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Conserved domains on  [gi|257153450|ref|NP_059086|]
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semenogelin I precursor [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Semenogelin super family cl28737
Semenogelin; This family consists of several mammalian secreted seminal proteins including ...
 5-88 1.93e-04

Semenogelin; This family consists of several mammalian secreted seminal proteins including semenogelin I and II. Freshly ejaculated human semen has the appearance of a loose gel in which the predominant structural protein components are the seminal vesicle secreted semenogelins (Sg). This family also includes seminal vesicle secretory protein 3A from mouse, which has been shown to be involved in the coagulation of semen resulting in the formation of the copulatory plug.


The actual alignment was detected with superfamily member pfam05474:

Pssm-ID: 368458 [Multi-domain]  Cd Length: 582  Bit Score: 43.33  E-value: 1.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257153450    5 VFVLSLLLILERQSAVVGQYGATKGHFQSSSSEgFMLGQKGRLSFGIKGGSDEAAEESLFMQsqrRVYGQGGGDMTQTRV 84
Cdd:pfam05474   6 LFVLSLLLILEKQAAVMGQKGGSKGQLPSGSSQ-FPHGQKGQHYFGQKDQQHTKSKGSFSIQ---HTYHVDINDHDWTRK 81


                  ....
gi 257153450   85 SQEH 88
Cdd:pfam05474  82 SQQY 85
 
Name Accession Description Interval E-value
Semenogelin pfam05474
Semenogelin; This family consists of several mammalian secreted seminal proteins including ...
 5-88 1.93e-04

Semenogelin; This family consists of several mammalian secreted seminal proteins including semenogelin I and II. Freshly ejaculated human semen has the appearance of a loose gel in which the predominant structural protein components are the seminal vesicle secreted semenogelins (Sg). This family also includes seminal vesicle secretory protein 3A from mouse, which has been shown to be involved in the coagulation of semen resulting in the formation of the copulatory plug.


Pssm-ID: 368458 [Multi-domain]  Cd Length: 582  Bit Score: 43.33  E-value: 1.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257153450    5 VFVLSLLLILERQSAVVGQYGATKGHFQSSSSEgFMLGQKGRLSFGIKGGSDEAAEESLFMQsqrRVYGQGGGDMTQTRV 84
Cdd:pfam05474   6 LFVLSLLLILEKQAAVMGQKGGSKGQLPSGSSQ-FPHGQKGQHYFGQKDQQHTKSKGSFSIQ---HTYHVDINDHDWTRK 81


                  ....
gi 257153450   85 SQEH 88
Cdd:pfam05474  82 SQQY 85
 
Name Accession Description Interval E-value
Semenogelin pfam05474
Semenogelin; This family consists of several mammalian secreted seminal proteins including ...
 5-88 1.93e-04

Semenogelin; This family consists of several mammalian secreted seminal proteins including semenogelin I and II. Freshly ejaculated human semen has the appearance of a loose gel in which the predominant structural protein components are the seminal vesicle secreted semenogelins (Sg). This family also includes seminal vesicle secretory protein 3A from mouse, which has been shown to be involved in the coagulation of semen resulting in the formation of the copulatory plug.


Pssm-ID: 368458 [Multi-domain]  Cd Length: 582  Bit Score: 43.33  E-value: 1.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257153450    5 VFVLSLLLILERQSAVVGQYGATKGHFQSSSSEgFMLGQKGRLSFGIKGGSDEAAEESLFMQsqrRVYGQGGGDMTQTRV 84
Cdd:pfam05474   6 LFVLSLLLILEKQAAVMGQKGGSKGQLPSGSSQ-FPHGQKGQHYFGQKDQQHTKSKGSFSIQ---HTYHVDINDHDWTRK 81


                  ....
gi 257153450   85 SQEH 88
Cdd:pfam05474  82 SQQY 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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