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Conserved domains on  [gi|585866234|ref|NP_001276949|]
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outer dynein arm-docking complex subunit 2 isoform 1 [Homo sapiens]

Protein Classification

HEAT repeat domain-containing protein( domain architecture ID 11444215)

HEAT repeat domain-containing protein similar to Homo sapiens deoxyhypusine hydroxylase (DOHH), which catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor

CATH:  1.25.10.10
Gene Ontology:  GO:0005515
PubMed:  10378263
SCOP:  4001283

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
854-1032 2.72e-09

HEAT repeat [General function prediction only];


:

Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 56.56  E-value: 2.72e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  854 VKASAAWALCpcIKNAKDAgemvrsfvggLELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDHGVVPLLSKLANT 933
Cdd:COG1413     1 VRRAAARALG--RLGDPAA----------VPALIAALADEDPDVRAAAARA----------LGRLGDPRAVPALLEALKD 58

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  934 NNNKLRHHLAEAISRccmwgrnrvaFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDAdncitmhengAVKLLLDMV 1013
Cdd:COG1413    59 PDPEVRAAAAEALGR----------IGDPEAVPALIAALKDEDPEVRRAAAEALGRLGDPA----------AVPALLEAL 118

                         170
                  ....*....|....*....
gi 585866234 1014 GSPDQDLQEAAAGCISNIR 1032
Cdd:COG1413   119 KDPDWEVRRAAARALGRLG 137
HEAT COG1413
HEAT repeat [General function prediction only];
627-782 8.62e-06

HEAT repeat [General function prediction only];


:

Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 46.55  E-value: 8.62e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  627 AIRKAGGIPLLARLLKTSHENMLIPVVGTLqecaseenyrAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKet 706
Cdd:COG1413    11 RLGDPAAVPALIAALADEDPDVRAAAARAL----------GRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPE-- 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 585866234  707 rdlvrlhgGLKPLASLLNNTDNKERLAAVTGaiwkcsiskenVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGE 782
Cdd:COG1413    79 --------AVPALIAALKDEDPEVRRAAAEA-----------LGRLGDPAAVPALLEALKDPDWEVRRAAARALGR 135
PLN03200 super family cl33659
cellulose synthase-interactive protein; Provisional
 449-684 1.14e-03

cellulose synthase-interactive protein; Provisional


The actual alignment was detected with superfamily member PLN03200:

Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 43.17  E-value: 1.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  449 SEYWQ---IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEvkCKIGSLKILKEISHNP 525
Cdd:PLN03200 1644 SEYYFevpVAVLVKLLRSTSESTVVVALNALLVLERDDSSSAEQMAESGAIEALLELLRSHQ--CEEAAARLLEALFNNV 1721

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  526 QIRQ-NIVDLGGLPIMVNILDsPH---KSLKCLAAETIANVAkfkrarrvvrQHGGITKlvalldcAHDSTKP--AQSSL 599
Cdd:PLN03200 1722 KVREmKATKYAIAPLSQYLLD-PQtrsQQARLLAALALGDLF----------QHEGLAR-------STDAVSAcrALVSL 1783

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  600 YEARDVE----VARCGALALWSCSKshTNKEAIRKAGGIPLLARLLKTSHEN------MLIPVV---GTLQECASEENYR 666
Cdd:PLN03200 1784 LEDQPTEemkmVAICALQNLVMHSR--TNKRAVAEAGGVQVVQELLLSSNPDtsgqaaLLIKLLfsnHTIQEYASSELIR 1861

                         250       260
                  ....*....|....*....|....*.
gi 585866234  667 ---AAIKAE-----RIIENLVKNLNS 684
Cdd:PLN03200 1862 altAALEKDlwstaTVNEEVLRALNV 1887
 
Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
854-1032 2.72e-09

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 56.56  E-value: 2.72e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  854 VKASAAWALCpcIKNAKDAgemvrsfvggLELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDHGVVPLLSKLANT 933
Cdd:COG1413     1 VRRAAARALG--RLGDPAA----------VPALIAALADEDPDVRAAAARA----------LGRLGDPRAVPALLEALKD 58

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  934 NNNKLRHHLAEAISRccmwgrnrvaFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDAdncitmhengAVKLLLDMV 1013
Cdd:COG1413    59 PDPEVRAAAAEALGR----------IGDPEAVPALIAALKDEDPEVRRAAAEALGRLGDPA----------AVPALLEAL 118

                         170
                  ....*....|....*....
gi 585866234 1014 GSPDQDLQEAAAGCISNIR 1032
Cdd:COG1413   119 KDPDWEVRRAAARALGRLG 137
HEAT COG1413
HEAT repeat [General function prediction only];
627-782 8.62e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 46.55  E-value: 8.62e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  627 AIRKAGGIPLLARLLKTSHENMLIPVVGTLqecaseenyrAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKet 706
Cdd:COG1413    11 RLGDPAAVPALIAALADEDPDVRAAAARAL----------GRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPE-- 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 585866234  707 rdlvrlhgGLKPLASLLNNTDNKERLAAVTGaiwkcsiskenVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGE 782
Cdd:COG1413    79 --------AVPALIAALKDEDPEVRRAAAEA-----------LGRLGDPAAVPALLEALKDPDWEVRRAAARALGR 135
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 842-947 3.03e-04

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 40.78  E-value: 3.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234   842 LLWSLLKNPHPDVKASAAWALCPCikNAKDAgemvrsfvggLELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDH 921
Cdd:pfam13646    4 LLQALLRDPDPEVRAAAIRALGRI--GDPEA----------VPALLELLKDEDPAVRRAAAEA----------LGKIGDP 61

                           90       100
                   ....*....|....*....|....*..
gi 585866234   922 GVVPLLSKLANTNNNK-LRHHLAEAIS 947
Cdd:pfam13646   62 EALPALLELLRDDDDDvVRAAAAEALA 88
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 624-661 7.37e-04

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 38.20  E-value: 7.37e-04
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 585866234   624 NKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECAS 661
Cdd:pfam00514    4 NKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 625-862 7.90e-04

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 43.55  E-value: 7.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  625 KEAIRKAGGIPLLARLLKT----SHENMLIpVVGTLqeCASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQC 700
Cdd:PLN03200  481 KWAITAAGGIPPLVQLLETgsqkAKEDSAT-VLWNL--CCHSEDIRACVESAGAVPALLWLLKNGGPKGQEIAAKTLTKL 557

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  701 AEDKETRDLVRLhgglkpLASLLNNT-DNKERLAAVTGAIWkCSISKENVtkFRE----YKAIETLVGLLTDQPEEVLVN 775
Cdd:PLN03200  558 VRTADAATISQL------TALLLGDLpESKVHVLDVLGHVL-SVASLEDL--VREgsaaNDALRTLIQLLSSSKEETQEK 628

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  776 VVGALGECCQERENrvivrKCGG------IQPLVNLLVGINQALLVNVTKAVGA---CAVEPESMMIIDRlDGVRLLWSL 846
Cdd:PLN03200  629 AASVLADIFSSRQD-----LCESlatdeiINPCIKLLTNNTEAVATQSARALAAlsrSIKENRKVSYAAE-DAIKPLIKL 702

                         250
                  ....*....|....*.
gi 585866234  847 LKNPHPDVKASAAWAL 862
Cdd:PLN03200  703 AKSSSIEVAEQAVCAL 718
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 449-684 1.14e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 43.17  E-value: 1.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  449 SEYWQ---IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEvkCKIGSLKILKEISHNP 525
Cdd:PLN03200 1644 SEYYFevpVAVLVKLLRSTSESTVVVALNALLVLERDDSSSAEQMAESGAIEALLELLRSHQ--CEEAAARLLEALFNNV 1721

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  526 QIRQ-NIVDLGGLPIMVNILDsPH---KSLKCLAAETIANVAkfkrarrvvrQHGGITKlvalldcAHDSTKP--AQSSL 599
Cdd:PLN03200 1722 KVREmKATKYAIAPLSQYLLD-PQtrsQQARLLAALALGDLF----------QHEGLAR-------STDAVSAcrALVSL 1783

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  600 YEARDVE----VARCGALALWSCSKshTNKEAIRKAGGIPLLARLLKTSHEN------MLIPVV---GTLQECASEENYR 666
Cdd:PLN03200 1784 LEDQPTEemkmVAICALQNLVMHSR--TNKRAVAEAGGVQVVQELLLSSNPDtsgqaaLLIKLLfsnHTIQEYASSELIR 1861

                         250       260
                  ....*....|....*....|....*.
gi 585866234  667 ---AAIKAE-----RIIENLVKNLNS 684
Cdd:PLN03200 1862 altAALEKDlwstaTVNEEVLRALNV 1887
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 524-563 2.20e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 36.66  E-value: 2.20e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 585866234   524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA 563
Cdd:pfam00514    1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 621-656 2.67e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 36.64  E-value: 2.67e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 585866234    621 SHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTL 656
Cdd:smart00185    1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWAL 36
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 881-910 9.15e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.10  E-value: 9.15e-03
                            10        20        30
                    ....*....|....*....|....*....|
gi 585866234    881 GGLELIVNLLKSDNKEVLASVCAAITNIAK 910
Cdd:smart00185   12 GGLPALVELLKSEDEEVVKEAAWALSNLSS 41
 
Name Accession Description Interval E-value
HEAT COG1413
HEAT repeat [General function prediction only];
854-1032 2.72e-09

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 56.56  E-value: 2.72e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  854 VKASAAWALCpcIKNAKDAgemvrsfvggLELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDHGVVPLLSKLANT 933
Cdd:COG1413     1 VRRAAARALG--RLGDPAA----------VPALIAALADEDPDVRAAAARA----------LGRLGDPRAVPALLEALKD 58

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  934 NNNKLRHHLAEAISRccmwgrnrvaFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDAdncitmhengAVKLLLDMV 1013
Cdd:COG1413    59 PDPEVRAAAAEALGR----------IGDPEAVPALIAALKDEDPEVRRAAAEALGRLGDPA----------AVPALLEAL 118

                         170
                  ....*....|....*....
gi 585866234 1014 GSPDQDLQEAAAGCISNIR 1032
Cdd:COG1413   119 KDPDWEVRRAAARALGRLG 137
HEAT COG1413
HEAT repeat [General function prediction only];
840-990 1.40e-07

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 51.55  E-value: 1.40e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  840 VRLLWSLLKNPHPDVKASAAWALcpciknakdaGEMVRSfvGGLELIVNLLKSDNKEVLASVCAAITNIAKDQenlavit 919
Cdd:COG1413    18 VPALIAALADEDPDVRAAAARAL----------GRLGDP--RAVPALLEALKDPDPEVRAAAAEALGRIGDPE------- 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 585866234  920 dhgVVPLLSKLANTNNNKLRHHLAEAISRccmwgrnrvaFGEHKAVAPLVRYLKSNDTNVHRATAQALYQL 990
Cdd:COG1413    79 ---AVPALIAALKDEDPEVRRAAAEALGR----------LGDPAAVPALLEALKDPDWEVRRAAARALGRL 136
HEAT COG1413
HEAT repeat [General function prediction only];
627-782 8.62e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 46.55  E-value: 8.62e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  627 AIRKAGGIPLLARLLKTSHENMLIPVVGTLqecaseenyrAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDKet 706
Cdd:COG1413    11 RLGDPAAVPALIAALADEDPDVRAAAARAL----------GRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPE-- 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 585866234  707 rdlvrlhgGLKPLASLLNNTDNKERLAAVTGaiwkcsiskenVTKFREYKAIETLVGLLTDQPEEVLVNVVGALGE 782
Cdd:COG1413    79 --------AVPALIAALKDEDPEVRRAAAEA-----------LGRLGDPAAVPALLEALKDPDWEVRRAAARALGR 135
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 842-947 3.03e-04

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 40.78  E-value: 3.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234   842 LLWSLLKNPHPDVKASAAWALCPCikNAKDAgemvrsfvggLELIVNLLKSDNKEVLASVCAAitniakdqenLAVITDH 921
Cdd:pfam13646    4 LLQALLRDPDPEVRAAAIRALGRI--GDPEA----------VPALLELLKDEDPAVRRAAAEA----------LGKIGDP 61

                           90       100
                   ....*....|....*....|....*..
gi 585866234   922 GVVPLLSKLANTNNNK-LRHHLAEAIS 947
Cdd:pfam13646   62 EALPALLELLRDDDDDvVRAAAAEALA 88
HEAT COG1413
HEAT repeat [General function prediction only];
756-948 5.44e-04

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 41.15  E-value: 5.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  756 KAIETLVGLLTDQPEEVLVNVVGALGECCQERenrvivrkcggiqplvnllvginqallvnvtkavgacAVEPesmmiid 835
Cdd:COG1413    16 AAVPALIAALADEDPDVRAAAARALGRLGDPR-------------------------------------AVPA------- 51

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  836 rldgvrlLWSLLKNPHPDVKASAAWALCpCIKNAKdagemvrsfvgGLELIVNLLKSDNKEVLASVCAAitniakdqenL 915
Cdd:COG1413    52 -------LLEALKDPDPEVRAAAAEALG-RIGDPE-----------AVPALIAALKDEDPEVRRAAAEA----------L 102

                         170       180       190
                  ....*....|....*....|....*....|...
gi 585866234  916 AVITDHGVVPLLSKLANTNNNKLRHHLAEAISR 948
Cdd:COG1413   103 GRLGDPAAVPALLEALKDPDWEVRRAAARALGR 135
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 624-661 7.37e-04

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 38.20  E-value: 7.37e-04
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 585866234   624 NKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECAS 661
Cdd:pfam00514    4 NKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 625-862 7.90e-04

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 43.55  E-value: 7.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  625 KEAIRKAGGIPLLARLLKT----SHENMLIpVVGTLqeCASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQC 700
Cdd:PLN03200  481 KWAITAAGGIPPLVQLLETgsqkAKEDSAT-VLWNL--CCHSEDIRACVESAGAVPALLWLLKNGGPKGQEIAAKTLTKL 557

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  701 AEDKETRDLVRLhgglkpLASLLNNT-DNKERLAAVTGAIWkCSISKENVtkFRE----YKAIETLVGLLTDQPEEVLVN 775
Cdd:PLN03200  558 VRTADAATISQL------TALLLGDLpESKVHVLDVLGHVL-SVASLEDL--VREgsaaNDALRTLIQLLSSSKEETQEK 628

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  776 VVGALGECCQERENrvivrKCGG------IQPLVNLLVGINQALLVNVTKAVGA---CAVEPESMMIIDRlDGVRLLWSL 846
Cdd:PLN03200  629 AASVLADIFSSRQD-----LCESlatdeiINPCIKLLTNNTEAVATQSARALAAlsrSIKENRKVSYAAE-DAIKPLIKL 702

                         250
                  ....*....|....*.
gi 585866234  847 LKNPHPDVKASAAWAL 862
Cdd:PLN03200  703 AKSSSIEVAEQAVCAL 718
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 449-684 1.14e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 43.17  E-value: 1.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  449 SEYWQ---IQKLVKYLKGGNQTATVIALCSMRDFSLAQETCQLAIRDVGGLEVLINLLETDEvkCKIGSLKILKEISHNP 525
Cdd:PLN03200 1644 SEYYFevpVAVLVKLLRSTSESTVVVALNALLVLERDDSSSAEQMAESGAIEALLELLRSHQ--CEEAAARLLEALFNNV 1721

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  526 QIRQ-NIVDLGGLPIMVNILDsPH---KSLKCLAAETIANVAkfkrarrvvrQHGGITKlvalldcAHDSTKP--AQSSL 599
Cdd:PLN03200 1722 KVREmKATKYAIAPLSQYLLD-PQtrsQQARLLAALALGDLF----------QHEGLAR-------STDAVSAcrALVSL 1783

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234  600 YEARDVE----VARCGALALWSCSKshTNKEAIRKAGGIPLLARLLKTSHEN------MLIPVV---GTLQECASEENYR 666
Cdd:PLN03200 1784 LEDQPTEemkmVAICALQNLVMHSR--TNKRAVAEAGGVQVVQELLLSSNPDtsgqaaLLIKLLfsnHTIQEYASSELIR 1861

                         250       260
                  ....*....|....*....|....*.
gi 585866234  667 ---AAIKAE-----RIIENLVKNLNS 684
Cdd:PLN03200 1862 altAALEKDlwstaTVNEEVLRALNV 1887
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 923-1025 1.23e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 38.86  E-value: 1.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234   923 VVPLLSKLANTNNNKLRHHLAEAISRccmwgrnrvaFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDAdncitmhe 1002
Cdd:pfam13646    1 LPALLQALLRDPDPEVRAAAIRALGR----------IGDPEAVPALLELLKDEDPAVRRAAAEALGKIGDPE-------- 62

                           90       100
                   ....*....|....*....|....
gi 585866234  1003 ngAVKLLLDMVGS-PDQDLQEAAA 1025
Cdd:pfam13646   63 --ALPALLELLRDdDDDVVRAAAA 84
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 1002-1031 1.23e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 37.43  E-value: 1.23e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 585866234  1002 ENGAVKLLLDMVGSPDQDLQEAAAGCISNI 1031
Cdd:pfam00514   10 EAGAVPPLVRLLSSPDEEVQEEAAWALSNL 39
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 524-563 2.20e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 36.66  E-value: 2.20e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 585866234   524 NPQIRQNIVDLGGLPIMVNILDSPHKSLKCLAAETIANVA 563
Cdd:pfam00514    1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 621-656 2.67e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 36.64  E-value: 2.67e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 585866234    621 SHTNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTL 656
Cdd:smart00185    1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWAL 36
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 885-987 3.17e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 37.70  E-value: 3.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585866234   885 LIVNLLKSDNKEVLASVCAAITNIaKDQEnlavitdhgVVPLLSKLANTNNNKLRHHLAEAISRccmwgrnrvaFGEHKA 964
Cdd:pfam13646    4 LLQALLRDPDPEVRAAAIRALGRI-GDPE---------AVPALLELLKDEDPAVRRAAAEALGK----------IGDPEA 63

                           90       100
                   ....*....|....*....|....
gi 585866234   965 VAPLVRYLKS-NDTNVHRATAQAL 987
Cdd:pfam13646   64 LPALLELLRDdDDDVVRAAAAEAL 87
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 881-910 9.15e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.10  E-value: 9.15e-03
                            10        20        30
                    ....*....|....*....|....*....|
gi 585866234    881 GGLELIVNLLKSDNKEVLASVCAAITNIAK 910
Cdd:smart00185   12 GGLPALVELLKSEDEEVVKEAAWALSNLSS 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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