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Concise Results
Standard Results
Full Results
janus kinase and microtubule-interacting protein 3 isoform p [Homo sapiens]
Protein Classification
SMC_prok_B and JAKMIP_CC3 domain-containing protein ( domain architecture ID 13531091 )
SMC_prok_B and JAKMIP_CC3 domain-containing protein
List of domain hits
Name
Accession
Description
Interval
E-value
JAKMIP_CC3
pfam16034 JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP ...
355-551
3.13e-85
JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP family (Janus kinase and microtubule-interacting proteins) and is predicted to be a coiled coil. It interacts with the Janus family kinases Tyk2 and Jak1.
Pssm-ID: 464986 [Multi-domain]
Cd Length: 199
Bit Score: 268.29
E-value: 3.13e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 355 ERDKL L R F RKQR K K MA K LPKP - V VVETFFGYDEEAS LE S DG SS V SY Q TDRTD Q TP C TPD D DL E EG M A K EE T ELRFRQLT M 433
Cdd:pfam16034 1 ERDKL I R A RKQR R K EK K KKLR d M VVETFFGYDEEAS VD S ET SS L SY N TDRTD S TP A TPD E DL D EG V A A EE A ELRFRQLT R 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 434 EYQALQRAYALLQEQ V GGTLDAERE V KTREQLQAE VQ RAQ A RIEDLE K ALA EQ GQD M KW I EEKQAL Y RRNQELVEKI KQ M 513
Cdd:pfam16034 81 EYQALQRAYALLQEQ S GGTLDAERE A KTREQLQAE LR RAQ S RIEDLE S ALA QK GQD S KW V EEKQAL I RRNQELVEKI RI M 160
170 180 190
....*....|....*....|....*....|....*...
gi 1972712332 514 E T EE A RL RH E V QDARDQNELLEFRILELEERER K SPAI 551
Cdd:pfam16034 161 E Q EE G RL KN E I QDARDQNELLEFRILELEERER R SPAI 198
Smc super family
cl34174 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
26-545
1.59e-10
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
COG1196 :Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 64.96
E-value: 1.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 26 ED L R A K L TDIQIELQQEKSKVSKV E R E KNQELRQVR E H E QHKTAVL L T EL KTK L H E EK m K EL QAVRET l LRQHE AEL L R V 105
Cdd:COG1196 223 KE L E A E L LLLKLRELEAELEELEA E L E ELEAELEEL E A E LAELEAE L E EL RLE L E E LE - L EL EEAQAE - EYELL AEL A R L 300
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 106 IKIKDNENQ R LQA L LSA L RDGGP E KVKTVLLS E AK EE AKKGF E V E KVKMQQ E IS E LKGAKRQV EEAL tlvi QADKIKA AE 185
Cdd:COG1196 301 EQDIARLEE R RRE L EER L EELEE E LAELEEEL E EL EE ELEEL E E E LEEAEE E LE E AEAELAEA EEAL ---- LEAEAEL AE 376
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 186 IRSVYHLHQ EE ITRIKKECEREIRR L QLD E KDARRFQLKIAE L SAIIRK LE DRN A L L S EE RN E LLKRVR EA ESQYKP L LD 265
Cdd:COG1196 377 AEEELEELA EE LLEALRAAAELAAQ L EEL E EAEEALLERLER L EEELEE LE EAL A E L E EE EE E EEEALE EA AEEEAE L EE 456
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 266 KNKR L SRKNED L SHALRRM E NK L KFVTQ E NI E MRQ R A giirrp SS L NDLDQSQDEREVDFLKLQIVEQQNLI -------- 337
Cdd:COG1196 457 EEEA L LELLAE L LEEAALL E AA L AELLE E LA E AAA R L ------ LL L LEAEADYEGFLEGVKAALLLAGLRGL agavavli 530
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 338 --- DELSKT LE T A ------- GY V KSVLERDKLLRFR K QR K -- KMAK LP KPVVVETFFGYDEE A SLESDGSSVSYQT D RTD 405
Cdd:COG1196 531 gve AAYEAA LE A A laaalqn IV V EDDEVAAAAIEYL K AA K ag RATF LP LDKIRARAALAAAL A RGAIGAAVDLVAS D LRE 610
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 406 QTPCTPDDDLEEGMAKEETELRFRQ L TMEYQALQ R AYALLQ E QV GG TLDAEREVKT R EQ L Q A EVQR A Q A RI E D L EKA LAE 485
Cdd:COG1196 611 ADARYYVLGDTLLGRTLVAARLEAA L RRAVTLAG R LREVTL E GE GG SAGGSLTGGS R RE L L A ALLE A E A EL E E L AER LAE 690
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 486 Q gqdmkw IE E KQALYRRNQ E LVEKIKQM E T E EARLRH E VQDARD Q N E LLEFRI LE LEER E 545
Cdd:COG1196 691 E ------ EL E LEEALLAEE E EERELAEA E E E RLEEEL E EEALEE Q L E AEREEL LE ELLE E 744
SMC_prok_B super family
cl37069 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
421-745
2.67e-03
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
TIGR02168 :Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 41.20
E-value: 2.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 421 K E ET EL RFRQ L TMEYQA L QRAYAL LQE QV ggtlda EREVKTR E Q L Q AE V Q RAQARI E D L EKALA E QG qdmkwi EE KQA L Y 500
Cdd:TIGR02168 220 A E LR EL ELAL L VLRLEE L REELEE LQE EL ------ KEAEEEL E E L T AE L Q ELEEKL E E L RLEVS E LE ------ EE IEE L Q 287
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 501 RRNQE L VEK I KQM E TEEAR LR HEVQDARD Q N E L LE FRIL ELE ERERKSPAIS fhh TPFVDGKSP L QVYC E AE gvtdiv V A 580
Cdd:TIGR02168 288 KELYA L ANE I SRL E QQKQI LR ERLANLER Q L E E LE AQLE ELE SKLDELAEEL --- AELEEKLEE L KEEL E SL ------ E A 358
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 581 EL MKKLDI L GDNANLTN E EQVVVIQA R TVLTLA E kwl Q QI EETEAALQ R kmvd LE SEK E LFSKQKGY L DE E LDYRKQA L D 660
Cdd:TIGR02168 359 EL EELEAE L EELESRLE E LEEQLETL R SKVAQL E --- L QI ASLNNEIE R ---- LE ARL E RLEDRRER L QQ E IEELLKK L E 431
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 661 Q A NKHI L EL E AMLYDALQQ E AGAKVAE L LSEE E REKLKVAVEQWKRQ vmse LR ER DAQI L RE R MEL L QLA Q QRIKELE E R 740
Cdd:TIGR02168 432 E A ELKE L QA E LEELEEELE E LQEELER L EEAL E ELREELEEAEQALD ---- AA ER ELAQ L QA R LDS L ERL Q ENLEGFS E G 507
....*
gi 1972712332 741 IE A QK 745
Cdd:TIGR02168 508 VK A LL 512
Name
Accession
Description
Interval
E-value
JAKMIP_CC3
pfam16034 JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP ...
355-551
3.13e-85
JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP family (Janus kinase and microtubule-interacting proteins) and is predicted to be a coiled coil. It interacts with the Janus family kinases Tyk2 and Jak1.
Pssm-ID: 464986 [Multi-domain]
Cd Length: 199
Bit Score: 268.29
E-value: 3.13e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 355 ERDKL L R F RKQR K K MA K LPKP - V VVETFFGYDEEAS LE S DG SS V SY Q TDRTD Q TP C TPD D DL E EG M A K EE T ELRFRQLT M 433
Cdd:pfam16034 1 ERDKL I R A RKQR R K EK K KKLR d M VVETFFGYDEEAS VD S ET SS L SY N TDRTD S TP A TPD E DL D EG V A A EE A ELRFRQLT R 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 434 EYQALQRAYALLQEQ V GGTLDAERE V KTREQLQAE VQ RAQ A RIEDLE K ALA EQ GQD M KW I EEKQAL Y RRNQELVEKI KQ M 513
Cdd:pfam16034 81 EYQALQRAYALLQEQ S GGTLDAERE A KTREQLQAE LR RAQ S RIEDLE S ALA QK GQD S KW V EEKQAL I RRNQELVEKI RI M 160
170 180 190
....*....|....*....|....*....|....*...
gi 1972712332 514 E T EE A RL RH E V QDARDQNELLEFRILELEERER K SPAI 551
Cdd:pfam16034 161 E Q EE G RL KN E I QDARDQNELLEFRILELEERER R SPAI 198
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
26-545
1.59e-10
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 64.96
E-value: 1.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 26 ED L R A K L TDIQIELQQEKSKVSKV E R E KNQELRQVR E H E QHKTAVL L T EL KTK L H E EK m K EL QAVRET l LRQHE AEL L R V 105
Cdd:COG1196 223 KE L E A E L LLLKLRELEAELEELEA E L E ELEAELEEL E A E LAELEAE L E EL RLE L E E LE - L EL EEAQAE - EYELL AEL A R L 300
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 106 IKIKDNENQ R LQA L LSA L RDGGP E KVKTVLLS E AK EE AKKGF E V E KVKMQQ E IS E LKGAKRQV EEAL tlvi QADKIKA AE 185
Cdd:COG1196 301 EQDIARLEE R RRE L EER L EELEE E LAELEEEL E EL EE ELEEL E E E LEEAEE E LE E AEAELAEA EEAL ---- LEAEAEL AE 376
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 186 IRSVYHLHQ EE ITRIKKECEREIRR L QLD E KDARRFQLKIAE L SAIIRK LE DRN A L L S EE RN E LLKRVR EA ESQYKP L LD 265
Cdd:COG1196 377 AEEELEELA EE LLEALRAAAELAAQ L EEL E EAEEALLERLER L EEELEE LE EAL A E L E EE EE E EEEALE EA AEEEAE L EE 456
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 266 KNKR L SRKNED L SHALRRM E NK L KFVTQ E NI E MRQ R A giirrp SS L NDLDQSQDEREVDFLKLQIVEQQNLI -------- 337
Cdd:COG1196 457 EEEA L LELLAE L LEEAALL E AA L AELLE E LA E AAA R L ------ LL L LEAEADYEGFLEGVKAALLLAGLRGL agavavli 530
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 338 --- DELSKT LE T A ------- GY V KSVLERDKLLRFR K QR K -- KMAK LP KPVVVETFFGYDEE A SLESDGSSVSYQT D RTD 405
Cdd:COG1196 531 gve AAYEAA LE A A laaalqn IV V EDDEVAAAAIEYL K AA K ag RATF LP LDKIRARAALAAAL A RGAIGAAVDLVAS D LRE 610
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 406 QTPCTPDDDLEEGMAKEETELRFRQ L TMEYQALQ R AYALLQ E QV GG TLDAEREVKT R EQ L Q A EVQR A Q A RI E D L EKA LAE 485
Cdd:COG1196 611 ADARYYVLGDTLLGRTLVAARLEAA L RRAVTLAG R LREVTL E GE GG SAGGSLTGGS R RE L L A ALLE A E A EL E E L AER LAE 690
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 486 Q gqdmkw IE E KQALYRRNQ E LVEKIKQM E T E EARLRH E VQDARD Q N E LLEFRI LE LEER E 545
Cdd:COG1196 691 E ------ EL E LEEALLAEE E EERELAEA E E E RLEEEL E EEALEE Q L E AEREEL LE ELLE E 744
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
27-744
1.58e-09
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 61.61
E-value: 1.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 27 D L R A K L TDIQIE L Q -- QEKSKVSKV E REKNQELRQVR E H E QHKTAV ----- L L T EL KTKLH E EKMKELQAVR E TL - L RQH 98
Cdd:TIGR02168 217 E L K A E L RELELA L L vl RLEELREEL E ELQEELKEAEE E L E ELTAEL qelee K L E EL RLEVS E LEEEIEELQK E LY a L ANE 296
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 99 EAE L LRVIK I KDNENQR L QAL L SA L RDGGP E - KV K TVL L S E AKE E AKKGF E VE K VKMQQEIS EL KGAKRQV EE ALTLVIQ 177
Cdd:TIGR02168 297 ISR L EQQKQ I LRERLAN L ERQ L EE L EAQLE E l ES K LDE L A E ELA E LEEKL E EL K EELESLEA EL EELEAEL EE LESRLEE 376
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 178 ADK i KAAEI RS VYHLHQEE I TRIKK E C ER EIR RL Q ------------------- L D E KDARRF Q LKIA EL SAIIRK L EDR 238
Cdd:TIGR02168 377 LEE - QLETL RS KVAQLELQ I ASLNN E I ER LEA RL E rledrrerlqqeieellkk L E E AELKEL Q AELE EL EEELEE L QEE 455
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 239 NAL L S E ERN EL LKRVR EAE SQYKPLLDKNKR L SRKNED L SHALRRM E NKLKF V TQENIEMRQRA GI IRRP S S L NDL D q SQ 318
Cdd:TIGR02168 456 LER L E E ALE EL REELE EAE QALDAAERELAQ L QARLDS L ERLQENL E GFSEG V KALLKNQSGLS GI LGVL S E L ISV D - EG 534
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 319 D E REVD flklq IVEQQN L IDELSKT L ET A GYVKSV L ERDK L L R frkqrkk MAK LP KPVVVE T FFGYDEEAS L ESDGSSVS 398
Cdd:TIGR02168 535 Y E AAIE ----- AALGGR L QAVVVEN L NA A KKAIAF L KQNE L G R ------- VTF LP LDSIKG T EIQGNDREI L KNIEGFLG 602
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 399 YQT D RTDQT P ------------ CTPD DDL EEGMA - KEETELRF R QL T MEYQALQRAYALLQ --- EQVGGT L DAE RE V ktr 462
Cdd:TIGR02168 603 VAK D LVKFD P klrkalsyllgg VLVV DDL DNALE l AKKLRPGY R IV T LDGDLVRPGGVITG gsa KTNSSI L ERR RE I --- 679
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 463 E Q L QAEVQRAQAR I ED LEKALAE --- QGQDMK wi EE KQA L YRRNQ EL VEK I KQMETEE ARL RH EV QDARDQNEL L EFRIL 539
Cdd:TIGR02168 680 E E L EEKIEELEEK I AE LEKALAE lrk ELEELE -- EE LEQ L RKELE EL SRQ I SALRKDL ARL EA EV EQLEERIAQ L SKELT 757
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 540 ELE ERERKS paisfhhtpfvdg KSP L QVYC E AEGVTDIVVA EL MKKLDI L GDNANLTN E EQV vvi QA R TV LTL AEKWLQQ 619
Cdd:TIGR02168 758 ELE AEIEEL ------------- EER L EEAE E ELAEAEAEIE EL EAQIEQ L KEELKALR E ALD --- EL R AE LTL LNEEAAN 821
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 620 IE E TEAA L Q R KMVDL E SEK E LFSK Q KGY L D E ELDYRKQALDQANKH I L ELE AM L YDA L QQE A GAKV A EL L SEE E R E K L KV 699
Cdd:TIGR02168 822 LR E RLES L E R RIAAT E RRL E DLEE Q IEE L S E DIESLAAEIEELEEL I E ELE SE L EAL L NER A SLEE A LA L LRS E L E E L SE 901
730 740 750 760
....*....|....*....|....*....|....*....|....*
gi 1972712332 700 AVEQWKRQVMSEL RE RDA qi LRE RMEL L Q L AQQRIKELEERIEAQ 744
Cdd:TIGR02168 902 ELRELESKRSELR RE LEE -- LRE KLAQ L E L RLEGLEVRIDNLQER 944
COG4913
COG4913 Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
422-546
2.61e-03
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain]
Cd Length: 1089
Bit Score: 41.44
E-value: 2.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 422 E E T E LRFRQLTMEYQ AL QRAYAL LQE Q vggt LD A EREVKTREQLQAE V QR A QAR I ED LE KA L AEQGQDMKWI ---- E EKQ 497
Cdd:COG4913 620 A E L E EELAEAEERLE AL EAELDA LQE R ---- RE A LQRLAEYSWDEID V AS A ERE I AE LE AE L ERLDASSDDL aale E QLE 695
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1972712332 498 A L YRRNQ EL V E KIKQMET E EA RL RH E VQD A RDQNEL L EF R ILEL E ERE R 546
Cdd:COG4913 696 E L EAELE EL E E ELDELKG E IG RL EK E LEQ A EEELDE L QD R LEAA E DLA R 744
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
421-745
2.67e-03
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 41.20
E-value: 2.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 421 K E ET EL RFRQ L TMEYQA L QRAYAL LQE QV ggtlda EREVKTR E Q L Q AE V Q RAQARI E D L EKALA E QG qdmkwi EE KQA L Y 500
Cdd:TIGR02168 220 A E LR EL ELAL L VLRLEE L REELEE LQE EL ------ KEAEEEL E E L T AE L Q ELEEKL E E L RLEVS E LE ------ EE IEE L Q 287
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 501 RRNQE L VEK I KQM E TEEAR LR HEVQDARD Q N E L LE FRIL ELE ERERKSPAIS fhh TPFVDGKSP L QVYC E AE gvtdiv V A 580
Cdd:TIGR02168 288 KELYA L ANE I SRL E QQKQI LR ERLANLER Q L E E LE AQLE ELE SKLDELAEEL --- AELEEKLEE L KEEL E SL ------ E A 358
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 581 EL MKKLDI L GDNANLTN E EQVVVIQA R TVLTLA E kwl Q QI EETEAALQ R kmvd LE SEK E LFSKQKGY L DE E LDYRKQA L D 660
Cdd:TIGR02168 359 EL EELEAE L EELESRLE E LEEQLETL R SKVAQL E --- L QI ASLNNEIE R ---- LE ARL E RLEDRRER L QQ E IEELLKK L E 431
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 661 Q A NKHI L EL E AMLYDALQQ E AGAKVAE L LSEE E REKLKVAVEQWKRQ vmse LR ER DAQI L RE R MEL L QLA Q QRIKELE E R 740
Cdd:TIGR02168 432 E A ELKE L QA E LEELEEELE E LQEELER L EEAL E ELREELEEAEQALD ---- AA ER ELAQ L QA R LDS L ERL Q ENLEGFS E G 507
....*
gi 1972712332 741 IE A QK 745
Cdd:TIGR02168 508 VK A LL 512
PRK05771
PRK05771 V-type ATP synthase subunit I; Validated
34-296
2.84e-03
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain]
Cd Length: 646
Bit Score: 41.07
E-value: 2.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 34 D IQI EL QQ E K ----- S KVS K VEREKNQ e LR QVREHEQ hktav L L T E L K T K LHEEKMK EL QAVR E TL L RQH E A E LLRVI - K 107
Cdd:PRK05771 35 D LKE EL SN E R lrklr S LLT K LSEALDK - LR SYLPKLN ----- P L R E E K K K VSVKSLE EL IKDV E EE L EKI E K E IKELE e E 108
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 108 I K -- D NE NQR L QALLSA L rdggp E KVKTVL L SEAKEEAK K GFE V EKVKMQQEIS E L kg A K RQVEEALTLV I QA DK IKAAE 185
Cdd:PRK05771 109 I S el E NE IKE L EQEIER L ----- E PWGNFD L DLSLLLGF K YVS V FVGTVPEDKL E E -- L K LESDVENVEY I ST DK GYVYV 181
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 186 IRS V YHLHQE E ITRIK K ECE re IR RL Q L D E K darrfqlki AEL S AI IR KLEDRNALLSE ER NE LL KRVR E AESQ Y kplld 265
Cdd:PRK05771 182 VVV V LKELSD E VEEEL K KLG -- FE RL E L E E E --------- GTP S EL IR EIKEELEEIEK ER ES LL EELK E LAKK Y ----- 245
250 260 270
....*....|....*....|....*....|.
gi 1972712332 266 k NKR L SRKN E D L SHA L R R M E NKL KF VTQENI 296
Cdd:PRK05771 246 - LEE L LALY E Y L EIE L E R A E ALS KF LKTDKT 275
YhaN
COG4717 Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
414-748
4.19e-03
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain]
Cd Length: 641
Bit Score: 40.52
E-value: 4.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 414 D L E E GMA K E E TE L RFRQ L TM E YQ AL QRAY A L L Q E QVG gtl DA E REVKTREQ L QA E VQRAQ A RIED L EKA L A E QGQDMKWI 493
Cdd:COG4717 113 E L R E ELE K L E KL L QLLP L YQ E LE AL EAEL A E L P E RLE --- EL E ERLEELRE L EE E LEELE A ELAE L QEE L E E LLEQLSLA 189
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 494 E E KQA -- L YRRNQ EL VEKIKQM E T E EARLRH E VQDARDQN E L LE FRILELEER ER KS ------ PAISFHHTPFVD G K S P L 565
Cdd:COG4717 190 T E EEL qd L AEELE EL QQRLAEL E E E LEEAQE E LEELEEEL E Q LE NELEAAALE ER LK earlll LIAAALLALLGL G G S L L 269
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 566 QVYCEAE GV TDI V VAE L MKKLDI L GDNANLTNE E QVVVIQARTVLT L A E KW L QQI eeteaa L QRKMVDLESEK E LFSKQK 645
Cdd:COG4717 270 SLILTIA GV LFL V LGL L ALLFLL L AREKASLGK E AEELQALPALEE L E E EE L EEL ------ L AALGLPPDLSP E ELLELL 343
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 646 GYLD E ELDYRKQ A LDQANKHI LE LEAMLYD AL QQ EAG AKVA E L L SE ----- EE REK LK VAV E QWKR Q VMSE L R E R ---- D 716
Cdd:COG4717 344 DRIE E LQELLRE A EELEEELQ LE ELEQEIA AL LA EAG VEDE E E L RA aleqa EE YQE LK EEL E ELEE Q LEEL L G E L eell E 423
330 340 350
....*....|....*....|....*....|..
gi 1972712332 717 A QILR E RM E L L QLAQQRIK ELEE RI E AQKRQI 748
Cdd:COG4717 424 A LDEE E LE E E L EELEEELE ELEE EL E ELREEL 455
Name
Accession
Description
Interval
E-value
JAKMIP_CC3
pfam16034 JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP ...
355-551
3.13e-85
JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP family (Janus kinase and microtubule-interacting proteins) and is predicted to be a coiled coil. It interacts with the Janus family kinases Tyk2 and Jak1.
Pssm-ID: 464986 [Multi-domain]
Cd Length: 199
Bit Score: 268.29
E-value: 3.13e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 355 ERDKL L R F RKQR K K MA K LPKP - V VVETFFGYDEEAS LE S DG SS V SY Q TDRTD Q TP C TPD D DL E EG M A K EE T ELRFRQLT M 433
Cdd:pfam16034 1 ERDKL I R A RKQR R K EK K KKLR d M VVETFFGYDEEAS VD S ET SS L SY N TDRTD S TP A TPD E DL D EG V A A EE A ELRFRQLT R 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 434 EYQALQRAYALLQEQ V GGTLDAERE V KTREQLQAE VQ RAQ A RIEDLE K ALA EQ GQD M KW I EEKQAL Y RRNQELVEKI KQ M 513
Cdd:pfam16034 81 EYQALQRAYALLQEQ S GGTLDAERE A KTREQLQAE LR RAQ S RIEDLE S ALA QK GQD S KW V EEKQAL I RRNQELVEKI RI M 160
170 180 190
....*....|....*....|....*....|....*...
gi 1972712332 514 E T EE A RL RH E V QDARDQNELLEFRILELEERER K SPAI 551
Cdd:pfam16034 161 E Q EE G RL KN E I QDARDQNELLEFRILELEERER R SPAI 198
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
26-545
1.59e-10
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 64.96
E-value: 1.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 26 ED L R A K L TDIQIELQQEKSKVSKV E R E KNQELRQVR E H E QHKTAVL L T EL KTK L H E EK m K EL QAVRET l LRQHE AEL L R V 105
Cdd:COG1196 223 KE L E A E L LLLKLRELEAELEELEA E L E ELEAELEEL E A E LAELEAE L E EL RLE L E E LE - L EL EEAQAE - EYELL AEL A R L 300
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 106 IKIKDNENQ R LQA L LSA L RDGGP E KVKTVLLS E AK EE AKKGF E V E KVKMQQ E IS E LKGAKRQV EEAL tlvi QADKIKA AE 185
Cdd:COG1196 301 EQDIARLEE R RRE L EER L EELEE E LAELEEEL E EL EE ELEEL E E E LEEAEE E LE E AEAELAEA EEAL ---- LEAEAEL AE 376
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 186 IRSVYHLHQ EE ITRIKKECEREIRR L QLD E KDARRFQLKIAE L SAIIRK LE DRN A L L S EE RN E LLKRVR EA ESQYKP L LD 265
Cdd:COG1196 377 AEEELEELA EE LLEALRAAAELAAQ L EEL E EAEEALLERLER L EEELEE LE EAL A E L E EE EE E EEEALE EA AEEEAE L EE 456
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 266 KNKR L SRKNED L SHALRRM E NK L KFVTQ E NI E MRQ R A giirrp SS L NDLDQSQDEREVDFLKLQIVEQQNLI -------- 337
Cdd:COG1196 457 EEEA L LELLAE L LEEAALL E AA L AELLE E LA E AAA R L ------ LL L LEAEADYEGFLEGVKAALLLAGLRGL agavavli 530
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 338 --- DELSKT LE T A ------- GY V KSVLERDKLLRFR K QR K -- KMAK LP KPVVVETFFGYDEE A SLESDGSSVSYQT D RTD 405
Cdd:COG1196 531 gve AAYEAA LE A A laaalqn IV V EDDEVAAAAIEYL K AA K ag RATF LP LDKIRARAALAAAL A RGAIGAAVDLVAS D LRE 610
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 406 QTPCTPDDDLEEGMAKEETELRFRQ L TMEYQALQ R AYALLQ E QV GG TLDAEREVKT R EQ L Q A EVQR A Q A RI E D L EKA LAE 485
Cdd:COG1196 611 ADARYYVLGDTLLGRTLVAARLEAA L RRAVTLAG R LREVTL E GE GG SAGGSLTGGS R RE L L A ALLE A E A EL E E L AER LAE 690
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 486 Q gqdmkw IE E KQALYRRNQ E LVEKIKQM E T E EARLRH E VQDARD Q N E LLEFRI LE LEER E 545
Cdd:COG1196 691 E ------ EL E LEEALLAEE E EERELAEA E E E RLEEEL E EEALEE Q L E AEREEL LE ELLE E 744
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
27-744
1.58e-09
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 61.61
E-value: 1.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 27 D L R A K L TDIQIE L Q -- QEKSKVSKV E REKNQELRQVR E H E QHKTAV ----- L L T EL KTKLH E EKMKELQAVR E TL - L RQH 98
Cdd:TIGR02168 217 E L K A E L RELELA L L vl RLEELREEL E ELQEELKEAEE E L E ELTAEL qelee K L E EL RLEVS E LEEEIEELQK E LY a L ANE 296
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 99 EAE L LRVIK I KDNENQR L QAL L SA L RDGGP E - KV K TVL L S E AKE E AKKGF E VE K VKMQQEIS EL KGAKRQV EE ALTLVIQ 177
Cdd:TIGR02168 297 ISR L EQQKQ I LRERLAN L ERQ L EE L EAQLE E l ES K LDE L A E ELA E LEEKL E EL K EELESLEA EL EELEAEL EE LESRLEE 376
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 178 ADK i KAAEI RS VYHLHQEE I TRIKK E C ER EIR RL Q ------------------- L D E KDARRF Q LKIA EL SAIIRK L EDR 238
Cdd:TIGR02168 377 LEE - QLETL RS KVAQLELQ I ASLNN E I ER LEA RL E rledrrerlqqeieellkk L E E AELKEL Q AELE EL EEELEE L QEE 455
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 239 NAL L S E ERN EL LKRVR EAE SQYKPLLDKNKR L SRKNED L SHALRRM E NKLKF V TQENIEMRQRA GI IRRP S S L NDL D q SQ 318
Cdd:TIGR02168 456 LER L E E ALE EL REELE EAE QALDAAERELAQ L QARLDS L ERLQENL E GFSEG V KALLKNQSGLS GI LGVL S E L ISV D - EG 534
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 319 D E REVD flklq IVEQQN L IDELSKT L ET A GYVKSV L ERDK L L R frkqrkk MAK LP KPVVVE T FFGYDEEAS L ESDGSSVS 398
Cdd:TIGR02168 535 Y E AAIE ----- AALGGR L QAVVVEN L NA A KKAIAF L KQNE L G R ------- VTF LP LDSIKG T EIQGNDREI L KNIEGFLG 602
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 399 YQT D RTDQT P ------------ CTPD DDL EEGMA - KEETELRF R QL T MEYQALQRAYALLQ --- EQVGGT L DAE RE V ktr 462
Cdd:TIGR02168 603 VAK D LVKFD P klrkalsyllgg VLVV DDL DNALE l AKKLRPGY R IV T LDGDLVRPGGVITG gsa KTNSSI L ERR RE I --- 679
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 463 E Q L QAEVQRAQAR I ED LEKALAE --- QGQDMK wi EE KQA L YRRNQ EL VEK I KQMETEE ARL RH EV QDARDQNEL L EFRIL 539
Cdd:TIGR02168 680 E E L EEKIEELEEK I AE LEKALAE lrk ELEELE -- EE LEQ L RKELE EL SRQ I SALRKDL ARL EA EV EQLEERIAQ L SKELT 757
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 540 ELE ERERKS paisfhhtpfvdg KSP L QVYC E AEGVTDIVVA EL MKKLDI L GDNANLTN E EQV vvi QA R TV LTL AEKWLQQ 619
Cdd:TIGR02168 758 ELE AEIEEL ------------- EER L EEAE E ELAEAEAEIE EL EAQIEQ L KEELKALR E ALD --- EL R AE LTL LNEEAAN 821
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 620 IE E TEAA L Q R KMVDL E SEK E LFSK Q KGY L D E ELDYRKQALDQANKH I L ELE AM L YDA L QQE A GAKV A EL L SEE E R E K L KV 699
Cdd:TIGR02168 822 LR E RLES L E R RIAAT E RRL E DLEE Q IEE L S E DIESLAAEIEELEEL I E ELE SE L EAL L NER A SLEE A LA L LRS E L E E L SE 901
730 740 750 760
....*....|....*....|....*....|....*....|....*
gi 1972712332 700 AVEQWKRQVMSEL RE RDA qi LRE RMEL L Q L AQQRIKELEERIEAQ 744
Cdd:TIGR02168 902 ELRELESKRSELR RE LEE -- LRE KLAQ L E L RLEGLEVRIDNLQER 944
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
26-545
1.34e-08
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 58.41
E-value: 1.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 26 E D L R A K L TDIQI EL QQEKSKV skve R E KNQ EL RQVREH E QHKT A V L LTELKTKLHE E KMKELQAV R ETL L RQHE AEL LRV 105
Cdd:COG1196 256 E E L E A E L AELEA EL EELRLEL ---- E E LEL EL EEAQAE E YELL A E L ARLEQDIARL E ERRRELEE R LEE L EEEL AEL EEE 331
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 106 IKIKDN E NQR L QAL L SALR dggpekvktvlls E AK EEA KKGFEVEKVKMQQEIS EL KG A KRQV EE ALTLVIQ A DKIK A AE 185
Cdd:COG1196 332 LEELEE E LEE L EEE L EEAE ------------- E EL EEA EAELAEAEEALLEAEA EL AE A EEEL EE LAEELLE A LRAA A EL 398
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 186 IRSVYH L HQE E ITRIKKECER E IRRLQ L D E KD A RRFQLKIA E LS A IIRKL E DRNA L LS EE RNE L LKRV -- R E AESQYKPL 263
Cdd:COG1196 399 AAQLEE L EEA E EALLERLERL E EELEE L E E AL A ELEEEEEE E EE A LEEAA E EEAE L EE EE EAL L ELLA el L E EAALLEAA 478
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 264 L DKNKRLSRKNEDLSHA L RRM E NKLKFVTQENIEMRQR AG IIRRPSSLND L DQSQDER E VDFLK - L QIVE Q QNLIDELSK 342
Cdd:COG1196 479 L AELLEELAEAAARLLL L LEA E ADYEGFLEGVKAALLL AG LRGLAGAVAV L IGVEAAY E AALEA a L AAAL Q NIVVEDDEV 558
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 343 TLETAG Y V K S - VLE R DKL L RFR K Q R KKM A KLPKPVVVETFFGY D EE AS LESDGSSVS Y QTDR T DQ - TPCTPDDDLEEGMA 420
Cdd:COG1196 559 AAAAIE Y L K A a KAG R ATF L PLD K I R ARA A LAAALARGAIGAAV D LV AS DLREADARY Y VLGD T LL g RTLVAARLEAALRR 638
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 421 KEETEL R F R QL T M E YQALQRAYA L LQEQVGGT L D A ER E VKTREQLQ AE VQRAQARIEDLEKALA E QGQDMKWIE E KQA L Y 500
Cdd:COG1196 639 AVTLAG R L R EV T L E GEGGSAGGS L TGGSRREL L A A LL E AEAELEEL AE RLAEEELELEEALLAE E EEERELAEA E EER L E 718
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 1972712332 501 RRNQ E LVEKIKQMETE E AR L RHEVQDARDQN E LLEFRIL E LEER E 545
Cdd:COG1196 719 EELE E EALEEQLEAER E EL L EELLEEEELLE E EALEELP E PPDL E 763
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
158-749
3.66e-08
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 57.25
E-value: 3.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 158 ISE L KGAKRQV E EALT L VIQADKIK A AEIRSVYHLHQE E ITRIKK E C E REIRR L QLD E KDARRFQLKIA EL SAIIRK LE D 237
Cdd:COG1196 202 LEP L ERQAEKA E RYRE L KEELKELE A ELLLLKLRELEA E LEELEA E L E ELEAE L EEL E AELAELEAELE EL RLELEE LE L 281
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 238 RNALLSE E RN ELL KRVREA E SQYKP L LDKNKR L SRKN E D L SHA L RRM E NK L KFVTQ E NI E MRQRAGIIRRP ----- SS L N 312
Cdd:COG1196 282 ELEEAQA E EY ELL AELARL E QDIAR L EERRRE L EERL E E L EEE L AEL E EE L EELEE E LE E LEEELEEAEEE leeae AE L A 361
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 313 DLDQSQD E R E VDFLKLQIVEQQNLIDE L SKTLET A GYVKSVL E RDKLLRFRKQ R KKMAK lpkpvvvetffgy D E EAS LE S 392
Cdd:COG1196 362 EAEEALL E A E AELAEAEEELEELAEEL L EALRAA A ELAAQLE E LEEAEEALLE R LERLE ------------- E E LEE LE E 428
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 393 DGSSVSYQTDRTDQT pctpdd DL E EGMAKE E T E LRFRQ L TMEYQA L QRAY ALL QEQVGGT L DAER E VKT R EQ L QA E VQR - 471
Cdd:COG1196 429 ALAELEEEEEEEEEA ------ LE E AAEEEA E L E EEEEA L LELLAE L LEEA ALL EAALAEL L EELA E AAA R LL L LL E AEA d 502
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 472 AQARI E DLEK AL AEQ G QDMKWIEE kq A LYRRNQELV E KIKQMETEE A RLRHE V Q D ARDQNELL E FRILELEE R ERKS P AI 551
Cdd:COG1196 503 YEGFL E GVKA AL LLA G LRGLAGAV -- A VLIGVEAAY E AALEAALAA A LQNIV V E D DEVAAAAI E YLKAAKAG R ATFL P LD 580
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 552 SFHHTPFVDGKSPLQVYCE A EGVTDIVVA E LMKKLDI LGD NA nltneeq VVVIQARTV L TL A EKWLQQIEETEAALQRKM 631
Cdd:COG1196 581 KIRARAALAAALARGAIGA A VDLVASDLR E ADARYYV LGD TL ------- LGRTLVAAR L EA A LRRAVTLAGRLREVTLEG 653
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 632 VDLESEKE L FSKQKGY L DEE L DYRKQA L DQANKHIL E L E AM L YD AL QQ E AGAKVAELLS EEER EKLKVAV E QWKR Q VMS E 711
Cdd:COG1196 654 EGGSAGGS L TGGSRRE L LAA L LEAEAE L EELAERLA E E E LE L EE AL LA E EEEERELAEA EEER LEEELEE E ALEE Q LEA E 733
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 1972712332 712 LR E RDAQI L R E RME L LQL A QQ ------ RIK ELE ERI E AQK R Q I K 749
Cdd:COG1196 734 RE E LLEEL L E E EEL L EEE A LE elpepp DLE ELE REL E RLE R E I E 777
SMC_prok_A
TIGR02169 chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
50-749
4.61e-07
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain]
Cd Length: 1164
Bit Score: 53.53
E-value: 4.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 50 E R EK NQ E LRQVR E HEQHKTAV LL T EL KT K LHEEKMK E LQA V R E TL l RQH EAE LLRVIKIKDNENQR L QALLSA L RDGGP E 129
Cdd:TIGR02169 252 E L EK LT E EISEL E KRLEEIEQ LL E EL NK K IKDLGEE E QLR V K E KI - GEL EAE IASLERSIAEKERE L EDAEER L AKLEA E 330
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 130 KV K TVLLS E AK E EAKKGFEVEKV K MQQ E IS ELK gakr QVE E A L TLVIQADKIKA AE I R SVYHLHQ E EITRI K K E CEREI R 209
Cdd:TIGR02169 331 ID K LLAEI E EL E REIEEERKRRD K LTE E YA ELK ---- EEL E D L RAELEEVDKEF AE T R DELKDYR E KLEKL K R E INELK R 406
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 210 R L QLDEKDAR R FQLKI A E L S A I I RKL E DRNAL L S EE RNELLKRVREA E SQYKP L LDKNKRLSRKNE DL SHALR R M E NK L K 289
Cdd:TIGR02169 407 E L DRLQEELQ R LSEEL A D L N A A I AGI E AKINE L E EE KEDKALEIKKQ E WKLEQ L AADLSKYEQELY DL KEEYD R V E KE L S 486
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 290 FVTQ E NI E MRQR A GIIRRPSSLNDLDQSQDEREVDFLKLQIVEQQNLIDELSKTL E T A G ------- Y V KSVLERDKLLRF 362
Cdd:TIGR02169 487 KLQR E LA E AEAQ A RASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAI E V A A gnrlnnv V V EDDAVAKEAIEL 566
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 363 R K Q RK ---------- KM AKLPKPVVVETFF G YDEE A ---- SLESDGSSVSYQTDRTDQTP ctpd D D L E EG mak EETELRF 428
Cdd:TIGR02169 567 L K R RK agratflpln KM RDERRDLSILSED G VIGF A vdlv EFDPKYEPAFKYVFGDTLVV ---- E D I E AA --- RRLMGKY 639
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 429 R QL T M E YQALQRAY A L lqeq V GG TLDAEREVKTREQLQ AE V QR AQA R I E D L EKA L AEQGQDMKW IE ek QA L YRRN QEL VE 508
Cdd:TIGR02169 640 R MV T L E GELFEKSG A M ---- T GG SRAPRGGILFSRSEP AE L QR LRE R L E G L KRE L SSLQSELRR IE -- NR L DELS QEL SD 713
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 509 KIKQMETE E ARLRHEV Q DARDQN E L LE FRILE L EER E RKSPAI sfhhtpfvdg KS P L Q vyc E A E GVTDIVVAE L M K KLDI 588
Cdd:TIGR02169 714 ASRKIGEI E KEIEQLE Q EEEKLK E R LE ELEED L SSL E QEIENV ---------- KS E L K --- E L E ARIEELEED L H K LEEA 780
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 589 L G D NANLTNEEQVVV IQA R tv L TLA E KWLQQ IE ETEAALQR K MVD L ES EKE LFS K QKGY L D E ELDYR K QALDQAN K H I LE 668
Cdd:TIGR02169 781 L N D LEARLSHSRIPE IQA E -- L SKL E EEVSR IE ARLREIEQ K LNR L TL EKE YLE K EIQE L Q E QRIDL K EQIKSIE K E I EN 858
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 669 L EAMLYDALQQEAGAKV A ELLS E EEREK LK VAVEQWKR Q v MS EL RER daqi LR E RMELLQLAQQ R IK EL EERI EA QKRQI 748
Cdd:TIGR02169 859 L NGKKEELEEELEELEA A LRDL E SRLGD LK KERDELEA Q - LR EL ERK ---- IE E LEAQIEKKRK R LS EL KAKL EA LEEEL 933
.
gi 1972712332 749 K 749
Cdd:TIGR02169 934 S 934
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
26-521
1.21e-04
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 45.70
E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 26 E DLRAK L TDIQI EL QQEKSKVSKV E R E KNQELRQVR E HEQHKTAV L LTELKTKLHE E KMK E LQAVRETL L RQH E A EL LRV 105
Cdd:COG1196 347 E EAEEE L EEAEA EL AEAEEALLEA E A E LAEAEEELE E LAEELLEA L RAAAELAAQL E ELE E AEEALLER L ERL E E EL EEL 426
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 106 IKIKDNENQRLQALLS AL RDGGP E KVKTVLLS EA KE E AKKGFEV E KVKMQQEIS EL KGAKRQVEEA L T L VIQ A DKIKAAE 185
Cdd:COG1196 427 EEALAELEEEEEEEEE AL EEAAE E EAELEEEE EA LL E LLAELLE E AALLEAALA EL LEELAEAAAR L L L LLE A EADYEGF 506
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 186 IRS V YHLHQEEIT R IKKECEREIRRLQLDEKD A RR fqlki A E L S A IIRKLEDRNALLSEERN E L LK RVREAESQYK PL LD 265
Cdd:COG1196 507 LEG V KAALLLAGL R GLAGAVAVLIGVEAAYEA A LE ----- A A L A A ALQNIVVEDDEVAAAAI E Y LK AAKAGRATFL PL DK 581
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 266 KNK R LSRKNEDLSH A LRRMENKLKFVTQ E NIEMRQRA G IIRRPSS L NDLDQSQDE R EVDF L KLQIV E QQNLIDEL S KTLE 345
Cdd:COG1196 582 IRA R AALAAALARG A IGAAVDLVASDLR E ADARYYVL G DTLLGRT L VAARLEAAL R RAVT L AGRLR E VTLEGEGG S AGGS 661
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 346 TA G YVKSV L ERDK L LRFRKQRKKMAK L pkpvvvetffg YD EE AS LE SDGSSVSYQTDRTDQ tpctp DDDLEEGMAK EE TE 425
Cdd:COG1196 662 LT G GSRRE L LAAL L EAEAELEELAER L ----------- AE EE LE LE EALLAEEEEERELAE ----- AEEERLEEEL EE EA 725
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 426 L RFRQLTMEYQA L QRAYALLQEQVGGT L DAER E VKTR E Q L QA E VQ R AQAR IE D L EK -- A LA eqgqdmkw IEE KQA L YR R N 503
Cdd:COG1196 726 L EEQLEAEREEL L EELLEEEELLEEEA L EELP E PPDL E E L ER E LE R LERE IE A L GP vn L LA -------- IEE YEE L EE R Y 797
490
....*....|....*...
gi 1972712332 504 QE L V E KIKQM E TEEAR L R 521
Cdd:COG1196 798 DF L S E QREDL E EARET L E 815
EnvC
COG4942 Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
26-240
1.73e-03
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain]
Cd Length: 377
Bit Score: 41.29
E-value: 1.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 26 EDLR A K L TDI Q I E LQQEKSKVSKVER E KNQE L R Q VREH E QH ---- KTAVLLT E LKTKLH E EKMK EL QAVRET L LRQH E -- 99
Cdd:COG4942 23 AEAE A E L EQL Q Q E IAELEKELAALKK E EKAL L K Q LAAL E RR iaal ARRIRAL E QELAAL E AELA EL EKEIAE L RAEL E aq 102
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 100 ---- AELLR VI k IKDNENQR L QA LLS A lr DGGPEK V KTVLLSEAKEE A KKGFEV E KVKMQQ E ISE L KGAKRQVEEA L TLV 175
Cdd:COG4942 103 keel AELLR AL - YRLGRQPP L AL LLS P -- EDFLDA V RRLQYLKYLAP A RREQAE E LRADLA E LAA L RAELEAERAE L EAL 179
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1972712332 176 IQADKIKA A EIRSVYHLH Q EEIT R IK KE CEREIRR L QLDEKD A RRFQLK IA E L S A IIRKLED R NA 240
Cdd:COG4942 180 LAELEEER A ALEALKAER Q KLLA R LE KE LAELAAE L AELQQE A EELEAL IA R L E A EAAAAAE R TP 244
COG4913
COG4913 Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
422-546
2.61e-03
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain]
Cd Length: 1089
Bit Score: 41.44
E-value: 2.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 422 E E T E LRFRQLTMEYQ AL QRAYAL LQE Q vggt LD A EREVKTREQLQAE V QR A QAR I ED LE KA L AEQGQDMKWI ---- E EKQ 497
Cdd:COG4913 620 A E L E EELAEAEERLE AL EAELDA LQE R ---- RE A LQRLAEYSWDEID V AS A ERE I AE LE AE L ERLDASSDDL aale E QLE 695
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1972712332 498 A L YRRNQ EL V E KIKQMET E EA RL RH E VQD A RDQNEL L EF R ILEL E ERE R 546
Cdd:COG4913 696 E L EAELE EL E E ELDELKG E IG RL EK E LEQ A EEELDE L QD R LEAA E DLA R 744
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
421-745
2.67e-03
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 41.20
E-value: 2.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 421 K E ET EL RFRQ L TMEYQA L QRAYAL LQE QV ggtlda EREVKTR E Q L Q AE V Q RAQARI E D L EKALA E QG qdmkwi EE KQA L Y 500
Cdd:TIGR02168 220 A E LR EL ELAL L VLRLEE L REELEE LQE EL ------ KEAEEEL E E L T AE L Q ELEEKL E E L RLEVS E LE ------ EE IEE L Q 287
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 501 RRNQE L VEK I KQM E TEEAR LR HEVQDARD Q N E L LE FRIL ELE ERERKSPAIS fhh TPFVDGKSP L QVYC E AE gvtdiv V A 580
Cdd:TIGR02168 288 KELYA L ANE I SRL E QQKQI LR ERLANLER Q L E E LE AQLE ELE SKLDELAEEL --- AELEEKLEE L KEEL E SL ------ E A 358
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 581 EL MKKLDI L GDNANLTN E EQVVVIQA R TVLTLA E kwl Q QI EETEAALQ R kmvd LE SEK E LFSKQKGY L DE E LDYRKQA L D 660
Cdd:TIGR02168 359 EL EELEAE L EELESRLE E LEEQLETL R SKVAQL E --- L QI ASLNNEIE R ---- LE ARL E RLEDRRER L QQ E IEELLKK L E 431
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 661 Q A NKHI L EL E AMLYDALQQ E AGAKVAE L LSEE E REKLKVAVEQWKRQ vmse LR ER DAQI L RE R MEL L QLA Q QRIKELE E R 740
Cdd:TIGR02168 432 E A ELKE L QA E LEELEEELE E LQEELER L EEAL E ELREELEEAEQALD ---- AA ER ELAQ L QA R LDS L ERL Q ENLEGFS E G 507
....*
gi 1972712332 741 IE A QK 745
Cdd:TIGR02168 508 VK A LL 512
PRK05771
PRK05771 V-type ATP synthase subunit I; Validated
34-296
2.84e-03
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain]
Cd Length: 646
Bit Score: 41.07
E-value: 2.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 34 D IQI EL QQ E K ----- S KVS K VEREKNQ e LR QVREHEQ hktav L L T E L K T K LHEEKMK EL QAVR E TL L RQH E A E LLRVI - K 107
Cdd:PRK05771 35 D LKE EL SN E R lrklr S LLT K LSEALDK - LR SYLPKLN ----- P L R E E K K K VSVKSLE EL IKDV E EE L EKI E K E IKELE e E 108
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 108 I K -- D NE NQR L QALLSA L rdggp E KVKTVL L SEAKEEAK K GFE V EKVKMQQEIS E L kg A K RQVEEALTLV I QA DK IKAAE 185
Cdd:PRK05771 109 I S el E NE IKE L EQEIER L ----- E PWGNFD L DLSLLLGF K YVS V FVGTVPEDKL E E -- L K LESDVENVEY I ST DK GYVYV 181
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 186 IRS V YHLHQE E ITRIK K ECE re IR RL Q L D E K darrfqlki AEL S AI IR KLEDRNALLSE ER NE LL KRVR E AESQ Y kplld 265
Cdd:PRK05771 182 VVV V LKELSD E VEEEL K KLG -- FE RL E L E E E --------- GTP S EL IR EIKEELEEIEK ER ES LL EELK E LAKK Y ----- 245
250 260 270
....*....|....*....|....*....|.
gi 1972712332 266 k NKR L SRKN E D L SHA L R R M E NKL KF VTQENI 296
Cdd:PRK05771 246 - LEE L LALY E Y L EIE L E R A E ALS KF LKTDKT 275
PRK08332
PRK08332 vitamin B12-dependent ribonucleotide reductase;
131-373
3.52e-03
vitamin B12-dependent ribonucleotide reductase;
Pssm-ID: 181392 [Multi-domain]
Cd Length: 1740
Bit Score: 40.90
E-value: 3.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 131 V KTVLLSEAKEEA KK GF EV E K v KMQ Q E I S EL KGA K RQVE E ALTLVIQADKIK A A -- E IRSV Y H L HQEEITR I KK E CE R EI 208
Cdd:PRK08332 25 V QRAMWEVGVRDE KK LD EV V K - RIV Q R I N EL YDG K IPHI E NIQDIVELELMR A G lf E VAKA Y I L YRKKKAE I RE E KK R IL 103
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 209 RRLQ LDE K D a R RF QLKIAELS A IIRKLE D R N ALLS E ERN EL LK RV re A ESQYK P L L DKNK R LSR KN EDL S HA L R R M E NK L 288
Cdd:PRK08332 104 NKKE LDE I D - K RF SINALRVL A SRYLKK D E N GNII E SPR EL FE RV -- A ILAVI P D L LYDE R VFD KN GNY S QD L K R V E YY L 180
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 289 kfvtq EN I E MRQRAGI I RR pssl ND L DQSQD ER E V DFLK l QIV E QQNL --- IDE LS K T LE TAGYV K SVL E RDKLL R FRKQ 365
Cdd:PRK08332 181 ----- EN F E EFDGKYS I GK ---- YK L NKYHF ER M V NLYR - ELA E KGKM kvs IDE FL K M LE RGEFD K YEK E IEEYF R LMTN 250
....*...
gi 1972712332 366 RKK M AKL P 373
Cdd:PRK08332 251 QIF M PNT P 258
COG2433
COG2433 Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
454-543
4.02e-03
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain]
Cd Length: 644
Bit Score: 40.61
E-value: 4.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 454 DA E REVKTR E -- Q L QAE V Q R AQ A RI E D LE KA L A E QGQDMKWI E EKQALY R RNQELV ---- EK I KQMET E EA RL RH E VQDA 527
Cdd:COG2433 405 ER E LTEEEE E ir R L EEQ V E R LE A EV E E LE AE L E E KDERIERL E RELSEA R SEERRE irkd RE I SRLDR E IE RL ER E LEEE 484
90
....*....|....*.
gi 1972712332 528 R DQN E L L EFRILE L E E 543
Cdd:COG2433 485 R ERI E E L KRKLER L K E 500
YhaN
COG4717 Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
414-748
4.19e-03
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain]
Cd Length: 641
Bit Score: 40.52
E-value: 4.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 414 D L E E GMA K E E TE L RFRQ L TM E YQ AL QRAY A L L Q E QVG gtl DA E REVKTREQ L QA E VQRAQ A RIED L EKA L A E QGQDMKWI 493
Cdd:COG4717 113 E L R E ELE K L E KL L QLLP L YQ E LE AL EAEL A E L P E RLE --- EL E ERLEELRE L EE E LEELE A ELAE L QEE L E E LLEQLSLA 189
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 494 E E KQA -- L YRRNQ EL VEKIKQM E T E EARLRH E VQDARDQN E L LE FRILELEER ER KS ------ PAISFHHTPFVD G K S P L 565
Cdd:COG4717 190 T E EEL qd L AEELE EL QQRLAEL E E E LEEAQE E LEELEEEL E Q LE NELEAAALE ER LK earlll LIAAALLALLGL G G S L L 269
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 566 QVYCEAE GV TDI V VAE L MKKLDI L GDNANLTNE E QVVVIQARTVLT L A E KW L QQI eeteaa L QRKMVDLESEK E LFSKQK 645
Cdd:COG4717 270 SLILTIA GV LFL V LGL L ALLFLL L AREKASLGK E AEELQALPALEE L E E EE L EEL ------ L AALGLPPDLSP E ELLELL 343
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 646 GYLD E ELDYRKQ A LDQANKHI LE LEAMLYD AL QQ EAG AKVA E L L SE ----- EE REK LK VAV E QWKR Q VMSE L R E R ---- D 716
Cdd:COG4717 344 DRIE E LQELLRE A EELEEELQ LE ELEQEIA AL LA EAG VEDE E E L RA aleqa EE YQE LK EEL E ELEE Q LEEL L G E L eell E 423
330 340 350
....*....|....*....|....*....|..
gi 1972712332 717 A QILR E RM E L L QLAQQRIK ELEE RI E AQKRQI 748
Cdd:COG4717 424 A LDEE E LE E E L EELEEELE ELEE EL E ELREEL 455
PTZ00121
PTZ00121 MAEBL; Provisional
41-265
6.40e-03
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 40.12
E-value: 6.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 41 Q EK S K VS --- K V E RE KN QE LR QVR E HEQHKT A VLLTEL K TKLH E E KMK ELQ A VRET ------- L L RQH E A E LLR V IKI K D 110
Cdd:PTZ00121 1561 E EK K K AE eak K A E ED KN MA LR KAE E AKKAEE A RIEEVM K LYEE E K KMK AEE A KKAE eakikae E L KKA E E E KKK V EQL K K 1640
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 111 N E NQRLQALLSALRDGGPE K V K TVLLSEAK EE A KK GF E VE K VKMQQ E ISELKGA K RQV EEA ----- L TLVIQAD K I KA A E 185
Cdd:PTZ00121 1641 K E AEEKKKAEELKKAEEEN K I K AAEEAKKA EE D KK KA E EA K KAEED E KKAAEAL K KEA EEA kkaee L KKKEAEE K K KA E E 1720
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 186 IRSVYHLHQEEITRI KKE C E REIRR --- LQL DE KDARRF - Q LK IA E LSAIIRKLEDRN A LLS EE - RN E LL KR VR E AESQY 260
Cdd:PTZ00121 1721 LKKAEEENKIKAEEA KKE A E EDKKK aee AKK DE EEKKKI a H LK KE E EKKAEEIRKEKE A VIE EE l DE E DE KR RM E VDKKI 1800
....*
gi 1972712332 261 K PLL D 265
Cdd:PTZ00121 1801 K DIF D 1805
235kDa-fam
TIGR01612 reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
25-307
8.14e-03
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain]
Cd Length: 2757
Bit Score: 40.03
E-value: 8.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 25 N EDLR AKL T D IQIELQQ E KS K VSKV E REKNQELRQVR E HEQHKTAVLLT E L K TKL H E E KM K E L QAVR E T l LRQH E A EL LR 104
Cdd:TIGR01612 691 N TEDK AKL D D LKSKIDK E YD K IQNM E TATVELHLSNI E NKKNELLDIIV E I K KHI H G E IN K D L NKIL E D - FKNK E K EL SN 769
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 105 V I KIKDN E NQR L QALL S ALRDGGPEKVKTVLLSEA K - E E AK KGFE ---------- VEKVKMQQE I S E L K GA K RQVEEALT 173
Cdd:TIGR01612 770 K I NDYAK E KDE L NKYK S KISEIKNHYNDQINIDNI K d E D AK QNYD kskeyiktis IKEDEIFKI I N E M K FM K DDFLNKVD 849
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972712332 174 LV I QADKIKAAE I R S VYHLHQ E EITR IK K E CERE irrlqldekdarrf Q L KIA E lsaii R K LE D RNA L LS E ERNELLKRV 253
Cdd:TIGR01612 850 KF I NFENNCKEK I D S EHEQFA E LTNK IK A E ISDD -------------- K L NDY E ----- K K FN D SKS L IN E INKSIEEEY 910
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1972712332 254 REAESQY K pl L D KNKRLSRKNEDLSHALRRME N K LK FVTQE NI EMRQRAGI I RR 307
Cdd:TIGR01612 911 QNINTLK K -- V D EYIKICENTKESIEKFHNKQ N I LK EILNK NI DTIKESNL I EK 962
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
