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Conserved domains on  [gi|1774222196|ref|NP_001363062|]
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tetratricopeptide repeat protein 31 isoform e [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11419012)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

Gene Ontology:  GO:0005515
PubMed:  10517866|30708253

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
306-416 3.70e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 72.35  E-value: 3.70e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 306 LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 385
Cdd:COG0457    45 LYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELG 124

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1774222196 386 RFREAAAVFQETLRGGSQPDAARELRSCLLH 416
Cdd:COG0457   125 RYDEAIEAYERALELDPDDADALYNLGIALE 155
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
306-416 3.70e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 72.35  E-value: 3.70e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 306 LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 385
Cdd:COG0457    45 LYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELG 124

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1774222196 386 RFREAAAVFQETLRGGSQPDAARELRSCLLH 416
Cdd:COG0457   125 RYDEAIEAYERALELDPDDADALYNLGIALE 155
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 322-395 4.51e-07

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 52.10  E-value: 4.51e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1774222196 322 AVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQ 395
Cdd:PLN03088   21 AVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLEEYQTAKAALE 94
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 306-390 6.31e-07

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 51.91  E-value: 6.31e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 306 LAKLGTSFAQNGFYHEAVVLFTQALKLNPqDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 385
Cdd:TIGR00990 130 LKEKGNKAYRNKDFNKAIKLYSKAIECKP-DPVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLG 208


                  ....*
gi 1774222196 386 RFREA 390
Cdd:TIGR00990 209 KYADA 213
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
306-416 3.70e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 72.35  E-value: 3.70e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 306 LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 385
Cdd:COG0457    45 LYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELG 124

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1774222196 386 RFREAAAVFQETLRGGSQPDAARELRSCLLH 416
Cdd:COG0457   125 RYDEAIEAYERALELDPDDADALYNLGIALE 155
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
306-417 7.29e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.19  E-value: 7.29e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 306 LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 385
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALG 90

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1774222196 386 RFREAAAVFQETLRGGSQ-PDAARELRSCLLHL 417
Cdd:COG0457    91 RYEEALEDYDKALELDPDdAEALYNLGLALLEL 123
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 252-399 1.07e-13

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 68.83  E-value: 1.07e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 252 ARREKGLNQEPQGRGLALQKMGQEEESPPREERPQQSPKASPGLLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALK 331
Cdd:COG5010     3 ALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQ 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1774222196 332 LNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLR 399
Cdd:COG5010    83 LDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 295-399 1.11e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 68.29  E-value: 1.11e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 295 LLAAALQQSQE----LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGW 370
Cdd:COG4783    26 LLEKALELDPDnpeaFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEH 105

                          90       100
                  ....*....|....*....|....*....
gi 1774222196 371 PRGLFRLGKALMGLQRFREAAAVFQETLR 399
Cdd:COG4783   106 PEAYLRLARAYRALGRPDEAIAALEKALE 134
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
306-412 1.31e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 70.42  E-value: 1.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 306 LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 385
Cdd:COG0457    79 LNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG 158

                          90       100
                  ....*....|....*....|....*..
gi 1774222196 386 RFREAAAVFQETLRGGSQPDAARELRS 412
Cdd:COG0457   159 RYEEALELLEKLEAAALAALLAAALGE 185
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 252-417 1.54e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 73.10  E-value: 1.54e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 252 ARREKGLNQEPQGRGLALQKMGQEEESPPREerpQQSPKASPGLLAAalqqsqeLAKLGTSFAQNGFYHEAVVLFTQALK 331
Cdd:COG3914    71 AAALLLLAALLELAALLLQALGRYEEALALY---RRALALNPDNAEA-------LFNLGNLLLALGRLEEALAALRRALA 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 332 LNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLRggSQPDAArELR 411
Cdd:COG3914   141 LNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE--LDPDNA-DAH 217


                  ....*.
gi 1774222196 412 SCLLHL 417
Cdd:COG3914   218 SNLLFA 223
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
297-421 9.02e-13

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 67.63  E-value: 9.02e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 297 AAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFR 376
Cdd:COG4785    67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN 146

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1774222196 377 LGKALMGLQRFREAAAVFQETLRgGSQPDAARELRSCLLHLTLGQ 421
Cdd:COG4785   147 RGIALYYLGRYELAIADLEKALE-LDPNDPERALWLYLAERKLDP 190
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 250-421 1.16e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 67.33  E-value: 1.16e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 250 LSARREKGLNQEPQGRGLALQKMGQEEESPPREERPQQSPKASPGLLAAALQQSQELAKLGTSFAQ----NGFYHEAVVL 325
Cdd:COG3914    21 AAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALllqaLGRYEEALAL 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 326 FTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLRggSQPD 405
Cdd:COG3914   101 YRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALE--LDPD 178

                         170
                  ....*....|....*.
gi 1774222196 406 AARelrsclLHLTLGQ 421
Cdd:COG3914   179 NAE------ALNNLGN 188
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 296-412 2.45e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 61.18  E-value: 2.45e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 296 LAAALQQSQE----LAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWP 371
Cdd:COG4235     6 LRQALAANPNdaegWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1774222196 372 RGLFRLGKALMGLQRFREAAAVFQETLRGGSQPDAARELRS 412
Cdd:COG4235    86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEA 126
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 301-417 3.14e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.98  E-value: 3.14e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 301 QQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKA 380
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1774222196 381 LMGLQRFREAAAVFQETLR-GGSQPDAARELRSCLLHL 417
Cdd:COG4783    82 LLKAGDYDEALALLEKALKlDPEHPEAYLRLARAYRAL 119
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
313-408 2.67e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 57.10  E-value: 2.67e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 313 FAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALAdAQVALTLRPGWPRGLFRLGKALMGLQRFREAAA 392
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                          90
                  ....*....|....*.
gi 1774222196 393 VFQETLRggSQPDAAR 408
Cdd:COG3063    81 YLERALE--LDPSALR 94
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
330-408 4.77e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 56.94  E-value: 4.77e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1774222196 330 LKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLRggSQPDAAR 408
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALE--LDPDDAE 77
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 295-417 1.04e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.19  E-value: 1.04e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 295 LLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGL 374
Cdd:COG2956   136 LLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPAL 215

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1774222196 375 FRLGKALMGLQRFREAAAVFQETLRGGSQPDAARELRSCLLHL 417
Cdd:COG2956   216 PRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERK 258
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 295-417 1.69e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 52.81  E-value: 1.69e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 295 LLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGL 374
Cdd:COG2956   102 LLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARAL 181

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1774222196 375 FRLGKALMGLQRFREAAAVFQETLRggSQPD---AARELRSCLLHL 417
Cdd:COG2956   182 LLLAELYLEQGDYEEAIAALERALE--QDPDylpALPRLAELYEKL 225
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 321-399 3.68e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 49.23  E-value: 3.68e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1774222196 321 EAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQETLR 399
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALA 79
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 322-395 4.51e-07

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 52.10  E-value: 4.51e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1774222196 322 AVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAVFQ 395
Cdd:PLN03088   21 AVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLEEYQTAKAALE 94
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 306-390 6.31e-07

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 51.91  E-value: 6.31e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 306 LAKLGTSFAQNGFYHEAVVLFTQALKLNPqDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQ 385
Cdd:TIGR00990 130 LKEKGNKAYRNKDFNKAIKLYSKAIECKP-DPVYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLG 208


                  ....*
gi 1774222196 386 RFREA 390
Cdd:TIGR00990 209 KYADA 213
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 295-408 7.77e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.50  E-value: 7.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 295 LLAAALQQSQELAKLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGL 374
Cdd:COG2956    68 LLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAY 147

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1774222196 375 FRLGKALMGLQRFREAAAVFQETLRggSQPDAAR 408
Cdd:COG2956   148 CELAELYLEQGDYDEAIEALEKALK--LDPDCAR 179
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 309-368 1.12e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.72  E-value: 1.12e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 309 LGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRP 368
Cdd:COG5010    94 LALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 295-415 2.70e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 45.88  E-value: 2.70e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 295 LLAAALQQSQELAKlGTSFAQNGFYHEAVVLFTQALKLNPQD---HRLFGNrsfCHERLGQPAWALADAQVALTLRPGWP 371
Cdd:COG2956     1 LLLPVAAALGWYFK-GLNYLLNGQPDKAIDLLEEALELDPETveaHLALGN---LYRRRGEYDRAIRIHQKLLERDPDRA 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1774222196 372 RGLFRLGKALMGLQRFREAAAVFQETLR-GGSQPDAARELRSCLL 415
Cdd:COG2956    77 EALLELAQDYLKAGLLDRAEELLEKLLElDPDDAEALRLLAEIYE 121
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 309-368 5.30e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.26  E-value: 5.30e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 309 LGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRP 368
Cdd:COG4783    78 LGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
240-436 5.54e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 44.61  E-value: 5.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 240 LALRKVGDWPlSARR--EKGLNQEPQ------GRGLALQKMGQEEesppreerpqqspKASPgLLAAALQQSQELAK--- 308
Cdd:COG0457    50 LAYLRLGRYE-EALAdyEQALELDPDdaealnNLGLALQALGRYE-------------EALE-DYDKALELDPDDAEaly 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 309 -LGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRF 387
Cdd:COG0457   115 nLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAE 194

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1774222196 388 REAAAVFQETLRGGSQPDAARELRSCLLHLTLGQRGGICAPPLSPGALQ 436
Cdd:COG0457   195 VLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQY 243
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 312-409 9.06e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.90  E-value: 9.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 312 SFAQNGFYHEAVVLFTQALKLNPqDHRLFGNRSF----CHERLGQPAWALADAQVALTLRPGW---PRGLFRLGKALMGL 384
Cdd:COG1729     2 ALLKAGDYDEAIAAFKAFLKRYP-NSPLAPDALYwlgeAYYALGDYDEAAEAFEKLLKRYPDSpkaPDALLKLGLSYLEL 80

                          90       100
                  ....*....|....*....|....*
gi 1774222196 385 QRFREAAAVFQETLRGGSQPDAARE 409
Cdd:COG1729    81 GDYDKARATLEELIKKYPDSEAAKE 105
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 295-410 1.38e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.95  E-value: 1.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 295 LLAAALQQSQELA----KLGTSFAQNGFYHEAVVLFTQALKLNPQDHRLFGNRSFCHERLGQPAWALADAQVALTLRPGW 370
Cdd:COG2956    30 LLEEALELDPETVeahlALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDD 109

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1774222196 371 PRGLFRLGKALMGLQRFREAAAVFQETLR-GGSQPDAAREL 410
Cdd:COG2956   110 AEALRLLAEIYEQEGDWEKAIEVLERLLKlGPENAHAYCEL 150
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
346-399 2.47e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.15  E-value: 2.47e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1774222196 346 CHERLGQPAWALADAQVALTLRPGWPRGLFRLGKALMGLQRFREAAAvFQETLR 399
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALK 53
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 290-417 4.78e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 39.12  E-value: 4.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1774222196 290 KASPGLLAAALQQsqelaklgtsFAQNGFYHEAVVLFTQALKLNPQDH--RLFGNRsfcheRLGQPAWALADAQVALTLR 367
Cdd:COG3071   190 RRDPELAAAYARA----------LIALGDHDEAERLLREALKRQWDPRlvRLYGRL-----QGGDPAKQLKRAEKWLKKH 254

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1774222196 368 PGWPRGLFRLGKALMGLQRFREAAAVFQETLRGGSQPDAARELRSCLLHL 417
Cdd:COG3071   255 PNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPSAEAYAELARLLEQL 304
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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