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Conserved domains on  [gi|17558492|ref|NP_504297|]
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Abhydrolase domain-containing protein abhd-5.2 [Caenorhabditis elegans]

Protein Classification

alpha/beta hydrolase domain-containing protein( domain architecture ID 1005082)

alpha/beta hydrolase (abhydrolase) domain-containing protein

CATH:  3.40.50.1820
EC:  3.-.-.-
Gene Ontology:  GO:0016787
PubMed:  19508187|12369917

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PLN02894 super family cl30398
hydrolase, alpha/beta fold family protein
 68-413 3.20e-46

hydrolase, alpha/beta fold family protein


The actual alignment was detected with superfamily member PLN02894:

Pssm-ID: 215484 [Multi-domain]  Cd Length: 402  Bit Score: 164.70  E-value: 3.20e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   68 EIRAFQSEGHLHLKYISLIIAMMAETAvvTSRSWFPYFS--CPSKSQRLAEAEGRILSALGIKYLARLIQI----P---- 137
Cdd:PLN02894   4 QLRGHEIPGHGAASSAAASAAASAETS--RTRSLWPSPLrwIPTSTDHIIAAEKRLLSLVKTPYVQEQVNIgsgpPgskv 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  138 --FKNTE-----ISTITVNCESEQPivkakyPIVLIHGFGAGVALWGSAIKRLAQFQTVHAFDLPGFGRSSRPKFS-SDP 209
Cdd:PLN02894  82 rwFRSASneprfINTVTFDSKEDAP------TLVMVHGYGASQGFFFRNFDALASRFRVIAIDQLGWGGSSRPDFTcKST 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  210 ETAETEMIDSIEQWRDKMNLEKMNLVGHSFGGYLATSYALKYPKRVENLILADPWGFN---EMDPEFAQKLTSRQK---- 282
Cdd:PLN02894 156 EETEAWFIDSFEEWRKAKNLSNFILLGHSFGGYVAAKYALKHPEHVQHLILVGPAGFSsesDDKSEWLTKFRATWKgavl 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  283 NIFWViQQFNPLAVLRLVGGYGPSLVRRL----------RPDLALKYSEDVYDYIYLANSRDPTGEEVFKCLSENLGWAK 352
Cdd:PLN02894 236 NHLWE-SNFTPQKIIRGLGPWGPNLVRRYttarfgahstGDILSEEESKLLTDYVYHTLAAKASGELCLKYIFSFGAFAR 314

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17558492  353 QPMSKRFHELdnTVPVTFIHGERSWIDWRTTRRLFGELEH-VESHIMDSAGHHVYADDADKF 413
Cdd:PLN02894 315 KPLLESASEW--KVPTTFIYGRHDWMNYEGAVEARKRMKVpCEIIRVPQGGHFVFLDNPSGF 374
 
Name Accession Description Interval E-value
PLN02894 PLN02894
hydrolase, alpha/beta fold family protein
 68-413 3.20e-46

hydrolase, alpha/beta fold family protein


Pssm-ID: 215484 [Multi-domain]  Cd Length: 402  Bit Score: 164.70  E-value: 3.20e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   68 EIRAFQSEGHLHLKYISLIIAMMAETAvvTSRSWFPYFS--CPSKSQRLAEAEGRILSALGIKYLARLIQI----P---- 137
Cdd:PLN02894   4 QLRGHEIPGHGAASSAAASAAASAETS--RTRSLWPSPLrwIPTSTDHIIAAEKRLLSLVKTPYVQEQVNIgsgpPgskv 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  138 --FKNTE-----ISTITVNCESEQPivkakyPIVLIHGFGAGVALWGSAIKRLAQFQTVHAFDLPGFGRSSRPKFS-SDP 209
Cdd:PLN02894  82 rwFRSASneprfINTVTFDSKEDAP------TLVMVHGYGASQGFFFRNFDALASRFRVIAIDQLGWGGSSRPDFTcKST 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  210 ETAETEMIDSIEQWRDKMNLEKMNLVGHSFGGYLATSYALKYPKRVENLILADPWGFN---EMDPEFAQKLTSRQK---- 282
Cdd:PLN02894 156 EETEAWFIDSFEEWRKAKNLSNFILLGHSFGGYVAAKYALKHPEHVQHLILVGPAGFSsesDDKSEWLTKFRATWKgavl 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  283 NIFWViQQFNPLAVLRLVGGYGPSLVRRL----------RPDLALKYSEDVYDYIYLANSRDPTGEEVFKCLSENLGWAK 352
Cdd:PLN02894 236 NHLWE-SNFTPQKIIRGLGPWGPNLVRRYttarfgahstGDILSEEESKLLTDYVYHTLAAKASGELCLKYIFSFGAFAR 314

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17558492  353 QPMSKRFHELdnTVPVTFIHGERSWIDWRTTRRLFGELEH-VESHIMDSAGHHVYADDADKF 413
Cdd:PLN02894 315 KPLLESASEW--KVPTTFIYGRHDWMNYEGAVEARKRMKVpCEIIRVPQGGHFVFLDNPSGF 374
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 162-418 2.11e-33

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 125.11  E-value: 2.11e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492 162 PIVLIHGFGAGVALWGSAIKRLAQFQTVHAFDLPGFGRSSRPKFSSDPETaeteMIDSIEQWRDKMNLEKMNLVGHSFGG 241
Cdd:COG0596  25 PVVLLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGHGRSDKPAGGYTLDD----LADDLAALLDALGLERVVLVGHSMGG 100

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492 242 YLATSYALKYPKRVENLILADpwgfnemdpEFAQKLtsrqknifwviqqfnpLAVLRLVGGYGPSLVRRLRpdlalkyse 321
Cdd:COG0596 101 MVALELAARHPERVAGLVLVD---------EVLAAL----------------AEPLRRPGLAPEALAALLR--------- 146

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492 322 dvydyiylansrdptgeevfkclsenlGWAKQPMSKRFHELdnTVPVTFIHGERS-WIDWRTTRRLFGELEHVESHIMDS 400
Cdd:COG0596 147 ---------------------------ALARTDLRERLARI--TVPTLVIWGEKDpIVPPALARRLAELLPNAELVVLPG 197

                       250
                ....*....|....*...
gi 17558492 401 AGHHVYADDADKFVQLVI 418
Cdd:COG0596 198 AGHFPPLEQPEAFAAALR 215
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 161-410 1.24e-30

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 118.38  E-value: 1.24e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   161 YPIVLIHGFGAGVALWGSAIKRLAQF-QTVHAFDLPGFGRSSRPKFSSDPETAEteMIDSIEQWRDKMNLEKMNLVGHSF 239
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALARDgFRVIALDLRGFGKSSRPKAQDDYRTDD--LAEDLEYILEALGLEKVNLVGHSM 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   240 GGYLATSYALKYPKRVENLILADPWG-----FNEMDPEFAQKLTSRQKNIFWVIQ-QFNPLAVLRLVGGYGPSLVRRLRP 313
Cdd:pfam00561  79 GGLIALAYAAKYPDRVKALVLLGALDpphelDEADRFILALFPGFFDGFVADFAPnPLGRLVAKLLALLLLRLRLLKALP 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   314 DLALKYSEDVYDYIylansrdptGEEVFKCLSENLGWAKQPMSKRFHELDntVPVTFIHGERSWI-DWRTTRRLFGELEH 392
Cdd:pfam00561 159 LLNKRFPSGDYALA---------KSLVTGALLFIETWSTELRAKFLGRLD--EPTLIIWGDQDPLvPPQALEKLAQLFPN 227

                         250
                  ....*....|....*...
gi 17558492   393 VESHIMDSAGHHVYADDA 410
Cdd:pfam00561 228 ARLVVIPDAGHFAFLEGP 245
pro_imino_pep_2 TIGR01250
proline-specific peptidase, Bacillus coagulans-type subfamily; This model describes a ...
 160-418 3.63e-15

proline-specific peptidase, Bacillus coagulans-type subfamily; This model describes a subfamily of the alpha/beta fold family of hydrolases. Characterized members include prolinases (Pro-Xaa dipeptidase, EC 3.4.13.8), prolyl aminopeptidases (EC 3.4.11.5), and a leucyl aminopeptidase


Pssm-ID: 188121 [Multi-domain]  Cd Length: 289  Bit Score: 75.49  E-value: 3.63e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   160 KYPIVLIHGFGAGVALWGSAIKRLAQFQ--TVHAFDLPGFGRSSRPKFSsDPETAETE-MIDSIEQWRDKMNLEKMNLVG 236
Cdd:TIGR01250  25 KIKLLLLHGGPGMSHEYLENLRELLKEEgrEVIMYDQLGCGYSDQPDDS-DEELWTIDyFVDELEEVREKLGLDKFYLLG 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   237 HSFGGYLATSYALKYPKRVENLILADPwgfneMD--PEFAQKLTSRQKNIfwviqqfnPLAVL----------------- 297
Cdd:TIGR01250 104 HSWGGMLAQEYALKYGQHLKGLIISSM-----LDsaPEYVKELNRLRKEL--------PPEVRaaikrceasgdydnpey 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   298 -RLVGGYGPSLVRRLR--PDlALKYSE-----DVYDYIYLANSRDPTGeevfkclseNLgwAKQPMSKRFHELdnTVPVT 369
Cdd:TIGR01250 171 qEAVEVFYHHLLCRLRkwPE-ALKHLKsggntNVYNIMQGPNEFTITG---------NL--KDWDITDKLSEI--KVPTL 236

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 17558492   370 FIHGERSWIDWRTTRRLFGELEHVESHIMDSAGHHVYADDADKFVQLVI 418
Cdd:TIGR01250 237 LTVGEFDTMTPEAAREMQELIAGSRLVVFPDGSHMTMIEDPEVYFKLLS 285
 
Name Accession Description Interval E-value
PLN02894 PLN02894
hydrolase, alpha/beta fold family protein
 68-413 3.20e-46

hydrolase, alpha/beta fold family protein


Pssm-ID: 215484 [Multi-domain]  Cd Length: 402  Bit Score: 164.70  E-value: 3.20e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   68 EIRAFQSEGHLHLKYISLIIAMMAETAvvTSRSWFPYFS--CPSKSQRLAEAEGRILSALGIKYLARLIQI----P---- 137
Cdd:PLN02894   4 QLRGHEIPGHGAASSAAASAAASAETS--RTRSLWPSPLrwIPTSTDHIIAAEKRLLSLVKTPYVQEQVNIgsgpPgskv 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  138 --FKNTE-----ISTITVNCESEQPivkakyPIVLIHGFGAGVALWGSAIKRLAQFQTVHAFDLPGFGRSSRPKFS-SDP 209
Cdd:PLN02894  82 rwFRSASneprfINTVTFDSKEDAP------TLVMVHGYGASQGFFFRNFDALASRFRVIAIDQLGWGGSSRPDFTcKST 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  210 ETAETEMIDSIEQWRDKMNLEKMNLVGHSFGGYLATSYALKYPKRVENLILADPWGFN---EMDPEFAQKLTSRQK---- 282
Cdd:PLN02894 156 EETEAWFIDSFEEWRKAKNLSNFILLGHSFGGYVAAKYALKHPEHVQHLILVGPAGFSsesDDKSEWLTKFRATWKgavl 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  283 NIFWViQQFNPLAVLRLVGGYGPSLVRRL----------RPDLALKYSEDVYDYIYLANSRDPTGEEVFKCLSENLGWAK 352
Cdd:PLN02894 236 NHLWE-SNFTPQKIIRGLGPWGPNLVRRYttarfgahstGDILSEEESKLLTDYVYHTLAAKASGELCLKYIFSFGAFAR 314

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17558492  353 QPMSKRFHELdnTVPVTFIHGERSWIDWRTTRRLFGELEH-VESHIMDSAGHHVYADDADKF 413
Cdd:PLN02894 315 KPLLESASEW--KVPTTFIYGRHDWMNYEGAVEARKRMKVpCEIIRVPQGGHFVFLDNPSGF 374
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 162-418 2.11e-33

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 125.11  E-value: 2.11e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492 162 PIVLIHGFGAGVALWGSAIKRLAQFQTVHAFDLPGFGRSSRPKFSSDPETaeteMIDSIEQWRDKMNLEKMNLVGHSFGG 241
Cdd:COG0596  25 PVVLLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGHGRSDKPAGGYTLDD----LADDLAALLDALGLERVVLVGHSMGG 100

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492 242 YLATSYALKYPKRVENLILADpwgfnemdpEFAQKLtsrqknifwviqqfnpLAVLRLVGGYGPSLVRRLRpdlalkyse 321
Cdd:COG0596 101 MVALELAARHPERVAGLVLVD---------EVLAAL----------------AEPLRRPGLAPEALAALLR--------- 146

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492 322 dvydyiylansrdptgeevfkclsenlGWAKQPMSKRFHELdnTVPVTFIHGERS-WIDWRTTRRLFGELEHVESHIMDS 400
Cdd:COG0596 147 ---------------------------ALARTDLRERLARI--TVPTLVIWGEKDpIVPPALARRLAELLPNAELVVLPG 197

                       250
                ....*....|....*...
gi 17558492 401 AGHHVYADDADKFVQLVI 418
Cdd:COG0596 198 AGHFPPLEQPEAFAAALR 215
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 161-410 1.24e-30

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 118.38  E-value: 1.24e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   161 YPIVLIHGFGAGVALWGSAIKRLAQF-QTVHAFDLPGFGRSSRPKFSSDPETAEteMIDSIEQWRDKMNLEKMNLVGHSF 239
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALARDgFRVIALDLRGFGKSSRPKAQDDYRTDD--LAEDLEYILEALGLEKVNLVGHSM 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   240 GGYLATSYALKYPKRVENLILADPWG-----FNEMDPEFAQKLTSRQKNIFWVIQ-QFNPLAVLRLVGGYGPSLVRRLRP 313
Cdd:pfam00561  79 GGLIALAYAAKYPDRVKALVLLGALDpphelDEADRFILALFPGFFDGFVADFAPnPLGRLVAKLLALLLLRLRLLKALP 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   314 DLALKYSEDVYDYIylansrdptGEEVFKCLSENLGWAKQPMSKRFHELDntVPVTFIHGERSWI-DWRTTRRLFGELEH 392
Cdd:pfam00561 159 LLNKRFPSGDYALA---------KSLVTGALLFIETWSTELRAKFLGRLD--EPTLIIWGDQDPLvPPQALEKLAQLFPN 227

                         250
                  ....*....|....*...
gi 17558492   393 VESHIMDSAGHHVYADDA 410
Cdd:pfam00561 228 ARLVVIPDAGHFAFLEGP 245
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
146-264 4.65e-18

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 82.74  E-value: 4.65e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492 146 ITVNCESEQPIVKAKYPIVLIHGFGAGVALWGSAIKRLAQ--FqTVHAFDLPGFGRSSRPKfsSDPETAEtEMIDSIEQW 223
Cdd:COG2267  14 LRLRGRRWRPAGSPRGTVVLVHGLGEHSGRYAELAEALAAagY-AVLAFDLRGHGRSDGPR--GHVDSFD-DYVDDLRAA 89

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 17558492 224 RDKMNLE---KMNLVGHSFGGYLATSYALKYPKRVENLILADPW 264
Cdd:COG2267  90 LDALRARpglPVVLLGHSMGGLIALLYAARYPDRVAGLVLLAPA 133
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 162-273 3.29e-16

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 79.60  E-value: 3.29e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  162 PIVLIHGFGAGVALWGSAIKRLAQFQTVHAFDLPGFGRSSRPKFSSDPEtaetEMIDSIEQWRDKMNLEKMNLVGHSFGG 241
Cdd:PRK14875 133 PVVLIHGFGGDLNNWLFNHAALAAGRPVIALDLPGHGASSKAVGAGSLD----ELAAAVLAFLDALGIERAHLVGHSMGG 208

                         90       100       110
                 ....*....|....*....|....*....|...
gi 17558492  242 YLATSYALKYPKRVENLILADPWGFN-EMDPEF 273
Cdd:PRK14875 209 AVALRLAARAPQRVASLTLIAPAGLGpEINGDY 241
pro_imino_pep_2 TIGR01250
proline-specific peptidase, Bacillus coagulans-type subfamily; This model describes a ...
 160-418 3.63e-15

proline-specific peptidase, Bacillus coagulans-type subfamily; This model describes a subfamily of the alpha/beta fold family of hydrolases. Characterized members include prolinases (Pro-Xaa dipeptidase, EC 3.4.13.8), prolyl aminopeptidases (EC 3.4.11.5), and a leucyl aminopeptidase


Pssm-ID: 188121 [Multi-domain]  Cd Length: 289  Bit Score: 75.49  E-value: 3.63e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   160 KYPIVLIHGFGAGVALWGSAIKRLAQFQ--TVHAFDLPGFGRSSRPKFSsDPETAETE-MIDSIEQWRDKMNLEKMNLVG 236
Cdd:TIGR01250  25 KIKLLLLHGGPGMSHEYLENLRELLKEEgrEVIMYDQLGCGYSDQPDDS-DEELWTIDyFVDELEEVREKLGLDKFYLLG 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   237 HSFGGYLATSYALKYPKRVENLILADPwgfneMD--PEFAQKLTSRQKNIfwviqqfnPLAVL----------------- 297
Cdd:TIGR01250 104 HSWGGMLAQEYALKYGQHLKGLIISSM-----LDsaPEYVKELNRLRKEL--------PPEVRaaikrceasgdydnpey 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   298 -RLVGGYGPSLVRRLR--PDlALKYSE-----DVYDYIYLANSRDPTGeevfkclseNLgwAKQPMSKRFHELdnTVPVT 369
Cdd:TIGR01250 171 qEAVEVFYHHLLCRLRkwPE-ALKHLKsggntNVYNIMQGPNEFTITG---------NL--KDWDITDKLSEI--KVPTL 236

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 17558492   370 FIHGERSWIDWRTTRRLFGELEHVESHIMDSAGHHVYADDADKFVQLVI 418
Cdd:TIGR01250 237 LTVGEFDTMTPEAAREMQELIAGSRLVVFPDGSHMTMIEDPEVYFKLLS 285
bioH TIGR01738
pimelyl-[acyl-carrier protein] methyl ester esterase; This CoA-binding enzyme is required for ...
 163-418 1.17e-14

pimelyl-[acyl-carrier protein] methyl ester esterase; This CoA-binding enzyme is required for the production of pimeloyl-coenzyme A, the substrate of the BioF protein early in the biosynthesis of biotin. Its exact function is unknown, but is proposed in ref 2. This enzyme belongs to the alpha/beta hydrolase fold family (pfam00561). Members of this family are restricted to the Proteobacteria. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273783 [Multi-domain]  Cd Length: 245  Bit Score: 73.31  E-value: 1.17e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   163 IVLIHGFGAGVALWGSAIKRLAQFQTVHAFDLPGFGRSSRPKFSSDPETAET--EMIDSIEQWrdkmnlekmnlVGHSFG 240
Cdd:TIGR01738   7 LVLIHGWGMNAEVFRCLDEELSAHFTLHLVDLPGHGRSRGFGPLSLADMAEAiaAQAPDPAIW-----------LGWSLG 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   241 GYLATSYALKYPKRVENLILA---------DPWGFNEMDPEFAQKLTSRQKNIFWVIQQFnpLAVLRLVGGYGPSLVRRL 311
Cdd:TIGR01738  76 GLVALHIAATHPDRVRALVTVasspcfsarEDWPEGIKPDVLTGFQQQLSDDYQRTIERF--LALQTLGTPTARQDARAL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   312 RPDLAlkysedvydyiylansRDPTGEEvfKCLSENLGWAKQPMSKrfHELDN-TVPVTFIHGERSWI-DWRTTRRLFGE 389
Cdd:TIGR01738 154 KQTLL----------------ARPTPNV--QVLQAGLEILATVDLR--QPLQNiSVPFLRLYGYLDGLvPAKVVPMLDKL 213

                         250       260
                  ....*....|....*....|....*....
gi 17558492   390 LEHVESHIMDSAGHHVYADDADKFVQLVI 418
Cdd:TIGR01738 214 APHSELYIFAKAAHAPFLSHAEAFCALLV 242
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 163-416 2.19e-14

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 71.74  E-value: 2.19e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   163 IVLIHGFGAGVALWGSAIKRLAqfqTVHAFDLPGFGRSSRPKFSSDPETAETEMIDSIEQWRDKMnlekmnLVGHSFGGY 242
Cdd:pfam12697   1 VVLVHGAGLSAAPLAALLAAGV---AVLAPDLPGHGSSSPPPLDLADLADLAALLDELGAARPVV------LVGHSLGGA 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   243 LATsYALKYPKRVENLI--LADPWGFNEMDPEFAQKLTSRQKNIFWVIQQFNPLAVLRlvggygpslvrrlRPDLALKYS 320
Cdd:pfam12697  72 VAL-AAAAAALVVGVLVapLAAPPGLLAALLALLARLGAALAAPAWLAAESLARGFLD-------------DLPADAEWA 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   321 EDVYDYIYLANSRDPTGEEvfkclsenlGWAKQPmskrfheldntVPVTFIHGERSWIDwRTTRRLFGELEHVESHIMDS 400
Cdd:pfam12697 138 AALARLAALLAALALLPLA---------AWRDLP-----------VPVLVLAEEDRLVP-ELAQRLLAALAGARLVVLPG 196

                         250
                  ....*....|....*.
gi 17558492   401 AGHHVYaDDADKFVQL 416
Cdd:pfam12697 197 AGHLPL-DDPEEVAEA 211
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 158-259 3.86e-14

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 68.32  E-value: 3.86e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492 158 KAKYPIVLIHGFGAGVALWGSAIKRL-AQFQTVHAFDLPGFGRSSRpkfssdpETAEtEMIDSIEQWRDKMNLEKMNLVG 236
Cdd:COG1075   3 ATRYPVVLVHGLGGSAASWAPLAPRLrAAGYPVYALNYPSTNGSIE-------DSAE-QLAAFVDAVLAATGAEKVDLVG 74

                        90       100
                ....*....|....*....|....*
gi 17558492 237 HSFGGYLATSYA--LKYPKRVENLI 259
Cdd:COG1075  75 HSMGGLVARYYLkrLGGAAKVARVV 99
PLN02578 PLN02578
hydrolase
 162-341 8.05e-14

hydrolase


Pssm-ID: 215315 [Multi-domain]  Cd Length: 354  Bit Score: 72.57  E-value: 8.05e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  162 PIVLIHGFGAGVALWGSAIKRLAQFQTVHAFDLPGFGRSSRPKFSSDPETAETEMIDSIEQwrdkMNLEKMNLVGHSFGG 241
Cdd:PLN02578  88 PIVLIHGFGASAFHWRYNIPELAKKYKVYALDLLGFGWSDKALIEYDAMVWRDQVADFVKE----VVKEPAVLVGNSLGG 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  242 YLATSYALKYPKRVENLILADPWG-FNEMDPEFAQKLTSRQKNIFWVIqqFNPL--AVLRLVGGY------GPSlvrRLR 312
Cdd:PLN02578 164 FTALSTAVGYPELVAGVALLNSAGqFGSESREKEEAIVVEETVLTRFV--VKPLkeWFQRVVLGFlfwqakQPS---RIE 238

                        170       180       190
                 ....*....|....*....|....*....|....
gi 17558492  313 PDLALKY--SEDVYDYIY---LANSRDPTGEEVF 341
Cdd:PLN02578 239 SVLKSVYkdKSNVDDYLVesiTEPAADPNAGEVY 272
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
154-422 1.27e-11

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 64.58  E-value: 1.27e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492 154 QPIV--KAKYPIVLIHGFGAGVALWGSAIKRLAQFQ-TVHAFDLPGFGRSsrpkfssdPEtaetEMID-SIEQWRD---- 225
Cdd:COG1647   7 EPFFleGGRKGVLLLHGFTGSPAEMRPLAEALAKAGyTVYAPRLPGHGTS--------PE----DLLKtTWEDWLEdvee 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492 226 -----KMNLEKMNLVGHSFGGYLATSYALKYPkRVENLILADPwgfnemdpefAQKLTSRQKNIFWVIQQFNPlavlrlv 300
Cdd:COG1647  75 ayeilKAGYDKVIVIGLSMGGLLALLLAARYP-DVAGLVLLSP----------ALKIDDPSAPLLPLLKYLAR------- 136

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492 301 ggygpsLVRRLRPDLAL-KYSEDVYDYIYLansrdPTGEEVFKCLSEnlgwakqpMSKRFHELdnTVPVTFIHGER-SWI 378
Cdd:COG1647 137 ------SLRGIGSDIEDpEVAEYAYDRTPL-----RALAELQRLIRE--------VRRDLPKI--TAPTLIIQSRKdEVV 195

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*..
gi 17558492 379 DWRTTRRLFGEL--EHVESHIMDSAGHHVYAD-DADKFVQLVIGSLK 422
Cdd:COG1647 196 PPESARYIYERLgsPDKELVWLEDSGHVITLDkDREEVAEEILDFLE 242
PRK03592 PRK03592
haloalkane dehalogenase; Provisional
 162-298 5.77e-11

haloalkane dehalogenase; Provisional


Pssm-ID: 235135  Cd Length: 295  Bit Score: 63.09  E-value: 5.77e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  162 PIVLIHGFGAGVALWGSAIKRLAQFQTVHAFDLPGFGRSSRPkfssDPETAETEMIDSIEQWRDKMNLEKMNLVGHSFGG 241
Cdd:PRK03592  29 PIVFLHGNPTSSYLWRNIIPHLAGLGRCLAPDLIGMGASDKP----DIDYTFADHARYLDAWFDALGLDDVVLVGHDWGS 104

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17558492  242 YLATSYALKYPKRVENLILADP------WG-FNEMDPEFAQKLTSR--------QKNIFwvIQQFNPLAVLR 298
Cdd:PRK03592 105 ALGFDWAARHPDRVRGIAFMEAivrpmtWDdFPPAVRELFQALRSPgegeemvlEENVF--IERVLPGSILR 174
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 163-403 1.34e-09

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 58.38  E-value: 1.34e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   163 IVLIHGFG------AGVAlwgsaiKRLAQFQ-TVHAFDLPGFGRSsrpkfssDPETAEtemIDSIEQWRDKMNL------ 229
Cdd:pfam12146   7 VVLVHGLGehsgryAHLA------DALAAQGfAVYAYDHRGHGRS-------DGKRGH---VPSFDDYVDDLDTfvdkir 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   230 -----EKMNLVGHSFGGYLATSYALKYPKRVENLILADPWgfnemdpefaqkltsrqkniFWVIQQFNPLaVLRLVGGyg 304
Cdd:pfam12146  71 eehpgLPLFLLGHSMGGLIAALYALRYPDKVDGLILSAPA--------------------LKIKPYLAPP-ILKLLAK-- 127

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492   305 psLVRRLRPDLALKYSEDVyDYIylanSRDPtgEEVFKCLSENL-------GWAKQPMS------KRFHELdnTVPVTFI 371
Cdd:pfam12146 128 --LLGKLFPRLRVPNNLLP-DSL----SRDP--EVVAAYAADPLvhggisaRTLYELLDagerllRRAAAI--TVPLLLL 196

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 17558492   372 HGERSWI-DWRTTRRLFGEL--EHVESHIMDSAGH 403
Cdd:pfam12146 197 HGGADRVvDPAGSREFYERAgsTDKTLKLYPGLYH 231
PLN02679 PLN02679
hydrolase, alpha/beta fold family protein
 162-240 1.93e-09

hydrolase, alpha/beta fold family protein


Pssm-ID: 178283 [Multi-domain]  Cd Length: 360  Bit Score: 59.08  E-value: 1.93e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  162 PIVLIHGFGAGVALWGSAIKRLAQFQTVHAFDLPGFGRSSRP-KFSSDPETAETEMIDSIEQWRDKMNLekmnLVGHSFG 240
Cdd:PLN02679  90 PVLLVHGFGASIPHWRRNIGVLAKNYTVYAIDLLGFGASDKPpGFSYTMETWAELILDFLEEVVQKPTV----LIGNSVG 165
PRK10349 PRK10349
pimeloyl-ACP methyl ester esterase BioH;
163-259 1.26e-08

pimeloyl-ACP methyl ester esterase BioH;


Pssm-ID: 137836 [Multi-domain]  Cd Length: 256  Bit Score: 55.79  E-value: 1.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  163 IVLIHGFGAGVALWGSAIKRLAQFQTVHAFDLPGFGRSSRPKFSSDPETAETEMIDSIEQ--WrdkmnlekmnlVGHSFG 240
Cdd:PRK10349  16 LVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALSLADMAEAVLQQAPDKaiW-----------LGWSLG 84

                         90
                 ....*....|....*....
gi 17558492  241 GYLATSYALKYPKRVENLI 259
Cdd:PRK10349  85 GLVASQIALTHPERVQALV 103
PLN03087 PLN03087
BODYGUARD 1 domain containing hydrolase; Provisional
 153-263 4.10e-08

BODYGUARD 1 domain containing hydrolase; Provisional


Pssm-ID: 215567  Cd Length: 481  Bit Score: 55.20  E-value: 4.10e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  153 EQPI-VKAKYPIVLIHGFGAGVALW---------GSAIKRLAQFqtvhAFDLPGFGRSSRPKFSSDPETAETEMIDS--I 220
Cdd:PLN03087 193 QQPKdNKAKEDVLFIHGFISSSAFWtetlfpnfsDAAKSTYRLF----AVDLLGFGRSPKPADSLYTLREHLEMIERsvL 268

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 17558492  221 EQWRdkmnLEKMNLVGHSFGGYLATSYALKYPKRVENLILADP 263
Cdd:PLN03087 269 ERYK----VKSFHIVAHSLGCILALALAVKHPGAVKSLTLLAP 307
PLN02824 PLN02824
hydrolase, alpha/beta fold family protein
 162-263 1.82e-07

hydrolase, alpha/beta fold family protein


Pssm-ID: 178419 [Multi-domain]  Cd Length: 294  Bit Score: 52.43  E-value: 1.82e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  162 PIVLIHGFGAGVALWGSAIKRLAQFQTVHAFDLPGFGRSSRPkfssDPETAETEMIDSIEQWRDKMN---LEKMN----L 234
Cdd:PLN02824  31 ALVLVHGFGGNADHWRKNTPVLAKSHRVYAIDLLGYGYSDKP----NPRSAPPNSFYTFETWGEQLNdfcSDVVGdpafV 106

                         90       100
                 ....*....|....*....|....*....
gi 17558492  235 VGHSFGGYLATSYALKYPKRVENLILADP 263
Cdd:PLN02824 107 ICNSVGGVVGLQAAVDAPELVRGVMLINI 135
PLN03084 PLN03084
alpha/beta hydrolase fold protein; Provisional
 162-421 1.06e-06

alpha/beta hydrolase fold protein; Provisional


Pssm-ID: 178633  Cd Length: 383  Bit Score: 50.65  E-value: 1.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  162 PIVLIHGFGAGVALWGSAIKRLAQFQTVHAFDLPGFGRSSRPKFSSDPETAETEMIDSIEQWRDKMNLEKMNLVGHSFGG 241
Cdd:PLN03084 129 PVLLIHGFPSQAYSYRKVLPVLSKNYHAIAFDWLGFGFSDKPQPGYGFNYTLDEYVSSLESLIDELKSDKVSLVVQGYFS 208

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  242 YLATSYALKYPKRVENLILADPwgfnEMDPEFAqKLTSRQ---KNIFW--VIQQfNPL-AVLRLVGGYGPSLVRRlrpdl 315
Cdd:PLN03084 209 PPVVKYASAHPDKIKKLILLNP----PLTKEHA-KLPSTLsefSNFLLgeIFSQ-DPLrASDKALTSCGPYAMKE----- 277

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  316 alkysED--VYDYIYLAN-SRDPTGEEVFKCLSENLGWAKQPMSKRFHELDNTVPVTFIHGERS-WIDWRTTRRLFGELE 391
Cdd:PLN03084 278 -----DDamVYRRPYLTSgSSGFALNAISRSMKKELKKYIEEMRSILTDKNWKTPITVCWGLRDrWLNYDGVEDFCKSSQ 352

                        250       260       270
                 ....*....|....*....|....*....|..
gi 17558492  392 H--VEshiMDSAGHHVYADDADKFVQLVIGSL 421
Cdd:PLN03084 353 HklIE---LPMAGHHVQEDCGEELGGIISGIL 381
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
155-255 1.70e-06

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 48.86  E-value: 1.70e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492 155 PIVKAKYP-IVLIHGFGAGVAL-WGSAIKRLAQ--FQTVhAFDLPGFGRSSRpkfssdpETAETEMIDSIE--QW---RD 225
Cdd:COG1506  17 PADGKKYPvVVYVHGGPGSRDDsFLPLAQALASrgYAVL-APDYRGYGESAG-------DWGGDEVDDVLAaiDYlaaRP 88

                        90       100       110
                ....*....|....*....|....*....|
gi 17558492 226 KMNLEKMNLVGHSFGGYLATSYALKYPKRV 255
Cdd:COG1506  89 YVDPDRIGIYGHSYGGYMALLAAARHPDRF 118
PRK10673 PRK10673
esterase;
162-262 4.02e-06

esterase;


Pssm-ID: 182637 [Multi-domain]  Cd Length: 255  Bit Score: 48.19  E-value: 4.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  162 PIVLIHG-FGAGVALwGSAIKRLAQFQTVHAFDLPGFGRSSRpkfssDPETAETEMIDSIEQWRDKMNLEKMNLVGHSFG 240
Cdd:PRK10673  18 PIVLVHGlFGSLDNL-GVLARDLVNDHDIIQVDMRNHGLSPR-----DPVMNYPAMAQDLLDTLDALQIEKATFIGHSMG 91

                         90       100
                 ....*....|....*....|..
gi 17558492  241 GYLATSYALKYPKRVENLILAD 262
Cdd:PRK10673  92 GKAVMALTALAPDRIDKLVAID 113
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 158-277 7.93e-06

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 47.22  E-value: 7.93e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492 158 KAKYPIVLI-HGFGAGVALWGSAIKRLAQ--FQTVhAFDLPGFGRSS-RPKFSSDPETAETE-MIDSIEQwRDKMNLEKM 232
Cdd:COG1073  34 SKKYPAVVVaHGNGGVKEQRALYAQRLAElgFNVL-AFDYRGYGESEgEPREEGSPERRDARaAVDYLRT-LPGVDPERI 111

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*
gi 17558492 233 NLVGHSFGGYLATSYALKYPkRVENLILADPwgFNEMDPEFAQKL 277
Cdd:COG1073 112 GLLGISLGGGYALNAAATDP-RVKAVILDSP--FTSLEDLAAQRA 153
PRK00870 PRK00870
haloalkane dehalogenase; Provisional
 162-333 9.17e-05

haloalkane dehalogenase; Provisional


Pssm-ID: 179147 [Multi-domain]  Cd Length: 302  Bit Score: 44.19  E-value: 9.17e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  162 PIVLIHGFGAGVALWGSAIKRLAQF-QTVHAFDLPGFGRSSRPKFSSDpETAETEMiDSIEQWRDKMNLEKMNLVGHSFG 240
Cdd:PRK00870  48 PVLLLHGEPSWSYLYRKMIPILAAAgHRVIAPDLIGFGRSDKPTRRED-YTYARHV-EWMRSWFEQLDLTDVTLVCQDWG 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17558492  241 GYLATSYALKYPKRVENLILAdpwgfNEMDPefaqklTSRQK--NIFWVIQQFN---P-LAVLRLVGGygpSLVRRLRPD 314
Cdd:PRK00870 126 GLIGLRLAAEHPDRFARLVVA-----NTGLP------TGDGPmpDAFWAWRAFSqysPvLPVGRLVNG---GTVRDLSDA 191

                        170
                 ....*....|....*....
gi 17558492  315 LALKYSEDVYDYIYLANSR 333
Cdd:PRK00870 192 VRAAYDAPFPDESYKAGAR 210
YbbA COG2819
Predicted hydrolase of the alpha/beta superfamily [General function prediction only];
234-285 1.15e-03

Predicted hydrolase of the alpha/beta superfamily [General function prediction only];


Pssm-ID: 442067 [Multi-domain]  Cd Length: 250  Bit Score: 40.35  E-value: 1.15e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 17558492 234 LVGHSFGGYLATSYALKYPKRVENLILADP---WGFNEMDPEFAQKLTSRQKNIF 285
Cdd:COG2819 134 LIGHSLGGLFSLYALLKYPDLFGRYIAISPslwWDDGALLDEAEALLKRSPLPKR 188
PRK05855 PRK05855
SDR family oxidoreductase;
163-208 4.56e-03

SDR family oxidoreductase;


Pssm-ID: 235628 [Multi-domain]  Cd Length: 582  Bit Score: 39.19  E-value: 4.56e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 17558492  163 IVLIHGFGAGVALWGSAIKRLA-QFQTVhAFDLPGFGRSSRPKFSSD 208
Cdd:PRK05855  28 VVLVHGYPDNHEVWDGVAPLLAdRFRVV-AYDVRGAGRSSAPKRTAA 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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