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Conserved domains on  [gi|939106583|ref|NP_001303278|]
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thrombospondin type-1 domain-containing protein 7B precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 602-660 3.01e-14

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


:

Pssm-ID: 465948  Cd Length: 52  Bit Score: 68.46  E-value: 3.01e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 939106583   602 CVLSEWTEWSSCSQSCsnknSDGKQTRSRTILALAGEGGKPCPPsqaLQEHRLCNDHSC 660
Cdd:pfam19028    1 CVVSEWSEWSECSVTC----GGGVQTRTRTVIVEPQNGGRPCPE---LLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1248-1301 1.89e-13

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


:

Pssm-ID: 465948  Cd Length: 52  Bit Score: 66.15  E-value: 1.89e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 939106583  1248 CQLSGWTAWTECSQTCGhGGRMSRTRFIIMPTQGEGRPCPtELTQEKTCPVTPC 1301
Cdd:pfam19028    1 CVVSEWSEWSECSVTCG-GGVQTRTRTVIVEPQNGGRPCP-ELLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 180-229 7.92e-13

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


:

Pssm-ID: 465948  Cd Length: 52  Bit Score: 64.22  E-value: 7.92e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 939106583   180 CVVSEFLPWSNCSKGCGKKLQHRTRAVIAPPLFGGLQCPNLTESRACDAP 229
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGGVQTRTRTVIVEPQNGGRPCPELLERRPCNLP 50
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 337-388 4.69e-12

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


:

Pssm-ID: 465948  Cd Length: 52  Bit Score: 62.30  E-value: 4.69e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 939106583   337 CETSQWSSWSPCSKTCRsgsllPGFRSRSRNVKHMAIGGGKECPELLEKEAC 388
Cdd:pfam19028    1 CVVSEWSEWSECSVTCG-----GGVQTRTRTVIVEPQNGGRPCPELLERRPC 47
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1371-1430 7.87e-10

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


:

Pssm-ID: 465948  Cd Length: 52  Bit Score: 55.75  E-value: 7.87e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106583  1371 CHLTEWSEWSTCELTCidgrsfeTVGRQSRSRTFIIQSFENQDSCPQQvLETRPCTGGKC 1430
Cdd:pfam19028    1 CVVSEWSEWSECSVTC-------GGGVQTRTRTVIVEPQNGGRPCPEL-LERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 738-789 1.67e-09

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


:

Pssm-ID: 465948  Cd Length: 52  Bit Score: 54.98  E-value: 1.67e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 939106583   738 CIVTAFSEWTPCPRMCQAGnatvKQSRYRIIIQEAANGGQECPDTLyEEREC 789
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGG----VQTRTRTVIVEPQNGGRPCPELL-ERRPC 47
TSP1_ADAMTS super family cl40597
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 665-733 4.38e-07

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


The actual alignment was detected with superfamily member pfam19030:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 48.22  E-value: 4.38e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106583   665 WETSPWGPCSedtlvtalnatigwngeATCGVGIQTRRVFCVKSHVGQVMT-KRCPDSTRPETVRPCFLP 733
Cdd:pfam19030    1 WVAGPWGECS-----------------VTCGGGVQTRLVQCVQKGGGSIVPdSECSAQKKPPETQSCNLK 53
TSP1_ADAMTS super family cl40597
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 1062-1122 5.28e-07

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


The actual alignment was detected with superfamily member pfam19030:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 47.83  E-value: 5.28e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 939106583  1062 WVVEHWSSCkinnelrSLRCGGGTQSRKIRCVNTADGEggAVDSNLCNQDEIPPETQSCSL 1122
Cdd:pfam19030    1 WVAGPWGEC-------SVTCGGGVQTRLVQCVQKGGGS--IVPDSECSAQKKPPETQSCNL 52
TSP1_ADAMTS super family cl40597
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 44-95 1.05e-06

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


The actual alignment was detected with superfamily member pfam19030:

Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 47.06  E-value: 1.05e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 939106583    44 WKPGPWGRCTGDCGpGGVQSRAVWCFH-VDGWTSHLSNCGESNRPPKERSCFR 95
Cdd:pfam19030    1 WVAGPWGECSVTCG-GGVQTRLVQCVQkGGGSIVPDSECSAQKKPPETQSCNL 52
TSP1_spondin super family cl46269
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1128-1174 3.04e-06

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


The actual alignment was detected with superfamily member pfam19028:

Pssm-ID: 480609  Cd Length: 52  Bit Score: 45.73  E-value: 3.04e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 939106583  1128 CVMSEWGLWSKCPQSCDPhTMQRRTRHLLRPSLNS-RTCAEDSQVQPC 1174
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGG-GVQTRTRTVIVEPQNGgRPCPELLERRPC 47
TSP1_spondin super family cl46269
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 485-542 1.01e-05

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


The actual alignment was detected with superfamily member pfam19028:

Pssm-ID: 480609  Cd Length: 52  Bit Score: 44.19  E-value: 1.01e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 939106583   485 CIVSSWSAWGLCIHEnChdpqgKKGFRTRQRHVLMESTGPAGHCPHLVESVPCEDPMC 542
Cdd:pfam19028    1 CVVSEWSEWSECSVT-C-----GGGVQTRTRTVIVEPQNGGRPCPELLERRPCNLPPC 52
 
Name Accession Description Interval E-value
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 602-660 3.01e-14

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 68.46  E-value: 3.01e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 939106583   602 CVLSEWTEWSSCSQSCsnknSDGKQTRSRTILALAGEGGKPCPPsqaLQEHRLCNDHSC 660
Cdd:pfam19028    1 CVVSEWSEWSECSVTC----GGGVQTRTRTVIVEPQNGGRPCPE---LLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1248-1301 1.89e-13

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 66.15  E-value: 1.89e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 939106583  1248 CQLSGWTAWTECSQTCGhGGRMSRTRFIIMPTQGEGRPCPtELTQEKTCPVTPC 1301
Cdd:pfam19028    1 CVVSEWSEWSECSVTCG-GGVQTRTRTVIVEPQNGGRPCP-ELLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 180-229 7.92e-13

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 64.22  E-value: 7.92e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 939106583   180 CVVSEFLPWSNCSKGCGKKLQHRTRAVIAPPLFGGLQCPNLTESRACDAP 229
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGGVQTRTRTVIVEPQNGGRPCPELLERRPCNLP 50
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 337-388 4.69e-12

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 62.30  E-value: 4.69e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 939106583   337 CETSQWSSWSPCSKTCRsgsllPGFRSRSRNVKHMAIGGGKECPELLEKEAC 388
Cdd:pfam19028    1 CVVSEWSEWSECSVTCG-----GGVQTRTRTVIVEPQNGGRPCPELLERRPC 47
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1371-1430 7.87e-10

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 55.75  E-value: 7.87e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106583  1371 CHLTEWSEWSTCELTCidgrsfeTVGRQSRSRTFIIQSFENQDSCPQQvLETRPCTGGKC 1430
Cdd:pfam19028    1 CVVSEWSEWSECSVTC-------GGGVQTRTRTVIVEPQNGGRPCPEL-LERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 738-789 1.67e-09

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 54.98  E-value: 1.67e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 939106583   738 CIVTAFSEWTPCPRMCQAGnatvKQSRYRIIIQEAANGGQECPDTLyEEREC 789
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGG----VQTRTRTVIVEPQNGGRPCPELL-ERRPC 47
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 665-733 4.38e-07

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 48.22  E-value: 4.38e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106583   665 WETSPWGPCSedtlvtalnatigwngeATCGVGIQTRRVFCVKSHVGQVMT-KRCPDSTRPETVRPCFLP 733
Cdd:pfam19030    1 WVAGPWGECS-----------------VTCGGGVQTRLVQCVQKGGGSIVPdSECSAQKKPPETQSCNLK 53
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 1062-1122 5.28e-07

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 47.83  E-value: 5.28e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 939106583  1062 WVVEHWSSCkinnelrSLRCGGGTQSRKIRCVNTADGEggAVDSNLCNQDEIPPETQSCSL 1122
Cdd:pfam19030    1 WVAGPWGEC-------SVTCGGGVQTRLVQCVQKGGGS--IVPDSECSAQKKPPETQSCNL 52
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 44-95 1.05e-06

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 47.06  E-value: 1.05e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 939106583    44 WKPGPWGRCTGDCGpGGVQSRAVWCFH-VDGWTSHLSNCGESNRPPKERSCFR 95
Cdd:pfam19030    1 WVAGPWGECSVTCG-GGVQTRLVQCVQkGGGSIVPDSECSAQKKPPETQSCNL 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1128-1174 3.04e-06

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 45.73  E-value: 3.04e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 939106583  1128 CVMSEWGLWSKCPQSCDPhTMQRRTRHLLRPSLNS-RTCAEDSQVQPC 1174
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGG-GVQTRTRTVIVEPQNGgRPCPELLERRPC 47
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 485-542 1.01e-05

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 44.19  E-value: 1.01e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 939106583   485 CIVSSWSAWGLCIHEnChdpqgKKGFRTRQRHVLMESTGPAGHCPHLVESVPCEDPMC 542
Cdd:pfam19028    1 CVVSEWSEWSECSVT-C-----GGGVQTRTRTVIVEPQNGGRPCPELLERRPCNLPPC 52
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 1251-1301 3.27e-05

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 42.96  E-value: 3.27e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|..
gi 939106583   1251 SGWTAWTECSQTCGhGGRMSRTRFIIMPT-QGEGRPCPTELTQEKTCPVTPC 1301
Cdd:smart00209    2 SEWSEWSPCSVTCG-GGVQTRTRSCCSPPpQNGGGPCTGEDVETRACNEQPC 52
PTZ00441 PTZ00441
sporozoite surface protein 2 (SSP2); Provisional
 1202-1300 7.99e-05

sporozoite surface protein 2 (SSP2); Provisional


Pssm-ID: 240420 [Multi-domain]  Cd Length: 576  Bit Score: 47.27  E-value: 7.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106583 1202 GQGVR---TRLLS-CVCSDGKP---VSMDQCEQHNLEKPQRMSIPCLVECVVNCQLsgWTAWTECSQTCGHGGRmSRTRf 1274
Cdd:PTZ00441  187 GQGINhqfNRLLAgCRPREGKCkfySDADWEEAKNLIKPFIAKVCTEVERTASCGP--WDEWTPCSVTCGKGTH-SRSR- 262

                          90       100
                  ....*....|....*....|....*....
gi 939106583 1275 iimPTQGEGrpCPTELT---QEKTCPVTP 1300
Cdd:PTZ00441  263 ---PILHEG--CTTHMVeecEEEECPVEP 286
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 605-660 1.00e-04

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 41.42  E-value: 1.00e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 939106583    605 SEWTEWSSCSQSCSNknsdGKQTRSRT-ILALAGEGGKPCPPSQalQEHRLCNDHSC 660
Cdd:smart00209    2 SEWSEWSPCSVTCGG----GVQTRTRScCSPPPQNGGGPCTGED--VETRACNEQPC 52
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 340-391 4.18e-03

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 36.80  E-value: 4.18e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....
gi 939106583    340 SQWSSWSPCSKTCRSGSllpgfRSRSRNVK-HMAIGGGKECPEL-LEKEACIVE 391
Cdd:smart00209    2 SEWSEWSPCSVTCGGGV-----QTRTRSCCsPPPQNGGGPCTGEdVETRACNEQ 50
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 1374-1430 4.57e-03

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 36.80  E-value: 4.57e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 939106583   1374 TEWSEWSTCELTCidgrsfeTVGRQSRSRTFI-IQSFENQDSCPQQVLETRPCTGGKC 1430
Cdd:smart00209    2 SEWSEWSPCSVTC-------GGGVQTRTRSCCsPPPQNGGGPCTGEDVETRACNEQPC 52
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 182-233 7.71e-03

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 36.03  E-value: 7.71e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....
gi 939106583    182 VSEFLPWSNCSKGCGKKLQHRTRAVI-APPLFGGLQCP-NLTESRACDAPiSCP 233
Cdd:smart00209    1 WSEWSEWSPCSVTCGGGVQTRTRSCCsPPPQNGGGPCTgEDVETRACNEQ-PCP 53
 
Name Accession Description Interval E-value
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 602-660 3.01e-14

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 68.46  E-value: 3.01e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 939106583   602 CVLSEWTEWSSCSQSCsnknSDGKQTRSRTILALAGEGGKPCPPsqaLQEHRLCNDHSC 660
Cdd:pfam19028    1 CVVSEWSEWSECSVTC----GGGVQTRTRTVIVEPQNGGRPCPE---LLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1248-1301 1.89e-13

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 66.15  E-value: 1.89e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 939106583  1248 CQLSGWTAWTECSQTCGhGGRMSRTRFIIMPTQGEGRPCPtELTQEKTCPVTPC 1301
Cdd:pfam19028    1 CVVSEWSEWSECSVTCG-GGVQTRTRTVIVEPQNGGRPCP-ELLERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 180-229 7.92e-13

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 64.22  E-value: 7.92e-13
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 939106583   180 CVVSEFLPWSNCSKGCGKKLQHRTRAVIAPPLFGGLQCPNLTESRACDAP 229
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGGVQTRTRTVIVEPQNGGRPCPELLERRPCNLP 50
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 337-388 4.69e-12

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 62.30  E-value: 4.69e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 939106583   337 CETSQWSSWSPCSKTCRsgsllPGFRSRSRNVKHMAIGGGKECPELLEKEAC 388
Cdd:pfam19028    1 CVVSEWSEWSECSVTCG-----GGVQTRTRTVIVEPQNGGRPCPELLERRPC 47
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1371-1430 7.87e-10

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 55.75  E-value: 7.87e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106583  1371 CHLTEWSEWSTCELTCidgrsfeTVGRQSRSRTFIIQSFENQDSCPQQvLETRPCTGGKC 1430
Cdd:pfam19028    1 CVVSEWSEWSECSVTC-------GGGVQTRTRTVIVEPQNGGRPCPEL-LERRPCNLPPC 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 738-789 1.67e-09

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 54.98  E-value: 1.67e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 939106583   738 CIVTAFSEWTPCPRMCQAGnatvKQSRYRIIIQEAANGGQECPDTLyEEREC 789
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGGG----VQTRTRTVIVEPQNGGRPCPELL-ERRPC 47
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 665-733 4.38e-07

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 48.22  E-value: 4.38e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106583   665 WETSPWGPCSedtlvtalnatigwngeATCGVGIQTRRVFCVKSHVGQVMT-KRCPDSTRPETVRPCFLP 733
Cdd:pfam19030    1 WVAGPWGECS-----------------VTCGGGVQTRLVQCVQKGGGSIVPdSECSAQKKPPETQSCNLK 53
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 1062-1122 5.28e-07

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 47.83  E-value: 5.28e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 939106583  1062 WVVEHWSSCkinnelrSLRCGGGTQSRKIRCVNTADGEggAVDSNLCNQDEIPPETQSCSL 1122
Cdd:pfam19030    1 WVAGPWGEC-------SVTCGGGVQTRLVQCVQKGGGS--IVPDSECSAQKKPPETQSCNL 52
TSP1_ADAMTS pfam19030
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ...
 44-95 1.05e-06

Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.


Pssm-ID: 465950 [Multi-domain]  Cd Length: 55  Bit Score: 47.06  E-value: 1.05e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 939106583    44 WKPGPWGRCTGDCGpGGVQSRAVWCFH-VDGWTSHLSNCGESNRPPKERSCFR 95
Cdd:pfam19030    1 WVAGPWGECSVTCG-GGVQTRLVQCVQkGGGSIVPDSECSAQKKPPETQSCNL 52
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 1128-1174 3.04e-06

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 45.73  E-value: 3.04e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 939106583  1128 CVMSEWGLWSKCPQSCDPhTMQRRTRHLLRPSLNS-RTCAEDSQVQPC 1174
Cdd:pfam19028    1 CVVSEWSEWSECSVTCGG-GVQTRTRTVIVEPQNGgRPCPELLERRPC 47
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 485-542 1.01e-05

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 44.19  E-value: 1.01e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 939106583   485 CIVSSWSAWGLCIHEnChdpqgKKGFRTRQRHVLMESTGPAGHCPHLVESVPCEDPMC 542
Cdd:pfam19028    1 CVVSEWSEWSECSVT-C-----GGGVQTRTRTVIVEPQNGGRPCPELLERRPCNLPPC 52
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 1251-1301 3.27e-05

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 42.96  E-value: 3.27e-05
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|..
gi 939106583   1251 SGWTAWTECSQTCGhGGRMSRTRFIIMPT-QGEGRPCPTELTQEKTCPVTPC 1301
Cdd:smart00209    2 SEWSEWSPCSVTCG-GGVQTRTRSCCSPPpQNGGGPCTGEDVETRACNEQPC 52
PTZ00441 PTZ00441
sporozoite surface protein 2 (SSP2); Provisional
 1202-1300 7.99e-05

sporozoite surface protein 2 (SSP2); Provisional


Pssm-ID: 240420 [Multi-domain]  Cd Length: 576  Bit Score: 47.27  E-value: 7.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106583 1202 GQGVR---TRLLS-CVCSDGKP---VSMDQCEQHNLEKPQRMSIPCLVECVVNCQLsgWTAWTECSQTCGHGGRmSRTRf 1274
Cdd:PTZ00441  187 GQGINhqfNRLLAgCRPREGKCkfySDADWEEAKNLIKPFIAKVCTEVERTASCGP--WDEWTPCSVTCGKGTH-SRSR- 262

                          90       100
                  ....*....|....*....|....*....
gi 939106583 1275 iimPTQGEGrpCPTELT---QEKTCPVTP 1300
Cdd:PTZ00441  263 ---PILHEG--CTTHMVeecEEEECPVEP 286
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 605-660 1.00e-04

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 41.42  E-value: 1.00e-04
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*..
gi 939106583    605 SEWTEWSSCSQSCSNknsdGKQTRSRT-ILALAGEGGKPCPPSQalQEHRLCNDHSC 660
Cdd:smart00209    2 SEWSEWSPCSVTCGG----GVQTRTRScCSPPPQNGGGPCTGED--VETRACNEQPC 52
TSP_1 pfam00090
Thrombospondin type 1 domain;
1251-1301 2.22e-04

Thrombospondin type 1 domain;


Pssm-ID: 459668 [Multi-domain]  Cd Length: 49  Bit Score: 40.48  E-value: 2.22e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 939106583  1251 SGWTAWTECSQTCGHGGRMsRTRFIIMPTQGeGRPCPTELTQEKTCPVTPC 1301
Cdd:pfam00090    1 SPWSPWSPCSVTCGKGIQV-RQRTCKSPFPG-GEPCTGDDIETQACKMDKC 49
TSP_1 pfam00090
Thrombospondin type 1 domain;
605-660 1.70e-03

Thrombospondin type 1 domain;


Pssm-ID: 459668 [Multi-domain]  Cd Length: 49  Bit Score: 37.78  E-value: 1.70e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 939106583   605 SEWTEWSSCSQSCSNknsdGKQTRSRTILALAgEGGKPCPPSQalQEHRLCNDHSC 660
Cdd:pfam00090    1 SPWSPWSPCSVTCGK----GIQVRQRTCKSPF-PGGEPCTGDD--IETQACKMDKC 49
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 340-391 4.18e-03

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 36.80  E-value: 4.18e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....
gi 939106583    340 SQWSSWSPCSKTCRSGSllpgfRSRSRNVK-HMAIGGGKECPEL-LEKEACIVE 391
Cdd:smart00209    2 SEWSEWSPCSVTCGGGV-----QTRTRSCCsPPPQNGGGPCTGEdVETRACNEQ 50
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 1374-1430 4.57e-03

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 36.80  E-value: 4.57e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....*...
gi 939106583   1374 TEWSEWSTCELTCidgrsfeTVGRQSRSRTFI-IQSFENQDSCPQQVLETRPCTGGKC 1430
Cdd:smart00209    2 SEWSEWSPCSVTC-------GGGVQTRTRSCCsPPPQNGGGPCTGEDVETRACNEQPC 52
TSP_1 pfam00090
Thrombospondin type 1 domain;
340-388 6.12e-03

Thrombospondin type 1 domain;


Pssm-ID: 459668 [Multi-domain]  Cd Length: 49  Bit Score: 36.24  E-value: 6.12e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 939106583   340 SQWSSWSPCSKTCRSGSllpgfRSRSRNVKHMAIGGGKECPELLEKEAC 388
Cdd:pfam00090    1 SPWSPWSPCSVTCGKGI-----QVRQRTCKSPFPGGEPCTGDDIETQAC 44
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 182-233 7.71e-03

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 36.03  E-value: 7.71e-03
                            10        20        30        40        50
                    ....*....|....*....|....*....|....*....|....*....|....
gi 939106583    182 VSEFLPWSNCSKGCGKKLQHRTRAVI-APPLFGGLQCP-NLTESRACDAPiSCP 233
Cdd:smart00209    1 WSEWSEWSPCSVTCGGGVQTRTRSCCsPPPQNGGGPCTgEDVETRACNEQ-PCP 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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