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Conserved domains on  [gi|1519313909|ref|NP_006415|]
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sodium-dependent phosphate transport protein 2B isoform a [Homo sapiens]

Protein Classification

sodium-dependent phosphate transport protein 2( domain architecture ID 11490082)

sodium-dependent phosphate transport protein 2 may be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
2a58 TIGR01013
Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron ...
105-604 1.10e-169

Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron carrying compounds]


:

Pssm-ID: 162157 [Multi-domain]  Cd Length: 456  Bit Score: 493.61  E-value: 1.10e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 105 LGFLYFFVCSLDILSSAFQLVGGKMAGQFFSNSSIMSNPLLGLVIGVLVTVLVQSSSTSTSIVVSMVSSSLLTVRAAIPI 184
Cdd:TIGR01013   1 LVLLFVFVCSLAVLSAAFILLGAKVGGAIFADILITDNPWASPLLGFLGTVLLQSSSTSRSIVVGMVSAGLLLVLLAIPL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 185 IMGANIGTSITNTIVALMQVGDRSEFRRAFAGATVHDFFNWLSVLVLLPVEVATHYLEIITQLIVESFHFKNGEDAPDLL 264
Cdd:TIGR01013  81 IMGANIGSSVTNAIVAIMQSGDRAWFRRAFIGATVADIFNSSLALVLLPLELTTGGIESVTLLVVLVFGANGGGDAPDLL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 265 KVITKPFTKLIVQLDKKVISQIAmndeKAKNKSLVKIWCKTFTnktqinvtvpstanctspSLCWTDGiqnwtmknvtyk 344
Cdd:TIGR01013 161 NSLTAPATALIVQLDNLIIRLIG----SLLILPLIDILASTLS------------------SLPVPES------------ 206
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 345 eNIAKCQHIFVNfhlpdlaVGTILLILSLLVLCGCLIMIVKILGSVLKGQVATVIKKTINTDFPFPFAWLTGYLAILVGA 424
Cdd:TIGR01013 207 -NLPIEAHIFVN-------VGLILLALPFVRLCARLILVVIPLNSLLDGQVAPVILDVINLDTPVPFLWVTGYEALLVGD 278
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 425 GMTFIVQSSSVFTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAALASPGNALRSSLQIALCHFFFNISGILLWYP 504
Cdd:TIGR01013 279 AMTFIIQSSSVFTSALTPLVGKGVISLERAYPLVLGSNIGTTLTAVLAALLSEDEKRRSALQIAYCHNLFNISGIVLFYP 358
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 505 IPFTRLPIRMAKGLGNISAKYRWFAVFYLIIFFFLIPLTVFGLSLAGWRVLVGVGVPVVFIIILVLCLRLLQSRCPRvlP 584
Cdd:TIGR01013 359 LPCTRKPIAAARGFGDDGSKYRWFLIVYLVLNFLLAPSLLFGLDLNLARRLVGVKIPFRILELFSSLLHVLQLRCPR--P 436
                         490       500
                  ....*....|....*....|
gi 1519313909 585 KKLQNWNFLPLWMRSLKPWD 604
Cdd:TIGR01013 437 QSLQTWSFLPDWLRSLKRLD 456
 
Name Accession Description Interval E-value
2a58 TIGR01013
Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron ...
105-604 1.10e-169

Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 162157 [Multi-domain]  Cd Length: 456  Bit Score: 493.61  E-value: 1.10e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 105 LGFLYFFVCSLDILSSAFQLVGGKMAGQFFSNSSIMSNPLLGLVIGVLVTVLVQSSSTSTSIVVSMVSSSLLTVRAAIPI 184
Cdd:TIGR01013   1 LVLLFVFVCSLAVLSAAFILLGAKVGGAIFADILITDNPWASPLLGFLGTVLLQSSSTSRSIVVGMVSAGLLLVLLAIPL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 185 IMGANIGTSITNTIVALMQVGDRSEFRRAFAGATVHDFFNWLSVLVLLPVEVATHYLEIITQLIVESFHFKNGEDAPDLL 264
Cdd:TIGR01013  81 IMGANIGSSVTNAIVAIMQSGDRAWFRRAFIGATVADIFNSSLALVLLPLELTTGGIESVTLLVVLVFGANGGGDAPDLL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 265 KVITKPFTKLIVQLDKKVISQIAmndeKAKNKSLVKIWCKTFTnktqinvtvpstanctspSLCWTDGiqnwtmknvtyk 344
Cdd:TIGR01013 161 NSLTAPATALIVQLDNLIIRLIG----SLLILPLIDILASTLS------------------SLPVPES------------ 206
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 345 eNIAKCQHIFVNfhlpdlaVGTILLILSLLVLCGCLIMIVKILGSVLKGQVATVIKKTINTDFPFPFAWLTGYLAILVGA 424
Cdd:TIGR01013 207 -NLPIEAHIFVN-------VGLILLALPFVRLCARLILVVIPLNSLLDGQVAPVILDVINLDTPVPFLWVTGYEALLVGD 278
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 425 GMTFIVQSSSVFTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAALASPGNALRSSLQIALCHFFFNISGILLWYP 504
Cdd:TIGR01013 279 AMTFIIQSSSVFTSALTPLVGKGVISLERAYPLVLGSNIGTTLTAVLAALLSEDEKRRSALQIAYCHNLFNISGIVLFYP 358
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 505 IPFTRLPIRMAKGLGNISAKYRWFAVFYLIIFFFLIPLTVFGLSLAGWRVLVGVGVPVVFIIILVLCLRLLQSRCPRvlP 584
Cdd:TIGR01013 359 LPCTRKPIAAARGFGDDGSKYRWFLIVYLVLNFLLAPSLLFGLDLNLARRLVGVKIPFRILELFSSLLHVLQLRCPR--P 436
                         490       500
                  ....*....|....*....|
gi 1519313909 585 KKLQNWNFLPLWMRSLKPWD 604
Cdd:TIGR01013 437 QSLQTWSFLPDWLRSLKRLD 456
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
418-510 3.65e-20

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 94.48  E-value: 3.65e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 418 LAILVGAGMTFIVQSSSVFTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAALASPGNALRsslqIALCHFFFNIS 497
Cdd:COG1283   176 LGVLVGALLTALVQSSSATVGLLLALAAQGLIPLEAALALVLGANIGTTITALLASIGANVAARR----AALAHLLFNLI 251
                          90
                  ....*....|....*
gi 1519313909 498 GILLWYPI--PFTRL 510
Cdd:COG1283   252 GVLIFLPLlpPFAAL 266
Na_Pi_cotrans pfam02690
Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters ...
417-474 1.24e-11

Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows re-absorption of filtered Pi in the proximal tubule.


Pssm-ID: 460653 [Multi-domain]  Cd Length: 137  Bit Score: 62.42  E-value: 1.24e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1519313909 417 YLAILVGAGMTFIVQSSSVFTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAAL 474
Cdd:pfam02690  33 LKGFLVGLLVTALLQSSSATTVMVVGFVNAGLLTLAQALGVIMGANIGTTVTAQLIAF 90
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
405-505 1.81e-10

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 62.62  E-value: 1.81e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 405 TDFPFPFAWLT-----GYLAILVGAGMTFIVQSSSVFTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAALASPgn 479
Cdd:NF037997  148 TSLPFVHSLLEstnesLLLALLIGTVLTAIIQSSSATTGITMSFLNEGILTLPAGIAIMLGANIGTCITALLASIGSG-- 225
                          90       100
                  ....*....|....*....|....*.
gi 1519313909 480 alRSSLQIALCHFFFNISGILLWYPI 505
Cdd:NF037997  226 --KEAKLTAYAHIWLNVLGVLLFLPF 249
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
92-233 2.48e-06

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 49.91  E-value: 2.48e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909  92 LCFFQGIGRLI----LLLGFLYFFVCSldilsSAFQLVGGKMAGQFFSNSSIMS---NPLLGLVIGVLVTVLVQSSSTST 164
Cdd:NF037997  111 LLLFLPRPALKslgmSLFGLGAIFTAM-----RGFESLAGPLTSLPFVHSLLEStneSLLLALLIGTVLTAIIQSSSATT 185
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 165 SIVVSMVSSSLLTVRAAIPIIMGANIGTSITNTIVAlmqVGDRSEFRR-AFAgatvHDFFNWLSVLVLLP 233
Cdd:NF037997  186 GITMSFLNEGILTLPAGIAIMLGANIGTCITALLAS---IGSGKEAKLtAYA----HIWLNVLGVLLFLP 248
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
122-201 8.86e-04

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 41.82  E-value: 8.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 122 FQLVGGKMAGQFfsnSSIMSNPLLGLVIGVLVTVLVQSSSTSTSIVVSMVSSSLLTVRAAIPIIMGANIGTSITNTIVAL 201
Cdd:NF037997   20 FNLSGHKLKTWL---LKFTDTPLKGFLTGTVITAILQSSSAVMVLTVGLVSAGILTFRQSIGIILGTNIGTTFTTEFITF 96
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
419-474 5.24e-03

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 39.51  E-value: 5.24e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1519313909 419 AILVGAGMTFIVQSSSVFTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAAL 474
Cdd:NF037997   41 GFLTGTVITAILQSSSAVMVLTVGLVSAGILTFRQSIGIILGTNIGTTFTTEFITF 96
 
Name Accession Description Interval E-value
2a58 TIGR01013
Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron ...
105-604 1.10e-169

Phosphate:Na+ Symporter (PNaS) Family; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 162157 [Multi-domain]  Cd Length: 456  Bit Score: 493.61  E-value: 1.10e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 105 LGFLYFFVCSLDILSSAFQLVGGKMAGQFFSNSSIMSNPLLGLVIGVLVTVLVQSSSTSTSIVVSMVSSSLLTVRAAIPI 184
Cdd:TIGR01013   1 LVLLFVFVCSLAVLSAAFILLGAKVGGAIFADILITDNPWASPLLGFLGTVLLQSSSTSRSIVVGMVSAGLLLVLLAIPL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 185 IMGANIGTSITNTIVALMQVGDRSEFRRAFAGATVHDFFNWLSVLVLLPVEVATHYLEIITQLIVESFHFKNGEDAPDLL 264
Cdd:TIGR01013  81 IMGANIGSSVTNAIVAIMQSGDRAWFRRAFIGATVADIFNSSLALVLLPLELTTGGIESVTLLVVLVFGANGGGDAPDLL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 265 KVITKPFTKLIVQLDKKVISQIAmndeKAKNKSLVKIWCKTFTnktqinvtvpstanctspSLCWTDGiqnwtmknvtyk 344
Cdd:TIGR01013 161 NSLTAPATALIVQLDNLIIRLIG----SLLILPLIDILASTLS------------------SLPVPES------------ 206
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 345 eNIAKCQHIFVNfhlpdlaVGTILLILSLLVLCGCLIMIVKILGSVLKGQVATVIKKTINTDFPFPFAWLTGYLAILVGA 424
Cdd:TIGR01013 207 -NLPIEAHIFVN-------VGLILLALPFVRLCARLILVVIPLNSLLDGQVAPVILDVINLDTPVPFLWVTGYEALLVGD 278
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 425 GMTFIVQSSSVFTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAALASPGNALRSSLQIALCHFFFNISGILLWYP 504
Cdd:TIGR01013 279 AMTFIIQSSSVFTSALTPLVGKGVISLERAYPLVLGSNIGTTLTAVLAALLSEDEKRRSALQIAYCHNLFNISGIVLFYP 358
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 505 IPFTRLPIRMAKGLGNISAKYRWFAVFYLIIFFFLIPLTVFGLSLAGWRVLVGVGVPVVFIIILVLCLRLLQSRCPRvlP 584
Cdd:TIGR01013 359 LPCTRKPIAAARGFGDDGSKYRWFLIVYLVLNFLLAPSLLFGLDLNLARRLVGVKIPFRILELFSSLLHVLQLRCPR--P 436
                         490       500
                  ....*....|....*....|
gi 1519313909 585 KKLQNWNFLPLWMRSLKPWD 604
Cdd:TIGR01013 437 QSLQTWSFLPDWLRSLKRLD 456
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
418-510 3.65e-20

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 94.48  E-value: 3.65e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 418 LAILVGAGMTFIVQSSSVFTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAALASPGNALRsslqIALCHFFFNIS 497
Cdd:COG1283   176 LGVLVGALLTALVQSSSATVGLLLALAAQGLIPLEAALALVLGANIGTTITALLASIGANVAARR----AALAHLLFNLI 251
                          90
                  ....*....|....*
gi 1519313909 498 GILLWYPI--PFTRL 510
Cdd:COG1283   252 GVLIFLPLlpPFAAL 266
Na_Pi_cotrans pfam02690
Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters ...
417-474 1.24e-11

Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows re-absorption of filtered Pi in the proximal tubule.


Pssm-ID: 460653 [Multi-domain]  Cd Length: 137  Bit Score: 62.42  E-value: 1.24e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1519313909 417 YLAILVGAGMTFIVQSSSVFTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAAL 474
Cdd:pfam02690  33 LKGFLVGLLVTALLQSSSATTVMVVGFVNAGLLTLAQALGVIMGANIGTTVTAQLIAF 90
Na_Pi_cotrans pfam02690
Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters ...
110-201 1.88e-11

Na+/Pi-cotransporter; This is a family of mainly mammalian type II renal Na+/Pi-cotransporters with other related sequences from lower eukaryotes and bacteria some of which are also Na+/Pi-cotransporters. In the kidney the type II renal Na+/Pi-cotransporters protein allows re-absorption of filtered Pi in the proximal tubule.


Pssm-ID: 460653 [Multi-domain]  Cd Length: 137  Bit Score: 62.03  E-value: 1.88e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 110 FFVCSLDILSSAFQLVGGKMAGQFFSnsSIMSNPLLGLVIGVLVTVLVQSSSTSTSIVVSMVSSSLLTVRAAIPIIMGAN 189
Cdd:pfam02690   1 LFLFGMKLMSDGLQKLAGGRLRRILE--KLTSNPLKGFLVGLLVTALLQSSSATTVMVVGFVNAGLLTLAQALGVIMGAN 78
                          90
                  ....*....|..
gi 1519313909 190 IGTSITNTIVAL 201
Cdd:pfam02690  79 IGTTVTAQLIAF 90
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
405-505 1.81e-10

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 62.62  E-value: 1.81e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 405 TDFPFPFAWLT-----GYLAILVGAGMTFIVQSSSVFTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAALASPgn 479
Cdd:NF037997  148 TSLPFVHSLLEstnesLLLALLIGTVLTAIIQSSSATTGITMSFLNEGILTLPAGIAIMLGANIGTCITALLASIGSG-- 225
                          90       100
                  ....*....|....*....|....*.
gi 1519313909 480 alRSSLQIALCHFFFNISGILLWYPI 505
Cdd:NF037997  226 --KEAKLTAYAHIWLNVLGVLLFLPF 249
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
96-234 2.68e-10

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 63.27  E-value: 2.68e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909  96 QGIGRLILLLGFLyFFvcSLDILSSAFQ-LVGGKMAGQFFSnsSIMSNPLLGLVIGVLVTVLVQSSSTSTSIVVSMVSSS 174
Cdd:COG1283   131 RQIGRILIGFGLL-FL--GLDLMSEAMEpLRDSPAFRALLA--SLSGNPLLGVLVGALLTALVQSSSATVGLLLALAAQG 205
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 175 LLTVRAAIPIIMGANIGTSITNTIVALmqvGDRSEFRRAfagATVHDFFNWLSVLVLLPV 234
Cdd:COG1283   206 LIPLEAALALVLGANIGTTITALLASI---GANVAARRA---ALAHLLFNLIGVLIFLPL 259
NptA COG1283
Na+/phosphate symporter [Inorganic ion transport and metabolism];
418-474 1.58e-07

Na+/phosphate symporter [Inorganic ion transport and metabolism];


Pssm-ID: 440894 [Multi-domain]  Cd Length: 540  Bit Score: 54.42  E-value: 1.58e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1519313909 418 LAILVGAGMTFIVQSSSVFTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAAL 474
Cdd:COG1283    49 KGVLAGALVTALLQSSSATTVMVVGFVNAGLMTLAQALGVILGANIGTTLTAQLIAF 105
NaPi_cotrn_rel TIGR00704
Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized ...
379-543 7.34e-07

Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized protein from Bacillus subtilis and correponding lengths of longer proteins from E. coli and Treponema pallidum. PSI-BLAST analysis converges to demonstrate homology to one other group of proteins, type II sodium/phosphate (Na/Pi) cotransporters. A well-conserved repeated domain in this family, approximately 60 residues in length, is also repeated in the Na/Pi cotransporters, although with greater spacing between the repeats. The two families share additional homology in the region after the first repeat, share the properly of having extensive hydrophobic regions, and may be similar in function. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273225 [Multi-domain]  Cd Length: 308  Bit Score: 51.46  E-value: 7.34e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 379 CLIMIVKILGSVLKGQVATVIKKTINTDFpfpfawltgYLAILVGAGMTFIVQSSSVFTSALTPLIGIGVITIERAYPLT 458
Cdd:TIGR00704 143 AIEGFSHAAGPITKAKGGADIFAHLNDDI---------LLAALIGAMFAAIIHSSLAAIGILASFMAAGIIGFPQALCLV 213
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 459 LGSNIGTTTTAILAALAspGNAlrSSLQIALCHFFFNISGILLWYPIpFTRLPIRMAKGLGNISAKYRWFAVFY-LIIFF 537
Cdd:TIGR00704 214 IGANIGSCILAMLAASA--AGA--AAKQTALAHLLFKLLGSAIILPF-LHAAAEFMEKLSLDKAEKIAHFHLFFnLVRAL 288

                  ....*.
gi 1519313909 538 FLIPLT 543
Cdd:TIGR00704 289 LFLPFT 294
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
92-233 2.48e-06

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 49.91  E-value: 2.48e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909  92 LCFFQGIGRLI----LLLGFLYFFVCSldilsSAFQLVGGKMAGQFFSNSSIMS---NPLLGLVIGVLVTVLVQSSSTST 164
Cdd:NF037997  111 LLLFLPRPALKslgmSLFGLGAIFTAM-----RGFESLAGPLTSLPFVHSLLEStneSLLLALLIGTVLTAIIQSSSATT 185
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 165 SIVVSMVSSSLLTVRAAIPIIMGANIGTSITNTIVAlmqVGDRSEFRR-AFAgatvHDFFNWLSVLVLLP 233
Cdd:NF037997  186 GITMSFLNEGILTLPAGIAIMLGANIGTCITALLAS---IGSGKEAKLtAYA----HIWLNVLGVLLFLP 248
NaPi_cotrn_rel TIGR00704
Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized ...
418-469 5.47e-04

Na/Pi-cotransporter; This model describes essentially the full length of an uncharacterized protein from Bacillus subtilis and correponding lengths of longer proteins from E. coli and Treponema pallidum. PSI-BLAST analysis converges to demonstrate homology to one other group of proteins, type II sodium/phosphate (Na/Pi) cotransporters. A well-conserved repeated domain in this family, approximately 60 residues in length, is also repeated in the Na/Pi cotransporters, although with greater spacing between the repeats. The two families share additional homology in the region after the first repeat, share the properly of having extensive hydrophobic regions, and may be similar in function. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273225 [Multi-domain]  Cd Length: 308  Bit Score: 42.60  E-value: 5.47e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1519313909 418 LAILVGAGMTFIVQSSSVFTSALTPLIGIGVITIERAYPLTLGSNIGTTTTA 469
Cdd:TIGR00704  46 KAFCAGIGFTAILQSSNAFMMIVIGFVAADLLAFAPAIPIILGADVGSAFMA 97
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
122-201 8.86e-04

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 41.82  E-value: 8.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1519313909 122 FQLVGGKMAGQFfsnSSIMSNPLLGLVIGVLVTVLVQSSSTSTSIVVSMVSSSLLTVRAAIPIIMGANIGTSITNTIVAL 201
Cdd:NF037997   20 FNLSGHKLKTWL---LKFTDTPLKGFLTGTVITAILQSSSAVMVLTVGLVSAGILTFRQSIGIILGTNIGTTFTTEFITF 96
Na_Pi_symport NF037997
Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) ...
419-474 5.24e-03

Na/Pi symporter; Proteins of this family belong to the Phosphate:Na+ Symporter (PNaS) superfamily.


Pssm-ID: 411591 [Multi-domain]  Cd Length: 294  Bit Score: 39.51  E-value: 5.24e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1519313909 419 AILVGAGMTFIVQSSSVFTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAAL 474
Cdd:NF037997   41 GFLTGTVITAILQSSSAVMVLTVGLVSAGILTFRQSIGIILGTNIGTTFTTEFITF 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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