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Conserved domains on  [gi|258645133|ref|NP_001158270|]
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solute carrier family 38 member 10 isoform 2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SLC5-6-like_sbd super family cl00456
Solute carrier families 5 and 6-like; solute binding domain; This superfamily includes the ...
 6-381 1.14e-52

Solute carrier families 5 and 6-like; solute binding domain; This superfamily includes the solute-binding domain of SLC5 proteins (also called the sodium/glucose cotransporters or solute sodium symporters), SLC6 proteins (also called the sodium- and chloride-dependent neurotransmitter transporters or Na+/Cl--dependent transporters), and nucleobase-cation-symport-1 (NCS1) transporters. SLC5s co-transport Na+ with sugars, amino acids, inorganic ions or vitamins. SLC6s include Na+/Cl--dependent plasma membrane transporters for the monoamine neurotransmitters serotonin, dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. Members of this superfamily are important in human physiology and disease. They contain a functional core of 10 transmembrane helices (TMs): an inverted structural repeat, TMs1-5 and TMs6-10; TMs numbered to conform to the SLC6 Aquifex aeolicus LeuT.


The actual alignment was detected with superfamily member pfam01490:

Pssm-ID: 444915  Cd Length: 410  Bit Score: 190.59  E-value: 1.14e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133     6 TSKWGLITNVVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSA-----SLSKRRTYAGLAFHAYGKA 80
Cdd:pfam01490    3 ISAWQAVFNLINAIIGAGVLSLPYAFKQLGWIPGLILLLIVGLISLYTAHLLVRCSkevpvTGKRNKSYGDLGYRLLGPK 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133    81 GKMLVETSMIGLMLGSCITFYVVIGDLGSNFFAPLLGlqvTRTVRVFLLFAVSLFIVLPLSLQRNMMA-SIQS-FSAMAL 158
Cdd:pfam01490   83 GRLLILFAILLNLFGVCISYLIFAGDNLPAIFDSFFD---TCPISLVYFIIIFGLIFIPLSFIPNLSAlSILSlLAAVSS 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133   159 LFYTVFMFVIVLSSLKHGLFSGQWLRQVSYIRWEGVFRCVPIFGMSFACQSQVLPTYDSLDEPSV-KTMSSIFASSLNVV 237
Cdd:pfam01490  160 LYYIVILVLSVAEGIVLTAQGVGHLGSKTNIKLAGTFLAIGIIVFAFEGHAVLLPIQNEMKNPSKfKAMTKILLTAIIIA 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133   238 TAFYVMVGFFGYVSFTDATTGNVLIHFP-SNPVTEMIRVGFVMSVAVGFPMMILPCRQALNTLLFEQQqkdgTFAAGGYM 316
Cdd:pfam01490  240 TVLYILIGLVGYLAFGDNVKGNILLNLPkSAWLIDIANLLLVLHVILSFPLQLFPIRQIVENLLFRKE----APFGASGK 315

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 258645133   317 PP----LRFKVLTLSVVFGTMVGGVMIPNVETILGFTGATMGSLICFICPALIYKKAHKNAPSAQVVLW 381
Cdd:pfam01490  316 NNpkskLLRVVIRSGLVVITYLIAISVPFFGDLLSLVGATSCAPLSFILPPLFHLKLKKTKKKSQEKLW 384
PTZ00121 super family cl31754
MAEBL; Provisional
 407-767 1.35e-07

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.30  E-value: 1.35e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  407 QEARSghrgdAEGAMKVEAARLSVQDPVVVVA---EDSQ--EKLKPAEDKEVLEQA----QIKGPVDVPGGEAPKEKQEA 477
Cdd:PTZ00121 1131 EEARK-----AEDARKAEEARKAEDAKRVEIArkaEDARkaEEARKAEDAKKAEAArkaeEVRKAEELRKAEDARKAEAA 1205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  478 AQLDRPGQGIAVPMGE-AHRHEPPIPHDKVVVDEGQDQEGPEEKKPPP-RLPDEGDPAGRGQGAPPLPESEKEKQEPERG 555
Cdd:PTZ00121 1206 RKAEEERKAEEARKAEdAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEiRKFEEARMAHFARRQAAIKAEEARKADELKK 1285

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  556 GEGKRPGQVLAvgETEHPQKVPEANgqppvqprkedsrpgnrdpQPAAQARDSVELKALAaddgrEPAQKAGGALWKPVE 635
Cdd:PTZ00121 1286 AEEKKKADEAK--KAEEKKKADEAK-------------------KKAEEAKKADEAKKKA-----EEAKKKADAAKKKAE 1339

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  636 SAAESDAGGKAGLPVQRPEAAEQREKKEAEQQGGDQAGSKLEaEIKKLVAEAGRAEMLdhavllqviQEQQVQQKRLLDQ 715
Cdd:PTZ00121 1340 EAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD-AAKKKAEEKKKADEA---------KKKAEEDKKKADE 1409

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 258645133  716 QEKllavIEEQHKEIRQQRQEGEE----DKPKPDVQPEPGVAVLRGQEEEAEHAGE 767
Cdd:PTZ00121 1410 LKK----AAAAKKKADEAKKKAEEkkkaDEAKKKAEEAKKADEAKKKAEEAKKAEE 1461
PTZ00449 super family cl33186
104 kDa microneme/rhoptry antigen; Provisional
 710-969 6.78e-05

104 kDa microneme/rhoptry antigen; Provisional


The actual alignment was detected with superfamily member PTZ00449:

Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 46.99  E-value: 6.78e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  710 KRLLDQQEKLLAVIEEQHKEIRQQRQEGEEDKPKPDVQPEpgvavlrGQEEEAEHAGETLGDDPSQ----PLQPVLGAPR 785
Cdd:PTZ00449  486 KKLIKKSKKKLAPIEEEDSDKHDEPPEGPEASGLPPKAPG-------DKEGEEGEHEDSKESDEPKeggkPGETKEGEVG 558

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  786 GRPAPSQdmgQHLPGEVKVLPGRdladlPAGGSETEPQGAPIDLR--EDPKAAIKAAGAGKELVPGDLEAVHKAAPPEVP 863
Cdd:PTZ00449  559 KKPGPAK---EHKPSKIPTLSKK-----PEFPKDPKHPKDPEEPKkpKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESP 630

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  864 KSPEKQVAKavagQRqdvfgEGSEERKETGKEAMAPGA-DTQKEAVQPLVGAEAKDTKSRQSGPTKAPVQTQA------- 935
Cdd:PTZ00449  631 KSPKRPPPP----QR-----PSSPERPEGPKIIKSPKPpKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVldesfes 701

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 258645133  936 ---KFHPEPQAIFDTGQGSHPEVRSEAPRAVHIPPEE 969
Cdd:PTZ00449  702 ilkETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGD 738
 
Name Accession Description Interval E-value
Aa_trans pfam01490
Transmembrane amino acid transporter protein; This transmembrane region is found in many amino ...
 6-381 1.14e-52

Transmembrane amino acid transporter protein; This transmembrane region is found in many amino acid transporters including UNC-47 and MTR. UNC-47 encodes a vesicular amino butyric acid (GABA) transporter, (VGAT). UNC-47 is predicted to have 10 transmembrane domains. MTR is a N system amino acid transporter system protein involved in methyltryptophan resistance. Other members of this family include proline transporters and amino acid permeases.


Pssm-ID: 279788  Cd Length: 410  Bit Score: 190.59  E-value: 1.14e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133     6 TSKWGLITNVVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSA-----SLSKRRTYAGLAFHAYGKA 80
Cdd:pfam01490    3 ISAWQAVFNLINAIIGAGVLSLPYAFKQLGWIPGLILLLIVGLISLYTAHLLVRCSkevpvTGKRNKSYGDLGYRLLGPK 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133    81 GKMLVETSMIGLMLGSCITFYVVIGDLGSNFFAPLLGlqvTRTVRVFLLFAVSLFIVLPLSLQRNMMA-SIQS-FSAMAL 158
Cdd:pfam01490   83 GRLLILFAILLNLFGVCISYLIFAGDNLPAIFDSFFD---TCPISLVYFIIIFGLIFIPLSFIPNLSAlSILSlLAAVSS 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133   159 LFYTVFMFVIVLSSLKHGLFSGQWLRQVSYIRWEGVFRCVPIFGMSFACQSQVLPTYDSLDEPSV-KTMSSIFASSLNVV 237
Cdd:pfam01490  160 LYYIVILVLSVAEGIVLTAQGVGHLGSKTNIKLAGTFLAIGIIVFAFEGHAVLLPIQNEMKNPSKfKAMTKILLTAIIIA 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133   238 TAFYVMVGFFGYVSFTDATTGNVLIHFP-SNPVTEMIRVGFVMSVAVGFPMMILPCRQALNTLLFEQQqkdgTFAAGGYM 316
Cdd:pfam01490  240 TVLYILIGLVGYLAFGDNVKGNILLNLPkSAWLIDIANLLLVLHVILSFPLQLFPIRQIVENLLFRKE----APFGASGK 315

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 258645133   317 PP----LRFKVLTLSVVFGTMVGGVMIPNVETILGFTGATMGSLICFICPALIYKKAHKNAPSAQVVLW 381
Cdd:pfam01490  316 NNpkskLLRVVIRSGLVVITYLIAISVPFFGDLLSLVGATSCAPLSFILPPLFHLKLKKTKKKSQEKLW 384
PTZ00206 PTZ00206
amino acid transporter; Provisional
 14-366 1.75e-25

amino acid transporter; Provisional


Pssm-ID: 240313  Cd Length: 467  Bit Score: 111.50  E-value: 1.75e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133   14 NVVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLAFHAYGKAGKMLVETSMIGLM 93
Cdd:PTZ00206   68 NIASSTVGAGIVGLPSAANSSGLVMAMIYLIIITAMTIFSIYALGVAADKTNIRTYEGVARVLLGPWGSYYVAATRAFHG 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133   94 LGSCITFYVVIGDLGSnffAPLLGLQV-----TRTVRVFLLFAVSLFIVLPLSLQRNMmASIQSFSAMALLFYTVFMFVI 168
Cdd:PTZ00206  148 FSACVAYVISVGDILS---ATLKGTNApdflkQKSGNRLLTSLMWLCFMLPLVIPRHI-DSLRYVSTIAVSFMVYLVIVI 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  169 VLSSLKHGLfsGQWLRQVSY--------IRWEGVFRCVP---IFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVV 237
Cdd:PTZ00206  224 VVHSCMNGL--PENIKNVSVgkddnaeiILFNSGNRAIEglgVFIFAYVFQITAYEVYMDMTNRSVGKFVLASTIAMGMC 301

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  238 TAFYVMVGFFGYVSFTDATTGNVLIHFpsNPVTE-MIRVGFV---MSVAVGFPMMILPCRQALNTLLFEQQQKDGTFAAG 313
Cdd:PTZ00206  302 FTMYVLTAFFGYMDFGRNVTGSVLLMY--DPVNEpAIMVGFVgvlVKLFVSYALLGMACRNALYDVIGWDARKVAFWKHC 379

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 258645133  314 gympplrFKVLTLSVVFgtMVGGVMIPNVETILGFTGATMGSLICFICPALIY 366
Cdd:PTZ00206  380 -------IAVVTLSVVM--LLCGLFIPKINTVLGFAGSISGGLLGFILPALLF 423
PTZ00121 PTZ00121
MAEBL; Provisional
 407-767 1.35e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.30  E-value: 1.35e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  407 QEARSghrgdAEGAMKVEAARLSVQDPVVVVA---EDSQ--EKLKPAEDKEVLEQA----QIKGPVDVPGGEAPKEKQEA 477
Cdd:PTZ00121 1131 EEARK-----AEDARKAEEARKAEDAKRVEIArkaEDARkaEEARKAEDAKKAEAArkaeEVRKAEELRKAEDARKAEAA 1205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  478 AQLDRPGQGIAVPMGE-AHRHEPPIPHDKVVVDEGQDQEGPEEKKPPP-RLPDEGDPAGRGQGAPPLPESEKEKQEPERG 555
Cdd:PTZ00121 1206 RKAEEERKAEEARKAEdAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEiRKFEEARMAHFARRQAAIKAEEARKADELKK 1285

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  556 GEGKRPGQVLAvgETEHPQKVPEANgqppvqprkedsrpgnrdpQPAAQARDSVELKALAaddgrEPAQKAGGALWKPVE 635
Cdd:PTZ00121 1286 AEEKKKADEAK--KAEEKKKADEAK-------------------KKAEEAKKADEAKKKA-----EEAKKKADAAKKKAE 1339

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  636 SAAESDAGGKAGLPVQRPEAAEQREKKEAEQQGGDQAGSKLEaEIKKLVAEAGRAEMLdhavllqviQEQQVQQKRLLDQ 715
Cdd:PTZ00121 1340 EAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD-AAKKKAEEKKKADEA---------KKKAEEDKKKADE 1409

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 258645133  716 QEKllavIEEQHKEIRQQRQEGEE----DKPKPDVQPEPGVAVLRGQEEEAEHAGE 767
Cdd:PTZ00121 1410 LKK----AAAAKKKADEAKKKAEEkkkaDEAKKKAEEAKKADEAKKKAEEAKKAEE 1461
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 710-969 6.78e-05

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 46.99  E-value: 6.78e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  710 KRLLDQQEKLLAVIEEQHKEIRQQRQEGEEDKPKPDVQPEpgvavlrGQEEEAEHAGETLGDDPSQ----PLQPVLGAPR 785
Cdd:PTZ00449  486 KKLIKKSKKKLAPIEEEDSDKHDEPPEGPEASGLPPKAPG-------DKEGEEGEHEDSKESDEPKeggkPGETKEGEVG 558

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  786 GRPAPSQdmgQHLPGEVKVLPGRdladlPAGGSETEPQGAPIDLR--EDPKAAIKAAGAGKELVPGDLEAVHKAAPPEVP 863
Cdd:PTZ00449  559 KKPGPAK---EHKPSKIPTLSKK-----PEFPKDPKHPKDPEEPKkpKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESP 630

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  864 KSPEKQVAKavagQRqdvfgEGSEERKETGKEAMAPGA-DTQKEAVQPLVGAEAKDTKSRQSGPTKAPVQTQA------- 935
Cdd:PTZ00449  631 KSPKRPPPP----QR-----PSSPERPEGPKIIKSPKPpKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVldesfes 701

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 258645133  936 ---KFHPEPQAIFDTGQGSHPEVRSEAPRAVHIPPEE 969
Cdd:PTZ00449  702 ilkETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGD 738
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 433-601 1.01e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 46.30  E-value: 1.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  433 PVVVVAEDSQEKLKPAEDK---EVLEQAQIKGPVDVPGGEAPKEKQEAaQLDRPGQGIAvPMGEAHRHE------PPIPH 503
Cdd:NF033839  309 EVKPEPETPKPEVKPQLEKpkpEVKPQPEKPKPEVKPQLETPKPEVKP-QPEKPKPEVK-PQPEKPKPEvkpqpeTPKPE 386

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  504 DKVVVDEGQDQEGPEEKKPPPRL---PDEGDPAGRGQGAPPLPE----SEKEKQEPERGGEGKRPgQVLAVGETEHPQKV 576
Cdd:NF033839  387 VKPQPEKPKPEVKPQPEKPKPEVkpqPEKPKPEVKPQPEKPKPEvkpqPEKPKPEVKPQPEKPKP-EVKPQPETPKPEVK 465

                         170       180
                  ....*....|....*....|....*.
gi 258645133  577 PEANG-QPPVQPRKEDSRPGNRDPQP 601
Cdd:NF033839  466 PQPEKpKPEVKPQPEKPKPDNSKPQA 491
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 505-777 3.21e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 41.52  E-value: 3.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133   505 KVVVDEGQD--QEGPEEKKPPPRLPDEGDPAGRGQGAPPLPESEKEKQEPERGGEGKRPGQVLAVGETEHPQKVPEANGQ 582
Cdd:TIGR00927  632 KGDVAEAEHtgERTGEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAERKGEQEGEGEIEAKEADHKGETE 711

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133   583 PPVQPRKEDSRPGNRDPQPAAQardsvelkalAADDGREPAQKAGGalwkpvESAAESDAGGKAGLPVQRPEAAEQREKK 662
Cdd:TIGR00927  712 AEEVEHEGETEAEGTEDEGEIE----------TGEEGEEVEDEGEG------EAEGKHEVETEGDRKETEHEGETEAEGK 775

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133   663 EAEQQGGDQAGSKLEA---EIKKLVAEAGRAEMLDHAVLLQVIQEQQVQQKRLLDQQEKlLAVIEEQHKEIRQQRQ--EG 737
Cdd:TIGR00927  776 EDEDEGEIQAGEDGEMkgdEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGE-QELNAENQGEAKQDEKgvDG 854

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 258645133   738 EEDKPKPDVQPEPGVAVLRGQEEEAEHAGETLGDDPSQPL 777
Cdd:TIGR00927  855 GGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPL 894
 
Name Accession Description Interval E-value
Aa_trans pfam01490
Transmembrane amino acid transporter protein; This transmembrane region is found in many amino ...
 6-381 1.14e-52

Transmembrane amino acid transporter protein; This transmembrane region is found in many amino acid transporters including UNC-47 and MTR. UNC-47 encodes a vesicular amino butyric acid (GABA) transporter, (VGAT). UNC-47 is predicted to have 10 transmembrane domains. MTR is a N system amino acid transporter system protein involved in methyltryptophan resistance. Other members of this family include proline transporters and amino acid permeases.


Pssm-ID: 279788  Cd Length: 410  Bit Score: 190.59  E-value: 1.14e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133     6 TSKWGLITNVVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSA-----SLSKRRTYAGLAFHAYGKA 80
Cdd:pfam01490    3 ISAWQAVFNLINAIIGAGVLSLPYAFKQLGWIPGLILLLIVGLISLYTAHLLVRCSkevpvTGKRNKSYGDLGYRLLGPK 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133    81 GKMLVETSMIGLMLGSCITFYVVIGDLGSNFFAPLLGlqvTRTVRVFLLFAVSLFIVLPLSLQRNMMA-SIQS-FSAMAL 158
Cdd:pfam01490   83 GRLLILFAILLNLFGVCISYLIFAGDNLPAIFDSFFD---TCPISLVYFIIIFGLIFIPLSFIPNLSAlSILSlLAAVSS 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133   159 LFYTVFMFVIVLSSLKHGLFSGQWLRQVSYIRWEGVFRCVPIFGMSFACQSQVLPTYDSLDEPSV-KTMSSIFASSLNVV 237
Cdd:pfam01490  160 LYYIVILVLSVAEGIVLTAQGVGHLGSKTNIKLAGTFLAIGIIVFAFEGHAVLLPIQNEMKNPSKfKAMTKILLTAIIIA 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133   238 TAFYVMVGFFGYVSFTDATTGNVLIHFP-SNPVTEMIRVGFVMSVAVGFPMMILPCRQALNTLLFEQQqkdgTFAAGGYM 316
Cdd:pfam01490  240 TVLYILIGLVGYLAFGDNVKGNILLNLPkSAWLIDIANLLLVLHVILSFPLQLFPIRQIVENLLFRKE----APFGASGK 315

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 258645133   317 PP----LRFKVLTLSVVFGTMVGGVMIPNVETILGFTGATMGSLICFICPALIYKKAHKNAPSAQVVLW 381
Cdd:pfam01490  316 NNpkskLLRVVIRSGLVVITYLIAISVPFFGDLLSLVGATSCAPLSFILPPLFHLKLKKTKKKSQEKLW 384
PTZ00206 PTZ00206
amino acid transporter; Provisional
 14-366 1.75e-25

amino acid transporter; Provisional


Pssm-ID: 240313  Cd Length: 467  Bit Score: 111.50  E-value: 1.75e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133   14 NVVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLAFHAYGKAGKMLVETSMIGLM 93
Cdd:PTZ00206   68 NIASSTVGAGIVGLPSAANSSGLVMAMIYLIIITAMTIFSIYALGVAADKTNIRTYEGVARVLLGPWGSYYVAATRAFHG 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133   94 LGSCITFYVVIGDLGSnffAPLLGLQV-----TRTVRVFLLFAVSLFIVLPLSLQRNMmASIQSFSAMALLFYTVFMFVI 168
Cdd:PTZ00206  148 FSACVAYVISVGDILS---ATLKGTNApdflkQKSGNRLLTSLMWLCFMLPLVIPRHI-DSLRYVSTIAVSFMVYLVIVI 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  169 VLSSLKHGLfsGQWLRQVSY--------IRWEGVFRCVP---IFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVV 237
Cdd:PTZ00206  224 VVHSCMNGL--PENIKNVSVgkddnaeiILFNSGNRAIEglgVFIFAYVFQITAYEVYMDMTNRSVGKFVLASTIAMGMC 301

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  238 TAFYVMVGFFGYVSFTDATTGNVLIHFpsNPVTE-MIRVGFV---MSVAVGFPMMILPCRQALNTLLFEQQQKDGTFAAG 313
Cdd:PTZ00206  302 FTMYVLTAFFGYMDFGRNVTGSVLLMY--DPVNEpAIMVGFVgvlVKLFVSYALLGMACRNALYDVIGWDARKVAFWKHC 379

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 258645133  314 gympplrFKVLTLSVVFgtMVGGVMIPNVETILGFTGATMGSLICFICPALIY 366
Cdd:PTZ00206  380 -------IAVVTLSVVM--LLCGLFIPKINTVLGFAGSISGGLLGFILPALLF 423
PTZ00121 PTZ00121
MAEBL; Provisional
 407-767 1.35e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.30  E-value: 1.35e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  407 QEARSghrgdAEGAMKVEAARLSVQDPVVVVA---EDSQ--EKLKPAEDKEVLEQA----QIKGPVDVPGGEAPKEKQEA 477
Cdd:PTZ00121 1131 EEARK-----AEDARKAEEARKAEDAKRVEIArkaEDARkaEEARKAEDAKKAEAArkaeEVRKAEELRKAEDARKAEAA 1205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  478 AQLDRPGQGIAVPMGE-AHRHEPPIPHDKVVVDEGQDQEGPEEKKPPP-RLPDEGDPAGRGQGAPPLPESEKEKQEPERG 555
Cdd:PTZ00121 1206 RKAEEERKAEEARKAEdAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEiRKFEEARMAHFARRQAAIKAEEARKADELKK 1285

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  556 GEGKRPGQVLAvgETEHPQKVPEANgqppvqprkedsrpgnrdpQPAAQARDSVELKALAaddgrEPAQKAGGALWKPVE 635
Cdd:PTZ00121 1286 AEEKKKADEAK--KAEEKKKADEAK-------------------KKAEEAKKADEAKKKA-----EEAKKKADAAKKKAE 1339

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  636 SAAESDAGGKAGLPVQRPEAAEQREKKEAEQQGGDQAGSKLEaEIKKLVAEAGRAEMLdhavllqviQEQQVQQKRLLDQ 715
Cdd:PTZ00121 1340 EAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD-AAKKKAEEKKKADEA---------KKKAEEDKKKADE 1409

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 258645133  716 QEKllavIEEQHKEIRQQRQEGEE----DKPKPDVQPEPGVAVLRGQEEEAEHAGE 767
Cdd:PTZ00121 1410 LKK----AAAAKKKADEAKKKAEEkkkaDEAKKKAEEAKKADEAKKKAEEAKKAEE 1461
PTZ00121 PTZ00121
MAEBL; Provisional
 417-767 8.79e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 8.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  417 AEGAMKVEAARLSVQDPvvvvAEDSQEKLKPAEDKEVLEQAQIKGPVDVPGGEAPKEKQEAAQLDRPGQGIAvpmgEAHR 496
Cdd:PTZ00121 1387 AEEKKKADEAKKKAEED----KKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAE----EAKK 1458

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  497 HE--PPIPHDKVVVDEGQDQegPEEKKPPPRLPDEGDPAGRGQGAPPLPESEKEKQEPERGGEGKRPGQVLAvgETEHPQ 574
Cdd:PTZ00121 1459 AEeaKKKAEEAKKADEAKKK--AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAK--KAEEAK 1534

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  575 KVPEANGQPPVQP----RKEDSRPGNRDPQPAAQARDSVELKALAADDGrEPAQKAGGALWKPVESAAESDAGGKAGLPV 650
Cdd:PTZ00121 1535 KADEAKKAEEKKKadelKKAEELKKAEEKKKAEEAKKAEEDKNMALRKA-EEAKKAEEARIEEVMKLYEEEKKMKAEEAK 1613

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  651 QRPEA---AEQREKKEAEQQGGDQAGSKLEAEIKKlvAEAGRAEMLDHAVLLQVIQEQQVQQKRLLDQ----------QE 717
Cdd:PTZ00121 1614 KAEEAkikAEELKKAEEEKKKVEQLKKKEAEEKKK--AEELKKAEEENKIKAAEEAKKAEEDKKKAEEakkaeedekkAA 1691

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 258645133  718 KLLAVIEEQHKEIRQQRQEGEEDKPKPD-VQPEPGVAVL------RGQEEEAEHAGE 767
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAEeLKKAEEENKIkaeeakKEAEEDKKKAEE 1748
PHA03169 PHA03169
hypothetical protein; Provisional
 510-672 4.94e-05

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 46.89  E-value: 4.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  510 EGQDQEGPEEKKPPPRLPDEGDPAGRGQGAPPLPESEKEKQEPERGGEGKRPGQvlavgetehpqkVPEANGQPPVQPRK 589
Cdd:PHA03169   98 ESVGSPTPSPSGSAEELASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAP------------PESHNPSPNQQPSS 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  590 EDSRPGNRDPQPAAQArdsvelKALAADDGREPAQKAGGALWKPVESAAESDAGGKAGLPVQRPEAAEQREKKEAEQQGG 669
Cdd:PHA03169  166 FLQPSHEDSPEEPEPP------TSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTE 239


                  ...
gi 258645133  670 DQA 672
Cdd:PHA03169  240 PER 242
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 710-969 6.78e-05

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 46.99  E-value: 6.78e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  710 KRLLDQQEKLLAVIEEQHKEIRQQRQEGEEDKPKPDVQPEpgvavlrGQEEEAEHAGETLGDDPSQ----PLQPVLGAPR 785
Cdd:PTZ00449  486 KKLIKKSKKKLAPIEEEDSDKHDEPPEGPEASGLPPKAPG-------DKEGEEGEHEDSKESDEPKeggkPGETKEGEVG 558

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  786 GRPAPSQdmgQHLPGEVKVLPGRdladlPAGGSETEPQGAPIDLR--EDPKAAIKAAGAGKELVPGDLEAVHKAAPPEVP 863
Cdd:PTZ00449  559 KKPGPAK---EHKPSKIPTLSKK-----PEFPKDPKHPKDPEEPKkpKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESP 630

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  864 KSPEKQVAKavagQRqdvfgEGSEERKETGKEAMAPGA-DTQKEAVQPLVGAEAKDTKSRQSGPTKAPVQTQA------- 935
Cdd:PTZ00449  631 KSPKRPPPP----QR-----PSSPERPEGPKIIKSPKPpKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVldesfes 701

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 258645133  936 ---KFHPEPQAIFDTGQGSHPEVRSEAPRAVHIPPEE 969
Cdd:PTZ00449  702 ilkETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGD 738
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 433-601 1.01e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 46.30  E-value: 1.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  433 PVVVVAEDSQEKLKPAEDK---EVLEQAQIKGPVDVPGGEAPKEKQEAaQLDRPGQGIAvPMGEAHRHE------PPIPH 503
Cdd:NF033839  309 EVKPEPETPKPEVKPQLEKpkpEVKPQPEKPKPEVKPQLETPKPEVKP-QPEKPKPEVK-PQPEKPKPEvkpqpeTPKPE 386

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  504 DKVVVDEGQDQEGPEEKKPPPRL---PDEGDPAGRGQGAPPLPE----SEKEKQEPERGGEGKRPgQVLAVGETEHPQKV 576
Cdd:NF033839  387 VKPQPEKPKPEVKPQPEKPKPEVkpqPEKPKPEVKPQPEKPKPEvkpqPEKPKPEVKPQPEKPKP-EVKPQPETPKPEVK 465

                         170       180
                  ....*....|....*....|....*.
gi 258645133  577 PEANG-QPPVQPRKEDSRPGNRDPQP 601
Cdd:NF033839  466 PQPEKpKPEVKPQPEKPKPDNSKPQA 491
PTZ00121 PTZ00121
MAEBL; Provisional
 417-763 1.63e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.90  E-value: 1.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  417 AEGAMKVEAARLSVQDpvvvvAEDSQEKLKPAEDKEVLEQAQIKGPVDVPGGEAPKEKQEA---AQLDRPGQGIAVPMGE 493
Cdd:PTZ00121 1440 AEEAKKADEAKKKAEE-----AKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAkkkADEAKKAAEAKKKADE 1514

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  494 AHRHEPPIPHDKVVVDEGQDQEGPEEKKPPPRLPDEGDPAGRGQGAPPLPESEKEKQEPERGGEGKRPGQVLAVGETEHP 573
Cdd:PTZ00121 1515 AKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARI 1594

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  574 QKVPEANGQPPvQPRKEDSRPGNRDPQPAAQARDSVELKALAADDGREPAQKAGGAlwKPVESAAESDAGGKAGLPVQRP 653
Cdd:PTZ00121 1595 EEVMKLYEEEK-KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKA--EELKKAEEENKIKAAEEAKKAE 1671

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  654 E----------AAEQREKKEAEQQGGDQAGSKLEAEIKKLVAEAGRAEMLDHAVLLQVIQEQQVQQKRLLDQQEKLLAVI 723
Cdd:PTZ00121 1672 EdkkkaeeakkAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKK 1751

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 258645133  724 EEQHKEIRQQRQEgEEDKPKPDVQPEPGVAVLRGQEEEAE 763
Cdd:PTZ00121 1752 DEEEKKKIAHLKK-EEEKKAEEIRKEKEAVIEEELDEEDE 1790
PHA03169 PHA03169
hypothetical protein; Provisional
 461-679 5.86e-04

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 43.42  E-value: 5.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  461 GPVDVPGGEAPKEKQEAAQLDRPGQGIAVPMGEAHRHEPPIPHDkvvvDEGQDQEGPEEKKPPPRlPDEGDPAGRGQGAP 540
Cdd:PHA03169  111 AEELASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAPPES----HNPSPNQQPSSFLQPSH-EDSPEEPEPPTSEP 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  541 PlPESEK--EKQEPERGGEGKRPGQVLAVGETEHPQKVPEANGQPPVQPRKEDSRPGNRDPQPAAQardsvelkalaadd 618
Cdd:PHA03169  186 E-PDSPGppQSETPTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTEPEREGPPFPGH-------------- 250

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 258645133  619 gREPAQKAGGalWKPvesaaESDAGGKAGLPVQRPEAAEQREKKEAEQQGGDQAGSKLEAE 679
Cdd:PHA03169  251 -RSHSYTVVG--WKP-----STRPGGVPKLCLRCTSHPSHRSRLPEGQQSEDKVPRKYQAR 303
PRK10905 PRK10905
cell division protein DamX; Validated
 526-646 8.78e-04

cell division protein DamX; Validated


Pssm-ID: 236792 [Multi-domain]  Cd Length: 328  Bit Score: 42.62  E-value: 8.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  526 LPDEgdPAG----RGQGAPPlpesEKEKQEPERGGEGKRPGQVLAVGETEHPQKVPEANGQPPVQP--RKEDSRPGNRDP 599
Cdd:PRK10905  123 LPTE--PATvapvRNGNASR----QTAKTQTAERPATTRPARKQAVIEPKKPQATAKTEPKPVAQTpkRTEPAAPVASTK 196

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 258645133  600 QPAAQARDSVELKALAAddgrePAQKAggalwKPVESAAESDAGGKA 646
Cdd:PRK10905  197 APAATSTPAPKETATTA-----PVQTA-----SPAQTTATPAAGGKT 233
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 560-952 8.94e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.44  E-value: 8.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  560 RPGQVLAVGETEHPQKVPEANGQPPvqPRKEDSRPGNRDPQPAAQARDSVELKALAADDGREPAQKAGGALWKPVESAAE 639
Cdd:PRK07764  398 APSAAAAAPAAAPAPAAAAPAAAAA--PAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPE 475

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  640 SDAGGKAGLPVQRPEAAEQREKKEAEQQGGDQAGSKLE---AEIKKLVAEAGR---AEMLDHAVLLQVIQ-------EQQ 706
Cdd:PRK07764  476 PTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRerwPEILAAVPKRSRktwAILLPEATVLGVRGdtlvlgfSTG 555

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  707 VQQKRLLDQQ--EKLLAVIEEQHkeirqqrqeGEEDKPKPDVQPEPGVAVLRGQEEEAEHAGETLGDDPSQPlqpvlGAP 784
Cdd:PRK07764  556 GLARRFASPGnaEVLVTALAEEL---------GGDWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAP-----AAP 621

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  785 RGRPAPSQDMGQHLPGEVKVLPGRDLAdlPAGGSETEPQGAPIDLREDPKAAIKAAGAGKELVPGDLEAVHKAAPPEVPK 864
Cdd:PRK07764  622 AAPAAPAPAGAAAAPAEASAAPAPGVA--APEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPA 699

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  865 SPE-KQVAKAVAGQRQD------VFGEGSEERKETGKEAM----APGADTQKEAVQPLVGAEAKDTKSRQSGPTKAPVQT 933
Cdd:PRK07764  700 QPApAPAATPPAGQADDpaaqppQAAQGASAPSPAADDPVplppEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPP 779

                         410
                  ....*....|....*....
gi 258645133  934 QAKFHPEPQAIFDTGQGSH 952
Cdd:PRK07764  780 SEEEEMAEDDAPSMDDEDR 798
PHA03418 PHA03418
hypothetical E4 protein; Provisional
 500-598 2.65e-03

hypothetical E4 protein; Provisional


Pssm-ID: 177646 [Multi-domain]  Cd Length: 230  Bit Score: 40.88  E-value: 2.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  500 PIPHDKVVVDEGQDQEGPEEKKPPPRLPDEGD---PAGRGQGAPPLPESEKEK---------QEPERGGEGKRPGQVLAV 567
Cdd:PHA03418   68 PNGHNKPPVTKQPGGEGTEEDHQAPLAADADDdprPGKRSKADEHGPAPGRAAlapfkldldQDPLHGDPDPPPGATGGQ 147

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 258645133  568 GET-----EHPQKVP-----EANGQPPVQPRKEDSRPGNRD 598
Cdd:PHA03418  148 GEEppeggEESQPPLgegegAVEGHPPPLPPAPEPKPHNGD 188
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 505-777 3.21e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 41.52  E-value: 3.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133   505 KVVVDEGQD--QEGPEEKKPPPRLPDEGDPAGRGQGAPPLPESEKEKQEPERGGEGKRPGQVLAVGETEHPQKVPEANGQ 582
Cdd:TIGR00927  632 KGDVAEAEHtgERTGEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAERKGEQEGEGEIEAKEADHKGETE 711

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133   583 PPVQPRKEDSRPGNRDPQPAAQardsvelkalAADDGREPAQKAGGalwkpvESAAESDAGGKAGLPVQRPEAAEQREKK 662
Cdd:TIGR00927  712 AEEVEHEGETEAEGTEDEGEIE----------TGEEGEEVEDEGEG------EAEGKHEVETEGDRKETEHEGETEAEGK 775

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133   663 EAEQQGGDQAGSKLEA---EIKKLVAEAGRAEMLDHAVLLQVIQEQQVQQKRLLDQQEKlLAVIEEQHKEIRQQRQ--EG 737
Cdd:TIGR00927  776 EDEDEGEIQAGEDGEMkgdEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGE-QELNAENQGEAKQDEKgvDG 854

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 258645133   738 EEDKPKPDVQPEPGVAVLRGQEEEAEHAGETLGDDPSQPL 777
Cdd:TIGR00927  855 GGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPL 894
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 432-653 4.68e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 41.31  E-value: 4.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  432 DPVVVVAEDSQEKLKPAEDKEVLEQAQIKGPVDVPGGEAPKEKQEAAQLDRPGQGIAvPMGEAHRHEPPIPHDkvvvdeg 511
Cdd:PHA03307   52 AVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTP-PGPSSPDPPPPTPPP------- 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  512 qdqEGPEEKKPPPR---LPDEGDPAGRGQGAPPLPESEKEkqEPERGGEGKRPGQVLA--VGETEHPQKVPEANGQPPVQ 586
Cdd:PHA03307  124 ---ASPPPSPAPDLsemLRPVGSPGPPPAASPPAAGASPA--AVASDAASSRQAALPLssPEETARAPSSPPAEPPPSTP 198

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 258645133  587 PRKEDSRPGNRDPQPAAQARDSvelkalAADDGREPAQKAGGALWKPVES-AAESDAGGKAGLPVQRP 653
Cdd:PHA03307  199 PAAASPRPPRRSSPISASASSP------APAPGRSAADDAGASSSDSSSSeSSGCGWGPENECPLPRP 260
rne PRK10811
ribonuclease E; Reviewed
 731-977 7.83e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 40.41  E-value: 7.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  731 RQQRQEGEEDKPKPDVQPEPGVAvlrgqEEEAEHAGEtlgddPSQPLQPVLGAPRGRPAPsqdmgqhlpgeVKVLPGRDL 810
Cdd:PRK10811  849 RPQDVQVEEQREAEEVQVQPVVA-----EVPVAAAVE-----PVVSAPVVEAVAEVVEEP-----------VVVAEPQPE 907

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  811 ADLPAGGSETEPQGAPIDlrEDPKAAIKAAGAGKELVPGDLEAVHKAAPPEVPKSPEKQVAKAVAGQRQDVFGEGSEERK 890
Cdd:PRK10811  908 EVVVVETTHPEVIAAPVT--EQPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVA 985

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645133  891 ETgkEAMAPGADTQKEAVQPLVGAEAKDTKSRQSGP-TKAPVqtqakfhpepqaifdtgqgshPEVRSEAPRAVH-IPPE 968
Cdd:PRK10811  986 EV--AAEVETVTAVEPEVAPAQVPEATVEHNHATAPmTRAPA---------------------PEYVPEAPRHSDwQRPT 1042


                  ....*....
gi 258645133  969 EQHKGKGGA 977
Cdd:PRK10811 1043 FAFEGKGAA 1051
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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