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Conserved domains on  [gi|1822188060|ref|NP_001365982|]
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cytosolic Fe-S cluster assembly factor NUBP2 isoform 2 [Mus musculus]

Protein Classification

Mrp/NBP35 family ATP-binding protein( domain architecture ID 10566257)

MRP (Multiple Resistance and pH adaptation)/NBP35 (Nucleotide-binding protein 35) family ATP-binding protein, similar to the yeast cytosolic iron-sulfur (Fe-S) assembly factors, NBP35 and CFD1 (also called NUBP1/NUBP2 in higher eukaryotes), which functions as a heterotetrameric complex to assemble nascent Fe-S clusters and transfer them to apoprotein targets

Gene Ontology:  GO:0005524|GO:0016887|GO:0046872
PubMed:  11916378

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ParA pfam10609
NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid ...
 1-203 5.55e-102

NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.


:

Pssm-ID: 431392 [Multi-domain]  Cd Length: 246  Bit Score: 294.75  E-value: 5.55e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060   1 MLRAQGKAVHQCDNGWVPVFVDqeqSISLMSVGFLLENPDEAVVWRGPKKHALIKQFVSDVAWGQLDYLVVDTPPGTSDE 80
Cdd:pfam10609  50 MLGLEGERPEQSDGGIIPVEAH---GIKVMSIGFLLPDEDDAVIWRGPMKSGAIKQFLTDVDWGELDYLIIDLPPGTGDE 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060  81 HMATMEALrpyrPL-GALVVTTPQAVSIGDVRRELTFCKKTGLQVIGVIENMSGFTCPHCAECTNVFSSGSGEELARLAG 159
Cdd:pfam10609 127 QLTLAQLL----PLtGAVIVTTPQDVALLDVRKAIDMFKKVNVPVLGVVENMSYFVCPHCGEETYIFGKGGGEKLAEELG 202

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1822188060 160 VPFLGSVPLDSQLTRSLEEGRDFIQEFPKSTAYSALTSIAQRVV 203
Cdd:pfam10609 203 VPFLGEIPLDPDIREAGDEGKPFVLADPDSPAAKAFLKIADKVA 246
 
Name Accession Description Interval E-value
ParA pfam10609
NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid ...
 1-203 5.55e-102

NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.


Pssm-ID: 431392 [Multi-domain]  Cd Length: 246  Bit Score: 294.75  E-value: 5.55e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060   1 MLRAQGKAVHQCDNGWVPVFVDqeqSISLMSVGFLLENPDEAVVWRGPKKHALIKQFVSDVAWGQLDYLVVDTPPGTSDE 80
Cdd:pfam10609  50 MLGLEGERPEQSDGGIIPVEAH---GIKVMSIGFLLPDEDDAVIWRGPMKSGAIKQFLTDVDWGELDYLIIDLPPGTGDE 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060  81 HMATMEALrpyrPL-GALVVTTPQAVSIGDVRRELTFCKKTGLQVIGVIENMSGFTCPHCAECTNVFSSGSGEELARLAG 159
Cdd:pfam10609 127 QLTLAQLL----PLtGAVIVTTPQDVALLDVRKAIDMFKKVNVPVLGVVENMSYFVCPHCGEETYIFGKGGGEKLAEELG 202

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1822188060 160 VPFLGSVPLDSQLTRSLEEGRDFIQEFPKSTAYSALTSIAQRVV 203
Cdd:pfam10609 203 VPFLGEIPLDPDIREAGDEGKPFVLADPDSPAAKAFLKIADKVA 246
Mrp_NBP35 cd02037
Mrp/NBP35 ATP-binding protein family; Mrp/NBP35 ATP-binding family protein are typically ...
 1-173 3.11e-91

Mrp/NBP35 ATP-binding protein family; Mrp/NBP35 ATP-binding family protein are typically iron-sulfur (FeS) cluster scaffolds that function to assemble nascent FeS clusters for transfer to FeS-requiring enzymes. Members include the eukaryotic nucleotide-binding protein 1 (NUBP1) which is a component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery and the archael [NiFe] hydrogenase maturation protein HypB which is required for nickel insertion into [NiFe] hydrogenase.


Pssm-ID: 349757 [Multi-domain]  Cd Length: 213  Bit Score: 266.29  E-value: 3.11e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060   1 MLRAQGKAVHQCDNGWVPVFVDqeqSISLMSVGFLLEnPDEAVVWRGPKKHALIKQFVSDVAWGQLDYLVVDTPPGTSDE 80
Cdd:cd02037    47 LLGVEGKPLHQSEEGIVPVEVG---GIKVMSIGFLLP-EDDAVIWRGPMKSGAIKQFLKDVDWGELDYLIIDLPPGTGDE 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060  81 HMATMEALRPYrplGALVVTTPQAVSIGDVRRELTFCKKTGLQVIGVIENMSGFTCPHCAECTNVFSSGSGEELARLAGV 160
Cdd:cd02037   123 HLSLVQLIPID---GAVVVTTPQEVSLIDVRKAIDMCKKLNIPVLGIVENMSGFVCPHCGKKIYIFGKGGGEKLAEELGV 199

                         170
                  ....*....|...
gi 1822188060 161 PFLGSVPLDSQLT 173
Cdd:cd02037   200 PFLGKIPLDPELA 212
MrpORP NF041136
iron-sulfur cluster carrier protein MrpORP;
1-203 1.03e-84

iron-sulfur cluster carrier protein MrpORP;


Pssm-ID: 469059 [Multi-domain]  Cd Length: 365  Bit Score: 255.13  E-value: 1.03e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060   1 MLRAQGKAVHQCDNGWVPVFVDQeqSISLMSVGFLLENPDEAVVWRGPKKHALIKQFVSDVAWGQLDYLVVDTPPGTSDE 80
Cdd:NF041136   52 LLGLEGKRLGSEDEGILPVEYSD--NLKVMSIGFLLENRDDAVIWRGPVKMGVIKQFLSDVEWGDLDYLIIDSPPGTGDE 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060  81 HMATMEALrpyrPL-GALVVTTPQAVSIGDVRRELTFCKKTGLQVIGVIENMSGFTCPHCAECTNVFSSGSGEELARLAG 159
Cdd:NF041136  130 PLSVAQLI----PDaGAVIVTTPQELALADVRKSINFCRKLNIPILGIVENMSGFVCPHCGKEIDIFKSGGGEKLAEEMG 205

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1822188060 160 VPFLGSVPLDSQLTRSLEEGRDFIQEFPKSTAYSALTSIAQRVV 203
Cdd:NF041136  206 VPFLGRIPIDPEIVEAGDAGRPFVLDYAWSPAAKALEKIVDPIL 249
PRK11670 PRK11670
iron-sulfur cluster carrier protein ApbC;
31-206 9.28e-31

iron-sulfur cluster carrier protein ApbC;


Pssm-ID: 183270 [Multi-domain]  Cd Length: 369  Bit Score: 115.53  E-value: 9.28e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060  31 SVGFLLEnPDEAVVWRGPKKHALIKQFVSDVAWGQLDYLVVDTPPGTSDEHMaTMEALRPYRplGALVVTTPQAVSIGDV 110
Cdd:PRK11670  182 SIGYLVT-DDNAMVWRGPMASKALMQMLQETLWPDLDYLVLDMPPGTGDIQL-TLAQNIPVT--GAVVVTTPQDIALIDA 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060 111 RRELTFCKKTGLQVIGVIENMSGFTCPHCAECTNVFSSGSGEELARLAGVPFLGSVPLDSQLTRSLEEGRDFIQEFPKST 190
Cdd:PRK11670  258 KKGIVMFEKVEVPVLGIVENMSMHICSNCGHHEPIFGTGGAEKLAEKYHTQLLGQMPLHISLREDLDRGTPTVVSRPESE 337

                         170
                  ....*....|....*.
gi 1822188060 191 AYSALTSIAQRVVHRM 206
Cdd:PRK11670  338 FTAIYRQLADRVAAQL 353
Mrp COG0489
Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, ...
 27-138 1.45e-19

Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440255 [Multi-domain]  Cd Length: 289  Bit Score: 84.08  E-value: 1.45e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060  27 ISLMSVGFLLENPDEAVVwrgpkkHALIKQFVSDVAwGQLDYLVVDTPPGTSDEHMATMEALRPyrplGALVVTTPQAVS 106
Cdd:COG0489   170 LDVLPAGPLPPNPSELLA------SKRLKQLLEELR-GRYDYVIIDTPPGLGVADATLLASLVD----GVLLVVRPGKTA 238

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1822188060 107 IGDVRRELTFCKKTGLQVIGVIENMsgfTCPH 138
Cdd:COG0489   239 LDDVRKALEMLEKAGVPVLGVVLNM---VCPK 267
 
Name Accession Description Interval E-value
ParA pfam10609
NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid ...
 1-203 5.55e-102

NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.


Pssm-ID: 431392 [Multi-domain]  Cd Length: 246  Bit Score: 294.75  E-value: 5.55e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060   1 MLRAQGKAVHQCDNGWVPVFVDqeqSISLMSVGFLLENPDEAVVWRGPKKHALIKQFVSDVAWGQLDYLVVDTPPGTSDE 80
Cdd:pfam10609  50 MLGLEGERPEQSDGGIIPVEAH---GIKVMSIGFLLPDEDDAVIWRGPMKSGAIKQFLTDVDWGELDYLIIDLPPGTGDE 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060  81 HMATMEALrpyrPL-GALVVTTPQAVSIGDVRRELTFCKKTGLQVIGVIENMSGFTCPHCAECTNVFSSGSGEELARLAG 159
Cdd:pfam10609 127 QLTLAQLL----PLtGAVIVTTPQDVALLDVRKAIDMFKKVNVPVLGVVENMSYFVCPHCGEETYIFGKGGGEKLAEELG 202

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1822188060 160 VPFLGSVPLDSQLTRSLEEGRDFIQEFPKSTAYSALTSIAQRVV 203
Cdd:pfam10609 203 VPFLGEIPLDPDIREAGDEGKPFVLADPDSPAAKAFLKIADKVA 246
Mrp_NBP35 cd02037
Mrp/NBP35 ATP-binding protein family; Mrp/NBP35 ATP-binding family protein are typically ...
 1-173 3.11e-91

Mrp/NBP35 ATP-binding protein family; Mrp/NBP35 ATP-binding family protein are typically iron-sulfur (FeS) cluster scaffolds that function to assemble nascent FeS clusters for transfer to FeS-requiring enzymes. Members include the eukaryotic nucleotide-binding protein 1 (NUBP1) which is a component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery and the archael [NiFe] hydrogenase maturation protein HypB which is required for nickel insertion into [NiFe] hydrogenase.


Pssm-ID: 349757 [Multi-domain]  Cd Length: 213  Bit Score: 266.29  E-value: 3.11e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060   1 MLRAQGKAVHQCDNGWVPVFVDqeqSISLMSVGFLLEnPDEAVVWRGPKKHALIKQFVSDVAWGQLDYLVVDTPPGTSDE 80
Cdd:cd02037    47 LLGVEGKPLHQSEEGIVPVEVG---GIKVMSIGFLLP-EDDAVIWRGPMKSGAIKQFLKDVDWGELDYLIIDLPPGTGDE 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060  81 HMATMEALRPYrplGALVVTTPQAVSIGDVRRELTFCKKTGLQVIGVIENMSGFTCPHCAECTNVFSSGSGEELARLAGV 160
Cdd:cd02037   123 HLSLVQLIPID---GAVVVTTPQEVSLIDVRKAIDMCKKLNIPVLGIVENMSGFVCPHCGKKIYIFGKGGGEKLAEELGV 199

                         170
                  ....*....|...
gi 1822188060 161 PFLGSVPLDSQLT 173
Cdd:cd02037   200 PFLGKIPLDPELA 212
MrpORP NF041136
iron-sulfur cluster carrier protein MrpORP;
1-203 1.03e-84

iron-sulfur cluster carrier protein MrpORP;


Pssm-ID: 469059 [Multi-domain]  Cd Length: 365  Bit Score: 255.13  E-value: 1.03e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060   1 MLRAQGKAVHQCDNGWVPVFVDQeqSISLMSVGFLLENPDEAVVWRGPKKHALIKQFVSDVAWGQLDYLVVDTPPGTSDE 80
Cdd:NF041136   52 LLGLEGKRLGSEDEGILPVEYSD--NLKVMSIGFLLENRDDAVIWRGPVKMGVIKQFLSDVEWGDLDYLIIDSPPGTGDE 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060  81 HMATMEALrpyrPL-GALVVTTPQAVSIGDVRRELTFCKKTGLQVIGVIENMSGFTCPHCAECTNVFSSGSGEELARLAG 159
Cdd:NF041136  130 PLSVAQLI----PDaGAVIVTTPQELALADVRKSINFCRKLNIPILGIVENMSGFVCPHCGKEIDIFKSGGGEKLAEEMG 205

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1822188060 160 VPFLGSVPLDSQLTRSLEEGRDFIQEFPKSTAYSALTSIAQRVV 203
Cdd:NF041136  206 VPFLGRIPIDPEIVEAGDAGRPFVLDYAWSPAAKALEKIVDPIL 249
PRK11670 PRK11670
iron-sulfur cluster carrier protein ApbC;
31-206 9.28e-31

iron-sulfur cluster carrier protein ApbC;


Pssm-ID: 183270 [Multi-domain]  Cd Length: 369  Bit Score: 115.53  E-value: 9.28e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060  31 SVGFLLEnPDEAVVWRGPKKHALIKQFVSDVAWGQLDYLVVDTPPGTSDEHMaTMEALRPYRplGALVVTTPQAVSIGDV 110
Cdd:PRK11670  182 SIGYLVT-DDNAMVWRGPMASKALMQMLQETLWPDLDYLVLDMPPGTGDIQL-TLAQNIPVT--GAVVVTTPQDIALIDA 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060 111 RRELTFCKKTGLQVIGVIENMSGFTCPHCAECTNVFSSGSGEELARLAGVPFLGSVPLDSQLTRSLEEGRDFIQEFPKST 190
Cdd:PRK11670  258 KKGIVMFEKVEVPVLGIVENMSMHICSNCGHHEPIFGTGGAEKLAEKYHTQLLGQMPLHISLREDLDRGTPTVVSRPESE 337

                         170
                  ....*....|....*.
gi 1822188060 191 AYSALTSIAQRVVHRM 206
Cdd:PRK11670  338 FTAIYRQLADRVAAQL 353
Mrp COG0489
Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, ...
 27-138 1.45e-19

Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440255 [Multi-domain]  Cd Length: 289  Bit Score: 84.08  E-value: 1.45e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060  27 ISLMSVGFLLENPDEAVVwrgpkkHALIKQFVSDVAwGQLDYLVVDTPPGTSDEHMATMEALRPyrplGALVVTTPQAVS 106
Cdd:COG0489   170 LDVLPAGPLPPNPSELLA------SKRLKQLLEELR-GRYDYVIIDTPPGLGVADATLLASLVD----GVLLVVRPGKTA 238

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1822188060 107 IGDVRRELTFCKKTGLQVIGVIENMsgfTCPH 138
Cdd:COG0489   239 LDDVRKALEMLEKAGVPVLGVVLNM---VCPK 267
FlhG COG0455
MinD-like ATPase FlhG/YlxH, activator of the FlhF-type GTPase [Cell cycle control, cell ...
 64-205 4.03e-13

MinD-like ATPase FlhG/YlxH, activator of the FlhF-type GTPase [Cell cycle control, cell division, chromosome partitioning, Cell motility];


Pssm-ID: 440223 [Multi-domain]  Cd Length: 230  Bit Score: 65.68  E-value: 4.03e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060  64 GQLDYLVVDTPPGTSDEHMATMEAlrpyrplgA---LVVTTPQAVSIGDVRReltFCK----KTGLQVIGVIENMsgftc 136
Cdd:COG0455    92 RFYDVVLVDTGAGISDSVLLFLAA--------AdevVVVTTPEPTSITDAYA---LLKllrrRLGVRRAGVVVNR----- 155

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1822188060 137 phcaectnVFSSGSGEEL-ARLAGV---------PFLGSVPLDSQLTRSLEEGRDFIQEFPKSTAYSALTSIAQRVVHR 205
Cdd:COG0455   156 --------VRSEAEARDVfERLEQVaerflgvrlRVLGVIPEDPAVREAVRRGRPLVLAAPDSPAARAIRELAARLAGW 226
CbiA pfam01656
CobQ/CobB/MinD/ParA nucleotide binding domain; This family consists of various cobyrinic acid ...
 42-182 1.26e-06

CobQ/CobB/MinD/ParA nucleotide binding domain; This family consists of various cobyrinic acid a,c-diamide synthases. These include CbiA and CbiP from S.typhimurium, and CobQ from R. capsulatus. These amidases catalyze amidations to various side chains of hydrogenobyrinic acid or cobyrinic acid a,c-diamide in the biosynthesis of cobalamin (vitamin B12) from uroporphyrinogen III. Vitamin B12 is an important cofactor and an essential nutrient for many plants and animals and is primarily produced by bacteria. The family also contains dethiobiotin synthetases as well as the plasmid partitioning proteins of the MinD/ParA family.


Pssm-ID: 426369 [Multi-domain]  Cd Length: 228  Bit Score: 47.34  E-value: 1.26e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060  42 AVVWRGPKKHALIKQFVSDVAwGQLDYLVVDTPPGTsdeHMATMEALRPyrPLGALVVTTPQAVSIGDVRRELTFCKKTG 121
Cdd:pfam01656  95 EKELLGPRKEERLREALEALK-EDYDYVIIDGAPGL---GELLRNALIA--ADYVIIPLEPEVILVEDAKRLGGVIAALV 168

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1822188060 122 -------LQVIGVIENMSGftcphcaectnvfSSGSGEELA-----RLAGVPFLGSVPLDSQLTRSLEEGRDF 182
Cdd:pfam01656 169 ggyallgLKIIGVVLNKVD-------------GDNHGKLLKealeeLLRGLPVLGVIPRDEAVAEAPARGLPV 228
FlhG-like cd02038
MinD-like ATPase FlhG; FlhG is a member of the SIMIBI superfamily. FlhG (also known as YlxH) ...
 53-191 1.69e-06

MinD-like ATPase FlhG; FlhG is a member of the SIMIBI superfamily. FlhG (also known as YlxH) is a major determinant for a variety of flagellation patterns. It effects location and number of bacterial flagella during C-ring assembly.


Pssm-ID: 349758 [Multi-domain]  Cd Length: 230  Bit Score: 47.18  E-value: 1.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060  53 LIKQFVSDVAwgQLDYLVVDTPPGTSDEhmaTMEALRPYRPLgaLVVTTPQAVSIGD--------VRRELTFckktglqV 124
Cdd:cd02038   100 LIEELSSLES--NYDYLLIDTGAGISRN---VLDFLLAADEV--IVVTTPEPTSITDayalikvlSRRGGKK-------N 165

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1822188060 125 IGVIENMsgftcphcaectnVFSSGSGEELA-RLAGV---------PFLGSVPLDSQLTRSLEEGRDFIQEFPKSTA 191
Cdd:cd02038   166 FRLIVNM-------------ARSPKEGRATFeRLKKVakrfldinlDFVGFIPYDQSVRRAVRSQKPFVLLFPNSKA 229
MinD cd02036
septum site-determining protein MinD; Septum site-determining protein MinD is part of the ...
 67-202 1.85e-06

septum site-determining protein MinD; Septum site-determining protein MinD is part of the operon MinCDE that determines the site of the formation of a septum at mid-cell, an important part of bacterial cell division. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal role, selecting the mid-cell over other sites through the activation and regulation of MinC and MinE. MinD is a membrane-associated ATPase, related to nitrogenase iron protein.


Pssm-ID: 349756 [Multi-domain]  Cd Length: 236  Bit Score: 46.81  E-value: 1.85e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060  67 DYLVVDTPPGT-SDEHMATMEALRpyrplgALVVTTPQAVSIGDVRRELTFCKKTGLQVIGVIENMSGftcPHCAEctnv 145
Cdd:cd02036   112 DFILIDSPAGIeSGFINAIAPADE------AIIVTNPEISSVRDADRVIGLLESKGIVNIGLIVNRYR---PEMVK---- 178

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1822188060 146 fssgSGEELARLA-----GVPFLGSVPLDSQLTRSLEEGRDFIQEFPKSTAYSALTSIAQRV 202
Cdd:cd02036   179 ----SGDMLSVEDiqeilGIPLLGVIPEDPEVIVATNRGEPLVLYKPNSLAAKAFENIARRL 236
SIMIBI cd01983
SIMIBI (signal recognition particle, MinD and BioD)-class NTPases; SIMIBI (after signal ...
 67-131 1.47e-03

SIMIBI (signal recognition particle, MinD and BioD)-class NTPases; SIMIBI (after signal recognition particle, MinD, and BioD), consists of signal recognition particle (SRP) GTPases, the assemblage of MinD-like ATPases, which are involved in protein localization, chromosome partitioning, and membrane transport, and a group of metabolic enzymes with kinase or related phosphate transferase activity. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion.


Pssm-ID: 349751 [Multi-domain]  Cd Length: 107  Bit Score: 37.03  E-value: 1.47e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1822188060  67 DYLVVDTPPGTSDE--HMATMEALRPYRPLGALVVTTPQAVSIGDVRRELTFCK--KTGLQVIGVIENM 131
Cdd:cd01983    39 DYVLIDGGGGLETGllLGTIVALLALKKADEVIVVVDPELGSLLEAVKLLLALLllGIGIRPDGIVLNK 107
SIMIBI_bact_arch cd03110
bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily ...
 49-167 3.04e-03

bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily of SIMIBI superfamily. Proteins in this superfamily contain an ATP-binding domain and use energy from hydrolysis of ATP to transfer electron or ion. The specific function of this family is unknown.


Pssm-ID: 349764 [Multi-domain]  Cd Length: 246  Bit Score: 37.36  E-value: 3.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188060  49 KKHALIKQFVSDVAwgqldylVVDTPPGTsdeHMATMEALRpyrplGA---LVVTTPQAVSIGDVRRELTFCKKTGLQVi 125
Cdd:cd03110   150 RKKALERSKECDLA-------IIDGPPGT---GCPVVASIT-----GAdavLLVTEPTPSGLHDLKRAIELAKHFGIPT- 213

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1822188060 126 GVIENMSGFtcphcaectNVFSSGSGEELARLAGVPFLGSVP 167
Cdd:cd03110   214 GIVINRYDI---------NDEISEEIEDFADEEGIPLLGKIP 246
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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