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Conserved domains on  [gi|157909778|ref|NP_663391|]
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protein KRI1 homolog [Mus musculus]

Protein Classification

KRI1 family protein( domain architecture ID 10524403)

KRI1 family protein similar to Saccharomyces cerevisiae KRI1 (KRR1-interacting protein 1) that is required for 40S ribosome biogenesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Kri1_C pfam12936
KRI1-like family C-terminal; The yeast member of this family (Kri1p) is found to be required ...
 501-589 2.16e-39

KRI1-like family C-terminal; The yeast member of this family (Kri1p) is found to be required for 40S ribosome biogenesis in the nucleolus. This is the C-terminal domain of the family.


:

Pssm-ID: 463756  Cd Length: 89  Bit Score: 139.94  E-value: 2.16e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157909778  501 KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILSADDKELNRWCSLKKTCMYRSEQEEMQEQRVYSQKA 580
Cdd:pfam12936   1 KKLEEYVDEYYKLDYEDIIGDLPTRFKYREVSPNSFGLTAREILLADDKELNQWVSLKKLAPYRDEEKEKKDKKKYKKKA 80


                  ....*....
gi 157909778  581 QNMWKKRQI 589
Cdd:pfam12936  81 RLREWRKKV 89
Kri1 pfam05178
KRI1-like family; The yeast member of this family (Kri1p) is found to be required for 40S ...
 340-432 4.09e-19

KRI1-like family; The yeast member of this family (Kri1p) is found to be required for 40S ribosome biogenesis in the nucleolus.


:

Pssm-ID: 461569  Cd Length: 103  Bit Score: 83.08  E-value: 4.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157909778  340 ERKKREKARKQEELKQLKNLKRKEILAKLEKLRQATGNETLGLEE-------QDLEADFDPAQHDQLMQKCFGDAFYGTA 412
Cdd:pfam05178   1 ERKEEEKEEREEELKRLKKLKREEIEEKLKKIKEAAGNEGAGLKEltdeewtDLLDGDFDPDEWDRKMKKIFGEDYYAEE 80

                          90       100
                  ....*....|....*....|
gi 157909778  413 EEEKPQFEEEDGLEDDWNWD 432
Cdd:pfam05178  81 DDEEKKPTWDDDIDIGDIVP 100
 
Name Accession Description Interval E-value
Kri1_C pfam12936
KRI1-like family C-terminal; The yeast member of this family (Kri1p) is found to be required ...
 501-589 2.16e-39

KRI1-like family C-terminal; The yeast member of this family (Kri1p) is found to be required for 40S ribosome biogenesis in the nucleolus. This is the C-terminal domain of the family.


Pssm-ID: 463756  Cd Length: 89  Bit Score: 139.94  E-value: 2.16e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157909778  501 KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILSADDKELNRWCSLKKTCMYRSEQEEMQEQRVYSQKA 580
Cdd:pfam12936   1 KKLEEYVDEYYKLDYEDIIGDLPTRFKYREVSPNSFGLTAREILLADDKELNQWVSLKKLAPYRDEEKEKKDKKKYKKKA 80


                  ....*....
gi 157909778  581 QNMWKKRQI 589
Cdd:pfam12936  81 RLREWRKKV 89
Kri1 pfam05178
KRI1-like family; The yeast member of this family (Kri1p) is found to be required for 40S ...
 340-432 4.09e-19

KRI1-like family; The yeast member of this family (Kri1p) is found to be required for 40S ribosome biogenesis in the nucleolus.


Pssm-ID: 461569  Cd Length: 103  Bit Score: 83.08  E-value: 4.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157909778  340 ERKKREKARKQEELKQLKNLKRKEILAKLEKLRQATGNETLGLEE-------QDLEADFDPAQHDQLMQKCFGDAFYGTA 412
Cdd:pfam05178   1 ERKEEEKEEREEELKRLKKLKREEIEEKLKKIKEAAGNEGAGLKEltdeewtDLLDGDFDPDEWDRKMKKIFGEDYYAEE 80

                          90       100
                  ....*....|....*....|
gi 157909778  413 EEEKPQFEEEDGLEDDWNWD 432
Cdd:pfam05178  81 DDEEKKPTWDDDIDIGDIVP 100
 
Name Accession Description Interval E-value
Kri1_C pfam12936
KRI1-like family C-terminal; The yeast member of this family (Kri1p) is found to be required ...
 501-589 2.16e-39

KRI1-like family C-terminal; The yeast member of this family (Kri1p) is found to be required for 40S ribosome biogenesis in the nucleolus. This is the C-terminal domain of the family.


Pssm-ID: 463756  Cd Length: 89  Bit Score: 139.94  E-value: 2.16e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157909778  501 KTFEEYLDEYYRLDYEDIIDDLPCRFKYRTVVPCDFGLSTEEILSADDKELNRWCSLKKTCMYRSEQEEMQEQRVYSQKA 580
Cdd:pfam12936   1 KKLEEYVDEYYKLDYEDIIGDLPTRFKYREVSPNSFGLTAREILLADDKELNQWVSLKKLAPYRDEEKEKKDKKKYKKKA 80


                  ....*....
gi 157909778  581 QNMWKKRQI 589
Cdd:pfam12936  81 RLREWRKKV 89
Kri1 pfam05178
KRI1-like family; The yeast member of this family (Kri1p) is found to be required for 40S ...
 340-432 4.09e-19

KRI1-like family; The yeast member of this family (Kri1p) is found to be required for 40S ribosome biogenesis in the nucleolus.


Pssm-ID: 461569  Cd Length: 103  Bit Score: 83.08  E-value: 4.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157909778  340 ERKKREKARKQEELKQLKNLKRKEILAKLEKLRQATGNETLGLEE-------QDLEADFDPAQHDQLMQKCFGDAFYGTA 412
Cdd:pfam05178   1 ERKEEEKEEREEELKRLKKLKREEIEEKLKKIKEAAGNEGAGLKEltdeewtDLLDGDFDPDEWDRKMKKIFGEDYYAEE 80

                          90       100
                  ....*....|....*....|
gi 157909778  413 EEEKPQFEEEDGLEDDWNWD 432
Cdd:pfam05178  81 DDEEKKPTWDDDIDIGDIVP 100
Nop53 pfam07767
Nop53 (60S ribosomal biogenesis); This nucleolar family of proteins are involved in 60S ...
 329-374 5.65e-03

Nop53 (60S ribosomal biogenesis); This nucleolar family of proteins are involved in 60S ribosomal biogenesis. They are specifically involved in the processing beyond the 27S stage of 25S rRNA maturation. This family contains sequences that bear similarity to the glioma tumour suppressor candidate region gene 2 protein (p60). This protein has been found to interact with herpes simplex type 1 regulatory proteins.


Pssm-ID: 462259 [Multi-domain]  Cd Length: 353  Bit Score: 39.59  E-value: 5.65e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 157909778  329 ERRKEKREETRERKKREKARKQEELKQLKNLK--RKEILAKLEKLRQA 374
Cdd:pfam07767 244 QRNKEKRRKEEEREAKEEKALKKKLAQLERLKeiAKEIAEKEKEREEK 291
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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