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Conserved domains on  [gi|5803086|ref|NP_006841|]
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interleukin-24 isoform 1 precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
IL10 super family cl02501
Interleukin 10;
73-200 4.20e-12

Interleukin 10;


The actual alignment was detected with superfamily member PHA02839:

Pssm-ID: 413341  Cd Length: 156  Bit Score: 61.54  E-value: 4.20e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5803086    73 FWAVKDTMQAQDNITSARLLQQEVLQNVSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQ 152
Cdd:PHA02839  35 FFKVRNVVQADDVDHNLRILTPALLNNITVSETCFFIYDMFELYLNDVFVKYTNTALKLNILKSLSSVANNFLAIFNKVK 114
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 5803086   153 PSQENEMfSIRDSAHRRFLLFRRAFKQLdveaaltkaLGEVDILLTWM 200
Cdd:PHA02839 115 KRRVKKN-NVNVLEIKKLLLIDNNCKKL---------FSEIDIFLTWV 152
 
Name Accession Description Interval E-value
PHA02839 PHA02839
Il-24-like protein; Provisional
73-200 4.20e-12

Il-24-like protein; Provisional


Pssm-ID: 165182  Cd Length: 156  Bit Score: 61.54  E-value: 4.20e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5803086    73 FWAVKDTMQAQDNITSARLLQQEVLQNVSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQ 152
Cdd:PHA02839  35 FFKVRNVVQADDVDHNLRILTPALLNNITVSETCFFIYDMFELYLNDVFVKYTNTALKLNILKSLSSVANNFLAIFNKVK 114
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 5803086   153 PSQENEMfSIRDSAHRRFLLFRRAFKQLdveaaltkaLGEVDILLTWM 200
Cdd:PHA02839 115 KRRVKKN-NVNVLEIKKLLLIDNNCKKL---------FSEIDIFLTWV 152
IL10 pfam00726
Interleukin 10;
67-203 9.22e-03

Interleukin 10;


Pssm-ID: 334228  Cd Length: 170  Bit Score: 35.74  E-value: 9.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5803086     67 QKLWEAFWAVKDTMQAQDNITSArLLQQEVLQNVSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRtlKSFSTLANNFVL 146
Cdd:pfam00726  38 RELRDAFSRVKTFFQTKDQLDNL-LLTESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENHGPEIK--EHVNSLGEKLKT 114
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 5803086    147 IVSQLQPSQEnemFSIRDSAHRRFLLFRRAFKQLDvEAALTKALGEVDILLTWMQKF 203
Cdd:pfam00726 115 LRLRLRRCHR---FLPCENKSKAVEKVKNAFNKLQ-EKGVYKAMSEFDIFINYIETY 167
 
Name Accession Description Interval E-value
PHA02839 PHA02839
Il-24-like protein; Provisional
73-200 4.20e-12

Il-24-like protein; Provisional


Pssm-ID: 165182  Cd Length: 156  Bit Score: 61.54  E-value: 4.20e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5803086    73 FWAVKDTMQAQDNITSARLLQQEVLQNVSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQ 152
Cdd:PHA02839  35 FFKVRNVVQADDVDHNLRILTPALLNNITVSETCFFIYDMFELYLNDVFVKYTNTALKLNILKSLSSVANNFLAIFNKVK 114
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 5803086   153 PSQENEMfSIRDSAHRRFLLFRRAFKQLdveaaltkaLGEVDILLTWM 200
Cdd:PHA02839 115 KRRVKKN-NVNVLEIKKLLLIDNNCKKL---------FSEIDIFLTWV 152
IL10 pfam00726
Interleukin 10;
67-203 9.22e-03

Interleukin 10;


Pssm-ID: 334228  Cd Length: 170  Bit Score: 35.74  E-value: 9.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5803086     67 QKLWEAFWAVKDTMQAQDNITSArLLQQEVLQNVSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRtlKSFSTLANNFVL 146
Cdd:pfam00726  38 RELRDAFSRVKTFFQTKDQLDNL-LLTESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENHGPEIK--EHVNSLGEKLKT 114
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 5803086    147 IVSQLQPSQEnemFSIRDSAHRRFLLFRRAFKQLDvEAALTKALGEVDILLTWMQKF 203
Cdd:pfam00726 115 LRLRLRRCHR---FLPCENKSKAVEKVKNAFNKLQ-EKGVYKAMSEFDIFINYIETY 167
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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