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Conserved domains on  [gi|472339081|ref|NP_001264259|]
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peroxisomal targeting signal 1 receptor isoform 2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 334-549 5.70e-19

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 90.82  E-value: 5.70e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 334 MEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAvsfTNESLQRQACETLRDWLRYSPAYAHLVAPGEEGAT 413
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALG---LALLLLAALAEAAAAALLALAAGEAAAAAAALLLL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 414 GAGPSKRILgSLLSDSLFLEVKDLFLAAVRLDPTSidPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGA 493
Cdd:COG3914   78 AALLELAAL-LLQALGRYEEALALYRRALALNPDN--AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGE 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 472339081 494 TLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQ 549
Cdd:COG3914  155 ALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 251-399 2.71e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


:

Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.65  E-value: 2.71e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 251 DFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSASYDKGYQFEEENPLRDHPQPFEEGLHRLeeGDLPNAVLLFEAAVQQD 330
Cdd:COG5010    7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKL--GDFEESLALLEQALQLD 84

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 472339081 331 PKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRYSP 399
Cdd:COG5010   85 PNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 334-549 5.70e-19

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 90.82  E-value: 5.70e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 334 MEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAvsfTNESLQRQACETLRDWLRYSPAYAHLVAPGEEGAT 413
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALG---LALLLLAALAEAAAAALLALAAGEAAAAAAALLLL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 414 GAGPSKRILgSLLSDSLFLEVKDLFLAAVRLDPTSidPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGA 493
Cdd:COG3914   78 AALLELAAL-LLQALGRYEEALALYRRALALNPDN--AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGE 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 472339081 494 TLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQ 549
Cdd:COG3914  155 ALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 311-546 6.42e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 72.04  E-value: 6.42e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081  311 LEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSFtneSLQRQACET 390
Cdd:TIGR02917  33 LQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAY---LLQGKFQQV 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081  391 LRdwlrYSPAYAHLVAPGEEGATGAgpskRILGSLLSDSLfLEVKDLFLAAVRLDPTSidPDVQCGLGVLFNLSGEYDKA 470
Cdd:TIGR02917 110 LD----ELPGKTLLDDEGAAELLAL----RGLAYLGLGQL-ELAQKSYEQALAIDPRS--LYAKLGLAQLALAENRFDEA 178

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 472339081  471 VDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHfLEAL 546
Cdd:TIGR02917 179 RALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKH-ADAL 253
TPR_12 pfam13424
Tetratricopeptide repeat;
487-551 1.52e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 46.23  E-value: 1.52e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 472339081  487 MWNKLGATLANGNQSEEAVAAYRRALELQ--------PGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRK 551
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 251-399 2.71e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.65  E-value: 2.71e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 251 DFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSASYDKGYQFEEENPLRDHPQPFEEGLHRLeeGDLPNAVLLFEAAVQQD 330
Cdd:COG5010    7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKL--GDFEESLALLEQALQLD 84

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 472339081 331 PKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRYSP 399
Cdd:COG5010   85 PNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 311-540 3.39e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 46.08  E-value: 3.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 311 LEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNR-TALMALA-VSFTNESLQ--RQ 386
Cdd:cd24142   11 LDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGyEKYLYLGqLSGGEEALQyyEK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 387 ACETLRDWLryspayAHLVAPGEEGATGAGPSKRILGS--------LLSDSLFLE-----VKDLFLAAVRLDPTSidPDV 453
Cdd:cd24142   91 GIEILEEEL------QALQAASAEAEEEAEELKRKLSSalcalaeiYMTDLCDEPdaeqrCEELITKALELDPTN--PEA 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 454 QCGLGVLFNLSGEYDKAVDCFTAALSvrpndylMWNKLGATLANGNQSEEAvaayrrALELQPGYiRSRYNLGISCINLG 533
Cdd:cd24142  163 LQTLASLRISQQRPDEAKEALRRSLE-------LWKDLKEEDEEEAEEDEA------EEEDVPSY-EFRISLAKLLIELE 228


                 ....*..
gi 472339081 534 AHREAVE 540
Cdd:cd24142  229 MYEEALE 235
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 451-484 5.80e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.43  E-value: 5.80e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 472339081   451 PDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPND 484
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
PRY smart00589
associated with SPRY domains;
270-305 5.44e-03

associated with SPRY domains;


Pssm-ID: 128857  Cd Length: 52  Bit Score: 35.24  E-value: 5.44e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 472339081   270 AHPWLSDYDDLTSASYDKGYQfeeenPLRDHPQPFE 305
Cdd:smart00589  11 AHPYLLLSEDRRSVRYGDLKQ-----SLPDNPERFD 41
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 334-549 5.70e-19

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 90.82  E-value: 5.70e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 334 MEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAvsfTNESLQRQACETLRDWLRYSPAYAHLVAPGEEGAT 413
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALG---LALLLLAALAEAAAAALLALAAGEAAAAAAALLLL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 414 GAGPSKRILgSLLSDSLFLEVKDLFLAAVRLDPTSidPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGA 493
Cdd:COG3914   78 AALLELAAL-LLQALGRYEEALALYRRALALNPDN--AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGE 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 472339081 494 TLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQ 549
Cdd:COG3914  155 ALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 304-549 5.01e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 84.40  E-value: 5.01e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 304 FEEGLHRLEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSFTNESL 383
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 384 QRQACETLRDWLRYSPAYAHLVApgeegatgagpskRILGSLLSDSLFLEVKDLFLAAVRLDPTsiDPDVQCGLGVLFNL 463
Cdd:COG2956   92 LDRAEELLEKLLELDPDDAEALR-------------LLAEIYEQEGDWEKAIEVLERLLKLGPE--NAHAYCELAELYLE 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 464 SGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFL 543
Cdd:COG2956  157 QGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLR 236


                 ....*.
gi 472339081 544 EALNMQ 549
Cdd:COG2956  237 KALELD 242
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
436-549 1.55e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 82.36  E-value: 1.55e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 436 DLFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQ 515
Cdd:COG0457   29 EDYEKALELDPD--DAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELD 106

                         90       100       110
                 ....*....|....*....|....*....|....
gi 472339081 516 PGYIRSRYNLGISCINLGAHREAVEHFLEALNMQ 549
Cdd:COG0457  107 PDDAEALYNLGLALLELGRYDEAIEAYERALELD 140
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
327-547 1.65e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 82.36  E-value: 1.65e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 327 VQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSFTNESLQRQACEtlrdwlryspayahlva 406
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALA----------------- 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 407 pgeegatgagpskrilgsllsdslflevkdLFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYL 486
Cdd:COG0457   64 ------------------------------DYEQALELDPD--DAEALNNLGLALQALGRYEEALEDYDKALELDPDDAE 111

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 472339081 487 MWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALN 547
Cdd:COG0457  112 ALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEA 172
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
442-549 1.12e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 76.97  E-value: 1.12e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 442 VRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPGYIRS 521
Cdd:COG0457    1 LELDPD--DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEA 78

                         90       100
                 ....*....|....*....|....*...
gi 472339081 522 RYNLGISCINLGAHREAVEHFLEALNMQ 549
Cdd:COG0457   79 LNNLGLALQALGRYEEALEDYDKALELD 106
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 433-546 5.73e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 69.07  E-value: 5.73e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 433 EVKDLFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRAL 512
Cdd:COG4783   22 EAEALLEKALELDPD--NPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKAL 99

                         90       100       110
                 ....*....|....*....|....*....|....
gi 472339081 513 ELQPGYIRSRYNLGISCINLGAHREAVEHFLEAL 546
Cdd:COG4783  100 KLDPEHPEAYLRLARAYRALGRPDEAIAALEKAL 133
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 314-525 6.52e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 74.64  E-value: 6.52e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 314 GDLPNAVLLFEAAVQQDPKHMEAWQYLG----TTQAENEQELLAISALRRCLELKPDNRTALMALAVSFTNESLQRQ--- 386
Cdd:COG3914   15 AALLAAAAAAELALAAELEAAALAAALGlallLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALgry 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 387 --ACETLRDWLRYSPAYAhlvapgeegatgagPSKRILGSLLSDS-LFLEVKDLFLAAVRLDPTsiDPDVQCGLGVLFNL 463
Cdd:COG3914   95 eeALALYRRALALNPDNA--------------EALFNLGNLLLALgRLEEALAALRRALALNPD--FAEAYLNLGEALRR 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 472339081 464 SGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 525
Cdd:COG3914  159 LGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 440-548 1.39e-13

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 67.72  E-value: 1.39e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 440 AAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPGYI 519
Cdd:COG4235    8 QALAANPN--DAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                         90       100
                 ....*....|....*....|....*....
gi 472339081 520 RSRYNLGISCINLGAHREAVEHFLEALNM 548
Cdd:COG4235   86 EALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
457-546 3.68e-13

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 69.17  E-value: 3.68e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 457 LGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHR 536
Cdd:COG4785   79 RGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYE 158

                         90
                 ....*....|
gi 472339081 537 EAVEHFLEAL 546
Cdd:COG4785  159 LAIADLEKAL 168
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 311-546 6.42e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 72.04  E-value: 6.42e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081  311 LEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSFtneSLQRQACET 390
Cdd:TIGR02917  33 LQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAY---LLQGKFQQV 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081  391 LRdwlrYSPAYAHLVAPGEEGATGAgpskRILGSLLSDSLfLEVKDLFLAAVRLDPTSidPDVQCGLGVLFNLSGEYDKA 470
Cdd:TIGR02917 110 LD----ELPGKTLLDDEGAAELLAL----RGLAYLGLGQL-ELAQKSYEQALAIDPRS--LYAKLGLAQLALAENRFDEA 178

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 472339081  471 VDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHfLEAL 546
Cdd:TIGR02917 179 RALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKH-ADAL 253
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
465-553 8.90e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 58.64  E-value: 8.90e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 465 GEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVaAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLE 544
Cdd:COG3063    6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLER 84


                 ....*....
gi 472339081 545 ALNMQRKSR 553
Cdd:COG3063   85 ALELDPSAL 93
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 457-549 9.23e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.21  E-value: 9.23e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 457 LGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHR 536
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                         90
                 ....*....|...
gi 472339081 537 EAVEHFLEALNMQ 549
Cdd:COG4783   90 EALALLEKALKLD 102
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 298-525 1.46e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 64.33  E-value: 1.46e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081  298 RDHPQP-FEEGLHRLEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAV 376
Cdd:TIGR02917 258 PNSPLAhYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLAS 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081  377 SFTNESLQRQACETLRDWLRYSP---------AYAHLVAPGEEGA-------------TGAGPSKRILGSLLSDSLFLEV 434
Cdd:TIGR02917 338 IQLRLGRVDEAIATLSPALGLDPddpaalsllGEAYLALGDFEKAaeylakateldpeNAAARTQLGISKLSQGDPSEAI 417

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081  435 KDLfLAAVRLDPTSIDPDVQCGLGVLfnLSGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALEL 514
Cdd:TIGR02917 418 ADL-ETAAQLDPELGRADLLLILSYL--RSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSI 494

                         250
                  ....*....|.
gi 472339081  515 QPGYIRSRYNL 525
Cdd:TIGR02917 495 EPDFFPAAANL 505
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 459-547 5.83e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 58.05  E-value: 5.83e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 459 VLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREA 538
Cdd:COG5010   62 NLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA 141


                 ....*....
gi 472339081 539 VEHFLEALN 547
Cdd:COG5010  142 KAALQRALG 150
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 436-552 4.32e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.82  E-value: 4.32e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 436 DLFLAAVRLDPTSIDpdVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQ 515
Cdd:COG2956   29 DLLEEALELDPETVE--AHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELD 106

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 472339081 516 PGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKS 552
Cdd:COG2956  107 PDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN 143
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 311-549 2.12e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.89  E-value: 2.12e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 311 LEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVsftneslqrqacet 390
Cdd:COG2956   87 LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAE-------------- 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 391 lrdwlryspayahlvapgeegatgagpskrilgSLLSDSLFLEVKDLFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKA 470
Cdd:COG2956  153 ---------------------------------LYLEQGDYDEAIEALEKALKLDPD--CARALLLLAELYLEQGDYEEA 197

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 472339081 471 VDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPGyIRSRYNLGISCINLGAHREAVEHFLEALNMQ 549
Cdd:COG2956  198 IAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQLRRH 275
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 307-404 2.57e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.93  E-value: 2.57e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 307 GLHRLEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSFTNESLQRQ 386
Cdd:COG3914  119 GNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEE 198

                         90
                 ....*....|....*...
gi 472339081 387 ACETLRDWLRYSPAYAHL 404
Cdd:COG3914  199 AIAAYRRALELDPDNADA 216
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 319-484 7.43e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.55  E-value: 7.43e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 319 AVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSFTNESLQRQAcetlrdwlrys 398
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEA----------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 399 payahlvapgeegatgagpskrilgsllsdslflevKDLFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAAL 478
Cdd:COG4235   71 ------------------------------------EELLERALALDPD--NPEALYLLGLAAFQQGDYAEAIAAWQKLL 112


                 ....*.
gi 472339081 479 SVRPND 484
Cdd:COG4235  113 ALLPAD 118
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 298-516 9.44e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.09  E-value: 9.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081  298 RDHPQPFE-EGLHRLEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAV 376
Cdd:TIGR02917 598 PDSPEAWLmLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQ 677

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081  377 SFTNESLQRQACETLRDWLRYSPAYAhlvapgeegatgagpskriLGSLLSDSLFLEVKDL------FLAAVRLDPTSid 450
Cdd:TIGR02917 678 LLLAAKRTESAKKIAKSLQKQHPKAA-------------------LGFELEGDLYLRQKDYpaaiqaYRKALKRAPSS-- 736

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 472339081  451 pDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQP 516
Cdd:TIGR02917 737 -QNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAP 801
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
438-558 1.07e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 53.00  E-value: 1.07e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 438 FLAAVRLDPTSidPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPG 517
Cdd:COG4785   96 FDQALELDPDL--AEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPN 173

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 472339081 518 YIRSRYNLGISCINLGAHrEAVEHFLEALNMQRKSRGPRGE 558
Cdd:COG4785  174 DPERALWLYLAERKLDPE-KALALLLEDWATAYLLQGDTEE 213
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 370-516 1.30e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 51.50  E-value: 1.30e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 370 ALMALAVSFTNESLQRQACETLRDWLRYSPAYAHLVAPGEEGATGAGPSKRILGSLLSDSLFLEVKDLFLAAVRLDPTsi 449
Cdd:COG5010    9 RLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPN-- 86

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 472339081 450 DPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQP 516
Cdd:COG5010   87 NPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 469-546 1.62e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.39  E-value: 1.62e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 472339081 469 KAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEAL 546
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERAL 78
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 457-552 2.56e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 52.42  E-value: 2.56e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 457 LGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHR 536
Cdd:COG2956   14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLD 93

                         90
                 ....*....|....*.
gi 472339081 537 EAVEHFLEALNMQRKS 552
Cdd:COG2956   94 RAEELLEKLLELDPDD 109
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 298-402 6.13e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.03  E-value: 6.13e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 298 RDHPQPFEEGLHRLEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVS 377
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                         90       100
                 ....*....|....*....|....*
gi 472339081 378 FTNESLQRQACETLRDWLRYSPAYA 402
Cdd:COG4783   82 LLKAGDYDEALALLEKALKLDPEHP 106
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 437-518 8.10e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 48.65  E-value: 8.10e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 437 LFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQP 516
Cdd:COG4783   60 LLHEALELDPD--EPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137


                 ..
gi 472339081 517 GY 518
Cdd:COG4783  138 DD 139
TPR_12 pfam13424
Tetratricopeptide repeat;
487-551 1.52e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 46.23  E-value: 1.52e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 472339081  487 MWNKLGATLANGNQSEEAVAAYRRALELQ--------PGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRK 551
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 307-404 1.78e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 51.15  E-value: 1.78e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 307 GLHRLEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAvsftneSLQRQ 386
Cdd:COG3914  153 GEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLL------FALRQ 226

                         90
                 ....*....|....*...
gi 472339081 387 ACetlrDWLRYSPAYAHL 404
Cdd:COG3914  227 AC----DWEVYDRFEELL 240
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 307-402 2.28e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.31  E-value: 2.28e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 307 GLHRLEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSFTNESLQRQ 386
Cdd:COG4235   24 GRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAE 103

                         90
                 ....*....|....*.
gi 472339081 387 ACETLRDWLRYSPAYA 402
Cdd:COG4235  104 AIAAWQKLLALLPADA 119
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 251-399 2.71e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.65  E-value: 2.71e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 251 DFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSASYDKGYQFEEENPLRDHPQPFEEGLHRLeeGDLPNAVLLFEAAVQQD 330
Cdd:COG5010    7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKL--GDFEESLALLEQALQLD 84

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 472339081 331 PKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRYSP 399
Cdd:COG5010   85 PNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
435-516 2.88e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 45.93  E-value: 2.88e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 435 KDLFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDcFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALEL 514
Cdd:COG3063   12 EEYYEKALELDPD--NADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALEL 88


                 ..
gi 472339081 515 QP 516
Cdd:COG3063   89 DP 90
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 311-401 6.21e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.95  E-value: 6.21e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 311 LEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSFTNESLQRQACET 390
Cdd:COG4783   49 LQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAA 128

                         90
                 ....*....|.
gi 472339081 391 LRDWLRYSPAY 401
Cdd:COG4783  129 LEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 290-406 6.82e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.19  E-value: 6.82e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 290 QFEEENPLRDHPQpFEEGLHRLEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRT 369
Cdd:COG2956  135 RLLKLGPENAHAY-CELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLP 213

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 472339081 370 ALMALAVSFTNESLQRQACETLRDWLRYSPAYAHLVA 406
Cdd:COG2956  214 ALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLA 250
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 441-516 1.21e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.00  E-value: 1.21e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 472339081 441 AVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQP 516
Cdd:COG4235   43 ALRLDPD--NADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLP 116
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 311-551 1.40e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 1.40e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081  311 LEEGDLPNAVLLFEAAVQQDPKHMEAWQ-----------------YLGTTQAENEQEL-----------------LAISA 356
Cdd:TIGR02917 510 IQEGNPDDAIQRFEKVLTIDPKNLRAILalaglylrtgneeeavaWLEKAAELNPQEIepalalaqyylgkgqlkKALAI 589

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081  357 LRRCLELKPDNRTALMALAVSFTNESLQRQACETLRDWLRYSP---------AYAHLVAPGEEGATGAgpSKRIL----- 422
Cdd:TIGR02917 590 LNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPdsalallllADAYAVMKNYAKAITS--LKRALelkpd 667

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081  423 ---GSLLSDSLFLEVKDlFLAAVRLDPT-----SIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLMWNKLGAT 494
Cdd:TIGR02917 668 nteAQIGLAQLLLAAKR-TESAKKIAKSlqkqhPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKLHRAL 746

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 472339081  495 LANGNQSeEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRK 551
Cdd:TIGR02917 747 LASGNTA-EAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPD 802
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
304-378 1.41e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 46.45  E-value: 1.41e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 472339081 304 FEEGLHRLEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALMALAVSF 378
Cdd:COG4785   77 YERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIAL 151
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
311-400 1.58e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.62  E-value: 1.58e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 311 LEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAIsALRRCLELKPDNRTALMALAVSFTNESLQRQACET 390
Cdd:COG3063    3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAY 81

                         90
                 ....*....|
gi 472339081 391 LRDWLRYSPA 400
Cdd:COG3063   82 LERALELDPS 91
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 464-547 1.72e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.21  E-value: 1.72e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 464 SGEYDKAVDCFTAALSVRPNDYLMWN---KLGATLANGNQSEEAVAAYRRALELQPGYIR---SRYNLGISCINLGAHRE 537
Cdd:COG1729    6 AGDYDEAIAAFKAFLKRYPNSPLAPDalyWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDYDK 85

                         90
                 ....*....|
gi 472339081 538 AVEHFLEALN 547
Cdd:COG1729   86 ARATLEELIK 95
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 314-372 2.09e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 44.23  E-value: 2.09e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 472339081 314 GDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNRTALM 372
Cdd:COG4235   65 GDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARL 123
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 311-540 3.39e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 46.08  E-value: 3.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 311 LEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNR-TALMALA-VSFTNESLQ--RQ 386
Cdd:cd24142   11 LDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGyEKYLYLGqLSGGEEALQyyEK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 387 ACETLRDWLryspayAHLVAPGEEGATGAGPSKRILGS--------LLSDSLFLE-----VKDLFLAAVRLDPTSidPDV 453
Cdd:cd24142   91 GIEILEEEL------QALQAASAEAEEEAEELKRKLSSalcalaeiYMTDLCDEPdaeqrCEELITKALELDPTN--PEA 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 454 QCGLGVLFNLSGEYDKAVDCFTAALSvrpndylMWNKLGATLANGNQSEEAvaayrrALELQPGYiRSRYNLGISCINLG 533
Cdd:cd24142  163 LQTLASLRISQQRPDEAKEALRRSLE-------LWKDLKEEDEEEAEEDEA------EEEDVPSY-EFRISLAKLLIELE 228


                 ....*..
gi 472339081 534 AHREAVE 540
Cdd:cd24142  229 MYEEALE 235
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 476-582 3.61e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.18  E-value: 3.61e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 476 AALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKsrgp 555
Cdd:COG5010   45 AGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---- 120

                         90       100
                 ....*....|....*....|....*..
gi 472339081 556 rgeggamSENIWSTLRLALSMLGQSDA 582
Cdd:COG5010  121 -------NPNAYSNLAALLLSLGQDDE 140
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 311-517 4.85e-05

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 45.67  E-value: 4.85e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 311 LEEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTT--QAENEQELLAI-SALRRCLELKPDNRTALMALAVSftnESLQRQA 387
Cdd:COG3071   96 LDQGQAEQALATLEALRAGAPRHPQVLRLLLQAyrQLGDWEELLELlPALRKHKALSAEEAQALERRAYL---GLLRQAA 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 388 --CETLRDW-------LRYSPAYA-----HLVAPGE--------EGATGAGPSKRiLGSLLSDSLFLEVKDLFL---AAV 442
Cdd:COG3071  173 rdAEALKALwkalpraERRDPELAaayarALIALGDhdeaerllREALKRQWDPR-LVRLYGRLQGGDPAKQLKraeKWL 251

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 472339081 443 RLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPN--DYLMwnkLGATLANGNQSEEAVAAYRRALELQPG 517
Cdd:COG3071  252 KKHPN--DPDLLLALGRLCLRNQLWGKAREYLEAALALRPSaeAYAE---LARLLEQLGDPEEAAEHYRKALALALG 323
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
481-546 4.92e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 44.91  E-value: 4.92e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 472339081 481 RPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEAL 546
Cdd:COG4785   69 LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRAL 134
TPR_1 pfam00515
Tetratricopeptide repeat;
451-484 3.21e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.17  E-value: 3.21e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 472339081  451 PDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPND 484
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 451-484 5.80e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.43  E-value: 5.80e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 472339081   451 PDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPND 484
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
LcrH_SycD TIGR02552
type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in ...
 464-572 6.98e-04

type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in type III secretion operons. LcrH, from Yersinia is believed to have a regulatory function in the low-calcium response of the secretion system. The same protein is also known as SycD (SYC = Specific Yop Chaperone) for its chaperone role. In Pseudomonas, where the homolog is known as PcrH, the chaperone role has been demonstrated and the regulatory role appears to be absent. ScyD/LcrH contains three central tetratricopeptide-like repeats that are predicted to fold into an all-alpha-helical array.


Pssm-ID: 274197 [Multi-domain]  Cd Length: 135  Bit Score: 39.97  E-value: 6.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081  464 SGEYDKAVDCFTAALSVRPNDYLMWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFL 543
Cdd:TIGR02552  30 QGRYDEALKLFQLLAAYDPYNSRYWLGLAACCQMLKEYEEAIDAYALAAALDPDDPRPYFHAAECLLALGEPESALKALD 109

                          90       100
                  ....*....|....*....|....*....
gi 472339081  544 EALNMQRKSRgprgEGGAMSENIWSTLRL 572
Cdd:TIGR02552 110 LAIEICGENP----EYSELKERAEAMLES 134
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 311-399 1.87e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 38.43  E-value: 1.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 472339081 311 LEEGDLPNAVLLFEAAVQQDPKHM---EAWQYLGTTQAENEQELLAISALRRCLELKPDNRT---ALMALAVSFTNESLQ 384
Cdd:COG1729    4 LKAGDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDY 83

                         90
                 ....*....|....*
gi 472339081 385 RQACETLRDWLRYSP 399
Cdd:COG1729   84 DKARATLEELIKKYP 98
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 488-553 3.38e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 38.25  E-value: 3.38e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 472339081 488 WNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSR 553
Cdd:COG4783    7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEP 72
TPR_11 pfam13414
TPR repeat;
499-526 3.78e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 35.53  E-value: 3.78e-03
                          10        20
                  ....*....|....*....|....*...
gi 472339081  499 NQSEEAVAAYRRALELQPGYIRSRYNLG 526
Cdd:pfam13414   8 GKYEEAIEAYKKALKLDPDNPEAYYNLG 35
TPR_1 pfam00515
Tetratricopeptide repeat;
488-518 4.14e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.09  E-value: 4.14e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 472339081  488 WNKLGATLANGNQSEEAVAAYRRALELQPGY 518
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
PRY smart00589
associated with SPRY domains;
270-305 5.44e-03

associated with SPRY domains;


Pssm-ID: 128857  Cd Length: 52  Bit Score: 35.24  E-value: 5.44e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 472339081   270 AHPWLSDYDDLTSASYDKGYQfeeenPLRDHPQPFE 305
Cdd:smart00589  11 AHPYLLLSEDRRSVRYGDLKQ-----SLPDNPERFD 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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