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Conserved domains on  [gi|254281343|ref|NP_061350|]
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1-acyl-sn-glycerol-3-phosphate acyltransferase alpha isoform 1 precursor [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 66-253 1.36e-56

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


:

Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 180.16  E-value: 1.36e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  66 LRLLLlhvkYLYGIRVEVRGAHHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGIIFID 145
Cdd:cd07989    1 LRLLL----RLLGVRVRVEGLENLPPKGPVIIVANHQSYLDPLVLGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPID 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343 146 RKRTGDAISVMSEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIIPIVMSSYQDFYSKKeRRFTSPG 225
Cdd:cd07989   77 RGNGRSAREALREAIE-ALKEGESVVIFPEGTRSRDGELLPFKSGAFRLAKEAGVPIVPVAISGTWGSLPKG-KKLPRPG 154

                        170       180       190
                 ....*....|....*....|....*....|
gi 254281343 226 RCQVRVLPPVSTEGL--TPDDVPALADSVR 253
Cdd:cd07989  155 RVTVRIGEPIPPEGLelAEEDRKELREKVR 184
 
Name Accession Description Interval E-value
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 66-253 1.36e-56

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 180.16  E-value: 1.36e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  66 LRLLLlhvkYLYGIRVEVRGAHHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGIIFID 145
Cdd:cd07989    1 LRLLL----RLLGVRVRVEGLENLPPKGPVIIVANHQSYLDPLVLGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPID 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343 146 RKRTGDAISVMSEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIIPIVMSSYQDFYSKKeRRFTSPG 225
Cdd:cd07989   77 RGNGRSAREALREAIE-ALKEGESVVIFPEGTRSRDGELLPFKSGAFRLAKEAGVPIVPVAISGTWGSLPKG-KKLPRPG 154

                        170       180       190
                 ....*....|....*....|....*....|
gi 254281343 226 RCQVRVLPPVSTEGL--TPDDVPALADSVR 253
Cdd:cd07989  155 RVTVRIGEPIPPEGLelAEEDRKELREKVR 184
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 64-266 4.63e-56

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 179.82  E-value: 4.63e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  64 KILRLLLLHVKYLYGIRVEVRGAHHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGIIF 143
Cdd:COG0204   14 RLVRLWARLLLRLLGVRVRVEGLENLPADGPVLIVANHQSWLDILLLLAALPRPVRFVAKKELFKIPLLGWLLRALGAIP 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343 144 IDRKRTGDAISVMSEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIIPIVMSSYQDFYSKKERRftS 223
Cdd:COG0204   94 VDRSKRRAALRALRQAVE-ALKAGESLVIFPEGTRSPDGRLLPFKTGAARLALEAGVPIVPVAIDGTERALPKGFLP--R 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 254281343 224 PGRCQVRVLPPVSTEGLTPDDVPALADSVRHSMLTIFREISTD 266
Cdd:COG0204  171 PGKVTVRIGPPIDPSDLEGEDRRELAERLRAAIEALLAELRAE 213
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
 80-208 2.58e-43

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 144.34  E-value: 2.58e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343   80 RVEVRGAHHFPPTQPYVVVSNHQSSLDLLGMMEVLPD---RCVPIAKRELLWAGSAGLACWLAGIIFIDRKRTGDAISVM 156
Cdd:pfam01553   1 RIEVHGLENLPRGGPAIVVANHQSYLDVLLLSLALYKrgrPLVFVAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 254281343  157 SEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIIPIVMS 208
Cdd:pfam01553  81 EYLVE-LLREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEAGVPIVPVAIS 131
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
 78-208 3.97e-40

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 135.94  E-value: 3.97e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343   78 GIRVEVRGAHHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGIIFIDRKRTgDAISVMS 157
Cdd:TIGR00530   1 GLKVEVVGPENLPAKSPVLVVANHQSNLDPLTLSAAFPPPIVFIAKKELKWIPFFGIMLWLTGAIFIDRENI-RAIATAL 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 254281343  158 EVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIIPIVMS 208
Cdd:TIGR00530  80 KAAIEVLKQGRSIGVFPEGTRSRGRDILPFKKGAFHIAIKAGVPILPVVLS 130
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
 95-208 1.78e-35

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 123.62  E-value: 1.78e-35
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343    95 YVVVSNHQSSLDLLGMMEVLPD---RCVPIAKRELLWAGSAGLACWLAGIIFIDRKRTGDAISVMSEVAQtLLTQDVRVW 171
Cdd:smart00563   1 ALVVANHQSFLDPLVLSALLPRklgRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKARAALREAVE-LLKEGEWLL 79

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 254281343   172 VFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIIPIVMS 208
Cdd:smart00563  80 IFPEGTRSRPGKLLPFKKGAARLALEAGVPIVPVAIR 116
PRK15018 PRK15018
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
 31-256 2.05e-27

1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional


Pssm-ID: 184979  Cd Length: 245  Bit Score: 106.64  E-value: 2.05e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  31 YFFKMAFYNGWILFLAILAIPVCAVRGRNVENMKILRLLLLHVKYLYGIRVEVRGAHHFPPTQPYVVVSNHQSSLDLLGM 110
Cdd:PRK15018   3 YIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGRLAPLFGLKVECRKPADAESYGNAIYIANHQNNYDMVTA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343 111 MEVLPDRCVPIAKRELLWAGSAGLACWLAGIIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRG 190
Cdd:PRK15018  83 SNIVQPPTVTVGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFKTG 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 254281343 191 AFHLAVQAQVPIIPIVMSSYQDfysKKERRFTSPGRCQVRVLPPVSTEGLTPDDVPALADSVRHSM 256
Cdd:PRK15018 163 AFHAAIAAGVPIIPVCVSTTSN---KINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELAAHCRSIM 225
 
Name Accession Description Interval E-value
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 66-253 1.36e-56

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 180.16  E-value: 1.36e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  66 LRLLLlhvkYLYGIRVEVRGAHHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGIIFID 145
Cdd:cd07989    1 LRLLL----RLLGVRVRVEGLENLPPKGPVIIVANHQSYLDPLVLGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPID 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343 146 RKRTGDAISVMSEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIIPIVMSSYQDFYSKKeRRFTSPG 225
Cdd:cd07989   77 RGNGRSAREALREAIE-ALKEGESVVIFPEGTRSRDGELLPFKSGAFRLAKEAGVPIVPVAISGTWGSLPKG-KKLPRPG 154

                        170       180       190
                 ....*....|....*....|....*....|
gi 254281343 226 RCQVRVLPPVSTEGL--TPDDVPALADSVR 253
Cdd:cd07989  155 RVTVRIGEPIPPEGLelAEEDRKELREKVR 184
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 64-266 4.63e-56

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 179.82  E-value: 4.63e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  64 KILRLLLLHVKYLYGIRVEVRGAHHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGIIF 143
Cdd:COG0204   14 RLVRLWARLLLRLLGVRVRVEGLENLPADGPVLIVANHQSWLDILLLLAALPRPVRFVAKKELFKIPLLGWLLRALGAIP 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343 144 IDRKRTGDAISVMSEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIIPIVMSSYQDFYSKKERRftS 223
Cdd:COG0204   94 VDRSKRRAALRALRQAVE-ALKAGESLVIFPEGTRSPDGRLLPFKTGAARLALEAGVPIVPVAIDGTERALPKGFLP--R 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 254281343 224 PGRCQVRVLPPVSTEGLTPDDVPALADSVRHSMLTIFREISTD 266
Cdd:COG0204  171 PGKVTVRIGPPIDPSDLEGEDRRELAERLRAAIEALLAELRAE 213
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
 80-208 2.58e-43

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 144.34  E-value: 2.58e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343   80 RVEVRGAHHFPPTQPYVVVSNHQSSLDLLGMMEVLPD---RCVPIAKRELLWAGSAGLACWLAGIIFIDRKRTGDAISVM 156
Cdd:pfam01553   1 RIEVHGLENLPRGGPAIVVANHQSYLDVLLLSLALYKrgrPLVFVAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 254281343  157 SEVAQtLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIIPIVMS 208
Cdd:pfam01553  81 EYLVE-LLREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEAGVPIVPVAIS 131
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
 78-208 3.97e-40

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 135.94  E-value: 3.97e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343   78 GIRVEVRGAHHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGIIFIDRKRTgDAISVMS 157
Cdd:TIGR00530   1 GLKVEVVGPENLPAKSPVLVVANHQSNLDPLTLSAAFPPPIVFIAKKELKWIPFFGIMLWLTGAIFIDRENI-RAIATAL 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 254281343  158 EVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIIPIVMS 208
Cdd:TIGR00530  80 KAAIEVLKQGRSIGVFPEGTRSRGRDILPFKKGAFHIAIKAGVPILPVVLS 130
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
 95-208 1.78e-35

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 123.62  E-value: 1.78e-35
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343    95 YVVVSNHQSSLDLLGMMEVLPD---RCVPIAKRELLWAGSAGLACWLAGIIFIDRKRTGDAISVMSEVAQtLLTQDVRVW 171
Cdd:smart00563   1 ALVVANHQSFLDPLVLSALLPRklgRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKARAALREAVE-LLKEGEWLL 79

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 254281343   172 VFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIIPIVMS 208
Cdd:smart00563  80 IFPEGTRSRPGKLLPFKKGAARLALEAGVPIVPVAIR 116
PRK15018 PRK15018
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
 31-256 2.05e-27

1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional


Pssm-ID: 184979  Cd Length: 245  Bit Score: 106.64  E-value: 2.05e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  31 YFFKMAFYNGWILFLAILAIPVCAVRGRNVENMKILRLLLLHVKYLYGIRVEVRGAHHFPPTQPYVVVSNHQSSLDLLGM 110
Cdd:PRK15018   3 YIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGRLAPLFGLKVECRKPADAESYGNAIYIANHQNNYDMVTA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343 111 MEVLPDRCVPIAKRELLWAGSAGLACWLAGIIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRG 190
Cdd:PRK15018  83 SNIVQPPTVTVGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFKTG 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 254281343 191 AFHLAVQAQVPIIPIVMSSYQDfysKKERRFTSPGRCQVRVLPPVSTEGLTPDDVPALADSVRHSM 256
Cdd:PRK15018 163 AFHAAIAAGVPIIPVCVSTTSN---KINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELAAHCRSIM 225
LPLAT cd06551
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ...
 67-208 2.68e-18

Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).


Pssm-ID: 153244 [Multi-domain]  Cd Length: 187  Bit Score: 80.54  E-value: 2.68e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  67 RLLLLHvkYLYGIRVEVRGAHHFPPTQPYVVVSNHQSSLDLLgMMEVLPDRcvpIAKRELLWAGSA--GLACWL---AGI 141
Cdd:cd06551    2 RYLLLN--FFGFVRLEVKGPPPPPGGGPVLFVSNHSSWWDGL-ILFLLLER---GLRRDVYGLMDEelLERYPFftrLGA 75

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 254281343 142 IFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTRNHNGS-MLPFKRGAFHLAVQAQVPIIPIVMS 208
Cdd:cd06551   76 FSVDRDSPRSAAKSLKYVARLLSKPGSVVWIFPEGTRTRRDKrPLQFKPGVAHLAEKAGVPIVPVALR 143
PLN02901 PLN02901
1-acyl-sn-glycerol-3-phosphate acyltransferase
 80-244 2.75e-16

1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 215488 [Multi-domain]  Cd Length: 214  Bit Score: 75.54  E-value: 2.75e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  80 RVEVRGAHHFP-PTQPYVVVSNHQSSLDLLGMMEVlpDRCVP-IAKRELLWAGSAGLACWLAGIIFIdrKRTgDAISVMS 157
Cdd:PLN02901  36 KIEVEGLENLPsPDEPAVYVSNHQSFLDIYTLFHL--GRPFKfISKTSIFLIPIIGWAMYMTGHIPL--KRM-DRRSQLE 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343 158 EVAQT--LLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIIPIV-MSSYQDFYSKKERRFtSPGRCQVRVLPP 234
Cdd:PLN02901 111 CLKRCmeLLKKGASVFFFPEGTRSKDGKLAAFKKGAFSVAAKTGVPVVPITlVGTGKIMPNGKEGIL-NPGSVKVVIHPP 189

                        170
                 ....*....|
gi 254281343 235 VstEGLTPDD 244
Cdd:PLN02901 190 I--EGSDADE 197
LPLAT_LCLAT1-like cd07990
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ...
 75-178 7.87e-14

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins.


Pssm-ID: 153252 [Multi-domain]  Cd Length: 193  Bit Score: 68.42  E-value: 7.87e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  75 YLYGIRVEVRGAHHFPPTQPYVVVSNHQSSLD-LLGMMEVLPDRCVP----IAKRELLWAGSAGLACWLAGIIFIDRKRT 149
Cdd:cd07990    6 WLSGVKVVVYGDEPKLPKERALIISNHRSEVDwLVLWMLADRFGRLGrlkiVLKDSLKYPPLGGWGWQLGEFIFLKRKWE 85

                         90       100       110
                 ....*....|....*....|....*....|.
gi 254281343 150 GDAIsVMSEVAQTLLTQDVRVWV--FPEGTR 178
Cdd:cd07990   86 KDEK-TIKRQLKRLKDSPEPFWLliFPEGTR 115
LPLAT_LPCAT1-like cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ...
 78-256 2.70e-13

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.


Pssm-ID: 153253 [Multi-domain]  Cd Length: 211  Bit Score: 67.25  E-value: 2.70e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  78 GIRVEVRGAHHfPPTQPYVVVSNHQSSLDLLGMMEVLPdrCVPIAKRELLWAGSAGLACWLAGIIFIDRKRTGDAISVMS 157
Cdd:cd07991   10 FYVIKVHGKPD-PPEAPRIIVANHTSFIDPLILFSDLF--PSIVAKKELGKLPFIGTILRALGCIFVDRSEPKDRKKVVE 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343 158 EVAQTLLTQDVR-VWVFPEGTRNHNGSMLPFKRGAFhlavQAQVPIIPIVM----------------SSYQDFYskkeRR 220
Cdd:cd07991   87 EIKERATDPNWPpILIFPEGTTTNGKALIMFKKGAF----EPGVPVQPVAIrypnkfvdafwnssgySSLMYLF----RL 158

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 254281343 221 FTSPG-RCQVRVLPPV--STEGLTPDdvpALADSVRHSM 256
Cdd:cd07991  159 LTQPAnVLEVEFLPVYtpSEEGEDPK---EFANRVRLIM 194
LPLAT_AAK14816-like cd07992
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 66-258 5.74e-10

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.


Pssm-ID: 153254 [Multi-domain]  Cd Length: 203  Bit Score: 57.66  E-value: 5.74e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  66 LRLLLLHVKYLYGIRVEVRGAHHFPPTQPYVVVSNHQSSL-DLLGMMEVLPDRCVPIAKRELLWAGSAGLACWLAGIIFI 144
Cdd:cd07992    1 VRLLSRVILRIYFRRITVVGRENVPKDGPVIFLGNHPNALiDPLLLAATLRRPVRFLAKADLFKNPLIGWLLESFGAIPV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343 145 DRKR----TGDAIS----VMSEVAQTLLTQDvRVWVFPEGTrNHNGS-MLPFKRGAFHLAVQA------QVPIIPIVMss 209
Cdd:cd07992   81 YRPKdlarGGIGKIsnaaVFDAVGEALKAGG-AIGIFPEGG-SHDRPrLLPLKAGAARMALEAleagqkDVKIVPVGL-- 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 254281343 210 yqdFYSKKErRFtsPGRCQVRVLPPVSTEGLTPDDVPALADSVRHSMLT 258
Cdd:cd07992  157 ---NYEDKS-RF--RSRVLVEFGKPISVSAFEEAEASRDVEKKLINQLE 199
PRK08633 PRK08633
2-acyl-glycerophospho-ethanolamine acyltransferase; Validated
 42-204 9.34e-09

2-acyl-glycerophospho-ethanolamine acyltransferase; Validated


Pssm-ID: 236315 [Multi-domain]  Cd Length: 1146  Bit Score: 56.09  E-value: 9.34e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343   42 ILFLAILAIPVCAVRGRNVEN--MKILRLLLLHVKYlygiRVEVRGAHHFPPTQPYVVVSNHQSSLD--LLGMMEVLPDR 117
Cdd:PRK08633  392 FYLIALVTLIGTLYTLLLLPDslLRFLLLLLMHTRY----RLRVEGRENIPAKGGALLLGNHVSWIDwaLLQAASPRPIR 467

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  118 CV---PIAKRELLwagsaglaCWLA---GIIFIDRKRTGDAISVMSEvaqtLLTQDVRVWVFPEGTRNHNGSMLPFKRGa 191
Cdd:PRK08633  468 FVmerSIYEKWYL--------KWFFklfGVIPISSGGSKESLEFIRK----ALDDGEVVCIFPEGAITRNGQLNEFKRG- 534

                         170
                  ....*....|....
gi 254281343  192 FHLAVQ-AQVPIIP 204
Cdd:PRK08633  535 FELIVKgTDVPIIP 548
LPLAT_ABO13168-like cd07988
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 90-249 4.12e-07

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Acinetobacter baumannii ATCC 17978 locus ABO13168 putative acyltransferase, and similar proteins.


Pssm-ID: 153250 [Multi-domain]  Cd Length: 163  Bit Score: 48.75  E-value: 4.12e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  90 PPTQP-YVV-VSNHQSSLDLLGMMEVLPDRCVPI---AKRELLWAGSAGLACWLaGIIFIDRKRTGDAISVMSEVAQTll 164
Cdd:cd07988   16 PPNKPkFVViGAPHTSNWDFVLGLLAAFALGLKIsflGKHSLFKPPLGPFMRWL-GGIPVDRSRAGGLVEQVVEEFRR-- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343 165 tQDVRVWVF-PEGTRNHNGsmlPFKRGAFHLAVQAQVPIIPivmsSYQDfYSKKErrftspgrcqVRVLPPVSTEGLTPD 243
Cdd:cd07988   93 -REEFVLAIaPEGTRSKVD---KWKTGFYHIARGAGVPILL----VYLD-YKRKT----------VGIGPLFEPSGDIEA 153


                 ....*.
gi 254281343 244 DVPALA 249
Cdd:cd07988  154 DLAAIR 159
LPLAT_DHAPAT-like cd07993
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ...
 139-236 8.02e-07

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.


Pssm-ID: 153255 [Multi-domain]  Cd Length: 205  Bit Score: 48.72  E-value: 8.02e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343 139 AGIIFIDRKRTGDAI--SVMSEVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRG-------AFHLAVQAQVPIIPIVMsS 209
Cdd:cd07993   71 LGAFFIRRSFGKDPLyrAVLQEYVQELLKNGQPLEFFIEGTRSRTGKLLPPKLGllsvvveAYLKGSVPDVLIVPVSI-S 149

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 254281343 210 Y-----QDFYS------KKERRFTSP------------GRCQVRVLPPVS 236
Cdd:cd07993  150 YdrvleEELYAeellgpPKPKESLSGllgaskilrenfGRIRVDFGEPIS 199
PRK14014 PRK14014
putative acyltransferase; Provisional
 74-146 1.07e-06

putative acyltransferase; Provisional


Pssm-ID: 237584 [Multi-domain]  Cd Length: 301  Bit Score: 49.08  E-value: 1.07e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 254281343  74 KYLYGIRVEVRGAHHFPPTQPYVVVSNHQSSLDLLGMMEVLPDRcVPI----AKRELLWAGSAGLACWLAGIIFIDR 146
Cdd:PRK14014  68 RLLPRTQWDVEGLEGLSKKGWYLVISNHQSWVDILVLQYVFNRR-IPMlkffLKQELIWVPFLGLAWWALDFPFMKR 143
PRK06814 PRK06814
acyl-[ACP]--phospholipid O-acyltransferase;
33-235 6.75e-06

acyl-[ACP]--phospholipid O-acyltransferase;


Pssm-ID: 235865 [Multi-domain]  Cd Length: 1140  Bit Score: 47.27  E-value: 6.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343   33 FKMAFYNGWILFL-----AILAIPVCAVRGRNVenMK-ILRLLLlhvKYLYgiRVEVRGAHHFPPTQP-YVVVSNHQSSL 105
Cdd:PRK06814  394 QALGFSIPWIILFialanLIVAILILRLLPTNL--LRdIFSILF---RAFY--RVEVKGLENLQKAGKkAVIAANHVSFL 466

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  106 DLLGMMEVLPDRCV-----PIAKRellWagsaglacWLAGIIFIDRKRTGDAISVMSevAQTL---LTQDVRVWVFPEGT 177
Cdd:PRK06814  467 DGPLLAAYLPEEPTfaidtDIAKA---W--------WVKPFLKLAKALPVDPTNPMA--TRTLikeVQKGEKLVIFPEGR 533

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 254281343  178 RNHNGSMLPFKRGAFHLAVQAQVPIIPIVMS----SYQDFYSKKERRFTSPgRCQVRVLPPV 235
Cdd:PRK06814  534 ITVTGSLMKIYDGPGMIADKAGAMVVPVRIDglqfTHFSRLKNQVRRKWFP-KVTVTILPPV 594
COG3176 COG3176
Putative hemolysin [General function prediction only];
76-207 6.20e-05

Putative hemolysin [General function prediction only];


Pssm-ID: 442409  Cd Length: 270  Bit Score: 43.49  E-value: 6.20e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  76 LYGIRVEV--RGAHHFPPTQPYVVVSNHQ-SSLDLLGMMEVL----PD-RCVPiakRELLWAGSAGLACwlAGIIFIDRk 147
Cdd:COG3176   52 ELGARLEVpeGDLDRIDADGHLLVVANHPlGILDGLALLKLVgtvrPDyRILA---NDLALRIPGGFYS--ELEFPVDP- 125

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 254281343 148 rtgDAISVMSEVAQTLLtQDVRVWVFPEGTRNHNGS--MLPFKRGAFHLAVQAQVPIIPIVM 207
Cdd:COG3176  126 ---FNLETLKAARRHLL-EGGRSCVFPAGRVSGARRviDLLWSGLAAKLARKAGAPVVPVYF 183
LPLAT_ACT14924-like cd07986
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 79-205 6.58e-05

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Pectobacterium carotovorum subsp. carotovorum PC1 locus ACT14924 putative acyltransferase, and similar proteins.


Pssm-ID: 153248 [Multi-domain]  Cd Length: 210  Bit Score: 43.00  E-value: 6.58e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  79 IRVEVRGAHHFPPTQPYVVVSNHQ-SSLDLLGMMEVL----PDrcVPIAKRELLWAGSAgLACWLAGIIFIDRKRTGD-A 152
Cdd:cd07986    8 LEVDVSGLENIPKDGPVVIVANHPfGILDGLILADLLgsvrPD--VRILANQLLSKIPE-LRDLFIPVDPLEGRAALAkN 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 254281343 153 ISVMSEvAQTLLTQDVRVWVFPEGT-----RNHNGSM-LPFKRGAFHLAVQAQVPIIPI 205
Cdd:cd07986   85 RESLRE-ALRHLKNGGALIIFPAGRvstasPPFGRVSdRPWNPFVARLARKAKAPVVPV 142
LPLAT_MGAT-like cd07987
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; ...
 82-233 1.43e-03

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.


Pssm-ID: 153249 [Multi-domain]  Cd Length: 212  Bit Score: 39.19  E-value: 1.43e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  82 EVRGAHHFPPTQPYVVVSNHqssldllGMMevLPDRCVPIAKRELLWAG----SAGLACWLAGIIFIDRKRTGDAISVMS 157
Cdd:cd07987    9 EVRGLENIPDEGPALLVHPH-------GGL--PIDGALLAAAFLLLFPGrlprALADHFLFPLPGLRDLLRRLGAVPGSR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343 158 EVAQTLLTQDVRVWVFPEGTR-------NHNGSMLPFKRGAFHLAVQAQVPIIPIVMSSYQDFYSKKERRFTSPGRCQVR 230
Cdd:cd07987   80 ENCVRLLREGELVLIFPGGARealkskrEEYYLLWKKRKGFARLALRAGAPIVPVFTFGEEELFRVLGDPDGPVGKRLFR 159


                 ...
gi 254281343 231 VLP 233
Cdd:cd07987  160 LLP 162
PLN02833 PLN02833
glycerol acyltransferase family protein
 22-202 7.74e-03

glycerol acyltransferase family protein


Pssm-ID: 215447  Cd Length: 376  Bit Score: 37.45  E-value: 7.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  22 LWFCSSSAKYF--FKMAF---YNGWILFLAiLAIPVCAVRGRNVENMKILRLLllhVKYLYGIRVEVRGA---HHFP-PT 92
Cdd:PLN02833  85 LWCVGVVIRYGilFPVRVlllAIGWIIFLS-AFIPVHFLLKGHKLRKKIERKL---VELICSAFVASWTGvikYHGPrPS 160

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254281343  93 Q--PYVVVSNHQSSLDLLGMMEVLPdrCVPIAKRELLWAG---SAGLACwlAGIIFIDRKRTGDaisvmSEVAQTLLTQD 167
Cdd:PLN02833 161 RrpKQVFVANHTSMIDFIVLEQMTP--FAVIMQKHPGWVGflqNTILES--VGCIWFNRTEAKD-----REVVAKKLRDH 231

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 254281343 168 VR------VWVFPEGTRNHNGSMLPFKRGAFHLAVQAqVPI 202
Cdd:PLN02833 232 VQdpdrnpLLIFPEGTCVNNEYTVMFKKGAFELGCTV-CPI 271
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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