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Conserved domains on  [gi|283945598|ref|NP_084376|]
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partner of Y14 and mago isoform 1 [Mus musculus]

Protein Classification

mago-binding domain-containing protein( domain architecture ID 10558154)

mago-binding domain-containing protein similar to human partner of Y14 and mago (PYM), a key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Mago-bind pfam09282
Mago binding; Members of this family adopt a structure consisting of a small globular ...
 14-38 1.07e-07

Mago binding; Members of this family adopt a structure consisting of a small globular all-beta-domain, with a three-stranded beta-sheet and a contiguous beta-hairpin. They bind to Mago alpha-helices via extensive electrostatic interactions and at a beta2-beta3 loop via hydrophobic interactions.


:

Pssm-ID: 462741  Cd Length: 27  Bit Score: 46.28  E-value: 1.07e-07
                          10        20
                  ....*....|....*....|....*
gi 283945598   14 KYIASTQRPDGTWRKQRRVKEGYVP 38
Cdd:pfam09282   3 RIIPASRRPDGSVRKEIKVRPGYTP 27
 
Name Accession Description Interval E-value
Mago-bind pfam09282
Mago binding; Members of this family adopt a structure consisting of a small globular ...
 14-38 1.07e-07

Mago binding; Members of this family adopt a structure consisting of a small globular all-beta-domain, with a three-stranded beta-sheet and a contiguous beta-hairpin. They bind to Mago alpha-helices via extensive electrostatic interactions and at a beta2-beta3 loop via hydrophobic interactions.


Pssm-ID: 462741  Cd Length: 27  Bit Score: 46.28  E-value: 1.07e-07
                          10        20
                  ....*....|....*....|....*
gi 283945598   14 KYIASTQRPDGTWRKQRRVKEGYVP 38
Cdd:pfam09282   3 RIIPASRRPDGSVRKEIKVRPGYTP 27
 
Name Accession Description Interval E-value
Mago-bind pfam09282
Mago binding; Members of this family adopt a structure consisting of a small globular ...
 14-38 1.07e-07

Mago binding; Members of this family adopt a structure consisting of a small globular all-beta-domain, with a three-stranded beta-sheet and a contiguous beta-hairpin. They bind to Mago alpha-helices via extensive electrostatic interactions and at a beta2-beta3 loop via hydrophobic interactions.


Pssm-ID: 462741  Cd Length: 27  Bit Score: 46.28  E-value: 1.07e-07
                          10        20
                  ....*....|....*....|....*
gi 283945598   14 KYIASTQRPDGTWRKQRRVKEGYVP 38
Cdd:pfam09282   3 RIIPASRRPDGSVRKEIKVRPGYTP 27
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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