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Conserved domains on  [gi|6678003|ref|NP_033226|]
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excitatory amino acid transporter 4 [Mus musculus]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
51-530 2.71e-120

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 360.58  E-value: 2.71e-120
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   51 RRNAFILLTVSAVIIGVSLAFALRPYQLSYrqikyFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAA 129
Cdd:COG1301   1 FKLSLTLQILIALVLGILLGLLLPELVAAV-----LKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  130 VYYMVTTVIAVFIGILMVTIIHPGKGSKEGLHREGRIETVPTADaFMDLVRNMFPPNLVEAcfkqfktqystrvvtrtiv 209
Cdd:COG1301  76 LYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------- 135

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  210 rtdngselgasmsptssvenetsilenvtralgtlqevisfeetvpvpgSANGiNALGLVVFSVAFGLVIGGMKHKGRVL 289
Cdd:COG1301 136 -------------------------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPL 165

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  290 RDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMeDMAVLGgQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFP 369
Cdd:COG1301 166 LDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLK 243

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  370 FIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQIT 449
Cdd:COG1301 244 FLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQL 323

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  450 TISITATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHlSQRELELQEA 529
Cdd:COG1301 324 TIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK-WEGELDREKL 402


                .
gi 6678003  530 E 530
Cdd:COG1301 403 N 403
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
51-530 2.71e-120

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 360.58  E-value: 2.71e-120
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   51 RRNAFILLTVSAVIIGVSLAFALRPYQLSYrqikyFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAA 129
Cdd:COG1301   1 FKLSLTLQILIALVLGILLGLLLPELVAAV-----LKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  130 VYYMVTTVIAVFIGILMVTIIHPGKGSKEGLHREGRIETVPTADaFMDLVRNMFPPNLVEAcfkqfktqystrvvtrtiv 209
Cdd:COG1301  76 LYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------- 135

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  210 rtdngselgasmsptssvenetsilenvtralgtlqevisfeetvpvpgSANGiNALGLVVFSVAFGLVIGGMKHKGRVL 289
Cdd:COG1301 136 -------------------------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPL 165

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  290 RDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMeDMAVLGgQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFP 369
Cdd:COG1301 166 LDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLK 243

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  370 FIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQIT 449
Cdd:COG1301 244 FLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQL 323

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  450 TISITATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHlSQRELELQEA 529
Cdd:COG1301 324 TIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK-WEGELDREKL 402


                .
gi 6678003  530 E 530
Cdd:COG1301 403 N 403
SDF pfam00375
Sodium:dicarboxylate symporter family;
55-519 3.29e-113

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 341.81  E-value: 3.29e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003     55 FILLTVSAVIIGVSLAFALRPYqlsyrqIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVYYM 133
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPEL------AAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003    134 VTTVIAVFIGILMVTIIHPGKGSKeGLHREGRIETVPTADAFMDLVRNMFPPNLVEACFKQfktqystrvvtrtivrtdn 213
Cdd:pfam00375  75 VTTAIAALIGLLVANVFQPGSGLA-LIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEG------------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003    214 gselgasmsptssvenetsilenvtralgtlqevisfeetvpvpgsangiNALGLVVFSVAFGLVIGGMKHKGRVLRDFF 293
Cdd:pfam00375 135 --------------------------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFI 164

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003    294 DSLNEAIMRLVGIIIWYAPVGILFLIAGKILEmEDMAVLGgQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFPFIGG 373
Cdd:pfam00375 165 ESLQEVMMKVIGWVMKLAPIGVFALIANTVGT-YGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKK 242

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003    374 MLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISI 453
Cdd:pfam00375 243 MLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVL 322

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6678003    454 TATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHL 519
Cdd:pfam00375 323 TATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 60-516 1.47e-40

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 152.13  E-value: 1.47e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003    60 VSAVIIGVSLAFALRPYQLSYRQIkyfsfpGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVYYMVTTVI 138
Cdd:PRK13027  13 VIALVLGVALGAFFPHFAESLKPL------GDGFIKLIKMLIGPIVFCVVVSGIAGAgDLKKVGRVGLKAVIYFEVMTTI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   139 AVFIGILMVTIIHPGKGskeglhregrietvptadAFMDLvrnmfppnlveacfkqfktqystrvvtrtivRTDNGSELG 218
Cdd:PRK13027  87 ALVIGLVLAYLTGPGVG------------------MNIDL-------------------------------RSLDAASLA 117

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   219 ASMSPTSSVENETSILENVTralgtlqevisfeETVPVPGSANGiNALGLVVFSVAFGLVIGGMKHKGRVLRDFFDSLNE 298
Cdd:PRK13027 118 GYAKNAQSLKGTAGFLLKLI-------------PTTAVDAFAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSH 183

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   299 AIMRLVGIIIWYAPVGILFLIA---GKiLEMEDMAVLGGQLGMYTLTVIVGLFLHAGGVLPLIYFLVthrnpFPFIGGML 375
Cdd:PRK13027 184 VLFRIMGFIIKLAPLGVLGAIAfttGK-YGVGSLKQLGMLVAVFYLTCFVFVVVVLGAVMRLAGFSV-----FKLIRYLR 257

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   376 QALITAMGTSSSSATLPITFRCLEEgLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISITA 455
Cdd:PRK13027 258 EELLIVLGTASSDAVLPQVMRKLEH-MGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVS 336

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6678003   456 TAASVGAAGIPQAGLVTMVIVLTSVG-LPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVI 516
Cdd:PRK13027 337 LVTSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGNCVATVVV 398
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
51-530 2.71e-120

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 360.58  E-value: 2.71e-120
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   51 RRNAFILLTVSAVIIGVSLAFALRPYQLSYrqikyFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAA 129
Cdd:COG1301   1 FKLSLTLQILIALVLGILLGLLLPELVAAV-----LKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTL 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  130 VYYMVTTVIAVFIGILMVTIIHPGKGSKEGLHREGRIETVPTADaFMDLVRNMFPPNLVEAcfkqfktqystrvvtrtiv 209
Cdd:COG1301  76 LYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA------------------- 135

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  210 rtdngselgasmsptssvenetsilenvtralgtlqevisfeetvpvpgSANGiNALGLVVFSVAFGLVIGGMKHKGRVL 289
Cdd:COG1301 136 -------------------------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPL 165

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  290 RDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMeDMAVLGgQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFP 369
Cdd:COG1301 166 LDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKY-GLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLK 243

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  370 FIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQIT 449
Cdd:COG1301 244 FLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQL 323

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  450 TISITATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHlSQRELELQEA 529
Cdd:COG1301 324 TIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK-WEGELDREKL 402


                .
gi 6678003  530 E 530
Cdd:COG1301 403 N 403
SDF pfam00375
Sodium:dicarboxylate symporter family;
55-519 3.29e-113

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 341.81  E-value: 3.29e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003     55 FILLTVSAVIIGVSLAFALRPYqlsyrqIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVYYM 133
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPEL------AAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYFL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003    134 VTTVIAVFIGILMVTIIHPGKGSKeGLHREGRIETVPTADAFMDLVRNMFPPNLVEACFKQfktqystrvvtrtivrtdn 213
Cdd:pfam00375  75 VTTAIAALIGLLVANVFQPGSGLA-LIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEG------------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003    214 gselgasmsptssvenetsilenvtralgtlqevisfeetvpvpgsangiNALGLVVFSVAFGLVIGGMKHKGRVLRDFF 293
Cdd:pfam00375 135 --------------------------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFI 164

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003    294 DSLNEAIMRLVGIIIWYAPVGILFLIAGKILEmEDMAVLGgQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRNPFPFIGG 373
Cdd:pfam00375 165 ESLQEVMMKVIGWVMKLAPIGVFALIANTVGT-YGLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKK 242

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003    374 MLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISI 453
Cdd:pfam00375 243 MLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVL 322

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6678003    454 TATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHL 519
Cdd:pfam00375 323 TATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 60-516 1.47e-40

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 152.13  E-value: 1.47e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003    60 VSAVIIGVSLAFALRPYQLSYRQIkyfsfpGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVYYMVTTVI 138
Cdd:PRK13027  13 VIALVLGVALGAFFPHFAESLKPL------GDGFIKLIKMLIGPIVFCVVVSGIAGAgDLKKVGRVGLKAVIYFEVMTTI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   139 AVFIGILMVTIIHPGKGskeglhregrietvptadAFMDLvrnmfppnlveacfkqfktqystrvvtrtivRTDNGSELG 218
Cdd:PRK13027  87 ALVIGLVLAYLTGPGVG------------------MNIDL-------------------------------RSLDAASLA 117

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   219 ASMSPTSSVENETSILENVTralgtlqevisfeETVPVPGSANGiNALGLVVFSVAFGLVIGGMKHKGRVLRDFFDSLNE 298
Cdd:PRK13027 118 GYAKNAQSLKGTAGFLLKLI-------------PTTAVDAFAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSH 183

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   299 AIMRLVGIIIWYAPVGILFLIA---GKiLEMEDMAVLGGQLGMYTLTVIVGLFLHAGGVLPLIYFLVthrnpFPFIGGML 375
Cdd:PRK13027 184 VLFRIMGFIIKLAPLGVLGAIAfttGK-YGVGSLKQLGMLVAVFYLTCFVFVVVVLGAVMRLAGFSV-----FKLIRYLR 257

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   376 QALITAMGTSSSSATLPITFRCLEEgLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISITA 455
Cdd:PRK13027 258 EELLIVLGTASSDAVLPQVMRKLEH-MGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVS 336

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6678003   456 TAASVGAAGIPQAGLVTMVIVLTSVG-LPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVI 516
Cdd:PRK13027 337 LVTSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGNCVATVVV 398
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 62-516 1.18e-37

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 144.14  E-value: 1.18e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003    62 AVIIGVSLAFALRpYQLSYRQ---IKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVYYMVTTV 137
Cdd:PRK11283  15 ALVLGILLGAYLH-YHSDSRDwlvSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVITT 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   138 IAVFIGILMVTIIHPGKGSKEGL--------HREGRIETVPTADAFMDLVRNMFPPNLVeacfkqfktqystrvvtrtiv 209
Cdd:PRK11283  94 VAIILGITLANVFQPGAGIDMSQlatvdiskYQSTTEEVQSHSHGLMGTILSLIPTNIF--------------------- 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   210 rtdngselgASMsptssvenetsilenvtrALGtlqevisfeETVPVpgsanginalglVVFSVAFGLVIGGMKHKGRV- 288
Cdd:PRK11283 153 ---------ASM------------------AKG---------EMLPI------------IFFSVLFGLGLSSLPATHREp 184

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   289 LRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLggQLGMYTLTVIVGLFLHAGGVLPLIYFLVTHRnPF 368
Cdd:PRK11283 185 LVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLW--PLAKLVLLVYFAILFFALVVLGIVARLCGLS-IW 261

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   369 PFIGGMLQALITAMGTSSSSATLPitfRCLE--EGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLG 446
Cdd:PRK11283 262 ILIRILKDELILAYSTASSETVLP---RIIEkmEAYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIW 338

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   447 QITTISITATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVI 516
Cdd:PRK11283 339 QEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVI 408
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 90-532 2.26e-37

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 143.12  E-value: 2.26e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003    90 GELLMRMLQMLVLPLIVSSLVTGMASL-DNKATGRMGMRAAVYYMVTTVIAVFIGILMVTIIHPGKGskeglhregriet 168
Cdd:PRK01663  38 GDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKALLYFEIVSTIALIIGLIVVNVVQPGAG------------- 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   169 vptadafmdlvRNMFPPNLVEACFKQFktqystrvvtrtivrTDNGSELGAsmsptssvenetsilenvtraLGTLQEVI 248
Cdd:PRK01663 105 -----------MNIDPATLDAKAVAQY---------------AAQAHEQGT---------------------VDFLMDII 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   249 SfeeTVPVPGSANGiNALGLVVFSVAFGLVIGGMKHKGRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKI--LEM 326
Cdd:PRK01663 138 P---TTVVGAFASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVNMIMKLAPIGAFGAMAFTIgkYGV 213

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   327 EDMAVLGGQLGMYTLTVIVGLFLHAGGVLPLIYFlvthrNPFPFIGGMLQALITAMGTSSSSATLPITFRCLEEgLGVDR 406
Cdd:PRK01663 214 GSLVQLGQLIGCFYITCILFVFVVLGAIARLTGF-----SIFKFIRYIKEELLIVLGTSSSESALPRMMEKMEK-LGCKK 287

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   407 RITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISITATAASVGAAGIPQAGLVTMVIVLTSVG-LPTE 485
Cdd:PRK01663 288 SVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIPVA 367

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
gi 6678003   486 DITLIIAVDWFLDRLRTMTNVLGDSIGAAVIehlSQRELELQEAELT 532
Cdd:PRK01663 368 GLALILGIDRFMSEARALTNLIGNGVATVVV---AKWEKELDREKLD 411
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
 61-516 3.88e-19

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 90.27  E-value: 3.88e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   61 SAVIIGVSLAFALrpyQLSY--------RQIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASLDN-KATGRMGMRAAVY 131
Cdd:COG1823  36 TGLGLGILFGLIL---QLIYgagspvikQSIDWFNIVGNGYVRLLQMIVMPLVFVSILSAITKLKNaSSLGKISGLIIGI 112

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  132 YMVTTVIAVFIGILMVTIIhpgkgskeGLhregrietvpTADAFMDLVRNmfppnlveacfkqfktqystrvvtrtivrT 211
Cdd:COG1823 113 LLGTTAIAALVGILVALLF--------GL----------TAEGLTQGAAE-----------------------------T 145

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  212 DNGSELgasmsptssvENETSILENVTRAlgtlQEVISFEETVP---VPGsANGINALGLVVFSVAFGLVIGGMKHK--- 285
Cdd:COG1823 146 ARGEAL----------EERLGEVEDLSLP----QQILSFIPTNPfadLTG-ARPTSTIAVVIFAAFLGIAALGLRRKkpe 210

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  286 -GRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAgKIL---EMEDMAVLGG-----QLGMYTLTVIVGLFLHAGGVLP 356
Cdd:COG1823 211 qAETFLKGIDALQAIVMRLVRLVLRLTPYGVLALMT-KVVatsDFADILNLGKfvvasYVALIIMFIVHLLLLALAGLNP 289

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  357 LIYFlvthRNPFPfiggmlqALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTA-LYEALAAIFI 435
Cdd:COG1823 290 LTYF----KKVWP-------VLTFAFTSRSSAGTIPLNIETQTKRLGVPEGIANFAASFGATIGQNGCAgIYPAMLAVMI 358

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  436 A-QVNNYELNLGQITTISITATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVlGDSIGAA 514
Cdd:COG1823 359 ApTVGINPLDPSFILTLIAVVTISSFGVAGVGGGATFAALIVLSAMGLPVALAGLLISIEPLIDMGRTALNV-SGSMTAG 437


                ..
gi 6678003  515 VI 516
Cdd:COG1823 438 TV 439
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 260-465 1.04e-16

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 82.22  E-value: 1.04e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   260 ANGINAL------GLVVFSVAFGLvigGMKHKGRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLG 333
Cdd:PRK13628 136 DNPINALlnanyiGILAWAIGLGL---ALRHASDTTKNVVNDLSEAVSQIVKWVIRFAPIGIFGLVASTLAETGFSALAG 212

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   334 -GQLgmytLTVIVG-LFLHAGGVLPLIYFLVTHRNPFPFIggmLQAL----ITAMGTSSSSATLPITFRcLEEGLGVDRR 407
Cdd:PRK13628 213 yAQL----LAVLVGcMLFVALVVNPLIVFWKIRRNPYPLV---FTCLresgVTAFFTRSSAANIPVNMA-LCEKLGLDED 284

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6678003   408 ITRFVLPVGATVNMDGtalyealAAIFI-----AQVN--NYELNLGQITTISITATAASVGAAGI 465
Cdd:PRK13628 285 TYSVSIPLGATINMAG-------AAITItvltlAAVHtlGIPVDLPTALLLSVVAAISACGASGV 342
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
260-466 1.46e-16

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 81.76  E-value: 1.46e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  260 ANGINAL------GLVVFSVAFGLvigGMKHKGRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLG 333
Cdd:COG3633 135 DNPVNALananyiGILAWAIGLGL---ALRHASDTTKTVLSDLSDAVSKIVRWVIRFAPLGIFGLVASTVATTGFSALLG 211

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003  334 -GQLgmytLTVIVG-LFLHAGGVLPLIYFLVTHRNPFPFIggmLQAL----ITAMGTSSSSATLPITFRcLEEGLGVDRR 407
Cdd:COG3633 212 yAHL----LAVLVGcMLFVALVVNPLIVFLKIRRNPYPLV---FTCLresgITAFFTRSSAANIPVNMA-LCEKLGLDED 283

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6678003  408 ITRFVLPVGATVNMDGtalyealAAIFI-----AQVN--NYELNLGQITTISITATAASVGAAGIP 466
Cdd:COG3633 284 TYSVSIPLGATINMAG-------AAITItvltlAAVHtlGIEVDLPTALLLSVVAAVSACGASGVA 342
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
 264-523 5.61e-12

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 67.00  E-value: 5.61e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   264 NALGLVVFSVAFGLvigGMKHKGRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVlgGQLGMYTLTV 343
Cdd:PRK14695  60 NYIGILSWAVIFGI---AMREASKNSKELLKTIADVTSKIVEWIINLAPFGILGLVFKTISDKGVGSL--ANYGILLVLL 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   344 IVGLFLHAGGVLPLIYFLVTHRNPFPFIGGMLQ-ALITAMGTSSSSATLPITFRcLEEGLGVDRRITRFVLPVGATVNMD 422
Cdd:PRK14695 135 VTTMLFVAPVVNPLIAFFFMRRNPYPLVWNCLRvSGVTAFFTRSSATNIPVNMK-LCHDLGLNPDTYSVSIPLGSTINMA 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678003   423 GTALYEALAAIFIAQVNNYELNLGQITTISITATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFL----D 498
Cdd:PRK14695 214 GVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIgviqD 293

                        250       260
                 ....*....|....*....|....*
gi 6678003   499 RLRTMTNVLGDSIGAAVIEHLSQRE 523
Cdd:PRK14695 294 SCETALNSSTDVLFTAVAEYAATRK 318
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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