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Conserved domains on  [gi|254540142|ref|NP_001156850|]
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protein TALPID3 isoform 1 [Mus musculus]

Protein Classification

TALPID3 domain-containing protein( domain architecture ID 12173090)

TALPID3 domain-containing protein

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
 117-1347 0e+00

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


:

Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 1841.06  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   117 DIFISQYTMGQKDALRTVLKQKAQSMPVFKAVKVHLFEDTSTEKNTVAQETETPPNRIDSATTVAAATAAAIATAAPLIK 196
Cdd:pfam15324    1 DIFISQYSAGQKDAVRAVLKQRAQSAPVFKEVKVQLLDDACSEKDAVGPEVQPSPSGIDSATTVAAATAAAIATTAPLIK 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   197 VQSDLEAKVNCVGELLTKLQETDKQLQRVTEHQASVQSKQEKVHCHDHDKQMNAFMEQHIRHLEKLQQQQIDIQTHFIDA 276
Cdd:pfam15324   81 VQSDLEAKVNSVSELLKKLQETDKQLQRVTEQQTSIQAKQEKSCCHDHEKQMNAFMEQRLRHLEKIQQQQIDIQTHLIGS 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   277 ALKASSLQLGMSTS-RAVGKY--SGKLGSPSVGSSVFSHNTFVSKRVPLSE--DTDFDGQKSPLETPAPRRFAPVPVSRD 351
Cdd:pfam15324  161 ALKAVSLQPSSVTSsRAVEKSgnSSEDESPAVGSASTSHHTFAPKQAPLAEvrDTQFDRQKSPLETPAPRRFAPVPVSRD 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   352 GKITKRESPTEEKENMEMNSPKGNVRLLEQVLNSNECLTRKTESSDITSLTQPKMGWNLEKRDSTETLHSQIFPSSEERG 431
Cdd:pfam15324  241 AKISKREPPKEEKENMETSSSKGNGRLLEQILNNQDSPTRKSESSVVTSLAMATVGWQPERSRESQPLEPQSFPSSEEPE 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   432 TAQVPVPKYNDVVHDLGQ-KKQASDML-----------------QIKQSPVTLRLSDHP------------------HNP 475
Cdd:pfam15324  321 TASVTVQKASDVLQDLGQlKKEMRSLLqtadafpvpnakstrssQSSRSLSPLPTPPPPppapismppvtavslaalSSP 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   476 ALLQTTN-TRSVLKDAAKILRGVQNNKKVLEENLEAIVRAKDGAAMYSFINALATNREMSEKIRIRKQVDEWIKIISAEI 554
Cdd:pfam15324  401 SVLQSTQpPRSMLKDAEKILRQVQNNKKVLEENLEAIIRAKDGAALHSFINALSTNRDMSEEIRIRKTVDEWIKTISKEI 480

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   555 QDELMRKDYEQKRFDPKNQRNKKALTM--------SRDIKANNQEKTVNRSVIPRSHYQKQTQEQFTSPPVRNLPASGPQ 626
Cdd:pfam15324  481 QDELARKDYEQKRFDQKNRRTAKAQAAkktsvrrqSKDIKANAQSKTPNKSVIPRKHFQKQAEEHFRKPPVRSMPASSLQ 560

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   627 KeRSGLLKSATTLQDEDYMLQIYGKPVYQGHRSTLKKGPYLRFSSPSPKAKPQRPRVIELVKGTKVKSAKTQTDFHAASR 706
Cdd:pfam15324  561 K-KEGPLKSTTSLQDEDYLLQVYGKAVYQGHRSTLKKGPYLRFNSPSPKSKPQRPKVIESVKGTKVKSARTQTDLHATKP 639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   707 MKMDSKIQHPITAlPHADQQYMVSPSREMPTVSGTLEGHLIPMAILLGQTQSNSDSMPPAGVTVNKPRPVTVTTSIPPAS 786
Cdd:pfam15324  640 VKTDSKMQHSVTA-PHQEQQYLFSPSREMPSQSGTLEGHLIPMAIPLGQTQSDSDSPPPAGVIVSKPHPVTVTTSIPPSS 718

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   787 RKGNAGVKKPNVAIVEMKSEKKDPPQLSVQILPSVDIDSVSYSSTDGASSP--PSPKEASLPPLHTWIQTPDFMKVDEEE 864
Cdd:pfam15324  719 RKPEPGVKKPNIALLEMKSEKKDPPQLTVQVLPSVDIDSVSCSSRDSSPSPvlPSPSEASPPLIQTWIQTPELMKEDEEE 798

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   865 VPLPGTNFDEVIDVIQEEEKRDEIPECSAPMLEFNRSVKVVPTKYNGPSFPPVVSAYHPTTDILDKVIERKETLENSLIQ 944
Cdd:pfam15324  799 VKFPGTNFDEVIDVIQDEEKEDEIPEFSEPPLEFNRSVKPPSTKYNGPPFPPVVSQPQPTTDILDKVIEQRETLENRLVD 878

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   945 WVEQEIMSRIISGLFPLQQQARLDASVSVSEASEPSASDIVAGTSSGALQRMVDARVPVNSDMVSHFVNEALTETIAVML 1024
Cdd:pfam15324  879 WVEQEIMARIISGMFPQQAQADPDASVSESEPSEPSTSDIVEAAGGGGLQLFVDAGVPVDSEMIRHFVNEALAETIAIML 958

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142  1025 ADREAERQRAAATSVPGDLSGTETNLLarvcAPVATPQPTPPCSP-SPVREHVRVKTPDSSPCESDPDaASSIKEIRVEK 1103
Cdd:pfam15324  959 GDREAQREPPVAASVPGDLPTKETLLP----TPVPTPQPTPPCSPpSPLKEPSPVKTPDSSPCVSEHD-FFPVKEIPPEK 1033

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142  1104 GSD-MPAVMLVSTPTRTPVATPPPAAALTPTLSETSIDKLKLSSPELPKPWDSGDLPLDEENPNSLQELPHPRAVVMSVA 1182
Cdd:pfam15324 1034 GADtGPAVSLVITPTVTPIATPPPAATPTPPLSENSIDKLKSPSPELPKPWEDSDLPLEEENPNSEQEELHPRAVVMSVA 1113

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142  1183 -NEEPESVDFSaqPAPPEPAPSAPLPEGTKAPSLQRVPSSGSSTLENTLS-TVTETETLDRHISEGEILFSCGQNLATKR 1260
Cdd:pfam15324 1114 rDEEPESVVLP--ASPPEPKPLAPPPLGAAPPSPPQSPSSSSSTLESSSSlTVTETETADRPISEGEILFSYGQMLAVRA 1191

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142  1261 PGD--LFLMNINDSLSSTLQDALEMEDDPPSEGQVIRRPHKKRHEDAIVALLTKQQRELLVSQQE----EDLDNSVGELS 1334
Cdd:pfam15324 1192 LEEggLFLPNLNDSLSSSLHDAQEMDYDPPSEGQVIRRPHKKAHHDPILSLLAKMNQGPLSSQQAvyhsEDLENSVGELS 1271

                         1290
                   ....*....|...
gi 254540142  1335 EGQRLVLKAAEDI 1347
Cdd:pfam15324 1272 EGQRPRLTAAAEN 1284
 
Name Accession Description Interval E-value
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
 117-1347 0e+00

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 1841.06  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   117 DIFISQYTMGQKDALRTVLKQKAQSMPVFKAVKVHLFEDTSTEKNTVAQETETPPNRIDSATTVAAATAAAIATAAPLIK 196
Cdd:pfam15324    1 DIFISQYSAGQKDAVRAVLKQRAQSAPVFKEVKVQLLDDACSEKDAVGPEVQPSPSGIDSATTVAAATAAAIATTAPLIK 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   197 VQSDLEAKVNCVGELLTKLQETDKQLQRVTEHQASVQSKQEKVHCHDHDKQMNAFMEQHIRHLEKLQQQQIDIQTHFIDA 276
Cdd:pfam15324   81 VQSDLEAKVNSVSELLKKLQETDKQLQRVTEQQTSIQAKQEKSCCHDHEKQMNAFMEQRLRHLEKIQQQQIDIQTHLIGS 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   277 ALKASSLQLGMSTS-RAVGKY--SGKLGSPSVGSSVFSHNTFVSKRVPLSE--DTDFDGQKSPLETPAPRRFAPVPVSRD 351
Cdd:pfam15324  161 ALKAVSLQPSSVTSsRAVEKSgnSSEDESPAVGSASTSHHTFAPKQAPLAEvrDTQFDRQKSPLETPAPRRFAPVPVSRD 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   352 GKITKRESPTEEKENMEMNSPKGNVRLLEQVLNSNECLTRKTESSDITSLTQPKMGWNLEKRDSTETLHSQIFPSSEERG 431
Cdd:pfam15324  241 AKISKREPPKEEKENMETSSSKGNGRLLEQILNNQDSPTRKSESSVVTSLAMATVGWQPERSRESQPLEPQSFPSSEEPE 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   432 TAQVPVPKYNDVVHDLGQ-KKQASDML-----------------QIKQSPVTLRLSDHP------------------HNP 475
Cdd:pfam15324  321 TASVTVQKASDVLQDLGQlKKEMRSLLqtadafpvpnakstrssQSSRSLSPLPTPPPPppapismppvtavslaalSSP 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   476 ALLQTTN-TRSVLKDAAKILRGVQNNKKVLEENLEAIVRAKDGAAMYSFINALATNREMSEKIRIRKQVDEWIKIISAEI 554
Cdd:pfam15324  401 SVLQSTQpPRSMLKDAEKILRQVQNNKKVLEENLEAIIRAKDGAALHSFINALSTNRDMSEEIRIRKTVDEWIKTISKEI 480

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   555 QDELMRKDYEQKRFDPKNQRNKKALTM--------SRDIKANNQEKTVNRSVIPRSHYQKQTQEQFTSPPVRNLPASGPQ 626
Cdd:pfam15324  481 QDELARKDYEQKRFDQKNRRTAKAQAAkktsvrrqSKDIKANAQSKTPNKSVIPRKHFQKQAEEHFRKPPVRSMPASSLQ 560

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   627 KeRSGLLKSATTLQDEDYMLQIYGKPVYQGHRSTLKKGPYLRFSSPSPKAKPQRPRVIELVKGTKVKSAKTQTDFHAASR 706
Cdd:pfam15324  561 K-KEGPLKSTTSLQDEDYLLQVYGKAVYQGHRSTLKKGPYLRFNSPSPKSKPQRPKVIESVKGTKVKSARTQTDLHATKP 639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   707 MKMDSKIQHPITAlPHADQQYMVSPSREMPTVSGTLEGHLIPMAILLGQTQSNSDSMPPAGVTVNKPRPVTVTTSIPPAS 786
Cdd:pfam15324  640 VKTDSKMQHSVTA-PHQEQQYLFSPSREMPSQSGTLEGHLIPMAIPLGQTQSDSDSPPPAGVIVSKPHPVTVTTSIPPSS 718

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   787 RKGNAGVKKPNVAIVEMKSEKKDPPQLSVQILPSVDIDSVSYSSTDGASSP--PSPKEASLPPLHTWIQTPDFMKVDEEE 864
Cdd:pfam15324  719 RKPEPGVKKPNIALLEMKSEKKDPPQLTVQVLPSVDIDSVSCSSRDSSPSPvlPSPSEASPPLIQTWIQTPELMKEDEEE 798

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   865 VPLPGTNFDEVIDVIQEEEKRDEIPECSAPMLEFNRSVKVVPTKYNGPSFPPVVSAYHPTTDILDKVIERKETLENSLIQ 944
Cdd:pfam15324  799 VKFPGTNFDEVIDVIQDEEKEDEIPEFSEPPLEFNRSVKPPSTKYNGPPFPPVVSQPQPTTDILDKVIEQRETLENRLVD 878

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   945 WVEQEIMSRIISGLFPLQQQARLDASVSVSEASEPSASDIVAGTSSGALQRMVDARVPVNSDMVSHFVNEALTETIAVML 1024
Cdd:pfam15324  879 WVEQEIMARIISGMFPQQAQADPDASVSESEPSEPSTSDIVEAAGGGGLQLFVDAGVPVDSEMIRHFVNEALAETIAIML 958

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142  1025 ADREAERQRAAATSVPGDLSGTETNLLarvcAPVATPQPTPPCSP-SPVREHVRVKTPDSSPCESDPDaASSIKEIRVEK 1103
Cdd:pfam15324  959 GDREAQREPPVAASVPGDLPTKETLLP----TPVPTPQPTPPCSPpSPLKEPSPVKTPDSSPCVSEHD-FFPVKEIPPEK 1033

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142  1104 GSD-MPAVMLVSTPTRTPVATPPPAAALTPTLSETSIDKLKLSSPELPKPWDSGDLPLDEENPNSLQELPHPRAVVMSVA 1182
Cdd:pfam15324 1034 GADtGPAVSLVITPTVTPIATPPPAATPTPPLSENSIDKLKSPSPELPKPWEDSDLPLEEENPNSEQEELHPRAVVMSVA 1113

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142  1183 -NEEPESVDFSaqPAPPEPAPSAPLPEGTKAPSLQRVPSSGSSTLENTLS-TVTETETLDRHISEGEILFSCGQNLATKR 1260
Cdd:pfam15324 1114 rDEEPESVVLP--ASPPEPKPLAPPPLGAAPPSPPQSPSSSSSTLESSSSlTVTETETADRPISEGEILFSYGQMLAVRA 1191

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142  1261 PGD--LFLMNINDSLSSTLQDALEMEDDPPSEGQVIRRPHKKRHEDAIVALLTKQQRELLVSQQE----EDLDNSVGELS 1334
Cdd:pfam15324 1192 LEEggLFLPNLNDSLSSSLHDAQEMDYDPPSEGQVIRRPHKKAHHDPILSLLAKMNQGPLSSQQAvyhsEDLENSVGELS 1271

                         1290
                   ....*....|...
gi 254540142  1335 EGQRLVLKAAEDI 1347
Cdd:pfam15324 1272 EGQRPRLTAAAEN 1284
 
Name Accession Description Interval E-value
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
 117-1347 0e+00

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 1841.06  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   117 DIFISQYTMGQKDALRTVLKQKAQSMPVFKAVKVHLFEDTSTEKNTVAQETETPPNRIDSATTVAAATAAAIATAAPLIK 196
Cdd:pfam15324    1 DIFISQYSAGQKDAVRAVLKQRAQSAPVFKEVKVQLLDDACSEKDAVGPEVQPSPSGIDSATTVAAATAAAIATTAPLIK 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   197 VQSDLEAKVNCVGELLTKLQETDKQLQRVTEHQASVQSKQEKVHCHDHDKQMNAFMEQHIRHLEKLQQQQIDIQTHFIDA 276
Cdd:pfam15324   81 VQSDLEAKVNSVSELLKKLQETDKQLQRVTEQQTSIQAKQEKSCCHDHEKQMNAFMEQRLRHLEKIQQQQIDIQTHLIGS 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   277 ALKASSLQLGMSTS-RAVGKY--SGKLGSPSVGSSVFSHNTFVSKRVPLSE--DTDFDGQKSPLETPAPRRFAPVPVSRD 351
Cdd:pfam15324  161 ALKAVSLQPSSVTSsRAVEKSgnSSEDESPAVGSASTSHHTFAPKQAPLAEvrDTQFDRQKSPLETPAPRRFAPVPVSRD 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   352 GKITKRESPTEEKENMEMNSPKGNVRLLEQVLNSNECLTRKTESSDITSLTQPKMGWNLEKRDSTETLHSQIFPSSEERG 431
Cdd:pfam15324  241 AKISKREPPKEEKENMETSSSKGNGRLLEQILNNQDSPTRKSESSVVTSLAMATVGWQPERSRESQPLEPQSFPSSEEPE 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   432 TAQVPVPKYNDVVHDLGQ-KKQASDML-----------------QIKQSPVTLRLSDHP------------------HNP 475
Cdd:pfam15324  321 TASVTVQKASDVLQDLGQlKKEMRSLLqtadafpvpnakstrssQSSRSLSPLPTPPPPppapismppvtavslaalSSP 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   476 ALLQTTN-TRSVLKDAAKILRGVQNNKKVLEENLEAIVRAKDGAAMYSFINALATNREMSEKIRIRKQVDEWIKIISAEI 554
Cdd:pfam15324  401 SVLQSTQpPRSMLKDAEKILRQVQNNKKVLEENLEAIIRAKDGAALHSFINALSTNRDMSEEIRIRKTVDEWIKTISKEI 480

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   555 QDELMRKDYEQKRFDPKNQRNKKALTM--------SRDIKANNQEKTVNRSVIPRSHYQKQTQEQFTSPPVRNLPASGPQ 626
Cdd:pfam15324  481 QDELARKDYEQKRFDQKNRRTAKAQAAkktsvrrqSKDIKANAQSKTPNKSVIPRKHFQKQAEEHFRKPPVRSMPASSLQ 560

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   627 KeRSGLLKSATTLQDEDYMLQIYGKPVYQGHRSTLKKGPYLRFSSPSPKAKPQRPRVIELVKGTKVKSAKTQTDFHAASR 706
Cdd:pfam15324  561 K-KEGPLKSTTSLQDEDYLLQVYGKAVYQGHRSTLKKGPYLRFNSPSPKSKPQRPKVIESVKGTKVKSARTQTDLHATKP 639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   707 MKMDSKIQHPITAlPHADQQYMVSPSREMPTVSGTLEGHLIPMAILLGQTQSNSDSMPPAGVTVNKPRPVTVTTSIPPAS 786
Cdd:pfam15324  640 VKTDSKMQHSVTA-PHQEQQYLFSPSREMPSQSGTLEGHLIPMAIPLGQTQSDSDSPPPAGVIVSKPHPVTVTTSIPPSS 718

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   787 RKGNAGVKKPNVAIVEMKSEKKDPPQLSVQILPSVDIDSVSYSSTDGASSP--PSPKEASLPPLHTWIQTPDFMKVDEEE 864
Cdd:pfam15324  719 RKPEPGVKKPNIALLEMKSEKKDPPQLTVQVLPSVDIDSVSCSSRDSSPSPvlPSPSEASPPLIQTWIQTPELMKEDEEE 798

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   865 VPLPGTNFDEVIDVIQEEEKRDEIPECSAPMLEFNRSVKVVPTKYNGPSFPPVVSAYHPTTDILDKVIERKETLENSLIQ 944
Cdd:pfam15324  799 VKFPGTNFDEVIDVIQDEEKEDEIPEFSEPPLEFNRSVKPPSTKYNGPPFPPVVSQPQPTTDILDKVIEQRETLENRLVD 878

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142   945 WVEQEIMSRIISGLFPLQQQARLDASVSVSEASEPSASDIVAGTSSGALQRMVDARVPVNSDMVSHFVNEALTETIAVML 1024
Cdd:pfam15324  879 WVEQEIMARIISGMFPQQAQADPDASVSESEPSEPSTSDIVEAAGGGGLQLFVDAGVPVDSEMIRHFVNEALAETIAIML 958

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142  1025 ADREAERQRAAATSVPGDLSGTETNLLarvcAPVATPQPTPPCSP-SPVREHVRVKTPDSSPCESDPDaASSIKEIRVEK 1103
Cdd:pfam15324  959 GDREAQREPPVAASVPGDLPTKETLLP----TPVPTPQPTPPCSPpSPLKEPSPVKTPDSSPCVSEHD-FFPVKEIPPEK 1033

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142  1104 GSD-MPAVMLVSTPTRTPVATPPPAAALTPTLSETSIDKLKLSSPELPKPWDSGDLPLDEENPNSLQELPHPRAVVMSVA 1182
Cdd:pfam15324 1034 GADtGPAVSLVITPTVTPIATPPPAATPTPPLSENSIDKLKSPSPELPKPWEDSDLPLEEENPNSEQEELHPRAVVMSVA 1113

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142  1183 -NEEPESVDFSaqPAPPEPAPSAPLPEGTKAPSLQRVPSSGSSTLENTLS-TVTETETLDRHISEGEILFSCGQNLATKR 1260
Cdd:pfam15324 1114 rDEEPESVVLP--ASPPEPKPLAPPPLGAAPPSPPQSPSSSSSTLESSSSlTVTETETADRPISEGEILFSYGQMLAVRA 1191

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540142  1261 PGD--LFLMNINDSLSSTLQDALEMEDDPPSEGQVIRRPHKKRHEDAIVALLTKQQRELLVSQQE----EDLDNSVGELS 1334
Cdd:pfam15324 1192 LEEggLFLPNLNDSLSSSLHDAQEMDYDPPSEGQVIRRPHKKAHHDPILSLLAKMNQGPLSSQQAvyhsEDLENSVGELS 1271

                         1290
                   ....*....|...
gi 254540142  1335 EGQRLVLKAAEDI 1347
Cdd:pfam15324 1272 EGQRPRLTAAAEN 1284
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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