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Conserved domains on  [gi|1327850556|ref|NP_001346692|]
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leucine-rich repeat-containing protein 40 isoform c [Mus musculus]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
PubMed:  11751054|7583641

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
17-242 3.72e-26

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 110.02  E-value: 3.72e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  17 LKILPEEITSLKNLRTLHLQHNeltcipEGFEHLSCLEDLDLSSNRLATVPADFALLSSLLRLNLSSNQLKNLPAEISRM 96
Cdd:COG4886    85 LLLGLTDLGDLTNLTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNL 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  97 KRLKHLDCDANLLETVPPDVGSMESLELLYLRRNKLRVLP-EFPSCRQLKELHLAENQIEKLGAEhLQHLQAILVLDLRG 175
Cdd:COG4886   159 TNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPePLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSN 237

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1327850556 176 NKLRSVPeEMALLQSLERLDLSNNDISSLPCSLGNLHLKFLALEGNPLRTIRREIIAKGTQEVLKYL 242
Cdd:COG4886   238 NQLTDLP-ELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLL 303
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
194-455 4.25e-20

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 92.30  E-value: 4.25e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 194 LDLSNNDISSLPCSLGNLHLKFLALEGNPLRTIRREIIAKGTQEVLKYLRSKIKDDRTNQNDSVPETAMTLPSEARVNIH 273
Cdd:COG4886    14 LLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLG 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 274 AIATLKLLDYSDKQATlipddlfdaTKTTLITSINFSKNQLCEIPQRIVELKEMVlDINLSFNKLSFISHELCLLQKLTF 353
Cdd:COG4886    94 DLTNLTELDLSGNEEL---------SNLTNLESLDLSGNQLTDLPEELANLTNLK-ELDLSNNQLTDLPEPLGNLTNLKS 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 354 LDLRNNFLSSLPEEMSSLTKLQTINLSFNRFKVFPEVLYRISTLEAVLISNNQVGSVdPQKMKLMENLNTLDLQNNDLLQ 433
Cdd:COG4886   164 LDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTD 242

                         250       260
                  ....*....|....*....|..
gi 1327850556 434 IpPELGNCVQLRTLLLDGNPFR 455
Cdd:COG4886   243 L-PELGNLTNLEELDLSNNQLT 263
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
17-242 3.72e-26

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 110.02  E-value: 3.72e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  17 LKILPEEITSLKNLRTLHLQHNeltcipEGFEHLSCLEDLDLSSNRLATVPADFALLSSLLRLNLSSNQLKNLPAEISRM 96
Cdd:COG4886    85 LLLGLTDLGDLTNLTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNL 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  97 KRLKHLDCDANLLETVPPDVGSMESLELLYLRRNKLRVLP-EFPSCRQLKELHLAENQIEKLGAEhLQHLQAILVLDLRG 175
Cdd:COG4886   159 TNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPePLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSN 237

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1327850556 176 NKLRSVPeEMALLQSLERLDLSNNDISSLPCSLGNLHLKFLALEGNPLRTIRREIIAKGTQEVLKYL 242
Cdd:COG4886   238 NQLTDLP-ELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLL 303
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 20-454 1.45e-20

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 95.30  E-value: 1.45e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  20 LPEEI-TSLKNLRTLHLQHNELT-CIPEGFehLSCLEDLDLSSNRLAtvpadfallssllrlnlssnqlKNLPAEISRMK 97
Cdd:PLN00113  109 IPDDIfTTSSSLRYLNLSNNNFTgSIPRGS--IPNLETLDLSNNMLS----------------------GEIPNDIGSFS 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  98 RLKHLDCDANLLE-TVPPDVGSMESLELLYLRRNKL--RVLPEFPSCRQLKELHLAENQIEKLGAEHLQHLQAILVLDLR 174
Cdd:PLN00113  165 SLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLvgQIPRELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLV 244

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 175 GNKLR-SVPEEMALLQSLERLDLSNNDIS-SLPCSLGNL-HLKFLALEGNPLRTIRREIIAKGTQEVLKYLRSkikddrT 251
Cdd:PLN00113  245 YNNLTgPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLqKLISLDLSDNSLSGEIPELVIQLQNLEILHLFS------N 318

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 252 NQNDSVPETAMTLP-------------SEARVNIHAIATLKLLDYSDKQAT-LIPDDLFDATKttLITSINFSKNQLCEI 317
Cdd:PLN00113  319 NFTGKIPVALTSLPrlqvlqlwsnkfsGEIPKNLGKHNNLTVLDLSTNNLTgEIPEGLCSSGN--LFKLILFSNSLEGEI 396

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 318 PQRIVELKEMvLDINLSFNKLSF-ISHELCLLQKLTFLDLR-NNFLSSLPEEMSSLTKLQTINLSFNRFKVFPEVLYRIS 395
Cdd:PLN00113  397 PKSLGACRSL-RRVRLQDNSFSGeLPSEFTKLPLVYFLDISnNNLQGRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSK 475

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 396 TLEAVLISNNQVGSVDPQKMKLMENLNTLDLQNNDLL-QIPPELGNCVQLRTLLLDGNPF 454
Cdd:PLN00113  476 RLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVSLDLSHNQL 535
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
194-455 4.25e-20

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 92.30  E-value: 4.25e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 194 LDLSNNDISSLPCSLGNLHLKFLALEGNPLRTIRREIIAKGTQEVLKYLRSKIKDDRTNQNDSVPETAMTLPSEARVNIH 273
Cdd:COG4886    14 LLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLG 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 274 AIATLKLLDYSDKQATlipddlfdaTKTTLITSINFSKNQLCEIPQRIVELKEMVlDINLSFNKLSFISHELCLLQKLTF 353
Cdd:COG4886    94 DLTNLTELDLSGNEEL---------SNLTNLESLDLSGNQLTDLPEELANLTNLK-ELDLSNNQLTDLPEPLGNLTNLKS 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 354 LDLRNNFLSSLPEEMSSLTKLQTINLSFNRFKVFPEVLYRISTLEAVLISNNQVGSVdPQKMKLMENLNTLDLQNNDLLQ 433
Cdd:COG4886   164 LDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTD 242

                         250       260
                  ....*....|....*....|..
gi 1327850556 434 IpPELGNCVQLRTLLLDGNPFR 455
Cdd:COG4886   243 L-PELGNLTNLEELDLSNNQLT 263
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 22-228 2.44e-14

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 72.13  E-value: 2.44e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  22 EEITSLKNLRTLHLQHNELTCIpEGFEHLSCLEDLDLSSNRlatvpadfallssllrlnlssnqlknlpaeISRMKRLKH 101
Cdd:cd21340    18 DNLSLCKNLKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQ------------------------------IEKIENLEN 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 102 LdcdanlletvppdvgsmESLELLYLRRNKLRVLPEFPSCRQLKELHLaENQieKLGAEH--------LQHLQAIL-VLD 172
Cdd:cd21340    67 L-----------------VNLKKLYLGGNRISVVEGLENLTNLEELHI-ENQ--RLPPGEkltfdprsLAALSNSLrVLN 126

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 173 LRGNKLRSVpEEMALLQSLERLDLSNNDISSLP---CSLGNL-HLKFLALEGNPLRTIRR 228
Cdd:cd21340   127 ISGNNIDSL-EPLAPLRNLEQLDASNNQISDLEellDLLSSWpSLRELDLTGNPVCKKPK 185
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
228-478 5.15e-09

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 58.55  E-value: 5.15e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 228 REIIAKGTQEVLKYLRSKIKDDR---TNQNDSVPETAMTLPSEAR------VNIHAiaTLKLLDYSDKQATLIPDDLFDA 298
Cdd:PRK15370  165 REEAVQRMRDCLKNNKTELRLKIlglTTIPACIPEQITTLILDNNelkslpENLQG--NIKTLYANSNQLTSIPATLPDT 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 299 tkttlITSINFSKNQLCEIPQRiveLKEMVLDINLSFNKLSFISHELCllQKLTFLDLRNNFLSSLPEEM-SSLTKLQTI 377
Cdd:PRK15370  243 -----IQEMELSINRITELPER---LPSALQSLDLFHNKISCLPENLP--EELRYLSVYDNSIRTLPAHLpSGITHLNVQ 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 378 NlsfNRFKVFPEVL-YRISTLEAvliSNNQVGSVdPQkmKLMENLNTLDLQNNDLLQIPPELGNCVQlrTLLLDGN---- 452
Cdd:PRK15370  313 S---NSLTALPETLpPGLKTLEA---GENALTSL-PA--SLPPELQVLDVSKNQITVLPETLPPTIT--TLDVSRNaltn 381

                         250       260
                  ....*....|....*....|....*..
gi 1327850556 453 -PFRVPRAAILMKGTAAVLEYLRDRIP 478
Cdd:PRK15370  382 lPENLPAALQIMQASRNNLVRLPESLP 408
LRR_8 pfam13855
Leucine rich repeat;
142-201 3.28e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 47.13  E-value: 3.28e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1327850556 142 RQLKELHLAENQIEKLGAEHLQHLQAILVLDLRGNKLRSV-PEEMALLQSLERLDLSNNDI 201
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 336-454 1.96e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 42.85  E-value: 1.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 336 NKLSFISHeLCLLQKLTFLDLRNNFLSSLpEEMSSLTKLQTINLSFNRFKVFpEVLYRISTLE----------------- 398
Cdd:cd21340    34 NKITKIEN-LEFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV-EGLENLTNLEelhienqrlppgekltf 110

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1327850556 399 ------------AVL-ISNNQVGSVDPqkMKLMENLNTLDLQNN---DLLQIPPELGNCVQLRTLLLDGNPF 454
Cdd:cd21340   111 dprslaalsnslRVLnISGNNIDSLEP--LAPLRNLEQLDASNNqisDLEELLDLLSSWPSLRELDLTGNPV 180
LRR_8 pfam13855
Leucine rich repeat;
331-384 2.71e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.96  E-value: 2.71e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1327850556 331 INLSFNKLSFISHELCL-LQKLTFLDLRNNFLSSL-PEEMSSLTKLQTINLSFNRF 384
Cdd:pfam13855   6 LDLSNNRLTSLDDGAFKgLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
17-242 3.72e-26

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 110.02  E-value: 3.72e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  17 LKILPEEITSLKNLRTLHLQHNeltcipEGFEHLSCLEDLDLSSNRLATVPADFALLSSLLRLNLSSNQLKNLPAEISRM 96
Cdd:COG4886    85 LLLGLTDLGDLTNLTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNL 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  97 KRLKHLDCDANLLETVPPDVGSMESLELLYLRRNKLRVLP-EFPSCRQLKELHLAENQIEKLGAEhLQHLQAILVLDLRG 175
Cdd:COG4886   159 TNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPePLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSN 237

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1327850556 176 NKLRSVPeEMALLQSLERLDLSNNDISSLPCSLGNLHLKFLALEGNPLRTIRREIIAKGTQEVLKYL 242
Cdd:COG4886   238 NQLTDLP-ELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLL 303
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
10-324 4.77e-26

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 109.64  E-value: 4.77e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  10 LFLIHNKLKILPEEITSLKNLRTLHLQHNELTCIPEGFEHLSCLEDLDLSSNrlatvpadfallssllrlnlssnQLKNL 89
Cdd:COG4886   118 LDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNN-----------------------QLTDL 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  90 PAEISRMKRLKHLDCDANLLETVPPDVGSMESLELLYLRRNKLRVLP-EFPSCRQLKELHLAENQIEKLgaEHLQHLQAI 168
Cdd:COG4886   175 PEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPePLANLTNLETLDLSNNQLTDL--PELGNLTNL 252

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 169 LVLDLRGNKLRSVPEEMAlLQSLERLDLSNNDISSLPCSLGNLHLKFLALEGNPLRTIRREIIAKGTQEVLKYLRSKIKD 248
Cdd:COG4886   253 EELDLSNNQLTDLPPLAN-LTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLK 331

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1327850556 249 DRTNQNDSVPETAMTLPSEARVNIHAIATLKLLDYSDKQATLIPDDLFDATKTTLITSINFSKNQLCEIPQRIVEL 324
Cdd:COG4886   332 GLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLAL 407
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 20-454 1.45e-20

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 95.30  E-value: 1.45e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  20 LPEEI-TSLKNLRTLHLQHNELT-CIPEGFehLSCLEDLDLSSNRLAtvpadfallssllrlnlssnqlKNLPAEISRMK 97
Cdd:PLN00113  109 IPDDIfTTSSSLRYLNLSNNNFTgSIPRGS--IPNLETLDLSNNMLS----------------------GEIPNDIGSFS 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  98 RLKHLDCDANLLE-TVPPDVGSMESLELLYLRRNKL--RVLPEFPSCRQLKELHLAENQIEKLGAEHLQHLQAILVLDLR 174
Cdd:PLN00113  165 SLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLvgQIPRELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLV 244

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 175 GNKLR-SVPEEMALLQSLERLDLSNNDIS-SLPCSLGNL-HLKFLALEGNPLRTIRREIIAKGTQEVLKYLRSkikddrT 251
Cdd:PLN00113  245 YNNLTgPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLqKLISLDLSDNSLSGEIPELVIQLQNLEILHLFS------N 318

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 252 NQNDSVPETAMTLP-------------SEARVNIHAIATLKLLDYSDKQAT-LIPDDLFDATKttLITSINFSKNQLCEI 317
Cdd:PLN00113  319 NFTGKIPVALTSLPrlqvlqlwsnkfsGEIPKNLGKHNNLTVLDLSTNNLTgEIPEGLCSSGN--LFKLILFSNSLEGEI 396

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 318 PQRIVELKEMvLDINLSFNKLSF-ISHELCLLQKLTFLDLR-NNFLSSLPEEMSSLTKLQTINLSFNRFKVFPEVLYRIS 395
Cdd:PLN00113  397 PKSLGACRSL-RRVRLQDNSFSGeLPSEFTKLPLVYFLDISnNNLQGRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSK 475

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 396 TLEAVLISNNQVGSVDPQKMKLMENLNTLDLQNNDLL-QIPPELGNCVQLRTLLLDGNPF 454
Cdd:PLN00113  476 RLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVSLDLSHNQL 535
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
194-455 4.25e-20

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 92.30  E-value: 4.25e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 194 LDLSNNDISSLPCSLGNLHLKFLALEGNPLRTIRREIIAKGTQEVLKYLRSKIKDDRTNQNDSVPETAMTLPSEARVNIH 273
Cdd:COG4886    14 LLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLG 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 274 AIATLKLLDYSDKQATlipddlfdaTKTTLITSINFSKNQLCEIPQRIVELKEMVlDINLSFNKLSFISHELCLLQKLTF 353
Cdd:COG4886    94 DLTNLTELDLSGNEEL---------SNLTNLESLDLSGNQLTDLPEELANLTNLK-ELDLSNNQLTDLPEPLGNLTNLKS 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 354 LDLRNNFLSSLPEEMSSLTKLQTINLSFNRFKVFPEVLYRISTLEAVLISNNQVGSVdPQKMKLMENLNTLDLQNNDLLQ 433
Cdd:COG4886   164 LDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTD 242

                         250       260
                  ....*....|....*....|..
gi 1327850556 434 IpPELGNCVQLRTLLLDGNPFR 455
Cdd:COG4886   243 L-PELGNLTNLEELDLSNNQLT 263
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
272-454 6.26e-20

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 91.92  E-value: 6.26e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 272 IHAIATLKLLDYSDKQATLIPDDLFDATKttlITSINFSKNQLCEIPQRIVELKEMVlDINLSFNKLSFISHELCLLQKL 351
Cdd:COG4886   109 LSNLTNLESLDLSGNQLTDLPEELANLTN---LKELDLSNNQLTDLPEPLGNLTNLK-SLDLSNNQLTDLPEELGNLTNL 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 352 TFLDLRNNFLSSLPEEMSSLTKLQTINLSFNRFKVFPEVLYRISTLEAVLISNNQVGSVDpqKMKLMENLNTLDLQNNDL 431
Cdd:COG4886   185 KELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP--ELGNLTNLEELDLSNNQL 262

                         170       180
                  ....*....|....*....|...
gi 1327850556 432 LQIPPeLGNCVQLRTLLLDGNPF 454
Cdd:COG4886   263 TDLPP-LANLTNLKTLDLSNNQL 284
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
54-450 3.39e-17

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 83.44  E-value: 3.39e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  54 EDLDLSSNRLATVPADFALLSSLLRLNLSSNQLKNLPAEISRMKRLKHLDCDANLLETVPPDVGSMESLELLYLRRNKLR 133
Cdd:COG4886     8 LTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 134 VLPEFPSCRQLKELHLAENqieklgaEHLQHLQAILVLDLRGNKLRSVPEEMALLQSLERLDLSNNDISSLPCSLGNL-H 212
Cdd:COG4886    88 GLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLtN 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 213 LKFLALEGNPLRTIRREiiakgtqevlkylrskikddrtnqndsvpetamtlpsearvnihaIATLKLLdysdkqatlip 292
Cdd:COG4886   161 LKSLDLSNNQLTDLPEE---------------------------------------------LGNLTNL----------- 184

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 293 ddlfdatkttliTSINFSKNQLCEIPQRIVELKEMVlDINLSFNKLSFISHELCLLQKLTFLDLRNNFLSSLPeEMSSLT 372
Cdd:COG4886   185 ------------KELDLSNNQITDLPEPLGNLTNLE-ELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLT 250

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1327850556 373 KLQTINLSFNRFKVFPEvLYRISTLEAVLISNNQVGSVDPQKMKLMENLNTLDLQNNDLLQIPPELGNCVQLRTLLLD 450
Cdd:COG4886   251 NLEELDLSNNQLTDLPP-LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLL 327
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 22-228 2.44e-14

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 72.13  E-value: 2.44e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  22 EEITSLKNLRTLHLQHNELTCIpEGFEHLSCLEDLDLSSNRlatvpadfallssllrlnlssnqlknlpaeISRMKRLKH 101
Cdd:cd21340    18 DNLSLCKNLKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQ------------------------------IEKIENLEN 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 102 LdcdanlletvppdvgsmESLELLYLRRNKLRVLPEFPSCRQLKELHLaENQieKLGAEH--------LQHLQAIL-VLD 172
Cdd:cd21340    67 L-----------------VNLKKLYLGGNRISVVEGLENLTNLEELHI-ENQ--RLPPGEkltfdprsLAALSNSLrVLN 126

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 173 LRGNKLRSVpEEMALLQSLERLDLSNNDISSLP---CSLGNL-HLKFLALEGNPLRTIRR 228
Cdd:cd21340   127 ISGNNIDSL-EPLAPLRNLEQLDASNNQISDLEellDLLSSWpSLRELDLTGNPVCKKPK 185
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 3-452 6.19e-14

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 74.50  E-value: 6.19e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556   3 SDSCLPLLFLIHNKLK-ILPEEITSLKNLRTLHLQHNELTC-IPEGFEHLSCLEDLDLSSNRL-ATVPADFALLSSLLRL 79
Cdd:PLN00113  138 SIPNLETLDLSNNMLSgEIPNDIGSFSSLKVLDLGGNVLVGkIPNSLTNLTSLEFLTLASNQLvGQIPRELGQMKSLKWI 217

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  80 NLSSNQLK-NLPAEISRMKRLKHLD-CDANLLETVPPDVGSMESLELLYLRRNKL--RVLPEFPSCRQLKELHLAEN--- 152
Cdd:PLN00113  218 YLGYNNLSgEIPYEIGGLTSLNHLDlVYNNLTGPIPSSLGNLKNLQYLFLYQNKLsgPIPPSIFSLQKLISLDLSDNsls 297

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 153 --------QIEKLGAEHL-------------QHLQAILVLDLRGNKLR-SVPEEMALLQSLERLDLSNNDISS-LP---C 206
Cdd:PLN00113  298 geipelviQLQNLEILHLfsnnftgkipvalTSLPRLQVLQLWSNKFSgEIPKNLGKHNNLTVLDLSTNNLTGeIPeglC 377

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 207 SLGNLHLKFL---ALEGNplrtirreiIAKGTQEVLKYLRSKIKDDrtNQNDSVPETAMTLPseaRVNIHAIATLKLLDY 283
Cdd:PLN00113  378 SSGNLFKLILfsnSLEGE---------IPKSLGACRSLRRVRLQDN--SFSGELPSEFTKLP---LVYFLDISNNNLQGR 443

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 284 SDKQATLIPD-------------DLFDATKTTLITSINFSKNQLCE-IPQRIVELKEMvLDINLSFNKLSfishelcllq 349
Cdd:PLN00113  444 INSRKWDMPSlqmlslarnkffgGLPDSFGSKRLENLDLSRNQFSGaVPRKLGSLSEL-MQLKLSENKLS---------- 512

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 350 kltfldlrnnflSSLPEEMSSLTKLQTINLSFNRFK-VFPEVLYRISTLEAVLISNNQVGSVDPQKMKLMENLNTLDLQN 428
Cdd:PLN00113  513 ------------GEIPDELSSCKKLVSLDLSHNQLSgQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISH 580

                         490       500
                  ....*....|....*....|....
gi 1327850556 429 NDLLQIPPELGNCVQLRTLLLDGN 452
Cdd:PLN00113  581 NHLHGSLPSTGAFLAINASAVAGN 604
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
10-208 4.14e-12

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 68.57  E-value: 4.14e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  10 LFLIHNKLKILPEEITSlkNLRTLHLQHNELTCIPEGFEhlSCLEDLDLSSNRLATVPadfallssllrlnlssnqlKNL 89
Cdd:PRK15370  204 LILDNNELKSLPENLQG--NIKTLYANSNQLTSIPATLP--DTIQEMELSINRITELP-------------------ERL 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  90 PAEisrmkrLKHLDCDANLLETVPPDVGsmESLELLYLRRNKLRVLPE-FPScrQLKELHLAENQIEKLGAEHLQHLQaI 168
Cdd:PRK15370  261 PSA------LQSLDLFHNKISCLPENLP--EELRYLSVYDNSIRTLPAhLPS--GITHLNVQSNSLTALPETLPPGLK-T 329

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1327850556 169 LVLDlrGNKLRSVPEemALLQSLERLDLSNNDISSLPCSL 208
Cdd:PRK15370  330 LEAG--ENALTSLPA--SLPPELQVLDVSKNQITVLPETL 365
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
15-293 8.52e-10

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 61.25  E-value: 8.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  15 NKLKILPEEITSLknLRTLHLQHNELTCIPEGFEhlSCLEDLDLSSNRLATVPAdfallssllrlnlssnqlkNLPAEIS 94
Cdd:PRK15370  251 NRITELPERLPSA--LQSLDLFHNKISCLPENLP--EELRYLSVYDNSIRTLPA-------------------HLPSGIT 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  95 rmkrlkHLDCDANLL----ETVPPDvgsmesLELLYLRRNKLRVLPE-FPScrQLKELHLAENQIEKLgAEHLQhlQAIL 169
Cdd:PRK15370  308 ------HLNVQSNSLtalpETLPPG------LKTLEAGENALTSLPAsLPP--ELQVLDVSKNQITVL-PETLP--PTIT 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 170 VLDLRGNKLRSVPEEmaLLQSLERLDLSNNDISSLPCSLGNL-----HLKFLALEGNPL--RTIR--------------R 228
Cdd:PRK15370  371 TLDVSRNALTNLPEN--LPAALQIMQASRNNLVRLPESLPHFrgegpQPTRIIVEYNPFseRTIQnmqrlmssvgyqgpR 448

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1327850556 229 EIIAKGTQEVLKYLR----------SKIKDDRTNQNDSVpetamtlpsEARVNIHAIATlkLLDY-SDKQATLIPD 293
Cdd:PRK15370  449 VLFAMGDFSIVRVTRplhqavqgwlTNLEEEDVNQWRAF---------ETEVNAAAFSM--FLDRlSDTQNTRHPD 513
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
5-167 4.11e-09

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 58.94  E-value: 4.11e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556   5 SCLPLLFLIHNKLKILPEEITslKNLRTLHLQHNELTCIPegfEHL-SCLEDLDLSSNRLATVPADFALLSSLLRLNLSS 83
Cdd:PRK15370  262 SALQSLDLFHNKISCLPENLP--EELRYLSVYDNSIRTLP---AHLpSGITHLNVQSNSLTALPETLPPGLKTLEAGENA 336

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  84 nqLKNLPAEISrmKRLKHLDCDAN----LLETVPPdvgsmeSLELLYLRRNKLRVLPE-FPSCrqLKELHLAENQIEKLg 158
Cdd:PRK15370  337 --LTSLPASLP--PELQVLDVSKNqitvLPETLPP------TITTLDVSRNALTNLPEnLPAA--LQIMQASRNNLVRL- 403


                  ....*....
gi 1327850556 159 AEHLQHLQA 167
Cdd:PRK15370  404 PESLPHFRG 412
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
228-478 5.15e-09

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 58.55  E-value: 5.15e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 228 REIIAKGTQEVLKYLRSKIKDDR---TNQNDSVPETAMTLPSEAR------VNIHAiaTLKLLDYSDKQATLIPDDLFDA 298
Cdd:PRK15370  165 REEAVQRMRDCLKNNKTELRLKIlglTTIPACIPEQITTLILDNNelkslpENLQG--NIKTLYANSNQLTSIPATLPDT 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 299 tkttlITSINFSKNQLCEIPQRiveLKEMVLDINLSFNKLSFISHELCllQKLTFLDLRNNFLSSLPEEM-SSLTKLQTI 377
Cdd:PRK15370  243 -----IQEMELSINRITELPER---LPSALQSLDLFHNKISCLPENLP--EELRYLSVYDNSIRTLPAHLpSGITHLNVQ 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 378 NlsfNRFKVFPEVL-YRISTLEAvliSNNQVGSVdPQkmKLMENLNTLDLQNNDLLQIPPELGNCVQlrTLLLDGN---- 452
Cdd:PRK15370  313 S---NSLTALPETLpPGLKTLEA---GENALTSL-PA--SLPPELQVLDVSKNQITVLPETLPPTIT--TLDVSRNaltn 381

                         250       260
                  ....*....|....*....|....*..
gi 1327850556 453 -PFRVPRAAILMKGTAAVLEYLRDRIP 478
Cdd:PRK15370  382 lPENLPAALQIMQASRNNLVRLPESLP 408
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 291-457 1.35e-08

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 57.55  E-value: 1.35e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 291 IPDDLFdaTKTTLITSINFSKNQLC-EIPQRIVELKEMvldINLSFNKLSF-ISHELCLLQKLTFLDLRNNFLSS-LPEE 367
Cdd:PLN00113  109 IPDDIF--TTSSSLRYLNLSNNNFTgSIPRGSIPNLET---LDLSNNMLSGeIPNDIGSFSSLKVLDLGGNVLVGkIPNS 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 368 MSSLTKLQTINLSFNRF-KVFPEVLYRISTLEAVLISNNQVGSVDPQKMKLMENLNTLDLQNNDLL-QIPPELGNCVQLR 445
Cdd:PLN00113  184 LTNLTSLEFLTLASNQLvGQIPRELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTgPIPSSLGNLKNLQ 263

                         170
                  ....*....|..
gi 1327850556 446 TLLLDGNPFRVP 457
Cdd:PLN00113  264 YLFLYQNKLSGP 275
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
10-232 6.91e-08

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 55.17  E-value: 6.91e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  10 LFLIHNKLKILPEEITSLKNLRTLHLQHNELTCIPEGfehlscLEDLDLSSNRLATVPadfALLSSLLRLNLSSNQLKNL 89
Cdd:PRK15387  267 LSIFSNPLTHLPALPSGLCKLWIFGNQLTSLPVLPPG------LQELSVSDNQLASLP---ALPSELCKLWAYNNQLTSL 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  90 PAEISRMKRLKHLDCDANLLETVPPDvgsmesLELLYLRRNKLRVLPEFPScrQLKELHLAENQIEKLGAEHlQHLQAIL 169
Cdd:PRK15387  338 PTLPSGLQELSVSDNQLASLPTLPSE------LYKLWAYNNRLTSLPALPS--GLKELIVSGNRLTSLPVLP-SELKELM 408

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 170 VldlRGNKLRSVPeemALLQSLERLDLSNNDISSLPCSLgnLHLK---FLALEGNPL--RTIR--REIIA 232
Cdd:PRK15387  409 V---SGNRLTSLP---MLPSGLLSLSVYRNQLTRLPESL--IHLSsetTVNLEGNPLseRTLQalREITS 470
LRR_8 pfam13855
Leucine rich repeat;
142-201 3.28e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 47.13  E-value: 3.28e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1327850556 142 RQLKELHLAENQIEKLGAEHLQHLQAILVLDLRGNKLRSV-PEEMALLQSLERLDLSNNDI 201
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 17-245 2.43e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 49.28  E-value: 2.43e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  17 LKILPEEITSLKNLRTLHLQHNELTCIP-------EGFEHLSCLEDLDLSSNRLAtvpadfALLSSLLRLNLSSNQLKNL 89
Cdd:cd00116    40 AKALASALRPQPSLKELCLSLNETGRIPrglqsllQGLTKGCGLQELDLSDNALG------PDGCGVLESLLRSSSLQEL 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  90 PAEISRMKRLKhldcdANLLETVPPDVGsmESLELLYLRRNKL------RVLPEFPSCRQLKELHLAENQIEKLGAEHL- 162
Cdd:cd00116   114 KLNNNGLGDRG-----LRLLAKGLKDLP--PALEKLVLGRNRLegasceALAKALRANRDLKELNLANNGIGDAGIRALa 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 163 ---QHLQAILVLDLRGNKLRS-----VPEEMALLQSLERLDLSNNDISSLPCS-------LGNLHLKFLALEGNplrtir 227
Cdd:cd00116   187 eglKANCNLEVLDLNNNGLTDegasaLAETLASLKSLEVLNLGDNNLTDAGAAalasallSPNISLLTLSLSCN------ 260

                         250
                  ....*....|....*...
gi 1327850556 228 rEIIAKGTQEVLKYLRSK 245
Cdd:cd00116   261 -DITDDGAKDLAEVLAEK 277
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 28-219 3.10e-06

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 49.87  E-value: 3.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556   28 KNLRTLHLQHNELTCIPEGFEHLSCLEDLDL-SSNRLATVPADFALLSSLLRLNLSSNQLKNLPAEISRMKRLKHLD--- 103
Cdd:PLN03210   611 ENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLrGSKNLKEIPDLSMATNLETLKLSDCSSLVELPSSIQYLNKLEDLDmsr 690

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  104 CDAnlLETVPPDVgSMESLELLYLRR-NKLRVLPEFPScrQLKELHLAENQIEKLGAE-HLQHLQAILVLDLRGNKL--R 179
Cdd:PLN03210   691 CEN--LEILPTGI-NLKSLYRLNLSGcSRLKSFPDIST--NISWLDLDETAIEEFPSNlRLENLDELILCEMKSEKLweR 765

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1327850556  180 SVPEE--MALLQ-SLERLDLSNN-DISSLPCSLGNLH-LKFLALE 219
Cdd:PLN03210   766 VQPLTplMTMLSpSLTRLFLSDIpSLVELPSSIQNLHkLEHLEIE 810
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
20-274 2.51e-05

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 47.08  E-value: 2.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  20 LPEEITslknlrTLHLQHNELTCIPEGFEHLSCLEdldLSSNRLATVPAdfaLLSSLLRLNLSSNQLKNLPAEISRMKRL 99
Cdd:PRK15387  220 LPAHIT------TLVIPDNNLTSLPALPPELRTLE---VSGNQLTSLPV---LPPGLLELSIFSNPLTHLPALPSGLCKL 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 100 KHLDCDANLLETVPP----------DVGSMESL--EL--LYLRRNKLRVLPEFPScrQLKELHLAENQIEKLGA--EHLQ 163
Cdd:PRK15387  288 WIFGNQLTSLPVLPPglqelsvsdnQLASLPALpsELckLWAYNNQLTSLPTLPS--GLQELSVSDNQLASLPTlpSELY 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 164 HLQAIlvldlrGNKLRSVPeemALLQSLERLDLSNNDISSLPCSLGnlHLKFLALEGNPLRTIrrEIIAKGTQEVLKYlr 243
Cdd:PRK15387  366 KLWAY------NNRLTSLP---ALPSGLKELIVSGNRLTSLPVLPS--ELKELMVSGNRLTSL--PMLPSGLLSLSVY-- 430

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1327850556 244 skikddrTNQNDSVPETAMTLPSEARVNIHA 274
Cdd:PRK15387  431 -------RNQLTRLPESLIHLSSETTVNLEG 454
LRR_8 pfam13855
Leucine rich repeat;
121-178 5.40e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.97  E-value: 5.40e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 121 SLELLYLRRNKLRVLPE--FPSCRQLKELHLAENQIEKLGAEHLQHLQAILVLDLRGNKL 178
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
10-63 5.79e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.97  E-value: 5.79e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1327850556  10 LFLIHNKLKILPEEI-TSLKNLRTLHLQHNELTCI-PEGFEHLSCLEDLDLSSNRL 63
Cdd:pfam13855   6 LDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 354-459 5.87e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 45.58  E-value: 5.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 354 LDLRNNFLSS-LPEEMSSLTKLQTINLSFNRFKvfpevlyristleavlisnnqvGSVdPQKMKLMENLNTLDLQNNDLL 432
Cdd:PLN03150  423 LGLDNQGLRGfIPNDISKLRHLQSINLSGNSIR----------------------GNI-PPSLGSITSLEVLDLSYNSFN 479

                          90       100       110
                  ....*....|....*....|....*....|
gi 1327850556 433 -QIPPELGNCVQLRTLLLDGNPF--RVPRA 459
Cdd:PLN03150  480 gSIPESLGQLTSLRILNLNGNSLsgRVPAA 509
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 354-464 6.05e-05

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 45.61  E-value: 6.05e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 354 LDLRNNFLS-SLPEEMSSLT-KLQTINLSFNRFKvFPEVLYRISTLEAVLISNNQVGSVDPQKMKLMENLNTLDLQNNDL 431
Cdd:PLN00113   98 INLSNNQLSgPIPDDIFTTSsSLRYLNLSNNNFT-GSIPRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVL 176

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1327850556 432 L-QIPPELGNCVQLRTLLLDGNPF--RVPRAAILMK 464
Cdd:PLN00113  177 VgKIPNSLTNLTSLEFLTLASNQLvgQIPRELGQMK 212
PLN03150 PLN03150
hypothetical protein; Provisional
 137-213 1.03e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 44.81  E-value: 1.03e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1327850556 137 EFPSCRQLKELHLAENQIEKLGAEHLQHLQAILVLDLRGNKLR-SVPEEMALLQSLERLDLSNNDISS-LPCSLGNLHL 213
Cdd:PLN03150  437 DISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSLSGrVPAALGGRLL 515
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 143-237 1.63e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 44.01  E-value: 1.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 143 QLKELHLAENQIEKLGA----EHLQHLQAILVLDLRGNKLrSVPEEMALLQSL------ERLDLSNNDIS-----SLPCS 207
Cdd:COG5238   209 TVTTLWLKRNPIGDEGAeilaEALKGNKSLTTLDLSNNQI-GDEGVIALAEALknnttvETLYLSGNQIGaegaiALAKA 287

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1327850556 208 L-GNLHLKFLALEGNPLRTIRREIIAKGTQE 237
Cdd:COG5238   288 LqGNTTLTSLDLSVNRIGDEGAIALAEGLQG 318
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 125-382 1.93e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 42.85  E-value: 1.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 125 LYLRRNKLRVLPEFPSCRQLKELHLAENQIEKLgaEHLQHLQAILVLDLRGNKLRSVpEEMALLQSLERLDLSNNDISSL 204
Cdd:cd21340     7 LYLNDKNITKIDNLSLCKNLKVLYLYDNKITKI--ENLEFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 205 pCSLGNLH-LKFLALEgnplrtirreiiakgtqevlkylrskikddrtNQNDSvPETAMTLPSEArvnIHAIA-TLKLLd 282
Cdd:cd21340    84 -EGLENLTnLEELHIE--------------------------------NQRLP-PGEKLTFDPRS---LAALSnSLRVL- 125

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 283 ysdkqatlipddlfdatkttlitsinfsknqlceipqrivelkemvldiNLSFNKLSFIShELCLLQKLTFLDLRNNFLS 362
Cdd:cd21340   126 -------------------------------------------------NISGNNIDSLE-PLAPLRNLEQLDASNNQIS 155

                         250       260
                  ....*....|....*....|...
gi 1327850556 363 SLPE---EMSSLTKLQTINLSFN 382
Cdd:cd21340   156 DLEElldLLSSWPSLRELDLTGN 178
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 336-454 1.96e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 42.85  E-value: 1.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 336 NKLSFISHeLCLLQKLTFLDLRNNFLSSLpEEMSSLTKLQTINLSFNRFKVFpEVLYRISTLE----------------- 398
Cdd:cd21340    34 NKITKIEN-LEFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV-EGLENLTNLEelhienqrlppgekltf 110

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1327850556 399 ------------AVL-ISNNQVGSVDPqkMKLMENLNTLDLQNN---DLLQIPPELGNCVQLRTLLLDGNPF 454
Cdd:cd21340   111 dprslaalsnslRVLnISGNNIDSLEP--LAPLRNLEQLDASNNqisDLEELLDLLSSWPSLRELDLTGNPV 180
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 10-194 1.01e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 41.31  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  10 LFLIHNKL-----KILPEEITSLKNLRTLHLQHNELT-----CIPEGFEHLSCLEDLDLSSNRLATVPADFallssllrl 79
Cdd:COG5238   269 LYLSGNQIgaegaIALAKALQGNTTLTSLDLSVNRIGdegaiALAEGLQGNKTLHTLNLAYNGIGAQGAIA--------- 339

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556  80 nlssnqlknLPAEISRMKRLKHLDCDANLLetvppdvgSMESLELL--YLRRNKlrvlpefpscrQLKELHLAENQIEKL 157
Cdd:COG5238   340 ---------LAKALQENTTLHSLDLSDNQI--------GDEGAIALakYLEGNT-----------TLRELNLGKNNIGKQ 391

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1327850556 158 GAEHL-QHLQAILV--LDLRGNKLRSVPEEmALLQSLERL 194
Cdd:COG5238   392 GAEALiDALQTNRLhtLILDGNLIGAEAQQ-RLEQLLERI 430
LRR_8 pfam13855
Leucine rich repeat;
331-384 2.71e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.96  E-value: 2.71e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1327850556 331 INLSFNKLSFISHELCL-LQKLTFLDLRNNFLSSL-PEEMSSLTKLQTINLSFNRF 384
Cdd:pfam13855   6 LDLSNNRLTSLDDGAFKgLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
395-454 3.71e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.58  E-value: 3.71e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1327850556 395 STLEAVLISNNQVGSVDPQKMKLMENLNTLDLQNNDLLQIPPE-LGNCVQLRTLLLDGNPF 454
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 125-382 4.56e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 39.26  E-value: 4.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 125 LYLRRNKL---RVLPEFPSCRQLKELHLAENQIEKLG----AEHLQHLQAILVLDLRGNKLRSVPEEMALLQS------- 190
Cdd:cd00116     3 LSLKGELLkteRATELLPKLLCLQVLRLEGNTLGEEAakalASALRPQPSLKELCLSLNETGRIPRGLQSLLQgltkgcg 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 191 LERLDLSNNDISSLPC----------SLGNLHLKFLALEGNPLRtirreIIAKGTQEVLKYLRSKIKDDRTNQNDSVPET 260
Cdd:cd00116    83 LQELDLSDNALGPDGCgvlesllrssSLQELKLNNNGLGDRGLR-----LLAKGLKDLPPALEKLVLGRNRLEGASCEAL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327850556 261 AMTLPsearvnihAIATLKLLDYSDKQatlIPDDLFDAtkttlitsinfsknqLCEIPQRIVELKEMVLDiNLSFNKL-- 338
Cdd:cd00116   158 AKALR--------ANRDLKELNLANNG---IGDAGIRA---------------LAEGLKANCNLEVLDLN-NNGLTDEga 210

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1327850556 339 SFISHELCLLQKLTFLDLRNNFLSS------LPEEMSSLTKLQTINLSFN 382
Cdd:cd00116   211 SALAETLASLKSLEVLNLGDNNLTDagaaalASALLSPNISLLTLSLSCN 260
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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