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Conserved domains on  [gi|554506543|ref|NP_001273009|]
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ninein isoform 3 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
665-1322 4.10e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.44  E-value: 4.10e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  665 LEKRVSELRSEIADLEGQAAVLREAhhkascrheeekRQLQmafdEEKAQLQEELRQEHERELQARLQQAAESFRQEREG 744
Cdd:COG1196   191 LEDILGELERQLEPLERQAEKAERY------------RELK----EELKELEAELLLLKLRELEAELEELEAELEELEAE 254
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  745 LAQAawtEEKVRGLEQSYQEQLLSLEEKhalekeelreelsehhRRELQEGREEmETECNRRVSQIEAQCQADCEKvteh 824
Cdd:COG1196   255 LEEL---EAELAELEAELEELRLELEEL----------------ELELEEAQAE-EYELLAELARLEQDIARLEER---- 310
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  825 ceqtlqslevrhRQELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRERATAAAMKQEQEILERTYKDRLNIL 904
Cdd:COG1196   311 ------------RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  905 STERKQLLQDLKDLQNASESQHgllsgQILELKRSQERELRDQGQALcQTGVSEQLASQQLERLRVEHEQERREMTGKLA 984
Cdd:COG1196   379 EELEELAEELLEALRAAAELAA-----QLEELEEAEEALLERLERLE-EELEELEEALAELEEEEEEEEEALEEAAEEEA 452
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  985 ALESAHRASLERADQEKAEMSTEICRLQNTVKDMQQAASLLMLQGGCQATAGEEAEGDGAMSLLQQGEQLLEEnGDVLIS 1064
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGA-VAVLIG 531
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1065 LQRAHEHAVKenakmATEISRLQQRLKKLEpgSVISSCLEEGTSEISGSSREQVEPIMKQGPATKHFLSDLGDHEARDLA 1144
Cdd:COG1196   532 VEAAYEAALE-----AALAAALQNIVVEDD--EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV 604
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1145 StgTSSVQRQECKTEASEASLDCFSELENSEDTRTESWDLKSQISQLREQLTVLRADCDRASERKQDLLFDISVLKKKLK 1224
Cdd:COG1196   605 A--SDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE 682
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1225 MLERlpEASSRYKVLYEDAARENSCLQEELRLVETRYEESLDSNKELTAEVYRLQDEMKKMEEVMETFLSLEKSYDEVKV 1304
Cdd:COG1196   683 ELAE--RLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP 760
                         650
                  ....*....|....*...
gi 554506543 1305 ENEELRALVLRLQGKMEK 1322
Cdd:COG1196   761 DLEELERELERLEREIEA 778
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
344-921 1.84e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.13  E-value: 1.84e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  344 LALENELLVTKNGIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRN--EYNLRK 421
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQaeEYELLA 295
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  422 LDEEYKERIAALKnELRQEREQMLQQVGKQRVELEQEIQKAKTEENYIRDRLALSLKENNRLETELLENAEKLAEYESLT 501
Cdd:COG1196   296 ELARLEQDIARLE-ERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  502 QKLQRSLENVLAEKFGDLDpSSAEFFLQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPLKNSLSEELd 581
Cdd:COG1196   375 AEAEEELEELAEELLEALR-AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA- 452
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  582 ghsggiepdqgpgsEECNPLNMSIEAELVIEQMKEQHHRDLCHLRLELEDKVRHYEKQLDDTRVASEQEQAAMKQKYEQG 661
Cdd:COG1196   453 --------------ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  662 VHTLEKRVSELRSEIADLEGQAAVLREAHHKASCRHEEEKRQLQMAFDEEKAQLQEELRQEherELQARLQQAAESFRQE 741
Cdd:COG1196   519 LRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPL---DKIRARAALAAALARG 595
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  742 REGLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALEKEELREELSEHHRRELQEGREEMETEcNRRVSQIEAQCQADCEKV 821
Cdd:COG1196   596 AIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGG-SAGGSLTGGSRRELLAAL 674
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  822 TEHcEQTLQSLEVRHRQELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRERATAAAMKQEQEILERTYKDRL 901
Cdd:COG1196   675 LEA-EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAL 753
                         570       580
                  ....*....|....*....|..
gi 554506543  902 NILSTE--RKQLLQDLKDLQNA 921
Cdd:COG1196   754 EELPEPpdLEELERELERLERE 775
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1435-1735 7.61e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 7.61e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1435 LQQEATIAELELEKQKLQELTRNLRERVTALvrqKDAPSQGQKE-EELKAMMQDLQITCGEMQRKVELLRYESEKLQEEN 1513
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEKALAEL---RKELEELEEElEQLRKELEELSRQISALRKDLARLEAEVEQLEERI 749
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1514 SILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQ-------EKASIQTMVEKLKKQVSDLKIKNQQLDSENIEL 1586
Cdd:TIGR02168  750 AQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAqieqlkeELKALREALDELRAELTLLNEEAANLRERLESL 829
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1587 SQKNSQNKEELKTLNQRLAEMLCQREEPGACTSEKWEQENAsLKEELDHY---KVQTSTLVSSLEAELSEVKLQTHVMEQ 1663
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE-LESELEALlneRASLEEALALLRSELEELSEELRELES 908
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 554506543  1664 ENLLLKDELERLKQLhrcpdLSDFQQKMSS----ILSYNEKLLKEKEVLSEELKSCADKL-AESSLLEHRIATMKQE 1735
Cdd:TIGR02168  909 KRSELRRELEELREK-----LAQLELRLEGlevrIDNLQERLSEEYSLTLEEAEALENKIeDDEEEARRRLKRLENK 980
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1725-1909 7.28e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 7.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1725 LEHRIATMKQEQTAWEEQSESLKSQLAVSQAKVQNLEDVLQNVNLQMAEIESDLQVTRQEKEALKQEVMSLHRQLQNAID 1804
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLR 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1805 KDWVSETAPHLSGLRGQQ------RRLSWdkLDHLMN------EEPQLLCQESKRLQTVVQNTQADLTHSREKVRQLESN 1872
Cdd:COG4942   112 ALYRLGRQPPLALLLSPEdfldavRRLQY--LKYLAParreqaEELRADLAELAALRAELEAERAELEALLAELEEERAA 189
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 554506543 1873 LLPTKHQKQLnqpcTVKSTEQEKLTLKRECEQSQKEQ 1909
Cdd:COG4942   190 LEALKAERQK----LLARLEKELAELAAELAELQQEA 222
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
665-1322 4.10e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.44  E-value: 4.10e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  665 LEKRVSELRSEIADLEGQAAVLREAhhkascrheeekRQLQmafdEEKAQLQEELRQEHERELQARLQQAAESFRQEREG 744
Cdd:COG1196   191 LEDILGELERQLEPLERQAEKAERY------------RELK----EELKELEAELLLLKLRELEAELEELEAELEELEAE 254
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  745 LAQAawtEEKVRGLEQSYQEQLLSLEEKhalekeelreelsehhRRELQEGREEmETECNRRVSQIEAQCQADCEKvteh 824
Cdd:COG1196   255 LEEL---EAELAELEAELEELRLELEEL----------------ELELEEAQAE-EYELLAELARLEQDIARLEER---- 310
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  825 ceqtlqslevrhRQELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRERATAAAMKQEQEILERTYKDRLNIL 904
Cdd:COG1196   311 ------------RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  905 STERKQLLQDLKDLQNASESQHgllsgQILELKRSQERELRDQGQALcQTGVSEQLASQQLERLRVEHEQERREMTGKLA 984
Cdd:COG1196   379 EELEELAEELLEALRAAAELAA-----QLEELEEAEEALLERLERLE-EELEELEEALAELEEEEEEEEEALEEAAEEEA 452
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  985 ALESAHRASLERADQEKAEMSTEICRLQNTVKDMQQAASLLMLQGGCQATAGEEAEGDGAMSLLQQGEQLLEEnGDVLIS 1064
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGA-VAVLIG 531
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1065 LQRAHEHAVKenakmATEISRLQQRLKKLEpgSVISSCLEEGTSEISGSSREQVEPIMKQGPATKHFLSDLGDHEARDLA 1144
Cdd:COG1196   532 VEAAYEAALE-----AALAAALQNIVVEDD--EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV 604
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1145 StgTSSVQRQECKTEASEASLDCFSELENSEDTRTESWDLKSQISQLREQLTVLRADCDRASERKQDLLFDISVLKKKLK 1224
Cdd:COG1196   605 A--SDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE 682
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1225 MLERlpEASSRYKVLYEDAARENSCLQEELRLVETRYEESLDSNKELTAEVYRLQDEMKKMEEVMETFLSLEKSYDEVKV 1304
Cdd:COG1196   683 ELAE--RLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP 760
                         650
                  ....*....|....*...
gi 554506543 1305 ENEELRALVLRLQGKMEK 1322
Cdd:COG1196   761 DLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
344-921 1.84e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.13  E-value: 1.84e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  344 LALENELLVTKNGIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRN--EYNLRK 421
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQaeEYELLA 295
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  422 LDEEYKERIAALKnELRQEREQMLQQVGKQRVELEQEIQKAKTEENYIRDRLALSLKENNRLETELLENAEKLAEYESLT 501
Cdd:COG1196   296 ELARLEQDIARLE-ERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  502 QKLQRSLENVLAEKFGDLDpSSAEFFLQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPLKNSLSEELd 581
Cdd:COG1196   375 AEAEEELEELAEELLEALR-AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA- 452
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  582 ghsggiepdqgpgsEECNPLNMSIEAELVIEQMKEQHHRDLCHLRLELEDKVRHYEKQLDDTRVASEQEQAAMKQKYEQG 661
Cdd:COG1196   453 --------------ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  662 VHTLEKRVSELRSEIADLEGQAAVLREAHHKASCRHEEEKRQLQMAFDEEKAQLQEELRQEherELQARLQQAAESFRQE 741
Cdd:COG1196   519 LRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPL---DKIRARAALAAALARG 595
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  742 REGLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALEKEELREELSEHHRRELQEGREEMETEcNRRVSQIEAQCQADCEKV 821
Cdd:COG1196   596 AIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGG-SAGGSLTGGSRRELLAAL 674
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  822 TEHcEQTLQSLEVRHRQELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRERATAAAMKQEQEILERTYKDRL 901
Cdd:COG1196   675 LEA-EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAL 753
                         570       580
                  ....*....|....*....|..
gi 554506543  902 NILSTE--RKQLLQDLKDLQNA 921
Cdd:COG1196   754 EELPEPpdLEELERELERLERE 775
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1435-1735 7.61e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 7.61e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1435 LQQEATIAELELEKQKLQELTRNLRERVTALvrqKDAPSQGQKE-EELKAMMQDLQITCGEMQRKVELLRYESEKLQEEN 1513
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEKALAEL---RKELEELEEElEQLRKELEELSRQISALRKDLARLEAEVEQLEERI 749
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1514 SILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQ-------EKASIQTMVEKLKKQVSDLKIKNQQLDSENIEL 1586
Cdd:TIGR02168  750 AQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAqieqlkeELKALREALDELRAELTLLNEEAANLRERLESL 829
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1587 SQKNSQNKEELKTLNQRLAEMLCQREEPGACTSEKWEQENAsLKEELDHY---KVQTSTLVSSLEAELSEVKLQTHVMEQ 1663
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE-LESELEALlneRASLEEALALLRSELEELSEELRELES 908
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 554506543  1664 ENLLLKDELERLKQLhrcpdLSDFQQKMSS----ILSYNEKLLKEKEVLSEELKSCADKL-AESSLLEHRIATMKQE 1735
Cdd:TIGR02168  909 KRSELRRELEELREK-----LAQLELRLEGlevrIDNLQERLSEEYSLTLEEAEALENKIeDDEEEARRRLKRLENK 980
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
697-1607 1.55e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.62  E-value: 1.55e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   697 HEEEKRQLQMAfdEEKAQLQEELRQEHERELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALe 776
Cdd:TIGR02168  195 LNELERQLKSL--ERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEE- 271
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   777 keelreelsehHRRELQEGREEMET------ECNRRVSQIEAQCQADCEKVtEHCEQTLQSLEVRHRQELRDLLDQhLEE 850
Cdd:TIGR02168  272 -----------LRLEVSELEEEIEElqkelyALANEISRLEQQKQILRERL-ANLERQLEELEAQLEELESKLDEL-AEE 338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   851 RSQWEFEKDELTQECTDAQEQLKEAlqrerataAAMKQEQEILERTYKDRLNILSTERKQLLQDLKDLQNasesQHGLLS 930
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEEL--------EAELEELESRLEELEEQLETLRSKVAQLELQIASLNN----EIERLE 406
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   931 GQILELKRSQERELRDQGQALcqtgvsEQLASQQLERLRVEHEQERREMTGKLAALEsAHRASLERADQEKAEMSTEIcr 1010
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELL------KKLEEAELKELQAELEELEEELEELQEELE-RLEEALEELREELEEAEQAL-- 477
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1011 lqntvkdmqqaasllmlqggcQATAGEEAEGDGAMSLLQQGEQLLEENGDvlislqrahehAVKENAKMATEISRLQQRL 1090
Cdd:TIGR02168  478 ---------------------DAAERELAQLQARLDSLERLQENLEGFSE-----------GVKALLKNQSGLSGILGVL 525
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1091 KKL---EPG--SVISSCLEEGTSEISGSSREQVEPI---MKQGPATKHFLSDLGDHEARDLASTGTSSVQRQECktease 1162
Cdd:TIGR02168  526 SELisvDEGyeAAIEAALGGRLQAVVVENLNAAKKAiafLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEG------ 599
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1163 aSLDCFSELENSEDtrteswDLKSQISQLREQLTVLrADCDRASE--RKQDLLFDISVLKKKLkmlerlpeASSRYKVLY 1240
Cdd:TIGR02168  600 -FLGVAKDLVKFDP------KLRKALSYLLGGVLVV-DDLDNALElaKKLRPGYRIVTLDGDL--------VRPGGVITG 663
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1241 EDAARENSCLqeelrlvetryeesldsnkELTAEVYRLQDEMKKMEEvmeTFLSLEKSYDEVKVENEELRALVLRLQGKM 1320
Cdd:TIGR02168  664 GSAKTNSSIL-------------------ERRREIEELEEKIEELEE---KIAELEKALAELRKELEELEEELEQLRKEL 721
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1321 EKVLGRAALQGDSYALWEAPSENLEvasdEKMLELRQTPKECTPKVVSMHHIIEECTQETQCCEQGSTKLLARIKAHEIA 1400
Cdd:TIGR02168  722 EELSRQISALRKDLARLEAEVEQLE----ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE 797
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1401 WFhraikthpekpsaqnrvipEGSAALLGLQDKHLQQEATIAELELEKQKLQELTRNLRERVTALVRQKDAPSqgQKEEE 1480
Cdd:TIGR02168  798 LK-------------------ALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS--EDIES 856
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1481 LKAMMQDLQITCGEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQT 1560
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEV 936
                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*...
gi 554506543  1561 MVEKLKKQVSDLKIKNQQLDSENIELSQKNSQN-KEELKTLNQRLAEM 1607
Cdd:TIGR02168  937 RIDNLQERLSEEYSLTLEEAEALENKIEDDEEEaRRRLKRLENKIKEL 984
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
1010-1789 3.11e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.98  E-value: 3.11e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1010 RLQNTVKDMQQAASLlmlQGGCQATAGEEAEGDGAMSLLQQGeqLLEENGDVLISLQRAHEHAVKENAKMATEISRlqqr 1089
Cdd:pfam15921  146 QLQNTVHELEAAKCL---KEDMLEDSNTQIEQLRKMMLSHEG--VLQEIRSILVDFEEASGKKIYEHDSMSTMHFR---- 216
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1090 lkklEPGSVISSCLEEGTSEISgSSREQVEPIMKQGPATKHflsdlgdhEARDLASTgtsSVQRQECKTEA--SEASLDC 1167
Cdd:pfam15921  217 ----SLGSAISKILRELDTEIS-YLKGRIFPVEDQLEALKS--------ESQNKIEL---LLQQHQDRIEQliSEHEVEI 280
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1168 FSELENSEDTRTESWDLKSQISQLREQLtvlRADCDRASERKQDLLFDISVLKKKLKMLERLpeassrykvlYEDAAREn 1247
Cdd:pfam15921  281 TGLTEKASSARSQANSIQSQLEIIQEQA---RNQNSMYMRQLSDLESTVSQLRSELREAKRM----------YEDKIEE- 346
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1248 scLQEELRLVETRYEESLDSNKELTAEVYRLQDEMKKMEEVM---ETFLSLEKS----------------------YDEV 1302
Cdd:pfam15921  347 --LEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLhkrEKELSLEKEqnkrlwdrdtgnsitidhlrreLDDR 424
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1303 KVENEELRALVLRL----QGKMEKVLgrAALQGDSYALWEAPSENLEVASDEKMLelRQTPKECTPKVVSMhhiieectq 1378
Cdd:pfam15921  425 NMEVQRLEALLKAMksecQGQMERQM--AAIQGKNESLEKVSSLTAQLESTKEML--RKVVEELTAKKMTL--------- 491
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1379 etQCCEQGSTKLLARIKAHEiawfhRAIK-THPEKPSAQNRVipegSAALLGLQD--------KHLQQEATIAELEL-EK 1448
Cdd:pfam15921  492 --ESSERTVSDLTASLQEKE-----RAIEaTNAEITKLRSRV----DLKLQELQHlknegdhlRNVQTECEALKLQMaEK 560
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1449 QKLQELTRNLRERVTALVrqkdapsqGQKEEELKAMmqdlQITCGEMQRKVELLRYESEKLQEENSILRNEITTLneEDS 1528
Cdd:pfam15921  561 DKVIEILRQQIENMTQLV--------GQHGRTAGAM----QVEKAQLEKEINDRRLELQEFKILKDKKDAKIREL--EAR 626
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1529 ISNLKLEEL---NGSQEELwQKIETIEQEKASIQTMVEKLKKQVSDLkiknqqldSENIELSQKNSQNK-EELKTlnqrl 1604
Cdd:pfam15921  627 VSDLELEKVklvNAGSERL-RAVKDIKQERDQLLNEVKTSRNELNSL--------SEDYEVLKRNFRNKsEEMET----- 692
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1605 aemlcqreepgacTSEKWEQENASLKEELDhykvQTSTLVSSLEAELSEVKLQTHVMEQENLLLKDELERLkqlhrcpdl 1684
Cdd:pfam15921  693 -------------TTNKLKMQLKSAQSELE----QTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDAL--------- 746
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1685 sdfQQKMSSILSYNEKLLKEKEVLSEElkscadklaeSSLLEHRIATMKQEQTAWEEQSESLKSQLAVSQAKVQNLEDVL 1764
Cdd:pfam15921  747 ---QSKIQFLEEAMTNANKEKHFLKEE----------KNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVAL 813
                          810       820
                   ....*....|....*....|....*
gi 554506543  1765 QNVNLQMAEIESDLQvtRQEKEALK 1789
Cdd:pfam15921  814 DKASLQFAECQDIIQ--RQEQESVR 836
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
320-911 3.80e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 3.80e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   320 ENSQEILKALDFSLDGNINLTELTLALENELLVTKNGIHQAALASFKA---EIRHLLERVDQVVREKEKLRSDLDKAEKL 396
Cdd:TIGR02168  329 ESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEleeQLETLRSKVAQLELQIASLNNEIERLEAR 408
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   397 KSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRQ------EREQMLQQVGKQRVELEQEIQKAKTEENYIR 470
Cdd:TIGR02168  409 LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEElqeeleRLEEALEELREELEEAEQALDAAERELAQLQ 488
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   471 DRLALSLKENNRLET------ELLENAEKLAEYESL-------TQKLQRSLENVLAEKFGDLDPSSAEF------FLQEE 531
Cdd:TIGR02168  489 ARLDSLERLQENLEGfsegvkALLKNQSGLSGILGVlselisvDEGYEAAIEAALGGRLQAVVVENLNAakkaiaFLKQN 568
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   532 RL------------AQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVL----------------RLPLKNSLSEE---- 579
Cdd:TIGR02168  569 ELgrvtflpldsikGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvvddldnALELAKKLRPGyriv 648
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   580 -LDGH---SGGIEpDQGPGSEECNPLNMSIEAELVIEQMKEQHH--RDLCHLRLELEDKVRHYEKQLDDTRVASEQ---- 649
Cdd:TIGR02168  649 tLDGDlvrPGGVI-TGGSAKTNSSILERRREIEELEEKIEELEEkiAELEKALAELRKELEELEEELEQLRKELEElsrq 727
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   650 --EQAAMKQKYEQGVHTLEKRVSELRSEIADLEGQAAVLREAHHKASCRHEEEKRQLQmAFDEEKAQLQEELRQEHER-- 725
Cdd:TIGR02168  728 isALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE-ELEAQIEQLKEELKALREAld 806
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   726 ELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQLLSLEEkhalekeelREELSEHHRRELQEGREEMETECNr 805
Cdd:TIGR02168  807 ELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE---------DIESLAAEIEELEELIEELESELE- 876
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   806 RVSQIEAQCQADCEKVTEHCEQ---TLQSLEvRHRQELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRERAT 882
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEElseELRELE-SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEE 955
                          650       660
                   ....*....|....*....|....*....
gi 554506543   883 AAAMKQEQEILERTYKDRLNILSTERKQL 911
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1433-1766 1.36e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 1.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1433 KHLQQEATIAElelekqKLQELTRNLRERvtalvrqkdapsqgqKEEELKAMMQDLQITCGEMQRKVELLRYESEKLQEE 1512
Cdd:COG1196   203 EPLERQAEKAE------RYRELKEELKEL---------------EAELLLLKLRELEAELEELEAELEELEAELEELEAE 261
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1513 NSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASiqtmvekLKKQVSDLKIKNQQLDSENIELSQKNSQ 1592
Cdd:COG1196   262 LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIAR-------LEERRRELEERLEELEEELAELEEELEE 334
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1593 NKEELKTLNQRLAEMLCQREEPGAC---TSEKWEQENASLKEELDHYKVQTSTLVSSLEAELSEVKLQTHVMEQENLLLK 1669
Cdd:COG1196   335 LEEELEELEEELEEAEEELEEAEAElaeAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1670 DELERLKQLhrcpdlsdfQQKMSSILSYNEKLLKEKEVLSEELKSCADKLAESSLLEHRIATMKQEQTAWEEQSESLKSQ 1749
Cdd:COG1196   415 RLERLEEEL---------EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485
                         330
                  ....*....|....*..
gi 554506543 1750 LAVSQAKVQNLEDVLQN 1766
Cdd:COG1196   486 LAEAAARLLLLLEAEAD 502
PLN02939 PLN02939
transferase, transferring glycosyl groups
1462-1800 2.83e-07

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 56.06  E-value: 2.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1462 VTALVRQKDAPSQGQKEEELKAMMQDLQITCGEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQ 1541
Cdd:PLN02939   33 VSCRARRRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHNRASMQRDEAIAAID 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1542 EELWQKIETIEQEkASIQ-----TMVEKLKKQVSDL-KIKNQQLDSENIELSQKNSQNKEeLKTLNQRLAEMLCQRE--E 1613
Cdd:PLN02939  113 NEQQTNSKDGEQL-SDFQledlvGMIQNAEKNILLLnQARLQALEDLEKILTEKEALQGK-INILEMRLSETDARIKlaA 190
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1614 PGACTSEKWEQENASLKEELDHYKVQTSTLVSSLEAELSEVKLqthvmeqENLLLKDELERLKQlhrcpDLSDFQQKMSS 1693
Cdd:PLN02939  191 QEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKE-------ENMLLKDDIQFLKA-----ELIEVAETEER 258
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1694 ILsyneKLLKEKEVLSEELKSCADKLAESSLLEHRIATMKQEqtAWEEQSESLKSQLAVSQAKVQNLEDVL-QNVNL--Q 1770
Cdd:PLN02939  259 VF----KLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYD--CWWEKVENLQDLLDRATNQVEKAALVLdQNQDLrdK 332
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 554506543 1771 MAEIESDLQVTRQEK------EALKQEVMSLHRQLQ 1800
Cdd:PLN02939  333 VDKLEASLKEANVSKfssykvELLQQKLKLLEERLQ 368
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
315-947 4.69e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.36  E-value: 4.69e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   315 QEEGIENSQEILKALDFSLDGNINLTELTLALENELLVTKNGIHQAALAsfKAEIRHLLERVDQVVREKEKLRSDLDKAE 394
Cdd:pfam02463  276 EEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK--KAEKELKKEKEEIEELEKELKELEIKREA 353
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   395 KLKSLMASEvddhhaAIERRNEYNLRKLDEEYKERIAALKNELRQEREQMlqqvgkqrvELEQEIQKAKTEENYIRDRLA 474
Cdd:pfam02463  354 EEEEEEELE------KLQEKLEQLEEELLAKKKLESERLSSAAKLKEEEL---------ELKSEEEKEAQLLLELARQLE 418
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   475 LSLKENNRLETELLENAEKLAEYESLTQKLQRSLENVLAEKFGDLDPSSAEFFLQEERLAQMRNEYEQQCRLLQDQVDEL 554
Cdd:pfam02463  419 DLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEER 498
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   555 QSELEEYQAQGRVLRLPLKNSLSEELDGHSGGIEpDQGPGSEECNPLNMSIEAELVIEQMKEQHHRDLCHLRLELEDKVR 634
Cdd:pfam02463  499 SQKESKARSGLKVLLALIKDGVGGRIISAHGRLG-DLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGA 577
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   635 HYEKQLDDTRVASEQEQAAMKQKYEQGVHTLEKRVSELRSEIA-------DLEGQAAVLREAHHKASCRHEEEKRQLQMA 707
Cdd:pfam02463  578 RKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKrakvvegILKDTELTKLKESAKAKESGLRKGVSLEEG 657
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   708 FDEEKAQLQEELRQEHERELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALEKEELREELSEH 787
Cdd:pfam02463  658 LAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEE 737
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   788 HRRELQEGREEMETECNRRVSQIEAQCQADCEKVTEHCEQTLQSLEVRHRQELRDLLDQHLEERSQWEFEKDELTQECTD 867
Cdd:pfam02463  738 LKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELL 817
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   868 AQEQLKEALQRERATAAAMKQEQEILERTYKDRLNILSTERKQLLQdLKDLQNASESQHGLLSGQILELKRSQERELRDQ 947
Cdd:pfam02463  818 EEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEI-TKEELLQELLLKEEELEEQKLKDELESKEEKEK 896
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
368-581 1.06e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 50.70  E-value: 1.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  368 EIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALkNELRQEREQMLQQ 447
Cdd:PRK05771   44 RLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEI-SELENEIKELEQE 122
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  448 vgKQRVE----LEQEIQKAKTEENYIrdRLALSLKENNRLETELLENAEKLAEYESLTQKL------QRSLENVLAEKFG 517
Cdd:PRK05771  123 --IERLEpwgnFDLDLSLLLGFKYVS--VFVGTVPEDKLEELKLESDVENVEYISTDKGYVyvvvvvLKELSDEVEEELK 198
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 554506543  518 DLDPSSAEFFlQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPLKNSLSEELD 581
Cdd:PRK05771  199 KLGFERLELE-EEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEIELE 261
PTZ00121 PTZ00121
MAEBL; Provisional
638-1322 2.21e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 2.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  638 KQLDDTRVASEQEQAAMKQKYEQGVHTLEKRvselRSEIADLEGQAAVLREAHHKASCRHEEEKRQLQMAFDEEKAQLQE 717
Cdd:PTZ00121 1104 KKTETGKAEEARKAEEAKKKAEDARKAEEAR----KAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAE 1179
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  718 ELRQEHERELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALEKEELREELSEHHRRELQEGRE 797
Cdd:PTZ00121 1180 AARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEE 1259
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  798 EMETECNRRVSQIEAQCQADCEKVTEhCEQTLQSLEVRHRQELR--DLLDQHLEERSQWEFEKDELTQECTDAQEQLKEA 875
Cdd:PTZ00121 1260 ARMAHFARRQAAIKAEEARKADELKK-AEEKKKADEAKKAEEKKkaDEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKA 1338
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  876 LQRERATAAAMKQEQEILERTYKdrlnilsTERKQLLQDLKDLQNASESQHglLSGQILELKRSQERelrdQGQALCQTG 955
Cdd:PTZ00121 1339 EEAKKAAEAAKAEAEAAADEAEA-------AEEKAEAAEKKKEEAKKKADA--AKKKAEEKKKADEA----KKKAEEDKK 1405
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  956 VSEQLASQQLERLRVEHEQERREMTGKlaALESAHRASLERADQEKAEMSTEICRLQNTVKDMQQAASLLMLqggcQATA 1035
Cdd:PTZ00121 1406 KADELKKAAAAKKKADEAKKKAEEKKK--ADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEA----KKKA 1479
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1036 GEEAEGDGAMSLLQQGEQLLEENGDVLISLQRAHEHAVKENAKMATEISRLQQRLKKLEpgsvisscLEEGTSEISGSSR 1115
Cdd:PTZ00121 1480 EEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADE--------AKKAEEKKKADEL 1551
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1116 EQVEPIMKQGPATKHflsdlgdHEARDLASTGTSSVQRQECKTEASEASLDCFSELENSEDTrteswdLKSQISQLREQL 1195
Cdd:PTZ00121 1552 KKAEELKKAEEKKKA-------EEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKK------MKAEEAKKAEEA 1618
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1196 TVLRADCDRASERKQDLLFDISVLKKKLKMLERLPEASSRYKVLYEDAARENsclQEELRLVETRYEESLDSNKELTAeV 1275
Cdd:PTZ00121 1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA---EEDKKKAEEAKKAEEDEKKAAEA-L 1694
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*..
gi 554506543 1276 YRLQDEMKKMEEVMETFLSLEKSYDEVKVENEELRALVLRLQGKMEK 1322
Cdd:PTZ00121 1695 KKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE 1741
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
1443-1825 1.03e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.42  E-value: 1.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1443 ELELEKQKLQEL-TRNLRERVTALVRQKDAPSQGQKEEELKAMMQDLQITC-GEMQRKVELLRYESEKLQEENSIL---- 1516
Cdd:pfam15921  392 ELSLEKEQNKRLwDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECqGQMERQMAAIQGKNESLEKVSSLTaqle 471
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1517 --RNEITTLNEEDSISNLKLE-------ELNGSQEELWQKIETIEQEKASIQTMVEKLKKQVSDLKIKNQQLDSENIE-- 1585
Cdd:pfam15921  472 stKEMLRKVVEELTAKKMTLEssertvsDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTEce 551
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1586 -LSQKNSQNKEELKTLNQRLAEMLCQREEPGAcTSEKWEQENASLKEELDHYKVQTStlvsslEAELSEVKLQTHVMEQE 1664
Cdd:pfam15921  552 aLKLQMAEKDKVIEILRQQIENMTQLVGQHGR-TAGAMQVEKAQLEKEINDRRLELQ------EFKILKDKKDAKIRELE 624
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1665 NLLLKDELERLKQLH----RCPDLSDFQQKMSSIL-----SYNE--KLLKEKEVL-------SEELKSCADKL-----AE 1721
Cdd:pfam15921  625 ARVSDLELEKVKLVNagseRLRAVKDIKQERDQLLnevktSRNElnSLSEDYEVLkrnfrnkSEEMETTTNKLkmqlkSA 704
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1722 SSLLEHRIATMKQEQTA----------WEEQSESLKSQLAVSQAKVQNLEDVLQNVNlqmaeiesdlqvtrQEKEALKQE 1791
Cdd:pfam15921  705 QSELEQTRNTLKSMEGSdghamkvamgMQKQITAKRGQIDALQSKIQFLEEAMTNAN--------------KEKHFLKEE 770
                          410       420       430
                   ....*....|....*....|....*....|....
gi 554506543  1792 VMSLHRQLQNAIDKDwvSETAPHLSGLRGQQRRL 1825
Cdd:pfam15921  771 KNKLSQELSTVATEK--NKMAGELEVLRSQERRL 802
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1725-1909 7.28e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 7.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1725 LEHRIATMKQEQTAWEEQSESLKSQLAVSQAKVQNLEDVLQNVNLQMAEIESDLQVTRQEKEALKQEVMSLHRQLQNAID 1804
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLR 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1805 KDWVSETAPHLSGLRGQQ------RRLSWdkLDHLMN------EEPQLLCQESKRLQTVVQNTQADLTHSREKVRQLESN 1872
Cdd:COG4942   112 ALYRLGRQPPLALLLSPEdfldavRRLQY--LKYLAParreqaEELRADLAELAALRAELEAERAELEALLAELEEERAA 189
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 554506543 1873 LLPTKHQKQLnqpcTVKSTEQEKLTLKRECEQSQKEQ 1909
Cdd:COG4942   190 LEALKAERQK----LLARLEKELAELAAELAELQQEA 222
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
665-1322 4.10e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.44  E-value: 4.10e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  665 LEKRVSELRSEIADLEGQAAVLREAhhkascrheeekRQLQmafdEEKAQLQEELRQEHERELQARLQQAAESFRQEREG 744
Cdd:COG1196   191 LEDILGELERQLEPLERQAEKAERY------------RELK----EELKELEAELLLLKLRELEAELEELEAELEELEAE 254
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  745 LAQAawtEEKVRGLEQSYQEQLLSLEEKhalekeelreelsehhRRELQEGREEmETECNRRVSQIEAQCQADCEKvteh 824
Cdd:COG1196   255 LEEL---EAELAELEAELEELRLELEEL----------------ELELEEAQAE-EYELLAELARLEQDIARLEER---- 310
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  825 ceqtlqslevrhRQELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRERATAAAMKQEQEILERTYKDRLNIL 904
Cdd:COG1196   311 ------------RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  905 STERKQLLQDLKDLQNASESQHgllsgQILELKRSQERELRDQGQALcQTGVSEQLASQQLERLRVEHEQERREMTGKLA 984
Cdd:COG1196   379 EELEELAEELLEALRAAAELAA-----QLEELEEAEEALLERLERLE-EELEELEEALAELEEEEEEEEEALEEAAEEEA 452
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  985 ALESAHRASLERADQEKAEMSTEICRLQNTVKDMQQAASLLMLQGGCQATAGEEAEGDGAMSLLQQGEQLLEEnGDVLIS 1064
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGA-VAVLIG 531
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1065 LQRAHEHAVKenakmATEISRLQQRLKKLEpgSVISSCLEEGTSEISGSSREQVEPIMKQGPATKHFLSDLGDHEARDLA 1144
Cdd:COG1196   532 VEAAYEAALE-----AALAAALQNIVVEDD--EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV 604
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1145 StgTSSVQRQECKTEASEASLDCFSELENSEDTRTESWDLKSQISQLREQLTVLRADCDRASERKQDLLFDISVLKKKLK 1224
Cdd:COG1196   605 A--SDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE 682
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1225 MLERlpEASSRYKVLYEDAARENSCLQEELRLVETRYEESLDSNKELTAEVYRLQDEMKKMEEVMETFLSLEKSYDEVKV 1304
Cdd:COG1196   683 ELAE--RLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP 760
                         650
                  ....*....|....*...
gi 554506543 1305 ENEELRALVLRLQGKMEK 1322
Cdd:COG1196   761 DLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
373-1003 1.22e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.90  E-value: 1.22e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  373 LERVDQVVREKEK----LRSDLDKAEKLKSLMASEVD-DHHAAIERRNEYNLRKldEEYKERIAALKNELRQEREQmLQQ 447
Cdd:COG1196   188 LERLEDILGELERqlepLERQAEKAERYRELKEELKElEAELLLLKLRELEAEL--EELEAELEELEAELEELEAE-LAE 264
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  448 VGKQRVELEQEIQKAKTEENYIRDRLALSLKENNRLETELLENAEKLAEYESLTQKLQRSLENVLAEKfgdldpssAEFF 527
Cdd:COG1196   265 LEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEEL--------EELE 336
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  528 LQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQgrvlrlplknslseeldghsggiepdqgpgseecnplnmSIEA 607
Cdd:COG1196   337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE---------------------------------------LAEA 377
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  608 ELVIEQMKEQHHRDLcHLRLELEDKVRHYEKQLDDTRVASEQEQAAMKQKYEQGVHTLEKRVSELRSEIADLEGQAAVLR 687
Cdd:COG1196   378 EEELEELAEELLEAL-RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  688 EAHhkascRHEEEKRQLQMAFDEEKAQLQEELRQEHERELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQLL 767
Cdd:COG1196   457 EEE-----ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG 531
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  768 SLEEKHALEKEELREELSEHHRRELQEGREEMETECNRRVSQIEAQCQADCEKVTEHCEQTLQSLEVRHRQELRDLLDQH 847
Cdd:COG1196   532 VEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  848 LEERSQWEFEKDELTQECTD---AQEQLKEALQRERATAAAMKQEQEILERTYKDRLNILSTERKQLLQDlkDLQNASES 924
Cdd:COG1196   612 DARYYVLGDTLLGRTLVAARleaALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAEL--EELAERLA 689
                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 554506543  925 QHGLLSGQILELKRSQERELRDQGQALCQTGVSEQLASQQLERLRVEHEQERREMTGKLAALESAHRASLERADQEKAE 1003
Cdd:COG1196   690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
344-921 1.84e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.13  E-value: 1.84e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  344 LALENELLVTKNGIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRN--EYNLRK 421
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQaeEYELLA 295
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  422 LDEEYKERIAALKnELRQEREQMLQQVGKQRVELEQEIQKAKTEENYIRDRLALSLKENNRLETELLENAEKLAEYESLT 501
Cdd:COG1196   296 ELARLEQDIARLE-ERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  502 QKLQRSLENVLAEKFGDLDpSSAEFFLQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPLKNSLSEELd 581
Cdd:COG1196   375 AEAEEELEELAEELLEALR-AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA- 452
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  582 ghsggiepdqgpgsEECNPLNMSIEAELVIEQMKEQHHRDLCHLRLELEDKVRHYEKQLDDTRVASEQEQAAMKQKYEQG 661
Cdd:COG1196   453 --------------ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  662 VHTLEKRVSELRSEIADLEGQAAVLREAHHKASCRHEEEKRQLQMAFDEEKAQLQEELRQEherELQARLQQAAESFRQE 741
Cdd:COG1196   519 LRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPL---DKIRARAALAAALARG 595
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  742 REGLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALEKEELREELSEHHRRELQEGREEMETEcNRRVSQIEAQCQADCEKV 821
Cdd:COG1196   596 AIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGG-SAGGSLTGGSRRELLAAL 674
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  822 TEHcEQTLQSLEVRHRQELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRERATAAAMKQEQEILERTYKDRL 901
Cdd:COG1196   675 LEA-EAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAL 753
                         570       580
                  ....*....|....*....|..
gi 554506543  902 NILSTE--RKQLLQDLKDLQNA 921
Cdd:COG1196   754 EELPEPpdLEELERELERLERE 775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
425-1095 1.13e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.43  E-value: 1.13e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  425 EYKERIAALKNELRQEREQM------LQQVGKQRVELEQEIQKAKTeenyirdrlALSLKEnnrlETELLENAEKLAEYE 498
Cdd:COG1196   169 KYKERKEEAERKLEATEENLerlediLGELERQLEPLERQAEKAER---------YRELKE----ELKELEAELLLLKLR 235
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  499 SLTQKLQRSLENVLAEKfgdldpssaeffLQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQgrvlrlplKNSLSE 578
Cdd:COG1196   236 ELEAELEELEAELEELE------------AELEELEAELAELEAELEELRLELEELELELEEAQAE--------EYELLA 295
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  579 ELDGHSGGIEPDQgpgsEECNPLNMSIEAELVIEQMKEQHHRDLCHLRLELEDKVRHYEKQLDDTRVASEQEQAAMKQKy 658
Cdd:COG1196   296 ELARLEQDIARLE----ERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA- 370
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  659 EQGVHTLEKRVSELRSEIADLEGQAAVLREAHHKASCRHEEEKRQLQMAFDEEKAQLQEELRQEHER-ELQARLQQAAES 737
Cdd:COG1196   371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEeEEEEALEEAAEE 450
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  738 FRQEREGLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALEKEELREELSEHHRRE--LQEGREEMETECNRRVSQIEAQCQ 815
Cdd:COG1196   451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgfLEGVKAALLLAGLRGLAGAVAVLI 530
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  816 ADCEKVTEHCEQTLQSLEVrhrqelRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRERATAAAMKQEQEILER 895
Cdd:COG1196   531 GVEAAYEAALEAALAAALQ------NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV 604
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  896 TYKDRLNILSTERKQLLQDLKDLQNASESQHGLLSGQILELKRSQERELRDQGQALCQTGVSEQLASQQLERLRVEHEQE 975
Cdd:COG1196   605 ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL 684
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  976 RREMTGKLAALESAHRASLERADQEKAEMSTEIcrlqntvkdmqqaasllmlqggcQATAGEEAEGDGAMSLLQQGEQLL 1055
Cdd:COG1196   685 AERLAEEELELEEALLAEEEEERELAEAEEERL-----------------------EEELEEEALEEQLEAEREELLEEL 741
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|
gi 554506543 1056 EENGDVLISLQRAHEHAVKENAKMATEISRLQQRLKKLEP 1095
Cdd:COG1196   742 LEEEELLEEEALEELPEPPDLEELERELERLEREIEALGP 781
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
607-1228 6.71e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.12  E-value: 6.71e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  607 AELVIEQMKEQHHRDLCHLRLELEDKVRHYEKQLDDTRVASEQEQAAMKQkyeqgVHTLEKRVSELRSEIADLEGQAAVL 686
Cdd:COG1196   212 AERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAE-----LAELEAELEELRLELEELELELEEA 286
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  687 REAHHKASCRHEEEKRQLQMAfDEEKAQLQEELRQEHERELQARLQQAAESFRQEREgLAQAAWTEEKVRGLEQSYQEQL 766
Cdd:COG1196   287 QAEEYELLAELARLEQDIARL-EERRRELEERLEELEEELAELEEELEELEEELEEL-EEELEEAEEELEEAEAELAEAE 364
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  767 LSLEEKHAlEKEELREELSEHHRRELQEGREEMETEcnRRVSQIEAQcqadcekvtehcEQTLQSLEVRHRQELRDLLDQ 846
Cdd:COG1196   365 EALLEAEA-ELAEAEEELEELAEELLEALRAAAELA--AQLEELEEA------------EEALLERLERLEEELEELEEA 429
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  847 HLEERSqwefEKDELTQECTDAQEQLKEALQRERATAAAMKQEQEILERtYKDRLNILSTERKQLLQDLKDLQNASESQH 926
Cdd:COG1196   430 LAELEE----EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL-LEAALAELLEELAEAAARLLLLLEAEADYE 504
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  927 GLLSGQILELKRSQERELRDQGQALCQTGVSEQLASQQLERLRVEHEQERREMTGKlAALESAHRASLERADQEKAemst 1006
Cdd:COG1196   505 GFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAA-AAIEYLKAAKAGRATFLPL---- 579
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1007 eicrlqNTVKDMQQAASLLMLQGGCQATAGEEAEgdgamslLQQGEQLLEENGDVLISLQRAHEHAVKENAKMATEISRL 1086
Cdd:COG1196   580 ------DKIRARAALAAALARGAIGAAVDLVASD-------LREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRL 646
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1087 QQRLKKLEPGSVISSCLEEGTSEISGSSREQVEpimkqgpatkhFLSDLGDHEARDLASTGTSSVQRQECKTEASEASLD 1166
Cdd:COG1196   647 REVTLEGEGGSAGGSLTGGSRRELLAALLEAEA-----------ELEELAERLAEEELELEEALLAEEEEERELAEAEEE 715
                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 554506543 1167 cfsELENSEDTRTESWDLKSQISQLREQLTVLRADCDRASERKQDLLFDISVLKKKLKMLER 1228
Cdd:COG1196   716 ---RLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLER 774
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1435-1735 7.61e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 7.61e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1435 LQQEATIAELELEKQKLQELTRNLRERVTALvrqKDAPSQGQKE-EELKAMMQDLQITCGEMQRKVELLRYESEKLQEEN 1513
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEKALAEL---RKELEELEEElEQLRKELEELSRQISALRKDLARLEAEVEQLEERI 749
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1514 SILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQ-------EKASIQTMVEKLKKQVSDLKIKNQQLDSENIEL 1586
Cdd:TIGR02168  750 AQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAqieqlkeELKALREALDELRAELTLLNEEAANLRERLESL 829
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1587 SQKNSQNKEELKTLNQRLAEMLCQREEPGACTSEKWEQENAsLKEELDHY---KVQTSTLVSSLEAELSEVKLQTHVMEQ 1663
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE-LESELEALlneRASLEEALALLRSELEELSEELRELES 908
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 554506543  1664 ENLLLKDELERLKQLhrcpdLSDFQQKMSS----ILSYNEKLLKEKEVLSEELKSCADKL-AESSLLEHRIATMKQE 1735
Cdd:TIGR02168  909 KRSELRRELEELREK-----LAQLELRLEGlevrIDNLQERLSEEYSLTLEEAEALENKIeDDEEEARRRLKRLENK 980
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
697-1607 1.55e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.62  E-value: 1.55e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   697 HEEEKRQLQMAfdEEKAQLQEELRQEHERELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALe 776
Cdd:TIGR02168  195 LNELERQLKSL--ERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEE- 271
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   777 keelreelsehHRRELQEGREEMET------ECNRRVSQIEAQCQADCEKVtEHCEQTLQSLEVRHRQELRDLLDQhLEE 850
Cdd:TIGR02168  272 -----------LRLEVSELEEEIEElqkelyALANEISRLEQQKQILRERL-ANLERQLEELEAQLEELESKLDEL-AEE 338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   851 RSQWEFEKDELTQECTDAQEQLKEAlqrerataAAMKQEQEILERTYKDRLNILSTERKQLLQDLKDLQNasesQHGLLS 930
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEEL--------EAELEELESRLEELEEQLETLRSKVAQLELQIASLNN----EIERLE 406
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   931 GQILELKRSQERELRDQGQALcqtgvsEQLASQQLERLRVEHEQERREMTGKLAALEsAHRASLERADQEKAEMSTEIcr 1010
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELL------KKLEEAELKELQAELEELEEELEELQEELE-RLEEALEELREELEEAEQAL-- 477
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1011 lqntvkdmqqaasllmlqggcQATAGEEAEGDGAMSLLQQGEQLLEENGDvlislqrahehAVKENAKMATEISRLQQRL 1090
Cdd:TIGR02168  478 ---------------------DAAERELAQLQARLDSLERLQENLEGFSE-----------GVKALLKNQSGLSGILGVL 525
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1091 KKL---EPG--SVISSCLEEGTSEISGSSREQVEPI---MKQGPATKHFLSDLGDHEARDLASTGTSSVQRQECktease 1162
Cdd:TIGR02168  526 SELisvDEGyeAAIEAALGGRLQAVVVENLNAAKKAiafLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEG------ 599
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1163 aSLDCFSELENSEDtrteswDLKSQISQLREQLTVLrADCDRASE--RKQDLLFDISVLKKKLkmlerlpeASSRYKVLY 1240
Cdd:TIGR02168  600 -FLGVAKDLVKFDP------KLRKALSYLLGGVLVV-DDLDNALElaKKLRPGYRIVTLDGDL--------VRPGGVITG 663
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1241 EDAARENSCLqeelrlvetryeesldsnkELTAEVYRLQDEMKKMEEvmeTFLSLEKSYDEVKVENEELRALVLRLQGKM 1320
Cdd:TIGR02168  664 GSAKTNSSIL-------------------ERRREIEELEEKIEELEE---KIAELEKALAELRKELEELEEELEQLRKEL 721
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1321 EKVLGRAALQGDSYALWEAPSENLEvasdEKMLELRQTPKECTPKVVSMHHIIEECTQETQCCEQGSTKLLARIKAHEIA 1400
Cdd:TIGR02168  722 EELSRQISALRKDLARLEAEVEQLE----ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE 797
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1401 WFhraikthpekpsaqnrvipEGSAALLGLQDKHLQQEATIAELELEKQKLQELTRNLRERVTALVRQKDAPSqgQKEEE 1480
Cdd:TIGR02168  798 LK-------------------ALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS--EDIES 856
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1481 LKAMMQDLQITCGEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQT 1560
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEV 936
                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*...
gi 554506543  1561 MVEKLKKQVSDLKIKNQQLDSENIELSQKNSQN-KEELKTLNQRLAEM 1607
Cdd:TIGR02168  937 RIDNLQERLSEEYSLTLEEAEALENKIEDDEEEaRRRLKRLENKIKEL 984
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
1436-1805 6.48e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 64.27  E-value: 6.48e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1436 QQEATIAELELEKQKLQELTRNLRERVTALVRQKDapsqgQKEEELkamMQDLQITCGEMQRKVELLRYESEKLQEENSI 1515
Cdd:TIGR04523  268 QLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNN-----QKEQDW---NKELKSELKNQEKKLEEIQNQISQNNKIISQ 339
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1516 LRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQTMVEKLKKQVSDLKIKNQQLDSENIELSQKNSQNKE 1595
Cdd:TIGR04523  340 LNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQ 419
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1596 ELKTLNQRLAEMLCQREEPGAcTSEKWEQENASLK---EELDHYKVQTSTLVSSLEAELSEVKLQTHVMEQENLLLKDEL 1672
Cdd:TIGR04523  420 EKELLEKEIERLKETIIKNNS-EIKDLTNQDSVKEliiKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKEL 498
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1673 ERLKQLHRCPD--LSDFQQKMSSILSYNEKLLKEKEVLSEELKSCADKLAE------SSLLE-------HRIATMKQEQT 1737
Cdd:TIGR04523  499 KKLNEEKKELEekVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKddfelkKENLEkeideknKEIEELKQTQK 578
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1738 A--------------WEEQSESLKSQLAVSQAKVQNLEDVLQNVNLQMAEIESDLQVTRQEKEALKQEVMSLHRQLQNAI 1803
Cdd:TIGR04523  579 SlkkkqeekqelidqKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIR 658

                   ..
gi 554506543  1804 DK 1805
Cdd:TIGR04523  659 NK 660
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
355-888 7.11e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.55  E-value: 7.11e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  355 NGIHQAALasfKA-EIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMAS-----EVDDHHAAIERRNEyNLRKLDEEY-- 426
Cdd:COG4913   238 ERAHEALE---DArEQIELLEPIRELAERYAAARERLAELEYLRAALRLwfaqrRLELLEAELEELRA-ELARLEAELer 313
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  427 -KERIAALKNELRQEREQMLQQVGKQRVELEQEIQKAKTEENYIRDRLALSLKENNRLETELLENAEKLAEYESLTQKLQ 505
Cdd:COG4913   314 lEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALL 393
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  506 RSLENVLAEkfgdldpssaefflQEERLAQMRNEYEQqcrlLQDQVDELQSELEEYQAQG-----RVLRlpLKNSLSEEL 580
Cdd:COG4913   394 EALEEELEA--------------LEEALAEAEAALRD----LRRELRELEAEIASLERRKsnipaRLLA--LRDALAEAL 453
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  581 dghsgGIEPDQGPgseecnplnmsIEAELVieQMKEQHH-------RDLCHLRLEL------EDKVRHY------EKQLD 641
Cdd:COG4913   454 -----GLDEAELP-----------FVGELI--EVRPEEErwrgaieRVLGGFALTLlvppehYAAALRWvnrlhlRGRLV 515
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  642 DTRVASEQEQAAMKQKYEQG-VHTLEKRVSELRSEIADLEGQA-----------------AVLREAHHKAS-CRHE---- 698
Cdd:COG4913   516 YERVRTGLPDPERPRLDPDSlAGKLDFKPHPFRAWLEAELGRRfdyvcvdspeelrrhprAITRAGQVKGNgTRHEkddr 595
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  699 -EEKRQLQMAFD---------EEKAQLQEELR--QEHERELQARLQQAAESfRQEREGLAQAAWTEEKVRGLEQSY---Q 763
Cdd:COG4913   596 rRIRSRYVLGFDnraklaaleAELAELEEELAeaEERLEALEAELDALQER-REALQRLAEYSWDEIDVASAEREIaelE 674
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  764 EQLLSLEEkhALEKEELREELSEHHRRELQEGREEMEtECNRRVSQIEAQcQADCEKVTEHCEQTLQSLEVRHRQELRDL 843
Cdd:COG4913   675 AELERLDA--SSDDLAALEEQLEELEAELEELEEELD-ELKGEIGRLEKE-LEQAEEELDELQDRLEAAEDLARLELRAL 750
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*.
gi 554506543  844 LDQHLEERSQWEFEKdELTQECTDAQEQLKEALQR-ERATAAAMKQ 888
Cdd:COG4913   751 LEERFAAALGDAVER-ELRENLEERIDALRARLNRaEEELERAMRA 795
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
373-1094 2.12e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.15  E-value: 2.12e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   373 LERVDQVVRE----KEKLRSDLDKAEKLKSLMASE--------VDDHHAAIERRNEYNLRKldEEYKERIAALKNELrQE 440
Cdd:TIGR02168  188 LDRLEDILNElerqLKSLERQAEKAERYKELKAELrelelallVLRLEELREELEELQEEL--KEAEEELEELTAEL-QE 264
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   441 REQMLQQVGKQRVELEQEIQKAKTEEN--------------YIRDRLALSLKENNRLETELLENAEKLAEYESLTQKLQR 506
Cdd:TIGR02168  265 LEEKLEELRLEVSELEEEIEELQKELYalaneisrleqqkqILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   507 ---SLENVLAEKFGDLDPSSAEFFLQEERLAQMRNEYEQQCR---LLQDQVDELQSELEEYQAQGRVLRLPLKNSLSEEL 580
Cdd:TIGR02168  345 kleELKEELESLEAELEELEAELEELESRLEELEEQLETLRSkvaQLELQIASLNNEIERLEARLERLEDRRERLQQEIE 424
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   581 DGHSGGIEPDQGPGSEECNPLNMSIEAELVIEQMKEQHHRDLCHLRLELEDKVRHYEKQLD--DTRVASEQEQAAMKQKY 658
Cdd:TIGR02168  425 ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAqlQARLDSLERLQENLEGF 504
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   659 EQGVHTLEK----------RVSELRSEIADLE-GQAAVLREAHHKASCRHEEEKRQLQmAFDEEKAQLQE---ELRQEHE 724
Cdd:TIGR02168  505 SEGVKALLKnqsglsgilgVLSELISVDEGYEaAIEAALGGRLQAVVVENLNAAKKAI-AFLKQNELGRVtflPLDSIKG 583
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   725 RELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQ----------SYQEQLLSLEEKHALEK----------------- 777
Cdd:TIGR02168  584 TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvlvvdDLDNALELAKKLRPGYRivtldgdlvrpggvitg 663
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   778 -EELREELSEHHRRELQEGREEME------TECNRRVSQIEAQcQADCEKVTEHCEQTLQSLEVRHRqELRDLLDQHLEE 850
Cdd:TIGR02168  664 gSAKTNSSILERRREIEELEEKIEeleekiAELEKALAELRKE-LEELEEELEQLRKELEELSRQIS-ALRKDLARLEAE 741
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   851 RSQWEFEKDELTQECTDAQEQLKEALQR---ERATAAAMKQEQEILERTYKDRLNILSTERKQLLQDLKDLQNASESQHG 927
Cdd:TIGR02168  742 VEQLEERIAQLSKELTELEAEIEELEERleeAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN 821
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   928 LLSG--QILELKRSQERELRDQGQALCQTGVSEQLASQQLERLRVEHEQERREMTGKLAALESAHRAsLERADQEKAEMS 1005
Cdd:TIGR02168  822 LRERleSLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEA-LALLRSELEELS 900
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1006 TEICRLQNTVKDMQQAASLLMLQGGCQATAGEEAEGDgamsLLQQGEQLLEENGDVLislqrahEHAVKENAKMATEISR 1085
Cdd:TIGR02168  901 EELRELESKRSELRRELEELREKLAQLELRLEGLEVR----IDNLQERLSEEYSLTL-------EEAEALENKIEDDEEE 969

                   ....*....
gi 554506543  1086 LQQRLKKLE 1094
Cdd:TIGR02168  970 ARRRLKRLE 978
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
869-1613 3.96e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.00  E-value: 3.96e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   869 QEQLKEALQRERATAAAMKQEQEILERTYKdRLNILSTERKQLlQDLKDLQNA-SESQHGLLSGQILELKRSQER--ELR 945
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLEDILNELER-QLKSLERQAEKA-ERYKELKAElRELELALLVLRLEELREELEElqEEL 248
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   946 DQGQALCQTGVSE-QLASQQLERLRVEHEQERREM----------TGKLAALES---AHRASLERADQEKAEMSTEICRL 1011
Cdd:TIGR02168  249 KEAEEELEELTAElQELEEKLEELRLEVSELEEEIeelqkelyalANEISRLEQqkqILRERLANLERQLEELEAQLEEL 328
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1012 QNTVKDMQQAASLLMLQGGCQAT--AGEEAEGDGAMSLLQQGEQLLEENGDVLISLQRAHEHAVKENAKMATEISRLQQR 1089
Cdd:TIGR02168  329 ESKLDELAEELAELEEKLEELKEelESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEAR 408
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1090 LKKLEpgsvisSCLEEGTSEISGSSREQVEPIMKQGPATkhflSDLGDHEARDLASTGTSSVQRQECKTEASEASldcfs 1169
Cdd:TIGR02168  409 LERLE------DRRERLQQEIEELLKKLEEAELKELQAE----LEELEEELEELQEELERLEEALEELREELEEA----- 473
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1170 elensedtRTESWDLKSQISQLREQLTVLRADCDRASERKQDLLFdisVLKKKLKMLERLPEASSRYKVLYEDAARENSC 1249
Cdd:TIGR02168  474 --------EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKA---LLKNQSGLSGILGVLSELISVDEGYEAAIEAA 542
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1250 LQEELRLVETRYEES--------------------LDSNKELTAEVYRLQdEMKKMEEVMETFLSLEKSYDEVKVENEEL 1309
Cdd:TIGR02168  543 LGGRLQAVVVENLNAakkaiaflkqnelgrvtflpLDSIKGTEIQGNDRE-ILKNIEGFLGVAKDLVKFDPKLRKALSYL 621
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1310 RALV---------LRLQGKMEKVLGRAALQGD------SYALWEAPSENLEVASDEKMLELRQTPKECTPKVVSMHHIIE 1374
Cdd:TIGR02168  622 LGGVlvvddldnaLELAKKLRPGYRIVTLDGDlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALA 701
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1375 ECTQETQCCEQGSTKLLARIKAHE---------IAWFHRAIKTHPEKPSAQNRVIPEGSAALLGLQDKHLQQEATIAELE 1445
Cdd:TIGR02168  702 ELRKELEELEEELEQLRKELEELSrqisalrkdLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE 781
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1446 LEKQKLQELTRNLRERVTALVRQKDapsqgqkeeELKAMMQDLQITCGEMQRKVELLRYESEKLQEENSILRNEITTLNE 1525
Cdd:TIGR02168  782 AEIEELEAQIEQLKEELKALREALD---------ELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE 852
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1526 EDSISNLKLEELNGSQEELWQKIETIEQEKASIQTMVEKLKKQVSDLKIKNQQLDSENIELSQKNSQNKEELKTLNQRLA 1605
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932

                   ....*...
gi 554506543  1606 EMLCQREE 1613
Cdd:TIGR02168  933 GLEVRIDN 940
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
1476-1816 5.11e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.57  E-value: 5.11e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1476 QKEEELKAMMQDLQITCGEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEK 1555
Cdd:TIGR04523  398 SKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSI 477
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1556 ASIQTMVEKLKKQvsdLKIKNQQLDseniELSQKNSQNKEELKTLNQRLAEMLCQREEPGACTSEKwEQENASLKEELDh 1635
Cdd:TIGR04523  478 NKIKQNLEQKQKE---LKSKEKELK----KLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEK-ESKISDLEDELN- 548
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1636 ykvqtstlvsSLEAELSEVKLQTHVMEQEnlllkdelERLKQLHrcpdlsdfqQKMSSILSYNEKLLKEKEVLSEELKSC 1715
Cdd:TIGR04523  549 ----------KDDFELKKENLEKEIDEKN--------KEIEELK---------QTQKSLKKKQEEKQELIDQKEKEKKDL 601
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1716 ADKLAEsslLEHRIATMKQEQTAWEEQSESLKSQLAVSQAKVQNLEDVLQNVNLQMAEIESDLQVTRQEKEALKQEVMSL 1795
Cdd:TIGR04523  602 IKEIEE---KEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDI 678
                          330       340
                   ....*....|....*....|.
gi 554506543  1796 hrqlqNAIDKDWVSETAPHLS 1816
Cdd:TIGR04523  679 -----IELMKDWLKELSLHYK 694
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
359-1011 2.51e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 2.51e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   359 QAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVddhhaaieRRNEYNLRKLDEEYKERIAALKNELR 438
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI--------ERLEARLERLEDRRERLQQEIEELLK 428
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   439 QEREQMLQQVGKQRVELEQEIQKAKTEENYIRDRLALSLKENNRLETELLENAEKLAEYESLTQKLQRSLENVL------ 512
Cdd:TIGR02168  429 KLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegv 508
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   513 ------AEKFGDLDPSSAEFFlqeerlaQMRNEYEQ------QCRLLQDQVDELQSELEEYQAQ-----GRVLRLPLKNS 575
Cdd:TIGR02168  509 kallknQSGLSGILGVLSELI-------SVDEGYEAaieaalGGRLQAVVVENLNAAKKAIAFLkqnelGRVTFLPLDSI 581
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   576 LSEELDGHSGGIEPDQGPGSEECNPL-NMSIEAELVIEQMkeqhhrdLCHLR--------LELEDKVRHYEK--QLDDTR 644
Cdd:TIGR02168  582 KGTEIQGNDREILKNIEGFLGVAKDLvKFDPKLRKALSYL-------LGGVLvvddldnaLELAKKLRPGYRivTLDGDL 654
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   645 VASEQEQAAMKQKYEQGVHTLEKRVSELRSEIADLEGQAavlreahhkascrheeekRQLQMAFDEEKAQLQEelRQEHE 724
Cdd:TIGR02168  655 VRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKI------------------AELEKALAELRKELEE--LEEEL 714
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   725 RELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALEKEELREElsehhRRELQEGREEMETEcN 804
Cdd:TIGR02168  715 EQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA-----EEELAEAEAEIEEL-E 788
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   805 RRVSQIEAQCQADcekvtehcEQTLQSLEVRHrQELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRERATAA 884
Cdd:TIGR02168  789 AQIEQLKEELKAL--------REALDELRAEL-TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA 859
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   885 AMKQEQEiLERTYKDRLNILSTERKQLLQDLK----DLQNASESQHGlLSGQILELKRsQERELRDQ-GQALCQTGVSEQ 959
Cdd:TIGR02168  860 EIEELEE-LIEELESELEALLNERASLEEALAllrsELEELSEELRE-LESKRSELRR-ELEELREKlAQLELRLEGLEV 936
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|..
gi 554506543   960 LASQQLERLRVEHEQERREMtgklAALESAHRASLERADQEKAEMSTEICRL 1011
Cdd:TIGR02168  937 RIDNLQERLSEEYSLTLEEA----EALENKIEDDEEEARRRLKRLENKIKEL 984
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
1010-1789 3.11e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.98  E-value: 3.11e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1010 RLQNTVKDMQQAASLlmlQGGCQATAGEEAEGDGAMSLLQQGeqLLEENGDVLISLQRAHEHAVKENAKMATEISRlqqr 1089
Cdd:pfam15921  146 QLQNTVHELEAAKCL---KEDMLEDSNTQIEQLRKMMLSHEG--VLQEIRSILVDFEEASGKKIYEHDSMSTMHFR---- 216
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1090 lkklEPGSVISSCLEEGTSEISgSSREQVEPIMKQGPATKHflsdlgdhEARDLASTgtsSVQRQECKTEA--SEASLDC 1167
Cdd:pfam15921  217 ----SLGSAISKILRELDTEIS-YLKGRIFPVEDQLEALKS--------ESQNKIEL---LLQQHQDRIEQliSEHEVEI 280
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1168 FSELENSEDTRTESWDLKSQISQLREQLtvlRADCDRASERKQDLLFDISVLKKKLKMLERLpeassrykvlYEDAAREn 1247
Cdd:pfam15921  281 TGLTEKASSARSQANSIQSQLEIIQEQA---RNQNSMYMRQLSDLESTVSQLRSELREAKRM----------YEDKIEE- 346
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1248 scLQEELRLVETRYEESLDSNKELTAEVYRLQDEMKKMEEVM---ETFLSLEKS----------------------YDEV 1302
Cdd:pfam15921  347 --LEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLhkrEKELSLEKEqnkrlwdrdtgnsitidhlrreLDDR 424
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1303 KVENEELRALVLRL----QGKMEKVLgrAALQGDSYALWEAPSENLEVASDEKMLelRQTPKECTPKVVSMhhiieectq 1378
Cdd:pfam15921  425 NMEVQRLEALLKAMksecQGQMERQM--AAIQGKNESLEKVSSLTAQLESTKEML--RKVVEELTAKKMTL--------- 491
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1379 etQCCEQGSTKLLARIKAHEiawfhRAIK-THPEKPSAQNRVipegSAALLGLQD--------KHLQQEATIAELEL-EK 1448
Cdd:pfam15921  492 --ESSERTVSDLTASLQEKE-----RAIEaTNAEITKLRSRV----DLKLQELQHlknegdhlRNVQTECEALKLQMaEK 560
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1449 QKLQELTRNLRERVTALVrqkdapsqGQKEEELKAMmqdlQITCGEMQRKVELLRYESEKLQEENSILRNEITTLneEDS 1528
Cdd:pfam15921  561 DKVIEILRQQIENMTQLV--------GQHGRTAGAM----QVEKAQLEKEINDRRLELQEFKILKDKKDAKIREL--EAR 626
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1529 ISNLKLEEL---NGSQEELwQKIETIEQEKASIQTMVEKLKKQVSDLkiknqqldSENIELSQKNSQNK-EELKTlnqrl 1604
Cdd:pfam15921  627 VSDLELEKVklvNAGSERL-RAVKDIKQERDQLLNEVKTSRNELNSL--------SEDYEVLKRNFRNKsEEMET----- 692
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1605 aemlcqreepgacTSEKWEQENASLKEELDhykvQTSTLVSSLEAELSEVKLQTHVMEQENLLLKDELERLkqlhrcpdl 1684
Cdd:pfam15921  693 -------------TTNKLKMQLKSAQSELE----QTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDAL--------- 746
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1685 sdfQQKMSSILSYNEKLLKEKEVLSEElkscadklaeSSLLEHRIATMKQEQTAWEEQSESLKSQLAVSQAKVQNLEDVL 1764
Cdd:pfam15921  747 ---QSKIQFLEEAMTNANKEKHFLKEE----------KNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVAL 813
                          810       820
                   ....*....|....*....|....*
gi 554506543  1765 QNVNLQMAEIESDLQvtRQEKEALK 1789
Cdd:pfam15921  814 DKASLQFAECQDIIQ--RQEQESVR 836
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1449-1797 3.55e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 3.55e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1449 QKLQELTRNLRERVTALVRQKdapSQGQKEEELKAMMQDLQITC-----GEMQRKVELLRYESEKLQEENSILRNEITTL 1523
Cdd:TIGR02168  189 DRLEDILNELERQLKSLERQA---EKAERYKELKAELRELELALlvlrlEELREELEELQEELKEAEEELEELTAELQEL 265
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1524 NEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQTMVEKLKKQVSDLKIKNQQLDSENIELSQKNSQNKEELKTLNQR 1603
Cdd:TIGR02168  266 EEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEK 345
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1604 LAEmlcqreepgacTSEKWEQENASLKEELDHYKVQTSTLvSSLEAELSEVKLQTHVMEQENLLLKDELERLKqlhrcpd 1683
Cdd:TIGR02168  346 LEE-----------LKEELESLEAELEELEAELEELESRL-EELEEQLETLRSKVAQLELQIASLNNEIERLE------- 406
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1684 lsdfqQKMSSILSYNEKLLKEKEVLSEELKSCADKLAESSLLEHR--IATMKQEQTAWEEQSESLKSQLAVSQAKVQNLE 1761
Cdd:TIGR02168  407 -----ARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEeeLEELQEELERLEEALEELREELEEAEQALDAAE 481
                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 554506543  1762 DVLQNVNLQMAEIESDLQVTRQEKEALKQEVMSLHR 1797
Cdd:TIGR02168  482 RELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG 517
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
320-911 3.80e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 3.80e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   320 ENSQEILKALDFSLDGNINLTELTLALENELLVTKNGIHQAALASFKA---EIRHLLERVDQVVREKEKLRSDLDKAEKL 396
Cdd:TIGR02168  329 ESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEleeQLETLRSKVAQLELQIASLNNEIERLEAR 408
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   397 KSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRQ------EREQMLQQVGKQRVELEQEIQKAKTEENYIR 470
Cdd:TIGR02168  409 LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEElqeeleRLEEALEELREELEEAEQALDAAERELAQLQ 488
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   471 DRLALSLKENNRLET------ELLENAEKLAEYESL-------TQKLQRSLENVLAEKFGDLDPSSAEF------FLQEE 531
Cdd:TIGR02168  489 ARLDSLERLQENLEGfsegvkALLKNQSGLSGILGVlselisvDEGYEAAIEAALGGRLQAVVVENLNAakkaiaFLKQN 568
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   532 RL------------AQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVL----------------RLPLKNSLSEE---- 579
Cdd:TIGR02168  569 ELgrvtflpldsikGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvvddldnALELAKKLRPGyriv 648
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   580 -LDGH---SGGIEpDQGPGSEECNPLNMSIEAELVIEQMKEQHH--RDLCHLRLELEDKVRHYEKQLDDTRVASEQ---- 649
Cdd:TIGR02168  649 tLDGDlvrPGGVI-TGGSAKTNSSILERRREIEELEEKIEELEEkiAELEKALAELRKELEELEEELEQLRKELEElsrq 727
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   650 --EQAAMKQKYEQGVHTLEKRVSELRSEIADLEGQAAVLREAHHKASCRHEEEKRQLQmAFDEEKAQLQEELRQEHER-- 725
Cdd:TIGR02168  728 isALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE-ELEAQIEQLKEELKALREAld 806
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   726 ELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQLLSLEEkhalekeelREELSEHHRRELQEGREEMETECNr 805
Cdd:TIGR02168  807 ELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE---------DIESLAAEIEELEELIEELESELE- 876
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   806 RVSQIEAQCQADCEKVTEHCEQ---TLQSLEvRHRQELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRERAT 882
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEElseELRELE-SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEE 955
                          650       660
                   ....*....|....*....|....*....
gi 554506543   883 AAAMKQEQEILERTYKDRLNILSTERKQL 911
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
404-1291 5.02e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.53  E-value: 5.02e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   404 VDDHHAAIERrneyNLRKLDEEYK--ERIAALKNELRQEREQML----QQVGKQRVELEQEIQKAKTEENYIRDRLALSL 477
Cdd:TIGR02168  191 LEDILNELER----QLKSLERQAEkaERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTAELQELE 266
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   478 KENNRLETELLENAEKLAEYESLTQKLQRSLENVLAEKFgdldpssaeffLQEERLAQMRNEYEQqcrlLQDQVDELQSE 557
Cdd:TIGR02168  267 EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQ-----------ILRERLANLERQLEE----LEAQLEELESK 331
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   558 LEEYQAQgrvlrlplKNSLSEELDghsggiepdqgpgseecnplnmsiEAELVIEQMKEQHHrdlchlrlELEDKVRHYE 637
Cdd:TIGR02168  332 LDELAEE--------LAELEEKLE------------------------ELKEELESLEAELE--------ELEAELEELE 371
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   638 KQLDDTRVASEQEQAAMKQKYEQgVHTLEKRVSELRSEIADLEGQAAVLREAHHKASCRHEEEKRQLQMAFDEEKAQLQE 717
Cdd:TIGR02168  372 SRLEELEEQLETLRSKVAQLELQ-IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELE 450
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   718 ELRQEHEReLQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALEKEELREELSEHHRR----ELQ 793
Cdd:TIGR02168  451 ELQEELER-LEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgvlsELI 529
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   794 EGREEMETEC----------------NRRVSQIEAQCQADCEKVT-----EHCEQTLQSLEVRHRQELRDLLDQHLEERS 852
Cdd:TIGR02168  530 SVDEGYEAAIeaalggrlqavvvenlNAAKKAIAFLKQNELGRVTflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVK 609
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   853 QWEFEKDEL---------TQECTDAQEQLKEALQRER--------------ATAAAMKQEQEILERtyKDRLNILSTERK 909
Cdd:TIGR02168  610 FDPKLRKALsyllggvlvVDDLDNALELAKKLRPGYRivtldgdlvrpggvITGGSAKTNSSILER--RREIEELEEKIE 687
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   910 QLLQDLKDLQNASESQHGLLSG--QILELKRSQERELRDQGQALCQTGVSEQLASQQLERLRVEHEQERREMTGKLAALE 987
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEEleEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   988 SAhrasLERADQEKAEMSTEICRLQNTVKDMQQAASLLMLQGgcQATAGEEAEGDGAMSLLQQGEQLLEENgdvLISLQR 1067
Cdd:TIGR02168  768 ER----LEEAEEELAEAEAEIEELEAQIEQLKEELKALREAL--DELRAELTLLNEEAANLRERLESLERR---IAATER 838
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1068 AHEHAVKENAKMATEISRLQQRLKKLE-PGSVISSCLEEGTSEISGSSREQvepimkqgpatkhflsdlgdHEARDLAST 1146
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEeLIEELESELEALLNERASLEEAL--------------------ALLRSELEE 898
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1147 GTSSVQRQECKTEASEASLDCFSELENSEDTRTESwdLKSQISQLREQLTVL-RADCDRASERKQDLLFDISVLKKKLKM 1225
Cdd:TIGR02168  899 LSEELRELESKRSELRRELEELREKLAQLELRLEG--LEVRIDNLQERLSEEySLTLEEAEALENKIEDDEEEARRRLKR 976
                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 554506543  1226 LERLPEASSRYKVLYEdaarensclqEELRLVETRYEEsLDSNKE-LTAEVYRLQDEMKKMEEVMET 1291
Cdd:TIGR02168  977 LENKIKELGPVNLAAI----------EEYEELKERYDF-LTAQKEdLTEAKETLEEAIEEIDREARE 1032
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
360-689 5.88e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.16  E-value: 5.88e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   360 AALASFKAEIRHLLERVDQVVREKEKLRSDLDkaEKLKSLMASEVDDHHAaiERRNEYNLRKLDEEYKERIAAlKNELRQ 439
Cdd:TIGR02169  163 AGVAEFDRKKEKALEELEEVEENIERLDLIID--EKRQQLERLRREREKA--ERYQALLKEKREYEGYELLKE-KEALER 237
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   440 EREQMLQQVGKQRVELEQ---EIQKAKTEENYIRDRLA-LSLKENNRLETELLENAEKLAEYESLTQKLQRSLEnVLAEK 515
Cdd:TIGR02169  238 QKEAIERQLASLEEELEKlteEISELEKRLEEIEQLLEeLNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIA-EKERE 316
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   516 FGDLDPSSAEFFLQ----EERLAQMRNEYEQQCRL----------LQDQVDELQSELEEYQAQGRVLRLPLKnSLSEELD 581
Cdd:TIGR02169  317 LEDAEERLAKLEAEidklLAEIEELEREIEEERKRrdklteeyaeLKEELEDLRAELEEVDKEFAETRDELK-DYREKLE 395
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   582 GHSGGIEPDQGpgsEECNPLNMSIEAELVIEQMK------EQHHRDLCHLRLELEDKVRHYE---KQLDDTRVASEQEQA 652
Cdd:TIGR02169  396 KLKREINELKR---ELDRLQEELQRLSEELADLNaaiagiEAKINELEEEKEDKALEIKKQEwklEQLAADLSKYEQELY 472
                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 554506543   653 AMKQKYEQgvhtLEKRVSELRSEIADLEGQAAVLREA 689
Cdd:TIGR02169  473 DLKEEYDR----VEKELSKLQRELAEAEAQARASEER 505
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
1433-1766 1.36e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 1.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1433 KHLQQEATIAElelekqKLQELTRNLRERvtalvrqkdapsqgqKEEELKAMMQDLQITCGEMQRKVELLRYESEKLQEE 1512
Cdd:COG1196   203 EPLERQAEKAE------RYRELKEELKEL---------------EAELLLLKLRELEAELEELEAELEELEAELEELEAE 261
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1513 NSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASiqtmvekLKKQVSDLKIKNQQLDSENIELSQKNSQ 1592
Cdd:COG1196   262 LAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIAR-------LEERRRELEERLEELEEELAELEEELEE 334
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1593 NKEELKTLNQRLAEMLCQREEPGAC---TSEKWEQENASLKEELDHYKVQTSTLVSSLEAELSEVKLQTHVMEQENLLLK 1669
Cdd:COG1196   335 LEEELEELEEELEEAEEELEEAEAElaeAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1670 DELERLKQLhrcpdlsdfQQKMSSILSYNEKLLKEKEVLSEELKSCADKLAESSLLEHRIATMKQEQTAWEEQSESLKSQ 1749
Cdd:COG1196   415 RLERLEEEL---------EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485
                         330
                  ....*....|....*..
gi 554506543 1750 LAVSQAKVQNLEDVLQN 1766
Cdd:COG1196   486 LAEAAARLLLLLEAEAD 502
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
606-1094 1.36e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.85  E-value: 1.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  606 EAELVIEQMKE--QHHRDLCHLR------LELEDKVRHYEKQLDDTRVASEQEQAAMKQKYEQGVHTLEKRVSELRSEIA 677
Cdd:COG4913   226 AADALVEHFDDleRAHEALEDAReqiellEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELA 305
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  678 DLEGQAAVLREAHHKASCRHEEEKRQLQMAFDEEKAQLQEELRQEhERELQaRLQQAAESFRQEREGL-AQAAWTEEKVR 756
Cdd:COG4913   306 RLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERL-ERELE-ERERRRARLEALLAALgLPLPASAEEFA 383
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  757 GLEQSYQEQLLSLEEKHALEKEELREELSEHH--RRELQEGREEMETECNRRVS----------QIEAQCQAD------- 817
Cdd:COG4913   384 ALRAEAAALLEALEEELEALEEALAEAEAALRdlRRELRELEAEIASLERRKSNiparllalrdALAEALGLDeaelpfv 463
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  818 CE--KVTEHC-------EQTLQSL------EVRHRQELRDLLDQ-HLEERSQWE-------------FEKDELTQE---- 864
Cdd:COG4913   464 GEliEVRPEEerwrgaiERVLGGFaltllvPPEHYAAALRWVNRlHLRGRLVYErvrtglpdperprLDPDSLAGKldfk 543
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  865 -------------------CTDAQEQLKealQRERA-TAAAM-KQEQEILE---RTYKDRLNILSTERKQLLQDLKDLQN 920
Cdd:COG4913   544 phpfrawleaelgrrfdyvCVDSPEELR---RHPRAiTRAGQvKGNGTRHEkddRRRIRSRYVLGFDNRAKLAALEAELA 620
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  921 ASESQHGLLSGQILELKRsQERELRDQGQAL--CQTGVSEQLASQQLERLRVEHEQERREMT---GKLAALES---AHRA 992
Cdd:COG4913   621 ELEEELAEAEERLEALEA-ELDALQERREALqrLAEYSWDEIDVASAEREIAELEAELERLDassDDLAALEEqleELEA 699
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  993 SLERADQEKAEMSTEICRLQNTVKDMQQaasllmLQGGCQATAgEEAEGDGAMSLLQQGEQLLEENgdvlisLQRAHEHA 1072
Cdd:COG4913   700 ELEELEEELDELKGEIGRLEKELEQAEE------ELDELQDRL-EAAEDLARLELRALLEERFAAA------LGDAVERE 766
                         570       580
                  ....*....|....*....|..
gi 554506543 1073 VKENakMATEISRLQQRLKKLE 1094
Cdd:COG4913   767 LREN--LEERIDALRARLNRAE 786
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
1498-1811 1.50e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.57  E-value: 1.50e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1498 KVELLRYESEKLQEENSI--LRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQTMVEKLKKQ------- 1568
Cdd:TIGR04523  123 EVELNKLEKQKKENKKNIdkFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKllklell 202
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1569 VSDLKIKNQ---QLDSENIELSQKNSQNKEELKTLNQRLAEM---LCQREEPGACTSEKWEQENASLKEELDHYKvQTST 1642
Cdd:TIGR04523  203 LSNLKKKIQknkSLESQISELKKQNNQLKDNIEKKQQEINEKtteISNTQTQLNQLKDEQNKIKKQLSEKQKELE-QNNK 281
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1643 LVSSLEAELSEVKLQTHVMEQE-----NLLLKDELERLKQLHRC--PDLSDFQQKMSSILSYNEKLLKEKEVLSEELKSC 1715
Cdd:TIGR04523  282 KIKELEKQLNQLKSEISDLNNQkeqdwNKELKSELKNQEKKLEEiqNQISQNNKIISQLNEQISQLKKELTNSESENSEK 361
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1716 ADKLAESsllEHRIATMKQEQTAWEEQSESLKSQLAVSQAKVQNLEDVLQNVNLQMAEIESDLQVTRQEKEALKQEVMSL 1795
Cdd:TIGR04523  362 QRELEEK---QNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKN 438
                          330
                   ....*....|....*.
gi 554506543  1796 HRQLQNAIDKDWVSET 1811
Cdd:TIGR04523  439 NSEIKDLTNQDSVKEL 454
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1422-1678 2.41e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 56.22  E-value: 2.41e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1422 EGSAALLGLQDKHLQQEATIAELELEKQKLQELTRNLRERVTALVRQKDApsQGQKEEELKAMMQDLQITCGEMQRKVEL 1501
Cdd:TIGR02168  257 ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI--LRERLANLERQLEELEAQLEELESKLDE 334
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1502 LRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQTMVEKLKKQVSDLKIKNQQLDS 1581
Cdd:TIGR02168  335 LAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLED 414
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1582 ENIELSQKNSQNKEELKTLNQRLAEMLCQREEPGACTSEKWEQENASLKEELDHYKVQTSTLVSSLEAELSEVKLQTHVM 1661
Cdd:TIGR02168  415 RRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL 494
                          250
                   ....*....|....*..
gi 554506543  1662 EQENLLLKDELERLKQL 1678
Cdd:TIGR02168  495 ERLQENLEGFSEGVKAL 511
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
650-999 2.44e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 55.90  E-value: 2.44e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   650 EQAAMKQKYEQGVHTLEKRVSELRSEIA---DLEGQAAVLREAHHKA--------SCRHEEEKRQLQMAFDEEKAQLQEE 718
Cdd:pfam17380  297 EQERLRQEKEEKAREVERRRKLEEAEKArqaEMDRQAAIYAEQERMAmerereleRIRQEERKRELERIRQEEIAMEISR 376
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   719 LRqEHEReLQARLQQAAESFRQEREGlaqaawtEEKVRGLEQSYQEQLlsleekhalekeelreelsEHHRRELQEGREE 798
Cdd:pfam17380  377 MR-ELER-LQMERQQKNERVRQELEA-------ARKVKILEEERQRKI-------------------QQQKVEMEQIRAE 428
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   799 METECNRRVSQIEAQCQADCEKVTEhceqtlqslEVRHRQELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQR 878
Cdd:pfam17380  429 QEEARQREVRRLEEERAREMERVRL---------EEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEK 499
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   879 ERAtaaamKQEQEILERTYKdrlnilsteRKQLLQDLKDLQNASESQhgllsgqilELKRSQERELRDQGQALCQTGVSE 958
Cdd:pfam17380  500 ELE-----ERKQAMIEEERK---------RKLLEKEMEERQKAIYEE---------ERRREAEEERRKQQEMEERRRIQE 556
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 554506543   959 QLASQQLERLRVEHEQERREMTGKLAALESAhRASLERADQ 999
Cdd:pfam17380  557 QMRKATEERSRLEAMEREREMMRQIVESEKA-RAEYEATTP 596
PLN02939 PLN02939
transferase, transferring glycosyl groups
1462-1800 2.83e-07

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 56.06  E-value: 2.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1462 VTALVRQKDAPSQGQKEEELKAMMQDLQITCGEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQ 1541
Cdd:PLN02939   33 VSCRARRRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHNRASMQRDEAIAAID 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1542 EELWQKIETIEQEkASIQ-----TMVEKLKKQVSDL-KIKNQQLDSENIELSQKNSQNKEeLKTLNQRLAEMLCQRE--E 1613
Cdd:PLN02939  113 NEQQTNSKDGEQL-SDFQledlvGMIQNAEKNILLLnQARLQALEDLEKILTEKEALQGK-INILEMRLSETDARIKlaA 190
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1614 PGACTSEKWEQENASLKEELDHYKVQTSTLVSSLEAELSEVKLqthvmeqENLLLKDELERLKQlhrcpDLSDFQQKMSS 1693
Cdd:PLN02939  191 QEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKE-------ENMLLKDDIQFLKA-----ELIEVAETEER 258
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1694 ILsyneKLLKEKEVLSEELKSCADKLAESSLLEHRIATMKQEqtAWEEQSESLKSQLAVSQAKVQNLEDVL-QNVNL--Q 1770
Cdd:PLN02939  259 VF----KLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYD--CWWEKVENLQDLLDRATNQVEKAALVLdQNQDLrdK 332
                         330       340       350
                  ....*....|....*....|....*....|....*.
gi 554506543 1771 MAEIESDLQVTRQEK------EALKQEVMSLHRQLQ 1800
Cdd:PLN02939  333 VDKLEASLKEANVSKfssykvELLQQKLKLLEERLQ 368
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1438-1800 3.05e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.84  E-value: 3.05e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1438 EATIAELELEKQKLQELTRNLRERVTALVRQKDAPSQGQKEEELKAMMQDLQITcgEMQRKVELLRYESEKLQEENSILR 1517
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGY--ELLKEKEALERQKEAIERQLASLE 250
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1518 NEITTLNEEDSISNLKLEELNGSQEELWQKIETI-EQEKASIQTMVEKLKKQVSDLKiKNQQLDSENIELSQKNSQNKEE 1596
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLE-RSIAEKERELEDAEERLAKLEA 329
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1597 LKTLNQRLAEMLCQREEPGACTSEKWEQENASLKEELDhykvqtstlvsSLEAELSEVklqthvmEQENLLLKDELERLK 1676
Cdd:TIGR02169  330 EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELE-----------DLRAELEEV-------DKEFAETRDELKDYR 391
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1677 QlhrcpDLSDFQQKMSSILSYNEKLLKEKEVLSEELkscadklaesSLLEHRIATMKQEQTAWEEQSESLKSQLAVSQAK 1756
Cdd:TIGR02169  392 E-----KLEKLKREINELKRELDRLQEELQRLSEEL----------ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWK 456
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 554506543  1757 VQNLEDVLQNVNLQMAEIESDLQVTRQEKEALKQEVMSLHRQLQ 1800
Cdd:TIGR02169  457 LEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQAR 500
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
315-947 4.69e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.36  E-value: 4.69e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   315 QEEGIENSQEILKALDFSLDGNINLTELTLALENELLVTKNGIHQAALAsfKAEIRHLLERVDQVVREKEKLRSDLDKAE 394
Cdd:pfam02463  276 EEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK--KAEKELKKEKEEIEELEKELKELEIKREA 353
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   395 KLKSLMASEvddhhaAIERRNEYNLRKLDEEYKERIAALKNELRQEREQMlqqvgkqrvELEQEIQKAKTEENYIRDRLA 474
Cdd:pfam02463  354 EEEEEEELE------KLQEKLEQLEEELLAKKKLESERLSSAAKLKEEEL---------ELKSEEEKEAQLLLELARQLE 418
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   475 LSLKENNRLETELLENAEKLAEYESLTQKLQRSLENVLAEKFGDLDPSSAEFFLQEERLAQMRNEYEQQCRLLQDQVDEL 554
Cdd:pfam02463  419 DLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEER 498
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   555 QSELEEYQAQGRVLRLPLKNSLSEELDGHSGGIEpDQGPGSEECNPLNMSIEAELVIEQMKEQHHRDLCHLRLELEDKVR 634
Cdd:pfam02463  499 SQKESKARSGLKVLLALIKDGVGGRIISAHGRLG-DLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGA 577
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   635 HYEKQLDDTRVASEQEQAAMKQKYEQGVHTLEKRVSELRSEIA-------DLEGQAAVLREAHHKASCRHEEEKRQLQMA 707
Cdd:pfam02463  578 RKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKrakvvegILKDTELTKLKESAKAKESGLRKGVSLEEG 657
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   708 FDEEKAQLQEELRQEHERELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALEKEELREELSEH 787
Cdd:pfam02463  658 LAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEE 737
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   788 HRRELQEGREEMETECNRRVSQIEAQCQADCEKVTEHCEQTLQSLEVRHRQELRDLLDQHLEERSQWEFEKDELTQECTD 867
Cdd:pfam02463  738 LKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELL 817
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   868 AQEQLKEALQRERATAAAMKQEQEILERTYKDRLNILSTERKQLLQdLKDLQNASESQHGLLSGQILELKRSQERELRDQ 947
Cdd:pfam02463  818 EEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEI-TKEELLQELLLKEEELEEQKLKDELESKEEKEK 896
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
606-928 4.77e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.07  E-value: 4.77e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   606 EAELVIEQMKEQHHRdlchLRLELEDKVRhYEKQLDDTRVASEQEQAAMKQKYEQGVHTLEKRVSELRSEIADLEGQAAV 685
Cdd:TIGR02169  188 RLDLIIDEKRQQLER----LRREREKAER-YQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISE 262
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   686 LREAHHKASCRHEEEKRQLQMAFDEEKAQLQEELrqeheRELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQ 765
Cdd:TIGR02169  263 LEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKI-----GELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAE 337
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   766 LLSLEEKHALEKEElreelsehhRRELQEGREEMETECNRRVSQIEAQCQADCEKVTEHcEQTLQSLE--VRHRQELRDL 843
Cdd:TIGR02169  338 IEELEREIEEERKR---------RDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL-KDYREKLEklKREINELKRE 407
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   844 LDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRERATAAAMKQEQEILERTYKDrlniLSTERKQLLQDLKDLQNASE 923
Cdd:TIGR02169  408 LDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAAD----LSKYEQELYDLKEEYDRVEK 483

                   ....*
gi 554506543   924 SQHGL 928
Cdd:TIGR02169  484 ELSKL 488
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
442-1023 8.96e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 54.46  E-value: 8.96e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   442 EQMLQQVGKQRVELEQEIQKAKTE-ENYIRDRLALSLKENNRLETELLENAEKlaEYESLTQKLQRSlenvlaeKFGDLD 520
Cdd:pfam12128  199 KSMIVAILEDDGVVPPKSRLNRQQvEHWIRDIQAIAGIMKIRPEFTKLQQEFN--TLESAELRLSHL-------HFGYKS 269
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   521 PSSAEFFLQEERlAQMRNEYEQQCRLLQDQVDELQSELEE---------YQAQGRVLRLPLKNSLSEELDGHSGGIEPDQ 591
Cdd:pfam12128  270 DETLIASRQEER-QETSAELNQLLRTLDDQWKEKRDELNGelsaadaavAKDRSELEALEDQHGAFLDADIETAAADQEQ 348
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   592 GPG-SEECNPLNMSIEAEL-VIEQMKEQHHRDLCHLRLELEDKVRHYEKQLDDTRVASEQEQAAMKQKYEQgvhtLEkrv 669
Cdd:pfam12128  349 LPSwQSELENLEERLKALTgKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQA----LE--- 421
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   670 SELRSEiadLEGQAAVLREAHHKASCRHEEEKRQLQMAFDEEKAQLQEELRQ---EHERE-----------LQARLQQAA 735
Cdd:pfam12128  422 SELREQ---LEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFDeriERAREeqeaanaeverLQSELRQAR 498
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   736 ESFRQEREGLAQAAWTEEKVRGLEQSYQEQL----------LSLEEKHALEKEELREELSEHHRREL-------QEGREE 798
Cdd:pfam12128  499 KRRDQASEALRQASRRLEERQSALDELELQLfpqagtllhfLRKEAPDWEQSIGKVISPELLHRTDLdpevwdgSVGGEL 578
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   799 METECNRRVSQIEAQCQADCEkvtEHCEQTLQSLEvRHRQELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQR 878
Cdd:pfam12128  579 NLYGVKLDLKRIDVPEWAASE---EELRERLDKAE-EALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLD 654
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   879 ERATAAAMKQEQEILERTYKDRLNILSTERKQLLQDLKDLQNASEsqhgllsgQILELKRSQERELRDQGQALCQTGVSE 958
Cdd:pfam12128  655 LRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQ--------AWLEEQKEQKREARTEKQAYWQVVEGA 726
                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 554506543   959 QlaSQQLERLRVEHEQERREMTGKLAALESAHRASL-------ERADQEKAEMSTEICRLQNTVKDMQQAAS 1023
Cdd:pfam12128  727 L--DAQLALLKAAIAARRSGAKAELKALETWYKRDLaslgvdpDVIAKLKREIRTLERKIERIAVRRQEVLR 796
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
627-1322 9.07e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 54.29  E-value: 9.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   627 LELEDKVRHYEKQLDDTRVASEQEQaamKQKYEQGVHTLEKRVSELRSEIADLEGQAAVLREAHHKAscrhEEEKRQLQM 706
Cdd:TIGR02168  216 KELKAELRELELALLVLRLEELREE---LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL----EEEIEELQK 288
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   707 AFDEeKAQLQEELRQEhERELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALEKEELREELSE 786
Cdd:TIGR02168  289 ELYA-LANEISRLEQQ-KQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE 366
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   787 HHRRE--LQEGREEMETEcNRRVSQIEAQcQADCEKVTEHCEQTLQSLEVRHRQELRDLLDQhleERSQWEFEKDELTQE 864
Cdd:TIGR02168  367 LEELEsrLEELEEQLETL-RSKVAQLELQ-IASLNNEIERLEARLERLEDRRERLQQEIEEL---LKKLEEAELKELQAE 441
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   865 CTDAQEQLKEALQRERATAAAMKQEQEILE------RTYKDRLNILSTERKQLLQDLKDLQNASE---------SQHGLL 929
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEeaeqalDAAERELAQLQARLDSLERLQENLEGFSEgvkallknqSGLSGI 521
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   930 SGQILELKRSQER-------ELRDQGQALCQTGVSEQLASQQLERlrvEHEQERREM----TGKLAALESAHRASLER-- 996
Cdd:TIGR02168  522 LGVLSELISVDEGyeaaieaALGGRLQAVVVENLNAAKKAIAFLK---QNELGRVTFlpldSIKGTEIQGNDREILKNie 598
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   997 ------ADQEKAEMSTEIC---RLQNT--VKDMQQAASLLMLQGGCQA---TAGEEAEGDGAMSllqqGEQLLEENGdvL 1062
Cdd:TIGR02168  599 gflgvaKDLVKFDPKLRKAlsyLLGGVlvVDDLDNALELAKKLRPGYRivtLDGDLVRPGGVIT----GGSAKTNSS--I 672
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1063 ISLQRAHEHAVKENAKMATEISRLQQRLKKLEpgsvisSCLEEGTSEISGSSREQVEPIMKQGPATKHFLSDLGDHE--A 1140
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEKALAELR------KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEqlE 746
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1141 RDLASTGTSSVQRQECKTEASEASLDCFSELENSEDTRTESW----DLKSQISQLREQLTVLRADCDRASERKQDLLFDI 1216
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEaqieQLKEELKALREALDELRAELTLLNEEAANLRERL 826
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1217 SVLKKKLKMLERLPEASsrykvlyEDAARENSCLQEELRLVETRYEESLDsnkELTAEVYRLQDEMKKMEEVMEtflSLE 1296
Cdd:TIGR02168  827 ESLERRIAATERRLEDL-------EEQIEELSEDIESLAAEIEELEELIE---ELESELEALLNERASLEEALA---LLR 893
                          730       740
                   ....*....|....*....|....*.
gi 554506543  1297 KSYDEVKVENEELRALVLRLQGKMEK 1322
Cdd:TIGR02168  894 SELEELSEELRELESKRSELRRELEE 919
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1467-1795 1.13e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 1.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1467 RQKDAPSQGQKEEELKAMMQDLQITCGEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQ 1546
Cdd:TIGR02169  665 GILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEE 744
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1547 KIETIEQEKASIQTMVEKLKKQVSDLKIKNQQLdsenielsqknsqnKEELKTLNQRLAEmlcqreepgactsEKWEQEN 1626
Cdd:TIGR02169  745 DLSSLEQEIENVKSELKELEARIEELEEDLHKL--------------EEALNDLEARLSH-------------SRIPEIQ 797
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1627 ASLkEELDHYKVQTSTLVSSLEAELSEVKLQTHVMEQENLLLKDELERLK--QLHRCPDLSDFQQKMSSILSYNEKLLKE 1704
Cdd:TIGR02169  798 AEL-SKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKeqIKSIEKEIENLNGKKEELEEELEELEAA 876
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1705 KEVLSEELKSCADKLAEsslLEHRIATMKQEQTAWEEQSESLKSQLAVSQAKVQNLEDVLQNVNLQMAEIES------DL 1778
Cdd:TIGR02169  877 LRDLESRLGDLKKERDE---LEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEipeeelSL 953
                          330
                   ....*....|....*..
gi 554506543  1779 QVTRQEKEALKQEVMSL 1795
Cdd:TIGR02169  954 EDVQAELQRVEEEIRAL 970
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
1207-1942 1.53e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.52  E-value: 1.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1207 ERKQDLLFDisvLKKKLKMLERLPEASSRYKVLYEDaarenscLQE-ELRLVETRYEESLDSNKELTAEVYRLQDEMKKM 1285
Cdd:TIGR02168  189 DRLEDILNE---LERQLKSLERQAEKAERYKELKAE-------LRElELALLVLRLEELREELEELQEELKEAEEELEEL 258
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1286 EEVMETflsLEKSYDEVKVENEELRALVLRLQGKmekvlgraalQGDSYALWEAPSENLEVAsDEKMLELRQTPKEctpk 1365
Cdd:TIGR02168  259 TAELQE---LEEKLEELRLEVSELEEEIEELQKE----------LYALANEISRLEQQKQIL-RERLANLERQLEE---- 320
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1366 vvsmhhiIEECTQETQCCEQGSTKLLARIKAhEIAWFHRAIKTHPEKPSAQNRVIPEGSAALLGLQDKHLQQEATIAELE 1445
Cdd:TIGR02168  321 -------LEAQLEELESKLDELAEELAELEE-KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1446 LEKQKLQELTRNLRERVTALVRQKDAPSQGQKEEELK---AMMQDLQITCGEMQRKVELLRYESEKLQEENSILRNEITT 1522
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKleeAELKELQAELEELEEELEELQEELERLEEALEELREELEE 472
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1523 LNEEDSISNLKLEELNGSQEELwqkiETIEQEKASIQTMVEKLKKQVSDLKIKNQQLdSENIELSQKNSQNKEelKTLNQ 1602
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSL----ERLQENLEGFSEGVKALLKNQSGLSGILGVL-SELISVDEGYEAAIE--AALGG 545
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1603 RLAEMLCQREEPgactsekWEQENASLKEElDHYKVQTSTLVSSLEAELSEVKLQTHVMEQENLLLKDELE--------- 1673
Cdd:TIGR02168  546 RLQAVVVENLNA-------AKKAIAFLKQN-ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVkfdpklrka 617
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1674 ---RLKQLHRCPDLSDFQQkMSSILSYNEKL--LKEKEVLSEELKSCADKLAESSLLEHR--IATMKQEQTAWEEQSESL 1746
Cdd:TIGR02168  618 lsyLLGGVLVVDDLDNALE-LAKKLRPGYRIvtLDGDLVRPGGVITGGSAKTNSSILERRreIEELEEKIEELEEKIAEL 696
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1747 KSQLAVSQAKVQNLEDVLQNVNLQMAEIESDLQVTRQEKEALKQEVMSLHRQLQNAidkdwvsetapHLSGLRGQQRRLS 1826
Cdd:TIGR02168  697 EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL-----------SKELTELEAEIEE 765
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1827 WDKLDHLMNEEPQLLCQESKRLQTVVQNTQADLTHSREKVRQLESNLLPTKhQKQLNQPCTVKSTEQEKLTLKRECEQSQ 1906
Cdd:TIGR02168  766 LEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLN-EEAANLRERLESLERRIAATERRLEDLE 844
                          730       740       750       760
                   ....*....|....*....|....*....|....*....|
gi 554506543  1907 KEQSPTSRKV----GQMGSLERGLETIHLENEGLKKKQMQ 1942
Cdd:TIGR02168  845 EQIEELSEDIeslaAEIEELEELIEELESELEALLNERAS 884
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
387-771 1.71e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.52  E-value: 1.71e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   387 RSDLDKAEKLKSLMASEVDDHHAAIERrneynLRKLDEEYKERIAALKNELrQEREQMLQQVGKQRVELEQEIQKAKTEE 466
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAE-----LRKELEELEEELEQLRKEL-EELSRQISALRKDLARLEAEVEQLEERI 749
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   467 NYIRDRLALSLKENNRLETELLENAEKLAEYESLTQKLQRSLENVlaekfgdldpsSAEFFLQEERLAQMRNEYEQQCRL 546
Cdd:TIGR02168  750 AQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL-----------KEELKALREALDELRAELTLLNEE 818
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   547 LQDQVDELQSELEEYQAQGRVLRlplknslseeldghsggiepdqgpgseecnplnmsiEAELVIEQMKEQhhrdLCHLR 626
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLE------------------------------------DLEEQIEELSED----IESLA 858
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   627 LELEDKVRHYEKQLDDTRVASEQeqaamKQKYEQGVHTLEKRVSELRSEIADLEGQAAVLREAHHKASCRHEEEKRQLQm 706
Cdd:TIGR02168  859 AEIEELEELIEELESELEALLNE-----RASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE- 932
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 554506543   707 AFDEEKAQLQEELRQEHERELqarlqQAAESFRQEREGLAQAAwtEEKVRGLEQSYQE----QLLSLEE 771
Cdd:TIGR02168  933 GLEVRIDNLQERLSEEYSLTL-----EEAEALENKIEDDEEEA--RRRLKRLENKIKElgpvNLAAIEE 994
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
682-1088 2.49e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 53.03  E-value: 2.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  682 QAAVLREAHHKA-SCRHEEEKRQLQMAfdEEKAQLQEElrqehERELQARLQQAAESFRQEREGLAQAawteEKVrgleQ 760
Cdd:COG3096   286 RALELRRELFGArRQLAEEQYRLVEMA--RELEELSAR-----ESDLEQDYQAASDHLNLVQTALRQQ----EKI----E 350
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  761 SYQEQLLSLEEKHALEKEELREELSEHHRRELQEGREEMETECNRrvSQIEAQCQADCEKVTE--HCEQTLQSLE-VRHR 837
Cdd:COG3096   351 RYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLK--SQLADYQQALDVQQTRaiQYQQAVQALEkARAL 428
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  838 QELRDLLDQHLEER-SQWEFEKDELTQECTDAQEQLKEALQRERATAAAMKQEQEILERTykDRLNILSTERkQLLQDLK 916
Cdd:COG3096   429 CGLPDLTPENAEDYlAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEV--ERSQAWQTAR-ELLRRYR 505
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  917 DLQNASESQHGLlSGQILELKR--SQERELRDQGQALCQTGVSEQLASQQLERLRVEHEQERREMTGKLAAlESAHRASL 994
Cdd:COG3096   506 SQQALAQRLQQL-RAQLAELEQrlRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAE-AVEQRSEL 583
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  995 ERADQEKAEMSTEICRLQNTVKDMQQAASLLMLQGGCQATAGEEaegdgamsLLQQGEQLLEEngdvLISLQRAHEHAVK 1074
Cdd:COG3096   584 RQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEALADSQE--------VTAAMQQLLER----EREATVERDELAA 651
                         410
                  ....*....|....
gi 554506543 1075 ENAKMATEISRLQQ 1088
Cdd:COG3096   652 RKQALESQIERLSQ 665
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1186-1603 6.46e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 6.46e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1186 SQISQLREQLTVLRADCDRASERKQDLLFDISVLKKKLKMLERLPEASSRYKVlyedaarenscLQEELRlvETRYEESL 1265
Cdd:TIGR02169  163 AGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQA-----------LLKEKR--EYEGYELL 229
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1266 DSNKELTAEVYRLQDEMKkmeevmetflSLEKSYDEVKVENEELRALVLRLQGKMEKVlgraalqgdsyalweapSENLE 1345
Cdd:TIGR02169  230 KEKEALERQKEAIERQLA----------SLEEELEKLTEEISELEKRLEEIEQLLEEL-----------------NKKIK 282
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1346 VASDEKMLELRQTPKECTPKVVSMHHIIEECTQETQCCEQGSTKLLARIkaHEIAWFHRAIKTHpekpsaqnrvipegsa 1425
Cdd:TIGR02169  283 DLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEI--DKLLAEIEELERE---------------- 344
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1426 allgLQDKHLQQEATIAELELEKQKLQELTRNLRERVTALVRQKDAPSQGQKEEElkammqDLQITCGEMQRKVELLRYE 1505
Cdd:TIGR02169  345 ----IEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLE------KLKREINELKRELDRLQEE 414
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1506 SEKLQEENSILRNEITTLNEedsisnlKLEELNGSQEELWQKIETIEQEKASIQTMVEKLKKQVSDLKIKNQQLDSENIE 1585
Cdd:TIGR02169  415 LQRLSEELADLNAAIAGIEA-------KINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSK 487
                          410
                   ....*....|....*...
gi 554506543  1586 LSQKNSQNKEELKTLNQR 1603
Cdd:TIGR02169  488 LQRELAEAEAQARASEER 505
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1169-1711 8.90e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 8.90e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1169 SELENSEDTRTESWDLKSQISQLREQLTVLRADCDRASERKQDLLFDISVLKKKLKMLErlpEASSRYKVLYEDAarens 1248
Cdd:PRK03918  221 EELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE---EKVKELKELKEKA----- 292
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1249 clqEELRLVETRYEESLDSNKELTAEVYRLQDEMKKMEEVMETFLSLEKSYDEVKVENEELRALVLRLQGKMEKVLGRAA 1328
Cdd:PRK03918  293 ---EEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKA 369
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1329 LQGDSYALwEAPSENLEVASDEKMLELRQTPKEctpkvvSMHHIIEECTQETQCCEQGSTKLLARIKaheiawfhrAIKT 1408
Cdd:PRK03918  370 KKEELERL-KKRLTGLTPEKLEKELEELEKAKE------EIEEEISKITARIGELKKEIKELKKAIE---------ELKK 433
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1409 HPEKPSAQNRVIPEGSAALLgLQDKHLQQEATIAELELEKQKLQELTRNLRERVTALVRQKDAPSQGQKEEELKAMMQDL 1488
Cdd:PRK03918  434 AKGKCPVCGRELTEEHRKEL-LEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKL 512
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1489 Q-ITCGEMQRKVEllryESEKLQEENSILRNEITTLNEEDSisnlKLEELNGSQEELWQKIETIEQEKASIQTMVEKLK- 1566
Cdd:PRK03918  513 KkYNLEELEKKAE----EYEKLKEKLIKLKGEIKSLKKELE----KLEELKKKLAELEKKLDELEEELAELLKELEELGf 584
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1567 KQVSDLKIKNQQLDS---ENIELSQKNSQNKEELKTLnQRLAEMLCQREEPGACTSEKWEQENASLKEELDHYKVQT--- 1640
Cdd:PRK03918  585 ESVEELEERLKELEPfynEYLELKDAEKELEREEKEL-KKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyee 663
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 554506543 1641 --------STLVSSLEAELSEVKLQTHVMEQENLLLKDELERLKQLHRcpDLSDFQQKMSSILSYNEKLLKEKEVLSEE 1711
Cdd:PRK03918  664 lreeylelSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKK--ELEKLEKALERVEELREKVKKYKALLKER 740
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
529-977 9.92e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.54  E-value: 9.92e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  529 QEERLAQMRNEYEQqCRLLQDQVDELQSELEEYQAQGRVLRLPLKnSLSEELDGHSGGIEPDQgpgseecnplnmsIEAE 608
Cdd:COG4717    76 LEEELKEAEEKEEE-YAELQEELEELEEELEELEAELEELREELE-KLEKLLQLLPLYQELEA-------------LEAE 140
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  609 LVIEQMKEQHHRDLCHLRLELEDKVRHYEKQLDDTRVASEQEQAAMKQKYEQGVHTLEKRVSELRSEIADLEGQAAVLRE 688
Cdd:COG4717   141 LAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQE 220
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  689 AHHKASCRHEEEKRQLQMAFDEEK-AQLQEELRQEHERELQARLQQAAESFRQEREGLAQA--------AWTEEKVRGLE 759
Cdd:COG4717   221 ELEELEEELEQLENELEAAALEERlKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLvlgllallFLLLAREKASL 300
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  760 QSYQEQLLSLEEKHALEKEELREELSEHH------RRELQEGREEMETECNRRVSQIEAQCQADCEKVTEHCEQTLQSLE 833
Cdd:COG4717   301 GKEAEELQALPALEELEEEELEELLAALGlppdlsPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAG 380
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  834 VRHRQELRDLLDQHLEERsqwefekdELTQECTDAQEQLKEALQRERATAAAMKQEQ-EILERTYKDRLNILSTERKQLL 912
Cdd:COG4717   381 VEDEEELRAALEQAEEYQ--------ELKEELEELEEQLEELLGELEELLEALDEEElEEELEELEEELEELEEELEELR 452
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 554506543  913 QDLKDLQNASESqhgLLSGQILELKRSQERELRDQGQALCQTGVSEQLASQQLERLRVEHEQERR 977
Cdd:COG4717   453 EELAELEAELEQ---LEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
368-581 1.06e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 50.70  E-value: 1.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  368 EIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALkNELRQEREQMLQQ 447
Cdd:PRK05771   44 RLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEI-SELENEIKELEQE 122
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  448 vgKQRVE----LEQEIQKAKTEENYIrdRLALSLKENNRLETELLENAEKLAEYESLTQKL------QRSLENVLAEKFG 517
Cdd:PRK05771  123 --IERLEpwgnFDLDLSLLLGFKYVS--VFVGTVPEDKLEELKLESDVENVEYISTDKGYVyvvvvvLKELSDEVEEELK 198
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 554506543  518 DLDPSSAEFFlQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPLKNSLSEELD 581
Cdd:PRK05771  199 KLGFERLELE-EEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEIELE 261
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
381-850 1.58e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.15  E-value: 1.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  381 REKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYnlrkldEEYKERIAALKNELRQEREQMLQQvgKQRVELEQEIQ 460
Cdd:COG4717    64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEEL------EEELEELEAELEELREELEKLEKL--LQLLPLYQELE 135
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  461 KAKTEENYIRDRLalslkenNRLETELLENAEKLAEYESLTQKLQRsLENVLAEKFGDLDPSSAEfflQEERLAQMRNEY 540
Cdd:COG4717   136 ALEAELAELPERL-------EELEERLEELRELEEELEELEAELAE-LQEELEELLEQLSLATEE---ELQDLAEELEEL 204
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  541 EQQCRLLQDQVDELQSELEEYQAQGRVLRLPL-KNSLSEELDGHS------GGIEPDQGPGSEECNPLNMSIEAELVIEQ 613
Cdd:COG4717   205 QQRLAELEEELEEAQEELEELEEELEQLENELeAAALEERLKEARlllliaAALLALLGLGGSLLSLILTIAGVLFLVLG 284
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  614 MKEQHHRDLCHLRLELEDKVRHYEKQLDDTRVAsEQEQAAMKQKYEQGVHTLEKRVSELRSEIADLEGQAAVLREAHHKA 693
Cdd:COG4717   285 LLALLFLLLAREKASLGKEAEELQALPALEELE-EEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL 363
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  694 SCRHEEEKRQ--LQMAFDEEKAQLQEELRQ-EHERELQARLQQAAESFRQEREGLAQ--AAWTEEKVRGLEQSYQEQLLS 768
Cdd:COG4717   364 QLEELEQEIAalLAEAGVEDEEELRAALEQaEEYQELKEELEELEEQLEELLGELEEllEALDEEELEEELEELEEELEE 443
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  769 LEEKHALEKEELREELSEHHRRELQEGREEMETECNRRVSQIEAQCQADCEKVTehCEQTLQSLEVRHRQELRDLLDQHL 848
Cdd:COG4717   444 LEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKL--ALELLEEAREEYREERLPPVLERA 521

                  ..
gi 554506543  849 EE 850
Cdd:COG4717   522 SE 523
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1540-1827 1.95e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1540 SQEELWQKIETIEQEKASIQTMVEKLKKQVSDLKIKNQQLDSENIELSQKNSQNKEELKTLNQRLAEMlcqreepgacts 1619
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAEL------------ 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1620 ekwEQENASLKEELDhykvqtstlvsSLEAELSEVKLQTHVMEQENlllkdeleRLKQLHRCPDLSDFQQKMSSILSYNE 1699
Cdd:COG4942    89 ---EKEIAELRAELE-----------AQKEELAELLRALYRLGRQP--------PLALLLSPEDFLDAVRRLQYLKYLAP 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1700 KLLKEKEVLSEELKscadklaessllehRIATMKQEQtawEEQSESLKSQLAVSQAKVQNLEDVLQNVNLQMAEIESDLQ 1779
Cdd:COG4942   147 ARREQAEELRADLA--------------ELAALRAEL---EAERAELEALLAELEEERAALEALKAERQKLLARLEKELA 209
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 554506543 1780 VTRQEKEALKQEVMSLHRQLQNAIDKDWVSETAPHLSGLRGQQRRLSW 1827
Cdd:COG4942   210 ELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKLPW 257
PTZ00121 PTZ00121
MAEBL; Provisional
366-935 2.05e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 2.05e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  366 KAEIRHLLERVDQVVREKEKLRSDLDKAEKLKslmasEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNElrQEREQML 445
Cdd:PTZ00121 1259 EARMAHFARRQAAIKAEEARKADELKKAEEKK-----KADEAKKAEEKKKADEAKKKAEEAKKADEAKKKA--EEAKKKA 1331
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  446 QQVGKQRVELEQEIQKAKTEENYIRDRLALSLKENNRLETELLENAEKLAEYESLTQKLQRSLEnvlAEKFGDLDPSSAE 525
Cdd:PTZ00121 1332 DAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADE---AKKKAEEDKKKAD 1408
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  526 FFLQEERLAQMRNEYEQQCRLLQdQVDELQSELEEYQAQGRVLRLPLKNSLSEELDGHSggiepdqgpgsEECNplnmsi 605
Cdd:PTZ00121 1409 ELKKAAAAKKKADEAKKKAEEKK-KADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKA-----------EEAK------ 1470
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  606 EAELVIEQMKEQHHRDlchlrlELEDKVRHYEKQLDDTRVASEQeqaamKQKYEQGVHTLEKRVSElRSEIADLEGQAAV 685
Cdd:PTZ00121 1471 KADEAKKKAEEAKKAD------EAKKKAEEAKKKADEAKKAAEA-----KKKADEAKKAEEAKKAD-EAKKAEEAKKADE 1538
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  686 LREAHHKAscRHEEEKRQLQMAFDEEKAQLQEELRQEHERELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQ 765
Cdd:PTZ00121 1539 AKKAEEKK--KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAE 1616
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  766 LLSLEEKHALEKEELREELSEHHRRELQEGREEMETECNRRVSQIEAQCQADCEKVTEHCEQTLQSLEVRHRQELRDLLD 845
Cdd:PTZ00121 1617 EAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKK 1696
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  846 QHLEERSQWEFEKDElTQECTDAQEQLKEALQRERATAAAMKQEQEilERTYKDRLNILSTERKQLLQDLKDLQNASESQ 925
Cdd:PTZ00121 1697 EAEEAKKAEELKKKE-AEEKKKAEELKKAEEENKIKAEEAKKEAEE--DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
                         570
                  ....*....|
gi 554506543  926 HGLLSGQILE 935
Cdd:PTZ00121 1774 RKEKEAVIEE 1783
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1411-1664 2.09e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.68  E-value: 2.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1411 EKPSAQNRVIPEGSAALLGLQDKHLQQEATIAELELEKQKLQELTRNLRERVTALVRQKDapsqGQKEEELKAMMQDLQI 1490
Cdd:TIGR02169  730 QEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLS----HSRIPEIQAELSKLEE 805
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1491 TCGEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQTMVEKLKKQVS 1570
Cdd:TIGR02169  806 EVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG 885
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1571 DLKIKNQQLDSENIELSQKNSQNKEELKTLNQRLAEMLCQREEpgactsekweqenasLKEELDHYKVQTSTLVSSLEAE 1650
Cdd:TIGR02169  886 DLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA---------------LEEELSEIEDPKGEDEEIPEEE 950
                          250
                   ....*....|....
gi 554506543  1651 LSEVKLQTHVMEQE 1664
Cdd:TIGR02169  951 LSLEDVQAELQRVE 964
PTZ00121 PTZ00121
MAEBL; Provisional
638-1322 2.21e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 2.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  638 KQLDDTRVASEQEQAAMKQKYEQGVHTLEKRvselRSEIADLEGQAAVLREAHHKASCRHEEEKRQLQMAFDEEKAQLQE 717
Cdd:PTZ00121 1104 KKTETGKAEEARKAEEAKKKAEDARKAEEAR----KAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAE 1179
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  718 ELRQEHERELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALEKEELREELSEHHRRELQEGRE 797
Cdd:PTZ00121 1180 AARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEE 1259
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  798 EMETECNRRVSQIEAQCQADCEKVTEhCEQTLQSLEVRHRQELR--DLLDQHLEERSQWEFEKDELTQECTDAQEQLKEA 875
Cdd:PTZ00121 1260 ARMAHFARRQAAIKAEEARKADELKK-AEEKKKADEAKKAEEKKkaDEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKA 1338
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  876 LQRERATAAAMKQEQEILERTYKdrlnilsTERKQLLQDLKDLQNASESQHglLSGQILELKRSQERelrdQGQALCQTG 955
Cdd:PTZ00121 1339 EEAKKAAEAAKAEAEAAADEAEA-------AEEKAEAAEKKKEEAKKKADA--AKKKAEEKKKADEA----KKKAEEDKK 1405
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  956 VSEQLASQQLERLRVEHEQERREMTGKlaALESAHRASLERADQEKAEMSTEICRLQNTVKDMQQAASLLMLqggcQATA 1035
Cdd:PTZ00121 1406 KADELKKAAAAKKKADEAKKKAEEKKK--ADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEA----KKKA 1479
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1036 GEEAEGDGAMSLLQQGEQLLEENGDVLISLQRAHEHAVKENAKMATEISRLQQRLKKLEpgsvisscLEEGTSEISGSSR 1115
Cdd:PTZ00121 1480 EEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADE--------AKKAEEKKKADEL 1551
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1116 EQVEPIMKQGPATKHflsdlgdHEARDLASTGTSSVQRQECKTEASEASLDCFSELENSEDTrteswdLKSQISQLREQL 1195
Cdd:PTZ00121 1552 KKAEELKKAEEKKKA-------EEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKK------MKAEEAKKAEEA 1618
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1196 TVLRADCDRASERKQDLLFDISVLKKKLKMLERLPEASSRYKVLYEDAARENsclQEELRLVETRYEESLDSNKELTAeV 1275
Cdd:PTZ00121 1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA---EEDKKKAEEAKKAEEDEKKAAEA-L 1694
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*..
gi 554506543 1276 YRLQDEMKKMEEVMETFLSLEKSYDEVKVENEELRALVLRLQGKMEK 1322
Cdd:PTZ00121 1695 KKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE 1741
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1431-1798 3.08e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.00  E-value: 3.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1431 QDKHLQQEATIAELELEKQKLQELTRNLRERVTALVRQKDAPSQGQKEEELKAMMQDLQITCGEMQRKVEL---LRYESE 1507
Cdd:COG4717    87 EEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEElreLEEELE 166
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1508 KLQEENSILRNEITTLNEEDSISNLK-LEELNGSQEELWQKIETIEQEKASIQTMVEKLKKQVSDLkiknqQLDSENIEL 1586
Cdd:COG4717   167 ELEAELAELQEELEELLEQLSLATEEeLQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL-----ENELEAAAL 241
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1587 SQKNSQNKEELKTLNQRLA----------------------------EMLCQREEPGACTSEKWEQENASLKEELDHYKV 1638
Cdd:COG4717   242 EERLKEARLLLLIAAALLAllglggsllsliltiagvlflvlgllalLFLLLAREKASLGKEAEELQALPALEELEEEEL 321
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1639 QTSTLVSSLEAELSEVKLQTHVMEQENllLKDELERLKQLHRCPDLSDFQQKMSSILSYNE-----------KLLKEKEV 1707
Cdd:COG4717   322 EELLAALGLPPDLSPEELLELLDRIEE--LQELLREAEELEEELQLEELEQEIAALLAEAGvedeeelraalEQAEEYQE 399
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1708 LSEELKSCADKLAESSLLEHRIATMKQEqTAWEEQSESLKSQLAVSQAKVQNLEDVLQNVNLQMAEIESD--LQVTRQEK 1785
Cdd:COG4717   400 LKEELEELEEQLEELLGELEELLEALDE-EELEEELEELEEELEELEEELEELREELAELEAELEQLEEDgeLAELLQEL 478
                         410
                  ....*....|...
gi 554506543 1786 EALKQEVMSLHRQ 1798
Cdd:COG4717   479 EELKAELRELAEE 491
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
307-505 4.32e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.47  E-value: 4.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  307 VERILDTWQEEGIE-NSQEILKALDFsLDGNINLTELTL-ALENELLVTKNgihQAALASFKAEIRHLLERVDQVVREKE 384
Cdd:COG3206   154 ANALAEAYLEQNLElRREEARKALEF-LEEQLPELRKELeEAEAALEEFRQ---KNGLVDLSEEAKLLLQQLSELESQLA 229
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  385 KLRSDLDKAE----------KLKSLMASEVDDHHAAIERRNEYN-----LRKLDEEYKE---RIAALKNELRQEREQMLQ 446
Cdd:COG3206   230 EARAELAEAEarlaalraqlGSGPDALPELLQSPVIQQLRAQLAeleaeLAELSARYTPnhpDVIALRAQIAALRAQLQQ 309
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 554506543  447 QVGKQRVELEQEIQKAKTEENYIRDRLAlslkennRLETELLENAEKLAEYESLTQKLQ 505
Cdd:COG3206   310 EAQRILASLEAELEALQAREASLQAQLA-------QLEARLAELPELEAELRRLEREVE 361
PTZ00121 PTZ00121
MAEBL; Provisional
401-1003 6.10e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.60  E-value: 6.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  401 ASEVDDHHAAIERRNEYNLRKLdEEYKERIAALKNELRQEREQMLQQVGKQRVELEQEIQKAKTEEN------YIRDRLA 474
Cdd:PTZ00121 1175 AKKAEAARKAEEVRKAEELRKA-EDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEeakkaeEERNNEE 1253
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  475 LSLKENNRLETELLENAEKLAEYESLTQKLQRSLENVLAEKFGDLDP-SSAEFFLQEERLAQMRNEYEQQCRLLQDQVDE 553
Cdd:PTZ00121 1254 IRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEkKKADEAKKKAEEAKKADEAKKKAEEAKKKADA 1333
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  554 LQSELEEYQAQGRVLRLPLKNSlSEELDGHSGGIEPDQGPGSEEcnplnmSIEAELVIEQMKEQHHRDlchlrlELEDKV 633
Cdd:PTZ00121 1334 AKKKAEEAKKAAEAAKAEAEAA-ADEAEAAEEKAEAAEKKKEEA------KKKADAAKKKAEEKKKAD------EAKKKA 1400
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  634 RHYEKQLDDTRVASEQEQAA--MKQKYEqgvhtlEKRVSElrseiadlegqaavlrEAHHKAscrhEEEKRQLQMAFDEE 711
Cdd:PTZ00121 1401 EEDKKKADELKKAAAAKKKAdeAKKKAE------EKKKAD----------------EAKKKA----EEAKKADEAKKKAE 1454
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  712 KAQLQEELRQEHERELQA-RLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALEKEELREELSEHHRR 790
Cdd:PTZ00121 1455 EAKKAEEAKKKAEEAKKAdEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK 1534
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  791 ELQEGREEMETECNRRVSQIEAQCQADCEKVTEHC--EQTLQSLEVRHRQELRDLldqhleERSQWEFEKDELTQECTDA 868
Cdd:PTZ00121 1535 KADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAkkAEEDKNMALRKAEEAKKA------EEARIEEVMKLYEEEKKMK 1608
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  869 QEQLKEAlQRERATAAAMKQEQEilERTYKDRLNILSTERKQLLQDLKDLQNASESQHGLLSGQILELKRSQE--RELRD 946
Cdd:PTZ00121 1609 AEEAKKA-EEAKIKAEELKKAEE--EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEeaKKAEE 1685
                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 554506543  947 QGQALCQTGVSEQLASQQLERLRVEHEQERREMTgKLAALESAHRASLERADQEKAE 1003
Cdd:PTZ00121 1686 DEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAE-ELKKAEEENKIKAEEAKKEAEE 1741
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1168-1770 8.75e-05

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 47.77  E-value: 8.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1168 FSELENSEDTRTESWDLKsqisQLREQLTVLRADCDRASERKQDLLFDISV---LKKKLKMLERLpeassRYKVLYEDAA 1244
Cdd:COG5022   861 FSLLKKETIYLQSAQRVE----LAERQLQELKIDVKSISSLKLVNLELESEiieLKKSLSSDLIE-----NLEFKTELIA 931
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1245 RENSCLQEelrlveTRYEESLDSNKELTAEVYRLQDEMKKMEEVMETFLSLEKSYDEVKVENEELRALVLRLQGKM-EKV 1323
Cdd:COG5022   932 RLKKLLNN------IDLEEGPSIEYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELaELS 1005
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1324 LGRAALQGDSYALWEAPSENLEVASDEKML----ELRQTPKEcTPKVVSMHHIIEECTQ----------------ETQCC 1383
Cdd:COG5022  1006 KQYGALQESTKQLKELPVEVAELQSASKIIssesTELSILKP-LQKLKGLLLLENNQLQarykalklrrenslldDKQLY 1084
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1384 EQGSTK-LLARIKAHEIawfhRAIKTHPEKPSAQNRVIPEGSAALLGLQDKHLQQEATIAELELEKQKLQ--ELTRNLRE 1460
Cdd:COG5022  1085 QLESTEnLLKTINVKDL----EVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSvlQLELDGLF 1160
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1461 RVTALVR--QKDAPSQGQKEEELKAMMQDL--QITCGEMQRKVELLryeSEKLQEENSILRNEITTLNEEDSISNLKLEE 1536
Cdd:COG5022  1161 WEANLEAlpSPPPFAALSEKRLYQSALYDEksKLSSSEVNDLKNEL---IALFSKIFSGWPRGDKLKKLISEGWVPTEYS 1237
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1537 LNGSQEELWQKIETIEQEKaSIQTMVEKLKKQVSDLKIKNQQLDSENIELSQknsqnkeELKTLNQRLAEMLCQREEPGA 1616
Cdd:COG5022  1238 TSLKGFNNLNKKFDTPASM-SNEKLLSLLNSIDNLLSSYKLEEEVLPATINS-------LLQYINVGLFNALRTKASSLR 1309
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1617 CTSEKWEQENASLKEELDHykvqtstlvsslEAELSEVKLQTHVMEQENL---LLKDELERLKQLHR-CPDLSDFQqkMS 1692
Cdd:COG5022  1310 WKSATEVNYNSEELDDWCR------------EFEISDVDEELEELIQAVKvlqLLKDDLNKLDELLDaCYSLNPAE--IQ 1375
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1693 SILSYNEKLLKEKEVLSEELK-----SCADKLAESSLLEHRIATMKQEQTAWEEQSESLKSQLAVSQAKVQNLEDVLQNV 1767
Cdd:COG5022  1376 NLKSRYDPADKENNLPKEILKkiealLIKQELQLSLEGKDETEVHLSEIFSEEKSLISLDRNSIYKEEVLSSLSALLTKE 1455

                  ...
gi 554506543 1768 NLQ 1770
Cdd:COG5022  1456 KIA 1458
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
1443-1825 1.03e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.42  E-value: 1.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1443 ELELEKQKLQEL-TRNLRERVTALVRQKDAPSQGQKEEELKAMMQDLQITC-GEMQRKVELLRYESEKLQEENSIL---- 1516
Cdd:pfam15921  392 ELSLEKEQNKRLwDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECqGQMERQMAAIQGKNESLEKVSSLTaqle 471
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1517 --RNEITTLNEEDSISNLKLE-------ELNGSQEELWQKIETIEQEKASIQTMVEKLKKQVSDLKIKNQQLDSENIE-- 1585
Cdd:pfam15921  472 stKEMLRKVVEELTAKKMTLEssertvsDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTEce 551
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1586 -LSQKNSQNKEELKTLNQRLAEMLCQREEPGAcTSEKWEQENASLKEELDHYKVQTStlvsslEAELSEVKLQTHVMEQE 1664
Cdd:pfam15921  552 aLKLQMAEKDKVIEILRQQIENMTQLVGQHGR-TAGAMQVEKAQLEKEINDRRLELQ------EFKILKDKKDAKIRELE 624
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1665 NLLLKDELERLKQLH----RCPDLSDFQQKMSSIL-----SYNE--KLLKEKEVL-------SEELKSCADKL-----AE 1721
Cdd:pfam15921  625 ARVSDLELEKVKLVNagseRLRAVKDIKQERDQLLnevktSRNElnSLSEDYEVLkrnfrnkSEEMETTTNKLkmqlkSA 704
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1722 SSLLEHRIATMKQEQTA----------WEEQSESLKSQLAVSQAKVQNLEDVLQNVNlqmaeiesdlqvtrQEKEALKQE 1791
Cdd:pfam15921  705 QSELEQTRNTLKSMEGSdghamkvamgMQKQITAKRGQIDALQSKIQFLEEAMTNAN--------------KEKHFLKEE 770
                          410       420       430
                   ....*....|....*....|....*....|....
gi 554506543  1792 VMSLHRQLQNAIDKDwvSETAPHLSGLRGQQRRL 1825
Cdd:pfam15921  771 KNKLSQELSTVATEK--NKMAGELEVLRSQERRL 802
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1258-1791 1.32e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.98  E-value: 1.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1258 ETRYEESLDSNKELTAEVYRLQDEMKKMEEVMETFLSLEKSYDEVKVENEELRALVLRLQGKMEKVlgraalqgdsyalw 1337
Cdd:PRK03918  161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKL-------------- 226
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1338 eapsenlevasDEKMLELRQTPKEctpkvvsmhhiIEECTQETQCCEQGSTKLLARIKahEIAWFHRAIKTHPEKPSAQN 1417
Cdd:PRK03918  227 -----------EKEVKELEELKEE-----------IEELEKELESLEGSKRKLEEKIR--ELEERIEELKKEIEELEEKV 282
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1418 RVIPEgsaaLLGLQDKHLQQEATIAELELEKQKLQELTRNLRERVTALVRQ-KDAPSQGQKEEELKAMMQDLQITCGEMQ 1496
Cdd:PRK03918  283 KELKE----LKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERiKELEEKEERLEELKKKLKELEKRLEELE 358
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1497 RKVELLRyESEKLQEENSILRNEITTLNEEDSISnlKLEELNGSQEELWQKIETIEQEKASIQTMVEKLKKQVSDLKIKN 1576
Cdd:PRK03918  359 ERHELYE-EAKAKKEELERLKKRLTGLTPEKLEK--ELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAK 435
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1577 QQLDSENIELSQKNSQN-----KEELKTLNQRLAEMLCQREEpgaCTSEKWEQENASLKEELDHYKVQTSTLVSSLEAEL 1651
Cdd:PRK03918  436 GKCPVCGRELTEEHRKElleeyTAELKRIEKELKEIEEKERK---LRKELRELEKVLKKESELIKLKELAEQLKELEEKL 512
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1652 SEVKLQThvMEQENLLLKDELERLKQLH-RCPDLSDFQQKMSSILSYNEKLLKEKEVLSEELKSCADKLAESSL-----L 1725
Cdd:PRK03918  513 KKYNLEE--LEKKAEEYEKLKEKLIKLKgEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFesveeL 590
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 554506543 1726 EHRIATMKQEQTAWEEQSESlKSQLAVSQAKVQNLEDVLQNVNLQMAEIESDLQVTRQEKEALKQE 1791
Cdd:PRK03918  591 EERLKELEPFYNEYLELKDA-EKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKK 655
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
359-560 1.79e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  359 QAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEyNLRKLdeeyKERIAALKNELR 438
Cdd:COG4942    26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA-ELAEL----EKEIAELRAELE 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  439 QEREQMLQQVGKQ-----------------------RVELEQEIQKAKTEEnyiRDRLALSLKENNRLETELLENAEKLA 495
Cdd:COG4942   101 AQKEELAELLRALyrlgrqpplalllspedfldavrRLQYLKYLAPARREQ---AEELRADLAELAALRAELEAERAELE 177
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 554506543  496 EYESLTQKLQRSLENVLAEKFGDLDPSSAEFFLQEERLAQMRNEYEQqcrlLQDQVDELQSELEE 560
Cdd:COG4942   178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE----LEALIARLEAEAAA 238
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
612-968 1.83e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.87  E-value: 1.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  612 EQMKEQHHRdLCHLRLELEDKVRHYEKQLDDTRVASEQ---EQAAMKQKyeqgvHTLEKRVSELRSEIADLEGQAAVLRE 688
Cdd:COG3096   299 RQLAEEQYR-LVEMARELEELSARESDLEQDYQAASDHlnlVQTALRQQ-----EKIERYQEDLEELTERLEEQEEVVEE 372
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  689 AHHKAScRHEEEKRQLQMAFDEEKAQL---QEELRQEHERELQarLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQ 765
Cdd:COG3096   373 AAEQLA-EAEARLEAAEEEVDSLKSQLadyQQALDVQQTRAIQ--YQQAVQALEKARALCGLPDLTPENAEDYLAAFRAK 449
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  766 -------LLSLEEKHALEKEelreelsehHRRELQEGREEMET---ECNR----------------------RVSQIEAQ 813
Cdd:COG3096   450 eqqateeVLELEQKLSVADA---------ARRQFEKAYELVCKiagEVERsqawqtarellrryrsqqalaqRLQQLRAQ 520
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  814 cQADCEKVTEH---CEQTLQSLEVRHRQEL--RDLLDQHLEErsqWEFEKDELTQECTDAQEQLKEALQRERATAAAMKQ 888
Cdd:COG3096   521 -LAELEQRLRQqqnAERLLEEFCQRIGQQLdaAEELEELLAE---LEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKE 596
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  889 --EQEILERTYKDRLNILSTERKQLLQDLKDLQNASEsqhgllsgQILELKRSQERElRDQGQAlcqtgvSEQLASQQLE 966
Cdd:COG3096   597 laARAPAWLAAQDALERLREQSGEALADSQEVTAAMQ--------QLLEREREATVE-RDELAA------RKQALESQIE 661

                  ..
gi 554506543  967 RL 968
Cdd:COG3096   662 RL 663
PTZ00121 PTZ00121
MAEBL; Provisional
1445-1634 2.72e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.29  E-value: 2.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1445 ELEKQKLQELTRNLRERVTALVRQKDAPSQGQKEEELKAMMQDLQITCGEMQRKVELLRYESEKLQEENSILRNEITTLN 1524
Cdd:PTZ00121 1616 EEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALK 1695
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1525 EEDSISNlKLEELNGSQEELWQKIETIEQEKASIQTMVEKLKKQVSDLKIKNQQLDSENIELSQKNSQNKEELKTLNQrl 1604
Cdd:PTZ00121 1696 KEAEEAK-KAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEE-- 1772
                         170       180       190
                  ....*....|....*....|....*....|
gi 554506543 1605 aemlcQREEPGACTSEKWEQENASLKEELD 1634
Cdd:PTZ00121 1773 -----IRKEKEAVIEEELDEEDEKRRMEVD 1797
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
1441-1793 2.84e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 45.87  E-value: 2.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1441 IAELELEKQKLQELTRNLRERVTalvrqkdapsqgQKEEELKAMMQDLQITCGEMQRKVELLRYESEKLQEENSILRNEI 1520
Cdd:pfam05483  351 VTEFEATTCSLEELLRTEQQRLE------------KNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDE 418
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1521 TTLNEEDSISNLKlEELNGSQEELW-------QKIETIEQEKASIQTMVEKLKKQVSDLKIKNQQLDSENIELSQKNSQN 1593
Cdd:pfam05483  419 KLLDEKKQFEKIA-EELKGKEQELIfllqareKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKL 497
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1594 KEELKTLNQRLAEMLCQREEPgactsekweqenaslKEELDHYKVQTSTLVSSLEAelsevklqthvMEQENLLLKDELE 1673
Cdd:pfam05483  498 LLENKELTQEASDMTLELKKH---------------QEDIINCKKQEERMLKQIEN-----------LEEKEMNLRDELE 551
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1674 RLKQ---LHRCPDLSDFQQKMSSILSYNEKLLKEKEVLSEELKSCADKLAESSLLEHRIATMKQEQTAWEEQSESLKSQL 1750
Cdd:pfam05483  552 SVREefiQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQL 631
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 554506543  1751 AVSQAKVQNLEDVLQNVNLQMAEIESDLQVTRQEKEALKQEVM 1793
Cdd:pfam05483  632 NAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLL 674
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1430-1873 3.41e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 3.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1430 LQDKHLQQEATIAELELEKQKLQELTRNLRERVTALVRQKDApSQGQKEEELKAMMQDLQITCGEMQRKVEllryesekl 1509
Cdd:COG4913   293 LEAELEELRAELARLEAELERLEARLDALREELDELEAQIRG-NGGDRLEQLEREIERLERELEERERRRA--------- 362
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1510 qeensILRNEITTLNEEDSISNLKLEELngsQEELWQKIETIEQEKASIQTMVEKLKKQVSDLKIKNQQLDSENIELSQK 1589
Cdd:COG4913   363 -----RLEALLAALGLPLPASAEEFAAL---RAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1590 NSQNKEELKTLNQRLAEMLCQREE--PGAC-------TSEKWEQ---------------------------ENASLKEEL 1633
Cdd:COG4913   435 KSNIPARLLALRDALAEALGLDEAelPFVGelievrpEEERWRGaiervlggfaltllvppehyaaalrwvNRLHLRGRL 514
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1634 DHYKVQTST----LVSSLEAELSEvKLQTHVMEQENLLlKDELERLKQLHRCPDLSDFQQKMSSI----LSYNEKLLKEK 1705
Cdd:COG4913   515 VYERVRTGLpdpeRPRLDPDSLAG-KLDFKPHPFRAWL-EAELGRRFDYVCVDSPEELRRHPRAItragQVKGNGTRHEK 592
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1706 --------------------EVLSEELKSCADKLAEsslLEHRIATMKQEQTAWEEQSESLKSQLAVS---------QAK 1756
Cdd:COG4913   593 ddrrrirsryvlgfdnraklAALEAELAELEEELAE---AEERLEALEAELDALQERREALQRLAEYSwdeidvasaERE 669
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1757 VQNLEDVLQNVNL----------QMAEIESDLQVTRQEKEALKQEVMSLHRQLQNAidKDWVSETAPHLSGLRGQQRRLS 1826
Cdd:COG4913   670 IAELEAELERLDAssddlaaleeQLEELEAELEELEEELDELKGEIGRLEKELEQA--EEELDELQDRLEAAEDLARLEL 747
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*..
gi 554506543 1827 WDKLDHLMNEEPQllcqeSKRLQTVVQNTQADLTHSREKVRQLESNL 1873
Cdd:COG4913   748 RALLEERFAAALG-----DAVERELRENLEERIDALRARLNRAEEEL 789
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1485-1812 4.42e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.89  E-value: 4.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1485 MQDLQITCGEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQTMVEK 1564
Cdd:COG4372    40 LDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEE 119
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1565 LKKQVSDLKIKNQQLDSENIELSQKNSQNKEELKTLNQRLAEMlcqREEPGACTSEKWEQENASLKEELDHYKVQTSTLV 1644
Cdd:COG4372   120 LQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESL---QEELAALEQELQALSEAEAEQALDELLKEANRNA 196
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1645 SSLEAELSEVKLQthvmEQENLLLKDELERLKQLHRCPDLSDFQQKMSSILSYNEKLLKEKEVLSEELKSCADKLAESSL 1724
Cdd:COG4372   197 EKEEELAEAEKLI----ESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKD 272
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1725 LEHRIATMKQEQTAWEEQSESLKSQLAVSQAKVQNLEDVLQNVNLQMAEIESDLQVTRQEKEALKQEVMSLHRQLQNAID 1804
Cdd:COG4372   273 TEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLD 352

                  ....*...
gi 554506543 1805 KDWVSETA 1812
Cdd:COG4372   353 NDVLELLS 360
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
837-1025 4.85e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 4.85e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  837 RQELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRERATAAAMKQEQEILERTyKDRLNILSTERKQLLQDLK 916
Cdd:COG4942    29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAEL-EKEIAELRAELEAQKEELA 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  917 DL-------------------QNASESQHGL-LSGQILELKRSQERELRDQGQALCQTGVSEQLASQQLERLRVEHEQER 976
Cdd:COG4942   108 ELlralyrlgrqpplalllspEDFLDAVRRLqYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEER 187
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 554506543  977 REmtgkLAALESAHRASLERADQEKAEMSTEICRLQNTVKDMQQAASLL 1025
Cdd:COG4942   188 AA----LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
368-929 4.95e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.42  E-value: 4.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  368 EIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRneynlrkldEEYKERIAALKNELRQEREQmLQQ 447
Cdd:PRK02224  200 EEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEH---------EERREELETLEAEIEDLRET-IAE 269
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  448 VGKQRVELEQEIQKAKTEENYIRDRLALSLKENNRLETELLENAEKLAEYESLTQKLQRSLENVlaekfgdlDPSSAEFF 527
Cdd:PRK02224  270 TEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEEC--------RVAAQAHN 341
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  528 LQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPLKnSLSEELDGHSGGIE--PDQGPGSEEcnplnmsi 605
Cdd:PRK02224  342 EEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIE-ELEEEIEELRERFGdaPVDLGNAED-------- 412
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  606 EAELVIEQMKEQHHR--DLCHLRLELEDKVRHYEKQLDDTRvASEQEQAAMKQKYEQGVHTLEKRVSELRSEIADLEGQA 683
Cdd:PRK02224  413 FLEELREERDELREReaELEATLRTARERVEEAEALLEAGK-CPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEV 491
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  684 AVLREAHHKASCRHEEEKRQLQMafdEEKAQLQEELRQEHERELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQ 763
Cdd:PRK02224  492 EEVEERLERAEDLVEAEDRIERL---EERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAE 568
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  764 EQLLSLEEKHALEKEELREELSEHHRRELQEGREEMETECNRRVSQIEAQCQADCEKvtehcEQTLQSLEVRHRQELRDL 843
Cdd:PRK02224  569 EAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDER-----RERLAEKRERKRELEAEF 643
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  844 LDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRERATAAAMKQEQEILErTYKDRLNILStERKQLLQDLKDLQNASE 923
Cdd:PRK02224  644 DEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELE-ELRERREALE-NRVEALEALYDEAEELE 721

                  ....*.
gi 554506543  924 SQHGLL 929
Cdd:PRK02224  722 SMYGDL 727
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
438-877 6.57e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.94  E-value: 6.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  438 RQEREQMLQQVGKQRVELeQEIQKAKTEENYIRDRLALSLKENNRLETELLenaeklAEYESLTQKLQRSLENV-LAEKF 516
Cdd:COG3096   277 ANERRELSERALELRREL-FGARRQLAEEQYRLVEMARELEELSARESDLE------QDYQAASDHLNLVQTALrQQEKI 349
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  517 G--DLDPSSAEFFLQE-----ERLAQMRNEYEQQCRLLQDQVDELQSELEEYQaQGrvlrlplknslseeLDG-HSGGIE 588
Cdd:COG3096   350 EryQEDLEELTERLEEqeevvEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQ-QA--------------LDVqQTRAIQ 414
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  589 PDQGPGSEEcNPLNMSIEAELVIEQMKEQHHrdlchlrlELEDKvrhyEKQLDDTRVASEQEQA---AMKQKYEQGVHTL 665
Cdd:COG3096   415 YQQAVQALE-KARALCGLPDLTPENAEDYLA--------AFRAK----EQQATEEVLELEQKLSvadAARRQFEKAYELV 481
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  666 EKRVSElrseiadlegqaaVLREAHHKASCRHEEEKRQLQMAfdeekAQLQEELRQEHeRELQARLQQAAESFRQERE-- 743
Cdd:COG3096   482 CKIAGE-------------VERSQAWQTARELLRRYRSQQAL-----AQRLQQLRAQL-AELEQRLRQQQNAERLLEEfc 542
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  744 -GLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALEKEELREelsehHRRELQEGREEMETECNRRVSQIEAQCQAdcEKVT 822
Cdd:COG3096   543 qRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSE-----LRQQLEQLRARIKELAARAPAWLAAQDAL--ERLR 615
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 554506543  823 EHCEQTLQSlevrhRQELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQ 877
Cdd:COG3096   616 EQSGEALAD-----SQEVTAAMQQLLEREREATVERDELAARKQALESQIERLSQ 665
PRK01156 PRK01156
chromosome segregation protein; Provisional
1218-1800 6.90e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 44.89  E-value: 6.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1218 VLKKKLKMLErlPEASSrYKVLYEDAARENSCLQE---ELRLVETRYEESLDSNKELTAEVYRLQDEMKKMEEVMETFLS 1294
Cdd:PRK01156  170 KLKDVIDMLR--AEISN-IDYLEEKLKSSNLELENikkQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSS 246
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1295 LEksyDEVKVENEELRALVLRLQGKMEKVlgraalqgdsyalweapsenlevaSDEKMLELRQTPKECTPKVVSMHHIIE 1374
Cdd:PRK01156  247 LE---DMKNRYESEIKTAESDLSMELEKN------------------------NYYKELEERHMKIINDPVYKNRNYIND 299
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1375 ECTQETQCceQGSTKLLARIKAhEIAWFHRAIKTHPEKPSAQNRVIPEGSA------ALLGLQDKHLQQEATIAELELEK 1448
Cdd:PRK01156  300 YFKYKNDI--ENKKQILSNIDA-EINKYHAIIKKLSVLQKDYNDYIKKKSRyddlnnQILELEGYEMDYNSYLKSIESLK 376
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1449 QKLQELTRNLR----ERVTALVRQKDAPSQGQKE-EELKAMMQDLQITCGEMQRKVELLRYESEKLQEENSILRNEI--- 1520
Cdd:PRK01156  377 KKIEEYSKNIErmsaFISEILKIQEIDPDAIKKElNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSvcp 456
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1521 ---TTLNEEDS--ISNLKLEELNGSQEElwqkIETIEQEKASIQTMVEKLKKQVSDLKIKN-QQLDSENIELSQKNSQNK 1594
Cdd:PRK01156  457 vcgTTLGEEKSnhIINHYNEKKSRLEEK----IREIEIEVKDIDEKIVDLKKRKEYLESEEiNKSINEYNKIESARADLE 532
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1595 EELKTLNQRLAEMLCQREEPGACTSEKWEQENASLKEELDHYKVQTSTLVSSLEAELSEVKLQthvmeqenllLKDELER 1674
Cdd:PRK01156  533 DIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRTSWLNALAVISLIDIETNRSRSNEIKKQ----------LNDLESR 602
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1675 LKQLH-RCPDLSDFQQKMSSILSYNEKLLKEKEVLSEELKSCADKLAES-SLLEHRIATMKQEQTAWEEqsesLKSQLAV 1752
Cdd:PRK01156  603 LQEIEiGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKiDNYKKQIAEIDSIIPDLKE----ITSRIND 678
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*...
gi 554506543 1753 SQAKVQNLEDVLQNVNLQMAEIESDLQVTRQEKEALKQEVMSLHRQLQ 1800
Cdd:PRK01156  679 IEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLE 726
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
1725-1909 7.28e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 7.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1725 LEHRIATMKQEQTAWEEQSESLKSQLAVSQAKVQNLEDVLQNVNLQMAEIESDLQVTRQEKEALKQEVMSLHRQLQNAID 1804
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLR 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1805 KDWVSETAPHLSGLRGQQ------RRLSWdkLDHLMN------EEPQLLCQESKRLQTVVQNTQADLTHSREKVRQLESN 1872
Cdd:COG4942   112 ALYRLGRQPPLALLLSPEdfldavRRLQY--LKYLAParreqaEELRADLAELAALRAELEAERAELEALLAELEEERAA 189
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 554506543 1873 LLPTKHQKQLnqpcTVKSTEQEKLTLKRECEQSQKEQ 1909
Cdd:COG4942   190 LEALKAERQK----LLARLEKELAELAAELAELQQEA 222
COG5022 COG5022
Myosin heavy chain [General function prediction only];
810-1299 7.49e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 44.68  E-value: 7.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  810 IEAQCQADCEKVTEHCEQTLQSLEVRHRQ---ELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRERATAAAM 886
Cdd:COG5022   940 IDLEEGPSIEYVKLPELNKLHEVESKLKEtseEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLK 1019
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  887 KQEQEILERTYKDRLNILSTERKQLLQDLKDLQNASESQHGLLSGQILELKRSQERELRDQGQaLCQTGVSEQLASqqle 966
Cdd:COG5022  1020 ELPVEVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQ-LYQLESTENLLK---- 1094
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  967 RLRVEHEQERREMTGKLAALESAHRASLERADQEKaEMSTEICRLQNTVKDMQQAASLLMLQGGC---QATAGEEAEGDG 1043
Cdd:COG5022  1095 TINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQ-EISKFLSQLVNTLEPVFQKLSVLQLELDGlfwEANLEALPSPPP 1173
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1044 AMSLLQQ---GEQLLEENGDVLISLQRAHEHAVKENAKMATEISRLQQRLKKLE-PGSVISSCLEEGTSEISGSSREQVE 1119
Cdd:COG5022  1174 FAALSEKrlyQSALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLIsEGWVPTEYSTSLKGFNNLNKKFDTP 1253
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1120 PIMKQgPATKHFLSDL-GDHEARDLASTGTSSVQRQECKT----EASEASLDCFS-ELENSED-----TRTESWDLKSQI 1188
Cdd:COG5022  1254 ASMSN-EKLLSLLNSIdNLLSSYKLEEEVLPATINSLLQYinvgLFNALRTKASSlRWKSATEvnynsEELDDWCREFEI 1332
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543 1189 SQLREQLTVLRadcdRASERKQDLLFDISVLKKKLKMLERL-PEASSRYKVLYEDAARENSCLQEELRLVET-RYEESLD 1266
Cdd:COG5022  1333 SDVDEELEELI----QAVKVLQLLKDDLNKLDELLDACYSLnPAEIQNLKSRYDPADKENNLPKEILKKIEAlLIKQELQ 1408
                         490       500       510
                  ....*....|....*....|....*....|...
gi 554506543 1267 SNKELTAEVYRLQDEMKKMEEVMetfLSLEKSY 1299
Cdd:COG5022  1409 LSLEGKDETEVHLSEIFSEEKSL---ISLDRNS 1438
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
403-1148 8.42e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.72  E-value: 8.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   403 EVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRQEREQMLQQ---VGKQRVELEQEIQKAKTEENY---IRDRLALS 476
Cdd:pfam15921   60 ELDSPRKIIAYPGKEHIERVLEEYSHQVKDLQRRLNESNELHEKQkfyLRQSVIDLQTKLQEMQMERDAmadIRRRESQS 139
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   477 LKE-NNRLETEL--LENAEKLAE---YESLTQ-----KLQRSLENVLAEKFG---DLDPSSAEFFLQEERLAQMR----- 537
Cdd:pfam15921  140 QEDlRNQLQNTVheLEAAKCLKEdmlEDSNTQieqlrKMMLSHEGVLQEIRSilvDFEEASGKKIYEHDSMSTMHfrslg 219
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   538 NEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPLKNSLSEELDGHSGGIEP------------DQGPGSEECNPLNMSI 605
Cdd:pfam15921  220 SAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQliseheveitglTEKASSARSQANSIQS 299
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   606 EAELVIEQMKEQHHRDLCHLRlELEDKVRHYEKQLDDTrvaseqeqaamKQKYEQGVHTLEKRVSELRSEIADLegqaav 685
Cdd:pfam15921  300 QLEIIQEQARNQNSMYMRQLS-DLESTVSQLRSELREA-----------KRMYEDKIEELEKQLVLANSELTEA------ 361
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   686 lreahhkascrhEEEKRQLQMAFDEEKAQLQEELRQEHERELQARLQQAAESFRQEREglaqaAWTEEKVRGLEQSYQEQ 765
Cdd:pfam15921  362 ------------RTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRD-----TGNSITIDHLRRELDDR 424
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   766 LLSLEEKHALEKEELREELSEHHRR--ELQEGREEMEtecnrRVSQIEAQCQADCE---KVTEHCEQTLQSLEVRHRQeL 840
Cdd:pfam15921  425 NMEVQRLEALLKAMKSECQGQMERQmaAIQGKNESLE-----KVSSLTAQLESTKEmlrKVVEELTAKKMTLESSERT-V 498
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   841 RDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEaLQRerataaaMKQEQEILE--RTYKDRLNILSTERKQLLQDLK-D 917
Cdd:pfam15921  499 SDLTASLQEKERAIEATNAEITKLRSRVDLKLQE-LQH-------LKNEGDHLRnvQTECEALKLQMAEKDKVIEILRqQ 570
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   918 LQNASE--SQHGLLSGQILELKRSQERELRDQgqalcqtgvseQLASQQLERLRVEHEQERREMTGKLAALE-------- 987
Cdd:pfam15921  571 IENMTQlvGQHGRTAGAMQVEKAQLEKEINDR-----------RLELQEFKILKDKKDAKIRELEARVSDLElekvklvn 639
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   988 --SAHRASLERADQEKAEMSTEICRLQNTVKDMQQAASLLMLQGGCQATAGEEAEGDGAMSlLQQGEQLLEENGDVLISL 1065
Cdd:pfam15921  640 agSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQ-LKSAQSELEQTRNTLKSM 718
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1066 QRAHEHAVKENAKMATEISRLQQRLKKLEpgsvisscleegtseisgSSREQVEPIMKQGPATKHFLSDLGDHEARDLAS 1145
Cdd:pfam15921  719 EGSDGHAMKVAMGMQKQITAKRGQIDALQ------------------SKIQFLEEAMTNANKEKHFLKEEKNKLSQELST 780

                   ...
gi 554506543  1146 TGT 1148
Cdd:pfam15921  781 VAT 783
mukB PRK04863
chromosome partition protein MukB;
339-1002 9.18e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.56  E-value: 9.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  339 LTELTLALENELlvtknGIHQAALASFKAEIRHLLERVDQVVRE--KEKLRSDLDKAEKLKSLMASEV--DDHHAAIERR 414
Cdd:PRK04863  454 ATEELLSLEQKL-----SVAQAAHSQFEQAYQLVRKIAGEVSRSeaWDVARELLRRLREQRHLAEQLQqlRMRLSELEQR 528
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  415 --NEYNLRKLDEEYKERI------AALKNELRQEREQMLQ-------QVGKQRVELEQEIQKAKTEENYIRDRLALSLKE 479
Cdd:PRK04863  529 lrQQQRAERLLAEFCKRLgknlddEDELEQLQEELEARLEslsesvsEARERRMALRQQLEQLQARIQRLAARAPAWLAA 608
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  480 NNRLETELLENAEKLAEYESLTQKLQRSLEnvlaekfgdldpssaefflQEERLAQMRNEYEQQCRLLQDQVDELQ---- 555
Cdd:PRK04863  609 QDALARLREQSGEEFEDSQDVTEYMQQLLE-------------------RERELTVERDELAARKQALDEEIERLSqpgg 669
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  556 SELEEYQAQ----GRVLrlplknsLSEELDGhsggIEPDQGPG-SEECNPLNMSI---EAELVIEQMKEQhhrDLCHLRL 627
Cdd:PRK04863  670 SEDPRLNALaerfGGVL-------LSEIYDD----VSLEDAPYfSALYGPARHAIvvpDLSDAAEQLAGL---EDCPEDL 735
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  628 ELedkVRHYEKQLDDTRVASEQEQAAMKQKYEQgvhtLEKRVSELRSE-----------IADLEGQAAVLREAHHKASCR 696
Cdd:PRK04863  736 YL---IEGDPDSFDDSVFSVEELEKAVVVKIAD----RQWRYSRFPEVplfgraarekrIEQLRAEREELAERYATLSFD 808
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  697 HEEEKRQLQ-----------MAFDEEKAQLQEELRQEHeRELQARLQQAAESFRQEREGLAQAawtEEKVRGLEQSYQEQ 765
Cdd:PRK04863  809 VQKLQRLHQafsrfigshlaVAFEADPEAELRQLNRRR-VELERALADHESQEQQQRSQLEQA---KEGLSALNRLLPRL 884
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  766 LLSLEEKHALEKeelreelsehhrRELQEGREEME------TECNRRVSQIEAQC---QADCEKVTEHCEQTLQSLEVRH 836
Cdd:PRK04863  885 NLLADETLADRV------------EEIREQLDEAEeakrfvQQHGNALAQLEPIVsvlQSDPEQFEQLKQDYQQAQQTQR 952
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  837 RQELR-DLLDQHLEERSQWEFEKD-ELTQECTDAQEQLKEALQRERATAAAMKQEQeileRTYKDRLnilsTERKQLLQD 914
Cdd:PRK04863  953 DAKQQaFALTEVVQRRAHFSYEDAaEMLAKNSDLNEKLRQRLEQAEQERTRAREQL----RQAQAQL----AQYNQVLAS 1024
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  915 LKDLQNASESQHGLLsgqilelkrsqERELRDQGQALCQtGVSEQLASQ----------------QLERLRVEHEQERRE 978
Cdd:PRK04863 1025 LKSSYDAKRQMLQEL-----------KQELQDLGVPADS-GAEERARARrdelharlsanrsrrnQLEKQLTFCEAEMDN 1092
                         730       740
                  ....*....|....*....|....
gi 554506543  979 MTGKLAALESAHRASLERADQEKA 1002
Cdd:PRK04863 1093 LTKKLRKLERDYHEMREQVVNAKA 1116
PTZ00121 PTZ00121
MAEBL; Provisional
374-900 1.04e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 1.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  374 ERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRQEREQMLQQVGKQRV 453
Cdd:PTZ00121 1290 KKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAA 1369
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  454 ELEQEIQKAKTEENYIRDRLALSLKENNRLETELLENAEKLAEYESLTQKLQRSLENVLAEKFGDLDPSSAEfflqEERL 533
Cdd:PTZ00121 1370 EKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAE----EAKK 1445
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  534 AQMRNEYEQQCRllqdQVDELQSELEEYQAQGRVLRLPLKNSLSEELDGHSGGIEPDQGPGSEECNPLNMSIEAELVIEQ 613
Cdd:PTZ00121 1446 ADEAKKKAEEAK----KAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEA 1521
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  614 MKEQHHRDLCHLRLELEDKVRHYEKQLDDTRVASEQEQAAMKQKYEQGVHTLEKRVSELRSeiADLEGQAAVLREAHHKA 693
Cdd:PTZ00121 1522 KKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRK--AEEAKKAEEARIEEVMK 1599
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  694 SCRHEEEKRQLQMAFDEEKAQLQEELRQEHE--------RELQARLQQAAESFRQEREglaqaawtEEKVRgleqsyQEQ 765
Cdd:PTZ00121 1600 LYEEEKKMKAEEAKKAEEAKIKAEELKKAEEekkkveqlKKKEAEEKKKAEELKKAEE--------ENKIK------AAE 1665
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  766 LLSLEEKHALEKEELREELSEHHRRELQEGREEMETECNRRVSQIEAQCQADCEKVTEHCEQTLQSLEVRHRQELRDllD 845
Cdd:PTZ00121 1666 EAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED--K 1743
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 554506543  846 QHLEERSQWEFEKDELTQECTDAQEQLKEALQRERATAAAMKQEQEILERTYKDR 900
Cdd:PTZ00121 1744 KKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
446-765 1.07e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.96  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   446 QQVGKQRVELEQEIQKAKTEENYIRDRLALSLKENNRlETELLENAEKLAEYESLTQKLQRSLENVLaekfgdldpssae 525
Cdd:pfam17380  289 QQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKAR-QAEMDRQAAIYAEQERMAMERERELERIR------------- 354
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   526 fflQEERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPLKNSLSEELDGHSGGIEPDQGPGSEECNPLNMSI 605
Cdd:pfam17380  355 ---QEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEE 431
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   606 EAELVIEQMKEQHHRDLCHLRLEledkvrHYEKQLDDTRVASEQEQAAMKQKYEQGVHTLEKRVSELRSEIADLEGQA-- 683
Cdd:pfam17380  432 ARQREVRRLEEERAREMERVRLE------EQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEErk 505
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   684 -AVLREAHHKASCRHEEEKRQLQMAFDEEKAQLQEELRQEHERELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSY 762
Cdd:pfam17380  506 qAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIVESE 585

                   ...
gi 554506543   763 QEQ 765
Cdd:pfam17380  586 KAR 588
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
1162-1673 1.29e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.94  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1162 EASLDCFSELEnsEDTRTESWDLKSQISQ---LREQLTVLRADCDRASERKQDLLFDISVLKK--------KLKMLERLP 1230
Cdd:pfam05483  264 EESRDKANQLE--EKTKLQDENLKELIEKkdhLTKELEDIKMSLQRSMSTQKALEEDLQIATKticqlteeKEAQMEELN 341
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1231 EASSRYKVLYEDAARENSCLQEELRLVETRYEESLDSNKELTAEVYRLQDEMKKMEevmetflsleKSYDEVKVENEELR 1310
Cdd:pfam05483  342 KAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMT----------KFKNNKEVELEELK 411
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1311 alvlrlqgkmeKVLGRAALQGDSYALWEAPSENLEVASDEKMLELRQTPKECtpkvvsmhHIIEECTQETQCCEQGSTKL 1390
Cdd:pfam05483  412 -----------KILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEI--------HDLEIQLTAIKTSEEHYLKE 472
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1391 LarikaheiawfhRAIKTHPEKPSAQNRVIPEGSAALLgLQDKHLQQEATIAELELEKQK-------------------L 1451
Cdd:pfam05483  473 V------------EDLKTELEKEKLKNIELTAHCDKLL-LENKELTQEASDMTLELKKHQediinckkqeermlkqienL 539
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1452 QELTRNLRERVTALVR----------------QKDAPSQGQKEEELKAMMQDLQITCGEMQRKVELLRYESEKLQEENSI 1515
Cdd:pfam05483  540 EEKEMNLRDELESVREefiqkgdevkckldksEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKA 619
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1516 LRNEITTLNEEDSISNLKLEELNGSQEELWQKIEtieqekasiqTMVEKLKKQVSDLKIKNQQLDSE----NIELSQKNS 1591
Cdd:pfam05483  620 LKKKGSAENKQLNAYEIKVNKLELELASAKQKFE----------EIIDNYQKEIEDKKISEEKLLEEvekaKAIADEAVK 689
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1592 QNKEELKTLNQRLAEMLCQREEPGACTSEKWEQENASL------KEELDHYKVQTSTLVSSLEAELSEVKLQTHVMEQEN 1665
Cdd:pfam05483  690 LQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELglyknkEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEK 769

                   ....*...
gi 554506543  1666 LLLKDELE 1673
Cdd:pfam05483  770 EKLKMEAK 777
PTZ00121 PTZ00121
MAEBL; Provisional
377-1123 1.55e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 1.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  377 DQVVREKEKLRSDLDKAEKLKSLMASEV--DDHHAAIERRNEYNLRK-------LDEEYKERIAALKNELRQEREQMLQQ 447
Cdd:PTZ00121 1039 DDVLKEKDIIDEDIDGNHEGKAEAKAHVgqDEGLKPSYKDFDFDAKEdnradeaTEEAFGKAEEAKKTETGKAEEARKAE 1118
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  448 VGKQRVELEQEIQKAKTEENYIRDRLALSLKENNRLE-TELLENAEKL-----AEYESLTQKLQRSLENVLAE---KFGD 518
Cdd:PTZ00121 1119 EAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEiARKAEDARKAeearkAEDAKKAEAARKAEEVRKAEelrKAED 1198
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  519 LDPSSAEFFLQEERLAQMRNEYEQQCRLLQ-DQVDELQSELEEYQAQGRVLRLPLKNSLSEELDGH----SGGIEPDQGP 593
Cdd:PTZ00121 1199 ARKAEAARKAEEERKAEEARKAEDAKKAEAvKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHfarrQAAIKAEEAR 1278
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  594 GSEECNPLNMSIEAElviEQMKEQHHRDLCHLRLELEDKVRHYE---KQLDDTRVASEQEQAAMKQKYEQGVHTLEKRVS 670
Cdd:PTZ00121 1279 KADELKKAEEKKKAD---EAKKAEEKKKADEAKKKAEEAKKADEakkKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAA 1355
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  671 ELRSEIADLEGQAAVLREAHHKASCRHEEEKRQLQMAFDEEKAQLQEELRQEHERELQARLQQAAESFRQEREGLAQAaw 750
Cdd:PTZ00121 1356 ADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKA-- 1433
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  751 TEEKVRGLEQSYQEQLLSLEEKHALEKEELREELSEHHRRELQEGREEMETECNRRVSQIEAQCQADCEKVTEHCEQTLQ 830
Cdd:PTZ00121 1434 DEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKAD 1513
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  831 SLEVRHRQELRDLLDQHLEERSQWEFEKDELTQECTDAQ--EQLKEALQRERATAAAMKQEQEILERTYKDRLNILSTER 908
Cdd:PTZ00121 1514 EAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKkaEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  909 KQLLQDLKDLQNASESQHgLLSGQILELKRSQERELRDQGQALCQTGVSEQLASQQLERLRVEHEQE--RREMTGKLAAL 986
Cdd:PTZ00121 1594 IEEVMKLYEEEKKMKAEE-AKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENkiKAAEEAKKAEE 1672
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  987 ESAHRASLERADQEKAEMSTEICRLQNTVKDMQQAASLLM--LQGGCQATAGEEAEGDGAMSLLQQGEQlleengdvliS 1064
Cdd:PTZ00121 1673 DKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAeeKKKAEELKKAEEENKIKAEEAKKEAEE----------D 1742
                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 554506543 1065 LQRAHEHAVKENAKMATEISRLQQRLKKLEPGSVISSCLEEGTSEISGSSREQVEPIMK 1123
Cdd:PTZ00121 1743 KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIK 1801
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
530-1334 1.78e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.57  E-value: 1.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   530 EERLAQMRNEYEQQCRLLQDQVDELQSELEEYQ------AQGRVLRLPLKNSLSEELDGHSGGIEPDQGPGSEECNPLNM 603
Cdd:pfam15921   91 QRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQmerdamADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNT 170
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   604 SIEAelvIEQMKEQHHRDLCHLRLELEDKVRHYEKQLDDTRVASEQEQAAMKQKYEQGVHTLEKRVSELRSEIADLEGQA 683
Cdd:pfam15921  171 QIEQ---LRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQL 247
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   684 AVLREahhkascrheEEKRQLQMAFDEEKAQLqEELRQEHERELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQ 763
Cdd:pfam15921  248 EALKS----------ESQNKIELLLQQHQDRI-EQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYM 316
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   764 EQLLSLEEKHALEkeelreelsehhRRELQEGREEMETecnrRVSQIEAQCQADCEKVTEHceqtlqslevrhrqelrdl 843
Cdd:pfam15921  317 RQLSDLESTVSQL------------RSELREAKRMYED----KIEELEKQLVLANSELTEA------------------- 361
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   844 ldqhleersqwEFEKDELTQECTDAQEQLKEAL----QRERATAAAMKQEQEILERTYKDRLNIlsterKQLLQDLKDLQ 919
Cdd:pfam15921  362 -----------RTERDQFSQESGNLDDQLQKLLadlhKREKELSLEKEQNKRLWDRDTGNSITI-----DHLRRELDDRN 425
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   920 NASESQHGLLSGQILELKRSQERELRD-QGQALCQTGVSEQLAsqQLERLRVEHEQERREMTGKLAALESAHR------A 992
Cdd:pfam15921  426 MEVQRLEALLKAMKSECQGQMERQMAAiQGKNESLEKVSSLTA--QLESTKEMLRKVVEELTAKKMTLESSERtvsdltA 503
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   993 SLERADQEKAEMSTEICRLQNTV----KDMQ----QAASLLMLQGGCQATAGEEAEGDGAMSLLQQG----EQLLEENGD 1060
Cdd:pfam15921  504 SLQEKERAIEATNAEITKLRSRVdlklQELQhlknEGDHLRNVQTECEALKLQMAEKDKVIEILRQQienmTQLVGQHGR 583
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1061 VLISLQrahehavKENAKMATEISRLQQRLKKLEP-GSVISSCLEEGTSEISGSSREQVEpIMKQGPATKHFLSDLGDHE 1139
Cdd:pfam15921  584 TAGAMQ-------VEKAQLEKEINDRRLELQEFKIlKDKKDAKIRELEARVSDLELEKVK-LVNAGSERLRAVKDIKQER 655
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1140 ARDLASTGTSsvqRQECKTEASEASLDCFSELENSEDTRTESWDLK-------SQISQLREQLTVLRADCDRASERKQDL 1212
Cdd:pfam15921  656 DQLLNEVKTS---RNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKmqlksaqSELEQTRNTLKSMEGSDGHAMKVAMGM 732
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1213 LFDIS-------VLKKKLKMLERLPEASSRYKVLYEDaarENSCLQEELRLVETRYEESLDSNKELTAEVYRLQDEMKKM 1285
Cdd:pfam15921  733 QKQITakrgqidALQSKIQFLEEAMTNANKEKHFLKE---EKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANM 809
                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 554506543  1286 EEVMETfLSLEKSYDEVKVENEELRALVLRLQgkmeKVLGRAALQGDSY 1334
Cdd:pfam15921  810 EVALDK-ASLQFAECQDIIQRQEQESVRLKLQ----HTLDVKELQGPGY 853
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
710-1093 1.94e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.42  E-value: 1.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   710 EEKAQLQEELRQEHERELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQEQllsLEEKHALEKEELREELSEHHR 789
Cdd:TIGR00618  200 TLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQ---LKKQQLLKQLRARIEELRAQE 276
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   790 RELQEGREEMETECNRRVSQIEAQCQADCEKVTEHCEQTLQSLEVRHRQEL---RDLLDQHLEERSQWEFEKDELTQE-- 864
Cdd:TIGR00618  277 AVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLmkrAAHVKQQSSIEEQRRLLQTLHSQEih 356
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   865 ---CTDAQEQLKEALQRERATAAAMKQEQEILErTYKDRLNILSTERKQlLQDLKDLQNASESQHGLLSGQILELKRSQE 941
Cdd:TIGR00618  357 irdAHEVATSIREISCQQHTLTQHIHTLQQQKT-TLTQKLQSLCKELDI-LQREQATIDTRTSAFRDLQGQLAHAKKQQE 434
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   942 RELRDqgQALCQTGVSEQLASQQLE-RLRVEHEQERREMTGKLAALESAHRASLERA---DQEKAEMSTEICRLQNTVKD 1017
Cdd:TIGR00618  435 LQQRY--AELCAAAITCTAQCEKLEkIHLQESAQSLKEREQQLQTKEQIHLQETRKKavvLARLLELQEEPCPLCGSCIH 512
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 554506543  1018 MQQAASLLMLQGGCQatageeaegdgamSLLQQGEQLLEENGDVLISLQRAHEHAVKENAKMATEISRLQQRLKKL 1093
Cdd:TIGR00618  513 PNPARQDIDNPGPLT-------------RRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSIL 575
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
531-765 2.20e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 2.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  531 ERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLpLKNSLSEELDghsggiepdqgpgseecnplNMSIEAELV 610
Cdd:COG4913   613 AALEAELAELEEELAEAEERLEALEAELDALQERREALQR-LAEYSWDEID--------------------VASAEREIA 671
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  611 ieqmkeqhhrdlchlrlELEDKVRHYEKQLDDTRVASEQEQAamkqkyeqgvhtLEKRVSELRSEIADLEGQAAVLREAH 690
Cdd:COG4913   672 -----------------ELEAELERLDASSDDLAALEEQLEE------------LEAELEELEEELDELKGEIGRLEKEL 722
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 554506543  691 HKASCRHEEEKRQLQMAFDEEKAQLQEELRQEHERELQ-ARLQQAAESFRQEREGLAQAAW-TEEKVRGLEQSYQEQ 765
Cdd:COG4913   723 EQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGdAVERELRENLEERIDALRARLNrAEEELERAMRAFNRE 799
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
428-564 2.24e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  428 ERIAALKNELRQEREQmLQQVGKQRVELEQEIQKAKTEENYIRDRLALSLKENNRLETELLENAEKLAEYESLTQKLQRS 507
Cdd:COG4942    20 DAAAEAEAELEQLQQE-IAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  508 LEN---------VLAEKFGDLDPS----SAEFFLQEERLAQMRNEYEQQcrlLQDQVDELQSELEEYQAQ 564
Cdd:COG4942    99 LEAqkeelaellRALYRLGRQPPLalllSPEDFLDAVRRLQYLKYLAPA---RREQAEELRADLAELAAL 165
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
656-1094 2.32e-03

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 42.97  E-value: 2.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  656 QKYEQGVHTLEKRVSELRSEIADLEGQAAVLREAHHKASCRHEEEKRQLQMAFDEEKAQLQEELRQEHERELQARLQQAA 735
Cdd:COG5278    79 EPYEEARAEIDELLAELRSLTADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRARL 158
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  736 ESFRQEREGLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALEKEELREELSEHHRRELQEGREEMETECNRRVSQIEAQCQ 815
Cdd:COG5278   159 LLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAAL 238
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  816 ADCEKVTEHCEQTLQSLEVRHRQELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRERATAAAMKQEQEILER 895
Cdd:COG5278   239 ALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAA 318
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  896 TYKDRLNILSTERKQLLQDLKDLQNASESQHGLLSGQILELKRSQERELRDQGQALCQTGVSEQLASQQLERLRVEHEQE 975
Cdd:COG5278   319 AAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAA 398
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  976 RREMTGKLAALESAHRASLERADQEKAEMSTEICRLQNTVKDMQQAASLLMLQGGCQATAGEEAEGDGAMSLLQQGEQLL 1055
Cdd:COG5278   399 AAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALA 478
                         410       420       430
                  ....*....|....*....|....*....|....*....
gi 554506543 1056 EENGDVLISLQRAHEHAVKENAKMATEISRLQQRLKKLE 1094
Cdd:COG5278   479 AAAAALAEAEAAAALAAAAALSLALALAALLLAAAEAAL 517
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
531-1323 2.72e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.74  E-value: 2.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   531 ERLAQMRNEYEQQCRLLQDQVD------ELQSELEEYQAQGRVLRLplkNSLSEELDGHSGGIEPDQgpgsEECNplnmS 604
Cdd:TIGR02168  189 DRLEDILNELERQLKSLERQAEkaerykELKAELRELELALLVLRL---EELREELEELQEELKEAE----EELE----E 257
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   605 IEAELvieQMKEQHHRDLCHLRLELEDKVRHYEKQLDDTrVASEQEQAAMKQKYEQGVHTLEKRVSELRSEIADLEGQAA 684
Cdd:TIGR02168  258 LTAEL---QELEEKLEELRLEVSELEEEIEELQKELYAL-ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLD 333
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   685 VLREAHHKAscrhEEEKRQLQMAFDEEKAQLQEElrQEHERELQARLQQAAESFRQEREGLAQAAWTEEKVRGLEQSYQE 764
Cdd:TIGR02168  334 ELAEELAEL----EEKLEELKEELESLEAELEEL--EAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEA 407
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   765 QLLSLEEKHA---LEKEELREELSEHHRRELQEGREEMETE------CNRRVSQIEAQCQADCEKVTEHCEQTLQSL-EV 834
Cdd:TIGR02168  408 RLERLEDRRErlqQEIEELLKKLEEAELKELQAELEELEEEleelqeELERLEEALEELREELEEAEQALDAAERELaQL 487
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   835 RHRQELRDLLDQHLEERS----QWEFEKDELTQ---------ECTDAQEQLKEALQRERATAAAM------KQEQEILER 895
Cdd:TIGR02168  488 QARLDSLERLQENLEGFSegvkALLKNQSGLSGilgvlseliSVDEGYEAAIEAALGGRLQAVVVenlnaaKKAIAFLKQ 567
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   896 TYKDRLNIL-----------STERKQL------LQDLKDLQNASESQHGLLSG------------QILELKRSQERELR- 945
Cdd:TIGR02168  568 NELGRVTFLpldsikgteiqGNDREILkniegfLGVAKDLVKFDPKLRKALSYllggvlvvddldNALELAKKLRPGYRi 647
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   946 --DQGQAL----CQTGVSEQLASQQLERLR--VEHEQERREMTGKLAALESAhrasLERADQEKAEMSTEICRLQNTVKD 1017
Cdd:TIGR02168  648 vtLDGDLVrpggVITGGSAKTNSSILERRReiEELEEKIEELEEKIAELEKA----LAELRKELEELEEELEQLRKELEE 723
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1018 MQQAASLL--MLQGGCQATAGEEAEGDGAMSLLQQGEQLLEENGDVLISLQRAHEHAVKENAKMATEISRLQQRLKKLEP 1095
Cdd:TIGR02168  724 LSRQISALrkDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1096 GSVISSCLEEGTSEISGSSREQVEPIMKQGPATKHFLSDLgDHEARDLASTGTSSVQRQECKTEASEASLDCFSELENSE 1175
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL-EEQIEELSEDIESLAAEIEELEELIEELESELEALLNER 882
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1176 DTRTEswdlksQISQLREQLTVLRADCDRASERKQDLLFDISVLKKKL-KMLERLPEASSRYKVLYEDAAREnscLQEEL 1254
Cdd:TIGR02168  883 ASLEE------ALALLRSELEELSEELRELESKRSELRRELEELREKLaQLELRLEGLEVRIDNLQERLSEE---YSLTL 953
                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 554506543  1255 RLVETRYEESLDSNKELTAEVYRLQDEMKKMEEV----METFLSLEKSYDEVKVENEELRALVLRLQGKMEKV 1323
Cdd:TIGR02168  954 EEAEALENKIEDDEEEARRRLKRLENKIKELGPVnlaaIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
706-942 3.77e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  706 MAFDEEKAQLQEELrQEHERELQARLQQAAESFRQEREGLAQAAWTEEKVRGLE---QSYQEQLLSLEEKHALEKEElre 782
Cdd:COG4942    16 AAQADAAAEAEAEL-EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALArriRALEQELAALEAELAELEKE--- 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  783 elsehhRRELQEGREEMETECNRRVSQIEAQCQADCEKVTEHCEQTLQSLEVRHR-----QELRDLLDQHLEERSQWEFE 857
Cdd:COG4942    92 ------IAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYlkylaPARREQAEELRADLAELAAL 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  858 KDELTQEcTDAQEQLKEALQRERATAAAMKQEQEILertykdrLNILSTERKQLLQDLKDLQNASESQHGLLSGQILELK 937
Cdd:COG4942   166 RAELEAE-RAELEALLAELEEERAALEALKAERQKL-------LARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237

                  ....*
gi 554506543  938 RSQER 942
Cdd:COG4942   238 AAAER 242
LCD1 pfam09798
DNA damage checkpoint protein; This is a family of proteins which regulate checkpoint kinases. ...
1474-1583 4.30e-03

DNA damage checkpoint protein; This is a family of proteins which regulate checkpoint kinases. In Schizosaccharomyces pombe this protein is called Rad26 and in Saccharomyces cerevisiae it is called LCD1.


Pssm-ID: 462906  Cd Length: 615  Bit Score: 41.92  E-value: 4.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1474 QGQKEEELKAMMQDLQITCGEMQRKVELLRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQ 1553
Cdd:pfam09798   10 QQEKEKELEKLKNSYEELKSSHEEELEKLKQEVQKLEDEKKFLLNELRSLSATSPASSQSHETDTDDSSSVSLKKRKIEE 89
                           90       100       110
                   ....*....|....*....|....*....|
gi 554506543  1554 EKAsiqtmvEKLKKQVsdLKIKNQQLDSEN 1583
Cdd:pfam09798   90 STA------ESLKQKY--IRLQNNRIVDET 111
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
378-960 4.33e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.26  E-value: 4.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   378 QVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRQEREQMlQQVGKQRVELEQ 457
Cdd:TIGR00618  264 QLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKR-AAHVKQQSSIEE 342
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   458 EIQKAKT---EENYIRDR--LALSLKENNRLETELLENAEKLAE-YESLTQKLQ--RSLENVLAEKFGDLDPSSAEFFLQ 529
Cdd:TIGR00618  343 QRRLLQTlhsQEIHIRDAheVATSIREISCQQHTLTQHIHTLQQqKTTLTQKLQslCKELDILQREQATIDTRTSAFRDL 422
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   530 EERLAQMRNEYEQQCRLLQDQVDELQSELEEYQAQGRVLRLPLK--NSLSEELDGHSGGIEPDQGPGSEECNPLNMSIEA 607
Cdd:TIGR00618  423 QGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQslKEREQQLQTKEQIHLQETRKKAVVLARLLELQEE 502
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   608 ELVIEQMKEQHHRDL---------CHLRLELEDKVRHYEKQLDDT---------RVASEQEQAAMKQKYEQGVHTLEKRV 669
Cdd:TIGR00618  503 PCPLCGSCIHPNPARqdidnpgplTRRMQRGEQTYAQLETSEEDVyhqltserkQRASLKEQMQEIQQSFSILTQCDNRS 582
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   670 SE----LRSEIADLEGQAAVLREAHHKASCRHEEEKRQLQMAFDEEKAQLQEELRQEHERELQARLQQAAESFRQEREGL 745
Cdd:TIGR00618  583 KEdipnLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVRE 662
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   746 AQAAWTEEKvrglEQSYQEQLLSLEEKHALEKEELREELSEHHRRELQEGREEMETECNRRVSQIEAQCQADCEKVTEHC 825
Cdd:TIGR00618  663 HALSIRVLP----KELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAARE 738
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   826 EQTLQSLevRHRQELRDLLDQHLEERSQWEFEKDELTQECTDAQEQLKEALQRERATAAA----MKQEQEILERTYKDRL 901
Cdd:TIGR00618  739 DALNQSL--KELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEdthlLKTLEAEIGQEIPSDE 816
                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 554506543   902 NILSTERKQLLQDLKDLQNASESQHGLLSGQILELKRSQERELRDQGQALCQTGVSEQL 960
Cdd:TIGR00618  817 DILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLS 875
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1430-1657 4.43e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.36  E-value: 4.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1430 LQDKHLQQEATIAELELEKQKLQELTRNLRERVTALVR--QKDAPSQGQKEEELKAMMQDLQITCGEMQRKVELLRYESE 1507
Cdd:TIGR02169  260 ISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGelEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIE 339
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1508 KLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQTMVEKLKKQVSDLKIKNQQLDSENIELS 1587
Cdd:TIGR02169  340 ELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLS 419
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 554506543  1588 QKNSQNKEELKTLNQRLAEMLCQREEPGACTSEKwEQENASLKEELDHYKVQ---TSTLVSSLEAELSEVKLQ 1657
Cdd:TIGR02169  420 EELADLNAAIAGIEAKINELEEEKEDKALEIKKQ-EWKLEQLAADLSKYEQElydLKEEYDRVEKELSKLQRE 491
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
1509-1800 4.53e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.93  E-value: 4.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1509 LQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQTMVEKLKKQvsdLKIKNQQLDSENIELSQ 1588
Cdd:TIGR04523   73 SNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQ---KKENKKNIDKFLTEIKK 149
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1589 KNSqnkeELKTLNQRLAEMLCQRE----EPGACTSEKWEQENASLKEELDHYKVQTSTLV--------SSLEAELSEVKL 1656
Cdd:TIGR04523  150 KEK----ELEKLNNKYNDLKKQKEelenELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNlkkkiqknKSLESQISELKK 225
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1657 QTHVMEQENLLLKDELERLKQlhrcpDLSDFQQKMSSILSYNEKLLKEKEVLSEELKSCADKLAEsslLEHRIATMKQEQ 1736
Cdd:TIGR04523  226 QNNQLKDNIEKKQQEINEKTT-----EISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKE---LEKQLNQLKSEI 297
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 554506543  1737 TAWEEQSES-----LKSQLAVSQAKVQNLEDVLQNVNLQMAEIESDLQVTRQEKEALKQEVMSLHRQLQ 1800
Cdd:TIGR04523  298 SDLNNQKEQdwnkeLKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELE 366
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
1436-1873 6.86e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 6.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1436 QQEATIAELELEKQKLQELTRNLRERVTALVRQKDapSQGQKEEELKAMMQDLQITCGEMQRKVELLRYESEKLQEENSI 1515
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRD--KLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1516 LRNEITTLNEEDSISNLKLEELNGSQEELWQKIETIEQEKASIQTMVEKLKKQVSDLKIKNQQLDSENIELSQKNSQNKE 1595
Cdd:TIGR02169  397 LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKE 476
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1596 ELKTLNQRLAEMlcQRE----EPGACTSEKWEQENASLKEELDhykvQTSTLVSSLEAELSEVK--------------LQ 1657
Cdd:TIGR02169  477 EYDRVEKELSKL--QRElaeaEAQARASEERVRGGRAVEEVLK----ASIQGVHGTVAQLGSVGeryataievaagnrLN 550
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1658 THVMEQENL------LLKDE---------LERLKQLHRCP-------------DLSDFQQKMSSILSY------------ 1697
Cdd:TIGR02169  551 NVVVEDDAVakeaieLLKRRkagratflpLNKMRDERRDLsilsedgvigfavDLVEFDPKYEPAFKYvfgdtlvvedie 630
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1698 ---------------------------------------------NEKLLKEKEVLSEELKSCADKLAES---------- 1722
Cdd:TIGR02169  631 aarrlmgkyrmvtlegelfeksgamtggsraprggilfsrsepaeLQRLRERLEGLKRELSSLQSELRRIenrldelsqe 710
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1723 -SLLEHRIATMKQEQTAWEEQSESLKSQLAVSQAKVQNLEDVLQNVNLQMAEIESDLQVTRQEKEALKQEVMSLHR---- 1797
Cdd:TIGR02169  711 lSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEArlsh 790
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1798 ----QLQNAIDK--DWVSETAPHLSGLRGQQRRLSWDK--LDHLMNEEPQLL----------CQESKRLQTVVQNTQADL 1859
Cdd:TIGR02169  791 sripEIQAELSKleEEVSRIEARLREIEQKLNRLTLEKeyLEKEIQELQEQRidlkeqiksiEKEIENLNGKKEELEEEL 870
                          570
                   ....*....|....
gi 554506543  1860 THSREKVRQLESNL 1873
Cdd:TIGR02169  871 EELEAALRDLESRL 884
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
629-733 7.68e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.38  E-value: 7.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  629 LEDKVRHYEKQLDDTRVASEQEQAAMKQKYEQGVHTLEKRVSELRSEIADLEGQAAVLREAHHKASCRHEEEKRQLQM-- 706
Cdd:COG2433   382 LEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEERRei 461
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 554506543  707 -------AFDEEKAQLQEELRQEHER--ELQARLQQ 733
Cdd:COG2433   462 rkdreisRLDREIERLERELEEERERieELKRKLER 497
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
1436-1805 8.39e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 41.58  E-value: 8.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1436 QQEATIAELELEKQKLQELTRNLRERVTALVRQKDAPSQGQKEEELKAMMQDLqITcgemqrKVELLRYesekLQEENSI 1515
Cdd:TIGR01612 1126 KIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKAISNDDPEEIEKKIENI-VT------KIDKKKN----IYDEIKK 1194
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1516 LRNEITTLnEEDSISNLKLEELNGSQEELWQKI--ETIEQEKASIQTMVEKLKKQVSDL-KIKNQQLDSENiELSQKNSQ 1592
Cdd:TIGR01612 1195 LLNEIAEI-EKDKTSLEEVKGINLSYGKNLGKLflEKIDEEKKKSEHMIKAMEAYIEDLdEIKEKSPEIEN-EMGIEMDI 1272
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1593 NKeELKTLN-------------QRLAEMLCQ-REEPGACTSEKWEQENAS-LKEELDHYKVQTSTLVSSLEAELSEVKLQ 1657
Cdd:TIGR01612 1273 KA-EMETFNishdddkdhhiisKKHDENISDiREKSLKIIEDFSEESDINdIKKELQKNLLDAQKHNSDINLYLNEIANI 1351
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1658 THVMEQENllLKDELERLKQLHRcpDLSDFQQKMSSILSYNEKLLKE-KEVLSeeLKSCADKLaESSLLEHRIATMKQEQ 1736
Cdd:TIGR01612 1352 YNILKLNK--IKKIIDEVKEYTK--EIEENNKNIKDELDKSEKLIKKiKDDIN--LEECKSKI-ESTLDDKDIDECIKKI 1424
                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 554506543  1737 TAWEEQ--SESLKSQLAVSQAKVQNlEDVLQNV-NLQMAEIESDLQVTRQEKEALKQEVMSLHrQLQNAIDK 1805
Cdd:TIGR01612 1425 KELKNHilSEESNIDTYFKNADENN-ENVLLLFkNIEMADNKSQHILKIKKDNATNDHDFNIN-ELKEHIDK 1494
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
359-975 9.07e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.21  E-value: 9.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   359 QAALASFKAEIRHLLERVDQVVREKEKLRSDLDK-AEKLKSL-------MASEVDDHHAAIER------RNEYNLRKLDE 424
Cdd:TIGR02169  243 ERQLASLEEELEKLTEEISELEKRLEEIEQLLEElNKKIKDLgeeeqlrVKEKIGELEAEIASlersiaEKERELEDAEE 322
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   425 E---YKERIAALKNELRQEREQmLQQVGKQRVELEQEIQKAKTEENYIRDRLALSLKENNRLETELLENAEKLAEYESLT 501
Cdd:TIGR02169  323 RlakLEAEIDKLLAEIEELERE-IEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI 401
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   502 QKLQRSLENVLAEKFG------------------------DLDPSSAEFFLQE---ERLAQMRNEYEQQ-------CRLL 547
Cdd:TIGR02169  402 NELKRELDRLQEELQRlseeladlnaaiagieakineleeEKEDKALEIKKQEwklEQLAADLSKYEQElydlkeeYDRV 481
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   548 QDQVDELQSELEEYQAQGRVLRLPLKNS------LSEELDGHSGGIEPDQGPGSEECNPL---------NMSIEAELV-- 610
Cdd:TIGR02169  482 EKELSKLQRELAEAEAQARASEERVRGGraveevLKASIQGVHGTVAQLGSVGERYATAIevaagnrlnNVVVEDDAVak 561
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   611 --IEQMKE---------------QHHRDLCHLRL-----------ELEDKVRHYEKQ-LDDTRVASEQEQAAMkqkyeqg 661
Cdd:TIGR02169  562 eaIELLKRrkagratflplnkmrDERRDLSILSEdgvigfavdlvEFDPKYEPAFKYvFGDTLVVEDIEAARR------- 634
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   662 vHTLEKRVSELRSEIADLEGQAAVLREAHHKASCRHEEEKRQLQMafdeekaqLQEELrQEHERELqARLQQAAESFRQE 741
Cdd:TIGR02169  635 -LMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQR--------LRERL-EGLKREL-SSLQSELRRIENR 703
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   742 REGLAQAAWTEEKVRGLEQSYQEQLLSLEEKHALEKEELREELsehhrRELQEGREEMETECNRRVSQIEAQcQADCEKV 821
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL-----SSLEQEIENVKSELKELEARIEEL-EEDLHKL 777
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   822 TEHCEQTLQSLEVRHRQELRDLLDQHLEERSQWEFEKDELTQEcTDAQEQLKEALQRERATAAAMKQEQEILERTYKDRL 901
Cdd:TIGR02169  778 EEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQK-LNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEI 856
                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 554506543   902 NILSTERKQLLQDLKDLQNAS---ESQHGLLSGQILELKrSQERELRD-QGQALCQTGVSEQLASQQLERLRVEHEQE 975
Cdd:TIGR02169  857 ENLNGKKEELEEELEELEAALrdlESRLGDLKKERDELE-AQLRELERkIEELEAQIEKKRKRLSELKAKLEALEEEL 933
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
782-1604 9.31e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 41.11  E-value: 9.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   782 EELSEHHRRELQEGREEMETECNRRVSQIEAQCQADCEKVTEHCEQTLQSLEVRHRQELRDLLDQHLEERSQWEFEKDEL 861
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   862 TQECTDAQEQLKEALQRERATAAAMKQEQEILERTYKDRLNILSTER---KQLLQDLKDLQNASESQHGLLSGQILELK- 937
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELlklERRKVDDEEKLKESEKEKKKAEKELKKEKe 335
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543   938 ----RSQERELRDQGQALCQTGVSEQLASQQ-LERLRVEHEQERREMTGKLAALESAHRASLERADQEKAEMSTEICRLQ 1012
Cdd:pfam02463  336 eieeLEKELKELEIKREAEEEEEEELEKLQEkLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELAR 415
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1013 NTVKDMQQAASLLMLQGGCQATAGEEAEGDGAMSLLQQGEQLLEENGDVLISLQRAHEHAVKENAKMATEISRLQQRLKK 1092
Cdd:pfam02463  416 QLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKL 495
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1093 LEPGSVISSCLEEGTSEISGSSREQVEPIM-------KQGPATKHFLSDLGDHEARDLASTGTSSVQRQECKTEASEASL 1165
Cdd:pfam02463  496 EERSQKESKARSGLKVLLALIKDGVGGRIIsahgrlgDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPL 575
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1166 DCFSELENSEDTRTESWDLKSQISQL-----REQLTVLRADCDRASERKQDLLFDISVLKK----KLKMLERLPEASSRY 1236
Cdd:pfam02463  576 GARKLRLLIPKLKLPLKSIAVLEIDPilnlaQLDKATLEADEDDKRAKVVEGILKDTELTKlkesAKAKESGLRKGVSLE 655
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1237 KVLYEDAARENSCLQEELRLVETRYEESLDSNKELTAEVYRLQDEMKKMEEvMETFLSLEKSYDEVKVENEELRALVLRL 1316
Cdd:pfam02463  656 EGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ-REKEELKKLKLEAEELLADRVQEAQDKI 734
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1317 QG-----KMEKVLGRAALQGDSYALWEAPSENLEVASDEKMLELRQTPKECTPKVVSMHHIIEEctQETQCCEQGSTKLL 1391
Cdd:pfam02463  735 NEelkllKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKA--QEEELRALEEELKE 812
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1392 ARIKAHEIAwfhrAIKTHPEKPSAQNRVIPEGSAALLGLQDKHLQQEATIaELELEKQKLQELTRNLRERVTALVRQKDA 1471
Cdd:pfam02463  813 EAELLEEEQ----LLIEQEEKIKEEELEELALELKEEQKLEKLAEEELER-LEEEITKEELLQELLLKEEELEEQKLKDE 887
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554506543  1472 PSQGQKEEELKAMMQDLQITCGEMQRKVEllRYESEKLQEENSILRNEITTLNEEDSISNLKLEELNGSQEELWQKIETI 1551
Cdd:pfam02463  888 LESKEEKEKEEKKELEEESQKLNLLEEKE--NEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRL 965
                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....
gi 554506543  1552 EQEKASIQTMVEKLKKQVSDLKIKNQQLDSENIELSQ-KNSQNKEELKTLNQRL 1604
Cdd:pfam02463  966 LLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEeKKKLIRAIIEETCQRL 1019
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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