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Conserved domains on  [gi|58037455|ref|NP_083963|]
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WD repeat-containing protein 38 [Mus musculus]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 11455410)

WD40 repeat domain-containing protein similar to proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
PubMed:  10322433|8090199
SCOP:  4002744

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
18-300 1.32e-97

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 292.97  E-value: 1.32e-97
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  18 RVRFYGQHHGEVNCSAFSPDGRTLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWDV 97
Cdd:COG2319 112 LLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDL 191

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  98 ARSKCLHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVH 177
Cdd:COG2319 192 ATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVR 271

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 178 IWDLRASTPVvsyHNLEGHTGNISCLCYSASG-LLASGSWDKTICVWKPTTNNLPLQLKGHTIWVNSLAFSPDELKLASA 256
Cdd:COG2319 272 LWDLATGELL---RTLTGHSGGVNSVAFSPDGkLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASG 348

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....
gi 58037455 257 GYSRTVKVWDCLTGKCLETLKGMLDVAHACIFTPDGKLLVSGAA 300
Cdd:COG2319 349 SDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSA 392
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
18-300 1.32e-97

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 292.97  E-value: 1.32e-97
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  18 RVRFYGQHHGEVNCSAFSPDGRTLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWDV 97
Cdd:COG2319 112 LLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDL 191

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  98 ARSKCLHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVH 177
Cdd:COG2319 192 ATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVR 271

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 178 IWDLRASTPVvsyHNLEGHTGNISCLCYSASG-LLASGSWDKTICVWKPTTNNLPLQLKGHTIWVNSLAFSPDELKLASA 256
Cdd:COG2319 272 LWDLATGELL---RTLTGHSGGVNSVAFSPDGkLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASG 348

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....
gi 58037455 257 GYSRTVKVWDCLTGKCLETLKGMLDVAHACIFTPDGKLLVSGAA 300
Cdd:COG2319 349 SDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSA 392
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 25-300 1.35e-77

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 238.00  E-value: 1.35e-77
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  25 HHGEVNCSAFSPDGRTLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWDVARSKCLH 104
Cdd:cd00200   8 HTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVR 87

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 105 VLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWDLRAS 184
Cdd:cd00200  88 TLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTG 167

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 185 TPVvsyHNLEGHTGNISCLCYSASG-LLASGSWDKTICVWKPTTNNLPLQLKGHTIWVNSLAFSPDELKLASAGYSRTVK 263
Cdd:cd00200 168 KCV---ATLTGHTGEVNSVAFSPDGeKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIR 244

                       250       260       270
                ....*....|....*....|....*....|....*..
gi 58037455 264 VWDCLTGKCLETLKGMLDVAHACIFTPDGKLLVSGAA 300
Cdd:cd00200 245 VWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSA 281
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 83-265 6.33e-15

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 75.12  E-value: 6.33e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455   83 IASSSSDHSIRLWDVARSKCLHVLKGHQRSVETVSF-SPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFS 161
Cdd:PLN00181 548 VASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYsSADPTLLASGSDDGSVKLWSINQGVSIGTIKTKANICCVQFPS 627

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  162 PTSDSLATGSWDSTVHIWDLRasTPVVSYHNLEGHTGNISCLCYSASGLLASGSWDKTICVWKPTT-----NNLPLQ-LK 235
Cdd:PLN00181 628 ESGRSLAFGSADHKVYYYDLR--NPKLPLCTMIGHSKTVSYVRFVDSSTLVSSSTDNTLKLWDLSMsisgiNETPLHsFM 705

                        170       180       190
                 ....*....|....*....|....*....|
gi 58037455  236 GHTIWVNSLAFSPDELKLASAGYSRTVKVW 265
Cdd:PLN00181 706 GHTNVKNFVGLSVSDGYIATGSETNEVFVY 735
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 57-96 1.71e-09

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 52.31  E-value: 1.71e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 58037455     57 SGRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWD 96
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
58-96 1.76e-08

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 49.65  E-value: 1.76e-08
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 58037455    58 GRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWD 96
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
18-300 1.32e-97

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 292.97  E-value: 1.32e-97
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  18 RVRFYGQHHGEVNCSAFSPDGRTLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWDV 97
Cdd:COG2319 112 LLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDL 191

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  98 ARSKCLHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVH 177
Cdd:COG2319 192 ATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVR 271

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 178 IWDLRASTPVvsyHNLEGHTGNISCLCYSASG-LLASGSWDKTICVWKPTTNNLPLQLKGHTIWVNSLAFSPDELKLASA 256
Cdd:COG2319 272 LWDLATGELL---RTLTGHSGGVNSVAFSPDGkLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASG 348

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....
gi 58037455 257 GYSRTVKVWDCLTGKCLETLKGMLDVAHACIFTPDGKLLVSGAA 300
Cdd:COG2319 349 SDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSA 392
WD40 COG2319
WD40 repeat [General function prediction only];
7-300 1.14e-91

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 277.95  E-value: 1.14e-91
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455   7 NIRAPTRLAVGRVRFYGQHHGEVNCSAFSPDGRTLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGRLIASS 86
Cdd:COG2319  59 TLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASG 138

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  87 SSDHSIRLWDVARSKCLHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDS 166
Cdd:COG2319 139 SADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKL 218

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 167 LATGSWDSTVHIWDLRASTPVvsyHNLEGHTGNISCLCYSASG-LLASGSWDKTICVWKPTTNNLPLQLKGHTIWVNSLA 245
Cdd:COG2319 219 LASGSADGTVRLWDLATGKLL---RTLTGHSGSVRSVAFSPDGrLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVA 295

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*
gi 58037455 246 FSPDELKLASAGYSRTVKVWDCLTGKCLETLKGMLDVAHACIFTPDGKLLVSGAA 300
Cdd:COG2319 296 FSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSD 350
WD40 COG2319
WD40 repeat [General function prediction only];
25-266 9.14e-88

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 267.93  E-value: 9.14e-88
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  25 HHGEVNCSAFSPDGRTLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWDVARSKCLH 104
Cdd:COG2319 161 HSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLR 240

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 105 VLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWDLRAS 184
Cdd:COG2319 241 TLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATG 320

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 185 TPVvsyHNLEGHTGNISCLCYSASG-LLASGSWDKTICVWKPTTNNLPLQLKGHTIWVNSLAFSPDELKLASAGYSRTVK 263
Cdd:COG2319 321 KLL---RTLTGHTGAVRSVAFSPDGkTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVR 397


                ...
gi 58037455 264 VWD 266
Cdd:COG2319 398 LWD 400
WD40 COG2319
WD40 repeat [General function prediction only];
9-298 2.41e-79

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 246.36  E-value: 2.41e-79
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455   9 RAPTRLAVGRVRFYGQHHGEVNCSAFSPDGRTLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGRLIASSSS 88
Cdd:COG2319  19 ALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASA 98

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  89 DHSIRLWDVARSKCLHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLA 168
Cdd:COG2319  99 DGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLA 178

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 169 TGSWDSTVHIWDLRASTPVvsyHNLEGHTGNISCLCYSASG-LLASGSWDKTICVWKPTTNNLPLQLKGHTIWVNSLAFS 247
Cdd:COG2319 179 SGSDDGTVRLWDLATGKLL---RTLTGHTGAVRSVAFSPDGkLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFS 255

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|.
gi 58037455 248 PDELKLASAGYSRTVKVWDCLTGKCLETLKGMLDVAHACIFTPDGKLLVSG 298
Cdd:COG2319 256 PDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASG 306
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 25-300 1.35e-77

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 238.00  E-value: 1.35e-77
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  25 HHGEVNCSAFSPDGRTLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWDVARSKCLH 104
Cdd:cd00200   8 HTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVR 87

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 105 VLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWDLRAS 184
Cdd:cd00200  88 TLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTG 167

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 185 TPVvsyHNLEGHTGNISCLCYSASG-LLASGSWDKTICVWKPTTNNLPLQLKGHTIWVNSLAFSPDELKLASAGYSRTVK 263
Cdd:cd00200 168 KCV---ATLTGHTGEVNSVAFSPDGeKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIR 244

                       250       260       270
                ....*....|....*....|....*....|....*..
gi 58037455 264 VWDCLTGKCLETLKGMLDVAHACIFTPDGKLLVSGAA 300
Cdd:cd00200 245 VWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSA 281
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 25-266 7.03e-71

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 221.05  E-value: 7.03e-71
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  25 HHGEVNCSAFSPDGRTLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWDVARSKCLH 104
Cdd:cd00200  50 HTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLT 129

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 105 VLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWDLRAS 184
Cdd:cd00200 130 TLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTG 209

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 185 TPVvsyHNLEGHTGNISCLCYSASG-LLASGSWDKTICVWKPTTNNLPLQLKGHTIWVNSLAFSPDELKLASAGYSRTVK 263
Cdd:cd00200 210 KCL---GTLRGHENGVNSVAFSPDGyLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIR 286


                ...
gi 58037455 264 VWD 266
Cdd:cd00200 287 IWD 289
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 64-300 6.22e-69

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 216.05  E-value: 6.22e-69
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  64 LAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWDVARSKCLHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGR 143
Cdd:cd00200   5 LKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGE 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 144 RVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWDLRASTPVvsyHNLEGHTGNISCLCYS-ASGLLASGSWDKTICV 222
Cdd:cd00200  85 CVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCL---TTLRGHTDWVNSVAFSpDGTFVASSSQDGTIKL 161

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 58037455 223 WKPTTNNLPLQLKGHTIWVNSLAFSPDELKLASAGYSRTVKVWDCLTGKCLETLKGMLDVAHACIFTPDGKLLVSGAA 300
Cdd:cd00200 162 WDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSE 239
WD40 COG2319
WD40 repeat [General function prediction only];
25-227 7.28e-69

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 219.40  E-value: 7.28e-69
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  25 HHGEVNCSAFSPDGRTLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWDVARSKCLH 104
Cdd:COG2319 203 HTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLR 282

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 105 VLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWDLRAS 184
Cdd:COG2319 283 TLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATG 362

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....
gi 58037455 185 TPVvsyHNLEGHTGNISCLCYSASG-LLASGSWDKTICVWKPTT 227
Cdd:COG2319 363 ELL---RTLTGHTGAVTSVAFSPDGrTLASGSADGTVRLWDLAT 403
WD40 COG2319
WD40 repeat [General function prediction only];
33-298 2.74e-65

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 210.15  E-value: 2.74e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  33 AFSPDGRTLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWDVARSKCLHVLKGHQRS 112
Cdd:COG2319   1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 113 VETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWDLRASTPVvsyHN 192
Cdd:COG2319  81 VLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLL---RT 157

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 193 LEGHTGNISCLCYSASG-LLASGSWDKTICVWKPTTNNLPLQLKGHTIWVNSLAFSPDELKLASAGYSRTVKVWDCLTGK 271
Cdd:COG2319 158 LTGHSGAVTSVAFSPDGkLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGK 237

                       250       260
                ....*....|....*....|....*..
gi 58037455 272 CLETLKGMLDVAHACIFTPDGKLLVSG 298
Cdd:COG2319 238 LLRTLTGHSGSVRSVAFSPDGRLLASG 264
WD40 COG2319
WD40 repeat [General function prediction only];
19-182 2.62e-57

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 189.35  E-value: 2.62e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  19 VRFYGQHHGEVNCSAFSPDGRTLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWDVA 98
Cdd:COG2319 239 LRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLA 318

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  99 RSKCLHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHI 178
Cdd:COG2319 319 TGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRL 398


                ....
gi 58037455 179 WDLR 182
Cdd:COG2319 399 WDLA 402
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 19-224 6.76e-57

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 184.85  E-value: 6.76e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  19 VRFYGQHHGEVNCSAFSPDGRTLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWDVA 98
Cdd:cd00200  86 VRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLR 165

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  99 RSKCLHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHI 178
Cdd:cd00200 166 TGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIRV 245

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*..
gi 58037455 179 WDLRASTPVvsyHNLEGHTGNISCLCYSASG-LLASGSWDKTICVWK 224
Cdd:cd00200 246 WDLRTGECV---QTLSGHTNSVTSLAWSPDGkRLASGSADGTIRIWD 289
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 102-300 1.37e-48

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 163.66  E-value: 1.37e-48
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 102 CLHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWDL 181
Cdd:cd00200   1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 182 RASTPVvsyHNLEGHTGNISCLCYSASG-LLASGSWDKTICVWKPTTNNLPLQLKGHTIWVNSLAFSPDELKLASAGYSR 260
Cdd:cd00200  81 ETGECV---RTLTGHTSYVSSVAFSPDGrILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDG 157

                       170       180       190       200
                ....*....|....*....|....*....|....*....|
gi 58037455 261 TVKVWDCLTGKCLETLKGMLDVAHACIFTPDGKLLVSGAA 300
Cdd:cd00200 158 TIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSS 197
WD40 COG2319
WD40 repeat [General function prediction only];
18-141 1.51e-40

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 145.44  E-value: 1.51e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  18 RVRFYGQHHGEVNCSAFSPDGRTLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWDV 97
Cdd:COG2319 280 LLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDL 359

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 58037455  98 ARSKCLHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWEVQS 141
Cdd:COG2319 360 ATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
WD40 COG2319
WD40 repeat [General function prediction only];
159-300 1.45e-16

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 79.18  E-value: 1.45e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455 159 DFSPTSDSLATGSWDSTVHIWDLRasTPVVSYHNLEGHTGNISCLCYSASGLLASGSWDKTICVWKPTTNNLPLQLKGHT 238
Cdd:COG2319   1 ALSADGAALAAASADLALALLAAA--LGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHT 78

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 58037455 239 IWVNSLAFSPDELKLASAGYSRTVKVWDCLTGKCLETLKGMLDVAHACIFTPDGKLLVSGAA 300
Cdd:COG2319  79 AAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSA 140
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 83-265 6.33e-15

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 75.12  E-value: 6.33e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455   83 IASSSSDHSIRLWDVARSKCLHVLKGHQRSVETVSF-SPDSKQLASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFS 161
Cdd:PLN00181 548 VASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYsSADPTLLASGSDDGSVKLWSINQGVSIGTIKTKANICCVQFPS 627

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  162 PTSDSLATGSWDSTVHIWDLRasTPVVSYHNLEGHTGNISCLCYSASGLLASGSWDKTICVWKPTT-----NNLPLQ-LK 235
Cdd:PLN00181 628 ESGRSLAFGSADHKVYYYDLR--NPKLPLCTMIGHSKTVSYVRFVDSSTLVSSSTDNTLKLWDLSMsisgiNETPLHsFM 705

                        170       180       190
                 ....*....|....*....|....*....|
gi 58037455  236 GHTIWVNSLAFSPDELKLASAGYSRTVKVW 265
Cdd:PLN00181 706 GHTNVKNFVGLSVSDGYIATGSETNEVFVY 735
PTZ00421 PTZ00421
coronin; Provisional
 24-204 1.65e-11

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 64.53  E-value: 1.65e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455   24 QHHGEVNCSAFSPDGRTLLTASDDGCVYVWGTKSGRLLWR-------------LAGHRGPVKSCCFSP-DGRLIASSSSD 89
Cdd:PTZ00421  18 RHFLNVTPSTALWDCSNTIACNDRFIAVPWQQLGSTAVLKhtdygklasnppiLLGQEGPIIDVAFNPfDPQKLFTASED 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455   90 HSIRLWDVAR-------SKCLHVLKGHQRSVETVSFSPDSKQ-LASGGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFS 161
Cdd:PTZ00421  98 GTIMGWGIPEegltqniSDPIVHLQGHTKKVGIVSFHPSAMNvLASAGADMVVNVWDVERGKAVEVIKCHSDQITSLEWN 177

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 58037455  162 PTSDSLATGSWDSTVHIWDLRASTPVVSyhnLEGHTGNISCLC 204
Cdd:PTZ00421 178 LDGSLLCTTSKDKKLNIIDPRDGTIVSS---VEAHASAKSQRC 217
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 47-223 8.62e-11

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 62.41  E-value: 8.62e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455   47 DGCVYVWGTKSGRLLWRLAGHRGPVKSCCFSP-DGRLIASSSSDHSIRLWDVARSKCLHVLKGhQRSVETVSFSPDS-KQ 124
Cdd:PLN00181 554 EGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSaDPTLLASGSDDGSVKLWSINQGVSIGTIKT-KANICCVQFPSESgRS 632

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  125 LASGGWDKRAIVWEVQSGR-RVHLLVGHCDSIQSSDFSPTSdSLATGSWDSTVHIWDLRASTPVVS---YHNLEGHTGNI 200
Cdd:PLN00181 633 LAFGSADHKVYYYDLRNPKlPLCTMIGHSKTVSYVRFVDSS-TLVSSSTDNTLKLWDLSMSISGINetpLHSFMGHTNVK 711

                        170       180
                 ....*....|....*....|....
gi 58037455  201 SCLCYSAS-GLLASGSWDKTICVW 223
Cdd:PLN00181 712 NFVGLSVSdGYIATGSETNEVFVY 735
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 35-215 1.85e-10

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 61.64  E-value: 1.85e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455   35 SPDGRTLLTASDDGCVYVWGTKSGRLLwrlaghrGPVKS----CCF---SPDGRLIASSSSDHSIRLWDVARSKC-LHVL 106
Cdd:PLN00181 585 SADPTLLASGSDDGSVKLWSINQGVSI-------GTIKTkaniCCVqfpSESGRSLAFGSADHKVYYYDLRNPKLpLCTM 657

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  107 KGHQRSVETVSFSpDSKQLASGGWDKRAIVWEVQ---SG---RRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWD 180
Cdd:PLN00181 658 IGHSKTVSYVRFV-DSSTLVSSSTDNTLKLWDLSmsiSGineTPLHSFMGHTNVKNFVGLSVSDGYIATGSETNEVFVYH 736

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 58037455  181 LRASTPVVSY--HNLEGHTG--------NISCLCY--SASGLLASGS 215
Cdd:PLN00181 737 KAFPMPVLSYkfKTIDPVSGlevddasqFISSVCWrgQSSTLVAANS 783
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 33-163 1.05e-09

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 59.28  E-value: 1.05e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455   33 AFSPDGRTLLTASD-DGCVYVW-----GTKSGRllwRLA----GHR-GPVksccFSPDGRLIASSSSDHSIRLWDVARSK 101
Cdd:COG4946  349 AWSPDGKSIAYFSDaSGEYELYiapadGSGEPK---QLTlgdlGRVfNPV----WSPDGKKIAFTDNRGRLWVVDLASGK 421

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 58037455  102 CLHVLKG-HQRSVETVSFSPDSKQLA---SGGWDKRAI-VWEVQSGRRVHLLVGhcdsiQSSDFSPT 163
Cdd:COG4946  422 VRKVDTDgYGDGISDLAWSPDSKWLAyskPGPNQLSQIfLYDVETGKTVQLTDG-----RYDDGSPA 483
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 57-96 1.71e-09

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 52.31  E-value: 1.71e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 58037455     57 SGRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWD 96
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
58-96 1.76e-08

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 49.65  E-value: 1.76e-08
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 58037455    58 GRLLWRLAGHRGPVKSCCFSPDGRLIASSSSDHSIRLWD 96
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 76-266 5.54e-08

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 53.94  E-value: 5.54e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455   76 FSPDGRLIASSSSDHSIRLWDvarskCLHVLKG----HQRSVETVSFSPDS---------KQLASGGWDKRAIVWEVQSG 142
Cdd:PLN00181 491 FDRDGEFFATAGVNKKIKIFE-----CESIIKDgrdiHYPVVELASRSKLSgicwnsyikSQVASSNFEGVVQVWDVARS 565

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  143 RRVHLLVGHCDSIQSSDFSPTSDS-LATGSWDSTVHIWDLRASTPVVSYHNleghTGNISCLCY-SASGL-LASGSWDKT 219
Cdd:PLN00181 566 QLVTEMKEHEKRVWSIDYSSADPTlLASGSDDGSVKLWSINQGVSIGTIKT----KANICCVQFpSESGRsLAFGSADHK 641

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 58037455  220 ICVWKPTTNNLPL-QLKGHTIWVNSLAFSpDELKLASAGYSRTVKVWD 266
Cdd:PLN00181 642 VYYYDLRNPKLPLcTMIGHSKTVSYVRFV-DSSTLVSSSTDNTLKLWD 688
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 101-138 4.06e-07

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 45.77  E-value: 4.06e-07
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 58037455    101 KCLHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWE 138
Cdd:smart00320   3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 227-266 1.16e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 44.61  E-value: 1.16e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 58037455    227 TNNLPLQLKGHTIWVNSLAFSPDELKLASAGYSRTVKVWD 266
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
100-138 1.29e-06

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 44.26  E-value: 1.29e-06
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 58037455   100 SKCLHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVWE 138
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
33-142 2.19e-06

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 47.77  E-value: 2.19e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  33 AFSPDGRTLL-TASDDGCVYVWGTKSGRLLWRLAGHRGPVkSCCFSPDG-RLIASSSSDHSI----RLWDVARSKCLHVL 106
Cdd:COG3391 116 AVDPDGGRLYvADSGNGRVSVIDTATGKVVATIPVGAGPH-GIAVDPDGkRLYVANSGSNTVsvivSVIDTATGKVVATI 194

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 58037455 107 KGHQRSVeTVSFSPDSKQL--------ASGGWDKRAIVWEVQSG 142
Cdd:COG3391 195 PVGGGPV-GVAVSPDGRRLyvanrgsnTSNGGSNTVSVIDLATL 237
PTZ00420 PTZ00420
coronin; Provisional
 91-266 2.98e-06

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 48.41  E-value: 2.98e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455   91 SIRLWDVARSKCLHVLKGHQRSVETVSFSP-DSKQLASGGWDKRAIVWEV----QSGRRVH----LLVGHCDSIQSSDFS 161
Cdd:PTZ00420  55 AIRLENQMRKPPVIKLKGHTSSILDLQFNPcFSEILASGSEDLTIRVWEIphndESVKEIKdpqcILKGHKKKISIIDWN 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  162 PTSDS-LATGSWDSTVHIWDL----RASTPVVSyhnleghtGNISCLCYSASGLLASGSW-DKTICVWKPTTNNLPLQLK 235
Cdd:PTZ00420 135 PMNYYiMCSSGFDSFVNIWDIenekRAFQINMP--------KKLSSLKWNIKGNLLSGTCvGKHMHIIDPRKQEIASSFH 206

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 58037455  236 GHT-------IWVNslAFSPDELKLASAGYS----RTVKVWD 266
Cdd:PTZ00420 207 IHDggkntknIWID--GLGGDDNYILSTGFSknnmREMKLWD 246
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 141-180 3.02e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 43.46  E-value: 3.02e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 58037455    141 SGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWD 180
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 33-126 3.97e-06

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 45.82  E-value: 3.97e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  33 AFSPDGRTLLTASDDGC---VYVW---GTKSGRLLWRLAGHRGPVksccFSPDGRLIA-SSSSDHSIRLW--DVARSKCL 103
Cdd:COG0823  37 AWSPDGRRIAFTSDRGGgpqIYVVdadGGEPRRLTFGGGYNASPS----WSPDGKRLAfVSRSDGRFDIYvlDLDGGAPR 112

                        90       100
                ....*....|....*....|...
gi 58037455 104 HVLKGHQrsveTVSFSPDSKQLA 126
Cdd:COG0823 113 RLTDGPG----SPSWSPDGRRIV 131
PTZ00421 PTZ00421
coronin; Provisional
 211-297 4.29e-06

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 47.97  E-value: 4.29e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  211 LASGSWDKTICVWKPTTNNLP-------LQLKGHTIWVNSLAFSPDELK-LASAGYSRTVKVWDCLTGKCLETLKGMLDV 282
Cdd:PTZ00421  91 LFTASEDGTIMGWGIPEEGLTqnisdpiVHLQGHTKKVGIVSFHPSAMNvLASAGADMVVNVWDVERGKAVEVIKCHSDQ 170

                         90
                 ....*....|....*
gi 58037455  283 AHACIFTPDGKLLVS 297
Cdd:PTZ00421 171 ITSLEWNLDGSLLCT 185
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 19-53 5.77e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 42.68  E-value: 5.77e-06
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 58037455     19 VRFYGQHHGEVNCSAFSPDGRTLLTASDDGCVYVW 53
Cdd:smart00320   5 LKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLW 39
WD40 pfam00400
WD domain, G-beta repeat;
234-266 7.88e-06

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 41.95  E-value: 7.88e-06
                          10        20        30
                  ....*....|....*....|....*....|...
gi 58037455   234 LKGHTIWVNSLAFSPDELKLASAGYSRTVKVWD 266
Cdd:pfam00400   7 LEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 pfam00400
WD domain, G-beta repeat;
142-180 1.06e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 41.56  E-value: 1.06e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 58037455   142 GRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWD 180
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 191-224 1.14e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 41.53  E-value: 1.14e-05
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 58037455    191 HNLEGHTGNISCLCYSASG-LLASGSWDKTICVWK 224
Cdd:smart00320   6 KTLKGHTGPVTSVAFSPDGkYLASGSDDGTIKLWD 40
PTZ00420 PTZ00420
coronin; Provisional
 63-230 1.29e-05

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 46.48  E-value: 1.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455   63 RLAGHRGPVKSCCFSP-DGRLIASSSSDHSIRLWDVARS----------KClhVLKGHQRSVETVSFSP-DSKQLASGGW 130
Cdd:PTZ00420  69 KLKGHTSSILDLQFNPcFSEILASGSEDLTIRVWEIPHNdesvkeikdpQC--ILKGHKKKISIIDWNPmNYYIMCSSGF 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  131 DKRAIVWEVQSGRRVHLLVgHCDSIQSSDFSPTSDSLATGSWDSTVHIWDLRASTPVVSYHNlegHTGNISCLCYSASGL 210
Cdd:PTZ00420 147 DSFVNIWDIENEKRAFQIN-MPKKLSSLKWNIKGNLLSGTCVGKHMHIIDPRKQEIASSFHI---HDGGKNTKNIWIDGL 222

                        170       180
                 ....*....|....*....|
gi 58037455  211 lasGSWDKTICVWKPTTNNL 230
Cdd:PTZ00420 223 ---GGDDNYILSTGFSKNNM 239
ANAPC4_WD40 pfam12894
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ...
 44-119 1.89e-05

Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,


Pssm-ID: 403945 [Multi-domain]  Cd Length: 91  Bit Score: 42.65  E-value: 1.89e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 58037455    44 ASDDGCVYVWGTkSGRLLWRLAG--HRGPVKSCCFSPDGRLIASSSSDHSIRLWDVARSKCLHVLKGHQRSVETVSFS 119
Cdd:pfam12894  13 ATEDGELLLHRL-NWQRVWTLSPdkEDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKIVHHFSAGSDLITCLGWG 89
WD40 pfam00400
WD domain, G-beta repeat;
191-223 1.97e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 41.18  E-value: 1.97e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 58037455   191 HNLEGHTGNISCLCYSASG-LLASGSWDKTICVW 223
Cdd:pfam00400   5 KTLEGHTGSVTSLAFSPDGkLLASGSDDGTVKVW 38
Ge1_WD40 pfam16529
WD40 region of Ge1, enhancer of mRNA-decapping protein; Ge1_WD40 is the N-terminal region of ...
 24-121 2.51e-05

WD40 region of Ge1, enhancer of mRNA-decapping protein; Ge1_WD40 is the N-terminal region of Ge-1 or enhancer of mRNA-decapping proteins. WD40-repeat regions are involved in protein-protein interactions.


Pssm-ID: 465162 [Multi-domain]  Cd Length: 328  Bit Score: 45.14  E-value: 2.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455    24 QHHGEVNCSAFSPDGRTLLTASDDGCV-----YVWGTKSGRLLWRLAGHRGPVKSCCF-------SPDGR----LIASSS 87
Cdd:pfam16529 184 EEHSLLVDAAFSPDGTALATASLDGEVkffqiYLFDNRNPRCLHEWKPHDGKPLSSLFfldnhkkPPEVQfwrfAITGAD 263

                          90       100       110
                  ....*....|....*....|....*....|....
gi 58037455    88 SDHSIRLWDVARSKCLhvlkghqrsvETVSFSPD 121
Cdd:pfam16529 264 NNSELKLWSCESWTCL----------QTIRFVPD 287
WD40 pfam00400
WD domain, G-beta repeat;
19-53 4.07e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 40.02  E-value: 4.07e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 58037455    19 VRFYGQHHGEVNCSAFSPDGRTLLTASDDGCVYVW 53
Cdd:pfam00400   4 LKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
WD40 COG2319
WD40 repeat [General function prediction only];
17-53 4.27e-05

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 44.52  E-value: 4.27e-05
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 58037455  17 GRVRFYGQHHGEVNCSAFSPDGRTLLTASDDGCVYVW 53
Cdd:COG2319 363 ELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLW 399
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 29-137 4.59e-05

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 45.08  E-value: 4.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455   29 VNCSAFSPD-GRTLLTASDDGCVYVWGTKSGRL-LWRLAGHRGPVKSCCFSpDGRLIASSSSDHSIRLWDVARSKC---- 102
Cdd:PLN00181 620 ICCVQFPSEsGRSLAFGSADHKVYYYDLRNPKLpLCTMIGHSKTVSYVRFV-DSSTLVSSSTDNTLKLWDLSMSISgine 698

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 58037455  103 --LHVLKGHQRSVETVSFSPDSKQLASGGWDKRAIVW 137
Cdd:PLN00181 699 tpLHSFMGHTNVKNFVGLSVSDGYIATGSETNEVFVY 735
NBCH_WD40 pfam20426
Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at ...
 128-222 1.72e-04

Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at the C-terminus of neurobeachin-like proteins.


Pssm-ID: 466575 [Multi-domain]  Cd Length: 350  Bit Score: 42.75  E-value: 1.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455   128 GGWDKRAIVWEVQSGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWD-LRASTP----------------VVS- 189
Cdd:pfam20426 100 GNWENSFQVISLNDGRMVQSIRQHKDVVSCVAVTSDGSILATGSYDTTVMVWEvLRGRSSekrsrntqtefprkdhVIAe 179

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 58037455   190 --YHNLEGHTGNISCLCYSAS-GLLASGSWDKTiCV 222
Cdd:pfam20426 180 tpFHILCGHDDIITCLYVSVElDIVISGSKDGT-CI 214
PTZ00421 PTZ00421
coronin; Provisional
 147-266 7.49e-04

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 41.03  E-value: 7.49e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  147 LLVGHCDSIQSSDFSPTSDS-LATGSWDSTVHIWDLRA-------STPVVsyhNLEGHTGNISCLCY--SASGLLASGSW 216
Cdd:PTZ00421  70 ILLGQEGPIIDVAFNPFDPQkLFTASEDGTIMGWGIPEegltqniSDPIV---HLQGHTKKVGIVSFhpSAMNVLASAGA 146

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 58037455  217 DKTICVWKPTTNNLPLQLKGHTIWVNSLAFSPDELKLASAGYSRTVKVWD 266
Cdd:PTZ00421 147 DMVVNVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIID 196
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 50-168 1.07e-03

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 38.88  E-value: 1.07e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  50 VYVWGTKSGRLlWRLAGHRGPVKSCCFSPDGRLIA-SSSSDHSIRLW--DVARSKcLHVLKGHQRSVETVSFSPDSKQLA 126
Cdd:COG0823  13 IYVVDLDGGEP-RRLTNSPGIDTSPAWSPDGRRIAfTSDRGGGPQIYvvDADGGE-PRRLTFGGGYNASPSWSPDGKRLA 90

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*..
gi 58037455 127 -----SGGWDkraIVWEVQSGRRVHLLVghcDSIQSSDFSPTSDSLA 168
Cdd:COG0823  91 fvsrsDGRFD---IYVLDLDGGAPRRLT---DGPGSPSWSPDGRRIV 131
PTZ00420 PTZ00420
coronin; Provisional
 134-223 1.40e-03

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 39.93  E-value: 1.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  134 AIVWEVQSG------------RR--VHLLVGHCDSIQSSDFSPT-SDSLATGSWDSTVHIWDLRASTPVVSYHN-----L 193
Cdd:PTZ00420  42 AVPWEVEGGgligairlenqmRKppVIKLKGHTSSILDLQFNPCfSEILASGSEDLTIRVWEIPHNDESVKEIKdpqciL 121

                         90       100       110
                 ....*....|....*....|....*....|..
gi 58037455  194 EGHTGNISCLCYSASG--LLASGSWDKTICVW 223
Cdd:PTZ00420 122 KGHKKKISIIDWNPMNyyIMCSSGFDSFVNIW 153
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 17-125 1.86e-03

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 39.10  E-value: 1.86e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455  17 GRVRFYGQHHGEVNCSAFSPDGRtLLTASDDGCVYVWGTKSGRLLWRLAGHRGPVKSC---CFSPDGRLIASSSSDHSI- 92
Cdd:COG3386  39 GAVEVFAEPSGRPNGLAFDPDGR-LLVADHGRGLVRFDPADGEVTVLADEYGKPLNRPndgVVDPDGRLYFTDMGEYLPt 117

                        90       100       110
                ....*....|....*....|....*....|....
gi 58037455  93 -RLWDVARSKCLHVLKGHQRSVETVSFSPDSKQL 125
Cdd:COG3386 118 gALYRVDPDGSLRVLADGLTFPNGIAFSPDGRTL 151
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 33-97 7.40e-03

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 36.57  E-value: 7.40e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 58037455  33 AFSPDGRTLLTASDDG-----CVYVWGTKSGRLLWRlaGHRGPVksccFSPDGRLIA-SSSSDHSIRLWDV 97
Cdd:COG0823  81 SWSPDGKRLAFVSRSDgrfdiYVLDLDGGAPRRLTD--GPGSPS----WSPDGRRIVfSSDRGGRPDLYVV 145
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 25-126 7.44e-03

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 38.10  E-value: 7.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58037455   25 HHGEVNCSAFSPDGRTL-LTASDDGC--VYVWGTKSG---RLLWrlagHRGPVKSCCFSPDGRLIASSSSDHSI-----R 93
Cdd:COG4946   59 HPGYESFPRFSPDGKWIaFTSDYDGNtdVYVMPAEGGepkRLTY----HPANDRVVGWTPDGKSVLFASNRGSPpsrsnQ 134

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 58037455   94 LWDVArskclhvLKGHQR------SVETVSFSPDSKQLA 126
Cdd:COG4946  135 LYTVP-------VDGGLPerlplpPAGDGSFSPDGKKLA 166
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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