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Conserved domains on  [gi|281371344|ref|NP_001163901|]
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adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform 1 [Mus musculus]

Protein Classification

DMT family transporter( domain architecture ID 12093821)

DMT (drug/metabolite transporter) family transporter is an inner membrane protein involved in the transport of one or more of a variety of substrates such as amino acids, drugs, metabolites, and sugar phosphates, among others; such as yeast UDP-N-acetylglucosamine transporter YEA4 and vertebrate UDP-xylose and UDP-N-acetylglucosamine transporter

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UAA pfam08449
UAA transporter family; This family includes transporters with a specificity for ...
 48-339 1.52e-99

UAA transporter family; This family includes transporters with a specificity for UDP-N-acetylglucosamine.


:

Pssm-ID: 462479 [Multi-domain]  Cd Length: 307  Bit Score: 297.29  E-value: 1.52e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371344   48 QFLICVAGVFVFYLIYGYLQELIFSVEGfKPYGWYLTLVQFAFYSVFGLIELQL----TQDRRRRIPGKTYMLIAFLTVG 123
Cdd:pfam08449   1 QFLLAVSGVFGGCCSNGVLQELIMKVEP-GPFGNLLTFAQFLFYALEGLPESIDiftsKFLKPRKIPLKTYVILVALFFI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371344  124 TMGLSNTSLGY-LNYPTQVIFKCCKLIPVMLGGVFIQGKRYNLADVSAAVCMSLGLIWFTL-------ADSTIAPNFNLT 195
Cdd:pfam08449  80 TSVLNNEALKYdISYPTHIIFRSSKLIPVMIMGILILGKRYSKLQYLSAFLVTLGIIIFTLfsakdkvADSVVSPNFFLI 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371344  196 GVMLISLALCADAVIGNVQEKAMKLHNASNSEMVLYSYSIGFVYILLglsCTSGLGPAVAFCSKNPVGTY-------GYA 268
Cdd:pfam08449 160 GIAMLSGALLLDAFLGNYQEKTYKKYGKHSKEMLFYSHLLSLPFFLL---LQGDLFSAVQFCSQSPDKAVlslpsmlFYL 236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 281371344  269 FLFSLTGYFGISFVLALIKIFGALLAVTVTTGRKAMTVVLSFLFFAKPFTFQYIWSGLLVVLGIFLNVYSK 339
Cdd:pfam08449 237 LLNVLTQYVCIRGVFILISEFGALTVTLVTTLRKFVSLLLSILLFGNPFTLQHWVGTLLVFLGTFLYSYSK 307
 
Name Accession Description Interval E-value
UAA pfam08449
UAA transporter family; This family includes transporters with a specificity for ...
 48-339 1.52e-99

UAA transporter family; This family includes transporters with a specificity for UDP-N-acetylglucosamine.


Pssm-ID: 462479 [Multi-domain]  Cd Length: 307  Bit Score: 297.29  E-value: 1.52e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371344   48 QFLICVAGVFVFYLIYGYLQELIFSVEGfKPYGWYLTLVQFAFYSVFGLIELQL----TQDRRRRIPGKTYMLIAFLTVG 123
Cdd:pfam08449   1 QFLLAVSGVFGGCCSNGVLQELIMKVEP-GPFGNLLTFAQFLFYALEGLPESIDiftsKFLKPRKIPLKTYVILVALFFI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371344  124 TMGLSNTSLGY-LNYPTQVIFKCCKLIPVMLGGVFIQGKRYNLADVSAAVCMSLGLIWFTL-------ADSTIAPNFNLT 195
Cdd:pfam08449  80 TSVLNNEALKYdISYPTHIIFRSSKLIPVMIMGILILGKRYSKLQYLSAFLVTLGIIIFTLfsakdkvADSVVSPNFFLI 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371344  196 GVMLISLALCADAVIGNVQEKAMKLHNASNSEMVLYSYSIGFVYILLglsCTSGLGPAVAFCSKNPVGTY-------GYA 268
Cdd:pfam08449 160 GIAMLSGALLLDAFLGNYQEKTYKKYGKHSKEMLFYSHLLSLPFFLL---LQGDLFSAVQFCSQSPDKAVlslpsmlFYL 236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 281371344  269 FLFSLTGYFGISFVLALIKIFGALLAVTVTTGRKAMTVVLSFLFFAKPFTFQYIWSGLLVVLGIFLNVYSK 339
Cdd:pfam08449 237 LLNVLTQYVCIRGVFILISEFGALTVTLVTTLRKFVSLLLSILLFGNPFTLQHWVGTLLVFLGTFLYSYSK 307
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 81-339 7.96e-03

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 37.90  E-value: 7.96e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371344  81 WYLTLVQFAFYSVFGLIELQLTQDRRRRIPGKTYMLIAFLTVGTMGLSNTSLGYLNYPTQVIFKCCKLIPVMLGGVFIQG 160
Cdd:COG0697   36 FLRFLLAALLLLPLLLLRGRRLPPLSRRDWLLLLLRGLLGLALAFLLFFLALQYTPAALAALLLALAPLFVALLAALLLG 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371344 161 KRYNLADVSAAVCMSLGLIWFTLADSTIAPNFNL-TGVMLISLALCAdavIGNVQEKAMkLHNASNSEMVLYSYSIGFVY 239
Cdd:COG0697  116 ERLSRRRWLGLLLGFAGVLLIVGPGGGGGGGSLLgDLLALLAALSWA---LYTVLTRRL-SRRLDPLTLTFWQMLVGALL 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371344 240 ILLGLSCTSGLGPAvafcskNPVGTYGYAFLFSLTGYFGISFVLALIKIFGALLAVTVTTGRKAMTVVLSFLFFAKPFTF 319
Cdd:COG0697  192 LLPLALLTGLPLPL------SAAAWLALLYLGLFGTALAYLLWFRALRRLGASRAAPLTYLEPVFAVLLGWLLLGEPLTP 265

                        250       260
                 ....*....|....*....|
gi 281371344 320 QYIWSGLLVVLGIFLNVYSK 339
Cdd:COG0697  266 LQLLGAALILAGVLLAALRE 285
 
Name Accession Description Interval E-value
UAA pfam08449
UAA transporter family; This family includes transporters with a specificity for ...
 48-339 1.52e-99

UAA transporter family; This family includes transporters with a specificity for UDP-N-acetylglucosamine.


Pssm-ID: 462479 [Multi-domain]  Cd Length: 307  Bit Score: 297.29  E-value: 1.52e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371344   48 QFLICVAGVFVFYLIYGYLQELIFSVEGfKPYGWYLTLVQFAFYSVFGLIELQL----TQDRRRRIPGKTYMLIAFLTVG 123
Cdd:pfam08449   1 QFLLAVSGVFGGCCSNGVLQELIMKVEP-GPFGNLLTFAQFLFYALEGLPESIDiftsKFLKPRKIPLKTYVILVALFFI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371344  124 TMGLSNTSLGY-LNYPTQVIFKCCKLIPVMLGGVFIQGKRYNLADVSAAVCMSLGLIWFTL-------ADSTIAPNFNLT 195
Cdd:pfam08449  80 TSVLNNEALKYdISYPTHIIFRSSKLIPVMIMGILILGKRYSKLQYLSAFLVTLGIIIFTLfsakdkvADSVVSPNFFLI 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371344  196 GVMLISLALCADAVIGNVQEKAMKLHNASNSEMVLYSYSIGFVYILLglsCTSGLGPAVAFCSKNPVGTY-------GYA 268
Cdd:pfam08449 160 GIAMLSGALLLDAFLGNYQEKTYKKYGKHSKEMLFYSHLLSLPFFLL---LQGDLFSAVQFCSQSPDKAVlslpsmlFYL 236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 281371344  269 FLFSLTGYFGISFVLALIKIFGALLAVTVTTGRKAMTVVLSFLFFAKPFTFQYIWSGLLVVLGIFLNVYSK 339
Cdd:pfam08449 237 LLNVLTQYVCIRGVFILISEFGALTVTLVTTLRKFVSLLLSILLFGNPFTLQHWVGTLLVFLGTFLYSYSK 307
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 81-339 7.96e-03

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 37.90  E-value: 7.96e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371344  81 WYLTLVQFAFYSVFGLIELQLTQDRRRRIPGKTYMLIAFLTVGTMGLSNTSLGYLNYPTQVIFKCCKLIPVMLGGVFIQG 160
Cdd:COG0697   36 FLRFLLAALLLLPLLLLRGRRLPPLSRRDWLLLLLRGLLGLALAFLLFFLALQYTPAALAALLLALAPLFVALLAALLLG 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371344 161 KRYNLADVSAAVCMSLGLIWFTLADSTIAPNFNL-TGVMLISLALCAdavIGNVQEKAMkLHNASNSEMVLYSYSIGFVY 239
Cdd:COG0697  116 ERLSRRRWLGLLLGFAGVLLIVGPGGGGGGGSLLgDLLALLAALSWA---LYTVLTRRL-SRRLDPLTLTFWQMLVGALL 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371344 240 ILLGLSCTSGLGPAvafcskNPVGTYGYAFLFSLTGYFGISFVLALIKIFGALLAVTVTTGRKAMTVVLSFLFFAKPFTF 319
Cdd:COG0697  192 LLPLALLTGLPLPL------SAAAWLALLYLGLFGTALAYLLWFRALRRLGASRAAPLTYLEPVFAVLLGWLLLGEPLTP 265

                        250       260
                 ....*....|....*....|
gi 281371344 320 QYIWSGLLVVLGIFLNVYSK 339
Cdd:COG0697  266 LQLLGAALILAGVLLAALRE 285
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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