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Full Results
solute carrier family 12 member 1 isoform B [Homo sapiens]
Protein Classification
solute carrier family 12 protein ( domain architecture ID 11489985 )
solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis, or human kidney-specific Na-K-Cl symporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation
List of domain hits
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
104-1099
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1480.34
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 104 NT M DAVP K IE Y YRN TGSIS GPK V NRPSL L E I H EQ L A K N V AVTPSS AD RVA NG D G IPGD E Q AE N ---- KE DDQ AG V VKFGW 179
Cdd:TIGR00930 1 NT V DAVP R IE H YRN SEGQG GPK R NRPSL E E L H DL L D K V V SLLGPL AD YTN NG Q G MKEH E E AE D aegt KE KPP AG A VKFGW 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 180 V K GVLV R C M LNIWGV M LF I RLSWIVG E AGIGL GVI II G L AVT VT G ITGLS T SAIATNG C V R GGGAYYLISRSLGPEFGGS 259
Cdd:TIGR00930 81 V M GVLV P C L LNIWGV I LF L RLSWIVG Q AGIGL SLL II L L CCC VT T ITGLS M SAIATNG V V K GGGAYYLISRSLGPEFGGS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 260 IGLIFAFANAVAVAMYVVGFAETV V DLL K E SD S - M MVDP T NDIRI I G SI TVV I LLGIS V AGMEWE A KAQV IL LVI L L IA I 338
Cdd:TIGR00930 161 IGLIFAFANAVAVAMYVVGFAETV L DLL R E NG S k I MVDP I NDIRI Y G TV TVV V LLGIS F AGMEWE N KAQV LF LVI V L LS I 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 339 A N F F I GT V IP SNN e K KSR GFF NYQAS IF A ENF G P RFTKG EG - FFS V F A IFFP AA TGILAGANISGDL E DPQ D AIP R GT M L 417
Cdd:TIGR00930 241 L N I F V GT I IP AFD - K PAK GFF GLGNE IF S ENF I P GIPGP EG g FFS L F G IFFP SV TGILAGANISGDL K DPQ K AIP K GT L L 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 418 AI FI TTV A YLG VAICV GACVVRDATG NM NDT IIS gmn CNG SAAC glgyd FS R C R H EP C Q YGLMNN F QVMS M VS G F G PLIT 497
Cdd:TIGR00930 320 AI LT TTV V YLG SVVLF GACVVRDATG DK NDT LVT --- NCT SAAC ----- FS E C A H NT C S YGLMNN L QVMS L VS P F P PLIT 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 498 AGIFSATLSSALASLVSAP KV FQALCKDNIY KA LQFF A KGYGKN N EPLR G Y I LT FL IA MA FILIAELNTIAPIISNFFLA 577
Cdd:TIGR00930 392 AGIFSATLSSALASLVSAP RL FQALCKDNIY PF LQFF G KGYGKN G EPLR A Y L LT AF IA EG FILIAELNTIAPIISNFFLA 471
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 578 SYALINFSCFHAS YAK SPGWRP AYGI Y NM W V SL F GA V LCCA V MF V I N WWAA VITY VI EF FLY V YVT C KKPDVNWGSSTQA 657
Cdd:TIGR00930 472 SYALINFSCFHAS LLR SPGWRP RFKY Y HW W L SL L GA S LCCA I MF L I S WWAA LVAM VI AL FLY K YVT Y KKPDVNWGSSTQA 551
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 658 LSY VS AL DNA L E L TT VEDHVKN F RPQC I VLTG G P MT RPALLD ITHA FTK NS GL C IC CE V FV GPR KL CVKE MNSGM AK K Q A 737
Cdd:TIGR00930 552 LSY SL AL YSL L R L EE VEDHVKN W RPQC L VLTG P P VC RPALLD FASQ FTK GK GL M IC GS V IQ GPR LE CVKE AQAAE AK I Q T 631
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 738 WL I KNK I KAFYA A V A AD CF R D GVR S L L QASGLGRMKPNTLV I GYKK N WR K A PLTEI E N Y V GIIHDAFD FEIG VV I VR I S Q 817
Cdd:TIGR00930 632 WL E KNK V KAFYA V V V AD DL R E GVR H L I QASGLGRMKPNTLV M GYKK D WR Q A EPRAW E T Y I GIIHDAFD AHLA VV V VR N S E 711
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 818 G FD IS q VLQVQEELE rleqerlaleatikd N E C E E E S ggirglfkkagklnitkt TPKK DG S I N T SQS MH vgefnqkl V E 897
Cdd:TIGR00930 712 G LP IS - VLQVQEELE --------------- N D C S E D S ------------------ IELN DG K I S T QPD MH -------- L E 749
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 898 ASTQF K KKQ E KGTIDVWWL F DDGGLTLL I PY I LT LR K K WK D CK L RI Y VG G - K IN R I E E EK IV MA S LL S KFRI KFAD I HII 976
Cdd:TIGR00930 750 ASTQF Q KKQ G KGTIDVWWL V DDGGLTLL L PY L LT TK K V WK K CK I RI F VG A q K DD R S E Q EK KD MA T LL Y KFRI DAEV I VVL 829
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 977 G DIN IR P NK ES WKV FEEMI E P Y RLH ESC KD LTTAE - K LKRET PWKITDAEL EAVKE KSYRQVRLNELL Q E H SR A A N L I VL 1055
Cdd:TIGR00930 830 M DIN AK P QT ES MEA FEEMI R P F RLH KTE KD REAKD p K MTWTK PWKITDAEL QSNVR KSYRQVRLNELL L E Y SR D A A L V VL 909
970 980 990 1000
....*....|....*....|....*....|....*....|....
gi 1847688283 1056 SLPV A RKGSI S D L LYMAWLE I L TKN LPPVLLVRGNH K NVLTFYS 1099
Cdd:TIGR00930 910 SLPV P RKGSI P D E LYMAWLE V L SED LPPVLLVRGNH R NVLTFYS 953
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
104-1099
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1480.34
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 104 NT M DAVP K IE Y YRN TGSIS GPK V NRPSL L E I H EQ L A K N V AVTPSS AD RVA NG D G IPGD E Q AE N ---- KE DDQ AG V VKFGW 179
Cdd:TIGR00930 1 NT V DAVP R IE H YRN SEGQG GPK R NRPSL E E L H DL L D K V V SLLGPL AD YTN NG Q G MKEH E E AE D aegt KE KPP AG A VKFGW 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 180 V K GVLV R C M LNIWGV M LF I RLSWIVG E AGIGL GVI II G L AVT VT G ITGLS T SAIATNG C V R GGGAYYLISRSLGPEFGGS 259
Cdd:TIGR00930 81 V M GVLV P C L LNIWGV I LF L RLSWIVG Q AGIGL SLL II L L CCC VT T ITGLS M SAIATNG V V K GGGAYYLISRSLGPEFGGS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 260 IGLIFAFANAVAVAMYVVGFAETV V DLL K E SD S - M MVDP T NDIRI I G SI TVV I LLGIS V AGMEWE A KAQV IL LVI L L IA I 338
Cdd:TIGR00930 161 IGLIFAFANAVAVAMYVVGFAETV L DLL R E NG S k I MVDP I NDIRI Y G TV TVV V LLGIS F AGMEWE N KAQV LF LVI V L LS I 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 339 A N F F I GT V IP SNN e K KSR GFF NYQAS IF A ENF G P RFTKG EG - FFS V F A IFFP AA TGILAGANISGDL E DPQ D AIP R GT M L 417
Cdd:TIGR00930 241 L N I F V GT I IP AFD - K PAK GFF GLGNE IF S ENF I P GIPGP EG g FFS L F G IFFP SV TGILAGANISGDL K DPQ K AIP K GT L L 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 418 AI FI TTV A YLG VAICV GACVVRDATG NM NDT IIS gmn CNG SAAC glgyd FS R C R H EP C Q YGLMNN F QVMS M VS G F G PLIT 497
Cdd:TIGR00930 320 AI LT TTV V YLG SVVLF GACVVRDATG DK NDT LVT --- NCT SAAC ----- FS E C A H NT C S YGLMNN L QVMS L VS P F P PLIT 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 498 AGIFSATLSSALASLVSAP KV FQALCKDNIY KA LQFF A KGYGKN N EPLR G Y I LT FL IA MA FILIAELNTIAPIISNFFLA 577
Cdd:TIGR00930 392 AGIFSATLSSALASLVSAP RL FQALCKDNIY PF LQFF G KGYGKN G EPLR A Y L LT AF IA EG FILIAELNTIAPIISNFFLA 471
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 578 SYALINFSCFHAS YAK SPGWRP AYGI Y NM W V SL F GA V LCCA V MF V I N WWAA VITY VI EF FLY V YVT C KKPDVNWGSSTQA 657
Cdd:TIGR00930 472 SYALINFSCFHAS LLR SPGWRP RFKY Y HW W L SL L GA S LCCA I MF L I S WWAA LVAM VI AL FLY K YVT Y KKPDVNWGSSTQA 551
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 658 LSY VS AL DNA L E L TT VEDHVKN F RPQC I VLTG G P MT RPALLD ITHA FTK NS GL C IC CE V FV GPR KL CVKE MNSGM AK K Q A 737
Cdd:TIGR00930 552 LSY SL AL YSL L R L EE VEDHVKN W RPQC L VLTG P P VC RPALLD FASQ FTK GK GL M IC GS V IQ GPR LE CVKE AQAAE AK I Q T 631
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 738 WL I KNK I KAFYA A V A AD CF R D GVR S L L QASGLGRMKPNTLV I GYKK N WR K A PLTEI E N Y V GIIHDAFD FEIG VV I VR I S Q 817
Cdd:TIGR00930 632 WL E KNK V KAFYA V V V AD DL R E GVR H L I QASGLGRMKPNTLV M GYKK D WR Q A EPRAW E T Y I GIIHDAFD AHLA VV V VR N S E 711
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 818 G FD IS q VLQVQEELE rleqerlaleatikd N E C E E E S ggirglfkkagklnitkt TPKK DG S I N T SQS MH vgefnqkl V E 897
Cdd:TIGR00930 712 G LP IS - VLQVQEELE --------------- N D C S E D S ------------------ IELN DG K I S T QPD MH -------- L E 749
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 898 ASTQF K KKQ E KGTIDVWWL F DDGGLTLL I PY I LT LR K K WK D CK L RI Y VG G - K IN R I E E EK IV MA S LL S KFRI KFAD I HII 976
Cdd:TIGR00930 750 ASTQF Q KKQ G KGTIDVWWL V DDGGLTLL L PY L LT TK K V WK K CK I RI F VG A q K DD R S E Q EK KD MA T LL Y KFRI DAEV I VVL 829
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 977 G DIN IR P NK ES WKV FEEMI E P Y RLH ESC KD LTTAE - K LKRET PWKITDAEL EAVKE KSYRQVRLNELL Q E H SR A A N L I VL 1055
Cdd:TIGR00930 830 M DIN AK P QT ES MEA FEEMI R P F RLH KTE KD REAKD p K MTWTK PWKITDAEL QSNVR KSYRQVRLNELL L E Y SR D A A L V VL 909
970 980 990 1000
....*....|....*....|....*....|....*....|....
gi 1847688283 1056 SLPV A RKGSI S D L LYMAWLE I L TKN LPPVLLVRGNH K NVLTFYS 1099
Cdd:TIGR00930 910 SLPV P RKGSI P D E LYMAWLE V L SED LPPVLLVRGNH R NVLTFYS 953
SLC12
pfam03522 Solute carrier family 12;
694-1099
0e+00
Solute carrier family 12;
Pssm-ID: 460955
Cd Length: 414
Bit Score: 596.91
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 694 RPAL L D IT H AF TKN SG L C IC CE V FV G PRKLCVKEMN sg MA K KQA WL I K N KIKAFYA A V AA D CF R D G VRS LLQASGLG RM K 773
Cdd:pfam03522 1 RPAL V D FA H LI TKN VS L M IC GH V VK G RLSQKLRSEL -- QK K AYR WL R K R KIKAFYA L V DG D NL R E G AQA LLQASGLG KL K 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 774 PN T L VI GYK KN WR KAPLT E I E N Y VGI IHDAFD FEIG V V I V R ISQ G F D I S QV LQ V Q EEL E RLEQERLALEATIKDN E CEEE 853
Cdd:pfam03522 79 PN I L LM GYK SD WR TCDKE E L E E Y FNV IHDAFD LQYA V A I L R LPE G L D V S HL LQ D Q DTE E LGLGDETNSSYAEQSS E EQST 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 854 S GGIRGLF K KAGK --------- LNITKTT P KKDG S INTSQSMHVGEF -------- NQKLVEAS TQF K KKQ E KGTIDVWWL 916
Cdd:pfam03522 159 S NSKQDDD K SKLS kkdsnlsls PDKSTKN P SGKD S SKSDKLKKKSPS iilrtasn EKEILNNI TQF Q KKQ K KGTIDVWWL 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 917 F DDGGLTLL I PYIL TL R K KW K DCKLR IYVG G - KINRI EEE KIV MASLLSKFRI KFA D IHI I G DI NIR P N KE SW K V F E E M I 995
Cdd:pfam03522 239 Y DDGGLTLL L PYIL ST R S KW S DCKLR VFAL G n RKDEL EEE QRN MASLLSKFRI DYS D LTV I P DI TKK P K KE TK K F F D E L I 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 996 EP Y RLHE SC K DL ttaeklkr E TPW KITD A ELEA V KEK SY RQ V RL N ELL Q EHS RA ANLIV LS LP VA RKG SI S DL LYMAWLE 1075
Cdd:pfam03522 319 EP F RLHE DD K EE -------- E SAE KITD S ELEA L KEK TN RQ L RL R ELL L EHS SD ANLIV MT LP MP RKG TV S AP LYMAWLE 390
410 420
....*....|....*....|....
gi 1847688283 1076 I LTK N LPP V LLVRGN HKN VLTFYS 1099
Cdd:pfam03522 391 T LTK D LPP F LLVRGN QTS VLTFYS 414
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
219-649
1.22e-33
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 135.41
E-value: 1.22e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 219 A VTVTGITG LS TSAI A TN g CV R G GGAY YLIS R S LGP EF G GSI G LIFAFANAV AVA MYV V G F AETVVD L L kesdsmmvd P T 298
Cdd:COG0531 53 A GLLALLVA LS YAEL A SA - FP R A GGAY TYAR R A LGP LL G FLA G WALLLSYVL AVA AVA V A F GGYLSS L F --------- P A 122
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 299 NDIRI I GSITVVI L LGISVA G MEWE AK AQV IL L V IL L IAIAN F FIG tvipsnnekksr G F F NYQASI F A e N F G P RFTKGE 378
Cdd:COG0531 123 GGSVL I ALVLILL L TLLNLR G VKES AK VNN IL T V LK L LVLLL F IVV ------------ G L F AFDPAN F T - P F L P AGGGLS 189
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 379 G FFSVF A IF F P A A TG IL A G AN ISGDLED P QDA IPR GTM L AIF I TT V A Y LG V AICVGAC V VR D ATGNMNDTI isgmncngs 458
Cdd:COG0531 190 G VLAAL A LA F F A F TG FE A I AN LAEEAKN P KRN IPR AII L SLL I VG V L Y IL V SLALTGV V PY D ELAASGAPL --------- 260
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 459 aacglgydfsrcrhepcqyglmnn FQVMSM V S G -- FGP LI TA G IFSAT L SSAL AS LVS A PKVFQ A LCK D NI yk ALQF FAK 536
Cdd:COG0531 261 ------------------------ ADAAEA V F G pw GAI LI AL G ALLSL L GALN AS ILG A SRLLY A MAR D GL -- LPKV FAK 314
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 537 GYGKNNE P LRGYI LT FL IA MAFI L I -- A ELNTI A PII S NFF L AS Y A L INFSCFHASY a KS P GWRPAYGIYNMWVSLF G AV 614
Cdd:COG0531 315 VHPRFGT P VNAIL LT GV IA LLLL L L ga A SFTAL A SLA S VGV L LA Y L L VALAVIVLRR - RR P DLPRPFRVPLPLIPIL G IL 393
410 420 430
....*....|....*....|....*....|....*...
gi 1847688283 615 LC CAVMFVINWW A --- AVITYV I EFF LY VYVTCKK P DV 649
Cdd:COG0531 394 LC LFLLYLLGPG A lli GLVLLA I GLL LY LLYRRRH P KL 431
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
104-1099
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1480.34
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 104 NT M DAVP K IE Y YRN TGSIS GPK V NRPSL L E I H EQ L A K N V AVTPSS AD RVA NG D G IPGD E Q AE N ---- KE DDQ AG V VKFGW 179
Cdd:TIGR00930 1 NT V DAVP R IE H YRN SEGQG GPK R NRPSL E E L H DL L D K V V SLLGPL AD YTN NG Q G MKEH E E AE D aegt KE KPP AG A VKFGW 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 180 V K GVLV R C M LNIWGV M LF I RLSWIVG E AGIGL GVI II G L AVT VT G ITGLS T SAIATNG C V R GGGAYYLISRSLGPEFGGS 259
Cdd:TIGR00930 81 V M GVLV P C L LNIWGV I LF L RLSWIVG Q AGIGL SLL II L L CCC VT T ITGLS M SAIATNG V V K GGGAYYLISRSLGPEFGGS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 260 IGLIFAFANAVAVAMYVVGFAETV V DLL K E SD S - M MVDP T NDIRI I G SI TVV I LLGIS V AGMEWE A KAQV IL LVI L L IA I 338
Cdd:TIGR00930 161 IGLIFAFANAVAVAMYVVGFAETV L DLL R E NG S k I MVDP I NDIRI Y G TV TVV V LLGIS F AGMEWE N KAQV LF LVI V L LS I 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 339 A N F F I GT V IP SNN e K KSR GFF NYQAS IF A ENF G P RFTKG EG - FFS V F A IFFP AA TGILAGANISGDL E DPQ D AIP R GT M L 417
Cdd:TIGR00930 241 L N I F V GT I IP AFD - K PAK GFF GLGNE IF S ENF I P GIPGP EG g FFS L F G IFFP SV TGILAGANISGDL K DPQ K AIP K GT L L 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 418 AI FI TTV A YLG VAICV GACVVRDATG NM NDT IIS gmn CNG SAAC glgyd FS R C R H EP C Q YGLMNN F QVMS M VS G F G PLIT 497
Cdd:TIGR00930 320 AI LT TTV V YLG SVVLF GACVVRDATG DK NDT LVT --- NCT SAAC ----- FS E C A H NT C S YGLMNN L QVMS L VS P F P PLIT 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 498 AGIFSATLSSALASLVSAP KV FQALCKDNIY KA LQFF A KGYGKN N EPLR G Y I LT FL IA MA FILIAELNTIAPIISNFFLA 577
Cdd:TIGR00930 392 AGIFSATLSSALASLVSAP RL FQALCKDNIY PF LQFF G KGYGKN G EPLR A Y L LT AF IA EG FILIAELNTIAPIISNFFLA 471
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 578 SYALINFSCFHAS YAK SPGWRP AYGI Y NM W V SL F GA V LCCA V MF V I N WWAA VITY VI EF FLY V YVT C KKPDVNWGSSTQA 657
Cdd:TIGR00930 472 SYALINFSCFHAS LLR SPGWRP RFKY Y HW W L SL L GA S LCCA I MF L I S WWAA LVAM VI AL FLY K YVT Y KKPDVNWGSSTQA 551
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 658 LSY VS AL DNA L E L TT VEDHVKN F RPQC I VLTG G P MT RPALLD ITHA FTK NS GL C IC CE V FV GPR KL CVKE MNSGM AK K Q A 737
Cdd:TIGR00930 552 LSY SL AL YSL L R L EE VEDHVKN W RPQC L VLTG P P VC RPALLD FASQ FTK GK GL M IC GS V IQ GPR LE CVKE AQAAE AK I Q T 631
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 738 WL I KNK I KAFYA A V A AD CF R D GVR S L L QASGLGRMKPNTLV I GYKK N WR K A PLTEI E N Y V GIIHDAFD FEIG VV I VR I S Q 817
Cdd:TIGR00930 632 WL E KNK V KAFYA V V V AD DL R E GVR H L I QASGLGRMKPNTLV M GYKK D WR Q A EPRAW E T Y I GIIHDAFD AHLA VV V VR N S E 711
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 818 G FD IS q VLQVQEELE rleqerlaleatikd N E C E E E S ggirglfkkagklnitkt TPKK DG S I N T SQS MH vgefnqkl V E 897
Cdd:TIGR00930 712 G LP IS - VLQVQEELE --------------- N D C S E D S ------------------ IELN DG K I S T QPD MH -------- L E 749
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 898 ASTQF K KKQ E KGTIDVWWL F DDGGLTLL I PY I LT LR K K WK D CK L RI Y VG G - K IN R I E E EK IV MA S LL S KFRI KFAD I HII 976
Cdd:TIGR00930 750 ASTQF Q KKQ G KGTIDVWWL V DDGGLTLL L PY L LT TK K V WK K CK I RI F VG A q K DD R S E Q EK KD MA T LL Y KFRI DAEV I VVL 829
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 977 G DIN IR P NK ES WKV FEEMI E P Y RLH ESC KD LTTAE - K LKRET PWKITDAEL EAVKE KSYRQVRLNELL Q E H SR A A N L I VL 1055
Cdd:TIGR00930 830 M DIN AK P QT ES MEA FEEMI R P F RLH KTE KD REAKD p K MTWTK PWKITDAEL QSNVR KSYRQVRLNELL L E Y SR D A A L V VL 909
970 980 990 1000
....*....|....*....|....*....|....*....|....
gi 1847688283 1056 SLPV A RKGSI S D L LYMAWLE I L TKN LPPVLLVRGNH K NVLTFYS 1099
Cdd:TIGR00930 910 SLPV P RKGSI P D E LYMAWLE V L SED LPPVLLVRGNH R NVLTFYS 953
SLC12
pfam03522 Solute carrier family 12;
694-1099
0e+00
Solute carrier family 12;
Pssm-ID: 460955
Cd Length: 414
Bit Score: 596.91
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 694 RPAL L D IT H AF TKN SG L C IC CE V FV G PRKLCVKEMN sg MA K KQA WL I K N KIKAFYA A V AA D CF R D G VRS LLQASGLG RM K 773
Cdd:pfam03522 1 RPAL V D FA H LI TKN VS L M IC GH V VK G RLSQKLRSEL -- QK K AYR WL R K R KIKAFYA L V DG D NL R E G AQA LLQASGLG KL K 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 774 PN T L VI GYK KN WR KAPLT E I E N Y VGI IHDAFD FEIG V V I V R ISQ G F D I S QV LQ V Q EEL E RLEQERLALEATIKDN E CEEE 853
Cdd:pfam03522 79 PN I L LM GYK SD WR TCDKE E L E E Y FNV IHDAFD LQYA V A I L R LPE G L D V S HL LQ D Q DTE E LGLGDETNSSYAEQSS E EQST 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 854 S GGIRGLF K KAGK --------- LNITKTT P KKDG S INTSQSMHVGEF -------- NQKLVEAS TQF K KKQ E KGTIDVWWL 916
Cdd:pfam03522 159 S NSKQDDD K SKLS kkdsnlsls PDKSTKN P SGKD S SKSDKLKKKSPS iilrtasn EKEILNNI TQF Q KKQ K KGTIDVWWL 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 917 F DDGGLTLL I PYIL TL R K KW K DCKLR IYVG G - KINRI EEE KIV MASLLSKFRI KFA D IHI I G DI NIR P N KE SW K V F E E M I 995
Cdd:pfam03522 239 Y DDGGLTLL L PYIL ST R S KW S DCKLR VFAL G n RKDEL EEE QRN MASLLSKFRI DYS D LTV I P DI TKK P K KE TK K F F D E L I 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 996 EP Y RLHE SC K DL ttaeklkr E TPW KITD A ELEA V KEK SY RQ V RL N ELL Q EHS RA ANLIV LS LP VA RKG SI S DL LYMAWLE 1075
Cdd:pfam03522 319 EP F RLHE DD K EE -------- E SAE KITD S ELEA L KEK TN RQ L RL R ELL L EHS SD ANLIV MT LP MP RKG TV S AP LYMAWLE 390
410 420
....*....|....*....|....
gi 1847688283 1076 I LTK N LPP V LLVRGN HKN VLTFYS 1099
Cdd:pfam03522 391 T LTK D LPP F LLVRGN QTS VLTFYS 414
AA_permease
pfam00324 Amino acid permease;
182-685
2.94e-119
Amino acid permease;
Pssm-ID: 366028 [Multi-domain]
Cd Length: 467
Bit Score: 375.50
E-value: 2.94e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 182 G V LVRCMLNIW G VM LF IRLSWIV G E AG IGLGVIIIGLAVT V TGITG LS TSA I A TNG c VRG GG A Y YLI SR S LGP EF G GSI G 261
Cdd:pfam00324 1 H V QMIALGGVI G TG LF VGSGSVL G Q AG PAGALLGYLISGV V IFLVM LS LGE I S TNG - PVS GG F Y TYA SR F LGP SL G FAT G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 262 L ------ I FAF A NAVAV A MYVVG F A E T V V D LLKES dsmmvdptndir II G SITV V I L LG I SVA G ME W EAK A QVILLV I LL 335
Cdd:pfam00324 80 W nywlsw I TVL A LELTA A SILIQ F W E L V P D IPYLW ------------ VW G AVFL V L L TI I NLV G VK W YGE A EFWFAL I KI 147
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 336 IAI AN F F I GTV I PSNNEKKSR G -- F FNYQASIFAE NF G P R F T KG eg F F SVF A I F F P A A TGI LAGANIS G DLED P QDA IP R 413
Cdd:pfam00324 148 IAI IG F I I VGI I LLSGGNPND G ai F RYLGDNGGKN NF P P G F G KG -- F I SVF V I A F F A F TGI ELVGIAA G EVKN P EKS IP K 225
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 414 GTMLA I FIT T VA Y LGVAICV G AC V VRDAT G NM ND TIIS gmncngsaacglgydfsrcrhepcq YGLMNN F QVMSMV SG FG 493
Cdd:pfam00324 226 AILQV I WRI T IF Y ILSLLAI G LL V PWNDP G LL ND SASA ------------------------- ASPFVI F FKFLGI SG LA 280
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 494 PLI T A G I FS A T LS S A LA SL V S APKVFQA L CK D NIYK alq F F A K GYG K NNE PLR GYILTFL I AMAFI L I A E LN TI ap I IS N 573
Cdd:pfam00324 281 PLI N A V I LT A A LS A A NS SL Y S GSRMLYS L AR D GLAP --- K F L K KVD K RGV PLR AILVSMV I SLLAL L L A S LN PA -- I VF N 355
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 574 F F LA SYA L INFSCFHASYAKSPGW R P A YGIYNMWVSLFGAVLCCAVMF VI NWW AA V I TYV I EF FLY VYVTCKKPDV NWG S 653
Cdd:pfam00324 356 F L LA ISG L SGLIVWGLISLSHLRF R K A FKYQGRSIDELPFKAPLGPLG VI LGL AA I I IIL I IQ FLY AFLPVPGGPK NWG A 435
490 500 510
....*....|....*....|....*....|..
gi 1847688283 654 STQ A LS Y VSA L DNALE L TT V ED HVKN FR PQ CI 685
Cdd:pfam00324 436 GSF A AA Y LIV L LFLII L IG V KL HVKN WK PQ LL 467
AA_permease_N
pfam08403 Amino acid permease N-terminal; This domain is found to the N-terminus of the amino acid ...
90-157
1.37e-36
Amino acid permease N-terminal; This domain is found to the N-terminus of the amino acid permease domain (pfam00324) in metazoan Na-K-Cl cotransporters.
Pssm-ID: 429977
Cd Length: 70
Bit Score: 132.18
E-value: 1.37e-36
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 90 D S H TN TYYLQTFGHNT M DAVP K I EY YRNTGS I SG P K VN RPSL L E I H E QL A KN V -- AV TPS S A D R V A NGDG 157
Cdd:pfam08403 1 D T H GS TYYLQTFGHNT L DAVP R I DF YRNTGS V SG V K KS RPSL A E L H S QL K KN S al AV AEG S V D G V E NGDG 70
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
219-649
1.22e-33
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 135.41
E-value: 1.22e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 219 A VTVTGITG LS TSAI A TN g CV R G GGAY YLIS R S LGP EF G GSI G LIFAFANAV AVA MYV V G F AETVVD L L kesdsmmvd P T 298
Cdd:COG0531 53 A GLLALLVA LS YAEL A SA - FP R A GGAY TYAR R A LGP LL G FLA G WALLLSYVL AVA AVA V A F GGYLSS L F --------- P A 122
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 299 NDIRI I GSITVVI L LGISVA G MEWE AK AQV IL L V IL L IAIAN F FIG tvipsnnekksr G F F NYQASI F A e N F G P RFTKGE 378
Cdd:COG0531 123 GGSVL I ALVLILL L TLLNLR G VKES AK VNN IL T V LK L LVLLL F IVV ------------ G L F AFDPAN F T - P F L P AGGGLS 189
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 379 G FFSVF A IF F P A A TG IL A G AN ISGDLED P QDA IPR GTM L AIF I TT V A Y LG V AICVGAC V VR D ATGNMNDTI isgmncngs 458
Cdd:COG0531 190 G VLAAL A LA F F A F TG FE A I AN LAEEAKN P KRN IPR AII L SLL I VG V L Y IL V SLALTGV V PY D ELAASGAPL --------- 260
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 459 aacglgydfsrcrhepcqyglmnn FQVMSM V S G -- FGP LI TA G IFSAT L SSAL AS LVS A PKVFQ A LCK D NI yk ALQF FAK 536
Cdd:COG0531 261 ------------------------ ADAAEA V F G pw GAI LI AL G ALLSL L GALN AS ILG A SRLLY A MAR D GL -- LPKV FAK 314
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 537 GYGKNNE P LRGYI LT FL IA MAFI L I -- A ELNTI A PII S NFF L AS Y A L INFSCFHASY a KS P GWRPAYGIYNMWVSLF G AV 614
Cdd:COG0531 315 VHPRFGT P VNAIL LT GV IA LLLL L L ga A SFTAL A SLA S VGV L LA Y L L VALAVIVLRR - RR P DLPRPFRVPLPLIPIL G IL 393
410 420 430
....*....|....*....|....*....|....*...
gi 1847688283 615 LC CAVMFVINWW A --- AVITYV I EFF LY VYVTCKK P DV 649
Cdd:COG0531 394 LC LFLLYLLGPG A lli GLVLLA I GLL LY LLYRRRH P KL 431
AA_permease_2
pfam13520 Amino acid permease;
240-643
2.95e-14
Amino acid permease;
Pssm-ID: 404414 [Multi-domain]
Cd Length: 427
Bit Score: 76.19
E-value: 2.95e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 240 R G GG A Y YLISRSL G PEFGGSI G LIFA FA NAVAV A MYVVGF A ETVVDL L KES dsm M V DP T NDIRI I GSITVV I LLG I SVA G 319
Cdd:pfam13520 60 R S GG I Y VYLENAF G KFVAFLA G WSNW FA YVLGL A SSASVA A SYLLSA L GPD --- L V PT T WLTYG I AIAILI I FAI I NIR G 136
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 320 MEWE AK A Q V IL LVIL L IAIANFF I GTVIP snne KKSR G F FN Y q A S IFAEN F G P RFTK G eg F F SV F AIFFPAA TG ILAG AN 399
Cdd:pfam13520 137 VRES AK I Q N IL GILK L LLPLILI I ILGLV ---- TADG G G FN L - L S GEWHT F F P DGWP G -- V F AG F LGVLWSF TG FESA AN 209
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 400 I S G dl E DPQDAI P RGTMLAIF I TT V A Y LG V A I CVGAC V VR D ATGNMNDTIISG mncngsaacglgydfsrcrhepcqy G L 479
Cdd:pfam13520 210 V S E -- E VKKRNV P KAIFIGVI I VG V L Y IL V N I AFFGV V PD D EIALSSGLGQVA ------------------------- A L 262
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 480 MNNFQVMSMVSGF gpl ITAGIFSAT L SSALASL V S A PKVFQ AL CK D NIYKALQ FFAK g YG K NNE P L R GY ILT FLIAMAFI 559
Cdd:pfam13520 263 LFQAVGGKWGAII --- VVILLALSL L GAVNTAI V G A SRLLY AL AR D GVLPFSR FFAK - VN K FGS P I R AI ILT AILSLILL 338
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847688283 560 L I ----- A EL N TIAPIISNFF L A SY A L INFSCFHASYAKSPGW R payg I YNM W VSLFGAV L CCAVMF V INWWAA V ITYVI 634
Cdd:pfam13520 339 L L fllsp A AY N ALLSLSAYGY L L SY L L PIIGLLILRKKRPDLG R ---- I PGR W PVAIFGI L FSLFLI V ALFFPP V GPATG 414
....*....
gi 1847688283 635 EFFL Y VYVT 643
Cdd:pfam13520 415 SSLN Y AIIL 423
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
