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Concise Results
Standard Results
Full Results
janus kinase and microtubule-interacting protein 3 isoform j [Homo sapiens]
Protein Classification
SMC_prok_B and JAKMIP_CC3 domain-containing protein ( domain architecture ID 13531091 )
SMC_prok_B and JAKMIP_CC3 domain-containing protein
List of domain hits
Name
Accession
Description
Interval
E-value
JAKMIP_CC3
pfam16034 JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP ...
426-622
3.00e-86
JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP family (Janus kinase and microtubule-interacting proteins) and is predicted to be a coiled coil. It interacts with the Janus family kinases Tyk2 and Jak1.
Pssm-ID: 464986 [Multi-domain]
Cd Length: 199
Bit Score: 272.52
E-value: 3.00e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 426 ERDKL L R F RKQR K K MA K LPKP - V VVETFFGYDEEAS LE S DG SS V SY Q TDRTD Q TP C TPD D DL E EG M A K EE T ELRFRQLT M 504
Cdd:pfam16034 1 ERDKL I R A RKQR R K EK K KKLR d M VVETFFGYDEEAS VD S ET SS L SY N TDRTD S TP A TPD E DL D EG V A A EE A ELRFRQLT R 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 505 EYQALQRAYALLQEQ V GGTLDAERE V KTREQLQAE VQ RAQ A RIEDLE K ALA EQ GQD M KW I EEKQAL Y RRNQELVEKI KQ M 584
Cdd:pfam16034 81 EYQALQRAYALLQEQ S GGTLDAERE A KTREQLQAE LR RAQ S RIEDLE S ALA QK GQD S KW V EEKQAL I RRNQELVEKI RI M 160
170 180 190
....*....|....*....|....*....|....*...
gi 1972711173 585 E T EE A RL RH E V QDARDQNELLEFRILELEERER K SPAI 622
Cdd:pfam16034 161 E Q EE G RL KN E I QDARDQNELLEFRILELEERER R SPAI 198
SMC_prok_B super family
cl37069 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
27-815
6.26e-09
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
TIGR02168 :Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 60.07
E-value: 6.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 27 D L R A K L TDIQIE L Q -- QEKSKVSKV E REKNQELRQVR E H E QHKTAVLLT E L K tkl H EE KMK E LQAVR E TLLRQ h EA EL LR 104
Cdd:TIGR02168 217 E L K A E L RELELA L L vl RLEELREEL E ELQEELKEAEE E L E ELTAELQEL E E K --- L EE LRL E VSELE E EIEEL - QK EL YA 292
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 105 VIKIKDNEN Q RL Q A L LSA L RDGGPEKVKTVLLS E AK E EAKKGFEV E KVKMQQEIS ELK GAKRQV E EA L tlviqadkikaa 184
Cdd:TIGR02168 293 LANEISRLE Q QK Q I L RER L ANLERQLEELEAQL E EL E SKLDELAE E LAELEEKLE ELK EELESL E AE L ------------ 360
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 185 eirsvyhlhq EE ITRIKK E C E REIRR L M E EIKFKDRA V FV LE RELGVQAGHAQ RL QLQK E A L DEQLSQVREA drhpgsp R 264
Cdd:TIGR02168 361 ---------- EE LEAELE E L E SRLEE L E E QLETLRSK V AQ LE LQIASLNNEIE RL EARL E R L EDRRERLQQE ------- I 423
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 265 R EL phaagagdasdhs GSP L D E KDARRF Q LKIA EL SAIIRK L EDRNAL L S E ERN EL LKRVR EAE SQYKPLLDKNKR L SRK 344
Cdd:TIGR02168 424 E EL ------------- LKK L E E AELKEL Q AELE EL EEELEE L QEELER L E E ALE EL REELE EAE QALDAAERELAQ L QAR 490
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 345 NED L SHALRRM E NKLKF V TQENIEMRQRA GI IRRP S S L NDL D q SQD E REVD flklq IVEQQN L IDELSKT L ET A GYVKSV 424
Cdd:TIGR02168 491 LDS L ERLQENL E GFSEG V KALLKNQSGLS GI LGVL S E L ISV D - EGY E AAIE ----- AALGGR L QAVVVEN L NA A KKAIAF 564
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 425 L ERDK L L R frkqrkk MAK LP KPVVVE T FFGYDEEAS L ESDGSSVSYQT D RTDQT P ------------ CTPD DDL EEGMA - 491
Cdd:TIGR02168 565 L KQNE L G R ------- VTF LP LDSIKG T EIQGNDREI L KNIEGFLGVAK D LVKFD P klrkalsyllgg VLVV DDL DNALE l 637
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 492 KEETELRF R QL T MEYQALQRAYALLQ --- EQVGGT L DAE RE V ktr E Q L QAEVQRAQAR I ED LEKALAE --- QGQDMK wi E 565
Cdd:TIGR02168 638 AKKLRPGY R IV T LDGDLVRPGGVITG gsa KTNSSI L ERR RE I --- E E L EEKIEELEEK I AE LEKALAE lrk ELEELE -- E 712
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 566 E KQA L YRRNQ EL VEK I KQMETEE ARL RH EV QDARDQNEL L EFRIL ELE ERERKSPAI sfhhtpf VDGKSPLQVYC EAE gv 645
Cdd:TIGR02168 713 E LEQ L RKELE EL SRQ I SALRKDL ARL EA EV EQLEERIAQ L SKELT ELE AEIEELEER ------- LEEAEEELAEA EAE -- 783
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 646 tdiv VA EL MKKLDI L GDNANLTN E EQV vvi QA R TV LTL AEKWLQQIE E TEAA L Q R KMVDL E SEK E LFSK Q KGY L D E ELDY 725
Cdd:TIGR02168 784 ---- IE EL EAQIEQ L KEELKALR E ALD --- EL R AE LTL LNEEAANLR E RLES L E R RIAAT E RRL E DLEE Q IEE L S E DIES 856
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 726 RKQALDQANKH I L ELE AM L YDA L QQE A GAKV A EL L SEE E R E K L KVAVEQWKRQVMSEL RE RDA qi LRE RMEL L Q L AQQRI 805
Cdd:TIGR02168 857 LAAEIEELEEL I E ELE SE L EAL L NER A SLEE A LA L LRS E L E E L SEELRELESKRSELR RE LEE -- LRE KLAQ L E L RLEGL 934
810
....*....|
gi 1972711173 806 KELEERIEAQ 815
Cdd:TIGR02168 935 EVRIDNLQER 944
Name
Accession
Description
Interval
E-value
JAKMIP_CC3
pfam16034 JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP ...
426-622
3.00e-86
JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP family (Janus kinase and microtubule-interacting proteins) and is predicted to be a coiled coil. It interacts with the Janus family kinases Tyk2 and Jak1.
Pssm-ID: 464986 [Multi-domain]
Cd Length: 199
Bit Score: 272.52
E-value: 3.00e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 426 ERDKL L R F RKQR K K MA K LPKP - V VVETFFGYDEEAS LE S DG SS V SY Q TDRTD Q TP C TPD D DL E EG M A K EE T ELRFRQLT M 504
Cdd:pfam16034 1 ERDKL I R A RKQR R K EK K KKLR d M VVETFFGYDEEAS VD S ET SS L SY N TDRTD S TP A TPD E DL D EG V A A EE A ELRFRQLT R 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 505 EYQALQRAYALLQEQ V GGTLDAERE V KTREQLQAE VQ RAQ A RIEDLE K ALA EQ GQD M KW I EEKQAL Y RRNQELVEKI KQ M 584
Cdd:pfam16034 81 EYQALQRAYALLQEQ S GGTLDAERE A KTREQLQAE LR RAQ S RIEDLE S ALA QK GQD S KW V EEKQAL I RRNQELVEKI RI M 160
170 180 190
....*....|....*....|....*....|....*...
gi 1972711173 585 E T EE A RL RH E V QDARDQNELLEFRILELEERER K SPAI 622
Cdd:pfam16034 161 E Q EE G RL KN E I QDARDQNELLEFRILELEERER R SPAI 198
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
27-815
6.26e-09
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 60.07
E-value: 6.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 27 D L R A K L TDIQIE L Q -- QEKSKVSKV E REKNQELRQVR E H E QHKTAVLLT E L K tkl H EE KMK E LQAVR E TLLRQ h EA EL LR 104
Cdd:TIGR02168 217 E L K A E L RELELA L L vl RLEELREEL E ELQEELKEAEE E L E ELTAELQEL E E K --- L EE LRL E VSELE E EIEEL - QK EL YA 292
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 105 VIKIKDNEN Q RL Q A L LSA L RDGGPEKVKTVLLS E AK E EAKKGFEV E KVKMQQEIS ELK GAKRQV E EA L tlviqadkikaa 184
Cdd:TIGR02168 293 LANEISRLE Q QK Q I L RER L ANLERQLEELEAQL E EL E SKLDELAE E LAELEEKLE ELK EELESL E AE L ------------ 360
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 185 eirsvyhlhq EE ITRIKK E C E REIRR L M E EIKFKDRA V FV LE RELGVQAGHAQ RL QLQK E A L DEQLSQVREA drhpgsp R 264
Cdd:TIGR02168 361 ---------- EE LEAELE E L E SRLEE L E E QLETLRSK V AQ LE LQIASLNNEIE RL EARL E R L EDRRERLQQE ------- I 423
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 265 R EL phaagagdasdhs GSP L D E KDARRF Q LKIA EL SAIIRK L EDRNAL L S E ERN EL LKRVR EAE SQYKPLLDKNKR L SRK 344
Cdd:TIGR02168 424 E EL ------------- LKK L E E AELKEL Q AELE EL EEELEE L QEELER L E E ALE EL REELE EAE QALDAAERELAQ L QAR 490
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 345 NED L SHALRRM E NKLKF V TQENIEMRQRA GI IRRP S S L NDL D q SQD E REVD flklq IVEQQN L IDELSKT L ET A GYVKSV 424
Cdd:TIGR02168 491 LDS L ERLQENL E GFSEG V KALLKNQSGLS GI LGVL S E L ISV D - EGY E AAIE ----- AALGGR L QAVVVEN L NA A KKAIAF 564
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 425 L ERDK L L R frkqrkk MAK LP KPVVVE T FFGYDEEAS L ESDGSSVSYQT D RTDQT P ------------ CTPD DDL EEGMA - 491
Cdd:TIGR02168 565 L KQNE L G R ------- VTF LP LDSIKG T EIQGNDREI L KNIEGFLGVAK D LVKFD P klrkalsyllgg VLVV DDL DNALE l 637
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 492 KEETELRF R QL T MEYQALQRAYALLQ --- EQVGGT L DAE RE V ktr E Q L QAEVQRAQAR I ED LEKALAE --- QGQDMK wi E 565
Cdd:TIGR02168 638 AKKLRPGY R IV T LDGDLVRPGGVITG gsa KTNSSI L ERR RE I --- E E L EEKIEELEEK I AE LEKALAE lrk ELEELE -- E 712
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 566 E KQA L YRRNQ EL VEK I KQMETEE ARL RH EV QDARDQNEL L EFRIL ELE ERERKSPAI sfhhtpf VDGKSPLQVYC EAE gv 645
Cdd:TIGR02168 713 E LEQ L RKELE EL SRQ I SALRKDL ARL EA EV EQLEERIAQ L SKELT ELE AEIEELEER ------- LEEAEEELAEA EAE -- 783
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 646 tdiv VA EL MKKLDI L GDNANLTN E EQV vvi QA R TV LTL AEKWLQQIE E TEAA L Q R KMVDL E SEK E LFSK Q KGY L D E ELDY 725
Cdd:TIGR02168 784 ---- IE EL EAQIEQ L KEELKALR E ALD --- EL R AE LTL LNEEAANLR E RLES L E R RIAAT E RRL E DLEE Q IEE L S E DIES 856
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 726 RKQALDQANKH I L ELE AM L YDA L QQE A GAKV A EL L SEE E R E K L KVAVEQWKRQVMSEL RE RDA qi LRE RMEL L Q L AQQRI 805
Cdd:TIGR02168 857 LAAEIEELEEL I E ELE SE L EAL L NER A SLEE A LA L LRS E L E E L SEELRELESKRSELR RE LEE -- LRE KLAQ L E L RLEGL 934
810
....*....|
gi 1972711173 806 KELEERIEAQ 815
Cdd:TIGR02168 935 EVRIDNLQER 944
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
492-818
3.15e-08
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 57.64
E-value: 3.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 492 K E ET EL RFRQ L TMEYQA L QRAYAL L QEQVG - GTLDA E REVKTREQ L Q AE VQRAQARI E D LE KA L A E - Q GQDMKWIE E KQA 569
Cdd:COG1196 220 E E LK EL EAEL L LLKLRE L EAELEE L EAELE e LEAEL E ELEAELAE L E AE LEELRLEL E E LE LE L E E a Q AEEYELLA E LAR 299
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 570 L YRRNQE L V E KIKQM E TEEAR L RH E VQDARDQN E L LE FRIL ELEE RE rkspaisfhhtpfvdgksplqvyceaegvtdiv 649
Cdd:COG1196 300 L EQDIAR L E E RRREL E ERLEE L EE E LAELEEEL E E LE EELE ELEE EL --------------------------------- 346
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 650 v A E LMKK L D ilgdnanltn E EQVVVIQ A RTV L TL AE KW L QQI EE TEAA L QRKMVDLESEKELFSK Q KGY L D E ELDYRKQA 729
Cdd:COG1196 347 - E E AEEE L E ---------- E AEAELAE A EEA L LE AE AE L AEA EE ELEE L AEELLEALRAAAELAA Q LEE L E E AEEALLER 415
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 730 L DQANKHIL ELE AM L YDALQQ E AGAKV A ELLSE EE REK L KVAV E Q w KRQVMS EL R E RD A QILRERM ELL QLAQQRIKE L E 809
Cdd:COG1196 416 L ERLEEELE ELE EA L AELEEE E EEEEE A LEEAA EE EAE L EEEE E A - LLELLA EL L E EA A LLEAALA ELL EELAEAAAR L L 494
....*....
gi 1972711173 810 ERI EA QKRQ 818
Cdd:COG1196 495 LLL EA EADY 503
COG4913
COG4913 Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
493-617
2.70e-03
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain]
Cd Length: 1089
Bit Score: 41.44
E-value: 2.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 493 E E T E LRFRQLTMEYQ AL QRAYAL LQE Q vggt LD A EREVKTREQLQAE V QR A QAR I ED LE KA L AEQGQDMKWI ---- E EKQ 568
Cdd:COG4913 620 A E L E EELAEAEERLE AL EAELDA LQE R ---- RE A LQRLAEYSWDEID V AS A ERE I AE LE AE L ERLDASSDDL aale E QLE 695
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1972711173 569 A L YRRNQ EL V E KIKQMET E EA RL RH E VQD A RDQNEL L EF R ILEL E ERE R 617
Cdd:COG4913 696 E L EAELE EL E E ELDELKG E IG RL EK E LEQ A EEELDE L QD R LEAA E DLA R 744
PTZ00121
PTZ00121 MAEBL; Provisional
50-618
3.36e-03
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 41.28
E-value: 3.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 50 E RE K NQEL R QVREHEQHKTAVLLT E LKTKLHEE K MKELQAVR E T ll RQHEA E LLRVIKIKD NE NQ R lqalls ALRDGGPE 129
Cdd:PTZ00121 1192 E LR K AEDA R KAEAARKAEEERKAE E ARKAEDAK K AEAVKKAE E A -- KKDAE E AKKAEEERN NE EI R ------ KFEEARMA 1263
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 130 KVKTVLLSEAK EEA K K GF E VE K VKMQQEIS E L K G A -- K RQVE EA ltlviqad K I KA A E IRSVYHL h QEEITRI KK ECE r E 207
Cdd:PTZ00121 1264 HFARRQAAIKA EEA R K AD E LK K AEEKKKAD E A K K A ee K KKAD EA -------- K K KA E E AKKADEA - KKKAEEA KK KAD - A 1333
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 208 IRRLM EE I K FKDR A VFVLERELGVQ A GH A QRLQLQK E ALD E QLSQVRE A DRHPGSPRRELPH A AGAGDASDHSGSP L DEK 287
Cdd:PTZ00121 1334 AKKKA EE A K KAAE A AKAEAEAAADE A EA A EEKAEAA E KKK E EAKKKAD A AKKKAEEKKKADE A KKKAEEDKKKADE L KKA 1413
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 288 D A RRFQLKI A ELS A IIR K LE D RNALLS EE RNELLKRVRE AE SQY K PLLD K N K RLSR K NE D LSHALRRMEN K LKFVTQENI 367
Cdd:PTZ00121 1414 A A AKKKADE A KKK A EEK K KA D EAKKKA EE AKKADEAKKK AE EAK K AEEA K K K AEEA K KA D EAKKKAEEAK K ADEAKKKAE 1493
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 368 E MRQR A GIIRRPSS ---- LNDLDQSQDEREV D fl KLQIV E QQNLI DE LS K TL E tagy V K SVL E RD K LLRFR K QRK K MA kl 443
Cdd:PTZ00121 1494 E AKKK A DEAKKAAE akkk ADEAKKAEEAKKA D -- EAKKA E EAKKA DE AK K AE E ---- K K KAD E LK K AEELK K AEE K KK -- 1565
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 444 pkpvv V E TFFGYD E EASLESDGSSVSYQTDRTDQTPCTPDDDL E EG M AK EE TE l RFRQLTMEYQA L QR A YALLQEQVGGT 523
Cdd:PTZ00121 1566 ----- A E EAKKAE E DKNMALRKAEEAKKAEEARIEEVMKLYEE E KK M KA EE AK - KAEEAKIKAEE L KK A EEEKKKVEQLK 1639
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 524 LDAER E V K TR E Q L QAEVQRAQARIEDLE K ALA E --- QGQDM K WI EE K ----- Q AL YRRNQ E L -- V E KI K QM E T EE ARLRH 593
Cdd:PTZ00121 1640 KKEAE E K K KA E E L KKAEEENKIKAAEEA K KAE E dkk KAEEA K KA EE D ekkaa E AL KKEAE E A kk A E EL K KK E A EE KKKAE 1719
570 580
....*....|....*....|....*
gi 1972711173 594 E VQD A RDQ N ELLEFRILELE E RER K 618
Cdd:PTZ00121 1720 E LKK A EEE N KIKAEEAKKEA E EDK K 1744
Name
Accession
Description
Interval
E-value
JAKMIP_CC3
pfam16034 JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP ...
426-622
3.00e-86
JAKMIP CC3 domain; This domain is found at the C-terminus of proteins belonging to the JAKMIP family (Janus kinase and microtubule-interacting proteins) and is predicted to be a coiled coil. It interacts with the Janus family kinases Tyk2 and Jak1.
Pssm-ID: 464986 [Multi-domain]
Cd Length: 199
Bit Score: 272.52
E-value: 3.00e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 426 ERDKL L R F RKQR K K MA K LPKP - V VVETFFGYDEEAS LE S DG SS V SY Q TDRTD Q TP C TPD D DL E EG M A K EE T ELRFRQLT M 504
Cdd:pfam16034 1 ERDKL I R A RKQR R K EK K KKLR d M VVETFFGYDEEAS VD S ET SS L SY N TDRTD S TP A TPD E DL D EG V A A EE A ELRFRQLT R 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 505 EYQALQRAYALLQEQ V GGTLDAERE V KTREQLQAE VQ RAQ A RIEDLE K ALA EQ GQD M KW I EEKQAL Y RRNQELVEKI KQ M 584
Cdd:pfam16034 81 EYQALQRAYALLQEQ S GGTLDAERE A KTREQLQAE LR RAQ S RIEDLE S ALA QK GQD S KW V EEKQAL I RRNQELVEKI RI M 160
170 180 190
....*....|....*....|....*....|....*...
gi 1972711173 585 E T EE A RL RH E V QDARDQNELLEFRILELEERER K SPAI 622
Cdd:pfam16034 161 E Q EE G RL KN E I QDARDQNELLEFRILELEERER R SPAI 198
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
27-815
6.26e-09
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 60.07
E-value: 6.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 27 D L R A K L TDIQIE L Q -- QEKSKVSKV E REKNQELRQVR E H E QHKTAVLLT E L K tkl H EE KMK E LQAVR E TLLRQ h EA EL LR 104
Cdd:TIGR02168 217 E L K A E L RELELA L L vl RLEELREEL E ELQEELKEAEE E L E ELTAELQEL E E K --- L EE LRL E VSELE E EIEEL - QK EL YA 292
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 105 VIKIKDNEN Q RL Q A L LSA L RDGGPEKVKTVLLS E AK E EAKKGFEV E KVKMQQEIS ELK GAKRQV E EA L tlviqadkikaa 184
Cdd:TIGR02168 293 LANEISRLE Q QK Q I L RER L ANLERQLEELEAQL E EL E SKLDELAE E LAELEEKLE ELK EELESL E AE L ------------ 360
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 185 eirsvyhlhq EE ITRIKK E C E REIRR L M E EIKFKDRA V FV LE RELGVQAGHAQ RL QLQK E A L DEQLSQVREA drhpgsp R 264
Cdd:TIGR02168 361 ---------- EE LEAELE E L E SRLEE L E E QLETLRSK V AQ LE LQIASLNNEIE RL EARL E R L EDRRERLQQE ------- I 423
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 265 R EL phaagagdasdhs GSP L D E KDARRF Q LKIA EL SAIIRK L EDRNAL L S E ERN EL LKRVR EAE SQYKPLLDKNKR L SRK 344
Cdd:TIGR02168 424 E EL ------------- LKK L E E AELKEL Q AELE EL EEELEE L QEELER L E E ALE EL REELE EAE QALDAAERELAQ L QAR 490
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 345 NED L SHALRRM E NKLKF V TQENIEMRQRA GI IRRP S S L NDL D q SQD E REVD flklq IVEQQN L IDELSKT L ET A GYVKSV 424
Cdd:TIGR02168 491 LDS L ERLQENL E GFSEG V KALLKNQSGLS GI LGVL S E L ISV D - EGY E AAIE ----- AALGGR L QAVVVEN L NA A KKAIAF 564
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 425 L ERDK L L R frkqrkk MAK LP KPVVVE T FFGYDEEAS L ESDGSSVSYQT D RTDQT P ------------ CTPD DDL EEGMA - 491
Cdd:TIGR02168 565 L KQNE L G R ------- VTF LP LDSIKG T EIQGNDREI L KNIEGFLGVAK D LVKFD P klrkalsyllgg VLVV DDL DNALE l 637
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 492 KEETELRF R QL T MEYQALQRAYALLQ --- EQVGGT L DAE RE V ktr E Q L QAEVQRAQAR I ED LEKALAE --- QGQDMK wi E 565
Cdd:TIGR02168 638 AKKLRPGY R IV T LDGDLVRPGGVITG gsa KTNSSI L ERR RE I --- E E L EEKIEELEEK I AE LEKALAE lrk ELEELE -- E 712
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 566 E KQA L YRRNQ EL VEK I KQMETEE ARL RH EV QDARDQNEL L EFRIL ELE ERERKSPAI sfhhtpf VDGKSPLQVYC EAE gv 645
Cdd:TIGR02168 713 E LEQ L RKELE EL SRQ I SALRKDL ARL EA EV EQLEERIAQ L SKELT ELE AEIEELEER ------- LEEAEEELAEA EAE -- 783
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 646 tdiv VA EL MKKLDI L GDNANLTN E EQV vvi QA R TV LTL AEKWLQQIE E TEAA L Q R KMVDL E SEK E LFSK Q KGY L D E ELDY 725
Cdd:TIGR02168 784 ---- IE EL EAQIEQ L KEELKALR E ALD --- EL R AE LTL LNEEAANLR E RLES L E R RIAAT E RRL E DLEE Q IEE L S E DIES 856
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 726 RKQALDQANKH I L ELE AM L YDA L QQE A GAKV A EL L SEE E R E K L KVAVEQWKRQVMSEL RE RDA qi LRE RMEL L Q L AQQRI 805
Cdd:TIGR02168 857 LAAEIEELEEL I E ELE SE L EAL L NER A SLEE A LA L LRS E L E E L SEELRELESKRSELR RE LEE -- LRE KLAQ L E L RLEGL 934
810
....*....|
gi 1972711173 806 KELEERIEAQ 815
Cdd:TIGR02168 935 EVRIDNLQER 944
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
492-818
3.15e-08
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 57.64
E-value: 3.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 492 K E ET EL RFRQ L TMEYQA L QRAYAL L QEQVG - GTLDA E REVKTREQ L Q AE VQRAQARI E D LE KA L A E - Q GQDMKWIE E KQA 569
Cdd:COG1196 220 E E LK EL EAEL L LLKLRE L EAELEE L EAELE e LEAEL E ELEAELAE L E AE LEELRLEL E E LE LE L E E a Q AEEYELLA E LAR 299
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 570 L YRRNQE L V E KIKQM E TEEAR L RH E VQDARDQN E L LE FRIL ELEE RE rkspaisfhhtpfvdgksplqvyceaegvtdiv 649
Cdd:COG1196 300 L EQDIAR L E E RRREL E ERLEE L EE E LAELEEEL E E LE EELE ELEE EL --------------------------------- 346
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 650 v A E LMKK L D ilgdnanltn E EQVVVIQ A RTV L TL AE KW L QQI EE TEAA L QRKMVDLESEKELFSK Q KGY L D E ELDYRKQA 729
Cdd:COG1196 347 - E E AEEE L E ---------- E AEAELAE A EEA L LE AE AE L AEA EE ELEE L AEELLEALRAAAELAA Q LEE L E E AEEALLER 415
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 730 L DQANKHIL ELE AM L YDALQQ E AGAKV A ELLSE EE REK L KVAV E Q w KRQVMS EL R E RD A QILRERM ELL QLAQQRIKE L E 809
Cdd:COG1196 416 L ERLEEELE ELE EA L AELEEE E EEEEE A LEEAA EE EAE L EEEE E A - LLELLA EL L E EA A LLEAALA ELL EELAEAAAR L L 494
....*....
gi 1972711173 810 ERI EA QKRQ 818
Cdd:COG1196 495 LLL EA EADY 503
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
26-616
8.31e-08
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 56.10
E-value: 8.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 26 ED L R A K L TDIQIELQQEKSKVSKV E R E KNQELRQVR E H E QHKTAVL L T EL KTK L H E EK m K EL QAVRET l LRQHE AEL L R V 105
Cdd:COG1196 223 KE L E A E L LLLKLRELEAELEELEA E L E ELEAELEEL E A E LAELEAE L E EL RLE L E E LE - L EL EEAQAE - EYELL AEL A R L 300
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 106 IKIKDNENQ R LQA L LSA L rdggpekvktvlls E AK EE AKKGF E V E KVKMQQ E IS EL KGAKRQV EE A L TLVIQADKIKAAE 185
Cdd:COG1196 301 EQDIARLEE R RRE L EER L -------------- E EL EE ELAEL E E E LEELEE E LE EL EEELEEA EE E L EEAEAELAEAEEA 366
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 186 irsvyhlh QE E ITRIKK E C E R E IRR L M EE IKFKD RA VFV L ERE L GVQAGHAQR L QLQK E A L D E Q L SQVR EA DRH pgsprr 265
Cdd:COG1196 367 -------- LL E AEAELA E A E E E LEE L A EE LLEAL RA AAE L AAQ L EELEEAEEA L LERL E R L E E E L EELE EA LAE ------ 432
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 266 elphaagagdasdhsgspl D E KDARRFQLKIA E LSAIIRK LE DRNAL L S E ERN ELL KRVREA E SQYKP LL DKNKRLSRKN 345
Cdd:COG1196 433 ------------------- L E EEEEEEEEALE E AAEEEAE LE EEEEA L L E LLA ELL EEAALL E AALAE LL EELAEAAARL 493
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 346 ED L SH A LRRM E NK L KF V T qeni EMRQR AG IIRRPSSLND L DQSQDER E VDFLK - L QIVE Q QNLIDELSKTLETAG Y V K S - 423
Cdd:COG1196 494 LL L LE A EADY E GF L EG V K ---- AALLL AG LRGLAGAVAV L IGVEAAY E AALEA a L AAAL Q NIVVEDDEVAAAAIE Y L K A a 569
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 424 VLE R DKL L RFR K Q R KKM A KLPKPVVVETFFGY D EE AS LESDGSSVS Y Q - T D RTDQTPCTPDDDLEEGMAKEETEL R F R QL 502
Cdd:COG1196 570 KAG R ATF L PLD K I R ARA A LAAALARGAIGAAV D LV AS DLREADARY Y V l G D TLLGRTLVAARLEAALRRAVTLAG R L R EV 649
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 503 T M E YQALQRAYA L LQEQVGGT L D A ER E VKTREQLQ AE VQRAQARIEDLEKALA E QGQDMKWIE E KQA L YRRNQ E LVEKIK 582
Cdd:COG1196 650 T L E GEGGSAGGS L TGGSRREL L A A LL E AEAELEEL AE RLAEEELELEEALLAE E EEERELAEA E EER L EEELE E EALEEQ 729
570 580 590
....*....|....*....|....*....|....
gi 1972711173 583 QMETE E AR L RHEVQDARDQN E LLEFRIL E LEER E 616
Cdd:COG1196 730 LEAER E EL L EELLEEEELLE E EALEELP E PPDL E 763
SMC_prok_A
TIGR02169 chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
45-820
2.97e-07
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain]
Cd Length: 1164
Bit Score: 54.30
E-value: 2.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 45 KVSKVER EK N Q E L RQV R EHEQHKTAVL lt E L KTKLH E EKMK EL QAVR E T L L RQ H EA e LL R VIKIKDN E NQR L QALL S A L R 124
Cdd:TIGR02169 188 RLDLIID EK R Q Q L ERL R REREKAERYQ -- A L LKEKR E YEGY EL LKEK E A L E RQ K EA - IE R QLASLEE E LEK L TEEI S E L E 264
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 125 DGGP E KVK tv LL S E AKEEA K KGF E V E KVKMQQE I S EL KG ---- AK R QVE E ALTLVIQ A DK i KA A EIRSVYHLHQE EI TRI 200
Cdd:TIGR02169 265 KRLE E IEQ -- LL E E LNKKI K DLG E E E QLRVKEK I G EL EA eias LE R SIA E KERELED A EE - RL A KLEAEIDKLLA EI EEL 341
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 201 KK E C E R E IR R --- L M EE IKFKDRAVFV L ER EL GVQAGHAQRLQLQKEALD E Q L SQV - RE ADRHPGSPR R EL phaagagda 276
Cdd:TIGR02169 342 ER E I E E E RK R rdk L T EE YAELKEELED L RA EL EEVDKEFAETRDELKDYR E K L EKL k RE INELKRELD R LQ --------- 412
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 277 sdhsgsplde KDAR R FQLKI A E L S A I I RKL E DRNAL L S EE RNELLKRVREA E SQYKP L LDKNKRLSRKNE DL SHALR R M E 356
Cdd:TIGR02169 413 ---------- EELQ R LSEEL A D L N A A I AGI E AKINE L E EE KEDKALEIKKQ E WKLEQ L AADLSKYEQELY DL KEEYD R V E 482
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 357 NK L KFVTQ E NI E MRQR A GIIRRPSSLNDLDQSQDEREVDFLKLQIVEQQNLIDELSKTL E T A G ------- Y V KSVLERDK 429
Cdd:TIGR02169 483 KE L SKLQR E LA E AEAQ A RASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAI E V A A gnrlnnv V V EDDAVAKE 562
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 430 LLRFR K Q RK ---------- KM AKLPKPVVVETFF G YDEE A ---- SLESDGSSVSYQTDRTDQTP ctpd D D L E EG mak EET 495
Cdd:TIGR02169 563 AIELL K R RK agratflpln KM RDERRDLSILSED G VIGF A vdlv EFDPKYEPAFKYVFGDTLVV ---- E D I E AA --- RRL 635
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 496 ELRF R QL T M E YQALQRAY A L lqeq V GG TLDAEREVKTREQLQ AE V QR AQA R I E D L EKA L AEQGQDMKW IE ek QA L YRRN Q 575
Cdd:TIGR02169 636 MGKY R MV T L E GELFEKSG A M ---- T GG SRAPRGGILFSRSEP AE L QR LRE R L E G L KRE L SSLQSELRR IE -- NR L DELS Q 709
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 576 EL VEKIKQMETE E ARLRHEV Q DARDQN E L LE FRILE L EER E RKSPAI sfhhtpfvdg KS P L Q vyc E A E GVTDIVVAE L M K 655
Cdd:TIGR02169 710 EL SDASRKIGEI E KEIEQLE Q EEEKLK E R LE ELEED L SSL E QEIENV ---------- KS E L K --- E L E ARIEELEED L H K 776
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 656 KLDI L G D NANLTNEEQVVV IQA R tv L TLA E KWLQQ IE ETEAALQR K MVD L ES EKE LFS K QKGY L D E ELDYR K QALDQAN K 735
Cdd:TIGR02169 777 LEEA L N D LEARLSHSRIPE IQA E -- L SKL E EEVSR IE ARLREIEQ K LNR L TL EKE YLE K EIQE L Q E QRIDL K EQIKSIE K 854
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 736 H I LE L EAMLYDALQQEAGAKV A ELLS E EEREK LK VAVEQWKR Q v MS EL RER daqi LR E RMELLQLAQQ R IK EL EERI EA Q 815
Cdd:TIGR02169 855 E I EN L NGKKEELEEELEELEA A LRDL E SRLGD LK KERDELEA Q - LR EL ERK ---- IE E LEAQIEKKRK R LS EL KAKL EA L 929
....*
gi 1972711173 816 KRQIK 820
Cdd:TIGR02169 930 EEELS 934
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
491-818
2.43e-05
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 48.01
E-value: 2.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 491 AK EE TE L RFRQ L TM E YQAL Q RAYAL L QEQVGG -------- TLDAEREVKTR E Q L QA E VQRAQARI E D LE KA L A E QGQD mk 562
Cdd:COG1196 268 EL EE LR L ELEE L EL E LEEA Q AEEYE L LAELAR leqdiarl EERRRELEERL E E L EE E LAELEEEL E E LE EE L E E LEEE -- 345
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 563 w I EE KQALYRRNQELVEKIKQMET E EARLRH E VQDARDQNELLEFRI L ELEERERKSPA isfhhtpfvdgksplqvyc E A 642
Cdd:COG1196 346 - L EE AEEELEEAEAELAEAEEALL E AEAELA E AEEELEELAEELLEA L RAAAELAAQLE ------------------- E L 405
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 643 E GVTDIVVAE L MKKLDI L GDNANLTN E EQVVVIQARTV L TL A EKWLQQI EE T E A AL QRKMVD L ES E KE L fskqkgy L DEE 722
Cdd:COG1196 406 E EAEEALLER L ERLEEE L EELEEALA E LEEEEEEEEEA L EE A AEEEAEL EE E E E AL LELLAE L LE E AA L ------- L EAA 478
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 723 L DYRKQA L DQ A NKHI L E L EAMLY D ALQQEA G A K V A E LL SEEEREKLK VAV EQWK rqvms E LRERD A QILRERME L LQLAQ 802
Cdd:COG1196 479 L AELLEE L AE A AARL L L L LEAEA D YEGFLE G V K A A L LL AGLRGLAGA VAV LIGV ----- E AAYEA A LEAALAAA L QNIVV 553
330
....*....|....*.
gi 1972711173 803 QRIKELEER IE AQ K RQ 818
Cdd:COG1196 554 EDDEVAAAA IE YL K AA 569
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
9-592
1.15e-04
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 46.08
E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 9 RAKGDKAEA L AALQ A AN E DL R AK L TDIQI EL QQ E K skvskverekn Q EL RQVR E HEQHKTAV L LT EL KTK lh EE KMK E LQ 88
Cdd:COG1196 291 YELLAELAR L EQDI A RL E ER R RE L EERLE EL EE E L ----------- A EL EEEL E ELEEELEE L EE EL EEA -- EE ELE E AE 357
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 89 A VRETLLRQHEAELLRVIKIKDNENQRLQA LL S ALR dggp EKVKTVLLS E AK EEA KKGFEVEKVKMQQ E IS EL KG A KRQV 168
Cdd:COG1196 358 A ELAEAEEALLEAEAELAEAEEELEELAEE LL E ALR ---- AAAELAAQL E EL EEA EEALLERLERLEE E LE EL EE A LAEL 433
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 169 EE ALTLVIQ A DKIK A A E irsvyhlh QE E ITRIKKECEREIRR L M EE IKFKDR A VFV L ER EL GVQ A GHAQR L QLQKEALDE 248
Cdd:COG1196 434 EE EEEEEEE A LEEA A E E -------- EA E LEEEEEALLELLAE L L EE AALLEA A LAE L LE EL AEA A ARLLL L LEAEADYEG 505
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 249 Q L SQ V RE A DRHP G SPRRELPH A AGA G D asdhsgspldek D A RRFQLKI A E L S A IIRKLEDRNALLSEERN E L LK RVREAE 328
Cdd:COG1196 506 F L EG V KA A LLLA G LRGLAGAV A VLI G V ------------ E A AYEAALE A A L A A ALQNIVVEDDEVAAAAI E Y LK AAKAGR 573
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 329 SQYK PL LDKNK R LSRKNEDLSH A LRRMENKLKFVTQ E NIEMRQRA G IIRRPSS L NDLDQSQDE R EVDF L KLQIV E QQNLI 408
Cdd:COG1196 574 ATFL PL DKIRA R AALAAALARG A IGAAVDLVASDLR E ADARYYVL G DTLLGRT L VAARLEAAL R RAVT L AGRLR E VTLEG 653
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 409 DEL S KTLETA G YVKSV L ERDK L LRFRKQRKKMAK L pkpvvvetffg YD EE AS LE SDGSSVSYQTDRTDQ tpctp DDDLEE 488
Cdd:COG1196 654 EGG S AGGSLT G GSRRE L LAAL L EAEAELEELAER L ----------- AE EE LE LE EALLAEEEEERELAE ----- AEEERL 717
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 489 GMAK EE TE L RFRQLTMEYQA L QRAYALLQEQVGGT L DAER E VKTR E Q L QA E VQ R AQAR IE D L EK -- A LA eqgqdmkw IEE 566
Cdd:COG1196 718 EEEL EE EA L EEQLEAEREEL L EELLEEEELLEEEA L EELP E PPDL E E L ER E LE R LERE IE A L GP vn L LA -------- IEE 789
570 580
....*....|....*....|....*.
gi 1972711173 567 KQA L YR R NQE L V E KIKQM E TEEAR L R 592
Cdd:COG1196 790 YEE L EE R YDF L S E QREDL E EARET L E 815
EnvC
COG4942 Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
26-256
1.19e-03
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain]
Cd Length: 377
Bit Score: 42.06
E-value: 1.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 26 EDLR A K L TDI Q I E LQQEKSKVSKVER E KNQE L R Q VREH E Q hkt AVLLTELKTKLH E EKMKE L Q A V retl L RQH E A E LLRV 105
Cdd:COG4942 23 AEAE A E L EQL Q Q E IAELEKELAALKK E EKAL L K Q LAAL E R --- RIAALARRIRAL E QELAA L E A E ---- L AEL E K E IAEL 95
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 106 IKIKDNENQR L QA LL S AL - R D G GPEKVKTV L LS E AKEE A kkgfevek V KMQ Q EISE L KG A K R QVE E A L TLVIQADKIKA A 184
Cdd:COG4942 96 RAELEAQKEE L AE LL R AL y R L G RQPPLALL L SP E DFLD A -------- V RRL Q YLKY L AP A R R EQA E E L RADLAELAALR A 167
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1972711173 185 E IRS vyhl HQE E ITRIKK E C E R E IRR L MEEIKFKDRAVFV LE R EL GVQ A GHAQR LQ LQK E A L DEQLSQVREA 256
Cdd:COG4942 168 E LEA ---- ERA E LEALLA E L E E E RAA L EALKAERQKLLAR LE K EL AEL A AELAE LQ QEA E E L EALIARLEAE 235
SMC_prok_B
TIGR02168 chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
492-816
1.27e-03
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain]
Cd Length: 1179
Bit Score: 42.74
E-value: 1.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 492 K E ET EL RFRQ L TMEYQA L QRAYAL LQE QV ggtlda EREVKTR E Q L Q AE V Q RAQARI E D L EKALA E QG qdmkwi EE KQA L Y 571
Cdd:TIGR02168 220 A E LR EL ELAL L VLRLEE L REELEE LQE EL ------ KEAEEEL E E L T AE L Q ELEEKL E E L RLEVS E LE ------ EE IEE L Q 287
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 572 RRNQE L VEK I KQM E TEEAR LR HEVQDARD Q N E L LE FRIL ELE ERERKSPAIS fhh TPFVDGKSP L QVYC E AE gvtdiv V A 651
Cdd:TIGR02168 288 KELYA L ANE I SRL E QQKQI LR ERLANLER Q L E E LE AQLE ELE SKLDELAEEL --- AELEEKLEE L KEEL E SL ------ E A 358
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 652 EL MKKLDI L GDNANLTN E EQVVVIQA R TVLTLA E kwl Q QI EETEAALQ R kmvd LE SEK E LFSKQKGY L DE E LDYRKQA L D 731
Cdd:TIGR02168 359 EL EELEAE L EELESRLE E LEEQLETL R SKVAQL E --- L QI ASLNNEIE R ---- LE ARL E RLEDRRER L QQ E IEELLKK L E 431
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 732 Q A NKHI L EL E AMLYDALQQ E AGAKVAE L LSEE E REKLKVAVEQWKRQ vmse LR ER DAQI L RE R MEL L QLA Q QRIKELE E R 811
Cdd:TIGR02168 432 E A ELKE L QA E LEELEEELE E LQEELER L EEAL E ELREELEEAEQALD ---- AA ER ELAQ L QA R LDS L ERL Q ENLEGFS E G 507
....*
gi 1972711173 812 IE A QK 816
Cdd:TIGR02168 508 VK A LL 512
Smc
COG1196 Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
525-818
1.37e-03
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain]
Cd Length: 983
Bit Score: 42.23
E-value: 1.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 525 D AER E VKTR - E Q L QAEVQR A ------ QARIED LE KA L A eq GQDMKWI E EKQALYRRN - Q EL VEKIKQM E T E E A R L RH E VQ 596
Cdd:COG1196 193 D ILG E LERQ l E P L ERQAEK A eryrel KEELKE LE AE L L -- LLKLREL E AELEELEAE l E EL EAELEEL E A E L A E L EA E LE 270
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 597 DA R DQN E L LE FRIL E LEER E RKS paisfhhtpfvdgksplqvyceaegvtdivvaelmkkldilgd N A N L TNE EQ VVVIQ 676
Cdd:COG1196 271 EL R LEL E E LE LELE E AQAE E YEL ------------------------------------------- L A E L ARL EQ DIARL 307
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 677 ARTVLT L A E K w L QQI EE TE A A L QRKMVD LE S E K E LFSKQKGYLD EEL DYRKQA L DQ A NKHI LE L EA M L YD A LQQEAGAKV 756
Cdd:COG1196 308 EERRRE L E E R - L EEL EE EL A E L EEELEE LE E E L E ELEEELEEAE EEL EEAEAE L AE A EEAL LE A EA E L AE A EEELEELAE 386
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1972711173 757 AE L LSEEEREK L KVAV E QWKRQVMSE L RERDAQILRERMELLQ LA QQRIK E L EE RIEAQKRQ 818
Cdd:COG1196 387 EL L EALRAAAE L AAQL E ELEEAEEAL L ERLERLEEELEELEEA LA ELEEE E E EE EEALEEAA 448
YhaN
COG4717 Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
485-819
1.84e-03
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain]
Cd Length: 641
Bit Score: 41.68
E-value: 1.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 485 D L E E GMA K E E TE L RFRQ L TM E YQ AL QRAY A L L Q E QVG gtl DA E REVKTREQ L QA E VQRAQ A RIED L EKA L A E QGQDMKWI 564
Cdd:COG4717 113 E L R E ELE K L E KL L QLLP L YQ E LE AL EAEL A E L P E RLE --- EL E ERLEELRE L EE E LEELE A ELAE L QEE L E E LLEQLSLA 189
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 565 E E KQA -- L YRRNQ EL VEKIKQM E T E EARLRH E VQDARDQN E L LE FRILELEER ER KS ------ PAISFHHTPFVD G K S P L 636
Cdd:COG4717 190 T E EEL qd L AEELE EL QQRLAEL E E E LEEAQE E LEELEEEL E Q LE NELEAAALE ER LK earlll LIAAALLALLGL G G S L L 269
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 637 QVYCEAE GV TDI V VAE lmkkld ILGDNAN L TN E EQVVVIQ A RTVLT L AEKWLQQI EE T E AA L QRKMVDLESEK E LFSKQK 716
Cdd:COG4717 270 SLILTIA GV LFL V LGL ------ LALLFLL L AR E KASLGKE A EELQA L PALEELEE EE L E EL L AALGLPPDLSP E ELLELL 343
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 717 GYLD E ELDYRKQ A LDQANKHI LE LEAMLYD AL QQ EAG AKVA E L L SE ----- EE REK LK VAV E QWKR Q VMSE L R E R ---- D 787
Cdd:COG4717 344 DRIE E LQELLRE A EELEEELQ LE ELEQEIA AL LA EAG VEDE E E L RA aleqa EE YQE LK EEL E ELEE Q LEEL L G E L eell E 423
330 340 350
....*....|....*....|....*....|..
gi 1972711173 788 A QILR E RM E L L QLAQQRIK ELEE RI E AQKRQI 819
Cdd:COG4717 424 A LDEE E LE E E L EELEEELE ELEE EL E ELREEL 455
COG4913
COG4913 Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
493-617
2.70e-03
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain]
Cd Length: 1089
Bit Score: 41.44
E-value: 2.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 493 E E T E LRFRQLTMEYQ AL QRAYAL LQE Q vggt LD A EREVKTREQLQAE V QR A QAR I ED LE KA L AEQGQDMKWI ---- E EKQ 568
Cdd:COG4913 620 A E L E EELAEAEERLE AL EAELDA LQE R ---- RE A LQRLAEYSWDEID V AS A ERE I AE LE AE L ERLDASSDDL aale E QLE 695
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1972711173 569 A L YRRNQ EL V E KIKQMET E EA RL RH E VQD A RDQNEL L EF R ILEL E ERE R 617
Cdd:COG4913 696 E L EAELE EL E E ELDELKG E IG RL EK E LEQ A EEELDE L QD R LEAA E DLA R 744
PTZ00121
PTZ00121 MAEBL; Provisional
50-618
3.36e-03
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain]
Cd Length: 2084
Bit Score: 41.28
E-value: 3.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 50 E RE K NQEL R QVREHEQHKTAVLLT E LKTKLHEE K MKELQAVR E T ll RQHEA E LLRVIKIKD NE NQ R lqalls ALRDGGPE 129
Cdd:PTZ00121 1192 E LR K AEDA R KAEAARKAEEERKAE E ARKAEDAK K AEAVKKAE E A -- KKDAE E AKKAEEERN NE EI R ------ KFEEARMA 1263
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 130 KVKTVLLSEAK EEA K K GF E VE K VKMQQEIS E L K G A -- K RQVE EA ltlviqad K I KA A E IRSVYHL h QEEITRI KK ECE r E 207
Cdd:PTZ00121 1264 HFARRQAAIKA EEA R K AD E LK K AEEKKKAD E A K K A ee K KKAD EA -------- K K KA E E AKKADEA - KKKAEEA KK KAD - A 1333
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 208 IRRLM EE I K FKDR A VFVLERELGVQ A GH A QRLQLQK E ALD E QLSQVRE A DRHPGSPRRELPH A AGAGDASDHSGSP L DEK 287
Cdd:PTZ00121 1334 AKKKA EE A K KAAE A AKAEAEAAADE A EA A EEKAEAA E KKK E EAKKKAD A AKKKAEEKKKADE A KKKAEEDKKKADE L KKA 1413
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 288 D A RRFQLKI A ELS A IIR K LE D RNALLS EE RNELLKRVRE AE SQY K PLLD K N K RLSR K NE D LSHALRRMEN K LKFVTQENI 367
Cdd:PTZ00121 1414 A A AKKKADE A KKK A EEK K KA D EAKKKA EE AKKADEAKKK AE EAK K AEEA K K K AEEA K KA D EAKKKAEEAK K ADEAKKKAE 1493
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 368 E MRQR A GIIRRPSS ---- LNDLDQSQDEREV D fl KLQIV E QQNLI DE LS K TL E tagy V K SVL E RD K LLRFR K QRK K MA kl 443
Cdd:PTZ00121 1494 E AKKK A DEAKKAAE akkk ADEAKKAEEAKKA D -- EAKKA E EAKKA DE AK K AE E ---- K K KAD E LK K AEELK K AEE K KK -- 1565
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 444 pkpvv V E TFFGYD E EASLESDGSSVSYQTDRTDQTPCTPDDDL E EG M AK EE TE l RFRQLTMEYQA L QR A YALLQEQVGGT 523
Cdd:PTZ00121 1566 ----- A E EAKKAE E DKNMALRKAEEAKKAEEARIEEVMKLYEE E KK M KA EE AK - KAEEAKIKAEE L KK A EEEKKKVEQLK 1639
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 524 LDAER E V K TR E Q L QAEVQRAQARIEDLE K ALA E --- QGQDM K WI EE K ----- Q AL YRRNQ E L -- V E KI K QM E T EE ARLRH 593
Cdd:PTZ00121 1640 KKEAE E K K KA E E L KKAEEENKIKAAEEA K KAE E dkk KAEEA K KA EE D ekkaa E AL KKEAE E A kk A E EL K KK E A EE KKKAE 1719
570 580
....*....|....*....|....*
gi 1972711173 594 E VQD A RDQ N ELLEFRILELE E RER K 618
Cdd:PTZ00121 1720 E LKK A EEE N KIKAEEAKKEA E EDK K 1744
COG2433
COG2433 Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
525-614
3.84e-03
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain]
Cd Length: 644
Bit Score: 41.00
E-value: 3.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972711173 525 DA E REVKTR E -- Q L QAE V Q R AQ A RI E D LE KA L A E QGQDMKWI E EKQALY R RNQELV ---- EK I KQMET E EA RL RH E VQDA 598
Cdd:COG2433 405 ER E LTEEEE E ir R L EEQ V E R LE A EV E E LE AE L E E KDERIERL E RELSEA R SEERRE irkd RE I SRLDR E IE RL ER E LEEE 484
90
....*....|....*.
gi 1972711173 599 R DQN E L L EFRILE L E E 614
Cdd:COG2433 485 R ERI E E L KRKLER L K E 500
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
