NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|594542479|ref|NP_001277496|]
View 

tetratricopeptide repeat protein 16 isoform c [Mus musculus]

Protein Classification

TPR and NlpI domain-containing protein( domain architecture ID 12778898)

TPR and NlpI domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
235-417 4.19e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.51  E-value: 4.19e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 235 IENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMvtdtqdnlvkqaQRQLLLTYNDFAVHCYNHGAYQEGVLLLNKA 314
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL------------DPDDAEALYNLGLAYLRLGRYEEALADYEQA 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 315 IRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSP 394
Cdd:COG0457   69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELG-------RYDEAIEAYERALELDP 141

                        170       180
                 ....*....|....*....|...
gi 594542479 395 QKPQYYLHRAKCRQFLQNTLGAR 417
Cdd:COG0457  142 DDADALYNLGIALEKLGRYEEAL 164
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
15-215 8.25e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.66  E-value: 8.25e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  15 PAKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAF 94
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  95 VLYLQGqclyelcDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNF- 173
Cdd:COG0457   85 ALQALG-------RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKl 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 594542479 174 --FQKAKLCYQDLRSALLLDPLHAQAKGLLQKMVDQAKQSLQDA 215
Cdd:COG0457  158 grYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLL 201
NlpI super family cl34822
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
337-512 4.93e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG4785:

Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.21  E-value: 4.93e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 337 NLAFAEADYKQALALSPLDEGANLRM-GVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLG 415
Cdd:COG4785   53 LAAAALAAERIDRALALPDLAQLYYErGVAYDSLG-------DYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDA 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 416 ARLDVATVLLLNPEYPkmAAVMN---TLFpsmtvenvlKSQVAELAKLQLSRMIENGPKNiyPQSTVVQRLLERRKA--- 489
Cdd:COG4785  126 ALEDFDRALELDPDYA--YAYLNrgiALY---------YLGRYELAIADLEKALELDPND--PERALWLYLAERKLDpek 192

                        170       180
                 ....*....|....*....|....*..
gi 594542479 490 --QVLVKLWK--QERLGTPEEEVTLYQ 512
Cdd:COG4785  193 alALLLEDWAtaYLLQGDTEEARELFK 219
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
235-417 4.19e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.51  E-value: 4.19e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 235 IENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMvtdtqdnlvkqaQRQLLLTYNDFAVHCYNHGAYQEGVLLLNKA 314
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL------------DPDDAEALYNLGLAYLRLGRYEEALADYEQA 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 315 IRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSP 394
Cdd:COG0457   69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELG-------RYDEAIEAYERALELDP 141

                        170       180
                 ....*....|....*....|...
gi 594542479 395 QKPQYYLHRAKCRQFLQNTLGAR 417
Cdd:COG0457  142 DDADALYNLGIALEKLGRYEEAL 164
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
15-215 8.25e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.66  E-value: 8.25e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  15 PAKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAF 94
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  95 VLYLQGqclyelcDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNF- 173
Cdd:COG0457   85 ALQALG-------RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKl 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 594542479 174 --FQKAKLCYQDLRSALLLDPLHAQAKGLLQKMVDQAKQSLQDA 215
Cdd:COG0457  158 grYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLL 201
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 16-400 1.61e-10

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 64.62  E-value: 1.61e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479   16 AKVREyynQGHQCLLQEDWEMSVLFFSRALHLDPKLVdFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFV 95
Cdd:TIGR00990 128 AKLKE---KGNKAYRNKDFNKAIKLYSKAIECKPDPV-YYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANA 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479   96 LYLQGQCLYELCDFQeALCVflqasdlqpqNASFSYRCMACLLA--LKRYHDCLALITREVKQGRASADVYIlrarlYNF 173
Cdd:TIGR00990 204 YDGLGKYADALLDLT-ASCI----------IDGFRNEQSAQAVErlLKKFAESKAKEILETKPENLPSVTFV-----GNY 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  174 FQ--KAKLCYQDLRSALLLDplHAQAKGLLQK----MVDQAKQSLQDASTLAVQgkvhralkcincAIENNPLDPNFFF- 246
Cdd:TIGR00990 268 LQsfRPKPRPAGLEDSNELD--EETGNGQLQLglksPESKADESYEEAARAFEK------------ALDLGKLGEKEAIa 333

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  247 --FRGTLRRRLQQFDHAVEDFLKAMDMVTDTQDNLVKQAQRQLLLTYNDFAvhcYNHgayqegvllLNKAIRDEQNEKGL 324
Cdd:TIGR00990 334 lnLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKA---EED---------FDKALKLNSEDPDI 401

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 594542479  325 YINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYY 400
Cdd:TIGR00990 402 YYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEG-------SIASSMATFRRCKKNFPEAPDVY 470
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 64-150 8.60e-06

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 44.55  E-value: 8.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479   64 QLCDFSSALQNLRRAYSYDPGNNKYLnrlafvlYLQGQCLYELCDFQEALCVfLQASDLQPQNASFSYRCMACLLALKRY 143
Cdd:pfam12895   1 DQHQYKNAIFLAERLLAAEPESPEDA-------YLLAQCLFLNGQYKRAYEL-LRKAKLNGSSLGCRYLFAQCLLKLKKY 72


                  ....*..
gi 594542479  144 HDCLALI 150
Cdd:pfam12895  73 DEALDAL 79
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 24-129 2.86e-05

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 47.09  E-value: 2.86e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  24 QGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNK-YLNrlafvlylQGQC 102
Cdd:PLN03088   8 KAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKaYLR--------KGTA 79

                         90       100
                 ....*....|....*....|....*..
gi 594542479 103 LYELCDFQEALCVFLQASDLQPQNASF 129
Cdd:PLN03088  80 CMKLEEYQTAKAALEKGASLAPGDSRF 106
TPR_1 pfam00515
Tetratricopeptide repeat;
325-353 1.32e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 39.71  E-value: 1.32e-04
                          10        20
                  ....*....|....*....|....*....
gi 594542479  325 YINRGDCFFQLGNLAFAEADYKQALALSP 353
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNP 32
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 310-399 4.70e-04

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 43.24  E-value: 4.70e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 310 LLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEA 389
Cdd:PLN03088  24 LYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLE-------EYQTAKAALEKG 96

                         90
                 ....*....|
gi 594542479 390 IRHSPQKPQY 399
Cdd:PLN03088  97 ASLAPGDSRF 106
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
337-512 4.93e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.21  E-value: 4.93e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 337 NLAFAEADYKQALALSPLDEGANLRM-GVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLG 415
Cdd:COG4785   53 LAAAALAAERIDRALALPDLAQLYYErGVAYDSLG-------DYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDA 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 416 ARLDVATVLLLNPEYPkmAAVMN---TLFpsmtvenvlKSQVAELAKLQLSRMIENGPKNiyPQSTVVQRLLERRKA--- 489
Cdd:COG4785  126 ALEDFDRALELDPDYA--YAYLNrgiALY---------YLGRYELAIADLEKALELDPND--PERALWLYLAERKLDpek 192

                        170       180
                 ....*....|....*....|....*..
gi 594542479 490 --QVLVKLWK--QERLGTPEEEVTLYQ 512
Cdd:COG4785  193 alALLLEDWAtaYLLQGDTEEARELFK 219
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 58-124 5.47e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 42.62  E-value: 5.47e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 594542479  58 RAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLafvlylqGQCLYELCDFQEALCVFLQASDLQP 124
Cdd:cd24142    6 KAEELLDQGNFELALKFLQRALELEPNNVEALELL-------GEILLELGDVEEAREVLLRAIELDP 65
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 31-417 6.54e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.15  E-value: 6.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479   31 QEDWEMSVLFFSRALHLDPKLVdfYVFRAEAFIQLC--DFSSALQNLRRAYSYDPGNNKYLNrlafvlyLQGQCLYELCD 108
Cdd:TIGR02917 308 LGNLEQAYQYLNQILKYAPNSH--QARRLLASIQLRlgRVDEAIATLSPALGLDPDDPAALS-------LLGEAYLALGD 378

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  109 FQEALCVFLQASDLQPQNASFSYRcmaclLALKRyhdclaLITREVKQGRAsadvyilrarlyNFFQKAKLCYQDLRSAL 188
Cdd:TIGR02917 379 FEKAAEYLAKATELDPENAAARTQ-----LGISK------LSQGDPSEAIA------------DLETAAQLDPELGRADL 435

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  189 LL----------DPLHAQAKGLLQKMVDQAKQSLQDASTLAVQGKVHRALKCINCAIEnnpLDPNFFFFRGTLRRRLQQF 258
Cdd:TIGR02917 436 LLilsylrsgqfDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALS---IEPDFFPAAANLARIDIQE 512

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  259 DHAVEDFLKAMDMVTDTQDNLvkqaqrQLLLTYNDFAVHcynHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNL 338
Cdd:TIGR02917 513 GNPDDAIQRFEKVLTIDPKNL------RAILALAGLYLR---TGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQL 583

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 594542479  339 AFAEADYKQALALSPlDEGANLRMgvlqekLGFCQQKHRQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLGAR 417
Cdd:TIGR02917 584 KKALAILNEAADAAP-DSPEAWLM------LGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAI 655
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 325-353 1.21e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.04  E-value: 1.21e-03
                           10        20
                   ....*....|....*....|....*....
gi 594542479   325 YINRGDCFFQLGNLAFAEADYKQALALSP 353
Cdd:smart00028   4 LYNLGNAYLKLGDYDEALEYYEKALELDP 32
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
235-417 4.19e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.51  E-value: 4.19e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 235 IENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMvtdtqdnlvkqaQRQLLLTYNDFAVHCYNHGAYQEGVLLLNKA 314
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL------------DPDDAEALYNLGLAYLRLGRYEEALADYEQA 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 315 IRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSP 394
Cdd:COG0457   69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELG-------RYDEAIEAYERALELDP 141

                        170       180
                 ....*....|....*....|...
gi 594542479 395 QKPQYYLHRAKCRQFLQNTLGAR 417
Cdd:COG0457  142 DDADALYNLGIALEKLGRYEEAL 164
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 295-430 6.99e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 72.15  E-value: 6.99e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 295 AVHCYNHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqq 374
Cdd:COG4783   11 AQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG---- 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 594542479 375 khrQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLGARLDVATVLLLNPEY 430
Cdd:COG4783   87 ---DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
15-215 8.25e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.66  E-value: 8.25e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  15 PAKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAF 94
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  95 VLYLQGqclyelcDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNF- 173
Cdd:COG0457   85 ALQALG-------RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKl 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 594542479 174 --FQKAKLCYQDLRSALLLDPLHAQAKGLLQKMVDQAKQSLQDA 215
Cdd:COG0457  158 grYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLL 201
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 21-270 1.01e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 75.15  E-value: 1.01e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  21 YYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQG 100
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 101 qclyelcDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNFFQKAKLC 180
Cdd:COG2956   91 -------LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 181 YQDLRSALLLDPLHAQAKGLLqkmvdqakqslqdASTLAVQGKVHRALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDH 260
Cdd:COG2956  164 IEALEKALKLDPDCARALLLL-------------AELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEE 230

                        250
                 ....*....|
gi 594542479 261 AVEDFLKAMD 270
Cdd:COG2956  231 ALELLRKALE 240
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
215-404 1.01e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.66  E-value: 1.01e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 215 ASTLAVQGKVHRALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMvtdtqdnlvkqaQRQLLLTYNDF 294
Cdd:COG0457   15 GLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALEL------------DPDDAEALNNL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 295 AVHCYNHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGFCQQ 374
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEE 162

                        170       180       190
                 ....*....|....*....|....*....|
gi 594542479 375 KHRQFQTAEEHFSEAIRHSPQKPQYYLHRA 404
Cdd:COG0457  163 ALELLEKLEAAALAALLAAALGEAALALAA 192
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
290-431 1.20e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.27  E-value: 1.20e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 290 TYNDFAVHCYNHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKL 369
Cdd:COG0457   10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQAL 89

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 594542479 370 GfcqqkhrQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLGARLDVATVLLLNPEYP 431
Cdd:COG0457   90 G-------RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDA 144
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
45-295 1.01e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.58  E-value: 1.01e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  45 LHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcDFQEALCVFLQASDLQP 124
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLG-------RYEEALADYEQALELDP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 125 QNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSALLLDPLHAQAKGLLQKM 204
Cdd:COG0457   74 DDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIA 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 205 VDQAKQSLQDASTLAVQGKVHRALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMVTDTQDNLVKQAQ 284
Cdd:COG0457  154 LEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLAL 233

                        250
                 ....*....|.
gi 594542479 285 RQLLLTYNDFA 295
Cdd:COG0457  234 RLAALALYQYR 244
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 194-436 3.79e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.53  E-value: 3.79e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 194 HAQAKGLLQKMVDQAKQSLQDASTLAV----QGKVHRALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAM 269
Cdd:COG2956   24 PDKAIDLLEEALELDPETVEAHLALGNlyrrRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLL 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 270 DMVTDTQDnlvkqAQRQLLLTYNDfavhcynHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQAL 349
Cdd:COG2956  104 ELDPDDAE-----ALRLLAEIYEQ-------EGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAL 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 350 ALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLGARLDVATVLLLNPE 429
Cdd:COG2956  172 KLDPDCARALLLLAELYLEQG-------DYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS 244


                 ....*..
gi 594542479 430 YPKMAAV 436
Cdd:COG2956  245 DDLLLAL 251
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
21-202 5.15e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 69.65  E-value: 5.15e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  21 YYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQG 100
Cdd:COG0457   45 LYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELG 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 101 qclyelcDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNFFQKAKLC 180
Cdd:COG0457  125 -------RYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLL 197

                        170       180
                 ....*....|....*....|..
gi 594542479 181 YQDLRSALLLDPLHAQAKGLLQ 202
Cdd:COG0457  198 ALLLALEQALRKKLAILTLAAL 219
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 132-411 1.73e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 70.79  E-value: 1.73e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 132 RCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSALLLDPLHAQAKGLLQkmvDQAKQS 211
Cdd:COG3914    5 ALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALL---LLAALL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 212 LQDASTLAVQGKVHRALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMVTDtqdnlvkqaqrqLLLTY 291
Cdd:COG3914   82 ELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPD------------FAEAY 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 292 NDFAVHCYNHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGF 371
Cdd:COG3914  150 LNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACD 229

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 594542479 372 CQQKHRQFQTAEEHFSEAIRHSPQKPQYY------LHRAKCRQFLQ 411
Cdd:COG3914  230 WEVYDRFEELLAALARGPSELSPFALLYLpdddpaELLALARAWAQ 275
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
325-432 9.28e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.80  E-value: 9.28e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 325 YINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYYLHRA 404
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLG-------RYEEALADYEQALELDPDDAEALNNLG 83

                         90       100
                 ....*....|....*....|....*...
gi 594542479 405 KCRQFLQNTLGARLDVATVLLLNPEYPK 432
Cdd:COG0457   84 LALQALGRYEEALEDYDKALELDPDDAE 111
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 15-138 9.59e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 68.48  E-value: 9.59e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  15 PAKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAF 94
Cdd:COG3914  109 PDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGN 188

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 594542479  95 VLYLQGQclyelcdFQEALCVFLQASDLQPQNASFSYRCMACLL 138
Cdd:COG3914  189 ALQDLGR-------LEEAIAAYRRALELDPDNADAHSNLLFALR 225
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 207-353 9.66e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 63.29  E-value: 9.66e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 207 QAKQSLQDASTLAVQGKVHRALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMdmvtdtqdnlvkQAQRQ 286
Cdd:COG4783    3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEAL------------ELDPD 70

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 594542479 287 LLLTYNDFAVHCYNHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSP 353
Cdd:COG4783   71 EPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 16-156 3.30e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 61.75  E-value: 3.30e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  16 AKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFV 95
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 594542479  96 LYLQGqclyelcDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQ 156
Cdd:COG4783   82 LLKAG-------DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
121-367 1.26e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.33  E-value: 1.26e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 121 DLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSALLLDPLHAQAKGL 200
Cdd:COG0457    2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 201 LqkmvdqakqslqdASTLAVQGKVHRALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMVTDTQDNLV 280
Cdd:COG0457   82 L-------------GLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALY 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 281 KQAQRQLLLTYNDFAVHCYNHGAYQEGVLLLNKAiRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANL 360
Cdd:COG0457  149 NLGIALEKLGRYEEALELLEKLEAAALAALLAAA-LGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLAL 227


                 ....*..
gi 594542479 361 RMGVLQE 367
Cdd:COG0457  228 ALLLALR 234
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 16-400 1.61e-10

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 64.62  E-value: 1.61e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479   16 AKVREyynQGHQCLLQEDWEMSVLFFSRALHLDPKLVdFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFV 95
Cdd:TIGR00990 128 AKLKE---KGNKAYRNKDFNKAIKLYSKAIECKPDPV-YYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANA 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479   96 LYLQGQCLYELCDFQeALCVflqasdlqpqNASFSYRCMACLLA--LKRYHDCLALITREVKQGRASADVYIlrarlYNF 173
Cdd:TIGR00990 204 YDGLGKYADALLDLT-ASCI----------IDGFRNEQSAQAVErlLKKFAESKAKEILETKPENLPSVTFV-----GNY 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  174 FQ--KAKLCYQDLRSALLLDplHAQAKGLLQK----MVDQAKQSLQDASTLAVQgkvhralkcincAIENNPLDPNFFF- 246
Cdd:TIGR00990 268 LQsfRPKPRPAGLEDSNELD--EETGNGQLQLglksPESKADESYEEAARAFEK------------ALDLGKLGEKEAIa 333

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  247 --FRGTLRRRLQQFDHAVEDFLKAMDMVTDTQDNLVKQAQRQLLLTYNDFAvhcYNHgayqegvllLNKAIRDEQNEKGL 324
Cdd:TIGR00990 334 lnLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKA---EED---------FDKALKLNSEDPDI 401

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 594542479  325 YINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYY 400
Cdd:TIGR00990 402 YYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEG-------SIASSMATFRRCKKNFPEAPDVY 470
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 20-201 2.26e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.86  E-value: 2.26e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  20 EYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQ 99
Cdd:COG3914   46 LLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLAL 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 100 GQclyelcdFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLY---NFFQK 176
Cdd:COG3914  126 GR-------LEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALqdlGRLEE 198

                        170       180
                 ....*....|....*....|....*
gi 594542479 177 AKLCYqdlRSALLLDPLHAQAKGLL 201
Cdd:COG3914  199 AIAAY---RRALELDPDNADAHSNL 220
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
21-191 9.14e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 60.02  E-value: 9.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  21 YYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQG 100
Cdd:COG0457   79 LNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 101 qclyelcDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNFFQKAKLC 180
Cdd:COG0457  159 -------RYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLL 231

                        170
                 ....*....|.
gi 594542479 181 YQDLRSALLLD 191
Cdd:COG0457  232 ALRLAALALYQ 242
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
15-127 1.02e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 59.16  E-value: 1.02e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  15 PAKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNK-YLNRla 93
Cdd:COG4785   70 PDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYaYLNR-- 147

                         90       100       110
                 ....*....|....*....|....*....|....
gi 594542479  94 fvlylqGQCLYELCDFQEALCVFLQASDLQPQNA 127
Cdd:COG4785  148 ------GIALYYLGRYELAIADLEKALELDPNDP 175
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 29-188 1.17e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 60.13  E-value: 1.17e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  29 LLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcD 108
Cdd:COG2956  121 EQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQG-------D 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 109 FQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALItREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSAL 188
Cdd:COG2956  194 YEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELL-RKALELDPSDDLLLALADLLERKEGLEAALALLERQL 272
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
183-410 1.48e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 58.77  E-value: 1.48e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 183 DLRSALLLDPLHAQAKGLLQKMVDQAKQSLQDASTLAVQGKVHRALK-----CINCAIEN--------NPLDPNFFFFRG 249
Cdd:COG4785    1 LYALALALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALAlaaaaLAAAALAAeridralaLPDLAQLYYERG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 250 TLRRRLQQFDHAVEDFlkamdmvtdtqdnlvkqaqrqllltyndfavhcynhgayqegvlllNKAIRDEQNEKGLYINRG 329
Cdd:COG4785   81 VAYDSLGDYDLAIADF----------------------------------------------DQALELDPDLAEAYNNRG 114

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 330 DCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQF 409
Cdd:COG4785  115 LAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLG-------RYELAIADLEKALELDPNDPERALWLYLAERK 187


                 .
gi 594542479 410 L 410
Cdd:COG4785  188 L 188
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 58-192 1.66e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 56.74  E-value: 1.66e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  58 RAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcDFQEALCVFLQASDLQPQNASFSYRCMACL 137
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLG-------DLDEAIVLLHEALELDPDEPEARLNLGLAL 82

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 594542479 138 LALKRYHDCLALITREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSALLLDP 192
Cdd:COG4783   83 LKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 19-210 1.73e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.16  E-value: 1.73e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  19 REYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYL 98
Cdd:COG3914   79 ALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRR 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  99 QGQclyelcdFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITR--EVKQGRASADVYILRARL------ 170
Cdd:COG3914  159 LGR-------LEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRalELDPDNADAHSNLLFALRqacdwe 231

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 594542479 171 -YNFFQKAKLCYQDLRSALLLDPLHAQAKGLLQKMVDQAKQ 210
Cdd:COG3914  232 vYDRFEELLAALARGPSELSPFALLYLPDDDPAELLALARA 272
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 15-127 2.89e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.78  E-value: 2.89e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  15 PAKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAF 94
Cdd:COG4235   14 PNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGL 93

                         90       100       110
                 ....*....|....*....|....*....|...
gi 594542479  95 VLYLQGqclyelcDFQEALCVFLQASDLQPQNA 127
Cdd:COG4235   94 AAFQQG-------DYAEAIAAWQKLLALLPADA 119
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 43-170 3.31e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.78  E-value: 3.31e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  43 RALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcDFQEALCVFLQASDL 122
Cdd:COG4235    8 QALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAG-------DTEEAEELLERALAL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 594542479 123 QPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARL 170
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASI 128
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 29-124 4.82e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 55.74  E-value: 4.82e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  29 LLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcD 108
Cdd:COG5010   65 NKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLG-------Q 137

                         90
                 ....*....|....*.
gi 594542479 109 FQEALCVFLQASDLQP 124
Cdd:COG5010  138 DDEAKAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 303-428 7.86e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 55.35  E-value: 7.86e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 303 AYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTA 382
Cdd:COG5010   35 NNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSG-------DKDEA 107

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 594542479 383 EEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLGARLDVATVLLLNP 428
Cdd:COG5010  108 KEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 41-215 1.02e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.05  E-value: 1.02e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  41 FSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcDFQEALCVFLQAS 120
Cdd:COG2956   99 LEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQG-------DYDEAIEALEKAL 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 121 DLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSALLLDPLHAQAKGL 200
Cdd:COG2956  172 KLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLAL 251

                        170       180
                 ....*....|....*....|
gi 594542479 201 L-----QKMVDQAKQSLQDA 215
Cdd:COG2956  252 AdllerKEGLEAALALLERQ 271
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 15-156 3.00e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.89  E-value: 3.00e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  15 PAKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAf 94
Cdd:COG2956  141 PENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLA- 219

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 594542479  95 vlylqgQCLYELCDFQEALCVFLQASDLQPQNASFSYRCMAcLLALKRYHDCLALITREVKQ 156
Cdd:COG2956  220 ------ELYEKLGDPEEALELLRKALELDPSDDLLLALADL-LERKEGLEAALALLERQLRR 274
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 251-394 3.78e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 53.43  E-value: 3.78e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 251 LRRRLQQFDHAVEDFLKAMDMVTDTQDNLVKQAQRQLLLTYNDFAVHCYNHGAYQEGVLLLNKAIRDEQNEKGLYINRGD 330
Cdd:COG5010   17 LTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLAL 96

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 594542479 331 CFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSP 394
Cdd:COG5010   97 LYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLG-------QDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
331-429 8.90e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 50.55  E-value: 8.90e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 331 CFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEhFSEAIRHSPQKPQYYLHRAKCRQFL 410
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQG-------RYDEAIA-LEKALKLDPNNAEALLNLAELLLEL 72

                         90
                 ....*....|....*....
gi 594542479 411 QNTLGARLDVATVLLLNPE 429
Cdd:COG3063   73 GDYDEALAYLERALELDPS 91
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 226-356 1.35e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.16  E-value: 1.35e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 226 RALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMVTDTQDNLVKQAQRQllltyndfavhcYNHGAYQ 305
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEAL------------LAAGDTE 68

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 594542479 306 EGVLLLNKAIR-DEQNEKGLYiNRGDCFFQLGNLAFAEADYKQALALSPLDE 356
Cdd:COG4235   69 EAEELLERALAlDPDNPEALY-LLGLAAFQQGDYAEAIAAWQKLLALLPADA 119
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 24-268 1.55e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.09  E-value: 1.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479   24 QGHQCLLQEDWEMSVLFFSRALHLDPKLVdfYVFRAEAFIQLC--DFSSALQNLRRAYSYDPGNNKYLNrlafvlyLQGQ 101
Cdd:TIGR02917 131 RGLAYLGLGQLELAQKSYEQALAIDPRSL--YAKLGLAQLALAenRFDEARALIDEVLTADPGNVDALL-------LKGD 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  102 CLYELCDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYnfFQKAKlcY 181
Cdd:TIGR02917 202 LLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVD--FQKKN--Y 277

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  182 QDLRS----ALLLDP-----------------LHAQAKGLLQKMVDQAKQSLQD----ASTLAVQGKVHRALKCINCAIE 236
Cdd:TIGR02917 278 EDAREtlqdALKSAPeylpalllagaseyqlgNLEQAYQYLNQILKYAPNSHQArrllASIQLRLGRVDEAIATLSPALG 357

                         250       260       270
                  ....*....|....*....|....*....|..
gi 594542479  237 NNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKA 268
Cdd:TIGR02917 358 LDPDDPAALSLLGEAYLALGDFEKAAEYLAKA 389
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 248-431 2.00e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 54.61  E-value: 2.00e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 248 RGTLRRRLQQFDHAVEDFLKAMDMVTDTQDNLVKQAQRQLLLTYNDFAvHCYNHGAYQEGVLLLNKAIRDEQNEKglyin 327
Cdd:COG3914   14 AAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLA-LAAGEAAAAAAALLLLAALLELAALL----- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 328 rgdcFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYYLHRAKCR 407
Cdd:COG3914   88 ----LQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALG-------RLEEALAALRRALALNPDFAEAYLNLGEAL 156

                        170       180
                 ....*....|....*....|....
gi 594542479 408 QFLQNTLGARLDVATVLLLNPEYP 431
Cdd:COG3914  157 RRLGRLEEAIAALRRALELDPDNA 180
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 20-384 2.16e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 54.70  E-value: 2.16e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479   20 EYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQ 99
Cdd:TIGR02917  24 ELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQ 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  100 GQclyelcdFQEALCVFLQASDLQPQNAS--FSYRCMAcLLALKRYHDCLALITREVKQGRASADVYILRARL---YNFF 174
Cdd:TIGR02917 104 GK-------FQQVLDELPGKTLLDDEGAAelLALRGLA-YLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLalaENRF 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  175 QKAKlcyQDLRSALLLDPLHAQAKGLLqkmvdqakqslqdASTLAVQGKVHRALKCINCAIENNPLDPNFFFFRGTLRRR 254
Cdd:TIGR02917 176 DEAR---ALIDEVLTADPGNVDALLLK-------------GDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIE 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  255 LQQFDHAVEDFlkamdmvtdtqDNLVKQAQRQLLLTYNDFAVHcYNHGAYQEGVLLLNKAIR-DEQNEKGLYInRGDCFF 333
Cdd:TIGR02917 240 AGEFEEAEKHA-----------DALLKKAPNSPLAHYLKALVD-FQKKNYEDARETLQDALKsAPEYLPALLL-AGASEY 306

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|.
gi 594542479  334 QLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGFCQQKHRQFQTAEE 384
Cdd:TIGR02917 307 QLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALG 357
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
46-213 3.26e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 51.84  E-value: 3.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  46 HLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcDFQEALCVFLQASDLQPQ 125
Cdd:COG4785   67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLG-------DYDAALEDFDRALELDPD 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 126 NA-SFSYRCMAcLLALKRYHDCLALITREVKQGRASADVYILRarlynFFQKAKLCYQDLRSALLLDPL-HAQAKGLLQK 203
Cdd:COG4785  140 YAyAYLNRGIA-LYYLGRYELAIADLEKALELDPNDPERALWL-----YLAERKLDPEKALALLLEDWAtAYLLQGDTEE 213

                        170
                 ....*....|
gi 594542479 204 MVDQAKQSLQ 213
Cdd:COG4785  214 ARELFKLALA 223
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
29-124 4.04e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 48.63  E-value: 4.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  29 LLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQnLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcD 108
Cdd:COG3063    3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELG-------D 74

                         90
                 ....*....|....*.
gi 594542479 109 FQEALCVFLQASDLQP 124
Cdd:COG3063   75 YDEALAYLERALELDP 90
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 299-404 1.17e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.46  E-value: 1.17e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 299 YNHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQ 378
Cdd:COG4235   28 LRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQG-------D 100

                         90       100
                 ....*....|....*....|....*.
gi 594542479 379 FQTAEEHFSEAIRHSPQKPQYYLHRA 404
Cdd:COG4235  101 YAEAIAAWQKLLALLPADAPARLLEA 126
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 306-436 1.31e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.08  E-value: 1.31e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 306 EGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEH 385
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAG-------DTEEAEEL 73

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 594542479 386 FSEAIRHSPQKPQYYLHRAKCRQFLQNTLGARLDVATVLLLNPEYPKMAAV 436
Cdd:COG4235   74 LERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLL 124
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 21-126 2.23e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.88  E-value: 2.23e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  21 YYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQG 100
Cdd:COG4783   41 FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALG 120

                         90       100
                 ....*....|....*....|....*.
gi 594542479 101 QclyelcdFQEALCVFLQASDLQPQN 126
Cdd:COG4783  121 R-------PDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 15-131 2.25e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 51.15  E-value: 2.25e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  15 PAKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAF 94
Cdd:COG3914  143 PDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLF 222

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 594542479  95 VLYlqGQCLYELCDFQEALCVFLQASDLQPQNASFSY 131
Cdd:COG3914  223 ALR--QACDWEVYDRFEELLAALARGPSELSPFALLY 257
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 64-150 8.60e-06

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 44.55  E-value: 8.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479   64 QLCDFSSALQNLRRAYSYDPGNNKYLnrlafvlYLQGQCLYELCDFQEALCVfLQASDLQPQNASFSYRCMACLLALKRY 143
Cdd:pfam12895   1 DQHQYKNAIFLAERLLAAEPESPEDA-------YLLAQCLFLNGQYKRAYEL-LRKAKLNGSSLGCRYLFAQCLLKLKKY 72


                  ....*..
gi 594542479  144 HDCLALI 150
Cdd:pfam12895  73 DEALDAL 79
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 42-229 1.37e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 48.44  E-value: 1.37e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479   42 SRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKylnrlafVLYLQGQCLYELCDFQEALCVFLQASD 121
Cdd:TIGR00990 355 SKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPD-------IYYHRAQLHFIKGEFAQAGKDYQKSID 427

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  122 LQPQNAsFSYRCMACL-LALKRYHDCLALITREVKQGRASADVYILRARLY---NFFQKAKLCYqDLRSAL--LLDPLH- 194
Cdd:TIGR00990 428 LDPDFI-FSHIQLGVTqYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLldqNKFDEAIEKF-DTAIELekETKPMYm 505

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  195 -------------------AQAKGLLQKMV------DQAKQSLqdASTLAVQGKVHRALK 229
Cdd:TIGR00990 506 nvlplinkalalfqwkqdfIEAENLCEKALiidpecDIAVATM--AQLLLQQGDVDEALK 563
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 24-129 2.86e-05

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 47.09  E-value: 2.86e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  24 QGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNK-YLNrlafvlylQGQC 102
Cdd:PLN03088   8 KAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKaYLR--------KGTA 79

                         90       100
                 ....*....|....*....|....*..
gi 594542479 103 LYELCDFQEALCVFLQASDLQPQNASF 129
Cdd:PLN03088  80 CMKLEEYQTAKAALEKGASLAPGDSRF 106
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 147-283 3.05e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 44.23  E-value: 3.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 147 LALITREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSALLLDPLHAQAKGLLqkmvdqakqslqdASTLAVQGKVHR 226
Cdd:COG4235    3 IARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDL-------------AEALLAAGDTEE 69

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 594542479 227 ALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMV-TDTQDNLVKQA 283
Cdd:COG4235   70 AEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLpADAPARLLEAS 127
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
302-394 6.98e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.08  E-value: 6.98e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 302 GAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEAdYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQT 381
Cdd:COG3063    6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELG-------DYDE 77

                         90
                 ....*....|...
gi 594542479 382 AEEHFSEAIRHSP 394
Cdd:COG3063   78 ALAYLERALELDP 90
TPR_1 pfam00515
Tetratricopeptide repeat;
325-353 1.32e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 39.71  E-value: 1.32e-04
                          10        20
                  ....*....|....*....|....*....
gi 594542479  325 YINRGDCFFQLGNLAFAEADYKQALALSP 353
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNP 32
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 41-193 1.37e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.03  E-value: 1.37e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  41 FSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGQCLYELCDFQEALCVFLQAS 120
Cdd:COG5010    2 RALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQAL 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 594542479 121 DLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSALLLDPL 193
Cdd:COG5010   82 QLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPL 154
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 247-354 1.59e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.64  E-value: 1.59e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 247 FRGTLRRRLQQFDHAVEDFLKAMDMVTDTQDnlvkqaqrqlllTYNDFAVHCYNHGAYQEGVLLLNKAIRDEQNEKGLYI 326
Cdd:COG5010   59 PSDNLYNKLGDFEESLALLEQALQLDPNNPE------------LYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYS 126

                         90       100
                 ....*....|....*....|....*...
gi 594542479 327 NRGDCFFQLGNLAFAEADYKQALALSPL 354
Cdd:COG5010  127 NLAALLLSLGQDDEAKAALQRALGTSPL 154
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 91-269 2.01e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.10  E-value: 2.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  91 RLAFVLYLQGQCLYELCDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYhdclalitrevkqgrasadvyilrarl 170
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDL--------------------------- 54

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 171 ynffQKAklcYQDLRSALLLDPLHAQAKGLLqkmvdqakqslqdASTLAVQGKVHRALKCINCAIENNPLDPNFFFFRGT 250
Cdd:COG4783   55 ----DEA---IVLLHEALELDPDEPEARLNL-------------GLALLKAGDYDEALALLEKALKLDPEHPEAYLRLAR 114

                        170
                 ....*....|....*....
gi 594542479 251 LRRRLQQFDHAVEDFLKAM 269
Cdd:COG4783  115 AYRALGRPDEAIAALEKAL 133
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
251-353 4.16e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.15  E-value: 4.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 251 LRRRLQQFDHAVEDFLKAMdmvtdtqdnlvkQAQRQLLLTYNDFAVHCYNHGAYQEGvLLLNKAIRDEQNEKGLYINRGD 330
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKAL------------ELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAE 67

                         90       100
                 ....*....|....*....|...
gi 594542479 331 CFFQLGNLAFAEADYKQALALSP 353
Cdd:COG3063   68 LLLELGDYDEALAYLERALELDP 90
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 310-399 4.70e-04

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 43.24  E-value: 4.70e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 310 LLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEA 389
Cdd:PLN03088  24 LYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLE-------EYQTAKAALEKG 96

                         90
                 ....*....|
gi 594542479 390 IRHSPQKPQY 399
Cdd:PLN03088  97 ASLAPGDSRF 106
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
61-152 4.77e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.77  E-value: 4.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  61 AFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcDFQEALcVFLQASDLQPQNASFSYRCMACLLAL 140
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQG-------RYDEAI-ALEKALKLDPNNAEALLNLAELLLEL 72

                         90
                 ....*....|..
gi 594542479 141 KRYHDCLALITR 152
Cdd:COG3063   73 GDYDEALAYLER 84
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
337-512 4.93e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.21  E-value: 4.93e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 337 NLAFAEADYKQALALSPLDEGANLRM-GVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLG 415
Cdd:COG4785   53 LAAAALAAERIDRALALPDLAQLYYErGVAYDSLG-------DYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDA 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 416 ARLDVATVLLLNPEYPkmAAVMN---TLFpsmtvenvlKSQVAELAKLQLSRMIENGPKNiyPQSTVVQRLLERRKA--- 489
Cdd:COG4785  126 ALEDFDRALELDPDYA--YAYLNrgiALY---------YLGRYELAIADLEKALELDPND--PERALWLYLAERKLDpek 192

                        170       180
                 ....*....|....*....|....*..
gi 594542479 490 --QVLVKLWK--QERLGTPEEEVTLYQ 512
Cdd:COG4785  193 alALLLEDWAtaYLLQGDTEEARELFK 219
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 58-124 5.47e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 42.62  E-value: 5.47e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 594542479  58 RAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLafvlylqGQCLYELCDFQEALCVFLQASDLQP 124
Cdd:cd24142    6 KAEELLDQGNFELALKFLQRALELEPNNVEALELL-------GEILLELGDVEEAREVLLRAIELDP 65
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 20-113 6.36e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 42.62  E-value: 6.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  20 EYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNN--KYlnrlafvLY 97
Cdd:cd24142    2 ELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGyeKY-------LY 74

                         90
                 ....*....|....*.
gi 594542479  98 LqGQclyeLCDFQEAL 113
Cdd:cd24142   75 L-GQ----LSGGEEAL 85
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 31-417 6.54e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.15  E-value: 6.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479   31 QEDWEMSVLFFSRALHLDPKLVdfYVFRAEAFIQLC--DFSSALQNLRRAYSYDPGNNKYLNrlafvlyLQGQCLYELCD 108
Cdd:TIGR02917 308 LGNLEQAYQYLNQILKYAPNSH--QARRLLASIQLRlgRVDEAIATLSPALGLDPDDPAALS-------LLGEAYLALGD 378

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  109 FQEALCVFLQASDLQPQNASFSYRcmaclLALKRyhdclaLITREVKQGRAsadvyilrarlyNFFQKAKLCYQDLRSAL 188
Cdd:TIGR02917 379 FEKAAEYLAKATELDPENAAARTQ-----LGISK------LSQGDPSEAIA------------DLETAAQLDPELGRADL 435

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  189 LL----------DPLHAQAKGLLQKMVDQAKQSLQDASTLAVQGKVHRALKCINCAIEnnpLDPNFFFFRGTLRRRLQQF 258
Cdd:TIGR02917 436 LLilsylrsgqfDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALS---IEPDFFPAAANLARIDIQE 512

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  259 DHAVEDFLKAMDMVTDTQDNLvkqaqrQLLLTYNDFAVHcynHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNL 338
Cdd:TIGR02917 513 GNPDDAIQRFEKVLTIDPKNL------RAILALAGLYLR---TGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQL 583

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 594542479  339 AFAEADYKQALALSPlDEGANLRMgvlqekLGFCQQKHRQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLGAR 417
Cdd:TIGR02917 584 KKALAILNEAADAAP-DSPEAWLM------LGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAI 655
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
70-236 7.44e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 41.82  E-value: 7.44e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  70 SALQNLRRAYSYDPGNNKYLNRLAFVLYLQGQCLYELCDFQEALCVFLQASDLQPQNAS-FSYRCMAcLLALKRYHDCLA 148
Cdd:COG4785   50 AAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEaYNNRGLA-YLLLGDYDAALE 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 149 LITREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSALLLDPLHAQA---KGLLQKMVD--QAKQSLQD--ASTLAVQ 221
Cdd:COG4785  129 DFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERalwLYLAERKLDpeKALALLLEdwATAYLLQ 208

                        170
                 ....*....|....*
gi 594542479 222 GKVHRALKCINCAIE 236
Cdd:COG4785  209 GDTEEARELFKLALA 223
TPR_11 pfam13414
TPR repeat;
329-370 9.13e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 37.45  E-value: 9.13e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 594542479  329 GDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLG 370
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 29-350 9.43e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 9.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479   29 LLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcD 108
Cdd:TIGR02917 408 LSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKG-------D 480

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  109 FQEALCVFLQASDLQPQN--ASFSYRCMA-----CLLALKRYHDCLALITREVKQGRASADVYILRAR---LYNFFQKA- 177
Cdd:TIGR02917 481 LAKAREAFEKALSIEPDFfpAAANLARIDiqegnPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNeeeAVAWLEKAa 560

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  178 KLCYQDLRSALLLDPLH------AQAKGLLQKMVDQAKQSLQD----ASTLAVQGKVHRALKCINCAIENNPLDPNFFFF 247
Cdd:TIGR02917 561 ELNPQEIEPALALAQYYlgkgqlKKALAILNEAADAAPDSPEAwlmlGRAQLAAGDLNKAVSSFKKLLALQPDSALALLL 640

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  248 RGTLRRRLQQFDHAVEDFLKAMDMVTDTQDnlVKQAQRQLLLTYNDFavhcynhgayqegvlllNKAIRDEQNEKGLYIN 327
Cdd:TIGR02917 641 LADAYAVMKNYAKAITSLKRALELKPDNTE--AQIGLAQLLLAAKRT-----------------ESAKKIAKSLQKQHPK 701

                         330       340
                  ....*....|....*....|...
gi 594542479  328 RGDCFFQLGNLAFAEADYKQALA 350
Cdd:TIGR02917 702 AALGFELEGDLYLRQKDYPAAIQ 724
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 325-353 1.21e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.04  E-value: 1.21e-03
                           10        20
                   ....*....|....*....|....*....
gi 594542479   325 YINRGDCFFQLGNLAFAEADYKQALALSP 353
Cdd:smart00028   4 LYNLGNAYLKLGDYDEALEYYEKALELDP 32
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 71-208 1.79e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.22  E-value: 1.79e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479  71 ALQNLRRAYSYDPGNnkylnrlAFVLYLQGQCLYELCDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALI 150
Cdd:COG4235    2 AIARLRQALAANPND-------AEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELL 74

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 594542479 151 TREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSALLLDPLHAQAKgLLQKMVDQA 208
Cdd:COG4235   75 ERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPAR-LLEASIAEA 131
TPR_12 pfam13424
Tetratricopeptide repeat;
324-391 2.87e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 36.98  E-value: 2.87e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 594542479  324 LYINRGDCFFQLGNLAFAEADYKQALAL-SPLDEGANLRMGVLQEKLGFCQQKHRQFQTAEEHFSEAIR 391
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIaRRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALA 73
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 324-353 3.48e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 35.58  E-value: 3.48e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 594542479  324 LYINRGDCFFQLGNLAFAEADYKQALALSP 353
Cdd:pfam07719   3 ALYNLGLAYYKLGDYEEALEAYEKALELDP 32
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 299-398 7.49e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 36.89  E-value: 7.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 594542479 299 YNHGAYQEGVLLLNKAIRDEQNEKGL---YINRGDCFFQLGNLAFAEADYKQALAL---SPLDEGANLRMGVLQEKLGfc 372
Cdd:COG1729    4 LKAGDYDEAIAAFKAFLKRYPNSPLApdaLYWLGEAYYALGDYDEAAEAFEKLLKRypdSPKAPDALLKLGLSYLELG-- 81

                         90       100
                 ....*....|....*....|....*.
gi 594542479 373 qqkhrQFQTAEEHFSEAIRHSPQKPQ 398
Cdd:COG1729   82 -----DYDKARATLEELIKKYPDSEA 102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH