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Conserved domains on  [gi|1279489789|ref|NP_001345132|]
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V-type proton ATPase catalytic subunit A isoform 1 [Mus musculus]

Protein Classification

ATP synthase subunit A( domain architecture ID 11490110)

ATP synthase subunit A is the catalytic alpha chain of a V-type ATPase which produces ATP from ADP in the presence of a proton gradient across the membrane

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
V-ATPase_V1_A TIGR01042
V-type (H+)-ATPase V1, A subunit; This models eukaryotic vacuolar (H+)-ATPase that is ...
17-609 0e+00

V-type (H+)-ATPase V1, A subunit; This models eukaryotic vacuolar (H+)-ATPase that is responsible for acidifying cellular compartments. This enzyme shares extensive sequence similarity with archaeal ATP synthase. [Transport and binding proteins, Cations and iron carrying compounds]


:

Pssm-ID: 273411 [Multi-domain]  Cd Length: 591  Bit Score: 1258.50  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  17 TFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMG 96
Cdd:TIGR01042   1 EYGYIYKVSGPVVVAENMAGAAMYELVRVGHDELVGEIIRLEGDKATIQVYEETSGLTVGDPVLRTGKPLSVELGPGILG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  97 AIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDIKWEFIPsKNLRVGSHITGGDIYGIVNENSLIKHKIMLPPRNRGSV 176
Cdd:TIGR01042  81 NIFDGIQRPLKAIAEQSQSIYIPRGVNVPALDRDKKWEFTP-KKLRVGDHITGGDIYGTVFENSLIKHKIMLPPRARGTI 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 177 TYIAPPGNYDASDVVLELEFEGVKEKFSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGK 256
Cdd:TIGR01042 160 TYIAPAGNYTVDDTVLEVEFQGVKKKFSMLQTWPVRSPRPVTEKLPANTPLLTGQRVLDALFPCVQGGTTAIPGAFGCGK 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 257 TVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEY 336
Cdd:TIGR01042 240 TVISQSLSKYSNSDAIVYVGCGERGNEMAEVLMDFPELTMEVDGREESIMKRTTLVANTSNMPVAAREASIYTGITLAEY 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 337 FRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGD 416
Cdd:TIGR01042 320 FRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGSPEREGSVSIVGAVSPPGGD 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 417 FSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLV 496
Cdd:TIGR01042 400 FSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALEEFYEKFYPEFVPLRTKAKEILQEEEDLNEIVQLV 479
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 497 GKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVETTAQSDNKITWSIIREHMGE 576
Cdd:TIGR01042 480 GKDALAETDKITLEVAKLIKEDFLQQNGYTPYDRFCPFYKTVGMMRNMIAFYDLARQAVERTAQDDNKITWSIIKESLGD 559
                         570       580       590
                  ....*....|....*....|....*....|...
gi 1279489789 577 ILYKLSSMKFKDPVkDGEAKIKADYAQLLEDMQ 609
Cdd:TIGR01042 560 LLYRLSSMKFEDPS-DGEAKIKADYEKLNEDMQ 591
 
Name Accession Description Interval E-value
V-ATPase_V1_A TIGR01042
V-type (H+)-ATPase V1, A subunit; This models eukaryotic vacuolar (H+)-ATPase that is ...
17-609 0e+00

V-type (H+)-ATPase V1, A subunit; This models eukaryotic vacuolar (H+)-ATPase that is responsible for acidifying cellular compartments. This enzyme shares extensive sequence similarity with archaeal ATP synthase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273411 [Multi-domain]  Cd Length: 591  Bit Score: 1258.50  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  17 TFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMG 96
Cdd:TIGR01042   1 EYGYIYKVSGPVVVAENMAGAAMYELVRVGHDELVGEIIRLEGDKATIQVYEETSGLTVGDPVLRTGKPLSVELGPGILG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  97 AIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDIKWEFIPsKNLRVGSHITGGDIYGIVNENSLIKHKIMLPPRNRGSV 176
Cdd:TIGR01042  81 NIFDGIQRPLKAIAEQSQSIYIPRGVNVPALDRDKKWEFTP-KKLRVGDHITGGDIYGTVFENSLIKHKIMLPPRARGTI 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 177 TYIAPPGNYDASDVVLELEFEGVKEKFSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGK 256
Cdd:TIGR01042 160 TYIAPAGNYTVDDTVLEVEFQGVKKKFSMLQTWPVRSPRPVTEKLPANTPLLTGQRVLDALFPCVQGGTTAIPGAFGCGK 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 257 TVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEY 336
Cdd:TIGR01042 240 TVISQSLSKYSNSDAIVYVGCGERGNEMAEVLMDFPELTMEVDGREESIMKRTTLVANTSNMPVAAREASIYTGITLAEY 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 337 FRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGD 416
Cdd:TIGR01042 320 FRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGSPEREGSVSIVGAVSPPGGD 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 417 FSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLV 496
Cdd:TIGR01042 400 FSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALEEFYEKFYPEFVPLRTKAKEILQEEEDLNEIVQLV 479
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 497 GKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVETTAQSDNKITWSIIREHMGE 576
Cdd:TIGR01042 480 GKDALAETDKITLEVAKLIKEDFLQQNGYTPYDRFCPFYKTVGMMRNMIAFYDLARQAVERTAQDDNKITWSIIKESLGD 559
                         570       580       590
                  ....*....|....*....|....*....|...
gi 1279489789 577 ILYKLSSMKFKDPVkDGEAKIKADYAQLLEDMQ 609
Cdd:TIGR01042 560 LLYRLSSMKFEDPS-DGEAKIKADYEKLNEDMQ 591
NtpA COG1155
Archaeal/vacuolar-type H+-ATPase catalytic subunit A/Vma1 [Energy production and conversion]; ...
15-615 0e+00

Archaeal/vacuolar-type H+-ATPase catalytic subunit A/Vma1 [Energy production and conversion]; Archaeal/vacuolar-type H+-ATPase catalytic subunit A/Vma1 is part of the Pathway/BioSystem: A/V-type ATP synthase


Pssm-ID: 440769 [Multi-domain]  Cd Length: 583  Bit Score: 919.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  15 ESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGI 94
Cdd:COG1155     1 MMTKGKIVKINGPLVTAEGMGGAKMYEVVYVGEERLIGEVIRIEGDKATIQVYEETSGLKPGEPVESTGEPLSVELGPGL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  95 MGAIFDGIQRPLSDISSQTqSIYIPRGVNVSALSRDIKWEFIPSKnlRVGSHITGGDIYGIVNENSLIKHKIMLPPRNRG 174
Cdd:COG1155    81 LGNIFDGIQRPLDKIAEKS-GDFIPRGVDVPALDREKKWDFTPTV--KVGDKVSAGDILGTVQETPLIEHKIMVPPGVSG 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 175 SVTYIAPPGNYDASDVVLELE-FEGVKEKFSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFG 253
Cdd:COG1155   158 TVKEIAPEGEYTVEDTIAVLEdEDGEEHELTMYQKWPVRRPRPYKEKLPPSEPLITGQRVIDTFFPIAKGGTAAIPGPFG 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 254 CGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTmevDGKV-ESIMKRTALVANTSNMPVAAREASIYTGIT 332
Cdd:COG1155   238 TGKTVTQHQLAKWSDADIVVYVGCGERGNEMTEVLEEFPELI---DPKTgRPLMERTVLIANTSNMPVAAREASIYTGIT 314
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 333 LSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPerEGSVSIVGAVSP 412
Cdd:COG1155   315 IAEYYRDMGYDVALMADSTSRWAEALREISGRLEEMPGEEGYPAYLASRLAEFYERAGRVKTLGGE--EGSVTIIGAVSP 392
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 413 PGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTE-FVPLRTKAKEILQEEEDLAE 491
Cdd:COG1155   393 PGGDFSEPVTQNTLRIVKVFWALDASLAYARHYPAINWLTSYSLYLDDLAEWYDENVDPdWSELRNEAMDLLQEEAELQE 472
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 492 IVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVEttaqsdNKITWSIIR 571
Cdd:COG1155   473 IVRLVGEDALPDEDRLTLEVARLIREGFLQQNAFDDVDTYCPLEKQYKMLKLILTFYDKAFEALE------KGVPLSEIK 546
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....
gi 1279489789 572 EHmgEILYKLSSMKFkDPVKDGEAKIKadyaQLLEDMQNAFRSL 615
Cdd:COG1155   547 EL--PLREKIARMKY-SPENELLEKFD----ELEKEIDEEIEEL 583
PRK04192 PRK04192
V-type ATP synthase subunit A; Provisional
19-616 0e+00

V-type ATP synthase subunit A; Provisional


Pssm-ID: 235248 [Multi-domain]  Cd Length: 586  Bit Score: 889.52  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  19 GYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAI 98
Cdd:PRK04192    5 GKIVRVSGPLVVAEGMGGARMYEVVRVGEEGLIGEIIRIEGDKATIQVYEETSGIKPGEPVEFTGEPLSVELGPGLLGSI 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  99 FDGIQRPLSDISSQTqSIYIPRGVNVSALSRDIKWEFIPSknLRVGSHITGGDIYGIVNENSLIKHKIMLPPRNRGSVTY 178
Cdd:PRK04192   85 FDGIQRPLDELAEKS-GDFLERGVYVPALDREKKWEFTPT--VKVGDKVEAGDILGTVQETPSIEHKIMVPPGVSGTVKE 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 179 IAPPGNYDASDVVLELE-FEGVKEKFSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKT 257
Cdd:PRK04192  162 IVSEGDYTVDDTIAVLEdEDGEGVELTMMQKWPVRRPRPYKEKLPPVEPLITGQRVIDTFFPVAKGGTAAIPGPFGSGKT 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 258 VISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKveSIMKRTALVANTSNMPVAAREASIYTGITLSEYF 337
Cdd:PRK04192  242 VTQHQLAKWADADIVIYVGCGERGNEMTEVLEEFPELIDPKTGR--PLMERTVLIANTSNMPVAAREASIYTGITIAEYY 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 338 RDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPerEGSVSIVGAVSPPGGDF 417
Cdd:PRK04192  320 RDMGYDVLLMADSTSRWAEALREISGRLEEMPGEEGYPAYLASRLAEFYERAGRVKTLGGE--EGSVTIIGAVSPPGGDF 397
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 418 SDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHF-TEFVPLRTKAKEILQEEEDLAEIVQLV 496
Cdd:PRK04192  398 SEPVTQNTLRIVKVFWALDAELADRRHFPAINWLTSYSLYLDQVAPWWEENVdPDWRELRDEAMDLLQREAELQEIVRLV 477
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 497 GKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVEttaqsdNKITWSIIREhmGE 576
Cdd:PRK04192  478 GPDALPEEDRLILEVARLIREDFLQQNAFDPVDTYCPPEKQYEMLKLILTFYDEAFKALE------KGVPVSEILE--LE 549
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|
gi 1279489789 577 ILYKLSSMKFkDPVKDGEAKIKAdyaqLLEDMQNAFRSLE 616
Cdd:PRK04192  550 VRDRIARLKY-IPENEYLEKIDE----IFEKLEEELEELI 584
V_A-ATPase_A cd01134
V/A-type ATP synthase catalytic subunit A; V/A-type ATP synthase catalytic subunit A. These ...
85-457 0e+00

V/A-type ATP synthase catalytic subunit A; V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. Vacuolar (V-type) ATPases play major roles in endomembrane and plasma membrane proton transport in eukaryotes. They are found in multiple intracellular membranes including vacuoles, endosomes, lysosomes, Golgi-derived vesicles, secretory vesicles, as well as the plasma membrane. Archaea have a protein which is similar in sequence to V-ATPases, but functions like an F-ATPase (called A-ATPase). A similar protein is also found in a few bacteria.


Pssm-ID: 410878 [Multi-domain]  Cd Length: 288  Bit Score: 623.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  85 PLSVELGPGIMGAIFDGIQRPLSDISsQTQSIYIPRGVnvsalsrdikwefipsknlrvgshitggdiygivnenslikh 164
Cdd:cd01134     1 PLSVELGPGLLGSIFDGIQRPLEVIA-ETGSIFIPRGV------------------------------------------ 37
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 165 kimlpprnrgsvtyiappgnydasdvvlelefegvkekfsMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGG 244
Cdd:cd01134    38 ----------------------------------------NVQRWPVRQPRPVKEKLPPNVPLLTGQRVLDTLFPVAKGG 77
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 245 TTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGkvESIMKRTALVANTSNMPVAARE 324
Cdd:cd01134    78 TAAIPGPFGCGKTVISQSLSKWSNSDVVIYVGCGERGNEMAEVLEEFPELKDPITG--ESLMERTVLIANTSNMPVAARE 155
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 325 ASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSV 404
Cdd:cd01134   156 ASIYTGITIAEYFRDMGYNVSLMADSTSRWAEALREISGRLEEMPAEEGYPAYLGARLAEFYERAGRVRCLGSPGREGSV 235
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1279489789 405 SIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKY 457
Cdd:cd01134   236 TIVGAVSPPGGDFSEPVTQATLRIVQVFWGLDKKLAQRRHFPSINWLISYSKY 288
ATP-synt_ab pfam00006
ATP synthase alpha/beta family, nucleotide-binding domain; This entry includes the ATP ...
230-455 7.98e-103

ATP synthase alpha/beta family, nucleotide-binding domain; This entry includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho.


Pssm-ID: 425417 [Multi-domain]  Cd Length: 212  Bit Score: 310.44  E-value: 7.98e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 230 GQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPEltmevdgkvESIMKRT 309
Cdd:pfam00006   1 GIRAIDGLLPIGRGQRIGIFGGSGVGKTVLAGMIARQASADVVVYALIGERGREVREFIEELLG---------SGALKRT 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 310 ALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERA 389
Cdd:pfam00006  72 VVVVATSDEPPLARYRAPYTALTIAEYFRDQGKDVLLIMDSLTRFAEALREISLALGEPPGREGYPPSVFSLLARLLERA 151
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1279489789 390 GRVKclgnpEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYS 455
Cdd:pfam00006 152 GRVK-----GKGGSITALPTVLVPGDDITDPIPDNTRSILDGQIVLSRDLAEKGHYPAIDVLASVS 212
 
Name Accession Description Interval E-value
V-ATPase_V1_A TIGR01042
V-type (H+)-ATPase V1, A subunit; This models eukaryotic vacuolar (H+)-ATPase that is ...
17-609 0e+00

V-type (H+)-ATPase V1, A subunit; This models eukaryotic vacuolar (H+)-ATPase that is responsible for acidifying cellular compartments. This enzyme shares extensive sequence similarity with archaeal ATP synthase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273411 [Multi-domain]  Cd Length: 591  Bit Score: 1258.50  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  17 TFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMG 96
Cdd:TIGR01042   1 EYGYIYKVSGPVVVAENMAGAAMYELVRVGHDELVGEIIRLEGDKATIQVYEETSGLTVGDPVLRTGKPLSVELGPGILG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  97 AIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDIKWEFIPsKNLRVGSHITGGDIYGIVNENSLIKHKIMLPPRNRGSV 176
Cdd:TIGR01042  81 NIFDGIQRPLKAIAEQSQSIYIPRGVNVPALDRDKKWEFTP-KKLRVGDHITGGDIYGTVFENSLIKHKIMLPPRARGTI 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 177 TYIAPPGNYDASDVVLELEFEGVKEKFSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGK 256
Cdd:TIGR01042 160 TYIAPAGNYTVDDTVLEVEFQGVKKKFSMLQTWPVRSPRPVTEKLPANTPLLTGQRVLDALFPCVQGGTTAIPGAFGCGK 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 257 TVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEY 336
Cdd:TIGR01042 240 TVISQSLSKYSNSDAIVYVGCGERGNEMAEVLMDFPELTMEVDGREESIMKRTTLVANTSNMPVAAREASIYTGITLAEY 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 337 FRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGD 416
Cdd:TIGR01042 320 FRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGSPEREGSVSIVGAVSPPGGD 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 417 FSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLV 496
Cdd:TIGR01042 400 FSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALEEFYEKFYPEFVPLRTKAKEILQEEEDLNEIVQLV 479
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 497 GKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVETTAQSDNKITWSIIREHMGE 576
Cdd:TIGR01042 480 GKDALAETDKITLEVAKLIKEDFLQQNGYTPYDRFCPFYKTVGMMRNMIAFYDLARQAVERTAQDDNKITWSIIKESLGD 559
                         570       580       590
                  ....*....|....*....|....*....|...
gi 1279489789 577 ILYKLSSMKFKDPVkDGEAKIKADYAQLLEDMQ 609
Cdd:TIGR01042 560 LLYRLSSMKFEDPS-DGEAKIKADYEKLNEDMQ 591
NtpA COG1155
Archaeal/vacuolar-type H+-ATPase catalytic subunit A/Vma1 [Energy production and conversion]; ...
15-615 0e+00

Archaeal/vacuolar-type H+-ATPase catalytic subunit A/Vma1 [Energy production and conversion]; Archaeal/vacuolar-type H+-ATPase catalytic subunit A/Vma1 is part of the Pathway/BioSystem: A/V-type ATP synthase


Pssm-ID: 440769 [Multi-domain]  Cd Length: 583  Bit Score: 919.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  15 ESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGI 94
Cdd:COG1155     1 MMTKGKIVKINGPLVTAEGMGGAKMYEVVYVGEERLIGEVIRIEGDKATIQVYEETSGLKPGEPVESTGEPLSVELGPGL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  95 MGAIFDGIQRPLSDISSQTqSIYIPRGVNVSALSRDIKWEFIPSKnlRVGSHITGGDIYGIVNENSLIKHKIMLPPRNRG 174
Cdd:COG1155    81 LGNIFDGIQRPLDKIAEKS-GDFIPRGVDVPALDREKKWDFTPTV--KVGDKVSAGDILGTVQETPLIEHKIMVPPGVSG 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 175 SVTYIAPPGNYDASDVVLELE-FEGVKEKFSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFG 253
Cdd:COG1155   158 TVKEIAPEGEYTVEDTIAVLEdEDGEEHELTMYQKWPVRRPRPYKEKLPPSEPLITGQRVIDTFFPIAKGGTAAIPGPFG 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 254 CGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTmevDGKV-ESIMKRTALVANTSNMPVAAREASIYTGIT 332
Cdd:COG1155   238 TGKTVTQHQLAKWSDADIVVYVGCGERGNEMTEVLEEFPELI---DPKTgRPLMERTVLIANTSNMPVAAREASIYTGIT 314
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 333 LSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPerEGSVSIVGAVSP 412
Cdd:COG1155   315 IAEYYRDMGYDVALMADSTSRWAEALREISGRLEEMPGEEGYPAYLASRLAEFYERAGRVKTLGGE--EGSVTIIGAVSP 392
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 413 PGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTE-FVPLRTKAKEILQEEEDLAE 491
Cdd:COG1155   393 PGGDFSEPVTQNTLRIVKVFWALDASLAYARHYPAINWLTSYSLYLDDLAEWYDENVDPdWSELRNEAMDLLQEEAELQE 472
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 492 IVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVEttaqsdNKITWSIIR 571
Cdd:COG1155   473 IVRLVGEDALPDEDRLTLEVARLIREGFLQQNAFDDVDTYCPLEKQYKMLKLILTFYDKAFEALE------KGVPLSEIK 546
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....
gi 1279489789 572 EHmgEILYKLSSMKFkDPVKDGEAKIKadyaQLLEDMQNAFRSL 615
Cdd:COG1155   547 EL--PLREKIARMKY-SPENELLEKFD----ELEKEIDEEIEEL 583
PRK04192 PRK04192
V-type ATP synthase subunit A; Provisional
19-616 0e+00

V-type ATP synthase subunit A; Provisional


Pssm-ID: 235248 [Multi-domain]  Cd Length: 586  Bit Score: 889.52  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  19 GYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAI 98
Cdd:PRK04192    5 GKIVRVSGPLVVAEGMGGARMYEVVRVGEEGLIGEIIRIEGDKATIQVYEETSGIKPGEPVEFTGEPLSVELGPGLLGSI 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  99 FDGIQRPLSDISSQTqSIYIPRGVNVSALSRDIKWEFIPSknLRVGSHITGGDIYGIVNENSLIKHKIMLPPRNRGSVTY 178
Cdd:PRK04192   85 FDGIQRPLDELAEKS-GDFLERGVYVPALDREKKWEFTPT--VKVGDKVEAGDILGTVQETPSIEHKIMVPPGVSGTVKE 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 179 IAPPGNYDASDVVLELE-FEGVKEKFSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKT 257
Cdd:PRK04192  162 IVSEGDYTVDDTIAVLEdEDGEGVELTMMQKWPVRRPRPYKEKLPPVEPLITGQRVIDTFFPVAKGGTAAIPGPFGSGKT 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 258 VISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKveSIMKRTALVANTSNMPVAAREASIYTGITLSEYF 337
Cdd:PRK04192  242 VTQHQLAKWADADIVIYVGCGERGNEMTEVLEEFPELIDPKTGR--PLMERTVLIANTSNMPVAAREASIYTGITIAEYY 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 338 RDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPerEGSVSIVGAVSPPGGDF 417
Cdd:PRK04192  320 RDMGYDVLLMADSTSRWAEALREISGRLEEMPGEEGYPAYLASRLAEFYERAGRVKTLGGE--EGSVTIIGAVSPPGGDF 397
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 418 SDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHF-TEFVPLRTKAKEILQEEEDLAEIVQLV 496
Cdd:PRK04192  398 SEPVTQNTLRIVKVFWALDAELADRRHFPAINWLTSYSLYLDQVAPWWEENVdPDWRELRDEAMDLLQREAELQEIVRLV 477
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 497 GKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVEttaqsdNKITWSIIREhmGE 576
Cdd:PRK04192  478 GPDALPEEDRLILEVARLIREDFLQQNAFDPVDTYCPPEKQYEMLKLILTFYDEAFKALE------KGVPVSEILE--LE 549
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|
gi 1279489789 577 ILYKLSSMKFkDPVKDGEAKIKAdyaqLLEDMQNAFRSLE 616
Cdd:PRK04192  550 VRDRIARLKY-IPENEYLEKIDE----IFEKLEEELEELI 584
ATP_syn_A_arch TIGR01043
ATP synthase archaeal, A subunit; Archaeal ATP synthase shares extensive sequence similarity ...
19-613 0e+00

ATP synthase archaeal, A subunit; Archaeal ATP synthase shares extensive sequence similarity with eukaryotic and prokaryotic V-type (H+)-ATPases. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 130115 [Multi-domain]  Cd Length: 578  Bit Score: 808.95  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  19 GYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAI 98
Cdd:TIGR01043   2 GRIIRVSGPLVVADGMKGAQMYEVVKVGEEGLIGEIIRIEGDKAFIQVYEETSGIKPGEPVVGTGAPLSVELGPGLLGSI 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  99 FDGIQRPLSDISSQTQSiYIPRGVNVSALSRDIKWEFIPSknLRVGSHITGGDIYGIVNENSLIKHKIMLPPRNRGSVTY 178
Cdd:TIGR01043  82 YDGVQRPLDVLKEKTGD-FIARGVDAPGLDRDKKWHFKPT--VKEGDKVEGGDIIGVVPETSLIEHKILVPPNVEGEIVE 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 179 IAPPGNYDASDVVLELEFEGvKEKFSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTV 258
Cdd:TIGR01043 159 IAEEGDYTVEDTIAVVDTDG-DEEIKMYQKWPVRIPRPYKEKLPPEVPLITGQRILDTFFPIAKGGTAAIPGPFGSGKTV 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 259 ISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKveSIMKRTALVANTSNMPVAAREASIYTGITLSEYFR 338
Cdd:TIGR01043 238 TQHQLAKWSDADIVVYIGCGERGNEMTDVLEEFPELKDPKTGK--PLMERTVLIANTSNMPVAAREASIYTGITIAEYFR 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 339 DMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFS 418
Cdd:TIGR01043 316 DMGYDVALMADSTSRWAEAMREISGRLEEMPGEEGYPAYLASRLAEFYERAGRVKTLGGEERVGSVTVIGAVSPPGGDFS 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 419 DPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFT-EFVPLRTKAKEILQEEEDLAEIVQLVG 497
Cdd:TIGR01043 396 EPVTQNTLRIVKVFWALDADLAQRRHFPAINWLQSYSLYVDLVQDWWHENVDpDWREMRDEAMDLLQKESELQEIVQLVG 475
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 498 KASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVETTAQSDnKITWSIIREhmgei 577
Cdd:TIGR01043 476 PDALPERQKLILEVARMIREAFLQQNAFDPVDTYCPPQKQYRILRAIMNFYDEAMEALERGVPVE-EILKLEVKE----- 549
                         570       580       590
                  ....*....|....*....|....*....|....*.
gi 1279489789 578 lyKLSSMKFKDPVkdgeaKIKADYAQLLEDMQNAFR 613
Cdd:TIGR01043 550 --EIGRMKYEPDN-----DILAKIDEILEKIEKEFK 578
V_A-ATPase_A cd01134
V/A-type ATP synthase catalytic subunit A; V/A-type ATP synthase catalytic subunit A. These ...
85-457 0e+00

V/A-type ATP synthase catalytic subunit A; V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. Vacuolar (V-type) ATPases play major roles in endomembrane and plasma membrane proton transport in eukaryotes. They are found in multiple intracellular membranes including vacuoles, endosomes, lysosomes, Golgi-derived vesicles, secretory vesicles, as well as the plasma membrane. Archaea have a protein which is similar in sequence to V-ATPases, but functions like an F-ATPase (called A-ATPase). A similar protein is also found in a few bacteria.


Pssm-ID: 410878 [Multi-domain]  Cd Length: 288  Bit Score: 623.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  85 PLSVELGPGIMGAIFDGIQRPLSDISsQTQSIYIPRGVnvsalsrdikwefipsknlrvgshitggdiygivnenslikh 164
Cdd:cd01134     1 PLSVELGPGLLGSIFDGIQRPLEVIA-ETGSIFIPRGV------------------------------------------ 37
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 165 kimlpprnrgsvtyiappgnydasdvvlelefegvkekfsMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGG 244
Cdd:cd01134    38 ----------------------------------------NVQRWPVRQPRPVKEKLPPNVPLLTGQRVLDTLFPVAKGG 77
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 245 TTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGkvESIMKRTALVANTSNMPVAARE 324
Cdd:cd01134    78 TAAIPGPFGCGKTVISQSLSKWSNSDVVIYVGCGERGNEMAEVLEEFPELKDPITG--ESLMERTVLIANTSNMPVAARE 155
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 325 ASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSV 404
Cdd:cd01134   156 ASIYTGITIAEYFRDMGYNVSLMADSTSRWAEALREISGRLEEMPAEEGYPAYLGARLAEFYERAGRVRCLGSPGREGSV 235
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1279489789 405 SIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKY 457
Cdd:cd01134   236 TIVGAVSPPGGDFSEPVTQATLRIVQVFWGLDKKLAQRRHFPSINWLISYSKY 288
PRK14698 PRK14698
V-type ATP synthase subunit A; Provisional
257-606 4.07e-118

V-type ATP synthase subunit A; Provisional


Pssm-ID: 184795 [Multi-domain]  Cd Length: 1017  Bit Score: 375.51  E-value: 4.07e-118
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  257 TVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKveSIMKRTALVANTSNMPVAAREASIYTGITLSEY 336
Cdd:PRK14698   670 TVTQHQLAKWSDAQVVIYIGCGERGNEMTDVLEEFPKLKDPKTGK--PLMERTVLIANTSNMPVAAREASIYTGITIAEY 747
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  337 FRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGD 416
Cdd:PRK14698   748 FRDMGYDVALMADSTSRWAEALREISGRLEEMPGEEGYPAYLASKLAEFYERAGRVVTLGSDYRVGSVSVIGAVSPPGGD 827
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  417 FSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFT-EFVPLRTKAKEILQEEEDLAEIVQL 495
Cdd:PRK14698   828 FSEPVVQNTLRVVKVFWALDADLARRRHFPAINWLTSYSLYVDAVKDWWHKNVDpEWKAMRDKAMELLQKEAELQEIVRI 907
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  496 VGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMARRAVETTAQSDnKITWSIIREHMG 575
Cdd:PRK14698   908 VGPDALPERERAILLVARMLREDYLQQDAFDEVDTYCPPEKQVTMMRVLLNFYDKTMDAISRGVPLE-EIAKLPVREEIG 986
                          330       340       350
                   ....*....|....*....|....*....|.
gi 1279489789  576 EilyklssMKFKDPVKDGEAKIKADYAQLLE 606
Cdd:PRK14698   987 R-------MKFEPDIEKIKALIDKTNEQFDE 1010
ATP-synt_ab pfam00006
ATP synthase alpha/beta family, nucleotide-binding domain; This entry includes the ATP ...
230-455 7.98e-103

ATP synthase alpha/beta family, nucleotide-binding domain; This entry includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho.


Pssm-ID: 425417 [Multi-domain]  Cd Length: 212  Bit Score: 310.44  E-value: 7.98e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 230 GQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPEltmevdgkvESIMKRT 309
Cdd:pfam00006   1 GIRAIDGLLPIGRGQRIGIFGGSGVGKTVLAGMIARQASADVVVYALIGERGREVREFIEELLG---------SGALKRT 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 310 ALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERA 389
Cdd:pfam00006  72 VVVVATSDEPPLARYRAPYTALTIAEYFRDQGKDVLLIMDSLTRFAEALREISLALGEPPGREGYPPSVFSLLARLLERA 151
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1279489789 390 GRVKclgnpEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYS 455
Cdd:pfam00006 152 GRVK-----GKGGSITALPTVLVPGDDITDPIPDNTRSILDGQIVLSRDLAEKGHYPAIDVLASVS 212
RecA-like_ion-translocating_ATPases cd19476
RecA-like domain of ion-translocating ATPases; RecA-like NTPases. This family includes the ...
205-457 1.11e-90

RecA-like domain of ion-translocating ATPases; RecA-like NTPases. This family includes the NTP-binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410884 [Multi-domain]  Cd Length: 270  Bit Score: 281.27  E-value: 1.11e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 205 MVQVWPVRQVRP-VTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNS---DVIIYVGCGER 280
Cdd:cd19476    28 TKQRRPIHLKAPnPIERLPPEEPLQTGIKVIDLLAPYGRGQKIGIFGGSGVGKTVLAMQLARNQAKahaGVVVFAGIGER 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 281 GNEMSEVLRDFPELtmevdgkveSIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALRE 360
Cdd:cd19476   108 GREVNDLYEEFTKS---------GAMERTVVVANTANDPPGARMRVPYTGLTIAEYFRDNGQHVLLIIDDISRYAEALRE 178
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 361 ISGRLAEMPADSGYPAYLGARLASFYERAGRVKclgnpEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLA 440
Cdd:cd19476   179 MSALLGEPPGREGYPPYLFTKLATLYERAGKVK-----DGGGSITAIPAVSTPGDDLTDPIPDNTFAILDGQIVLSRELA 253
                         250
                  ....*....|....*..
gi 1279489789 441 QRKHFPSVNWLISYSKY 457
Cdd:cd19476   254 RKGIYPAINVLDSTSRV 270
PRK14698 PRK14698
V-type ATP synthase subunit A; Provisional
19-263 5.01e-73

V-type ATP synthase subunit A; Provisional


Pssm-ID: 184795 [Multi-domain]  Cd Length: 1017  Bit Score: 253.41  E-value: 5.01e-73
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789   19 GYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAI 98
Cdd:PRK14698     5 GRIIRVTGPLVIADGMKGAKMYEVVRVGELGLIGEIIRLEGDKAVIQVYEETAGLKPGEPVEGTGSSLSVELGPGLLTSI 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789   99 FDGIQRPLSDISSQTQSiYIPRGVNVSALSRDIKWEFIPskNLRVGSHITGGDIYGIVNENSLIKHKIMLPPRNRGSVTY 178
Cdd:PRK14698    85 YDGIQRPLEVIREKSGD-FIARGISAPALPRDKKWHFIP--KVKVGDKVVGGDIIGEVPETSIITHKIMVPPGIEGEIVE 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  179 IAPPGNYDASDVVLELEF-EGVKEKFSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKT 257
Cdd:PRK14698   162 IADEGEYTIEEVIAKVKTpSGEIKELKMYQRWPVRVKRPYKEKLPPEVPLITGQRVIDTFFPQAKGGTAAIPGPFGSGKC 241

                   ....*.
gi 1279489789  258 VISQSL 263
Cdd:PRK14698   242 VDGDTL 247
ATP-synt_ab_Xtn pfam16886
ATPsynthase alpha/beta subunit N-term extension; ATP-synt_ab_Xtn is an extension of the ...
99-221 3.38e-64

ATPsynthase alpha/beta subunit N-term extension; ATP-synt_ab_Xtn is an extension of the alpha-beta catalytic subunit of VATA or V-type proton ATPase catalytic subunit at the N-terminal end. It is found from bacteria to humans, and was not modelled in family ATP-synt_ab, pfam00006.


Pssm-ID: 465299 [Multi-domain]  Cd Length: 120  Bit Score: 206.87  E-value: 3.38e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  99 FDGIQRPLSDISSQTQSiYIPRGVNVSALSRDIKWEFIPskNLRVGSHITGGDIYGIVNENSLIKHKIMLPPRNRGSVTY 178
Cdd:pfam16886   1 FDGIQRPLEKIAEKSGS-FIPRGVDVPALDREKKWEFTP--TVKVGDKVSGGDILGTVQETSLIEHKIMVPPGVSGTVTE 77
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1279489789 179 IAPPGNYDASDVVLELEFEGVKEKFSMVQVWPVRQVRPVTEKL 221
Cdd:pfam16886  78 IAPEGEYTVEDTIAEVEDEGKEKELTMMQKWPVRRPRPYKEKL 120
ATP-synt_V_A-type_alpha_C cd18111
V/A-type ATP synthase catalytic subunit A (alpha), C-terminal domain; The alpha (A) subunit of ...
472-577 8.50e-51

V/A-type ATP synthase catalytic subunit A (alpha), C-terminal domain; The alpha (A) subunit of the V1/A1 complex of V/A-type ATP synthases, C-terminal domain. The V- and A-type family of ATPases are composed of two linked multi-subunit complexes: the V1 and A1 complexes contain three copies each of the alpha and beta subunits that form the soluble catalytic core, which is involved in ATP synthesis/hydrolysis, and the Vo or Ao complex that forms the membrane-embedded proton pore. The A-ATP synthase (AoA1-ATPase) is found in archaea and functions like F-ATP synthase. Structurally, however, the A-ATP synthase is more closely related to the V-ATP synthase (vacuolar VoV1-ATPase), which is a proton-translocating ATPase responsible for acidification of eukaryotic intracellular compartments and for ATP synthesis in archaea and some eubacteria. Collectively, the V- and A-type synthases can function in both ATP synthesis and hydrolysis modes.


Pssm-ID: 349746 [Multi-domain]  Cd Length: 105  Bit Score: 170.65  E-value: 8.50e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 472 FVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMISFYDMA 551
Cdd:cd18111     1 WVELRTEAMEILQEEAELQEIVQLVGPDALPEEDRLTLEVARMIREDFLQQNAFDEVDTYCPLEKQYKMLKLILTFYDKA 80
                          90       100
                  ....*....|....*....|....*.
gi 1279489789 552 RRAVEtTAQSDNKITWSIIREHMGEI 577
Cdd:cd18111    81 LEALE-KGVPLSKILELPVREKIARM 105
fliI_yscN TIGR01026
ATPase, FliI/YscN family; This family of ATPases demonstrates extensive homology with ATP ...
44-522 1.03e-45

ATPase, FliI/YscN family; This family of ATPases demonstrates extensive homology with ATP synthase F1, beta subunit. It is a mixture of members with two different protein functions. The first group is exemplified by Salmonella typhimurium FliI protein. It is needed for flagellar assembly, its ATPase activity is required for flagellation, and it may be involved in a specialized protein export pathway that proceeds without signal peptide cleavage. The second group of proteins function in the export of virulence proteins; exemplified by Yersinia sp. YscN protein an ATPase involved in the type III secretory pathway for the antihost Yops proteins. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273401 [Multi-domain]  Cd Length: 440  Bit Score: 167.55  E-value: 1.03e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  44 RVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSdissqtqsiyiprgvn 123
Cdd:TIGR01026  53 RGSEGRLVAEVVGFNGEFVFLMPYEEVEGVRPGSKVLATGEGLSIKVGDGLLGRVLDGLGKPID---------------- 116
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 124 vsalsrdikwefipsknlrvgshiTGGDIYGIVNENSLIKHKImlPPRNRGsvtyiappgnydasdvvlelefegvkekf 203
Cdd:TIGR01026 117 ------------------------GKGKFLDNVETEGLITAPI--NPLKRA----------------------------- 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 204 smvqvwPVRQVrpvteklpanhpLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNE 283
Cdd:TIGR01026 142 ------PIREI------------LSTGVRSIDGLLTVGKGQRIGIFAGSGVGKSTLLGMIARNTEADVNVIALIGERGRE 203
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 284 msevLRDFPELTMEVDGkvesiMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISG 363
Cdd:TIGR01026 204 ----VREFIEHDLGEEG-----LKRSVVVVATSDQSPLLRLKGAYVATAIAEYFRDQGKDVLLLMDSVTRFAMAQREIGL 274
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 364 RLAEMPADSGYPAYLGARLASFYERAGrvkclgnPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRK 443
Cdd:TIGR01026 275 AAGEPPATKGYTPSVFSTLPRLLERAG-------ASGKGSITAFYTVLVEGDDMNEPIADSVRGILDGHIVLSRALAQRG 347
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 444 HFPSVNWLISYSKYMRAL--DEYYDKhftefvplRTKAKEIL---QEEEDLAEIvQLVGKASLAETDKITLEVAKLIKdd 518
Cdd:TIGR01026 348 HYPAIDVLASISRLMTAIvsEEHRRA--------ARKFRELLskyKDNEDLIRI-GAYQRGSDRELDFAIAKYPKLER-- 416

                  ....
gi 1279489789 519 FLQQ 522
Cdd:TIGR01026 417 FLKQ 420
PRK06820 PRK06820
EscN/YscN/HrcN family type III secretion system ATPase;
18-546 2.03e-41

EscN/YscN/HrcN family type III secretion system ATPase;


Pssm-ID: 180712 [Multi-domain]  Cd Length: 440  Bit Score: 155.74  E-value: 2.03e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  18 FGYVHGVsGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGA 97
Cdd:PRK06820   30 RGPIVEI-GPTLLRASLPGVAQGELCRIEPQGMLAEVVSIEQEMALLSPFASSDGLRCGQWVTPLGHMHQVQVGADLAGR 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  98 IFDGIQRPLSDissqtqsiYIPRGVNVSALsrdikwefipsknlrvgshitggdiygivnenslikhkimlpprnrgsvt 177
Cdd:PRK06820  109 ILDGLGAPIDG--------GPPLTGQWREL-------------------------------------------------- 130
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 178 YIAPPGnydasdvvlelefegvkekfsmvqvwpvrqvrPVTEKlPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKT 257
Cdd:PRK06820  131 DCPPPS--------------------------------PLTRQ-PIEQMLTTGIRAIDGILSCGEGQRIGIFAAAGVGKS 177
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 258 VISQSLSKYSNSDVIIYVGCGERGNEmsevLRDFPELTMEVDGKvesimKRTALVANTSNMPVAAREASIYTGITLSEYF 337
Cdd:PRK06820  178 TLLGMLCADSAADVMVLALIGERGRE----VREFLEQVLTPEAR-----ARTVVVVATSDRPALERLKGLSTATTIAEYF 248
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 338 RDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGrvkclgnPEREGSVSIVGAVSPPGGDF 417
Cdd:PRK06820  249 RDRGKKVLLMADSLTRYARAAREIGLAAGEPPAAGSFPPSVFANLPRLLERTG-------NSDRGSITAFYTVLVEGDDM 321
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 418 SDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEyydkhfTEFVPLRTKAKEILQEEEDLAEIVQlVG 497
Cdd:PRK06820  322 NEPVADEVRSLLDGHIVLSRRLAGAGHYPAIDIAASVSRIMPQIVS------AGQLAMAQKLRRMLACYQEIELLVR-VG 394
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1279489789 498 ---KASLAETDKiTLEVAKLIKdDFLQQNGytpyDRFCPFYKTVGMLSNMIS 546
Cdd:PRK06820  395 eyqAGEDLQADE-ALQRYPAIC-AFLQQDH----SETAHLETTLEHLAQVVG 440
FliI COG1157
Flagellar biosynthesis/type III secretory pathway ATPase FliI [Cell motility, Intracellular ...
8-545 3.77e-40

Flagellar biosynthesis/type III secretory pathway ATPase FliI [Cell motility, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440771 [Multi-domain]  Cd Length: 433  Bit Score: 152.11  E-value: 3.77e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789   8 KIRDEDKESTFGYVHGVSGPVVTAcdmAG--AAMYELVRV---GHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRT 82
Cdd:COG1157    10 RLEELPPVRVSGRVTRVVGLLIEA---VGpdASIGELCEIetaDGRPVLAEVVGFRGDRVLLMPLGDLEGISPGARVVPT 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  83 GKPLSVELGPGIMGAIFDGIQRPLSDissqtqsiyipRGvnvsalsrdikwefipsknlrvgshitggdiygivnensli 162
Cdd:COG1157    87 GRPLSVPVGDGLLGRVLDGLGRPLDG-----------KG----------------------------------------- 114
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 163 khkimlPPRNRGSVTYIAPPGNYdasdvvleLEfegvkekfsmvqvwpvRQvrPVTEklpanhPLLTGQRVLDALFPCVQ 242
Cdd:COG1157   115 ------PLPGEERRPLDAPPPNP--------LE----------------RA--RITE------PLDTGVRAIDGLLTVGR 156
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 243 G---GTTAipGAfGCGKTVISQSLSKYSNSDVIIyVG-CGERGNEmsevLRDFPELTMEVDGkvesiMKRTALVANTSNM 318
Cdd:COG1157   157 GqriGIFA--GS-GVGKSTLLGMIARNTEADVNV-IAlIGERGRE----VREFIEDDLGEEG-----LARSVVVVATSDE 223
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 319 PVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISgrLA--EMPADSGYPAYLGARLASFYERAGrvkclg 396
Cdd:COG1157   224 PPLMRLRAAYTATAIAEYFRDQGKNVLLLMDSLTRFAMAQREIG--LAagEPPATRGYPPSVFALLPRLLERAG------ 295
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 397 nPEREGSVSIVGAVSPPGGDFSDPVTSATLGI-----VqvfwgLDKKLAQRKHFPSVNWLISYSKYMRAL--DEYYDkhf 469
Cdd:COG1157   296 -NGGKGSITAFYTVLVEGDDMNDPIADAVRGIldghiV-----LSRKLAERGHYPAIDVLASISRVMPDIvsPEHRA--- 366
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 470 tefvpLRTKAKEIL---QEEEDLaeIvqLVG---KASLAETDK-ITLeVAKLikDDFLQQngytPYDRFCPFYKTVGMLS 542
Cdd:COG1157   367 -----LARRLRRLLaryEENEDL--I--RIGayqPGSDPELDEaIAL-IPAI--EAFLRQ----GMDERVSFEESLAQLA 430

                  ...
gi 1279489789 543 NMI 545
Cdd:COG1157   431 ELL 433
ATP-synt_V_A-type_alpha_N cd18119
V/A-type ATP synthase catalytic subunit A (alpha), N-terminal domain; The alpha (A) subunit of ...
18-84 4.09e-39

V/A-type ATP synthase catalytic subunit A (alpha), N-terminal domain; The alpha (A) subunit of the V1/A1 complexes of V/A-type ATP synthases, N-terminal domain. The V- and A-type family of ATPases are composed of two linked multi-subunit complexes: the V1 or A1 complex contain three copies each of the alpha and beta subunits that form the soluble catalytic core, which is involved in ATP synthesis/hydrolysis, and the Vo or Ao complex that forms the membrane-embedded proton pore. The A-ATP synthase (AoA1-ATPase) is found in archaea and functions like F-ATP synthase. Structurally, however, the A-ATP synthase is more closely related to the V-ATP synthase (vacuolar VoV1-ATPase), which is a proton-translocating ATPase responsible for acidification of eukaryotic intracellular compartments and for ATP synthesis in archaea and some eubacteria. Collectively, the V- and A-type synthases can function in both ATP synthesis and hydrolysis modes.


Pssm-ID: 349743 [Multi-domain]  Cd Length: 67  Bit Score: 137.66  E-value: 4.09e-39
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1279489789  18 FGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGK 84
Cdd:cd18119     1 KGKIYRVSGPVVVAEGMSGAAMYELVRVGEEGLIGEIIRLEGDKATIQVYEETSGLKVGEPVERTGK 67
ATPase_flagellum-secretory_path_III cd01136
Flagellum-specific ATPase/type III secretory pathway virulence-related protein; ...
222-456 9.48e-39

Flagellum-specific ATPase/type III secretory pathway virulence-related protein; Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they both are proton-driven rotary molecular devices. However, the main function of the bacterial flagellar motor is to rotate the flagellar filament for cell motility. Intracellular pathogens such as Salmonella and Chlamydia also have proteins which are similar to the flagellar-specific ATPase, but function in the secretion of virulence-related proteins via the type III secretory pathway.


Pssm-ID: 410880 [Multi-domain]  Cd Length: 265  Bit Score: 143.47  E-value: 9.48e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 222 PANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEmsevLRDFPELTMEVDGk 301
Cdd:cd01136    46 PIEQPLPTGVRAIDGLLTCGEGQRIGIFAGSGVGKSTLLGMIARNTDADVNVIALIGERGRE----VREFIEKDLGEEG- 120
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 302 vesiMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGAR 381
Cdd:cd01136   121 ----LKRSVLVVATSDESPLLRVRAAYTATAIAEYFRDQGKKVLLLMDSLTRFAMAQREVGLAAGEPPTRRGYPPSVFAL 196
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1279489789 382 LASFYERAGrvkclgnPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSK 456
Cdd:cd01136   197 LPRLLERAG-------NGEKGSITAFYTVLVEGDDFNDPIADEVRSILDGHIVLSRRLAERGHYPAIDVLASISR 264
FliI_clade1 TIGR03496
flagellar protein export ATPase FliI; Members of this protein family are the FliI protein of ...
19-523 1.10e-34

flagellar protein export ATPase FliI; Members of this protein family are the FliI protein of bacterial flagellum systems. This protein acts to drive protein export for flagellar biosynthesis. The most closely related family is the YscN family of bacterial type III secretion systems. This model represents one (of three) segment of the FliI family tree. These have been modeled separately in order to exclude the type III secretion ATPases more effectively. [Cellular processes, Chemotaxis and motility]


Pssm-ID: 274607 [Multi-domain]  Cd Length: 411  Bit Score: 136.07  E-value: 1.10e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  19 GYVHGVSGPVVTA--CDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMG 96
Cdd:TIGR03496   1 GRVTRVVGLVLEAvgLRAPVGSRCEIESSDGDPIEAEVVGFRGDRVLLMPLEDVEGLRPGARVFPLGGPLRLPVGDSLLG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  97 AIFDGIQRPLSDISsqtqsiyiprgvnvsalsrdikwefipsknlrvgshitggdiygivnenslikhkimlPPRNRGSV 176
Cdd:TIGR03496  81 RVIDGLGRPLDGKG----------------------------------------------------------PLDAGERV 102
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 177 TYIAPPGNydasdvvlelefegvkekfsmvqvwPVRQvRPVTEklpanhPLLTGQRVLDALFPCVQGGTTAIPGAFGCGK 256
Cdd:TIGR03496 103 PLYAPPIN-------------------------PLKR-APIDE------PLDVGVRAINGLLTVGRGQRMGIFAGSGVGK 150
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 257 TVISQSLSKYSNSDVIIyVG-CGERGNEmsevLRDFPELTMEVDGkvesiMKRTALVANTSNMPVAAREASIYTGITLSE 335
Cdd:TIGR03496 151 STLLGMMARYTEADVVV-VGlIGERGRE----VKEFIEDILGEEG-----LARSVVVAATADESPLMRLRAAFYATAIAE 220
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 336 YFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGrvkclgnPEREGSVSIVG--AVSPP 413
Cdd:TIGR03496 221 YFRDQGKDVLLLMDSLTRFAMAQREIALAIGEPPATKGYPPSVFAKLPQLVERAG-------NGEEGKGSITAfyTVLVE 293
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 414 GGDFSDPVTSATLGIVQvfwG---LDKKLAQRKHFPSVNWLISYSKYMRAL--DEYYDkhftefvpLRTKAKEIL---QE 485
Cdd:TIGR03496 294 GDDQQDPIADAARAILD---GhivLSRELAEQGHYPAIDILASISRVMPDVvsPEHRQ--------AARRFKQLLsryQE 362
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|
gi 1279489789 486 EEDLAEIvqlvGkASLAETDKITLEVAKLIK--DDFLQQN 523
Cdd:TIGR03496 363 NRDLISI----G-AYQAGSDPELDQAIALYPriEAFLQQG 397
PRK06936 PRK06936
EscN/YscN/HrcN family type III secretion system ATPase;
216-461 3.06e-33

EscN/YscN/HrcN family type III secretion system ATPase;


Pssm-ID: 180762 [Multi-domain]  Cd Length: 439  Bit Score: 132.57  E-value: 3.06e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 216 PVTEKLpANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEmsevLRDFPELT 295
Cdd:PRK06936  136 PMSRRL-IETPLSLGVRVIDGLLTCGEGQRMGIFAAAGGGKSTLLASLIRSAEVDVTVLALIGERGRE----VREFIESD 210
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 296 MEVDGkvesiMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYP 375
Cdd:PRK06936  211 LGEEG-----LRKAVLVVATSDRPSMERAKAGFVATSIAEYFRDQGKRVLLLMDSVTRFARAQREIGLAAGEPPTRRGYP 285
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 376 AYLGARLASFYERAGrvkclgnPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYS 455
Cdd:PRK06936  286 PSVFAALPRLMERAG-------QSDKGSITALYTVLVEGDDMTEPVADETRSILDGHIILSRKLAAANHYPAIDVLRSAS 358

                  ....*.
gi 1279489789 456 KYMRAL 461
Cdd:PRK06936  359 RVMNQI 364
PRK07594 PRK07594
EscN/YscN/HrcN family type III secretion system ATPase;
7-461 1.74e-32

EscN/YscN/HrcN family type III secretion system ATPase;


Pssm-ID: 136438 [Multi-domain]  Cd Length: 433  Bit Score: 130.07  E-value: 1.74e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789   7 PKIRDEDKESTFGYVHGVSGPVVTACdMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPL 86
Cdd:PRK07594   11 LKYPPPDGYCRWGRIQDVSATLLNAW-LPGVFMGELCCIKPGEELAEVVGINGSKALLSPFTSTIGLHCGQQVMALRRRH 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  87 SVELGPGIMGAIFDGIQRPLSDISsqtqsiyIPrgvnvsalsrDIKWEfipsknlrvgshitggdiygivnenslikhki 166
Cdd:PRK07594   90 QVPVGEALLGRVIDGFGRPLDGRE-------LP----------DVCWK-------------------------------- 120
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 167 mlpprnrgsvTYIAPPgnydasdvvlelefegvkekfsmvqvwPvrqvrPVTEKLPANHPLLTGQRVLDALFPCVQGGTT 246
Cdd:PRK07594  121 ----------DYDAMP---------------------------P-----PAMVRQPITQPLMTGIRAIDSVATCGEGQRV 158
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 247 AIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEmsevLRDFPELTMEVDGKvesimKRTALVANTSNMPVAAREAS 326
Cdd:PRK07594  159 GIFSAPGVGKSTLLAMLCNAPDADSNVLVLIGERGRE----VREFIDFTLSEETR-----KRCVIVVATSDRPALERVRA 229
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 327 IYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGrvkcLGNperEGSVSI 406
Cdd:PRK07594  230 LFVATTIAEFFRDNGKRVVLLADSLTRYARAAREIALAAGETAVSGEYPPGVFSALPRLLERTG----MGE---KGSITA 302
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1279489789 407 VGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRAL 461
Cdd:PRK07594  303 FYTVLVEGDDMNEPLADEVRSLLDGHIVLSRRLAERGHYPAIDVLATLSRVFPVV 357
fliI PRK07721
flagellar protein export ATPase FliI;
219-492 2.52e-32

flagellar protein export ATPase FliI;


Pssm-ID: 181092 [Multi-domain]  Cd Length: 438  Bit Score: 129.84  E-value: 2.52e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 219 EKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEmsevLRDFPELTMEV 298
Cdd:PRK07721  134 KRPPIREPMEVGVRAIDSLLTVGKGQRVGIFAGSGVGKSTLMGMIARNTSADLNVIALIGERGRE----VREFIERDLGP 209
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 299 DGkvesiMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYL 378
Cdd:PRK07721  210 EG-----LKRSIVVVATSDQPALMRIKGAYTATAIAEYFRDQGLNVMLMMDSVTRVAMAQREIGLAVGEPPTTKGYTPSV 284
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 379 GARLASFYERAGrvkclgnPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYM 458
Cdd:PRK07721  285 FAILPKLLERTG-------TNASGSITAFYTVLVDGDDMNEPIADTVRGILDGHFVLDRQLANKGQYPAINVLKSVSRVM 357
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1279489789 459 RALDEYYDKHFTEfvplrtKAKEIL---QEEEDLAEI 492
Cdd:PRK07721  358 NHIVSPEHKEAAN------RFRELLstyQNSEDLINI 388
PRK08149 PRK08149
FliI/YscN family ATPase;
215-522 1.88e-31

FliI/YscN family ATPase;


Pssm-ID: 236166 [Multi-domain]  Cd Length: 428  Bit Score: 127.03  E-value: 1.88e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 215 RPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEvlrdFPEl 294
Cdd:PRK08149  123 PSYAERRPIREPLITGVRAIDGLLTCGVGQRMGIFASAGCGKTSLMNMLIEHSEADVFVIGLIGERGREVTE----FVE- 197
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 295 TMEVDGKVEsimkRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGY 374
Cdd:PRK08149  198 SLRASSRRE----KCVLVYATSDFSSVDRCNAALVATTVAEYFRDQGKRVVLFIDSMTRYARALRDVALAAGELPARRGY 273
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 375 PAYLGARLASFYERAGRVKclgnperEGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISY 454
Cdd:PRK08149  274 PASVFDSLPRLLERPGATL-------AGSITAFYTVLLESEEEPDPIGDEIRSILDGHIYLSRKLAAKGHYPAIDVLKSV 346
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1279489789 455 SkymRALDEYYDKHFTEfvpLRTKAKEILQEEEDLAEIVQLvGKASL---AETDKITLEVAKLikDDFLQQ 522
Cdd:PRK08149  347 S---RVFGQVTDPKHRQ---LAAAFRKLLTRLEELQLFIDL-GEYRRgenADNDRAMDKRPAL--EAFLKQ 408
fliI PRK08927
flagellar protein export ATPase FliI;
226-523 2.97e-31

flagellar protein export ATPase FliI;


Pssm-ID: 236351 [Multi-domain]  Cd Length: 442  Bit Score: 126.63  E-value: 2.97e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 226 PLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDfpelTMEVDGkvesi 305
Cdd:PRK08927  141 PLDLGVRALNTFLTCCRGQRMGIFAGSGVGKSVLLSMLARNADADVSVIGLIGERGREVQEFLQD----DLGPEG----- 211
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 306 MKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASF 385
Cdd:PRK08927  212 LARSVVVVATSDEPALMRRQAAYLTLAIAEYFRDQGKDVLCLMDSVTRFAMAQREIGLSAGEPPTTKGYTPTVFAELPRL 291
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 386 YERAGRvkclgNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYM-RALDEy 464
Cdd:PRK08927  292 LERAGP-----GPIGEGTITGLFTVLVDGDDHNEPVADAVRGILDGHIVMERAIAERGRYPAINVLKSVSRTMpGCNDP- 365
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1279489789 465 ydkhftEFVPLRTKAKEILQEEEDLAEIVQLvgKASLAETDKITLEVAKLIKD--DFLQQN 523
Cdd:PRK08927  366 ------EENPLVRRARQLMATYADMEELIRL--GAYRAGSDPEVDEAIRLNPAleAFLRQG 418
PRK04196 PRK04196
V-type ATP synthase subunit B; Provisional
21-526 3.57e-28

V-type ATP synthase subunit B; Provisional


Pssm-ID: 235251 [Multi-domain]  Cd Length: 460  Bit Score: 118.00  E-value: 3.57e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  21 VHGVSGPVVTACDMAGAAMYELVRV---GHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLR-TGKPLSVELGPGIMG 96
Cdd:PRK04196    7 VSEIKGPLLFVEGVEGVAYGEIVEIelpNGEKRRGQVLEVSEDKAVVQVFEGTTGLDLKDTKVRfTGEPLKLPVSEDMLG 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  97 AIFDGIQRPLSD----ISSQTQSIyiprgvNVSAL---SRDIKWEFIPsknlrvgshiTGgdIYGIVNENSLIK-HKimL 168
Cdd:PRK04196   87 RIFDGLGRPIDGgpeiIPEKRLDI------NGAPInpvAREYPEEFIQ----------TG--ISAIDGLNTLVRgQK--L 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 169 P-------PRNRgsvtyIAppgnydasdvvlelefegvkekfsmVQVwpVRQVRpvteklpanhplltgqrvldalfpcV 241
Cdd:PRK04196  147 PifsgsglPHNE-----LA-------------------------AQI--ARQAK-------------------------V 169
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 242 QGGTTAipgaFgcgktvisqslskysnsdVIIYVGCGERGNEMSEVLRDFPEltmevdgkvESIMKRTALVANTSNMPVA 321
Cdd:PRK04196  170 LGEEEN----F------------------AVVFAAMGITFEEANFFMEDFEE---------TGALERSVVFLNLADDPAI 218
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 322 AREASIYTGITLSEYFR-DMGYHV-SMMADSTSrWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKclgnpE 399
Cdd:PRK04196  219 ERILTPRMALTAAEYLAfEKGMHVlVILTDMTN-YCEALREISAAREEVPGRRGYPGYMYTDLATIYERAGRIK-----G 292
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 400 REGSVSIVGAVSPPGGDFSDPVTSATLGIV--QVFwgLDKKLAQRKHFPSVNWLISYSKYMralDEYYDKHFTefvplRT 477
Cdd:PRK04196  293 KKGSITQIPILTMPDDDITHPIPDLTGYITegQIV--LSRELHRKGIYPPIDVLPSLSRLM---KDGIGEGKT-----RE 362
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1279489789 478 KAKEILQ-------EEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYT 526
Cdd:PRK04196  363 DHKDVANqlyaayaRGKDLRELAAIVGEEALSERDRKYLKFADAFEREFVNQGFDE 418
NtpB COG1156
Archaeal/vacuolar-type H+-ATPase subunit B/Vma2 [Energy production and conversion]; Archaeal ...
21-526 4.91e-28

Archaeal/vacuolar-type H+-ATPase subunit B/Vma2 [Energy production and conversion]; Archaeal/vacuolar-type H+-ATPase subunit B/Vma2 is part of the Pathway/BioSystem: A/V-type ATP synthase


Pssm-ID: 440770 [Multi-domain]  Cd Length: 462  Bit Score: 117.55  E-value: 4.91e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  21 VHGVSGPVVTACDMAGAAMYELVRV---GHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLR-TGKPLSVELGPGIMG 96
Cdd:COG1156     9 ISEIAGPLLFVEGVEGVGYGELVEIelpDGERRRGQVLEVSEDKAVVQVFEGTTGLSLKNTKVRfLGEPLELPVSEDMLG 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  97 AIFDGIQRP---LSDISSQTQsiyipRGVNVSAL---SRDIKWEFIPsknlrvgshiTGgdIYGIVNENSLIK-HKimLP 169
Cdd:COG1156    89 RVFNGLGRPidgGPPIIPEKR-----LDINGSPInpvAREYPREFIQ----------TG--ISAIDGLNTLVRgQK--LP 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 170 -------PRNRgsvtyIAppgnydasdvvlelefegvkekfsmVQVwpVRQVRpvteklpanhplltgqrvldalfpcVQ 242
Cdd:COG1156   150 ifsgsglPHNE-----LA-------------------------AQI--ARQAK-------------------------VR 172
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 243 GGTtaipGAFGcgktvisqslskysnsdvIIYVGCGERGNEMSEVLRDFPEltmevdgkvESIMKRTALVANTSNMPVAA 322
Cdd:COG1156   173 GEE----EKFA------------------VVFAAMGITHDEANFFREEFEE---------TGALDRVVMFLNLADDPAIE 221
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 323 REASIYTGITLSEYFR-DMGYHV-SMMADSTSrWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKclgnpER 400
Cdd:COG1156   222 RIITPRMALTAAEYLAfEKGMHVlVILTDMTN-YCEALREISAAREEVPGRRGYPGYMYSDLASLYERAGRIK-----GR 295
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 401 EGSVSIVGAVSPPGGDFSDPVTSATLGIV--QVFwgLDKKLAQRKHFPSVNWLISYSKYM-------------RAL-DEY 464
Cdd:COG1156   296 KGSITQIPILTMPNDDITHPIPDLTGYITegQIV--LSRDLHRKGIYPPIDVLPSLSRLMkdgigegktredhADVaNQL 373
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1279489789 465 YDKHftefvplrTKAKeilqeeeDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYT 526
Cdd:COG1156   374 YAAY--------ARGQ-------EVRELAAIVGEEALSETDKKYLKFADAFERRFVNQGFDE 420
PRK09099 PRK09099
type III secretion system ATPase; Provisional
225-545 2.12e-26

type III secretion system ATPase; Provisional


Pssm-ID: 169656 [Multi-domain]  Cd Length: 441  Bit Score: 112.55  E-value: 2.12e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 225 HPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEmsevLRDFPELTMEVDGkves 304
Cdd:PRK09099  145 APLPTGVRIVDGLMTLGEGQRMGIFAPAGVGKSTLMGMFARGTQCDVNVIALIGERGRE----VREFIELILGEDG---- 216
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 305 iMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLAS 384
Cdd:PRK09099  217 -MARSVVVCATSDRSSIERAKAAYVATAIAEYFRDRGLRVLLMMDSLTRFARAQREIGLAAGEPPARRGFPPSVFAELPR 295
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 385 FYERAGRvkclgnpEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEy 464
Cdd:PRK09099  296 LLERAGM-------GETGSITALYTVLAEDESGSDPIAEEVRGILDGHMILSREIAARNQYPAIDVLGSLSRVMPQVVP- 367
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 465 yDKHFTEFVPLRtkakEILQEEEDLAEIVQL---------VGKASLAETDKItlevaklikDDFLQQngytPYDRFCPFY 535
Cdd:PRK09099  368 -REHVQAAGRLR----QLLAKHREVETLLQVgeyragsdpVADEAIAKIDAI---------RDFLSQ----RTDEYSDPD 429
                         330
                  ....*....|
gi 1279489789 536 KTVGMLSNMI 545
Cdd:PRK09099  430 ATLAALAELS 439
fliI PRK08972
flagellar protein export ATPase FliI;
215-458 7.33e-26

flagellar protein export ATPase FliI;


Pssm-ID: 181599 [Multi-domain]  Cd Length: 444  Bit Score: 110.95  E-value: 7.33e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 215 RPVTEklpanhPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIyVG-CGERGNEMSEvlrdFPE 293
Cdd:PRK08972  140 RPITE------PLDVGVRAINAMLTVGKGQRMGLFAGSGVGKSVLLGMMTRGTTADVIV-VGlVGERGREVKE----FIE 208
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 294 LTMEVDGKVESIMkrTALVANTSN-MPVAAREasiyTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADS 372
Cdd:PRK08972  209 EILGEEGRARSVV--VAAPADTSPlMRLKGCE----TATTIAEYFRDQGLNVLLLMDSLTRYAQAQREIALAVGEPPATK 282
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 373 GYPAYLGARLASFYERAGRvkclGNPeREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLI 452
Cdd:PRK08972  283 GYPPSVFAKLPALVERAGN----GGP-GQGSITAFYTVLTEGDDLQDPIADASRAILDGHIVLSRELADSGHYPAIDIEA 357

                  ....*.
gi 1279489789 453 SYSKYM 458
Cdd:PRK08972  358 SISRVM 363
fliI PRK07960
flagellum-specific ATP synthase FliI;
219-465 3.46e-24

flagellum-specific ATP synthase FliI;


Pssm-ID: 181182 [Multi-domain]  Cd Length: 455  Bit Score: 106.02  E-value: 3.46e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 219 EKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEmsevLRDFPELTMEV 298
Cdd:PRK07960  151 QRTPIEHVLDTGVRAINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTQADVIVVGLIGERGRE----VKDFIENILGA 226
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 299 DGKVESIMkrTALVANTSNMpVAAREASIYTGItlSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYL 378
Cdd:PRK07960  227 EGRARSVV--IAAPADVSPL-LRMQGAAYATRI--AEDFRDRGQHVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSV 301
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 379 GARLASFYERAGRVKCLGnpereGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYM 458
Cdd:PRK07960  302 FAKLPALVERAGNGISGG-----GSITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAM 376

                  ....*....
gi 1279489789 459 RAL--DEYY 465
Cdd:PRK07960  377 TALidEQHY 385
fliI PRK06002
flagellar protein export ATPase FliI;
225-456 6.03e-24

flagellar protein export ATPase FliI;


Pssm-ID: 235666 [Multi-domain]  Cd Length: 450  Bit Score: 105.08  E-value: 6.03e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 225 HPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEmsevLRDFPELTMevdgkVES 304
Cdd:PRK06002  147 TGLRTGVRVIDIFTPLCAGQRIGIFAGSGVGKSTLLAMLARADAFDTVVIALVGERGRE----VREFLEDTL-----ADN 217
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 305 IMKRTALVANTSNMPVAAREASIyTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLAS 384
Cdd:PRK06002  218 LKKAVAVVATSDESPMMRRLAPL-TATAIAEYFRDRGENVLLIVDSVTRFAHAAREVALAAGEPPVARGYPPSVFSELPR 296
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1279489789 385 FYERAGrvkclgnPEREGSVSIVG--AVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSK 456
Cdd:PRK06002  297 LLERAG-------PGAEGGGSITGifSVLVDGDDHNDPVADSIRGTLDGHIVLDRAIAEQGRYPAVDPLASISR 363
F1-ATPase_beta_CD cd01133
F1 ATP synthase beta subunit, central domain; The F-ATPase is found in bacterial plasma ...
206-463 1.25e-23

F1 ATP synthase beta subunit, central domain; The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to drive ATP synthesis and hydrolyzes ATP to build the proton gradient. The mitochondrial extrinsic membrane domain, F1, is composed of alpha, beta, gamma, delta and epsilon subunits with a stoichiometry of 3:3:1:1:1. The beta subunit of ATP synthase is catalytic. Alpha and beta subunits form the globular catalytic moiety, a hexameric ring of alternating alpha and beta subunits. Gamma, delta and epsilon subunits form a stalk, connecting F1 to F0, the integral membrane proton-translocating domain.


Pssm-ID: 410877 [Multi-domain]  Cd Length: 277  Bit Score: 101.14  E-value: 1.25e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 206 VQVWPVRQVRP-VTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSL----SKySNSDVIIYVGCGER 280
Cdd:cd01133    29 KERWPIHREAPeFVELSTEQEILETGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELinniAK-AHGGYSVFAGVGER 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 281 GNEMSEVLRDFpeltmeVDGKVESI--MKRTALVANTSNMPVAAREASIYTGITLSEYFRDM-GYHVSMMADSTSRWAEA 357
Cdd:cd01133   108 TREGNDLYHEM------KESGVINLdgLSKVALVYGQMNEPPGARARVALTGLTMAEYFRDEeGQDVLLFIDNIFRFTQA 181
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 358 LREISGRLAEMPADSGYPAYLGARLASFYERAGRVKclgnperEGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDK 437
Cdd:cd01133   182 GSEVSALLGRIPSAVGYQPTLATEMGSLQERITSTK-------KGSITSVQAVYVPADDLTDPAPATTFAHLDATTVLSR 254
                         250       260
                  ....*....|....*....|....*.
gi 1279489789 438 KLAQRKHFPSVNWLISYSkymRALDE 463
Cdd:cd01133   255 GIAELGIYPAVDPLDSTS---RILDP 277
fliI PRK07196
flagellar protein export ATPase FliI;
213-546 2.50e-23

flagellar protein export ATPase FliI;


Pssm-ID: 180875 [Multi-domain]  Cd Length: 434  Bit Score: 103.05  E-value: 2.50e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 213 QVRPVtEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEmsevLRDFP 292
Cdd:PRK07196  126 QIHPL-QRRAVDTPLDVGVNAINGLLTIGKGQRVGLMAGSGVGKSVLLGMITRYTQADVVVVGLIGERGRE----VKEFI 200
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 293 ELTMEVDGkvesiMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADS 372
Cdd:PRK07196  201 EHSLQAAG-----MAKSVVVAAPADESPLMRIKATELCHAIATYYRDKGHDVLLLVDSLTRYAMAQREIALSLGEPPATK 275
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 373 GYPAYLGARLASFYERAgrvkclGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLI 452
Cdd:PRK07196  276 GYPPSAFSIIPRLAESA------GNSSGNGTMTAIYTVLAEGDDQQDPIVDCARAVLDGHIVLSRKLAEAGHYPAIDISQ 349
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 453 SYSKYMRALDEyydkhfTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAE--TDKITLEVAKLikDDFLQQNGYTPydr 530
Cdd:PRK07196  350 SISRCMSQVIG------SQQAKAASLLKQCYADYMAIKPLIPLGGYVAGADpmADQAVHYYPAI--TQFLRQEVGHP--- 418
                         330
                  ....*....|....*.
gi 1279489789 531 fCPFYKTVGMLSNMIS 546
Cdd:PRK07196  419 -ALFSASVEQLTGMFP 433
fliI PRK05688
flagellar protein export ATPase FliI;
222-458 3.80e-23

flagellar protein export ATPase FliI;


Pssm-ID: 168181 [Multi-domain]  Cd Length: 451  Bit Score: 102.89  E-value: 3.80e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 222 PANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEvlrdFPELTMEVDGk 301
Cdd:PRK05688  147 PISEPLDVGIRSINGLLTVGRGQRLGLFAGTGVGKSVLLGMMTRFTEADIIVVGLIGERGREVKE----FIEHILGEEG- 221
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 302 vesiMKRTALVANTSN-MPVAAREASIYTgITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGA 380
Cdd:PRK05688  222 ----LKRSVVVASPADdAPLMRLRAAMYC-TRIAEYFRDKGKNVLLLMDSLTRFAQAQREIALAIGEPPATKGYPPSVFA 296
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1279489789 381 RLASFYERAgrvkclGNPER-EGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYM 458
Cdd:PRK05688  297 KLPKLVERA------GNAEPgGGSITAFYTVLSEGDDQQDPIADSARGVLDGHIVLSRRLAEEGHYPAIDIEASISRVM 369
V_A-ATPase_B cd01135
V/A-type ATP synthase subunit B; V/A-type ATP synthase (non-catalytic) subunit B. These ...
262-459 2.42e-21

V/A-type ATP synthase subunit B; V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. Vacuolar (V-type) ATPases play major roles in endomembrane and plasma membrane proton transport in eukaryotes. They are found in multiple intracellular membranes including vacuoles, endosomes, lysosomes, Golgi-derived vesicles, secretory vesicles, as well as the plasma membrane. Archaea have a protein which is similar in sequence to V-ATPases, but functions like an F-ATPase (called A-ATPase). A similar protein is also found in a few bacteria. This subfamily consists of the non-catalytic beta subunit.


Pssm-ID: 410879 [Multi-domain]  Cd Length: 282  Bit Score: 94.60  E-value: 2.42e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 262 SLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMevdgkvesiMKRTALVANTSNMPVAAReasIYT---GITLSEYFR 338
Cdd:cd01135    94 GVVGSEENFAIVFAAMGVTMEEARFFKDDFEETGA---------LERVVLFLNLANDPTIER---IITprmALTTAEYLA 161
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 339 -DMGYHV-SMMADSTSrWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKclgnpEREGSVSIVGAVSPPGGD 416
Cdd:cd01135   162 yEKGKHVlVILTDMTN-YAEALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRVE-----GRKGSITQIPILTMPNDD 235
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1279489789 417 FSDPVTSATLGIV--QVFwgLDKKLAQRKHFPSVNWLISYSKYMR 459
Cdd:cd01135   236 ITHPIPDLTGYITegQIY--LDRDLHNKGIYPPIDVLPSLSRLMK 278
atpB CHL00060
ATP synthase CF1 beta subunit
229-522 3.57e-20

ATP synthase CF1 beta subunit


Pssm-ID: 214349 [Multi-domain]  Cd Length: 494  Bit Score: 93.95  E-value: 3.57e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 229 TGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSL----SKySNSDVIIYVGCGER---GN----EMSE----VLRDFPE 293
Cdd:CHL00060  147 TGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELinniAK-AHGGVSVFGGVGERtreGNdlymEMKEsgviNEQNIAE 225
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 294 ltmevdGKVesimkrtALVANTSNMPVAAREASIYTGITLSEYFRDMGYH-VSMMADSTSRWAEALREISGRLAEMPADS 372
Cdd:CHL00060  226 ------SKV-------ALVYGQMNEPPGARMRVGLTALTMAEYFRDVNKQdVLLFIDNIFRFVQAGSEVSALLGRMPSAV 292
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 373 GYPAYLGARLASFYERAGRVKclgnperEGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLI 452
Cdd:CHL00060  293 GYQPTLSTEMGSLQERITSTK-------EGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLD 365
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1279489789 453 SYSKYMRAL---DEYYDkhftefvpLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIkDDFLQQ 522
Cdd:CHL00060  366 STSTMLQPRivgEEHYE--------TAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKI-ERFLSQ 429
fliI PRK06793
flagellar protein export ATPase FliI;
143-458 5.86e-19

flagellar protein export ATPase FliI;


Pssm-ID: 180696 [Multi-domain]  Cd Length: 432  Bit Score: 89.65  E-value: 5.86e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 143 VGSHITGGDIYGIVNENSlikhkiMLPPRNRG-------SVTYIA-----PPGNY------DASDVVLELEFEGVKEKFS 204
Cdd:PRK06793   48 VGEHNVLCEVIAIEKENN------MLLPFEQTekvcygdSVTLIAedvviPRGNHllgkvlSANGEVLNEEAENIPLQKI 121
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 205 MVQVWPVRQVrpvtEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEM 284
Cdd:PRK06793  122 KLDAPPIHAF----EREEITDVFETGIKSIDSMLTIGIGQKIGIFAGSGVGKSTLLGMIAKNAKADINVISLVGERGREV 197
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 285 SEVLRDfpELTmevdgkvESIMKRTALVANTSNMP--VAAREASIYTGItlSEYFRDMGYHVSMMADSTSRWAEALREIS 362
Cdd:PRK06793  198 KDFIRK--ELG-------EEGMRKSVVVVATSDEShlMQLRAAKLATSI--AEYFRDQGNNVLLMMDSVTRFADARRSVD 266
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 363 GRLAEMPAdSGYPAYLGARLASFYERAGRVKclgnperEGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQR 442
Cdd:PRK06793  267 IAVKELPI-GGKTLLMESYMKKLLERSGKTQ-------KGSITGIYTVLVDGDDLNGPVPDLARGILDGHIVLKRELATL 338
                         330
                  ....*....|....*.
gi 1279489789 443 KHFPSVNWLISYSKYM 458
Cdd:PRK06793  339 SHYPAISVLDSVSRIM 354
fliI PRK08472
flagellar protein export ATPase FliI;
224-545 1.75e-18

flagellar protein export ATPase FliI;


Pssm-ID: 181439 [Multi-domain]  Cd Length: 434  Bit Score: 88.20  E-value: 1.75e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 224 NHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEvlrdFPELTMevDGKVE 303
Cdd:PRK08472  138 DEVFSVGVKSIDGLLTCGKGQKLGIFAGSGVGKSTLMGMIVKGCLAPIKVVALIGERGREIPE----FIEKNL--GGDLE 211
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 304 SimkrTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLA 383
Cdd:PRK08472  212 N----TVIVVATSDDSPLMRKYGAFCAMSVAEYFKNQGLDVLFIMDSVTRFAMAQREIGLALGEPPTSKGYPPSVLSLLP 287
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 384 SFYERAgrvkclGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRalDE 463
Cdd:PRK08472  288 QLMERA------GKEEGKGSITAFFTVLVEGDDMSDPIADQSRSILDGHIVLSRELTDFGIYPPINILNSASRVMN--DI 359
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 464 YYDKHFTEFVPLRtKAKEILQEEEDLAEIvqlvgKASLAETDKiTLEVA---KLIKDDFLQQNGYTPYdrfcPFYKTVGM 540
Cdd:PRK08472  360 ISPEHKLAARKFK-RLYSLLKENEVLIRI-----GAYQKGNDK-ELDEAiskKEFMEQFLKQNPNELF----PFEQTFEQ 428

                  ....*
gi 1279489789 541 LSNMI 545
Cdd:PRK08472  429 LEEIL 433
V-ATPase_V1_B TIGR01040
V-type (H+)-ATPase V1, B subunit; This models eukaryotic vacuolar (H+)-ATPase that is ...
306-525 2.22e-18

V-type (H+)-ATPase V1, B subunit; This models eukaryotic vacuolar (H+)-ATPase that is responsible for acidifying cellular compartments. This enzyme shares extensive sequence similarity with archaeal ATP synthase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273410 [Multi-domain]  Cd Length: 466  Bit Score: 88.24  E-value: 2.22e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 306 MKRTALVANTSNMPVAAREASIYTGITLSEYFR-DMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLAS 384
Cdd:TIGR01040 210 MERVCLFLNLANDPTIERIITPRLALTTAEYLAyQCEKHVLVILTDMSSYADALREVSAAREEVPGRRGFPGYMYTDLAT 289
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 385 FYERAGRVKclgnpEREGSVSIVGAVSPPGGDFSDPVTSATLGIV--QVFwgLDKKLAQRKHFPSVNWLISYSKYMR-AL 461
Cdd:TIGR01040 290 IYERAGRVE-----GRNGSITQIPILTMPNDDITHPIPDLTGYITegQIY--VDRQLHNRQIYPPINVLPSLSRLMKsAI 362
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1279489789 462 DEYYDKHFTEFVPLRTKAKEILQeeEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGY 525
Cdd:TIGR01040 363 GEGMTRKDHSDVSNQLYACYAIG--KDVQAMKAVVGEEALSSEDLLYLEFLDKFEKNFIAQGPY 424
PRK05922 PRK05922
type III secretion system ATPase; Validated
216-545 1.13e-17

type III secretion system ATPase; Validated


Pssm-ID: 102061 [Multi-domain]  Cd Length: 434  Bit Score: 85.73  E-value: 1.13e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 216 PVTEKLPanhpllTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELT 295
Cdd:PRK05922  136 PIQEIFP------TGIKAIDAFLTLGKGQRIGVFSEPGSGKSSLLSTIAKGSKSTINVIALIGERGREVREYIEQHKEGL 209
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 296 MEvdgkvesimKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYP 375
Cdd:PRK05922  210 AA---------QRTIIIASPAHETAPTKVIAGRAAMTIAEYFRDQGHRVLFIMDSLSRWIAALQEVALARGETLSAHHYA 280
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 376 AYLGARLASFYERAgrvkclGNPEReGSVSIVGAV--SPPGGD-FSDPVTSATLGivQVFWGldkklAQRKHF--PSVNW 450
Cdd:PRK05922  281 ASVFHHVSEFTERA------GNNDK-GSITALYAIlhYPNHPDiFTDYLKSLLDG--HFFLT-----PQGKALasPPIDI 346
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 451 LISYSKYMRALDeyYDKHFTEFVPLRTkakeILQEEEDLAEIVQLvgKASLAETDKITLEVAKLIKD--DFLQQngytPY 528
Cdd:PRK05922  347 LTSLSRSARQLA--LPHHYAAAEELRS----LLKAYHEALDIIQL--GAYVPGQDAHLDRAVKLLPSikQFLSQ----PL 414
                         330
                  ....*....|....*..
gi 1279489789 529 DRFCPFYKTVGMLSNMI 545
Cdd:PRK05922  415 SSYCALHNTLKQLEALL 431
PRK13343 PRK13343
F0F1 ATP synthase subunit alpha; Provisional
34-402 1.90e-15

F0F1 ATP synthase subunit alpha; Provisional


Pssm-ID: 183987 [Multi-domain]  Cd Length: 502  Bit Score: 79.19  E-value: 1.90e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  34 MAGAAMYELVRV--GHSELVGEiirLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDiss 111
Cdd:PRK13343   44 LPDAALDELLRFegGSRGFAFN---LEEELVGAVLLDDTADILAGTEVRRTGRVLEVPVGDGLLGRVIDPLGRPLDG--- 117
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 112 qtqsiyiprgvnvsalsrdikwefipsknlrvgshitGGDiygivnenslikhkimLPPRNRGSVTYIAPPgnydasdvV 191
Cdd:PRK13343  118 -------------------------------------GGP----------------LQATARRPLERPAPA--------I 136
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 192 LElefegvkekfsmvqvwpvRQvrPVTEklpanhPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKT------VISQSlsk 265
Cdd:PRK13343  137 IE------------------RD--FVTE------PLQTGIKVVDALIPIGRGQRELIIGDRQTGKTaiaidaIINQK--- 187
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 266 ysNSDVI-IYVGCGERGNEMSEVLRdfpelTMEVDGKvesiMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHV 344
Cdd:PRK13343  188 --DSDVIcVYVAIGQKASAVARVIE-----TLREHGA----LEYTTVVVAEASDPPGLQYLAPFAGCAIAEYFRDQGQDA 256
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1279489789 345 SMMADSTSRWAEALREISGRLAEMPADSGYPA---YLGARLasfYERAGRVkclgNPEREG 402
Cdd:PRK13343  257 LIVYDDLSKHAAAYRELSLLLRRPPGREAYPGdifYLHSRL---LERAAKL----SPELGG 310
F1-ATPase_alpha_CD cd01132
F1 ATP synthase alpha subunit, central domain; The F-ATPase is found in bacterial plasma ...
222-456 2.09e-15

F1 ATP synthase alpha subunit, central domain; The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to drive ATP synthesis and hydrolyzes ATP to build the proton gradient. The mitochondrial extrinsic membrane domain, F1, is composed of alpha, beta, gamma, delta and epsilon subunits with a stoichiometry of 3:3:1:1:1. The alpha subunit of the F1 ATP synthase can bind nucleotides, but is non-catalytic. Alpha and beta subunits form the globular catalytic moiety, a hexameric ring of alternating alpha and beta subunits. Gamma, delta and epsilon subunits form a stalk, connecting F1 to F0, the integral membrane proton-translocating domain.


Pssm-ID: 410876 [Multi-domain]  Cd Length: 274  Bit Score: 76.83  E-value: 2.09e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 222 PANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKT------VISQSlskysNSDVI-IYVGCGERGNEMSEVLRdfpel 294
Cdd:cd01132    48 SVNEPLQTGIKAIDSLIPIGRGQRELIIGDRQTGKTaiaidtIINQK-----GKKVYcIYVAIGQKRSTVAQIVK----- 117
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 295 TMEVDGKvesiMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGY 374
Cdd:cd01132   118 TLEEHGA----MEYTIVVAATASDPAPLQYLAPYAGCAMGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAY 193
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 375 PA---YLGARLasfYERAGRvkcLGNPEREGSVSIVGAVSPPGGDFSD--P--VTSATLGivQVFwgLDKKLAQRKHFPS 447
Cdd:cd01132   194 PGdvfYLHSRL---LERAAK---LSDELGGGSLTALPIIETQAGDVSAyiPtnVISITDG--QIF--LESELFNKGIRPA 263

                  ....*....
gi 1279489789 448 VNWLISYSK 456
Cdd:cd01132   264 INVGLSVSR 272
ATP-synt_ab_N pfam02874
ATP synthase alpha/beta family, beta-barrel domain; This family includes the ATP synthase ...
21-83 2.63e-14

ATP synthase alpha/beta family, beta-barrel domain; This family includes the ATP synthase alpha and beta subunits the ATP synthase associated with flagella.


Pssm-ID: 427029 [Multi-domain]  Cd Length: 69  Bit Score: 67.96  E-value: 2.63e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1279489789  21 VHGVSGPVVTACDMAGAA--MYELVRVGHSE----LVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTG 83
Cdd:pfam02874   1 IVQVIGPVVDVEFGIGRLpgLLNALEVELVEfgslVLGEVLNLGGDKVRVQVFGGTSGLSRGDEVKRTG 69
PTZ00185 PTZ00185
ATPase alpha subunit; Provisional
217-456 3.52e-13

ATPase alpha subunit; Provisional


Pssm-ID: 140212 [Multi-domain]  Cd Length: 574  Bit Score: 72.38  E-value: 3.52e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 217 VTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVIS------------QSLSKysNSDVIIYVGCGERGNEM 284
Cdd:PTZ00185  163 IVSRSPVNYNLLTGFKAVDTMIPIGRGQRELIVGDRQTGKTSIAvstiinqvrinqQILSK--NAVISIYVSIGQRCSNV 240
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 285 SEVLRDFpeltmevdgKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGR 364
Cdd:PTZ00185  241 ARIHRLL---------RSYGALRYTTVMAATAAEPAGLQYLAPYSGVTMGEYFMNRGRHCLCVYDDLSKQAVAYRQISLL 311
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 365 LAEMPADSGYPA---YLGARLasfYERAGRvkcLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQ 441
Cdd:PTZ00185  312 LRRPPGREAYPGdvfYLHSRL---LERAAM---LSPGKGGGSVTALPIVETLSNDVTAYIVTNVISITDGQIYLDTKLFT 385
                         250
                  ....*....|....*
gi 1279489789 442 RKHFPSVNWLISYSK 456
Cdd:PTZ00185  386 GGQRPAVNIGLSVSR 400
atpA CHL00059
ATP synthase CF1 alpha subunit
215-432 1.59e-12

ATP synthase CF1 alpha subunit


Pssm-ID: 176999 [Multi-domain]  Cd Length: 485  Bit Score: 69.99  E-value: 1.59e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 215 RPVTEklpanhPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVIS-QSLSKYSNSDVI-IYVGCGERGNEMSEVLRDFP 292
Cdd:CHL00059  119 RSVYE------PLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVAtDTILNQKGQNVIcVYVAIGQKASSVAQVVTTLQ 192
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 293 EltmevdgkvESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADS 372
Cdd:CHL00059  193 E---------RGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYRGRHTLIIYDDLSKQAQAYRQMSLLLRRPPGRE 263
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1279489789 373 GYPA---YLGARLasfYERAGRvkcLGNPEREGSVSIVGAVSPPGGDFSD--P--VTSATLGivQVF 432
Cdd:CHL00059  264 AYPGdvfYLHSRL---LERAAK---LSSQLGEGSMTALPIVETQAGDVSAyiPtnVISITDG--QIF 322
ATP-synt_F1_V1_A1_AB_FliI_N cd01426
ATP synthase, alpha/beta subunits of F1/V1/A1 complex, flagellum-specific ATPase FliI, ...
19-84 4.92e-12

ATP synthase, alpha/beta subunits of F1/V1/A1 complex, flagellum-specific ATPase FliI, N-terminal domain; The alpha and beta (or A and B) subunits are primarily found in the F1, V1, and A1 complexes of the F-, V- and A-type family of ATPases with rotary motors. These ion-transporting rotary ATPases are composed of two linked multi-subunit complexes: the F1, V1, or A1 complex which contains three copies each of the alpha and beta subunits that form the soluble catalytic core involved in ATP synthesis/hydrolysis, and the Fo, Vo, or Ao complex which forms the membrane-embedded proton pore. The F-ATP synthases (also called FoF1-ATPases) are found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts, or in the plasma membranes of bacteria. F-ATPases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis. The A-ATP synthases (AoA1-ATPases), a different class of proton-translocating ATP synthases, are found in archaea and function like F-ATP synthases. Structurally, however, the A-ATP synthases are more closely related to the V-ATP synthases (vacuolar VoV1-ATPases), which are a proton-translocating ATPase responsible for acidification of eukaryotic intracellular compartments and for ATP synthesis in archaea and some eubacteria. Collectively, F-, V-, and A-type synthases can function in both ATP synthesis and hydrolysis modes. This family also includes the flagellum-specific ATPase/type III secretory pathway virulence-related protein, which shows extensive similarity to the alpha and beta subunits of F1-ATP synthase.


Pssm-ID: 349738 [Multi-domain]  Cd Length: 73  Bit Score: 61.56  E-value: 4.92e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1279489789  19 GYVHGVSGPVVTACDMAGAAMYELVRVGHS------ELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGK 84
Cdd:cd01426     2 GRVIRVNGPLVEAELEGEVAIGEVCEIERGdgnnetVLKAEVIGFRGDRAILQLFESTRGLSRGALVEPTGR 73
PRK02118 PRK02118
V-type ATP synthase subunit B; Provisional
36-425 2.41e-11

V-type ATP synthase subunit B; Provisional


Pssm-ID: 179373 [Multi-domain]  Cd Length: 436  Bit Score: 66.21  E-value: 2.41e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789  36 GAAMYELVRV--GHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLsDISSQT 113
Cdd:PRK02118   22 GVGYGELATVerKDGSSLAQVIRLDGDKVTLQVFGGTRGISTGDEVVFLGRPMQVTYSESLLGRRFNGSGKPI-DGGPEL 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 114 QSIYIP-RGVNVSALSRdikweFIPSKNLRVGshITGGDIYgivneNSLIKhkimlpprnrgsvtyiappgnydasdvvl 192
Cdd:PRK02118  101 EGEPIEiGGPSVNPVKR-----IVPREMIRTG--IPMIDVF-----NTLVE----------------------------- 139
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 193 elefegvkekfsmvqvwpvrqvrpvTEKLPanhplltgqrvldaLFpcvqggttAIPGafgcgkTVISQSLSKYSN---S 269
Cdd:PRK02118  140 -------------------------SQKIP--------------IF--------SVSG------EPYNALLARIALqaeA 166
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 270 DVIIYVGCGERGNEMSEVLRDFPELtmevdgkveSIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYH--VSMM 347
Cdd:PRK02118  167 DIIILGGMGLTFDDYLFFKDTFENA---------GALDRTVMFIHTASDPPVECLLVPDMALAVAEKFALEGKKkvLVLL 237
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1279489789 348 ADSTSrWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVkclgnpEREGSVSIVGAVSPPGGDFSDPVTSAT 425
Cdd:PRK02118  238 TDMTN-FADALKEISITMDQIPSNRGYPGSLYSDLASRYEKAVDF------EDGGSITIIAVTTMPGDDVTHPVPDNT 308
PRK09281 PRK09281
F0F1 ATP synthase subunit alpha; Validated
212-392 1.41e-08

F0F1 ATP synthase subunit alpha; Validated


Pssm-ID: 236448 [Multi-domain]  Cd Length: 502  Bit Score: 57.38  E-value: 1.41e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 212 RQvrPVTEklpanhPLLTGQRVLDALFPCVQG-----------GTTAIpgafgCGKTVISQSlskysNSDVI-IYVGCGE 279
Cdd:PRK09281  139 RK--SVHE------PLQTGIKAIDAMIPIGRGqreliigdrqtGKTAI-----AIDTIINQK-----GKDVIcIYVAIGQ 200
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1279489789 280 RGNEMSEVLRdfpelTMEVDGKvesiMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALR 359
Cdd:PRK09281  201 KASTVAQVVR-----KLEEHGA----MEYTIVVAATASDPAPLQYLAPYAGCAMGEYFMDNGKDALIVYDDLSKQAVAYR 271
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1279489789 360 EIS-------GRLAempadsgYPA---YLGARLasfYERAGRV 392
Cdd:PRK09281  272 QLSlllrrppGREA-------YPGdvfYLHSRL---LERAAKL 304
ATP-synt_F1_V1_A1_AB_FliI_C cd01429
ATP synthase, alpha/beta subunits of F1/V1/A1 complex, flagellum-specific ATPase FliI, ...
480-541 5.13e-06

ATP synthase, alpha/beta subunits of F1/V1/A1 complex, flagellum-specific ATPase FliI, C-terminal domain; The alpha and beta (also called A and B) subunits are primarily found in the F1, V1, and A1 complexes of F-, V- and A-type family of ATPases with rotary motors. These ion-transporting rotary ATPases are composed of two linked multi-subunit complexes: the F1, V1, and A1 complexes contain three copies each of the alpha and beta subunits that form the soluble catalytic core, which is involved in ATP synthesis/hydrolysis, and the Fo, Vo, or Ao complex that forms the membrane-embedded proton pore. The F-ATP synthases (also called FoF1-ATPases) are found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts, or in the plasma membranes of bacteria. F-ATPases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis. The A-ATP synthases (AoA1-ATPases), a different class of proton-translocating ATP synthases, are found in archaea and function like F-ATP synthases. Structurally, however, the A-ATP synthases are more closely related to the V-ATP synthases (vacuolar VoV1-ATPases), which are a proton-translocating ATPase responsible for acidification of eukaryotic intracellular compartments and for ATP synthesis in archaea and some eubacteria. Collectively, F-, V-, and A-type synthases can function in both ATP synthesis and hydrolysis modes. This family also includes the flagellum-specific ATPase/type III secretory pathway virulence-related protein, which shows extensive similarity to the alpha and beta subunits of F1-ATP synthase.


Pssm-ID: 349744 [Multi-domain]  Cd Length: 70  Bit Score: 44.36  E-value: 5.13e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1279489789 480 KEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKdDFLQQNGYTPYdrfcPFYKTVGML 541
Cdd:cd01429     9 KAILAQYRELRDIVAIVGDDALSEADKKTLSRGRRLE-EFLQQGQFEPE----TIEDTLEKL 65
ATP-synt_V_A-type_beta_N cd18118
V/A-type ATP synthase beta (B) subunit, N-terminal domain; The beta (B) subunit of the V1/A1 ...
21-84 1.47e-05

V/A-type ATP synthase beta (B) subunit, N-terminal domain; The beta (B) subunit of the V1/A1 complexes of V/A-type ATP synthases, N-terminal domain. The V- and A-type family of ATPases are composed of two linked multi-subunit complexes: the V1 or A1 complex which contains three copies each of the alpha and beta subunits that form the soluble catalytic core, that is involved in ATP synthesis/hydrolysis, and the Vo or Ao complex which forms the membrane-embedded proton pore. The A-ATP synthase (AoA1-ATPase) is found in archaea and functions like F-ATP synthase. Structurally, however, the A-ATP synthase is more closely related to the V-ATP synthase (vacuolar VoV1-ATPase), which is a proton-translocating ATPase responsible for acidification of eukaryotic intracellular compartments and for ATP synthesis in archaea and some eubacteria. Collectively, the V- and A-type synthases can function in both ATP synthesis and hydrolysis modes. This subfamily consists of the non-catalytic beta subunit.


Pssm-ID: 349742 [Multi-domain]  Cd Length: 72  Bit Score: 43.19  E-value: 1.47e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1279489789  21 VHGVSGPVVTACDMAGAAMYELVRV----GHSELvGEIIRLEGDMATIQVYEETSGVSVGDPVLR-TGK 84
Cdd:cd18118     5 VSEINGPLVIVEGVKGVKYGEIVEItlpdGEVRR-GQVLEVSGDKAVVQVFEGTSGLDLKGTKVRfTGE 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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