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Conserved domains on  [gi|394025701|ref|NP_001257364|]
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coiled-coil domain-containing protein 30 isoform b [Mus musculus]

Protein Classification

coiled-coil domain-containing protein 30( domain architecture ID 13382606)

coiled-coil domain-containing protein 30 (CCDC30) is a DUF4686 domain-containing protein that may be a new cytoskeletal element functionally associated with the filament motor system of the cytoskeleton

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4686 pfam15742
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ...
 165-542 5.16e-143

Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.


:

Pssm-ID: 464838 [Multi-domain]  Cd Length: 384  Bit Score: 421.39  E-value: 5.16e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  165 LTSGEKTSCQHQGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSS 244
Cdd:pfam15742   1 VSSGEKLKYQQQEEVQQLRQNLQRLQILCTSAEKELRYERGKNLDLKQHNSLLQEENIKIKAELKQAQQKLLDSTKMCSS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  245 LTAEWKHCQQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSDVCILRKKQLEEEI 324
Cdd:pfam15742  81 LTAEWKHCQQKIRELELEVLKQAQSIKSQNSLQEKLAQEKSRVADAEEKILELQQKLEHAHKVCLTDTCILEKKQLEERI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  325 KEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNS------QQQEALRKQLERERRKCEEYVKSN 398
Cdd:pfam15742 161 KEASENEAKLKQQYQEEQQKRKLLDQNVNELQQQVRSLQDKEAQLEMTNSqqqlriQQQEAQLKQLENEKRKSDEHLKSN 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  399 QELSEKLSNLQQEKEALWQEHGRFLEQLGDHVRNYKDKHHCHKAKLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIEM 478
Cdd:pfam15742 241 QELSEKLSSLQQEKEALQEELQQVLKQLDVHVRKYNEKHHHHKAKLRRAKDRLVHEVEQRDERIKQLENEIGILQQQSEK 320

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 394025701  479 EKVFQGQIMAQNDILLLEKRKLLEQVTDQEELICSSKCTISAFQSKASLLDKENQQLQENCLRL 542
Cdd:pfam15742 321 EKAFQKQVTAQNEILLLEKRKLLEQLTEQEELIKNNKRTISSVQNRVNFLDEENKQLQENTLRL 384
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 24-292 2.90e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.08  E-value: 2.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  24 ERRTLAEALGLVDSTLESRRDPNSSLQKEFPQHQDEDQSRAAAPQDcLLRDVECIAQKLEASLEEIHRgareprEEREQR 103
Cdd:COG1196  254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR-LEQDIARLEERRRELEERLEE------LEEELA 326

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 104 TLGDALENARLEIEKLKDNLMKLKESGTTDLQRAREHNQRLDEEILALRNRVRSLDSEKKyltsgektscqhqgELRELR 183
Cdd:COG1196  327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE--------------ELLEAL 392

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 184 QNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELELEG 263
Cdd:COG1196  393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                        250       260
                 ....*....|....*....|....*....
gi 394025701 264 LRQTQSLKSQQGLQEKLAREKSKAAEAQE 292
Cdd:COG1196  473 ALLEAALAELLEELAEAAARLLLLLEAEA 501
 
Name Accession Description Interval E-value
DUF4686 pfam15742
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ...
 165-542 5.16e-143

Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.


Pssm-ID: 464838 [Multi-domain]  Cd Length: 384  Bit Score: 421.39  E-value: 5.16e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  165 LTSGEKTSCQHQGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSS 244
Cdd:pfam15742   1 VSSGEKLKYQQQEEVQQLRQNLQRLQILCTSAEKELRYERGKNLDLKQHNSLLQEENIKIKAELKQAQQKLLDSTKMCSS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  245 LTAEWKHCQQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSDVCILRKKQLEEEI 324
Cdd:pfam15742  81 LTAEWKHCQQKIRELELEVLKQAQSIKSQNSLQEKLAQEKSRVADAEEKILELQQKLEHAHKVCLTDTCILEKKQLEERI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  325 KEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNS------QQQEALRKQLERERRKCEEYVKSN 398
Cdd:pfam15742 161 KEASENEAKLKQQYQEEQQKRKLLDQNVNELQQQVRSLQDKEAQLEMTNSqqqlriQQQEAQLKQLENEKRKSDEHLKSN 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  399 QELSEKLSNLQQEKEALWQEHGRFLEQLGDHVRNYKDKHHCHKAKLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIEM 478
Cdd:pfam15742 241 QELSEKLSSLQQEKEALQEELQQVLKQLDVHVRKYNEKHHHHKAKLRRAKDRLVHEVEQRDERIKQLENEIGILQQQSEK 320

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 394025701  479 EKVFQGQIMAQNDILLLEKRKLLEQVTDQEELICSSKCTISAFQSKASLLDKENQQLQENCLRL 542
Cdd:pfam15742 321 EKAFQKQVTAQNEILLLEKRKLLEQLTEQEELIKNNKRTISSVQNRVNFLDEENKQLQENTLRL 384
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 167-473 7.28e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.47  E-value: 7.28e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   167 SGEKTSCQHQGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLT 246
Cdd:TIGR02169  664 GGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE 743

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   247 AEWKHCQQKVKELELEglrqtqslksQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSDvcilRKKQLEEEIKE 326
Cdd:TIGR02169  744 EDLSSLEQEIENVKSE----------LKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQA----ELSKLEEEVSR 809

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   327 AKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDkeeqQEAVNSQQQEALRKQLERERRKCEEYVKSNQELSEKLS 406
Cdd:TIGR02169  810 IEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKE----QIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG 885

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   407 NLQQEKealwqehgrflEQLGDHVRNYKDKHHCHKAKLQKVKDR---LTHELEIRNKRIKELEDETGKLQ 473
Cdd:TIGR02169  886 DLKKER-----------DELEAQLRELERKIEELEAQIEKKRKRlseLKAKLEALEEELSEIEDPKGEDE 944
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 108-390 9.30e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 9.30e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 108 ALENARLEIEKLKDNLmklkESGTTDLQRAREHNQRLDEEILALRNRVRSLDSEkkyltsgektscqhqgeLRELRQNLR 187
Cdd:COG1196  233 KLRELEAELEELEAEL----EELEAELEELEAELAELEAELEELRLELEELELE-----------------LEEAQAEEY 291

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 188 RLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELELEGLRQT 267
Cdd:COG1196  292 ELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE 371

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 268 QSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSDVCILRKKQLEEEIKEAKSIEARLQQQCQEEQQRRiL 347
Cdd:COG1196  372 AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE-E 450

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 394025701 348 LDQDINELQTQVRALQDKEEQQEAVNSQQQEALRKQLERERRK 390
Cdd:COG1196  451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
115-415 9.13e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 9.13e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 115 EIEKLKDNLMKLKESGTTDLQRAREHNQRLDEEILALRNRVRSLDSEKKYLTSGEKTSCQHQGELRELRQNLRRLQILCN 194
Cdd:PRK03918 190 NIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIE 269

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 195 SAEKELRYERGRSLDLKQHNSlLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELELEGLRQTQSLKSQQ 274
Cdd:PRK03918 270 ELKKEIEELEEKVKELKELKE-KAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLK 348

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 275 GLQEKLAREKsKAAEAQEKILDLQQKLDHGRqvclSDVCILRKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQDINE 354
Cdd:PRK03918 349 ELEKRLEELE-ERHELYEEAKAKKEELERLK----KRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKE 423

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 394025701 355 LQTQVRALQDKEEQQEAVNSQQQEALRKQLERE-RRKCEEYVKSNQELSEKLSNLQQEKEAL 415
Cdd:PRK03918 424 LKKAIEELKKAKGKCPVCGRELTEEHRKELLEEyTAELKRIEKELKEIEEKERKLRKELREL 485
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 24-292 2.90e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.08  E-value: 2.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  24 ERRTLAEALGLVDSTLESRRDPNSSLQKEFPQHQDEDQSRAAAPQDcLLRDVECIAQKLEASLEEIHRgareprEEREQR 103
Cdd:COG1196  254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR-LEQDIARLEERRRELEERLEE------LEEELA 326

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 104 TLGDALENARLEIEKLKDNLMKLKESGTTDLQRAREHNQRLDEEILALRNRVRSLDSEKKyltsgektscqhqgELRELR 183
Cdd:COG1196  327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE--------------ELLEAL 392

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 184 QNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELELEG 263
Cdd:COG1196  393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                        250       260
                 ....*....|....*....|....*....
gi 394025701 264 LRQTQSLKSQQGLQEKLAREKSKAAEAQE 292
Cdd:COG1196  473 ALLEAALAELLEELAEAAARLLLLLEAEA 501
 
Name Accession Description Interval E-value
DUF4686 pfam15742
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ...
 165-542 5.16e-143

Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.


Pssm-ID: 464838 [Multi-domain]  Cd Length: 384  Bit Score: 421.39  E-value: 5.16e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  165 LTSGEKTSCQHQGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSS 244
Cdd:pfam15742   1 VSSGEKLKYQQQEEVQQLRQNLQRLQILCTSAEKELRYERGKNLDLKQHNSLLQEENIKIKAELKQAQQKLLDSTKMCSS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  245 LTAEWKHCQQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSDVCILRKKQLEEEI 324
Cdd:pfam15742  81 LTAEWKHCQQKIRELELEVLKQAQSIKSQNSLQEKLAQEKSRVADAEEKILELQQKLEHAHKVCLTDTCILEKKQLEERI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  325 KEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNS------QQQEALRKQLERERRKCEEYVKSN 398
Cdd:pfam15742 161 KEASENEAKLKQQYQEEQQKRKLLDQNVNELQQQVRSLQDKEAQLEMTNSqqqlriQQQEAQLKQLENEKRKSDEHLKSN 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  399 QELSEKLSNLQQEKEALWQEHGRFLEQLGDHVRNYKDKHHCHKAKLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIEM 478
Cdd:pfam15742 241 QELSEKLSSLQQEKEALQEELQQVLKQLDVHVRKYNEKHHHHKAKLRRAKDRLVHEVEQRDERIKQLENEIGILQQQSEK 320

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 394025701  479 EKVFQGQIMAQNDILLLEKRKLLEQVTDQEELICSSKCTISAFQSKASLLDKENQQLQENCLRL 542
Cdd:pfam15742 321 EKAFQKQVTAQNEILLLEKRKLLEQLTEQEELIKNNKRTISSVQNRVNFLDEENKQLQENTLRL 384
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 167-473 7.28e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.47  E-value: 7.28e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   167 SGEKTSCQHQGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLT 246
Cdd:TIGR02169  664 GGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE 743

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   247 AEWKHCQQKVKELELEglrqtqslksQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSDvcilRKKQLEEEIKE 326
Cdd:TIGR02169  744 EDLSSLEQEIENVKSE----------LKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQA----ELSKLEEEVSR 809

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   327 AKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDkeeqQEAVNSQQQEALRKQLERERRKCEEYVKSNQELSEKLS 406
Cdd:TIGR02169  810 IEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKE----QIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG 885

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   407 NLQQEKealwqehgrflEQLGDHVRNYKDKHHCHKAKLQKVKDR---LTHELEIRNKRIKELEDETGKLQ 473
Cdd:TIGR02169  886 DLKKER-----------DELEAQLRELERKIEELEAQIEKKRKRlseLKAKLEALEEELSEIEDPKGEDE 944
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 108-390 9.30e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 9.30e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 108 ALENARLEIEKLKDNLmklkESGTTDLQRAREHNQRLDEEILALRNRVRSLDSEkkyltsgektscqhqgeLRELRQNLR 187
Cdd:COG1196  233 KLRELEAELEELEAEL----EELEAELEELEAELAELEAELEELRLELEELELE-----------------LEEAQAEEY 291

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 188 RLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELELEGLRQT 267
Cdd:COG1196  292 ELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE 371

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 268 QSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSDVCILRKKQLEEEIKEAKSIEARLQQQCQEEQQRRiL 347
Cdd:COG1196  372 AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE-E 450

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 394025701 348 LDQDINELQTQVRALQDKEEQQEAVNSQQQEALRKQLERERRK 390
Cdd:COG1196  451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 178-477 2.06e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 2.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 178 ELRELRQNLRRLQILCNS-----------AEKELRYER-GRSLDLKQHNSLLQEENiKIKIELKQAQEKLLDNARLHSSL 245
Cdd:COG1196  180 KLEATEENLERLEDILGElerqleplerqAEKAERYRElKEELKELEAELLLLKLR-ELEAELEELEAELEELEAELEEL 258

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 246 TAEWKHCQQKVKELELEGLRQTQSLKSQQG----LQEKLAREKSKAAEAQEKILDLQQKLDHGRQvclsdvcilRKKQLE 321
Cdd:COG1196  259 EAELAELEAELEELRLELEELELELEEAQAeeyeLLAELARLEQDIARLEERRRELEERLEELEE---------ELAELE 329

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 322 EEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEavnsQQQEALRKQLERERRKCEEYVKSNQEL 401
Cdd:COG1196  330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE----EELEELAEELLEALRAAAELAAQLEEL 405

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 394025701 402 SEKLSNLQQEKEALWQEHGRFLEQLgDHVRNYKDKHHCHKAKLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIE 477
Cdd:COG1196  406 EEAEEALLERLERLEEELEELEEAL-AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 178-477 3.10e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.46  E-value: 3.10e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   178 ELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVK 257
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   258 ELELEglrqtqslksQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQvclsdvcilRKKQLEEEIKEAKSIEARLQQQ 337
Cdd:TIGR02168  758 ELEAE----------IEELEERLEEAEEELAEAEAEIEELEAQIEQLKE---------ELKALREALDELRAELTLLNEE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   338 CQEEQQRRILLDQDINELQTQVRALqdkeEQQEAVNSQQQEALRKQLERERRKCEEyvkSNQELsEKLSNLQQEKEALWQ 417
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLEDL----EEQIEELSEDIESLAAEIEELEELIEE---LESEL-EALLNERASLEEALA 890

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   418 EHGRFLEQLGDHVRNYKDKhhchkaklqkvKDRLTHELEIRNKRIKELEDETGKLQQKIE 477
Cdd:TIGR02168  891 LLRSELEELSEELRELESK-----------RSELRRELEELREKLAQLELRLEGLEVRID 939
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 71-386 1.33e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.94  E-value: 1.33e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  71 LLRDVECIAQKLEASLEEIHRGAREPREEREQRTLGDA-LENARLEIEKLKDnlmklkesgttDLQRAREHNQRLDEEIL 149
Cdd:COG1196  230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAeLEELRLELEELEL-----------ELEEAQAEEYELLAELA 298

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 150 ALRNRVRSLDSEKKYLtsgektscqhQGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELK 229
Cdd:COG1196  299 RLEQDIARLEERRREL----------EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 230 QAQEKLLDNARlhsSLTAEWKHCQQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCL 309
Cdd:COG1196  369 EAEAELAEAEE---ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 394025701 310 SDvcILRKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNSQQQEALRKQLER 386
Cdd:COG1196  446 EA--AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR 520
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 253-511 3.03e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.79  E-value: 3.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 253 QQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVclSDVCILRKKQLEEEIKEAKSIEA 332
Cdd:COG1196  221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLE--LEELELELEEAQAEEYELLAELA 298

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 333 RLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNSQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQEK 412
Cdd:COG1196  299 RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 413 EALWQEHGRFLEQLGDHVRNYKDKHHchkakLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIEMEKVFQGQIMAQNDI 492
Cdd:COG1196  379 EELEELAEELLEALRAAAELAAQLEE-----LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                        250
                 ....*....|....*....
gi 394025701 493 LLLEKRKLLEQVTDQEELI 511
Cdd:COG1196  454 LEEEEEALLELLAELLEEA 472
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 109-426 2.55e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.83  E-value: 2.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   109 LENARLEIEKLKDNLMKLKESGttdlQRAREHNQRLDE-EILALRNRVRSLDSEKKYLTSGEKtscQHQGELRELRQNLR 187
Cdd:TIGR02168  191 LEDILNELERQLKSLERQAEKA----ERYKELKAELRElELALLVLRLEELREELEELQEELK---EAEEELEELTAELQ 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   188 RLQILCNSAEKElRYERGRSLDLKQHNSLlqeeNIKIKIELKQAQEKLLDNARlhssltaewkhcQQKVKELELEGLRQT 267
Cdd:TIGR02168  264 ELEEKLEELRLE-VSELEEEIEELQKELY----ALANEISRLEQQKQILRERL------------ANLERQLEELEAQLE 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   268 QSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQvcLSDVCILRKKQLEEEIKEAKSIEARLQQQCQEEQQRRIL 347
Cdd:TIGR02168  327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEA--ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   348 LDQDINELQTQV-RALQDKEEQQEAVNSQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQEKEALWQEHGRFLEQL 426
Cdd:TIGR02168  405 LEARLERLEDRReRLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL 484
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 278-557 3.80e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.45  E-value: 3.80e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   278 EKLAREKSKAaeaqEKILDLQQKLDHGRQVCLSdvciLRKKQLEEEIKEaksIEARLQQQCQEEQQRRILLDQDINELQT 357
Cdd:TIGR02169  201 ERLRREREKA----ERYQALLKEKREYEGYELL----KEKEALERQKEA---IERQLASLEEELEKLTEEISELEKRLEE 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   358 QVRALQDKEEQQEAVNSQQQEALRKQL-------ERERRKCEEYVKSNQELSEKLSNLQQEKEALWQEHGRFLEQLGDhV 430
Cdd:TIGR02169  270 IEQLLEELNKKIKDLGEEEQLRVKEKIgeleaeiASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEE-E 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   431 RNYKDKHHCHKAKLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIEMEKVFQGQIMAQNDILLLEKRKLLEQVTDQEEL 510
Cdd:TIGR02169  349 RKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAA 428

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 394025701   511 ICSSKCTISAFQSKASLLDKENQQLQENCLRLMQQIGLLEQIIRSIQ 557
Cdd:TIGR02169  429 IAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLK 475
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 225-477 1.02e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.90  E-value: 1.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   225 KIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELE--LEGLRQTQSLKSQQ--GLQEKLAREKSKAAEAQEKILDLQQK 300
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEeeLEQLRKELEELSRQisALRKDLARLEAEVEQLEERIAQLSKE 755

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   301 LDHGRQVCLSDVciLRKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEavnsQQQEAL 380
Cdd:TIGR02168  756 LTELEAEIEELE--ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR----ERLESL 829

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   381 RKQLERERRKCEEYVKSNQELSEKLSNLQQEKEALWQEHGRFLEQLgDHVRNYKDKHHCHKAKLQKVKDRLTHELEIRNK 460
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL-EALLNERASLEEALALLRSELEELSEELRELES 908

                          250
                   ....*....|....*..
gi 394025701   461 RIKELEDETGKLQQKIE 477
Cdd:TIGR02168  909 KRSELRRELEELREKLA 925
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
231-435 1.24e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 1.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  231 AQEKLLDNARLHSSLTAEWKHCQQKVKELELEgLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHgrqvCLS 310
Cdd:COG4913   608 NRAKLAALEAELAELEEELAEAEERLEALEAE-LDALQERREALQRLAEYSWDEIDVASAEREIAELEAELER----LDA 682

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  311 DVCILRkkQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDkeeQQEAVNSQQQEALRKQLErERRK 390
Cdd:COG4913   683 SSDDLA--ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQD---RLEAAEDLARLELRALLE-ERFA 756

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 394025701  391 CEEYVKSNQELSEKLSN-LQQEKEALWQEHGRFLEQLGDHVRNYKD 435
Cdd:COG4913   757 AALGDAVERELRENLEErIDALRARLNRAEEELERAMRAFNREWPA 802
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 176-427 1.48e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.51  E-value: 1.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   176 QGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQK 255
Cdd:TIGR02168  690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER 769

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   256 VKELELEGLRQTQSLKSQQGLQEKLARE----KSKAAEAQEKILDLQQKLDHGRQvclsdvcilRKKQLEEEIKEAKSIE 331
Cdd:TIGR02168  770 LEEAEEELAEAEAEIEELEAQIEQLKEElkalREALDELRAELTLLNEEAANLRE---------RLESLERRIAATERRL 840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   332 ARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNSQQQEALRKQLERErrkcEEYVKSNQELSEKLSNLQQE 411
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSEL----EELSEELRELESKRSELRRE 916

                          250
                   ....*....|....*.
gi 394025701   412 KEALWQEHGRFLEQLG 427
Cdd:TIGR02168  917 LEELREKLAQLELRLE 932
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 115-415 2.17e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.76  E-value: 2.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   115 EIEKLKDNLMKLKESGTTDLQRAREHNQRLDEEILALRNRVRSLDSEKKYLTsgEKTSCQHQGELRELRQNLRRLQILCN 194
Cdd:TIGR02169  227 ELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELN--KKIKDLGEEEQLRVKEKIGELEAEIA 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   195 SAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELELEglrqtqslksQQ 274
Cdd:TIGR02169  305 SLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAE----------LE 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   275 GLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVclSDVCILRKKQLEEEIKEAKSIEARLQqqcqeeqqrrilldQDINE 354
Cdd:TIGR02169  375 EVDKEFAETRDELKDYREKLEKLKREINELKRE--LDRLQEELQRLSEELADLNAAIAGIE--------------AKINE 438

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 394025701   355 LQTQVRALQDKEEQQEavnsQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQEKEAL 415
Cdd:TIGR02169  439 LEEEKEDKALEIKKQE----WKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEA 495
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 254-577 2.36e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.74  E-value: 2.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   254 QKVKEL--ELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLdhgrqvclsdvcilrkKQLEEEIKEAKSIE 331
Cdd:TIGR02168  213 ERYKELkaELRELELALLVLRLEELREELEELQEELKEAEEELEELTAEL----------------QELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   332 ARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEavnsQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQE 411
Cdd:TIGR02168  277 SELEEEIEELQKELYALANEISRLEQQKQILRERLANLE----RQLEELEAQLEELESKLDELAEELAELEEKLEELKEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   412 KEALWQEHGRFLEQLGDHVRNYKDKHHCHKAKLQKVKDrLTHELEIRNKRIKELEDETGKLQQKIEMEKvfQGQIMAQND 491
Cdd:TIGR02168  353 LESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-LELQIASLNNEIERLEARLERLEDRRERLQ--QEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   492 ILLLEKRKLLEQVTDQEELICSSKCTISAFQSKASLLDKENQQLQENCLRLMQQIGLLEQIIRSIQIRREEETVITDNAA 571
Cdd:TIGR02168  430 LEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK 509


                   ....*.
gi 394025701   572 FEILKK 577
Cdd:TIGR02168  510 ALLKNQ 515
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 127-452 5.98e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.60  E-value: 5.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   127 KESGTTDLQRAREHNQRLDEEILALRNRVRSLDSEKKYLTSGEKTscqhQGELRELRQNLRRLQIlcNSAEKELRYERGR 206
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQAL----LKEKREYEGYELLKEK--EALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   207 SLDLKQHNSLLQEENIKIKIELKQAQEKLLD-NARLHSSLTAEWKHCQQKVKEL--ELEGLRQTQSLKSQ--QGLQEKLA 281
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEElNKKIKDLGEEEQLRVKEKIGELeaEIASLERSIAEKERelEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   282 REKSKAAEAQEKILDLQQKLD--HGRQVCLSDVCILRKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQ---DINELQ 356
Cdd:TIGR02169  326 KLEAEIDKLLAEIEELEREIEeeRKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKlkrEINELK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   357 TQVRALQDKEEQQeavnSQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQEkealwqehgrfLEQLGDHVRNYKDK 436
Cdd:TIGR02169  406 RELDRLQEELQRL----SEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWK-----------LEQLAADLSKYEQE 470

                          330
                   ....*....|....*.
gi 394025701   437 HHCHKAKLQKVKDRLT 452
Cdd:TIGR02169  471 LYDLKEEYDRVEKELS 486
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 133-417 8.72e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.88  E-value: 8.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  133 DLQRAREHNQRLDEeilALRNRVRSLDSEKKYLTSGEKTSCQHQGELRELRQNLRRLQiLCNSAEKELRYERGRSLDLKQ 212
Cdd:pfam17380 307 EKAREVERRRKLEE---AEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRE-LERIRQEEIAMEISRMRELER 382

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  213 HNSLLQEENIKIKIELKQAQE-KLLDNARlhSSLTAEWKHCQQKVKElELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQ 291
Cdd:pfam17380 383 LQMERQQKNERVRQELEAARKvKILEEER--QRKIQQQKVEMEQIRA-EQEEARQREVRRLEEERAREMERVRLEEQERQ 459

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  292 EKILDLQQKLDHGRQVCLSDVCILRKKQLEEEIKEA---KSIEARLQQQCQEEQQRRILLdqdiNELQTQVRALQDKEEQ 368
Cdd:pfam17380 460 QQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKileKELEERKQAMIEEERKRKLLE----KEMEERQKAIYEEERR 535

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 394025701  369 QEAvnsqqQEALRKQLE-RERRKCEEYVKSNQELSEKLSNLQQEKEALWQ 417
Cdd:pfam17380 536 REA-----EEERRKQQEmEERRRIQEQMRKATEERSRLEAMEREREMMRQ 580
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
115-415 9.13e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 9.13e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 115 EIEKLKDNLMKLKESGTTDLQRAREHNQRLDEEILALRNRVRSLDSEKKYLTSGEKTSCQHQGELRELRQNLRRLQILCN 194
Cdd:PRK03918 190 NIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIE 269

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 195 SAEKELRYERGRSLDLKQHNSlLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELELEGLRQTQSLKSQQ 274
Cdd:PRK03918 270 ELKKEIEELEEKVKELKELKE-KAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLK 348

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 275 GLQEKLAREKsKAAEAQEKILDLQQKLDHGRqvclSDVCILRKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQDINE 354
Cdd:PRK03918 349 ELEKRLEELE-ERHELYEEAKAKKEELERLK----KRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKE 423

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 394025701 355 LQTQVRALQDKEEQQEAVNSQQQEALRKQLERE-RRKCEEYVKSNQELSEKLSNLQQEKEAL 415
Cdd:PRK03918 424 LKKAIEELKKAKGKCPVCGRELTEEHRKELLEEyTAELKRIEKELKEIEEKERKLRKELREL 485
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
206-426 1.49e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.01  E-value: 1.49e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 206 RSLDLKQHNSLLQEENIKIKIELKQAQEKLLDnarlhssltaewkhCQQKVKELELEGlRQTQSLKSQQGLQEKLAREKS 285
Cdd:COG3206  169 RREEARKALEFLEEQLPELRKELEEAEAALEE--------------FRQKNGLVDLSE-EAKLLLQQLSELESQLAEARA 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 286 KAAEAQEKILDLQQKLDHGRQVCLSDVCILRKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDK 365
Cdd:COG3206  234 ELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQR 313

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 394025701 366 EEQQEAVNSQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQEKEALWQEHGRFLEQL 426
Cdd:COG3206  314 ILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRL 374
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 323-562 3.65e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.89  E-value: 3.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   323 EIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEavnsQQQEALRKQLERERRKCEEYVKSNQELS 402
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS----RQISALRKDLARLEAEVEQLEERIAQLS 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   403 EKLSNLQQEKEALWQEhgrfLEQLGDHVRNYKDKHHCHKAKLQKVKDRL---THELEIRNKRIKELEDETGKLQQKIEME 479
Cdd:TIGR02168  754 KELTELEAEIEELEER----LEEAEEELAEAEAEIEELEAQIEQLKEELkalREALDELRAELTLLNEEAANLRERLESL 829

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   480 KVFQGQIMAQNDILLLEKRKLLEQVTDQEELICSSKCTISAFQSKASLLDKENQQLQENCLRLMQQIGLLEQIIRSIQIR 559
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   ...
gi 394025701   560 REE 562
Cdd:TIGR02168  910 RSE 912
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
227-410 4.40e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 4.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  227 ELKQAQEKLLDNARLHSSLTAEWKHcQQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDL-QQKLDHGR 305
Cdd:COG4913   259 ELAERYAAARERLAELEYLRAALRL-WFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELeAQIRGNGG 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  306 QvclsdvcilRKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLD-------QDINELQTQVRALQDKEEQQEAvnsQQQE 378
Cdd:COG4913   338 D---------RLEQLEREIERLERELEERERRRARLEALLAALGlplpasaEEFAALRAEAAALLEALEEELE---ALEE 405

                         170       180       190
                  ....*....|....*....|....*....|..
gi 394025701  379 ALRKQLERERRKCEEYvksnQELSEKLSNLQQ 410
Cdd:COG4913   406 ALAEAEAALRDLRREL----RELEAEIASLER 433
46 PHA02562
endonuclease subunit; Provisional
 348-476 8.47e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 8.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 348 LDQDINELQTQVRALQDKEEQQEAVNSQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQEKE-------ALWQEHG 420
Cdd:PHA02562 186 LDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEdpsaalnKLNTAAA 265

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 394025701 421 RF---LEQLGDHVRNYKDKHHC---------HKAKLQKVKDR---LTHELEIRNKRIKELE---DETGKLQQKI 476
Cdd:PHA02562 266 KIkskIEQFQKVIKMYEKGGVCptctqqiseGPDRITKIKDKlkeLQHSLEKLDTAIDELEeimDEFNEQSKKL 339
PTZ00121 PTZ00121
MAEBL; Provisional
 196-578 1.06e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 1.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  196 AEKELRYERGRSL-DLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELELEGLRQTQSLKSQQ 274
Cdd:PTZ00121 1208 AEEERKAEEARKAeDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAE 1287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  275 glqEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSdvcilrKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQDINE 354
Cdd:PTZ00121 1288 ---EKKKADEAKKAEEKKKADEAKKKAEEAKKADEA------KKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADE 1358

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  355 LQ-TQVRALQDKEEQQEAvnSQQQEALRKQLErERRKCEEYVKSNQELSEKLSNLQQEKEAlwQEHGRFLEQLGDHVRNY 433
Cdd:PTZ00121 1359 AEaAEEKAEAAEKKKEEA--KKKADAAKKKAE-EKKKADEAKKKAEEDKKKADELKKAAAA--KKKADEAKKKAEEKKKA 1433

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  434 -------KDKHHCHKAKLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIEME----KVFQGQIMAQNDILLLEKRKLLE 502
Cdd:PTZ00121 1434 deakkkaEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADeakkKAEEAKKKADEAKKAAEAKKKAD 1513

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 394025701  503 QVTDQEELICSSKCTISAFQSKASLLDKENQQLQENCLRLMQQIGLLEQIIRSIQIRREEETVITDNAAFEILKKI 578
Cdd:PTZ00121 1514 EAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA 1589
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
253-458 1.17e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 1.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  253 QQKVKELE-LEGLRQT-QSLKSQQGLQEKLaREKSKAAEAQEKILDLQQKLDHGRQvclsdvcilRKKQLEEEIKEAKSI 330
Cdd:COG4913   248 REQIELLEpIRELAERyAAARERLAELEYL-RAALRLWFAQRRLELLEAELEELRA---------ELARLEAELERLEAR 317

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  331 EARLQQQCQEEQQRRILLD-QDINELQTQVRALQDKEEQQEAVNSQQQEALR----------KQLERERRKCEEYVKSNQ 399
Cdd:COG4913   318 LDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARLEALLAalglplpasaEEFAALRAEAAALLEALE 397

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 394025701  400 ELSEKLSNLQQEKEALWQEHGRFLEQLGDHVRNYKDKHHCHKAKLQKVKDRLTHELEIR 458
Cdd:COG4913   398 EELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLD 456
PRK12704 PRK12704
phosphodiesterase; Provisional
 317-479 1.47e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 1.47e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 317 KKQLEEEIKEAKSI-EARLQQQCQEEQQRRILLDQDI----NELQTQVRALQDKEEQqeavnsqqqeaLRKQLERERRKC 391
Cdd:PRK12704  41 KRILEEAKKEAEAIkKEALLEAKEEIHKLRNEFEKELrerrNELQKLEKRLLQKEEN-----------LDRKLELLEKRE 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 392 EEYVKSNQELSEKLSNLQQEKEalwqehgrfleqlgdhvrNYKDKHHCHKAKLQKVKdRLTHElEIRNKRIKELEDET-- 469
Cdd:PRK12704 110 EELEKKEKELEQKQQELEKKEE------------------ELEELIEEQLQELERIS-GLTAE-EAKEILLEKVEEEArh 169

                        170
                 ....*....|..
gi 394025701 470 --GKLQQKIEME 479
Cdd:PRK12704 170 eaAVLIKEIEEE 181
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 24-292 2.90e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.08  E-value: 2.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  24 ERRTLAEALGLVDSTLESRRDPNSSLQKEFPQHQDEDQSRAAAPQDcLLRDVECIAQKLEASLEEIHRgareprEEREQR 103
Cdd:COG1196  254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR-LEQDIARLEERRRELEERLEE------LEEELA 326

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 104 TLGDALENARLEIEKLKDNLMKLKESGTTDLQRAREHNQRLDEEILALRNRVRSLDSEKKyltsgektscqhqgELRELR 183
Cdd:COG1196  327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE--------------ELLEAL 392

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 184 QNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELELEG 263
Cdd:COG1196  393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                        250       260
                 ....*....|....*....|....*....
gi 394025701 264 LRQTQSLKSQQGLQEKLAREKSKAAEAQE 292
Cdd:COG1196  473 ALLEAALAELLEELAEAAARLLLLLEAEA 501
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
227-426 3.81e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.52  E-value: 3.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 227 ELKQAQEKLLD-NARLHSSLTAEWKHCQQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGR 305
Cdd:COG4717   50 RLEKEADELFKpQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701 306 QvclsdvcILRKKQLEEEIKEaksIEARLQQqcqeeqqrrilLDQDINELQTQVRALQDKEEQQEAVNSQQQEALRKQLE 385
Cdd:COG4717  130 L-------YQELEALEAELAE---LPERLEE-----------LEERLEELRELEEELEELEAELAELQEELEELLEQLSL 188

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 394025701 386 RERRKCEEYVKSNQELSEKLSNLQQEKEALWQEHGRFLEQL 426
Cdd:COG4717  189 ATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEL 229
PTZ00121 PTZ00121
MAEBL; Provisional
 79-485 6.21e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.12  E-value: 6.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701   79 AQKLEASLEEIHRGAREPREEREQRTLGDalENARLEIEKLKDNLMKLKESGTTDLQRAREHNQRLD------EEILALR 152
Cdd:PTZ00121 1317 ADEAKKKAEEAKKKADAAKKKAEEAKKAA--EAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADaakkkaEEKKKAD 1394

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  153 NRVRSLDSEKKYLTSGEKTSCQHQG--ELRELRQNLRRLQILCNSAEKELRYERGRsldlKQHNSLLQEENIKIKIELKQ 230
Cdd:PTZ00121 1395 EAKKKAEEDKKKADELKKAAAAKKKadEAKKKAEEKKKADEAKKKAEEAKKADEAK----KKAEEAKKAEEAKKKAEEAK 1470

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  231 AQEKL---LDNARLHSSLTAEWKHCQQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQE----KILDLQQKLDH 303
Cdd:PTZ00121 1471 KADEAkkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKadeaKKAEEKKKADE 1550

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  304 GRQVC-LSDVCILRKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNSQQ---QEA 379
Cdd:PTZ00121 1551 LKKAEeLKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElkkAEE 1630

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 394025701  380 LRKQLERERRKCEEYVKSNQEL--SEKLSNLQQEKEALWQEHG---------------RFLEQLGDHVRNYKDKHHCHKA 442
Cdd:PTZ00121 1631 EKKKVEQLKKKEAEEKKKAEELkkAEEENKIKAAEEAKKAEEDkkkaeeakkaeedekKAAEALKKEAEEAKKAEELKKK 1710

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*
gi 394025701  443 KLQKVK--DRLTHELEIRNKRIKELEDETGKLQQKIEMEKVFQGQ 485
Cdd:PTZ00121 1711 EAEEKKkaEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEE 1755
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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