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solute carrier family 12 member 3 isoform 2 [Mus musculus]
Protein Classification
solute carrier family 12 protein ( domain architecture ID 11489985 )
solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis, or human kidney-specific Na-K-Cl symporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation
List of domain hits
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
57-1000
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1572.41
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 57 NT I D V VP AY EHY A NS ALP G E P RKV RP T L AD LH SF L - K EG S H L HA LA FDGRQ G RELTDGLVEDETGTNS EK S P GEP V R FGW 135
Cdd:TIGR00930 1 NT V D A VP RI EHY R NS EGQ G G P KRN RP S L EE LH DL L d K VV S L L GP LA DYTNN G QGMKEHEEAEDAEGTK EK P P AGA V K FGW 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 136 V K GV MIR C M LNIWGVIL Y LRL P WI TA QAGI V L TW LIILL SVM VT S ITGLS I SAI S TNG K VK S GG T Y F LISRSLGPE L GGS 215
Cdd:TIGR00930 81 V M GV LVP C L LNIWGVIL F LRL S WI VG QAGI G L SL LIILL CCC VT T ITGLS M SAI A TNG V VK G GG A Y Y LISRSLGPE F GGS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 216 IGLIFAFANAV G VAM HT VGFAETV R DLL Q E Y G TP I - VDPINDIRI I G V VTV T VLL A IS L AGMEWE S KAQVLF FLVIMV S F 294
Cdd:TIGR00930 161 IGLIFAFANAV A VAM YV VGFAETV L DLL R E N G SK I m VDPINDIRI Y G T VTV V VLL G IS F AGMEWE N KAQVLF LVIVLL S I 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 295 A N YL VGT L IPA S e DK AS KGF YSYHGD IF VQ N LV P DWR G ID G S FF GM F S IFFPS A TGILAGANISGDLKDP AV AIPKGTL M 374
Cdd:TIGR00930 241 L N IF VGT I IPA F - DK PA KGF FGLGNE IF SE N FI P GIP G PE G G FF SL F G IFFPS V TGILAGANISGDLKDP QK AIPKGTL L 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 375 AI FW TT IS YL AISATI G S CVVRDA S GD V NDT MTPG pgp C EGL AC gygwn F T EC SQQ r S C R YGL I N YY Q T MS M VS A F A PLI 454
Cdd:TIGR00930 320 AI LT TT VV YL GSVVLF G A CVVRDA T GD K NDT LVTN --- C TSA AC ----- F S EC AHN - T C S YGL M N NL Q V MS L VS P F P PLI 390
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 455 TAGIF G ATLSSALA C LVSA AKV FQ C LC E D QL YP LIG FFGKGYGKN R EP V R G YLL AYA IA VA FI I IAELNTIAPIISNFFL 534
Cdd:TIGR00930 391 TAGIF S ATLSSALA S LVSA PRL FQ A LC K D NI YP FLQ FFGKGYGKN G EP L R A YLL TAF IA EG FI L IAELNTIAPIISNFFL 470
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 535 C SYALINFSCFHAS ITN SPGWRP S F R YY SK W AA L F GA VISVV IMFL LT WWAAL I A IGVV LFL LL YV I YKKP E VNWGSS V Q 614
Cdd:TIGR00930 471 A SYALINFSCFHAS LLR SPGWRP R F K YY HW W LS L L GA SLCCA IMFL IS WWAAL V A MVIA LFL YK YV T YKKP D VNWGSS T Q 550
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 615 A G SY N LAL SYSVG L N EVEDH I KN Y RPQCLVLTGPP NF RPAL V DF V S T FT QNLS LMICG H V LI GP GKQR V P E LRLIASGHT 694
Cdd:TIGR00930 551 A L SY S LAL YSLLR L E EVEDH V KN W RPQCLVLTGPP VC RPAL L DF A S Q FT KGKG LMICG S V IQ GP RLEC V K E AQAAEAKIQ 630
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 695 K WL N K R K I KAFY SD V I A E DLR S GV QI L M QASGLGRMKPN I LV V G F K RN W QS A H P ATV E D YIG VL HDAFD FNYG V C V M R MR 774
Cdd:TIGR00930 631 T WL E K N K V KAFY AV V V A D DLR E GV RH L I QASGLGRMKPN T LV M G Y K KD W RQ A E P RAW E T YIG II HDAFD AHLA V V V V R NS 710
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 775 EGL NV S e A LQ TH ----------------- TTPEALIQEEQ AST I FQ SE QGK K TID IY WL F DDGGLTLL I PYLL HR KK R W G 837
Cdd:TIGR00930 711 EGL PI S - V LQ VQ eelendcsedsielndg KISTQPDMHLE AST Q FQ KK QGK G TID VW WL V DDGGLTLL L PYLL TT KK V W K 789
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 838 KCKIR V FVG G Q - IN R MDE E R K AIIS LL S KFR LGFHEVH VL P DIN Q KPQ A E HTKR FE D MI A PFRL NDGF KD EATVT - E M RR 915
Cdd:TIGR00930 790 KCKIR I FVG A Q k DD R SEQ E K K DMAT LL Y KFR IDAEVIV VL M DIN A KPQ T E SMEA FE E MI R PFRL HKTE KD REAKD p K M TW 869
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 916 DC PWKI S D E E INK N RI KS L RQVRL S E I LL D YSRDAAL II L T LP IG RKG KC P SS LYMAWLE T LS Q DL r PPVLL I RGN QE NV 995
Cdd:TIGR00930 870 TK PWKI T D A E LQS N VR KS Y RQVRL N E L LL E YSRDAAL VV L S LP VP RKG SI P DE LYMAWLE V LS E DL - PPVLL V RGN HR NV 948
....*
gi 247301365 996 LTFY C 1000
Cdd:TIGR00930 949 LTFY S 953
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
57-1000
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1572.41
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 57 NT I D V VP AY EHY A NS ALP G E P RKV RP T L AD LH SF L - K EG S H L HA LA FDGRQ G RELTDGLVEDETGTNS EK S P GEP V R FGW 135
Cdd:TIGR00930 1 NT V D A VP RI EHY R NS EGQ G G P KRN RP S L EE LH DL L d K VV S L L GP LA DYTNN G QGMKEHEEAEDAEGTK EK P P AGA V K FGW 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 136 V K GV MIR C M LNIWGVIL Y LRL P WI TA QAGI V L TW LIILL SVM VT S ITGLS I SAI S TNG K VK S GG T Y F LISRSLGPE L GGS 215
Cdd:TIGR00930 81 V M GV LVP C L LNIWGVIL F LRL S WI VG QAGI G L SL LIILL CCC VT T ITGLS M SAI A TNG V VK G GG A Y Y LISRSLGPE F GGS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 216 IGLIFAFANAV G VAM HT VGFAETV R DLL Q E Y G TP I - VDPINDIRI I G V VTV T VLL A IS L AGMEWE S KAQVLF FLVIMV S F 294
Cdd:TIGR00930 161 IGLIFAFANAV A VAM YV VGFAETV L DLL R E N G SK I m VDPINDIRI Y G T VTV V VLL G IS F AGMEWE N KAQVLF LVIVLL S I 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 295 A N YL VGT L IPA S e DK AS KGF YSYHGD IF VQ N LV P DWR G ID G S FF GM F S IFFPS A TGILAGANISGDLKDP AV AIPKGTL M 374
Cdd:TIGR00930 241 L N IF VGT I IPA F - DK PA KGF FGLGNE IF SE N FI P GIP G PE G G FF SL F G IFFPS V TGILAGANISGDLKDP QK AIPKGTL L 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 375 AI FW TT IS YL AISATI G S CVVRDA S GD V NDT MTPG pgp C EGL AC gygwn F T EC SQQ r S C R YGL I N YY Q T MS M VS A F A PLI 454
Cdd:TIGR00930 320 AI LT TT VV YL GSVVLF G A CVVRDA T GD K NDT LVTN --- C TSA AC ----- F S EC AHN - T C S YGL M N NL Q V MS L VS P F P PLI 390
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 455 TAGIF G ATLSSALA C LVSA AKV FQ C LC E D QL YP LIG FFGKGYGKN R EP V R G YLL AYA IA VA FI I IAELNTIAPIISNFFL 534
Cdd:TIGR00930 391 TAGIF S ATLSSALA S LVSA PRL FQ A LC K D NI YP FLQ FFGKGYGKN G EP L R A YLL TAF IA EG FI L IAELNTIAPIISNFFL 470
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 535 C SYALINFSCFHAS ITN SPGWRP S F R YY SK W AA L F GA VISVV IMFL LT WWAAL I A IGVV LFL LL YV I YKKP E VNWGSS V Q 614
Cdd:TIGR00930 471 A SYALINFSCFHAS LLR SPGWRP R F K YY HW W LS L L GA SLCCA IMFL IS WWAAL V A MVIA LFL YK YV T YKKP D VNWGSS T Q 550
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 615 A G SY N LAL SYSVG L N EVEDH I KN Y RPQCLVLTGPP NF RPAL V DF V S T FT QNLS LMICG H V LI GP GKQR V P E LRLIASGHT 694
Cdd:TIGR00930 551 A L SY S LAL YSLLR L E EVEDH V KN W RPQCLVLTGPP VC RPAL L DF A S Q FT KGKG LMICG S V IQ GP RLEC V K E AQAAEAKIQ 630
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 695 K WL N K R K I KAFY SD V I A E DLR S GV QI L M QASGLGRMKPN I LV V G F K RN W QS A H P ATV E D YIG VL HDAFD FNYG V C V M R MR 774
Cdd:TIGR00930 631 T WL E K N K V KAFY AV V V A D DLR E GV RH L I QASGLGRMKPN T LV M G Y K KD W RQ A E P RAW E T YIG II HDAFD AHLA V V V V R NS 710
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 775 EGL NV S e A LQ TH ----------------- TTPEALIQEEQ AST I FQ SE QGK K TID IY WL F DDGGLTLL I PYLL HR KK R W G 837
Cdd:TIGR00930 711 EGL PI S - V LQ VQ eelendcsedsielndg KISTQPDMHLE AST Q FQ KK QGK G TID VW WL V DDGGLTLL L PYLL TT KK V W K 789
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 838 KCKIR V FVG G Q - IN R MDE E R K AIIS LL S KFR LGFHEVH VL P DIN Q KPQ A E HTKR FE D MI A PFRL NDGF KD EATVT - E M RR 915
Cdd:TIGR00930 790 KCKIR I FVG A Q k DD R SEQ E K K DMAT LL Y KFR IDAEVIV VL M DIN A KPQ T E SMEA FE E MI R PFRL HKTE KD REAKD p K M TW 869
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 916 DC PWKI S D E E INK N RI KS L RQVRL S E I LL D YSRDAAL II L T LP IG RKG KC P SS LYMAWLE T LS Q DL r PPVLL I RGN QE NV 995
Cdd:TIGR00930 870 TK PWKI T D A E LQS N VR KS Y RQVRL N E L LL E YSRDAAL VV L S LP VP RKG SI P DE LYMAWLE V LS E DL - PPVLL V RGN HR NV 948
....*
gi 247301365 996 LTFY C 1000
Cdd:TIGR00930 949 LTFY S 953
SLC12
pfam03522 Solute carrier family 12;
652-1000
1.21e-168
Solute carrier family 12;
Pssm-ID: 460955
Cd Length: 414
Bit Score: 499.45
E-value: 1.21e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 652 RPALVDF VSTF T Q N L SLMICGHV LI G PGK Q RVPELR l IASGH t K WL N KRKIKAFY SD V IAED LR S G V Q I L M QASGLG RM K 731
Cdd:pfam03522 1 RPALVDF AHLI T K N V SLMICGHV VK G RLS Q KLRSEL - QKKAY - R WL R KRKIKAFY AL V DGDN LR E G A Q A L L QASGLG KL K 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 732 PNIL VV G F K RN W QSAHPATV E D Y IG V L HDAFD FN Y G V CVM R MR EGL N VS EA LQ - TH T TPEA L IQ E EQA S ----------- 799
Cdd:pfam03522 79 PNIL LM G Y K SD W RTCDKEEL E E Y FN V I HDAFD LQ Y A V AIL R LP EGL D VS HL LQ d QD T EELG L GD E TNS S yaeqsseeqst 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 800 --------------------------------------------------------------- T I FQ SE Q G K K TID IY WL 816
Cdd:pfam03522 159 snskqdddksklskkdsnlslspdkstknpsgkdssksdklkkkspsiilrtasnekeilnni T Q FQ KK Q K K G TID VW WL 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 817 F DDGGLTLL I PY L L HRKKR W GK CK I RVF VG G - QINRMD EE RKAII SLLSKFR LGFHEVH V L PDI NQ KP QA E HT K R F EDM I 895
Cdd:pfam03522 239 Y DDGGLTLL L PY I L STRSK W SD CK L RVF AL G n RKDELE EE QRNMA SLLSKFR IDYSDLT V I PDI TK KP KK E TK K F F DEL I 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 896 A PFRL NDGF K D E ATV temrrdcp W KI S D E E INKNRI K SL RQ V RL S E I LL DY S R DA A LI IL TLP IG RKG KCPSS LYMAWLE 975
Cdd:pfam03522 319 E PFRL HEDD K E E ESA -------- E KI T D S E LEALKE K TN RQ L RL R E L LL EH S S DA N LI VM TLP MP RKG TVSAP LYMAWLE 390
410 420
....*....|....*....|....*
gi 247301365 976 TL SQ DL r PP V LL I RGNQ EN VLTFY C 1000
Cdd:pfam03522 391 TL TK DL - PP F LL V RGNQ TS VLTFY S 414
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
156-604
1.00e-33
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 135.41
E-value: 1.00e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 156 LP WIT A QAGIVLTW L II L LSVMVTSITG LS ISAISTN g KVKS GG T Y FLIS R S LGP E LG GSI G LIFAFANAVG VA MHT V G F 235
Cdd:COG0531 34 LP GLA A GLAGPAAI L AW L IAGLLALLVA LS YAELASA - FPRA GG A Y TYAR R A LGP L LG FLA G WALLLSYVLA VA AVA V A F 112
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 236 AETVRD L L qeygtpivd P INDIRI I GV V TVTV L LAIS L A G MEWES K AQVLFFLVIMVSFANYL V G tlipasedkask G FY 315
Cdd:COG0531 113 GGYLSS L F --------- P AGGSVL I AL V LILL L TLLN L R G VKESA K VNNILTVLKLLVLLLFI V V ------------ G LF 171
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 316 SYHGDI F v QNLV P DWR G ID G s FFGMFSIF F PSA TG IL A G AN ISGDL K D P AVA IP KGTLMAIFWTTIS Y LAI S ATIGSC V V 395
Cdd:COG0531 172 AFDPAN F - TPFL P AGG G LS G - VLAALALA F FAF TG FE A I AN LAEEA K N P KRN IP RAIILSLLIVGVL Y ILV S LALTGV V P 249
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 396 R D ASGDVNDTM tpgpgpceglacgygwnftecsqqrscrygliny YQTMSM V -- SAF A P LI TA G IFGAT L SSAL A CLVS A 473
Cdd:COG0531 250 Y D ELAASGAPL ---------------------------------- ADAAEA V fg PWG A I LI AL G ALLSL L GALN A SILG A 295
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 474 AKVFQCLCE D Q L Y P li GF F G K GYGKNRE PV RGY LL AY -- A IAVAFIII A ELNTI A PII S NFF L CS Y A L INFSCFHASITN 551
Cdd:COG0531 296 SRLLYAMAR D G L L P -- KV F A K VHPRFGT PV NAI LL TG vi A LLLLLLGA A SFTAL A SLA S VGV L LA Y L L VALAVIVLRRRR 373
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 247301365 552 SPGW RP s FR YYSKWAALF G AVISVVIMF LL TWW A A LI AIGVVLF - LLLY VI Y KK 604
Cdd:COG0531 374 PDLP RP - FR VPLPLIPIL G ILLCLFLLY LL GPG A L LI GLVLLAI g LLLY LL Y RR 426
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
57-1000
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1572.41
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 57 NT I D V VP AY EHY A NS ALP G E P RKV RP T L AD LH SF L - K EG S H L HA LA FDGRQ G RELTDGLVEDETGTNS EK S P GEP V R FGW 135
Cdd:TIGR00930 1 NT V D A VP RI EHY R NS EGQ G G P KRN RP S L EE LH DL L d K VV S L L GP LA DYTNN G QGMKEHEEAEDAEGTK EK P P AGA V K FGW 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 136 V K GV MIR C M LNIWGVIL Y LRL P WI TA QAGI V L TW LIILL SVM VT S ITGLS I SAI S TNG K VK S GG T Y F LISRSLGPE L GGS 215
Cdd:TIGR00930 81 V M GV LVP C L LNIWGVIL F LRL S WI VG QAGI G L SL LIILL CCC VT T ITGLS M SAI A TNG V VK G GG A Y Y LISRSLGPE F GGS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 216 IGLIFAFANAV G VAM HT VGFAETV R DLL Q E Y G TP I - VDPINDIRI I G V VTV T VLL A IS L AGMEWE S KAQVLF FLVIMV S F 294
Cdd:TIGR00930 161 IGLIFAFANAV A VAM YV VGFAETV L DLL R E N G SK I m VDPINDIRI Y G T VTV V VLL G IS F AGMEWE N KAQVLF LVIVLL S I 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 295 A N YL VGT L IPA S e DK AS KGF YSYHGD IF VQ N LV P DWR G ID G S FF GM F S IFFPS A TGILAGANISGDLKDP AV AIPKGTL M 374
Cdd:TIGR00930 241 L N IF VGT I IPA F - DK PA KGF FGLGNE IF SE N FI P GIP G PE G G FF SL F G IFFPS V TGILAGANISGDLKDP QK AIPKGTL L 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 375 AI FW TT IS YL AISATI G S CVVRDA S GD V NDT MTPG pgp C EGL AC gygwn F T EC SQQ r S C R YGL I N YY Q T MS M VS A F A PLI 454
Cdd:TIGR00930 320 AI LT TT VV YL GSVVLF G A CVVRDA T GD K NDT LVTN --- C TSA AC ----- F S EC AHN - T C S YGL M N NL Q V MS L VS P F P PLI 390
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 455 TAGIF G ATLSSALA C LVSA AKV FQ C LC E D QL YP LIG FFGKGYGKN R EP V R G YLL AYA IA VA FI I IAELNTIAPIISNFFL 534
Cdd:TIGR00930 391 TAGIF S ATLSSALA S LVSA PRL FQ A LC K D NI YP FLQ FFGKGYGKN G EP L R A YLL TAF IA EG FI L IAELNTIAPIISNFFL 470
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 535 C SYALINFSCFHAS ITN SPGWRP S F R YY SK W AA L F GA VISVV IMFL LT WWAAL I A IGVV LFL LL YV I YKKP E VNWGSS V Q 614
Cdd:TIGR00930 471 A SYALINFSCFHAS LLR SPGWRP R F K YY HW W LS L L GA SLCCA IMFL IS WWAAL V A MVIA LFL YK YV T YKKP D VNWGSS T Q 550
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 615 A G SY N LAL SYSVG L N EVEDH I KN Y RPQCLVLTGPP NF RPAL V DF V S T FT QNLS LMICG H V LI GP GKQR V P E LRLIASGHT 694
Cdd:TIGR00930 551 A L SY S LAL YSLLR L E EVEDH V KN W RPQCLVLTGPP VC RPAL L DF A S Q FT KGKG LMICG S V IQ GP RLEC V K E AQAAEAKIQ 630
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 695 K WL N K R K I KAFY SD V I A E DLR S GV QI L M QASGLGRMKPN I LV V G F K RN W QS A H P ATV E D YIG VL HDAFD FNYG V C V M R MR 774
Cdd:TIGR00930 631 T WL E K N K V KAFY AV V V A D DLR E GV RH L I QASGLGRMKPN T LV M G Y K KD W RQ A E P RAW E T YIG II HDAFD AHLA V V V V R NS 710
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 775 EGL NV S e A LQ TH ----------------- TTPEALIQEEQ AST I FQ SE QGK K TID IY WL F DDGGLTLL I PYLL HR KK R W G 837
Cdd:TIGR00930 711 EGL PI S - V LQ VQ eelendcsedsielndg KISTQPDMHLE AST Q FQ KK QGK G TID VW WL V DDGGLTLL L PYLL TT KK V W K 789
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 838 KCKIR V FVG G Q - IN R MDE E R K AIIS LL S KFR LGFHEVH VL P DIN Q KPQ A E HTKR FE D MI A PFRL NDGF KD EATVT - E M RR 915
Cdd:TIGR00930 790 KCKIR I FVG A Q k DD R SEQ E K K DMAT LL Y KFR IDAEVIV VL M DIN A KPQ T E SMEA FE E MI R PFRL HKTE KD REAKD p K M TW 869
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 916 DC PWKI S D E E INK N RI KS L RQVRL S E I LL D YSRDAAL II L T LP IG RKG KC P SS LYMAWLE T LS Q DL r PPVLL I RGN QE NV 995
Cdd:TIGR00930 870 TK PWKI T D A E LQS N VR KS Y RQVRL N E L LL E YSRDAAL VV L S LP VP RKG SI P DE LYMAWLE V LS E DL - PPVLL V RGN HR NV 948
....*
gi 247301365 996 LTFY C 1000
Cdd:TIGR00930 949 LTFY S 953
SLC12
pfam03522 Solute carrier family 12;
652-1000
1.21e-168
Solute carrier family 12;
Pssm-ID: 460955
Cd Length: 414
Bit Score: 499.45
E-value: 1.21e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 652 RPALVDF VSTF T Q N L SLMICGHV LI G PGK Q RVPELR l IASGH t K WL N KRKIKAFY SD V IAED LR S G V Q I L M QASGLG RM K 731
Cdd:pfam03522 1 RPALVDF AHLI T K N V SLMICGHV VK G RLS Q KLRSEL - QKKAY - R WL R KRKIKAFY AL V DGDN LR E G A Q A L L QASGLG KL K 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 732 PNIL VV G F K RN W QSAHPATV E D Y IG V L HDAFD FN Y G V CVM R MR EGL N VS EA LQ - TH T TPEA L IQ E EQA S ----------- 799
Cdd:pfam03522 79 PNIL LM G Y K SD W RTCDKEEL E E Y FN V I HDAFD LQ Y A V AIL R LP EGL D VS HL LQ d QD T EELG L GD E TNS S yaeqsseeqst 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 800 --------------------------------------------------------------- T I FQ SE Q G K K TID IY WL 816
Cdd:pfam03522 159 snskqdddksklskkdsnlslspdkstknpsgkdssksdklkkkspsiilrtasnekeilnni T Q FQ KK Q K K G TID VW WL 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 817 F DDGGLTLL I PY L L HRKKR W GK CK I RVF VG G - QINRMD EE RKAII SLLSKFR LGFHEVH V L PDI NQ KP QA E HT K R F EDM I 895
Cdd:pfam03522 239 Y DDGGLTLL L PY I L STRSK W SD CK L RVF AL G n RKDELE EE QRNMA SLLSKFR IDYSDLT V I PDI TK KP KK E TK K F F DEL I 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 896 A PFRL NDGF K D E ATV temrrdcp W KI S D E E INKNRI K SL RQ V RL S E I LL DY S R DA A LI IL TLP IG RKG KCPSS LYMAWLE 975
Cdd:pfam03522 319 E PFRL HEDD K E E ESA -------- E KI T D S E LEALKE K TN RQ L RL R E L LL EH S S DA N LI VM TLP MP RKG TVSAP LYMAWLE 390
410 420
....*....|....*....|....*
gi 247301365 976 TL SQ DL r PP V LL I RGNQ EN VLTFY C 1000
Cdd:pfam03522 391 TL TK DL - PP F LL V RGNQ TS VLTFY S 414
AA_permease
pfam00324 Amino acid permease;
138-643
4.16e-119
Amino acid permease;
Pssm-ID: 366028 [Multi-domain]
Cd Length: 467
Bit Score: 372.81
E-value: 4.16e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 138 G V MIRCMLNIW G VI L YLRLPWITA QAG IVLTW L II L L S VM V TSITG LS ISA ISTNG K V k SGG T Y FLI SR S LGP E LG GSI G 217
Cdd:pfam00324 1 H V QMIALGGVI G TG L FVGSGSVLG QAG PAGAL L GY L I S GV V IFLVM LS LGE ISTNG P V - SGG F Y TYA SR F LGP S LG FAT G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 218 L ------ I FAF A NAVGV A MHTVG F A E T V R D LLQEYGT pivdpindirii G V V TVTV L LA I S L A G ME W ESK A QVL F F L VIM 291
Cdd:pfam00324 80 W nywlsw I TVL A LELTA A SILIQ F W E L V P D IPYLWVW ------------ G A V FLVL L TI I N L V G VK W YGE A EFW F A L IKI 147
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 292 VSFANYLVGTL I PA S EDKASK G -- F YSYHGDIFVQ N LV P DW rgi DGS F FGM F S I F F PSA TGI LAGANIS G DL K D P AVA IP 369
Cdd:pfam00324 148 IAIIGFIIVGI I LL S GGNPND G ai F RYLGDNGGKN N FP P GF --- GKG F ISV F V I A F FAF TGI ELVGIAA G EV K N P EKS IP 224
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 370 K GT L MA I FWT TI S Y LAISAT IG SC V VRDAS G DV ND TMTP gpgpceglacgygwnftecsqqrscr YGLINYYQTMSMV S A 449
Cdd:pfam00324 225 K AI L QV I WRI TI F Y ILSLLA IG LL V PWNDP G LL ND SASA -------------------------- ASPFVIFFKFLGI S G 278
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 450 F APLI T A G I FG A T LS S A LAC L V S AAKVFQC L CE D Q L Y P lig F F G K GYG K NRE P V R GY L LAYA I AVAFIII A E LN TI ap I I 529
Cdd:pfam00324 279 L APLI N A V I LT A A LS A A NSS L Y S GSRMLYS L AR D G L A P --- K F L K KVD K RGV P L R AI L VSMV I SLLALLL A S LN PA -- I V 353
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 530 S NF F L CSYA L INFSCFHASITNSPGW R PS F R Y YSKWAALFGAVISVVIMFLLTWW AA L I A I GVVL FL LLYVIYKKPEV NW 609
Cdd:pfam00324 354 F NF L L AISG L SGLIVWGLISLSHLRF R KA F K Y QGRSIDELPFKAPLGPLGVILGL AA I I I I LIIQ FL YAFLPVPGGPK NW 433
490 500 510
....*....|....*....|....*....|....
gi 247301365 610 G SSVQ A GS Y NLA L SYSVG L NE V ED H I KN YR PQ C L 643
Cdd:pfam00324 434 G AGSF A AA Y LIV L LFLII L IG V KL H V KN WK PQ L L 467
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
156-604
1.00e-33
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 135.41
E-value: 1.00e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 156 LP WIT A QAGIVLTW L II L LSVMVTSITG LS ISAISTN g KVKS GG T Y FLIS R S LGP E LG GSI G LIFAFANAVG VA MHT V G F 235
Cdd:COG0531 34 LP GLA A GLAGPAAI L AW L IAGLLALLVA LS YAELASA - FPRA GG A Y TYAR R A LGP L LG FLA G WALLLSYVLA VA AVA V A F 112
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 236 AETVRD L L qeygtpivd P INDIRI I GV V TVTV L LAIS L A G MEWES K AQVLFFLVIMVSFANYL V G tlipasedkask G FY 315
Cdd:COG0531 113 GGYLSS L F --------- P AGGSVL I AL V LILL L TLLN L R G VKESA K VNNILTVLKLLVLLLFI V V ------------ G LF 171
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 316 SYHGDI F v QNLV P DWR G ID G s FFGMFSIF F PSA TG IL A G AN ISGDL K D P AVA IP KGTLMAIFWTTIS Y LAI S ATIGSC V V 395
Cdd:COG0531 172 AFDPAN F - TPFL P AGG G LS G - VLAALALA F FAF TG FE A I AN LAEEA K N P KRN IP RAIILSLLIVGVL Y ILV S LALTGV V P 249
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 396 R D ASGDVNDTM tpgpgpceglacgygwnftecsqqrscrygliny YQTMSM V -- SAF A P LI TA G IFGAT L SSAL A CLVS A 473
Cdd:COG0531 250 Y D ELAASGAPL ---------------------------------- ADAAEA V fg PWG A I LI AL G ALLSL L GALN A SILG A 295
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 474 AKVFQCLCE D Q L Y P li GF F G K GYGKNRE PV RGY LL AY -- A IAVAFIII A ELNTI A PII S NFF L CS Y A L INFSCFHASITN 551
Cdd:COG0531 296 SRLLYAMAR D G L L P -- KV F A K VHPRFGT PV NAI LL TG vi A LLLLLLGA A SFTAL A SLA S VGV L LA Y L L VALAVIVLRRRR 373
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 247301365 552 SPGW RP s FR YYSKWAALF G AVISVVIMF LL TWW A A LI AIGVVLF - LLLY VI Y KK 604
Cdd:COG0531 374 PDLP RP - FR VPLPLIPIL G ILLCLFLLY LL GPG A L LI GLVLLAI g LLLY LL Y RR 426
AA_permease_N
pfam08403 Amino acid permease N-terminal; This domain is found to the N-terminus of the amino acid ...
43-113
7.94e-33
Amino acid permease N-terminal; This domain is found to the N-terminus of the amino acid permease domain (pfam00324) in metazoan Na-K-Cl cotransporters.
Pssm-ID: 429977
Cd Length: 70
Bit Score: 121.39
E-value: 7.94e-33
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 247301365 43 L THGST L Y MR TFG Y NT I D V VP AYEH Y A N SALPGEPR K V RP T LA D LHS F LK EG S H L h A L A FDGRQ G R E LT DG 113
Cdd:pfam08403 1 D THGST Y Y LQ TFG H NT L D A VP RIDF Y R N TGSVSGVK K S RP S LA E LHS Q LK KN S A L - A V A EGSVD G V E NG DG 70
AA_permease_2
pfam13520 Amino acid permease;
163-601
1.38e-13
Amino acid permease;
Pssm-ID: 404414 [Multi-domain]
Cd Length: 427
Bit Score: 73.88
E-value: 1.38e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 163 A G IVLTWLIILLSVMVT S ITGLSIS A ISTNGKVK SGG T Y FLISRSL G PELGGSI G LIFA FA NAV G V A MHTVGF A ET vrd L 242
Cdd:pfam13520 27 S G GPALIVWGWIAAIIF S LAVGLVY A ELSSALPR SGG I Y VYLENAF G KFVAFLA G WSNW FA YVL G L A SSASVA A SY --- L 103
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 243 L QEY G TPI V DPINDIRI I GVVTVTVLLA I SLA G MEWES K A Q VLFFLVIMVSFANYLVGTLIPA sedk A SK G FYSYHGDIF 322
Cdd:pfam13520 104 L SAL G PDL V PTTWLTYG I AIAILIIFAI I NIR G VRESA K I Q NILGILKLLLPLILIIILGLVT ---- A DG G GFNLLSGEW 179
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 323 VQNLVPD W rgi D G S F F G MFSIFF p S A TG ILAG AN I S GDL K DPA V ai PK GTLMAIFWTTIS Y LAISATIGSC V VR D ASGDV 402
Cdd:pfam13520 180 HTFFPDG W --- P G V F A G FLGVLW - S F TG FESA AN V S EEV K KRN V -- PK AIFIGVIIVGVL Y ILVNIAFFGV V PD D EIALS 253
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 403 NDTMTPGP gpceglacgygwnftecsqqrscryglin YYQTMSMVSAF A PLITAGIFGAT L SSALACL V S A AKVFQC L CE 482
Cdd:pfam13520 254 SGLGQVAA ----------------------------- LLFQAVGGKWG A IIVVILLALSL L GAVNTAI V G A SRLLYA L AR 304
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 247301365 483 D QLY P LIG FF G K g YG K NRE P V R GYL L AY ----- AIAVAFIII A EL N TIAPIISNFF L C SY A L INFSCFHASITNSPGW R p 557
Cdd:pfam13520 305 D GVL P FSR FF A K - VN K FGS P I R AII L TA ilsli LLLLFLLSP A AY N ALLSLSAYGY L L SY L L PIIGLLILRKKRPDLG R - 382
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 247301365 558 sf RYYSKWA A L FG AVI S VVIMFL L TWWAALI A I G VV L FLLLYV I 601
Cdd:pfam13520 383 -- IPGRWPV A I FG ILF S LFLIVA L FFPPVGP A T G SS L NYAIIL I 424
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
