPEDraGEGIFMAFQYPVEIPgVSNQFFLQTAL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1396 EIYGAVKGMSP---GDMKEVISRITKALDLKEH-LQKTVKKLPAGIKRKLCFALSMLG-NPQVTLLDEPSTGMDPRAKQH 1470
Cdd:PRK09580 104 NAVRSYRGQEPldrFDFQDLMEEKIALLKMPEDlLTRSVNVGFSGGEKKRNDILQMAVlEPELCILDESDSGLDIDALKI 183
|
170 180
....*....|....*....|..
gi 146134400 1471 MWRAIrTAFKNKKRAALLTTHY 1492
Cdd:PRK09580 184 VADGV-NSLRDGKRSFIIVTHY 204
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
477-646 |
1.14e-04 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 46.81 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 477 AIRISGIQKSYrkktENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGfasiyghrvsEIDEMFEARk 556
Cdd:PRK15064 319 ALEVENLTKGF----DNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSG----------TVKWSENAN- 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 557 mIGICPQ-SDINFDV-LTVEENLSILASIKGIpanniIQEVQKVLLDLDMQA--IKdNQAKKLSGGQKRKLSVGIAVLGN 632
Cdd:PRK15064 384 -IGYYAQdHAYDFENdLTLFDWMSQWRQEGDD-----EQAVRGTLGRLLFSQddIK-KSVKVLSGGEKGRMLFGKLMMQK 456
|
170
....*....|....
gi 146134400 633 PKILLLDEPTAGMD 646
Cdd:PRK15064 457 PNVLVMDEPTNHMD 470
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
1319-1361 |
1.51e-04 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 46.33 E-value: 1.51e-04
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGD 1361
Cdd:COG4615 351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDG 393
|
|
| PRK00098 |
PRK00098 |
GTPase RsgA; Reviewed |
473-527 |
1.78e-04 |
|
GTPase RsgA; Reviewed
Pssm-ID: 234631 [Multi-domain] Cd Length: 298 Bit Score: 45.58 E-value: 1.78e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 146134400 473 IGKEAIRISGiqksyrKKTENVEALRNLsfdiYEGQITALLGHSGTGKSTLMNIL 527
Cdd:PRK00098 140 IGYDVLELSA------KEGEGLDELKPL----LAGKVTVLAGQSGVGKSTLLNAL 184
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
497-671 |
1.97e-04 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 44.09 E-value: 1.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFearkMIGICPQSDINFDvLTVEEN 576
Cdd:PRK13541 16 LFDLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIAKPY----CTYIGHNLGLKLE-MTVFEN 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 577 LSILASIKgipanNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNL 656
Cdd:PRK13541 91 LKFWSEIY-----NSAETLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENRDLLNNL 165
|
170
....*....|....*..
gi 146134400 657 LKYrKANR--VTVFSTH 671
Cdd:PRK13541 166 IVM-KANSggIVLLSSH 181
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1285-1360 |
1.98e-04 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 45.83 E-value: 1.98e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 146134400 1285 EEKPAIM-VCNLHKEYDDKKDFLHSRKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGdVEPTSGKI-FLG 1360
Cdd:COG4172 270 PDAPPLLeARDLKVWFPIKRGLFRRTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLR-LIPSEGEIrFDG 346
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
1285-1360 |
5.88e-04 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 43.93 E-value: 5.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1285 EEKPAIM-VCNLHKEYD--DKKDFLHSRKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI-FLG 1360
Cdd:PRK15079 3 EGKKVLLeVADLKVHFDikDGKQWFWQPPKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVaWLG 82
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
478-665 |
5.91e-04 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 42.98 E-value: 5.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 478 IRISGIqKSYRKKTEnvealrnlsFDIYEGqITALLGHSGTGKSTLMNILcglcppsdgFASIYGHRVSEIDEMFEARKM 557
Cdd:cd03240 4 LSIRNI-RSFHERSE---------IEFFSP-LTLIVGQNGAGKTTIIEAL---------KYALTGELPPNSKGGAHDPKL 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 558 IGICP---QSDINFDV-----LTVEENLSILasikgipaNNII---QEVQKVLLdLDMqaikdnqAKKLSGGQKRKLSVG 626
Cdd:cd03240 64 IREGEvraQVKLAFENangkkYTITRSLAIL--------ENVIfchQGESNWPL-LDM-------RGRCSGGEKVLASLI 127
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 146134400 627 I------AVLGNPKILLLDEPTAGMDPCSRHIVW-NLLKYRKANRV 665
Cdd:cd03240 128 IrlalaeTFGSNCGILALDEPTTNLDEENIEESLaEIIEERKSQKN 173
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
1288-1341 |
8.32e-04 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 43.93 E-value: 8.32e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 146134400 1288 PAIMVCNLHKEYDDKKDFLHSRKTTKVATKYISFCVKKGEILGLLGPNGAGKST 1341
Cdd:PRK15134 274 PLLDVEQLQVAFPIRKGILKRTVDHNVVVKNISFTLRPGETLGLVGESGSGKST 327
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
1319-1359 |
1.05e-03 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 43.81 E-value: 1.05e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFL 1359
Cdd:PRK10522 342 INLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILL 382
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
1317-1491 |
1.09e-03 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 43.56 E-value: 1.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1317 KYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKC----MGYCPQTNPLWPDLTLQ 1392
Cdd:PRK10535 25 KGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQLrrehFGFIFQRYHLLSHLTAA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1393 EHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMw 1472
Cdd:PRK10535 105 QNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEV- 183
|
170
....*....|....*....
gi 146134400 1473 RAIRTAFKNKKRAALLTTH 1491
Cdd:PRK10535 184 MAILHQLRDRGHTVIIVTH 202
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
493-646 |
1.51e-03 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 42.32 E-value: 1.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 493 NVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGlcPPS----DGFASIYGHRVSEIDEmfEARKMIGI--CPQSDI 566
Cdd:CHL00131 19 ENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG--HPAykilEGDILFKGESILDLEP--EERAHLGIflAFQYPI 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 567 ------NFDVLTVEEN----LSILASIKGIPANNIIQEVQKvLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKIL 636
Cdd:CHL00131 95 eipgvsNADFLRLAYNskrkFQGLPELDPLEFLEIINEKLK-LVGMDPSFLSRNVNEGFSGGEKKRNEILQMALLDSELA 173
|
170
....*....|
gi 146134400 637 LLDEPTAGMD 646
Cdd:CHL00131 174 ILDETDSGLD 183
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
1330-1359 |
1.54e-03 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 42.96 E-value: 1.54e-03
10 20 30
....*....|....*....|....*....|
gi 146134400 1330 GLLGPNGAGKSTVINTLVGDVEPTSGKIFL 1359
Cdd:PRK15064 31 GLIGANGCGKSTFMKILGGDLEPSAGNVSL 60
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
1319-1357 |
1.56e-03 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 42.22 E-value: 1.56e-03
10 20 30
....*....|....*....|....*....|....*....
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKI 1357
Cdd:PRK11701 25 VSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEV 63
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
1294-1359 |
1.89e-03 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 42.26 E-value: 1.89e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146134400 1294 NLHKEYDDKKDFLHSRKTTKvATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFL 1359
Cdd:PRK11308 10 DLKKHYPVKRGLFKPERLVK-ALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYY 74
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
1325-1361 |
2.09e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 40.43 E-value: 2.09e-03
10 20 30
....*....|....*....|....*....|....*..
gi 146134400 1325 KGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGD 1361
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYID 37
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
441-536 |
2.81e-03 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 42.41 E-value: 2.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 441 SKNK---RNYKELSEGNINGNISLNEIVEPVSsEFIGKEAIRISGIQKSYRKKTenveALRNLSFDIYEGQITALLGHSG 517
Cdd:PRK11819 286 AKSKarlARYEELLSEEYQKRNETNEIFIPPG-PRLGDKVIEAENLSKSFGDRL----LIDDLSFSLPPGGIVGIIGPNG 360
|
90
....*....|....*....
gi 146134400 518 TGKSTLMNILCGLCPPSDG 536
Cdd:PRK11819 361 AGKSTLFKMITGQEQPDSG 379
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
507-647 |
3.77e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 39.66 E-value: 3.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 507 GQITALLGHSGTGKSTLMNILCGLCPPSdgfasiyGHRVSEIDemfearkmigicpqsdinfdvltveenlsilasikgi 586
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALARELGPP-------GGGVIYID------------------------------------- 37
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 146134400 587 panniIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDP 647
Cdd:smart00382 38 -----GEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDA 93
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
1319-1489 |
4.07e-03 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 41.66 E-value: 4.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLvGDVEPTsgkiflgdYGSHSSEDDESikCMGYCPQtNPLWPDLTLQEHFeIY 1398
Cdd:TIGR00954 471 LSFEVPSGNNLLICGPNGCGKSSLFRIL-GELWPV--------YGGRLTKPAKG--KLFYVPQ-RPYMTLGTLRDQI-IY 537
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 1399 gavkGMSPGDMKE------VISRITKALDLKEHLQKTV---------KKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGM 1463
Cdd:TIGR00954 538 ----PDSSEDMKRrglsdkDLEQILDNVQLTHILEREGgwsavqdwmDVLSGGEKQRIAMARLFYHKPQFAILDECTSAV 613
|
170 180
....*....|....*....|....*.
gi 146134400 1464 DPRAKQHMWRAIRtafknKKRAALLT 1489
Cdd:TIGR00954 614 SVDVEGYMYRLCR-----EFGITLFS 634
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
613-689 |
7.72e-03 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 38.88 E-value: 7.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 613 KKLSGGQKRKLSV----GIAVLGNPKILLLDEPTAGMDPCSRH-IVWNLLKYRKANRVTVFSTH---FMDEADILADRKA 684
Cdd:cd03227 76 LQLSGGEKELSALalilALASLKPRPLYILDEIDRGLDPRDGQaLAEAILEHLVKGAQVIVITHlpeLAELADKLIHIKK 155
|
....*
gi 146134400 685 VISQG 689
Cdd:cd03227 156 VITGV 160
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
497-646 |
8.04e-03 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 40.54 E-value: 8.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 497 LRNLSFDIYEGQITALLGHSGTGKSTL-MNIlcglcppsdgFASIYGHRVS--------EID-------------EMFEA 554
Cdd:NF040905 276 VDDVSLNVRRGEIVGIAGLMGAGRTELaMSV----------FGRSYGRNISgtvfkdgkEVDvstvsdaidaglaYVTED 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146134400 555 RKMIGICPQSDINfdvltveENLSiLASIKGIPANNIIQEVQKVLLDLDMQA---IK----DNQAKKLSGGQKRKLSVGI 627
Cdd:NF040905 346 RKGYGLNLIDDIK-------RNIT-LANLGKVSRRGVIDENEEIKVAEEYRKkmnIKtpsvFQKVGNLSGGNQQKVVLSK 417
|
170
....*....|....*....
gi 146134400 628 AVLGNPKILLLDEPTAGMD 646
Cdd:NF040905 418 WLFTDPDVLILDEPTRGID 436
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
1319-1359 |
8.39e-03 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 40.54 E-value: 8.39e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 146134400 1319 ISFCVKKGEILGLLGPNGAGKSTVINTLVGdVEPT---SGKIFL 1359
Cdd:NF040905 20 VNLSVREGEIHALCGENGAGKSTLMKVLSG-VYPHgsyEGEILF 62
|
|
| |
